John H Weiss
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Title(s) | Professor, Neurology |
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Address | 1001 Health Sciences Road Irvine CA 92697-3950
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Phone | (949) 824-6774, 8479 |
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vCard | Download vCard |
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Research Bibliographic
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration. Exp Neurol. 2020 03; 325:113161.
Ji SG, Medvedeva YV, Weiss JH. PMID: 31881218.
View in: PubMed Mentions: 1 Fields: Translation: AnimalsCells
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Rapid Intramitochondrial Zn2+ Accumulation in CA1 Hippocampal Pyramidal Neurons After Transient Global Ischemia: A Possible Contributor to Mitochondrial Disruption and Cell Death. J Neuropathol Exp Neurol. 2019 07 01; 78(7):655-664.
Yin HZ, Wang HL, Ji SG, Medvedeva YV, Tian G, Bazrafkan AK, Maki NZ, Akbari Y, Weiss JH. PMID: 31150090.
View in: PubMed Mentions: 5 Fields: Translation: AnimalsCells
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Mitochondrial Zn2+ Accumulation: A Potential Trigger of Hippocampal Ischemic Injury. Neuroscientist. 2019 04; 25(2):126-138.
Ji SG, Medvedeva YV, Wang HL, Yin HZ, Weiss JH. PMID: 29742958.
View in: PubMed Mentions: 4 Fields: Translation: HumansAnimalsCells
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Zn2+-induced disruption of neuronal mitochondrial function: Synergism with Ca2+, critical dependence upon cytosolic Zn2+ buffering, and contributions to neuronal injury. Exp Neurol. 2018 04; 302:181-195.
Ji SG, Weiss JH. PMID: 29355498.
View in: PubMed Mentions: 3 Fields: Translation: AnimalsCells
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Differential Vulnerability of CA1 versus CA3 Pyramidal Neurons After Ischemia: Possible Relationship to Sources of Zn2+ Accumulation and Its Entry into and Prolonged Effects on Mitochondria. J Neurosci. 2017 01 18; 37(3):726-737.
Medvedeva YV, Ji SG, Yin HZ, Weiss JH. PMID: 28100752.
View in: PubMed Mentions: 18 Fields: Translation: AnimalsCells
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Training stem cells for treatment of malignant brain tumors. World J Stem Cells. 2014 Sep 26; 6(4):432-40.
Li SC, Kabeer MH, Vu LT, Keschrumrus V, Yin HZ, Dethlefs BA, Zhong JF, Weiss JH, Loudon WG. PMID: 25258664.
View in: PubMed Mentions:
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Intrathecal infusion of BMAA induces selective motor neuron damage and astrogliosis in the ventral horn of the spinal cord. Exp Neurol. 2014 Nov; 261:1-9.
Yin HZ, Yu S, Hsu CI, Liu J, Acab A, Wu R, Tao A, Chiang BJ, Weiss JH. PMID: 24918341.
View in: PubMed Mentions: 9 Fields: Translation: HumansAnimalsCells
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Intramitochondrial Zn2+ accumulation via the Ca2+ uniporter contributes to acute ischemic neurodegeneration. Neurobiol Dis. 2014 Aug; 68:137-44.
Medvedeva YV, Weiss JH. PMID: 24787898.
View in: PubMed Mentions: 12 Fields: Translation: AnimalsCells
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Mechanisms of rapid reactive oxygen species generation in response to cytosolic Ca2+ or Zn2+ loads in cortical neurons. PLoS One. 2013; 8(12):e83347.
Clausen A, McClanahan T, Ji SG, Weiss JH. PMID: 24340096.
View in: PubMed Mentions: 17 Fields: Translation: AnimalsCells
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Cultivating stem cells for treating amyotrophic lateral sclerosis. World J Stem Cells. 2012 Dec 26; 4(12):117-9.
Li SC, Yin HZ, Loudon WG, Weiss JH. PMID: 23516096.
View in: PubMed Mentions:
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A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse. Muscle Nerve. 2013 Feb; 47(2):260-70.
Nalbandian A, Llewellyn KJ, Badadani M, Yin HZ, Nguyen C, Katheria V, Watts G, Mukherjee J, Vesa J, Caiozzo V, Mozaffar T, Weiss JH, Kimonis VE. PMID: 23169451.
