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Frank P K Hsu

Title(s)Clinical Professor, Neurosurgery
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-6966
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    1. Robotic Orthogonal Implantation of Responsive Neurostimulation (RNS) Depth Electrodes in the Mesial Temporal Lobe: Case Series. Oper Neurosurg (Hagerstown). 2020 Jul 01; 19(1):19-24. Chan AY, Tran DK, Paff MR, Urgun K, Hsu FPK, Vadera S. PMID: 31792508.
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    2. James T. Goodrich, MD, PhD, 1946-2020: a historical perspective and his contributions to craniopagus separation. J Neurosurg Pediatr. 2020 Jun 19; 1-7. Lehrich BM, Brown NJ, Shahrestani S, Sahyouni R, Hsu FPK. PMID: 32559740.
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    3. A Novel Robotic-Assisted Technique to Implant the Responsive Neurostimulation System. Oper Neurosurg (Hagerstown). 2020 Jun 01; 18(6):728-735. Tran DK, Paff M, Mnatsakanyan L, Sen-Gupta I, Lin JJ, Hsu FPK, Vadera S. PMID: 31538187.
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    4. A Retrospective Interventional Cohort Study to Assess the Safety and Efficacy of Sandostatin LAR for Treatment of Recurrent and/or Refractory Meningiomas. Front Neurol. 2020; 11:373. Hrachova M, Nguyen ENT, Fu BD, Dandekar MJ, Kong XT, Cadena G, Hsu FPK, Billimek J, Taylor TH, Bota DA. PMID: 32435228.
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    5. Endoscopic Anterior Skull Base Reconstruction: A Meta-Analysis and Systematic Review of Graft Type. World Neurosurg. 2020 Apr 21; 139:460-470. Abiri A, Abiri P, Goshtasbi K, Lehrich BM, Sahyouni R, Hsu FPK, Cadena G, Kuan EC. PMID: 32330621.
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    6. Advances in Noninvasive Neurodiagnostics. World Neurosurg. 2020 Mar 17; 139:1-3. Urgun K, Ball BZ, Hsu FPK. PMID: 32194266.
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    7. Multimodal management of giant cerebral aneurysms: review of literature and case presentation. Stroke Vasc Neurol. 2020; 5(1):22-28. Campos JK, Ball BZ, Cheaney Ii B, Sweidan AJ, Hasjim BJ, Hsu FPK, Wang AS, Lin LM. PMID: 32411404.
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    8. Endoscopic versus nonendoscopic surgery for resection of pituitary adenomas: a national database study. J Neurosurg. 2020 Mar 13; 1-9. Goshtasbi K, Lehrich BM, Abouzari M, Abiri A, Birkenbeuel J, Lan MY, Wang WH, Cadena G, Hsu FPK, Kuan EC. PMID: 32168478.
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    9. UC Care Check-A Postoperative Neurosurgery Operating Room Checklist: An Interrupted Time Series Study. J Healthc Qual. 2020 Jan 21. Lau CY, Seymann G, Imershein S, Amin A, Afsarmanesh N, Uppington J, Aledia A, Pretanvil S, Wilson B, Wong J, Varma J, Boggan J, Hsu FPK, Carter B, Berger M, Harrison JD. PMID: 31977363.
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    10. Two-year clinical outcomes associated with robotic-assisted subthalamic lead implantation in patients with Parkinson's disease. J Robot Surg. 2019 Sep 13. Paff M, Wang AS, Phielipp N, Vadera S, Morenkova A, Hermanowicz N, Hsu FPK. PMID: 31520275.
