Vladimir Jivkov Kefalov

Title(s)Professor, Ophth Research
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-0552
Emailvkefalov@uci.edu
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    Collapse Research 
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    Opsin signaling in mammalian rod photoreceptors
    NIH R01EY030912Jun 1, 2020 - Apr 30, 2024
    Role: Principal Investigator
    CALCIUM HOMEOSTASIS IN MAMMALIAN ROD AND CONE PHOTORECEPTORS
    NIH R01EY027387Jul 1, 2017 - Jun 30, 2021
    Role: Principal Investigator
    PIGMENT DEPHOSPHORYLATION IN MAMMALIAN ROD AND CONE PHOTORECEPTORS
    NIH R01EY025696Aug 1, 2016 - Jul 31, 2020
    Role: Principal Investigator
    FASEB SRC on Biology and Chemistry of Vision
    NIH R13EY023475Apr 1, 2013 - Mar 31, 2014
    Role: Principal Investigator
    CALCIUM AND ADAPTATION IN MAMMALIAN CONE PHOTORECEPTORS
    NIH R21EY019543Sep 1, 2009 - Aug 31, 2011
    Role: Principal Investigator
    MECHANISMS OF ADAPTATION IN MAMMALIAN CONES
    NIH R01EY019312Dec 1, 2008 - Jul 31, 2019
    Role: Principal Investigator
    Retinoids in Vision
    NIH R01EY009339Aug 1, 1992 - Aug 31, 2025
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Redox-Responsive Hyaluronic Acid-Based Nanogels for the Topical Delivery of the Visual Chromophore to Retinal Photoreceptors. ACS Omega. 2021 Mar 09; 6(9):6172-6184. Laradji AM, Kolesnikov AV, Karakoçak BB, Kefalov VJ, Ravi N. PMID: 33718708.
      View in: PubMed   Mentions:
    2. Function of mammalian M-cones depends on the level of CRALBP in Müller cells. J Gen Physiol. 2021 Jan 04; 153(1). Kolesnikov AV, Kiser PD, Palczewski K, Kefalov VJ. PMID: 33216847.
      View in: PubMed   Mentions:    Fields:    
    3. Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca2+ uptake in photoreceptor mitochondria. Sci Rep. 2020 09 29; 10(1):16041. Bisbach CM, Hutto RA, Poria D, Cleghorn WM, Abbas F, Vinberg F, Kefalov VJ, Hurley JB, Brockerhoff SE. PMID: 32994451.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    4. Mislocalization of cone nuclei impairs cone function in mice. FASEB J. 2020 08; 34(8):10242-10249. Xue Y, Razafsky D, Hodzic D, Kefalov VJ. PMID: 32539195.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Thyroid hormone receptors mediate two distinct mechanisms of long-wavelength vision. Proc Natl Acad Sci U S A. 2020 06 30; 117(26):15262-15269. Volkov LI, Kim-Han JS, Saunders LM, Poria D, Hughes AEO, Kefalov VJ, Parichy DM, Corbo JC. PMID: 32541022.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    6. Light deprivation reduces the severity of experimental diabetic retinopathy. Neurobiol Dis. 2020 04; 137:104754. Thebeau C, Zhang S, Kolesnikov AV, Kefalov VJ, Semenkovich CF, Rajagopal R. PMID: 31978605.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    7. Phosphorylation at Serine 21 in G protein-coupled receptor kinase 1 (GRK1) is required for normal kinetics of dark adaption in rod but not cone photoreceptors. FASEB J. 2020 02; 34(2):2677-2690. Kolesnikov AV, Chrispell JD, Osawa S, Kefalov VJ, Weiss ER. PMID: 31908030.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    8. Two-photon microperimetry: sensitivity of human photoreceptors to infrared light. Biomed Opt Express. 2019 Sep 01; 10(9):4551-4567. Ruminski D, Palczewska G, Nowakowski M, Zielinska A, Kefalov VJ, Komar K, Palczewski K, Wojtkowski M. PMID: 31565509.
