Gulsen, Gultekin

TitleAssociate Professor
InstitutionUniversity of California, Irvine
DepartmentRadiological Sciences
Address1001 Health Sciences Road
CA 92697-3950
Phone(949) 824-6557
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    Collapse Research 
    Collapse Research Activities and Funding
    Turn the heat on: High resolution fluorescence imaging via temperature modulation
    NIH/NCI R21CA191389Jul 1, 2015 - Jun 30, 2017
    Role: Principal Investigator
    Fluorescence Tomography in Small Animal Imaging using an Ultra-fast RTE S olver
    NIH/NIBIB R21EB013387Jul 15, 2011 - Jun 30, 2015
    Role: Co-Principal Investigator
    Tomographic Molecular Imaging for Breast Cancer
    NIH/NIBIB R01EB008716Sep 5, 2008 - Jun 30, 2014
    Role: Principal Investigator
    Development of A Multi-Modality System for Onco-Imaging
    NIH/NCI R33CA120175Aug 1, 2007 - Jul 31, 2013
    Role: Principal Investigator
    Development of A Multi-Modality System for Onco-Imaging
    NIH/NCI R21CA120175Aug 1, 2007 - Jul 31, 2008
    Role: Principal Investigator
    Polarization Sensitive OCT for Detection of Melanoma
    NIH/NCI R21CA097304Jul 1, 2002 - Jun 30, 2005
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Jang H, Lim G, Hong KS, Cho J, Gulsen G, Kim CS. Effect of Shot Noise on Simultaneous Sensing in Frequency Division Multiplexed Diffuse Optical Tomographic Imaging Process. Sensors (Basel). 2017 Nov 28; 17(12). PMID: 29182570.
      View in: PubMed
    2. Luk A, Nouizi F, Erkol H, Unlu MB, Gulsen G. Ex vivo validation of photo-magnetic imaging. Opt Lett. 2017 Oct 15; 42(20):4171-4174. PMID: 29028040.
      View in: PubMed
    3. Kwong TC, Nouizi F, Cho J, Lin Y, Sampathkumaran U, Gulsen G. Feasibility study of high spatial resolution multimodality fluorescence tomography in ex vivo biological tissue. Appl Opt. 2017 Oct 01; 56(28):7886-7891. PMID: 29047774.
      View in: PubMed
    4. Ruiz J, Nouizi F, Cho J, Zheng J, Li Y, Chen JH, Su MY, Gulsen G. Breast density quantification using structured-light-based diffuse optical tomography simulations. Appl Opt. 2017 Sep 01; 56(25):7146-7157. PMID: 29047975.
      View in: PubMed
    5. Kipergil EA, Erkol H, Kaya S, Gulsen G, Unlu MB. An analysis of beam parameters on proton-acoustic waves through an analytic approach. Phys Med Biol. 2017 Jun 21; 62(12):4694-4710. PMID: 28252450.
      View in: PubMed
    6. Zheng J, Anderson KL, Leal SL, Shestyuk A, Gulsen G, Mnatsakanyan L, Vadera S, Hsu FP, Yassa MA, Knight RT, Lin JJ. Amygdala-hippocampal dynamics during salient information processing. Nat Commun. 2017 Feb 08; 8:14413. PMID: 28176756.
      View in: PubMed
    7. Kwong TC, Nouizi F, Lin Y, Cho J, Zhu Y, Sampathkumaran U, Gulsen G. Experimental evaluation of the resolution and quantitative accuracy of temperature-modulated fluorescence tomography. Appl Opt. 2017 Jan 20; 56(3):521-529. PMID: 28157909.
      View in: PubMed
    8. Nouizi F, Erkol H, Luk A, Unlu MB, Gulsen G. Real-time photo-magnetic imaging. Biomed Opt Express. 2016 Oct 01; 7(10):3899-3904. PMID: 27867701.
      View in: PubMed
    9. Kwong TC, Hsing M, Lin Y, Thayer D, Unlu MB, Su MY, Gulsen G. Differentiation of tumor vasculature heterogeneity levels in small animals based on total hemoglobin concentration using magnetic resonance-guided diffuse optical tomography in vivo. Appl Opt. 2016 Jul 20; 55(21):5479-87. PMID: 27463894.
      View in: PubMed
    10. Nouizi F, Luk A, Thayer D, Lin Y, Ha S, Gulsen G. Experimental validation of a high-resolution diffuse optical imaging modality: photomagnetic imaging. J Biomed Opt. 2016 Jan; 21(1):16009. PMID: 26790644; PMCID: PMC4719037 [Available on 01/20/17].