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    11. Visual and Endocrine Recovery Following Conservative and Surgical Treatment of Pituitary Apoplexy: A Meta-Analysis. World Neurosurg. 2019 Dec; 132:33-40. Goshtasbi K, Abiri A, Sahyouni R, Mahboubi H, Raefsky S, Kuan EC, Hsu FPK, Cadena G. PMID: 31470146.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Hyams grading as a predictor of metastasis and overall survival in esthesioneuroblastoma: a meta-analysis. Int Forum Allergy Rhinol. 2019 09; 9(9):1054-1062. Goshtasbi K, Abiri A, Abouzari M, Sahyouni R, Wang BY, Tajudeen BA, Hsu FPK, Cadena G, Kuan EC. PMID: 31251848.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Multiplexing of Theta and Alpha Rhythms in the Amygdala-Hippocampal Circuit Supports Pattern Separation of Emotional Information. Neuron. 2019 05 22; 102(4):887-898.e5. Zheng J, Stevenson RF, Mander BA, Mnatsakanyan L, Hsu FPK, Vadera S, Knight RT, Yassa MA, Lin JJ. PMID: 30979537.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Vision Outcomes in Early versus Late Surgical Intervention of Pituitary Apoplexy: Meta-Analysis. World Neurosurg. 2019 Jul; 127:52-57. Sahyouni R, Goshtasbi K, Choi E, Mahboubi H, Le R, Khahera AS, Hanna GK, Hatefi D, Hsu FP, Bhandarkar ND, Kuan EC, Cadena G. PMID: 30922898.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Cerebral Peduncle Volume and Motor Function Following Adult Hemispherectomy. World Neurosurg. 2019 06; 126:156-159. Chan AY, Urgun K, Tran DK, Kyong T, Hsu FPK, Vadera S. PMID: 30877000.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. The Impact of Unmet Communication and Education Needs on Neurosurgical Patient and Caregiver Experiences of Care: A Qualitative Exploratory Analysis. World Neurosurg. 2019 Feb; 122:e1528-e1535. Harrison JD, Seymann G, Imershein S, Amin A, Afsarmanesh N, Uppington J, Aledia A, Pretanvil S, Wilson B, Wong J, Varma J, Boggan J, Hsu FPK, Carter B, Martin N, Berger M, Lau CY. PMID: 30471444.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Deep brain stimulation for obsessive compulsive disorder: A review of results by anatomical target. Ment Illn. 2018 Nov 06; 10(2):7900. Borders C, Hsu F, Sweidan AJ, Matei ES, Bota RG. PMID: 30542526.
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    18. Somatic SMARCB1 Mutation in Sporadic Multiple Meningiomas: Case Report. Front Neurol. 2018; 9:919. Wang AS, Jamshidi AO, Oh N, Sahyouni R, Nowroozizadeh B, Kim R, Hsu FPK, Bota D. PMID: 30416484.
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    19. The Pearls and Pitfalls of Initiating a Neurosurgery Discharge Huddle: One Institution's Experience. Neurosurgery. 2018 09 01; 65(CN_suppl_1):58-61. Chan AY, Gannotta R, Hsu FPK, Vadera S. PMID: 31076786.
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    20. Therapeutic Immunization against Glioblastoma. Int J Mol Sci. 2018 Aug 27; 19(9). Schijns VEJC, Pretto C, Strik AM, Gloudemans-Rijkers R, Deviller L, Pierre D, Chung J, Dandekar M, Carrillo JA, Kong XT, Fu BD, Hsu FPK, Hofman FM, Chen TC, Zidovetzki R, Bota DA, Stathopoulos A. PMID: 30150597.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    21. Integrative Medicine as a Vital Component of Patient Care. Cureus. 2018 Aug 04; 10(8):e3098. Gannotta R, Malik S, Chan AY, Urgun K, Hsu F, Vadera S. PMID: 30338174.
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    22. Phase II study of ERC1671 plus bevacizumab versus bevacizumab plus placebo in recurrent glioblastoma: interim results and correlations with CD4+ T-lymphocyte counts. CNS Oncol. 2018 07 01; 7(3):CNS22. Bota DA, Chung J, Dandekar M, Carrillo JA, Kong XT, Fu BD, Hsu FP, Schönthal AH, Hofman FM, Chen TC, Zidovetzki R, Pretto C, Strik A, Schijns VE, Stathopoulos A. PMID: 30157683.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsCTClinical Trials
    23. Strategic hospital partnerships: improved access to care and increased epilepsy surgical volume. Neurosurg Focus. 2018 05; 44(5):E9. Vadera S, Chan AY, Mnatsankanyan L, Sazgar M, Sen-Gupta I, Lin J, Hsu FPK. PMID: 29712523.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. A novel integrative healing services approach for neurosurgery inpatients: Preliminary experiences and cost calculations. Interdiscip Neurosurg. 2018 Sep; 13:124-128. Roufail J, Sahyouni R, Malik S, Cadena G, Chen JW, Hsu FPK, Gannotta R, Vadera S. PMID: 30792957.
