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Timothy Scott Kern

Title(s)Professor, Ophthalmology
Phone(949) 824-5324
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    BLR&D Research Career Scientist Application
    VA IK6BX003604Oct 1, 2016 - Sep 30, 2021
    Role: Principal Investigator
    Novel therapies to inhibit diabetic retinopathy
    NIH/NEI R24EY024864Apr 1, 2015 - Mar 31, 2020
    Role: Principal Investigator
    Acetylation and diabetic retinopathy
    VA I01BX002117Apr 1, 2014 - Mar 31, 2018
    Role: Principal Investigator
    Role of Photoreceptors in the Pathogenesis of Diabetic Retinopathy
    NIH/NEI R01EY022938Sep 1, 2013 - May 31, 2022
    Role: Principal Investigator
    Global Characterization of Lysine Acetylation in Diabetic Retina
    NIH/NEI R21EY021595Jan 1, 2012 - Dec 31, 2013
    Role: Co-Principal Investigator
    PATHOGENESIS OF DIABETIC MICROVASCULAR COMPLICATIONS
    NIH/NIDDK P01DK057733Sep 1, 2000 - Aug 31, 2005
    Role: Principal Investigator
    Study of diabetic retinopathy
    NIH/NEI R56EY000300Dec 1, 1977 - Sep 29, 2010
    Role: Principal Investigator
    Study of diabetic retinopathy
    NIH/NEI R01EY000300Dec 1, 1977 - Sep 29, 2000
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Fu Z, Kern TS, Hellström A, Smith L. Fatty acid oxidation and photoreceptor metabolic needs. J Lipid Res. 2020 Feb 24. PMID: 32094231.
      View in: PubMed
    2. Fu Z, Chen CT, Cagnone G, Heckel E, Sun Y, Cakir B, Tomita Y, Huang S, Li Q, Britton W, Cho SS, Kern TS, Hellström A, Joyal JS, Smith LE. Dyslipidemia in retinal metabolic disorders. EMBO Mol Med. 2019 10; 11(10):e10473. PMID: 31486227.
      View in: PubMed
    3. Kern TS, Antonetti DA, Smith LEH. Pathophysiology of Diabetic Retinopathy: Contribution and Limitations of Laboratory Research. Ophthalmic Res. 2019; 62(4):196-202. PMID: 31362288.
      View in: PubMed
    4. Nahomi RB, Sampathkumar S, Myers AM, Elghazi L, Smith DG, Tang J, Lee CA, Kern TS, Nagaraj RH, Fort PE. The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice. Invest Ophthalmol Vis Sci. 2018 04 01; 59(5):2042-2053. PMID: 29677366.
      View in: PubMed
    5. Kern TS. Do photoreceptor cells cause the development of retinal vascular disease? Vision Res. 2017 10; 139:65-71. PMID: 28438678.
      View in: PubMed
    6. Veenstra A, Liu H, Lee CA, Du Y, Tang J, Kern TS. Diabetic Retinopathy: Retina-Specific Methods for Maintenance of Diabetic Rodents and Evaluation of Vascular Histopathology and Molecular Abnormalities. Curr Protoc Mouse Biol. 2015 Sep 01; 5(3):247-270. PMID: 26331759.
      View in: PubMed
    7. Liu H, Tang J, Du Y, Lee CA, Golczak M, Muthusamy A, Antonetti DA, Veenstra AA, Amengual J, von Lintig J, Palczewski K, Kern TS. Retinylamine Benefits Early Diabetic Retinopathy in Mice. J Biol Chem. 2015 Aug 28; 290(35):21568-79. PMID: 26139608.
      View in: PubMed
    8. Du Y, Cramer M, Lee CA, Tang J, Muthusamy A, Antonetti DA, Jin H, Palczewski K, Kern TS. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB J. 2015 May; 29(5):2194-204. PMID: 25667222.
      View in: PubMed
    9. Rajashekhar G, Ramadan A, Abburi C, Callaghan B, Traktuev DO, Evans-Molina C, Maturi R, Harris A, Kern TS, March KL. Regenerative therapeutic potential of adipose stromal cells in early stage diabetic retinopathy. PLoS One. 2014; 9(1):e84671. PMID: 24416262.
      View in: PubMed
    10. Li Y, Smith D, Li Q, Sheibani N, Huang S, Kern T, Nagaraj RH, Lin F. Antibody-mediated retinal pericyte injury: implications for diabetic retinopathy. Invest Ophthalmol Vis Sci. 2012 Aug 13; 53(9):5520-6. PMID: 22786897.
      View in: PubMed
    11. Sapieha P, Chen J, Stahl A, Seaward MR, Favazza TL, Juan AM, Hatton CJ, Joyal JS, Krah NM, Dennison RJ, Tang J, Kern TS, Akula JD, Smith LE. Omega-3 polyunsaturated fatty acids preserve retinal function in type 2 diabetic mice. Nutr Diabetes. 2012 Jul 23; 2:e36. PMID: 23448719.
      View in: PubMed
    12. Opreanu M, Tikhonenko M, Bozack S, Lydic TA, Reid GE, McSorley KM, Sochacki A, Perez GI, Esselman WJ, Kern T, Kolesnick R, Grant MB, Busik JV. The unconventional role of acid sphingomyelinase in regulation of retinal microangiopathy in diabetic human and animal models. Diabetes. 2011 Sep; 60(9):2370-8. PMID: 21771974.
      View in: PubMed
    13. Tang J, Kern TS. Inflammation in diabetic retinopathy. Prog Retin Eye Res. 2011 Sep; 30(5):343-58. PMID: 21635964.
      View in: PubMed
    14. Barber AJ, Antonetti DA, Kern TS, Reiter CE, Soans RS, Krady JK, Levison SW, Gardner TW, Bronson SK. The Ins2Akita mouse as a model of early retinal complications in diabetes. Invest Ophthalmol Vis Sci. 2005 Jun; 46(6):2210-8. PMID: 15914643.
      View in: PubMed
    15. Engerman RL, Kern TS. Hyperglycemia as a cause of diabetic retinopathy. Metabolism. 1986 Apr; 35(4 Suppl 1):20-3. PMID: 3083205.
      View in: PubMed
    16. Kern TS, Engerman RL. Microvascular metabolism in diabetes. Metabolism. 1986 Apr; 35(4 Suppl 1):24-7. PMID: 3083206.
      View in: PubMed
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