Daniela A Bota

Title(s)Professor, Neurology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-7214
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Targeting p38/JNK MAPK to ameliorate cisplatin-induced adverse sequelae on the nervous system
    NIH R01CA263806Jul 1, 2021 - Jun 30, 2026
    Role: Principal Investigator
    Targeting of Mitochondrial Lon Protease as a Novel Therapy for Glioblastoma
    NIH R01NS109423Sep 1, 2020 - May 31, 2025
    Role: Principal Investigator
    Mechanisms of Chemotherapy Induced Cognitive Defects
    NIH K08NS072234Aug 15, 2011 - Mar 31, 2017
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cisplatin induces BDNF downregulation in middle-aged female rat model while BDNF enhancement attenuates cisplatin neurotoxicity. Exp Neurol. 2024 Feb 07; 114717. Lomeli N, Pearre DC, Cruz M, Di K, Ricks-Oddie JL, Bota DA. PMID: 38336286.
      View in: PubMed   Mentions:    Fields:    
    2. BRAF-MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas. N Engl J Med. 2023 Jul 13; 389(2):118-126. Brastianos PK, Twohy E, Geyer S, Gerstner ER, Kaufmann TJ, Tabrizi S, Kabat B, Thierauf J, Ruff MW, Bota DA, Reardon DA, Cohen AL, De La Fuente MI, Lesser GJ, Campian J, Agarwalla PK, Kumthekar P, Mann B, Vora S, Knopp M, Iafrate AJ, Curry WT, Cahill DP, Shih HA, Brown PD, Santagata S, Barker FG, Galanis E. PMID: 37437144; PMCID: PMC10464854.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    3. Cisplatin Induces BDNF Downregulation in Middle-Aged Female Rat Model while BDNF Enhancement Attenuates Cisplatin Neurotoxicity. bioRxiv. 2023 May 17. Lomeli N, Pearre DC, Cruz M, Di K, Bota DA. PMID: 37293048; PMCID: PMC10245559.
      View in: PubMed   Mentions:
    4. Identification of new hit to lead magmas inhibitors as potential therapeutics for glioblastoma. Bioorg Med Chem Lett. 2023 07 15; 91:129330. Das BC, Lepe JJ, Adil Shareef M, Lomeli N, Das S, Bota DA. PMID: 37201660; PMCID: PMC10506439.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. LonP1 Drives Proneural Mesenchymal Transition in IDH1-R132H Diffuse Glioma. bioRxiv. 2023 Apr 17. Douglas C, Lomeli N, Vu T, Pham J, Bota DA. PMID: 37131765; PMCID: PMC10153221.
      View in: PubMed   Mentions:
    6. Discovery and Validation of Novel LonP1 and Proteasome Inhibitor in IDH1-R132H Malignant Astrocytoma Models. bioRxiv. 2023 Apr 17. Douglas C, Lomeli N, Lepe J, Di K, Nandwana NK, Vu T, Pham J, Kenney MC, Das B, Bota DA. PMID: 37131786; PMCID: PMC10153114.
      View in: PubMed   Mentions:
    7. Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial. JAMA Oncol. 2023 01 01; 9(1):112-121. Liau LM, Ashkan K, Brem S, Campian JL, Trusheim JE, Iwamoto FM, Tran DD, Ansstas G, Cobbs CS, Heth JA, Salacz ME, D'Andre S, Aiken RD, Moshel YA, Nam JY, Pillainayagam CP, Wagner SA, Walter KA, Chaudhary R, Goldlust SA, Lee IY, Bota DA, Elinzano H, Grewal J, Lillehei K, Mikkelsen T, Walbert T, Abram S, Brenner AJ, Ewend MG, Khagi S, Lovick DS, Portnow J, Kim L, Loudon WG, Martinez NL, Thompson RC, Avigan DE, Fink KL, Geoffroy FJ, Giglio P, Gligich O, Krex D, Lindhorst SM, Lutzky J, Meisel HJ, Nadji-Ohl M, Sanchin L, Sloan A, Taylor LP, Wu JK, Dunbar EM, Etame AB, Kesari S, Mathieu D, Piccioni DE, Baskin DS, Lacroix M, May SA, New PZ, Pluard TJ, Toms SA, Tse V, Peak S, Villano JL, Battiste JD, Mulholland PJ, Pearlman ML, Petrecca K, Schulder M, Prins RM, Boynton AL, Bosch ML. PMID: 36394838; PMCID: PMC9673026.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCellsPHPublic Health
    8. Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment. J Exp Clin Cancer Res. 2022 Dec 14; 41(1):344. Bota DA, Taylor TH, Piccioni DE, Duma CM, LaRocca RV, Kesari S, Carrillo JA, Abedi M, Aiken RD, Hsu FPK, Kong XT, Hsieh C, Bota PG, Nistor GI, Keirstead HS, Dillman RO. PMID: 36517865; PMCID: PMC9749349.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsCTClinical Trials