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    25. Intracranial meningioma with carcinoma tumor-to-tumor metastasis: two case reports. CNS Oncol. 2018 04; 7(2):CNS09. Pham JT, Kim RC, Nguyen A, Bota D, Kong XT, Vadera S, Hsu F, Carrillo JA. PMID: 29698064.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Accuracy and Efficacy for Robotic Assistance in Implanting Responsive Neurostimulation Device Electrodes in Bilateral Mesial Temporal Lobe Epilepsy. Oper Neurosurg (Hagerstown). 2018 03 01; 14(3):267-272. Chan AY, Mnatsakanyan L, Sazgar M, Sen-Gupta I, Lin JJ, Hsu FPK, Vadera S. PMID: 29462446.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Solid Variant of Aneurysmal Bone Cyst of the Temporal Bone. Ann Otol Rhinol Laryngol. 2018 Apr; 127(4):285-290. Saez N, Sharma GK, Barnes CH, Lu Y, Hsu FP, Huoh KC, Djalilian HR, Lin HW. PMID: 29436237.
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    28. Intracranial Myeloid Sarcoma Metastasis Mimicking Acute Subdural Hematoma. Case Rep Surg. 2017; 2017:3056285. Gill AS, Gill R, Kaloostian P, Elias D, Roufail JS, Cruz AS, Pelargos PE, Hsu FPK, Kim RC, Ayer RE, Ghostine S. PMID: 29201484.
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    29. Aneurysm treatment practice patterns for newly appointed dual-trained cerebrovascular/endovascular neurosurgeons: Comparison of open surgical to neuroendovascular procedures in the first 2 years of academic practice. Surg Neurol Int. 2017; 8:154. Jiang B, Bender MT, Hasjim B, Hsu FPK, Tamargo RJ, Huang J, Colby GP, Coon AL, Lin LM. PMID: 28808603.
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    30. Language recovery after epilepsy surgery of the Broca's area. Epilepsy Behav Case Rep. 2018; 9:42-45. Mnatsakanyan L, Vadera S, Ingalls CW, Zheng J, Sazgar M, Hsu FP, Lin JJ. PMID: 29692970.
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    31. Length of stay for patients undergoing invasive electrode monitoring with stereoelectroencephalography and subdural grids correlates positively with increased institutional profitability. Epilepsia. 2017 06; 58(6):1023-1026. Chan AY, Kharrat S, Lundeen K, Mnatsakanyan L, Sazgar M, Sen-Gupta I, Lin JJ, Hsu FPK, Vadera S. PMID: 28426130.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Amygdala-hippocampal dynamics during salient information processing. Nat Commun. 2017 02 08; 8:14413. Zheng J, Anderson KL, Leal SL, Shestyuk A, Gulsen G, Mnatsakanyan L, Vadera S, Hsu FP, Yassa MA, Knight RT, Lin JJ. PMID: 28176756.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    33. Beta Blockade and Clinical Outcomes in Aneurysmal Subarachnoid Hemorrhage. Open Neurol J. 2016; 10:155-163. Chang MM, Raval RN, Southerland JJ, Adewumi DA, Bahjri KA, Samuel RK, Woods RO, Ajayi OO, Lee BS, Hsu FP, Applegate Ii RL, Dorotta IR. PMID: 28217182.
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    34. Stereotactic robot-assisted MRI-guided laser thermal ablation of radiation necrosis in the posterior cranial fossa: technical note. Neurosurg Focus. 2016 Oct; 41(4):E5. Chan AY, Tran DK, Gill AS, Hsu FP, Vadera S. PMID: 27690660.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    35. Comparison of decoding resolution of standard and high-density electrocorticogram electrodes. J Neural Eng. 2016 Apr; 13(2):026016. Wang PT, King CE, McCrimmon CM, Lin JJ, Sazgar M, Hsu FP, Shaw SJ, Millet DE, Chui LA, Liu CY, Do AH, Nenadic Z. PMID: 26859341.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    36. Frameless Stereotactic Robot-Assisted Subthalamic Nucleus Deep Brain Stimulation: Case Report. World Neurosurg. 2017 Jan; 97:762.e11-762.e14. Vadera S, Chan A, Lo T, Gill A, Morenkova A, Phielipp NM, Hermanowicz N, Hsu FP. PMID: 26585721.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    37. Spinal cord stimulation for treatment of the pain associated with hereditary multiple osteochondromas. J Pain Res. 2015; 8:557-60. Mirpuri RG, Brammeier J, Chen H, Hsu FP, Chiu VK, Chang EY. PMID: 26316806.