View in: PubMed Mentions: 24 Fields: Translation: AnimalsCells
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The homozygote VCP(R¹55H/R¹55H) mouse model exhibits accelerated human VCP-associated disease pathology. PLoS One. 2012; 7(9):e46308.
Nalbandian A, Llewellyn KJ, Kitazawa M, Yin HZ, Badadani M, Khanlou N, Edwards R, Nguyen C, Mukherjee J, Mozaffar T, Watts G, Weiss J, Kimonis VE. PMID: 23029473.
View in: PubMed Mentions: 20 Fields: Translation: HumansAnimalsCells
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Cancer stem cells from a rare form of glioblastoma multiforme involving the neurogenic ventricular wall. Cancer Cell Int. 2012 Sep 20; 12(1):41.
Li SC, Vu LT, Ho HW, Yin HZ, Keschrumrus V, Lu Q, Wang J, Zhang H, Ma Z, Stover A, Weiss JH, Schwartz PH, Loudon WG. PMID: 22995409.
View in: PubMed Mentions:
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TNF-a triggers rapid membrane insertion of Ca(2+) permeable AMPA receptors into adult motor neurons and enhances their susceptibility to slow excitotoxic injury. Exp Neurol. 2012 Dec; 238(2):93-102.
Yin HZ, Hsu CI, Yu S, Rao SD, Sorkin LS, Weiss JH. PMID: 22921461.
View in: PubMed Mentions: 23 Fields: Translation: AnimalsCells
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17ß-Estradiol prevents cell death and mitochondrial dysfunction by an estrogen receptor-dependent mechanism in astrocytes after oxygen-glucose deprivation/reperfusion. Free Radic Biol Med. 2012 Jun 1-15; 52(11-12):2151-60.
Guo J, Duckles SP, Weiss JH, Li X, Krause DN. PMID: 22554613.
View in: PubMed Mentions: 22 Fields: Translation: AnimalsCells
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Marked synergism between mutant SOD1 and glutamate transport inhibition in the induction of motor neuronal degeneration in spinal cord slice cultures. Brain Res. 2012 Apr 11; 1448:153-62.
Yin HZ, Weiss JH. PMID: 22370146.
View in: PubMed Mentions: 6 Fields: Translation: AnimalsCells
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Ca permeable AMPA channels in diseases of the nervous system. Front Mol Neurosci. 2011; 4:42.
Weiss JH. PMID: 22102834.
View in: PubMed Mentions:
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Zinc: new clues to diverse roles in brain ischemia. Trends Pharmacol Sci. 2011 Aug; 32(8):480-6.
Shuttleworth CW, Weiss JH. PMID: 21621864.
View in: PubMed Mentions: 52 Fields: Translation: HumansCells
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Sensitive and selective detection of zinc ions in neuronal vesicles using PYDPY1, a simple turn-on dipyrrin. Chem Commun (Camb). 2011 Jul 07; 47(25):7107-9.
Mei Y, Frederickson CJ, Giblin LJ, Weiss JH, Medvedeva Y, Bentley PA. PMID: 21614400.
View in: PubMed Mentions: 7 Fields: Translation: AnimalsCells
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Zn²+ chelation improves recovery by delaying spreading depression-like events. Neuroreport. 2010 Nov 17; 21(16):1060-4.
Carter RE, Weiss JH, Shuttleworth CW. PMID: 20856149.
View in: PubMed Mentions: 1 Fields: Translation: Animals
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Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord. PLoS One. 2010 Jul 29; 5(7):e11852.
Rossi SL, Nistor G, Wyatt T, Yin HZ, Poole AJ, Weiss JH, Gardener MJ, Dijkstra S, Fischer DF, Keirstead HS. PMID: 20686613.
View in: PubMed Mentions: 39 Fields: Translation: HumansAnimalsCells
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Estrogen-receptor-mediated protection of cerebral endothelial cell viability and mitochondrial function after ischemic insult in vitro. J Cereb Blood Flow Metab. 2010 Mar; 30(3):545-54.
Guo J, Krause DN, Horne J, Weiss JH, Li X, Duckles SP. PMID: 19861973.
