Dennis D Cunningham
|
Title(s) | Professor Emeritus, Microbiology and Molecular Genetics |
---|
Address | 1001 Health Sciences Road Irvine CA 92697-3950
|
---|
Phone | (949) 824-8349, 7074, 52 |
---|
vCard | Download vCard |
---|
|
|
Research Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.)
Click a Field or Translation tag to filter the publications.
-
Geldanamycin specifically modulates thrombin-mediated morphological changes in mouse neuroblasts. J Neurochem. 2002 Feb; 80(4):715-8.
Pai KS, Cunningham DD. PMID: 11841578.
View in: PubMed Mentions:
-
Thrombin receptor signaling to cytoskeleton requires Hsp90. J Biol Chem. 2001 Aug 31; 276(35):32642-7.
Pai KS, Mahajan VB, Lau A, Cunningham DD. PMID: 11413145.
View in: PubMed Mentions:
-
Creatine kinase, an ATP-generating enzyme, is required for thrombin receptor signaling to the cytoskeleton. Proc Natl Acad Sci U S A. 2000 Oct 24; 97(22):12062-7.
Mahajan VB, Pai KS, Lau A, Cunningham DD. PMID: 11050237.
View in: PubMed Mentions: 21 Fields: Translation: AnimalsCells
-
Injury-related factors and conditions down-regulate the thrombin receptor (PAR-1) in a human neuronal cell line. J Neurochem. 1998 Sep; 71(3):1034-50.
Weinstein JR, Lau AL, Brass LF, Cunningham DD. PMID: 9721728.
View in: PubMed Mentions: 8 Fields: Translation: HumansCells
-
Signaling pathways involved in thrombin-induced cell protection. J Biol Chem. 1998 May 22; 273(21):12746-52.
Donovan FM, Cunningham DD. PMID: 9582299.
View in: PubMed Mentions: 13 Fields: Translation: HumansAnimalsCells
-
Thrombin causes a marked delay in skeletal myogenesis that correlates with the delayed expression of myogenin and p21CIP1/WAF1. J Biol Chem. 1997 Sep 26; 272(39):24117-20.
Guttridge DC, Lau A, Tran L, Cunningham DD. PMID: 9305855.
View in: PubMed Mentions: 3 Fields: Translation: AnimalsCells
-
Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. J Neurosci. 1997 Jul 15; 17(14):5316-26.
Donovan FM, Pike CJ, Cotman CW, Cunningham DD. PMID: 9204916.
View in: PubMed Mentions: 69 Fields: Translation: HumansAnimalsCells
-
Regulation of neurons and astrocytes by thrombin and protease nexin-1. Relationship to brain injury. Adv Exp Med Biol. 1997; 425:67-75.
Cunningham DD, Donovan FM. PMID: 9433490.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimalsCells
-
Characterization of the human protease nexin-1 promoter and its regulation by Sp1 through a G/C-rich activation domain. J Neurochem. 1996 Aug; 67(2):498-507.
Guttridge DC, Cunningham DD. PMID: 8764573.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimalsCells
-
Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro. J Neurochem. 1996 Apr; 66(4):1374-82.
Pike CJ, Vaughan PJ, Cunningham DD, Cotman CW. PMID: 8627288.
View in: PubMed Mentions: 15 Fields: Translation: AnimalsCells
-
Decreases in protease nexins in Alzheimer's disease brain. Neurobiol Aging. 1995 Jul-Aug; 16(4):557-62.
Choi BH, Kim RC, Vaughan PJ, Lau A, Van Nostrand WE, Cotman CW, Cunningham DD. PMID: 8544905.
View in: PubMed Mentions: 9 Fields: Translation: HumansCells
-
Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. J Neurosci. 1995 Jul; 15(7 Pt 2):5389-401.
Vaughan PJ, Pike CJ, Cotman CW, Cunningham DD. PMID: 7623161.
View in: PubMed Mentions: 52 Fields: Translation: AnimalsCells
-
Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. J Neurosci. 1995 Apr; 15(4):2906-19.
Weinstein JR, Gold SJ, Cunningham DD, Gall CM. PMID: 7722637.
View in: PubMed Mentions: 51 Fields: Translation: AnimalsCells
-
Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: involvement of tyrosine phosphorylation. J Neurochem. 1995 Feb; 64(2):583-91.
Grabham P, Cunningham DD. PMID: 7830051.
View in: PubMed Mentions: 18 Fields: Translation: AnimalsCells
-
Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease. Brain Res. 1994 Dec 30; 668(1-2):160-70.
Vaughan PJ, Su J, Cotman CW, Cunningham DD. PMID: 7704602.
View in: PubMed Mentions: 15 Fields: Translation: Humans
-
Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid beta-protein precursor. J Biol Chem. 1994 Sep 09; 269(36):22623-7.
Davis-Salinas J, Saporito-Irwin SM, Donovan FM, Cunningham DD, Van Nostrand WE. PMID: 8077213.