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    38. Hoffmann sign: clinical correlation of neurological imaging findings in the cervical spine and brain. Spine (Phila Pa 1976). 2015 Apr 01; 40(7):475-9. Grijalva RA, Hsu FP, Wycliffe ND, Tsao BE, Williams P, Akpolat YT, Cheng WK. PMID: 25608244.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    39. Timing of surgery and bevacizumab therapy in neurosurgical patients with recurrent high grade glioma. J Clin Neurosci. 2015 Jan; 22(1):35-9. Abrams DA, Hanson JA, Brown JM, Hsu FP, Delashaw JB, Bota DA. PMID: 25481268.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    40. Deep brain stimulation for the treatment of childhood dystonic cerebral palsy. J Neurosurg Pediatr. 2014 Dec; 14(6):585-93. Keen JR, Przekop A, Olaya JE, Zouros A, Hsu FP. PMID: 25325412.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    41. Extracting kinetic information from human motor cortical signals. Neuroimage. 2014 Nov 01; 101:695-703. Flint RD, Wang PT, Wright ZA, King CE, Krucoff MO, Schuele SU, Rosenow JM, Hsu FP, Liu CY, Lin JJ, Sazgar M, Millett DE, Shaw SJ, Nenadic Z, Do AH, Slutzky MW. PMID: 25094020.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    42. Therapeutic targeting of malignant glioma. Anticancer Agents Med Chem. 2014; 14(8):1075-84. Alexandru-Abrams D, Jadus MR, Hsu FP, Stathopoulos A, Bota DA. PMID: 25175690.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    43. The evolution of the EGFRvIII (rindopepimut) immunotherapy for glioblastoma multiforme patients. Hum Vaccin Immunother. 2014; 10(11):3322-31. Paff M, Alexandru-Abrams D, Hsu FP, Bota DA. PMID: 25625931.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsPHPublic Health
    44. Antivascular endothelial growth factor antibody for treatment of glioblastoma multiforme. Perm J. 2013; 17(4):68-74. Hanson JA, Hsu FP, Jacob AT, Bota DA, Alexandru D. PMID: 24361023.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    45. Sensitivity and specificity of upper extremity movements decoded from electrocorticogram. Conf Proc IEEE Eng Med Biol Soc. 2013; 2013:5618-21. Do AH, Wang PT, King CE, Schombs A, Lin JJ, Sazgar M, Hsu FP, Shaw SJ, Millett DE, Liu CY, Szymanska AA, Chui LA, Nenadic Z. PMID: 24111011.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. Quantitative verification of the keyhole concept: a comparison of area of exposure in the parasellar region via supraorbital keyhole, frontotemporal pterional, and supraorbital approaches. J Neurosurg. 2013 Feb; 118(2):264-9. Cheng CM, Noguchi A, Dogan A, Anderson GJ, Hsu FP, McMenomey SO, Delashaw JB. PMID: 23140145.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    47. Fractionated proton radiotherapy for benign cavernous sinus meningiomas. Int J Radiat Oncol Biol Phys. 2012 Aug 01; 83(5):e633-7. Slater JD, Loredo LN, Chung A, Bush DA, Patyal B, Johnson WD, Hsu FP, Slater JM. PMID: 22768992.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    48. Clinical implications of neuroimaging in stroke. Transl Stroke Res. 2012 Jun; 3(2):178-81. Olaya JE, Keen JR, Hsu FP. PMID: 24323772.
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    49. State of the Art in Cerebral Trauma: A Neurosurgeon's Perspective. Transl Stroke Res. 2011 Dec; 2(4):427-9. Hsu FP, Keen JR. PMID: 24323678.