    11. Chen JH, Gulsen G, Su MY. Imaging Breast Density: Established and Emerging Modalities. Transl Oncol. 2015 Dec; 8(6):435-45. PMID: 26692524; PMCID: PMC4700291.
    12. Erkol H, Nouizi F, Luk A, Unlu MB, Gulsen G. Comprehensive analytical model for CW laser induced heat in turbid media. Opt Express. 2015 Nov 30; 23(24):31069-84. PMID: 26698736; PMCID: PMC4692257 [Available on 11/19/16].
    13. Nouizi F, Kwong TC, Cho J, Lin Y, Sampathkumaran U, Gulsen G. Implementation of a new scanning method for high-resolution fluorescence tomography using thermo-sensitive fluorescent agents. Opt Lett. 2015 Nov 01; 40(21):4991-4. PMID: 26512501; PMCID: PMC4890556.
    14. Lin Y, Nouizi F, Kwong TC, Gulsen G. Simulation-based evaluation of the resolution and quantitative accuracy of temperature-modulated fluorescence tomography. Appl Opt. 2015 Sep 01; 54(25):7612-21. PMID: 26368884; PMCID: PMC4896397.
    15. Luk AT, Ha S, Nouizi F, Thayer D, Lin Y, Gulsen G. A True Multi-modality Approach for High Resolution Optical Imaging: Photo-Magnetic Imaging. Proc SPIE Int Soc Opt Eng. 2014 Feb 19; 8937. PMID: 25767691.
      View in: PubMed
    16. Lin Y, Gao H, Thayer D, Luk AL, Gulsen G. Photo-magnetic imaging: resolving optical contrast at MRI resolution. Phys Med Biol. 2013 Jun 07; 58(11):3551-62. PMID: 23640084; PMCID: PMC4031318.
    17. Lin Y, Ghijsen M, Nalcioglu O, Gulsen G. In vivo validation of quantitative frequency domain fluorescence tomography. J Biomed Opt. 2012 Dec; 17(12):126021. PMID: 23323291; PMCID: PMC3525318.
    18. Thayer DA, Lin Y, Luk A, Gulsen G. Laser-induced photo-thermal magnetic imaging. Appl Phys Lett. 2012 Aug 20; 101(8):83703. PMID: 22991481.
      View in: PubMed
    19. Lin Y, Kwong TC, Bolisay L, Gulsen G. Temperature-modulated fluorescence tomography based on both concentration and lifetime contrast. J Biomed Opt. 2012 May; 17(5):056007. PMID: 22612130; PMCID: PMC3381013.
    20. Yan H, Lin Y, Barber WC, Unlu MB, Gulsen G. A gantry-based tri-modality system for bioluminescence tomography. Rev Sci Instrum. 2012 Apr; 83(4):043708. PMID: 22559540; PMCID: PMC3350538.
    21. Lin Y, Bolisay L, Ghijsen M, Kwong TC, Gulsen G. Temperature-modulated fluorescence tomography in a turbid media. Appl Phys Lett. 2012 Feb 13; 100(7):73702-737024. PMID: 22393266.
      View in: PubMed
    22. Liu J, Esmailpour T, Shang X, Gulsen G, Liu A, Huang T. TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model. BMC Dev Biol. 2011 Oct 31; 11:65. PMID: 22039763; PMCID: PMC3217876.
    23. Lin Y, Thayer D, Nalcioglu O, Gulsen G. Tumor characterization in small animals using magnetic resonance-guided dynamic contrast enhanced diffuse optical tomography. J Biomed Opt. 2011 Oct; 16(10):106015. PMID: 22029362; PMCID: PMC3221711.
    24. Ghijsen M, Lin Y, Hsing M, Nalcioglu O, Gulsen G. Optimal analysis method for dynamic contrast-enhanced diffuse optical tomography. Int J Biomed Imaging. 2011; 2011:426503. PMID: 21811492; PMCID: PMC3147123.
    25. Lin Y, Barber WC, Iwanczyk JS, Roeck WW, Nalcioglu O, Gulsen G. Quantitative fluorescence tomography using a trimodality system: in vivo validation. J Biomed Opt. 2010 Jul-Aug; 15(4):040503. PMID: 20799770; PMCID: PMC2937044.
    26. Gao H, Lin Y, Gulsen G, Zhao H. Fully linear reconstruction method for fluorescence yield and lifetime through inverse complex-source formulation: simulation studies. Opt Lett. 2010 Jun 01; 35(11):1899-901. PMID: 20517455; PMCID: PMC4343540.