View in: PubMed Mentions: 13 Fields: Translation: HumansCells
-
Regulation of protease nexin-1 target protease specificity by collagen type IV. J Biol Chem. 1994 Jun 24; 269(25):17199-205.
Donovan FM, Vaughan PJ, Cunningham DD. PMID: 8006028.
View in: PubMed Mentions: 5 Fields: Translation: HumansCells
-
Co-distribution of protease nexin-1 and protease nexin-2 in brains of non-human primates. Brain Res. 1993 Oct 29; 626(1-2):90-8.
Wagner SL, Van Nostrand WE, Lau AL, Farrow JS, Suzuki M, Bartus RT, Schuppek R, Nguyen A, Cotman CW, Cunningham DD. PMID: 8281456.
View in: PubMed Mentions: 5 Fields: Translation: Animals
-
Protease nexin-1, a thrombin inhibitor, is regulated by interleukin-1 and dexamethasone in normal human fibroblasts. J Biol Chem. 1993 Sep 05; 268(25):18966-74.
Guttridge DC, Lau AL, Cunningham DD. PMID: 8360185.
View in: PubMed Mentions: 6 Fields: Translation: HumansCells
-
Protease nexin-1 and thrombin: injury-related processes in the brain. Thromb Haemost. 1993 Jul 01; 70(1):168-71.
Cunningham DD, Pulliam L, Vaughan PJ. PMID: 8236095.
View in: PubMed Mentions: 8 Fields: Translation: HumansCells
-
Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors. J Biol Chem. 1993 Feb 15; 268(5):3720-7.
Vaughan PJ, Cunningham DD. PMID: 8429047.
View in: PubMed Mentions: 15 Fields: Translation: HumansCells
-
Regulation of neuronal cells and astrocytes by protease nexin-1 and thrombin. Ann N Y Acad Sci. 1992 Dec 31; 674:228-36.
Cunningham DD. PMID: 1288365.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimalsCells
-
Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease. Neuroscience. 1992 Jun; 48(4):763-77.
Cummings BJ, Su JH, Geddes JW, Van Nostrand WE, Wagner SL, Cunningham DD, Cotman CW. PMID: 1378573.
View in: PubMed Mentions: 21 Fields: Translation: HumansCells
-
Regulation of protease nexin-1 activity by heparin and heparan sulfate. Adv Exp Med Biol. 1992; 313:297-306.
Cunningham DD, Wagner SL, Farrell DH. PMID: 1442266.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimalsCells
-
The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2. Proc Natl Acad Sci U S A. 1991 Nov 15; 88(22):10302-6.
Van Nostrand WE, Farrow JS, Wagner SL, Bhasin R, Goldgaber D, Cotman CW, Cunningham DD. PMID: 1946448.
View in: PubMed Mentions: 7 Fields: Translation: HumansCells
-
Protease nexin-2/amyloid beta-protein precursor in blood is a platelet-specific protein. Biochem Biophys Res Commun. 1991 Feb 28; 175(1):15-21.
Van Nostrand WE, Schmaier AH, Farrow JS, Cines DB, Cunningham DD. PMID: 1900151.
View in: PubMed Mentions: 11 Fields: Translation: HumansCells
-
Inhibitors of urokinase and thrombin in cultured neural cells. J Neurochem. 1991 Jan; 56(1):234-42.
Wagner SL, Lau AL, Nguyen A, Mimuro J, Loskutoff DJ, Isackson PJ, Cunningham DD. PMID: 1987320.
View in: PubMed Mentions: 4 Fields: Translation: HumansCells
-
Platelet protease nexin-2/amyloid beta-protein precursor. Possible pathologic and physiologic functions. Ann N Y Acad Sci. 1991; 640:140-4.
Van Nostrand WE, Schmaier AH, Farrow JS, Cunningham DD. PMID: 1776731.
View in: PubMed Mentions: 7 Fields: Translation: HumansCells
-
Protease nexin-1. Localization in the human brain suggests a protective role against extravasated serine proteases. Am J Pathol. 1990 Oct; 137(4):741-7.
Choi BH, Suzuki M, Kim T, Wagner SL, Cunningham DD. PMID: 2221008.
View in: PubMed Mentions: 15 Fields: Translation: Humans
-
Immunopurification and protease inhibitory properties of protease nexin-2/amyloid beta-protein precursor. J Biol Chem. 1990 Jun 15; 265(17):9591-4.
Van Nostrand WE, Wagner SL, Farrow JS, Cunningham DD. PMID: 2112543.
View in: PubMed Mentions: 26 Fields: Translation: HumansCells
-
Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein. Science. 1990 May 11; 248(4956):745-8.
Van Nostrand WE, Schmaier AH, Farrow JS, Cunningham DD. PMID: 2110384.
View in: PubMed Mentions: 51 Fields: Translation: HumansCells
-
Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1. J Neurochem. 1990 May; 54(5):1735-43.