      View in: PubMed   Mentions:
    9. Sensitivity of Mammalian Cone Photoreceptors to Infrared Light. Neuroscience. 2019 09 15; 416:100-108. Vinberg F, Palczewska G, Zhang J, Komar K, Wojtkowski M, Kefalov VJ, Palczewski K. PMID: 31400484.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    10. Photoreceptors in a mouse model of Leigh syndrome are capable of normal light-evoked signaling. J Biol Chem. 2019 08 16; 294(33):12432-12443. Gospe SM, Travis AM, Kolesnikov AV, Klingeborn M, Wang L, Kefalov VJ, Arshavsky VY. PMID: 31248988.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    11. A Mixture of U.S. Food and Drug Administration-Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness. Invest Ophthalmol Vis Sci. 2019 04 01; 60(5):1442-1453. Leinonen H, Choi EH, Gardella A, Kefalov VJ, Palczewski K. PMID: 30947334.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    12. Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones. FASEB J. 2019 04; 33(4):5782-5792. Kiser PD, Kolesnikov AV, Kiser JZ, Dong Z, Chaurasia B, Wang L, Summers SA, Hoang T, Blackshaw S, Peachey NS, Kefalov VJ, Palczewski K. PMID: 30645148.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    13. Apo-Opsin Exists in Equilibrium Between a Predominant Inactive and a Rare Highly Active State. J Neurosci. 2019 01 09; 39(2):212-223. Sato S, Jastrzebska B, Engel A, Palczewski K, Kefalov VJ. PMID: 30459230.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    14. Investigating the Ca2+-dependent and Ca2+-independent mechanisms for mammalian cone light adaptation. Sci Rep. 2018 10 26; 8(1):15864. Vinberg F, Kefalov VJ. PMID: 30367097.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    15. Examining the Role of Cone-expressed RPE65 in Mouse Cone Function. Sci Rep. 2018 09 21; 8(1):14201. Kolesnikov AV, Tang PH, Kefalov VJ. PMID: 30242264.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    16. Regulation of calcium homeostasis in the outer segments of rod and cone photoreceptors. Prog Retin Eye Res. 2018 11; 67:87-101. Vinberg F, Chen J, Kefalov VJ. PMID: 29883715.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    17. LRIT1 Modulates Adaptive Changes in Synaptic Communication of Cone Photoreceptors. Cell Rep. 2018 03 27; 22(13):3562-3573. Sarria I, Cao Y, Wang Y, Ingram NT, Orlandi C, Kamasawa N, Kolesnikov AV, Pahlberg J, Kefalov VJ, Sampath AP, Martemyanov KA. PMID: 29590623.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    18. Guanylate cyclase-activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors. J Biol Chem. 2018 05 11; 293(19):7457-7465. Vinberg F, Peshenko IV, Chen J, Dizhoor AM, Kefalov VJ. PMID: 29549122.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    19. Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function. J Gen Physiol. 2018 04 02; 150(4):571-590. Kiser PD, Zhang J, Sharma A, Angueyra JM, Kolesnikov AV, Badiee M, Tochtrop GP, Kinoshita J, Peachey NS, Li W, Kefalov VJ, Palczewski K. PMID: 29500274.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    20. GUCY2D Cone-Rod Dystrophy-6 Is a "Phototransduction Disease" Triggered by Abnormal Calcium Feedback on Retinal Membrane Guanylyl Cyclase 1. J Neurosci. 2018 03 21; 38(12):2990-3000. Sato S, Peshenko IV, Olshevskaya EV, Kefalov VJ, Dizhoor AM. PMID: 29440533.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    21. Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors. Proc Natl Acad Sci U S A. 2017 11 07; 114(45):E9675-E9684. Kolesnikov AV, Orban T, Jin H, Brooks C, Hofmann L, Dong Z, Sokolov M, Palczewski K, Kefalov VJ. PMID: 29078372.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    22. The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision. Elife. 2017 06 26; 6. Vinberg F, Wang T, De Maria A, Zhao H, Bassnett S, Chen J, Kefalov VJ. PMID: 28650316.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    23. Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets. Curr Biol. 2017 Jul 10; 27(13):2014-2022.e6. Potter C, Zhu W, Razafsky D, Ruzycki P, Kolesnikov AV, Doggett T, Kefalov VJ, Betleja E, Mahjoub MR, Hodzic D. PMID: 28625779.