    27. Lin Y, Barber WC, Iwanczyk JS, Roeck W, Nalcioglu O, Gulsen G. Quantitative fluorescence tomography using a combined tri-modality FT/DOT/XCT system. Opt Express. 2010 Apr 12; 18(8):7835-50. PMID: 20588625; PMCID: PMC2898749.
    28. Thayer D, Unlu MB, Lin Y, Yan K, Nalcioglu O, Gulsen G. Dual-contrast dynamic MRI-DOT for small animal imaging. Technol Cancer Res Treat. 2010 Feb; 9(1):61-70. PMID: 20082531; PMCID: PMC3961473.
    29. Unlu MB, Lin Y, Gulsen G. Dynamic contrast-enhanced diffuse optical tomography (DCE-DOT): experimental validation with a dynamic phantom. Phys Med Biol. 2009 Nov 07; 54(21):6739-55. PMID: 19841515; PMCID: PMC3919674.
    30. Lin Y, Yan H, Nalcioglu O, Gulsen G. Quantitative fluorescence tomography with functional and structural a priori information. Appl Opt. 2009 Mar 01; 48(7):1328-36. PMID: 19252634; PMCID: PMC2737514.
    31. Unlu MB, Lin Y, Birgul O, Nalcioglu O, Gulsen G. Simultaneous in vivo dynamic magnetic resonance-diffuse optical tomography for small animal imaging. J Biomed Opt. 2008 Nov-Dec; 13(6):060501. PMID: 19123642; PMCID: PMC2943837.
    32. Unlu MB, Birgul O, Gulsen G. A simulation study of the variability of indocyanine green kinetics and using structural a priori information in dynamic contrast enhanced diffuse optical tomography (DCE-DOT). Phys Med Biol. 2008 Jun 21; 53(12):3189-200. PMID: 18506072; PMCID: PMC2650430.
    33. Burcin Unlu M, Gulsen G. Effects of the time dependence of a bioluminescent source on the tomographic reconstruction. Appl Opt. 2008 Feb 20; 47(6):799-806. PMID: 18288229.
      View in: PubMed
    34. Burcin Unlu M, Birgul O, Shafiiha R, Gulsen G, Nalcioglu O. Diffuse optical tomographic reconstruction using multifrequency data. J Biomed Opt. 2006 Sep-Oct; 11(5):054008. PMID: 17092157.
      View in: PubMed
    35. Gulsen G, Birgul O, Unlu MB, Shafiiha R, Nalcioglu O. Combined diffuse optical tomography (DOT) and MRI system for cancer imaging in small animals. Technol Cancer Res Treat. 2006 Aug; 5(4):351-63. PMID: 16866566.
      View in: PubMed
    36. Gulsen G, Xiong B, Birgul O, Nalcioglu O. Design and implementation of a multifrequency near-infrared diffuse optical tomography system. J Biomed Opt. 2006 Jan-Feb; 11(1):014020. PMID: 16526897.
      View in: PubMed
    37. Cuccia DJ, Bevilacqua F, Durkin AJ, Merritt S, Tromberg BJ, Gulsen G, Yu H, Wang J, Nalcioglu O. In vivo quantification of optical contrast agent dynamics in rat tumors by use of diffuse optical spectroscopy with magnetic resonance imaging coregistration. Appl Opt. 2003 Jun 01; 42(16):2940-50. PMID: 12790443.
      View in: PubMed
    38. Merritt S, Bevilacqua F, Durkin AJ, Cuccia DJ, Lanning R, Tromberg BJ, Gulsen G, Yu H, Wang J, Nalcioglu O. Coregistration of diffuse optical spectroscopy and magnetic resonance imaging in a rat tumor model. Appl Opt. 2003 Jun 01; 42(16):2951-9. PMID: 12790444.
      View in: PubMed
    39. Gulsen G, Yu H, Wang J, Nalcioglu O, Merritt S, Bevilacqua F, Durkin AJ, Cuccia DJ, Lanning R, Tromberg BJ. Congruent MRI and near-infrared spectroscopy for functional and structural imaging of tumors. Technol Cancer Res Treat. 2002 Dec; 1(6):497-505. PMID: 12625777.
      View in: PubMed
    40. Gulsen G, Muftuler LT, Nalcioglu O. A double end-cap birdcage RF coil for small animal whole body imaging. J Magn Reson. 2002 Jun; 156(2):309-12. PMID: 12165267.
      View in: PubMed
    41. Muftuler LT, Gulsen G, Sezen KD, Nalcioglu O. Automatic tuned MRI RF coil for multinuclear imaging of small animals at 3T. J Magn Reson. 2002 Mar; 155(1):39-44. PMID: 11945031.
      View in: PubMed
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