Cavanaugh KP, Gurwitz D, Cunningham DD, Bradshaw RA. PMID: 1691280.
View in: PubMed Mentions: 30 Fields: Translation: AnimalsCells
-
Neurite outgrowth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition. J Cell Physiol. 1990 Jan; 142(1):155-62.
Gurwitz D, Cunningham DD. PMID: 2298818.
View in: PubMed Mentions: 10 Fields: Translation: AnimalsCells
-
Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease. Proc Natl Acad Sci U S A. 1989 Nov; 86(21):8284-8.
Wagner SL, Geddes JW, Cotman CW, Lau AL, Gurwitz D, Isackson PJ, Cunningham DD. PMID: 2813392.
View in: PubMed Mentions: 15 Fields: Translation: HumansCells
-
Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor. Nature. 1989 Oct 12; 341(6242):546-9.
Van Nostrand WE, Wagner SL, Suzuki M, Choi BH, Farrow JS, Geddes JW, Cotman CW, Cunningham DD. PMID: 2507928.
View in: PubMed Mentions: 64 Fields: Translation: HumansCells
-
Protease nexin-1 complexes and inhibits T cell serine proteinase-1. Biochem Biophys Res Commun. 1989 May 30; 161(1):300-4.
Gurwitz D, Simon MM, Fruth U, Cunningham DD. PMID: 2786418.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimalsCells
-
Binding of protease nexin-1 to the fibroblast surface alters its target proteinase specificity. J Biol Chem. 1989 Jan 05; 264(1):611-5.
Wagner SL, Lau AL, Cunningham DD. PMID: 2642483.
View in: PubMed Mentions: 8 Fields: Translation: HumansCells
-
Proteolytic regulation of neurite outgrowth from neuroblastoma cells by thrombin and protease nexin-1. J Cell Biochem. 1989 Jan; 39(1):55-64.
Cunningham DD, Gurwitz D. PMID: 2654147.
View in: PubMed Mentions: 7 Fields: Translation: Cells
-
Thrombin modulates and reverses neuroblastoma neurite outgrowth. Proc Natl Acad Sci U S A. 1988 May; 85(10):3440-4.
Gurwitz D, Cunningham DD. PMID: 2835773.
View in: PubMed Mentions: 40 Fields: Translation: HumansAnimalsCells
-
Purification of a form of protease nexin 1 that binds heparin with a low affinity. Biochemistry. 1988 Mar 22; 27(6):2176-81.
Van Nostrand WE, Wagner SL, Cunningham DD. PMID: 3378053.
View in: PubMed Mentions: 2 Fields: Translation: HumansCells
-
Monoclonal antibodies to protease nexin 1 that differentially block its inhibition of target proteases. Biochemistry. 1988 Mar 22; 27(6):2173-6.
Wagner SL, Van Nostrand WE, Lau AL, Cunningham DD. PMID: 3378052.
View in: PubMed Mentions: 2 Fields: Translation: Animals
-
Functional and structural similarities between protease nexin I and C1 inhibitor. J Biol Chem. 1988 Mar 15; 263(8):3979-83.
Van Nostrand WE, McKay LD, Baker JB, Cunningham DD. PMID: 3279027.
View in: PubMed Mentions: 6 Fields: Translation: HumansCells
-
Effects of fibroblasts and endothelial cells on inactivation of target proteases by protease nexin-1, heparin cofactor II, and C1-inhibitor. J Cell Biochem. 1988 Mar; 36(3):199-207.
Hiramoto SA, Cunningham DD. PMID: 3379101.
View in: PubMed Mentions: Fields: Translation: HumansAnimalsCells
-
Localization of protease nexin-1 on the fibroblast extracellular matrix. J Cell Physiol. 1988 Feb; 134(2):179-88.
Farrell DH, Wagner SL, Yuan RH, Cunningham DD. PMID: 3279057.
View in: PubMed Mentions: 13 Fields: Translation: HumansCells
-
Glycosaminoglycans on fibroblasts accelerate thrombin inhibition by protease nexin-1. Biochem J. 1987 Jul 15; 245(2):543-50.
Farrell DH, Cunningham DD. PMID: 2959275.
View in: PubMed Mentions: 8 Fields: Translation: HumansCells
This graph shows the total number of publications by year. To see the data as text, click here.
This graph shows the total number of publications by year. To return to the graph, click here.
Year | Publications |
---|
1991 | 4 | 1992 | 3 | 1993 | 4 | 1994 | 3 | 1995 | 4 | 1996 | 2 | 1997 | 3 | 1998 | 2 | 2000 | 1 | 2001 | 1 | 2002 | 1 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
newest
oldest
line numbers
double spacing
all authors
publication IDs
|
Derived automatically from this person's publications.
_
People in Profiles who have published with this person.
_
People who share similar concepts with this person.
_
Search Department
_
|