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    24. The role of retinol dehydrogenase 10 in the cone visual cycle. Sci Rep. 2017 05 24; 7(1):2390. Xue Y, Sato S, Razafsky D, Sahu B, Shen SQ, Potter C, Sandell LL, Corbo JC, Palczewski K, Maeda A, Hodzic D, Kefalov VJ. PMID: 28539612.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    25. The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones. Vis Neurosci. 2017 01; 34:E004. Sato S, Frederiksen R, Cornwall MC, Kefalov VJ. PMID: 28359344.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    26. The Na(+)/Ca(2+), K(+) exchanger 2 modulates mammalian cone phototransduction. Sci Rep. 2016 09 01; 6:32521. Sakurai K, Vinberg F, Wang T, Chen J, Kefalov VJ. PMID: 27580676.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    27. cis Retinol oxidation regulates photoreceptor access to the retina visual cycle and cone pigment regeneration. J Physiol. 2016 11 15; 594(22):6753-6765. Sato S, Kefalov VJ. PMID: 27385534.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    28. Rhodopsin kinase and arrestin binding control the decay of photoactivated rhodopsin and dark adaptation of mouse rods. J Gen Physiol. 2016 07; 148(1):1-11. Frederiksen R, Nymark S, Kolesnikov AV, Berry JD, Adler L, Koutalos Y, Kefalov VJ, Cornwall MC. PMID: 27353443.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    29. Lamin B1 and lamin B2 are long-lived proteins with distinct functions in retinal development. Mol Biol Cell. 2016 06 15; 27(12):1928-37. Razafsky D, Ward C, Potter C, Zhu W, Xue Y, Kefalov VJ, Fong LG, Young SG, Hodzic D. PMID: 27075175.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    30. The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility. J Biol Chem. 2016 Apr 15; 291(16):8721-34. Ding XQ, Thapa A, Ma H, Xu J, Elliott MH, Rodgers KK, Smith ML, Wang JS, Pittler SJ, Kefalov VJ. PMID: 26893377.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    31. Circadian and light-driven regulation of rod dark adaptation. Sci Rep. 2015 Dec 02; 5:17616. Xue Y, Shen SQ, Corbo JC, Kefalov VJ. PMID: 26626567.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    32. Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2. Curr Biol. 2015 Dec 07; 25(23):3048-57. Enright JM, Toomey MB, Sato SY, Temple SE, Allen JR, Fujiwara R, Kramlinger VM, Nagy LD, Johnson KM, Xiao Y, How MJ, Johnson SL, Roberts NW, Kefalov VJ, Guengerich FP, Corbo JC. PMID: 26549260.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    33. Retinol dehydrogenase 8 and ATP-binding cassette transporter 4 modulate dark adaptation of M-cones in mammalian retina. J Physiol. 2015 Nov 15; 593(22):4923-41. Kolesnikov AV, Maeda A, Tang PH, Imanishi Y, Palczewski K, Kefalov VJ. PMID: 26350353.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    34. Systemic Retinaldehyde Treatment Corrects Retinal Oxidative Stress, Rod Dysfunction, and Impaired Visual Performance in Diabetic Mice. Invest Ophthalmol Vis Sci. 2015 Oct; 56(11):6294-303. Berkowitz BA, Kern TS, Bissig D, Patel P, Bhatia A, Kefalov VJ, Roberts R. PMID: 26431483.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    35. Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies. Genome Biol. 2015 Sep 01; 16:171. Ruzycki PA, Tran NM, Kefalov VJ, Kolesnikov AV, Chen S. PMID: 26324254.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    36. A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease. Hum Mol Genet. 2015 Oct 15; 24(20):5915-29. Vinberg F, Wang T, Molday RS, Chen J, Kefalov VJ. PMID: 26246500.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    37. Simultaneous ex vivo functional testing of two retinas by in vivo electroretinogram system. J Vis Exp. 2015 May 06; (99):e52855. Vinberg F, Kefalov V. PMID: 25992809.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    38. Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior. Elife. 2015 Apr 16; 4:e06358. Sarria I, Pahlberg J, Cao Y, Kolesnikov AV, Kefalov VJ, Sampath AP, Martemyanov KA. PMID: 25879270.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    39. Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations. Hum Mol Genet. 2015 Jun 01; 24(11):3220-37. Zhang N, Tsybovsky Y, Kolesnikov AV, Rozanowska M, Swider M, Schwartz SB, Stone EM, Palczewska G, Maeda A, Kefalov VJ, Jacobson SG, Cideciyan AV, Palczewski K. PMID: 25712131.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    40. Regulation of mammalian cone phototransduction by recoverin and rhodopsin kinase. J Biol Chem. 2015 Apr 03; 290(14):9239-50. Sakurai K, Chen J, Khani SC, Kefalov VJ. PMID: 25673692.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    41. Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling. PLoS One. 2015; 10(2):e0117129. Tracy CM, Kolesnikov AV, Blake DR, Chen CK, Baehr W, Kefalov VJ, Willardson BM. PMID: 25659125.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    42. CRALBP supports the mammalian retinal visual cycle and cone vision. J Clin Invest. 2015 Feb; 125(2):727-38. Xue Y, Shen SQ, Jui J, Rupp AC, Byrne LC, Hattar S, Flannery JG, Corbo JC, Kefalov VJ. PMID: 25607845.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    43. Autophagy supports color vision. Autophagy. 2015; 11(10):1821-32. Zhou Z, Vinberg F, Schottler F, Doggett TA, Kefalov VJ, Ferguson TA. PMID: 26292183.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    44. Human infrared vision is triggered by two-photon chromophore isomerization. Proc Natl Acad Sci U S A. 2014 Dec 16; 111(50):E5445-54. Palczewska G, Vinberg F, Stremplewski P, Bircher MP, Salom D, Komar K, Zhang J, Cascella M, Wojtkowski M, Kefalov VJ, Palczewski K. PMID: 25453064.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    45. Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo. FASEB J. 2015 Feb; 29(2):554-64. Berkowitz BA, Gorgis J, Patel A, Baameur F, Gurevich VV, Craft CM, Kefalov VJ, Roberts R. PMID: 25351983.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    46. Chromophore supply rate-limits mammalian photoreceptor dark adaptation. J Neurosci. 2014 Aug 20; 34(34):11212-21. Wang JS, Nymark S, Frederiksen R, Estevez ME, Shen SQ, Corbo JC, Cornwall MC, Kefalov VJ. PMID: 25143602.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    47. Ex vivo ERG analysis of photoreceptors using an in vivo ERG system. Vision Res. 2014 Aug; 101:108-17. Vinberg F, Kolesnikov AV, Kefalov VJ. PMID: 24959652.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    48. FASEB Science Research Conference on Biology and Chemistry of Vision. FASEB J. 2014 Jun; 28(6):2395-7. Kefalov VJ, Arshavsky VY. PMID: 24891609.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    49. DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice. FASEB J. 2014 Aug; 28(8):3780-91. Sundermeier TR, Zhang N, Vinberg F, Mustafi D, Kohno H, Golczak M, Bai X, Maeda A, Kefalov VJ, Palczewski K. PMID: 24812086.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    50. R9AP overexpression alters phototransduction kinetics in iCre75 mice. Invest Ophthalmol Vis Sci. 2014 Mar 06; 55(3):1339-47. Sundermeier TR, Vinberg F, Mustafi D, Bai X, Kefalov VJ, Palczewski K. PMID: 24526444.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    51. An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina. PLoS One. 2013; 8(12):e82276. Cain MD, Vo BQ, Kolesnikov AV, Kefalov VJ, Culican SM, Kerschensteiner D, Blumer KJ. PMID: 24349243.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    52. P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis. Hum Mol Genet. 2014 Apr 01; 23(7):1723-41. Sakami S, Kolesnikov AV, Kefalov VJ, Palczewski K. PMID: 24214395.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    53. Cone phosphodiesterase-6a' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6ß-deficient rd10 mouse. J Neurosci. 2013 Jul 17; 33(29):11745-53. Deng WT, Sakurai K, Kolandaivelu S, Kolesnikov AV, Dinculescu A, Li J, Zhu P, Liu X, Pang J, Chiodo VA, Boye SL, Chang B, Ramamurthy V, Kefalov VJ, Hauswirth WW. PMID: 23864662.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    54. Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors. J Neurosci. 