View in: PubMed Mentions: 27 Fields: Translation: AnimalsCells
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Mitochondrial dysfunction in CA1 hippocampal neurons of the UBE3A deficient mouse model for Angelman syndrome. Neurosci Lett. 2011 Jan 07; 487(2):129-33.
Su H, Fan W, Coskun PE, Vesa J, Gold JA, Jiang YH, Potluri P, Procaccio V, Acab A, Weiss JH, Wallace DC, Kimonis VE. PMID: 19563863.
View in: PubMed Mentions: 27 Fields: Translation: AnimalsCells
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Contributions of Ca2+ and Zn2+ to spreading depression-like events and neuronal injury. J Neurochem. 2009 May; 109 Suppl 1:145-52.
Dietz RM, Weiss JH, Shuttleworth CW. PMID: 19393021.
View in: PubMed Mentions: 14 Fields: Translation: HumansAnimalsCells
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Intracellular Zn2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia. J Neurosci. 2009 Jan 28; 29(4):1105-14.
Medvedeva YV, Lin B, Shuttleworth CW, Weiss JH. PMID: 19176819.
View in: PubMed Mentions: 65 Fields: Translation: AnimalsCells
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BMAA--an unusual cyanobacterial neurotoxin. Amyotroph Lateral Scler. 2009; 10 Suppl 2:50-5.
Vyas KJ, Weiss JH. PMID: 19929732.
View in: PubMed Mentions: 6 Fields: Translation: HumansAnimalsCells
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Zn2+ influx is critical for some forms of spreading depression in brain slices. J Neurosci. 2008 Aug 06; 28(32):8014-24.
Dietz RM, Weiss JH, Shuttleworth CW. PMID: 18685026.
View in: PubMed Mentions: 36 Fields: Translation: AnimalsCells
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Mechanisms of seizure-induced 'transcriptional channelopathy' of hyperpolarization-activated cyclic nucleotide gated (HCN) channels. Neurobiol Dis. 2008 Feb; 29(2):297-305.
Richichi C, Brewster AL, Bender RA, Simeone TA, Zha Q, Yin HZ, Weiss JH, Baram TZ. PMID: 17964174.
View in: PubMed Mentions: 37 Fields: Translation: Animals
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Intrathecal infusion of a Ca(2+)-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS. Exp Neurol. 2007 Oct; 207(2):177-85.
Yin HZ, Tang DT, Weiss JH. PMID: 17719032.
View in: PubMed Mentions: 15 Fields: Translation: AnimalsCells
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BMAA selectively injures motor neurons via AMPA/kainate receptor activation. Exp Neurol. 2006 Sep; 201(1):244-52.
Rao SD, Banack SA, Cox PA, Weiss JH. PMID: 16764863.
View in: PubMed Mentions: 52 Fields: Translation: HumansAnimalsCells
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Calcium-permeable AMPA channels in neurodegenerative disease and ischemia. Curr Opin Neurobiol. 2006 Jun; 16(3):281-7.
Kwak S, Weiss JH. PMID: 16698262.
View in: PubMed Mentions: 100 Fields: Translation: HumansAnimalsCells
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Tumor necrosis-factor-alpha (TNF-alpha) induces rapid insertion of Ca2+-permeable alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA)/kainate (Ca-A/K) channels in a subset of hippocampal pyramidal neurons. Exp Neurol. 2005 Jun; 193(2):384-93.
Ogoshi F, Yin HZ, Kuppumbatti Y, Song B, Amindari S, Weiss JH. PMID: 15869941.
View in: PubMed Mentions: 53 Fields: Translation: AnimalsCells
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Method for identifying neuronal cells suffering zinc toxicity by use of a novel fluorescent sensor. J Neurosci Methods. 2004 Oct 15; 139(1):79-89.
Frederickson CJ, Burdette SC, Frederickson CJ, Sensi SL, Weiss JH, Yin HZ, Balaji RV, Truong-Tran AQ, Bedell E, Prough DS, Lippard SJ. PMID: 15351524.
View in: PubMed Mentions: 11 Fields: Translation: AnimalsCells
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Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis. Trends Neurosci. 2004 Jan; 27(1):17-23.