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    50. Hydrogen is neuroprotective against surgically induced brain injury. Med Gas Res. 2011 May 18; 1(1):7. Eckermann JM, Chen W, Jadhav V, Hsu FP, Colohan AR, Tang J, Zhang JH. PMID: 22146427.
      View in: PubMed   Mentions: 11     Fields:    
    51. Thoracic cord herniation through a dural defect: description of a case and review of the literature. Surg Neurol. 2009 Mar; 71(3):362-6, discussion 366-7. Ghostine S, Baron EM, Perri B, Jacobson P, Morsette D, Hsu FP. PMID: 18207514.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    52. Inhibition of Src tyrosine kinase and effect on outcomes in a new in vivo model of surgically induced brain injury. J Neurosurg. 2007 Apr; 106(4):680-6. Jadhav V, Matchett G, Hsu FP, Zhang JH. PMID: 17432722.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    53. Prospective evaluation of surgical microscope-integrated intraoperative near-infrared indocyanine green videoangiography during aneurysm surgery. J Neurosurg. 2005 Dec; 103(6):982-9. Raabe A, Nakaji P, Beck J, Kim LJ, Hsu FP, Kamerman JD, Seifert V, Spetzler RF. PMID: 16381184.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    54. Supratentorial arteriovenous malformations. Neurosurgery. 2005 Jul; 57(1 Suppl):164-7; discussion 164-7. Clatterbuck RE, Hsu FP, Spetzler RF. PMID: 15987584.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    55. Pedicle screw placement in the thoracic spine: a comparison of image-guided and manual techniques in cadavers. Spine (Phila Pa 1976). 2005 Jun 15; 30(12):E326-31. Hart RA, Hansen BL, Shea M, Hsu F, Anderson GJ. PMID: 15959355.
      View in: PubMed   Mentions: 18     Fields:    
    56. Orbitozygomatic approach to basilar apex aneurysms. Neurosurgery. 2005 Jan; 56(1 Suppl):172-7; discussion 172-7. Hsu FP, Clatterbuck RE, Spetzler RF. PMID: 15799807.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    57. Extended middle fossa approach: quantitative analysis of petroclival exposure and surgical freedom as a function of successive temporal bone removal by using frameless stereotaxy. J Neurosurg. 2004 Apr; 100(4):695-9. Hsu FP, Anderson GJ, Dogan A, Finizio J, Noguchi A, Liu KC, McMenomey SO, Delashaw JB. PMID: 15070125.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    58. An endoscopic curved Kerrison rongeur for spinal stenosis surgery. Minim Invasive Neurosurg. 2002 Dec; 45(4):254-6. Frank EH, Martin J, Hsu FP. PMID: 12494364.
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    59. An endoscopic dural retractor for spinal stenosis surgery. Minim Invasive Neurosurg. 2002 Sep; 45(3):136-8. Frank EH, Hsu FP. PMID: 12353158.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    60. Pain and spasticity after spinal cord injury: mechanisms and treatment. Spine (Phila Pa 1976). 2001 Dec 15; 26(24 Suppl):S146-60. Burchiel KJ, Hsu FP. PMID: 11805622.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    61. Dural sinus thrombosis endovascular therapy. Crit Care Clin. 1999 Oct; 15(4):743-53, vi. Hsu FP, Kuether T, Nesbit G, Barnwell SL. PMID: 10569119.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    62. A novel endoscopic approach to anterior odontoid screw fixation: technical note. Minim Invasive Neurosurg. 1999 Sep; 42(3):142-5. Horgan MA, Hsu FP, Frank EH. PMID: 10535298.
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    63. Cervical radiculopathy secondary to a tortuous vertebral artery. Case illustration. J Neurosurg. 1998 Sep; 89(3):489. Horgan MA, Hsu FP, Frank EH. PMID: 9724129.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    64. Epidural abscess in the cervical spine. Mt Sinai J Med. 1994 Sep; 61(4):357-62. Rigamonti D, Liem L, Wolf AL, Fiandaca MS, Numaguchi Y, Hsu FP, Nussbaum ES. PMID: 7969230.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    65. Dolichoectatic aneurysm of common carotid artery: an animal model with histological correlation. Pathobiology. 1994; 62(1):8-13. Rigamonti D, Saleh J, Liu AM, Hsu FP, Mergner WJ, Humphrey JD. PMID: 8031476.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
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