2013 May 01; 33(18):7941-51. Lai CW, Kolesnikov AV, Frederick JM, Blake DR, Jiang L, Stewart JS, Chen CK, Barrow JR, Baehr W, Kefalov VJ, Willardson BM. PMID: 23637185.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    55. Reprogramming of adult rod photoreceptors prevents retinal degeneration. Proc Natl Acad Sci U S A. 2013 Jan 29; 110(5):1732-7. Montana CL, Kolesnikov AV, Shen SQ, Myers CA, Kefalov VJ, Corbo JC. PMID: 23319618.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    56. Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization. J Clin Invest. 2013 Jan; 123(1):121-37. Zhang N, Kolesnikov AV, Jastrzebska B, Mustafi D, Sawada O, Maeda T, Genoud C, Engel A, Kefalov VJ, Palczewski K. PMID: 23221340.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    57. Store-operated channels regulate intracellular calcium in mammalian rods. J Physiol. 2012 Aug 01; 590(15):3465-81. Molnar T, Barabas P, Birnbaumer L, Punzo C, Kefalov V, Križaj D. PMID: 22674725.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    58. Transretinal ERG recordings from mouse retina: rod and cone photoresponses. J Vis Exp. 2012 Mar 14; (61). Kolesnikov AV, Kefalov VJ. PMID: 22453300.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    59. Signaling states of rhodopsin in rod disk membranes lacking transducin ß?-complex. Invest Ophthalmol Vis Sci. 2012 Mar; 53(3):1225-33. Lomonosova E, Kolesnikov AV, Kefalov VJ, Kisselev OG. PMID: 22266510.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    60. Rod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approaches. J Biol Chem. 2012 Jan 13; 287(3):1635-41. Kefalov VJ. PMID: 22074928.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    61. Variation in rhodopsin kinase expression alters the dim flash response shut off and the light adaptation in rod photoreceptors. Invest Ophthalmol Vis Sci. 2011 Aug 29; 52(9):6793-800. Sakurai K, Young JE, Kefalov VJ, Khani SC. PMID: 21474765.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    62. Role of guanylyl cyclase modulation in mouse cone phototransduction. J Neurosci. 2011 Jun 01; 31(22):7991-8000. Sakurai K, Chen J, Kefalov VJ. PMID: 21632921.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    63. G-protein betagamma-complex is crucial for efficient signal amplification in vision. J Neurosci. 2011 Jun 01; 31(22):8067-77. Kolesnikov AV, Rikimaru L, Hennig AK, Lukasiewicz PD, Fliesler SJ, Govardovskii VI, Kefalov VJ, Kisselev OG. PMID: 21632928.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    64. The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein. J Neurosci. 2011 May 25; 31(21):7900-9. Kolesnikov AV, Tang PH, Parker RO, Crouch RK, Kefalov VJ. PMID: 21613504.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    65. Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle. J Neurosci. 2011 Mar 23; 31(12):4714-9. Parker R, Wang JS, Kefalov VJ, Crouch RK. PMID: 21430170.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    66. The cone-specific visual cycle. Prog Retin Eye Res. 2011 Mar; 30(2):115-28. Wang JS, Kefalov VJ. PMID: 21111842.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimalsCells
    67. Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons. J Neurosci. 2010 Oct 13; 30(41):13784-93. Cao Y, Kolesnikov AV, Masuho I, Kefalov VJ, Martemyanov KA. PMID: 20943919.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    68. Age-related deterioration of rod vision in mice. J Neurosci. 2010 Aug 18; 30(33):11222-31. Kolesnikov AV, Fan J, Crouch RK, Kefalov VJ. PMID: 20720130.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    69. Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism. J Neurosci. 2010 Feb 17; 30(7):2496-503. Fan J, Sakurai K, Chen CK, Rohrer B, Wu BX, Yau KW, Kefalov V, Crouch RK. PMID: 20164334.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    70. Single-cell suction recordings from mouse cone photoreceptors. J Vis Exp. 2010 Jan 05; (35). Wang JS, Kefalov VJ. PMID: 20051937.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    71. Physiological studies of the interaction between opsin and chromophore in rod and cone visual pigments. Methods Mol Biol. 2010; 652:95-114. Kefalov VJ, Cornwall MC, Fain GL. PMID: 20552424.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    72. Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viability. Invest Ophthalmol Vis Sci. 2010 Mar; 51(3):1728-37. Whitcomb T, Sakurai K, Brown BM, Young JE, Sheflin L, Dlugos C, Craft CM, Kefalov VJ, Khani SC. PMID: 19834036.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCellsPHPublic Health