Rao SD, Weiss JH. PMID: 14698606.
View in: PubMed Mentions: 36 Fields: Translation: HumansAnimalsCells
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Heterogeneity of Ca2+-permeable AMPA/kainate channel expression in hippocampal pyramidal neurons: fluorescence imaging and immunocytochemical assessment. J Neurosci. 2003 Nov 19; 23(33):10521-30.
Ogoshi F, Weiss JH. PMID: 14627636.
View in: PubMed Mentions: 20 Fields: Translation: AnimalsCells
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Reverse transcription-PCR analysis of laser-captured cells points to potential paracrine and autocrine actions of neurotrophins in pancreatic cancer. Clin Cancer Res. 2003 Nov 01; 9(14):5127-36.
Ketterer K, Rao S, Friess H, Weiss J, Büchler MW, Korc M. PMID: 14613990.
View in: PubMed Mentions: 40 Fields: Translation: HumansCells
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A sodium zinc exchange mechanism is mediating extrusion of zinc in mammalian cells. J Biol Chem. 2004 Feb 06; 279(6):4278-84.
Ohana E, Segal D, Palty R, Ton-That D, Moran A, Sensi SL, Weiss JH, Hershfinkel M, Sekler I. PMID: 14581475.
View in: PubMed Mentions: 19 Fields: Translation: HumansAnimalsCells
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A new mitochondrial fluorescent zinc sensor. Cell Calcium. 2003 Sep; 34(3):281-4.
Sensi SL, Ton-That D, Weiss JH, Rothe A, Gee KR. PMID: 12887975.
View in: PubMed Mentions: 28 Fields: Translation: AnimalsCells
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Modulation of mitochondrial function by endogenous Zn2+ pools. Proc Natl Acad Sci U S A. 2003 May 13; 100(10):6157-62.
Sensi SL, Ton-That D, Sullivan PG, Jonas EA, Gee KR, Kaczmarek LK, Weiss JH. PMID: 12724524.
View in: PubMed Mentions: 116 Fields: Translation: AnimalsCells
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Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons. J Neurosci. 2003 Apr 01; 23(7):2627-33.
Rao SD, Yin HZ, Weiss JH. PMID: 12684448.
View in: PubMed Mentions: 31 Fields: Translation: AnimalsCells
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Zn2+ currents are mediated by calcium-permeable AMPA/kainate channels in cultured murine hippocampal neurones. J Physiol. 2002 Aug 15; 543(Pt 1):35-48.
Jia Y, Jeng JM, Sensi SL, Weiss JH. PMID: 12181280.
View in: PubMed Mentions: 34 Fields: Translation: AnimalsCells
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Mitochondrial sequestration and Ca(2+)-dependent release of cytosolic Zn(2+) loads in cortical neurons. Neurobiol Dis. 2002 Jul; 10(2):100-8.
Sensi SL, Ton-That D, Weiss JH. PMID: 12127148.
View in: PubMed Mentions: 27 Fields: Translation: AnimalsCells
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Blockade of Ca2+-permeable AMPA/kainate channels decreases oxygen-glucose deprivation-induced Zn2+ accumulation and neuronal loss in hippocampal pyramidal neurons. J Neurosci. 2002 Feb 15; 22(4):1273-9.
Yin HZ, Sensi SL, Ogoshi F, Weiss JH. PMID: 11850455.
View in: PubMed Mentions: 44 Fields: Translation: AnimalsCells
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Zn(2+): a novel ionic mediator of neural injury in brain disease. Trends Pharmacol Sci. 2000 Oct; 21(10):395-401.
Weiss JH, Sensi SL, Koh JY. PMID: 11050320.
View in: PubMed Mentions: 117 Fields: Translation: HumansAnimalsCells
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Year | Publications |
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2000 | 1 | 2002 | 3 | 2003 | 6 | 2004 | 2 | 2005 | 1 | 2006 | 2 | 2007 | 2 | 2008 | 1 | 2009 | 5 | 2010 | 2 | 2011 | 3 | 2012 | 7 | 2013 | 1 | 2014 | 3 | 2017 | 1 | 2018 | 2 | 2019 | 2 |
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Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
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