    73. Functional interchangeability of rod and cone transducin alpha-subunits. Proc Natl Acad Sci U S A. 2009 Oct 20; 106(42):17681-6. Deng WT, Sakurai K, Liu J, Dinculescu A, Li J, Pang J, Min SH, Chiodo VA, Boye SL, Chang B, Kefalov VJ, Hauswirth WW. PMID: 19815523.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    74. An alternative pathway mediates the mouse and human cone visual cycle. Curr Biol. 2009 Oct 13; 19(19):1665-9. Wang JS, Kefalov VJ. PMID: 19781940.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    75. Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa. J Neurosci. 2009 Aug 05; 29(31):9748-60. Yamashita T, Liu J, Gao J, LeNoue S, Wang C, Kaminoh J, Bowne SJ, Sullivan LS, Daiger SP, Zhang K, Fitzgerald ME, Kefalov VJ, Zuo J. PMID: 19657028.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    76. Intra-retinal visual cycle required for rapid and complete cone dark adaptation. Nat Neurosci. 2009 Mar; 12(3):295-302. Wang JS, Estevez ME, Cornwall MC, Kefalov VJ. PMID: 19182795.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    77. Quantal noise from human red cone pigment. Nat Neurosci. 2008 May; 11(5):565-71. Fu Y, Kefalov V, Luo DG, Xue T, Yau KW. PMID: 18425122.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    78. Signaling properties of a short-wave cone visual pigment and its role in phototransduction. J Neurosci. 2007 Sep 19; 27(38):10084-93. Shi G, Yau KW, Chen J, Kefalov VJ. PMID: 17881515.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    79. Molecular properties of rhodopsin and rod function. J Biol Chem. 2007 Mar 02; 282(9):6677-84. Imai H, Kefalov V, Sakurai K, Chisaka O, Ueda Y, Onishi A, Morizumi T, Fu Y, Ichikawa K, Nakatani K, Honda Y, Chen J, Yau KW, Shichida Y. PMID: 17194706.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    80. Breaking the covalent bond--a pigment property that contributes to desensitization in cones. Neuron. 2005 Jun 16; 46(6):879-90. Kefalov VJ, Estevez ME, Kono M, Goletz PW, Crouch RK, Cornwall MC, Yau KW. PMID: 15953417.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    81. Role of visual pigment properties in rod and cone phototransduction. Nature. 2003 Oct 02; 425(6957):526-31. Kefalov V, Fu Y, Marsh-Armstrong N, Yau KW. PMID: 14523449.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    82. Use of retinal analogues for the study of visual pigment function. Methods Enzymol. 2002; 343:29-48. Crouch RK, Kefalov V, Gärtner W, Cornwall MC. PMID: 11665574.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    83. Role of noncovalent binding of 11-cis-retinal to opsin in dark adaptation of rod and cone photoreceptors. Neuron. 2001 Mar; 29(3):749-55. Kefalov VJ, Crouch RK, Cornwall MC. PMID: 11301033.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    84. Effect of 11-cis 13-demethylretinal on phototransduction in bleach-adapted rod and cone photoreceptors. J Gen Physiol. 2000 Aug; 116(2):283-97. Corson DW, Kefalov VJ, Cornwall MC, Crouch RK. PMID: 10919871.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    85. Electrophysiological methods for measurement of activation of phototransduction by bleached visual pigment in salamander photoreceptors. Methods Enzymol. 2000; 316:224-52. Cornwall MC, Jones GJ, Kefalov VJ, Fain GL, Matthews HR. PMID: 10800678.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    86. Occupancy of the chromophore binding site of opsin activates visual transduction in rod photoreceptors. J Gen Physiol. 1999 Mar; 113(3):491-503. Kefalov VJ, Carter Cornwall M, Crouch RK. PMID: 10051522.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
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