    9. Non-viral precision T cell receptor replacement for personalized cell therapy. Nature. 2023 03; 615(7953):687-696. Foy SP, Jacoby K, Bota DA, Hunter T, Pan Z, Stawiski E, Ma Y, Lu W, Peng S, Wang CL, Yuen B, Dalmas O, Heeringa K, Sennino B, Conroy A, Bethune MT, Mende I, White W, Kukreja M, Gunturu S, Humphrey E, Hussaini A, An D, Litterman AJ, Quach BB, Ng AHC, Lu Y, Smith C, Campbell KM, Anaya D, Skrdlant L, Huang EY, Mendoza V, Mathur J, Dengler L, Purandare B, Moot R, Yi MC, Funke R, Sibley A, Stallings-Schmitt T, Oh DY, Chmielowski B, Abedi M, Yuan Y, Sosman JA, Lee SM, Schoenfeld AJ, Baltimore D, Heath JR, Franzusoff A, Ribas A, Rao AV, Mandl SJ. PMID: 36356599; PMCID: PMC9768791.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCellsCTClinical Trials
    10. Adherence to Prophylactic Anticonvulsant Guidelines for Newly Diagnosed Brain Tumor Patients: A Quality Improvement Study. J Adv Pract Oncol. 2022 Nov; 13(8):775-789. Fu DB, Kong XT, Veenema TG, Bota DA, Koirala B. PMID: 36727021; PMCID: PMC9881735.
      View in: PubMed   Mentions:
    11. A digital approach to asthma self-management in adults: Protocol for a pragmatic randomized controlled trial. Contemp Clin Trials. 2022 Nov; 122:106902. Silberman J, Sarlati S, Harris B, Bokhari W, Boushey H, Chesnutt A, Zhu P, Sitts K, Taylor TH, Willey VJ, Fuentes E, LeKrey M, Hou E, Kaur M, Niyonkuru C, Muscioni G, Bianchi MT, Bota DA, Lee RA. PMID: 36049674.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    12. Somatostatin analogues in treatment-refractory meningioma: a systematic review with meta-analysis of individual patient data. Neurosurg Rev. 2022 Oct; 45(5):3067-3081. Jensen LR, Maier AD, Lomstein A, Graillon T, Hrachova M, Bota D, Ruiz-Patiño A, Arrieta O, Cardona AF, Rudà R, Furtner J, Roeckle U, Clement P, Preusser M, Scheie D, Broholm H, Kristensen BW, Skjøth-Rasmussen J, Ziebell M, Munch TN, Fugleholm K, Walter MA, Mathiesen T, Mirian C. PMID: 35984552.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. A Prospective, Cohort Study of SITOIGANAP to Treat Glioblastoma When Given in Combination With Granulocyte-Macrophage Colony-Stimulating Factor/Cyclophosphamide/Bevacizumab/Nivolumab or Granulocyte-Macrophage Colony-Stimulating Factor/Cyclophosphamide/Bevacizumab/Pembrolizumab in Patients Who Failed Prior Treatment With Surgical Resection, Radiation, and Temozolomide. Front Oncol. 2022; 12:934638. Bota DA, Taylor TH, Lomeli N, Kong XT, Fu BD, Schönthal AH, Singer S, Blumenthal DT, Senecal FM, Linardou H, Rokas E, Antoniou DG, Schijns VEJC, Chen TC, Elliot J, Stathopoulos A. PMID: 35837107; PMCID: PMC9273968.
      View in: PubMed   Mentions: 1  
    14. Successful Consolidation/Maintenance Therapy with Single Agent Ibrutinib for Primary CNS Lymphoma after Initial Induction Therapy. Neurol Int. 2022 Jun 27; 14(3):574-580. Du S, Bota D, Kong XT. PMID: 35893281; PMCID: PMC9326764.
      View in: PubMed   Mentions:
    15. Altered Retrograde Signaling Patterns in Breast Cancer Cells Cybrids with H and J Mitochondrial DNA Haplogroups. Int J Mol Sci. 2022 Jun 15; 23(12). Chang S, Singh L, Thaker K, Abedi S, Singh MK, Patel TH, Chwa M, Atilano SR, Udar N, Bota D, Kenney MC. PMID: 35743133; PMCID: PMC9224519.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    16. COVID-19 vaccination elicits an evolving, cross-reactive antibody response to epitopes conserved with endemic coronavirus spike proteins. Cell Rep. 2022 07 05; 40(1):111022. Elko EA, Nelson GA, Mead HL, Kelley EJ, Carvalho ST, Sarbo NG, Harms CE, Le Verche V, Cardoso AA, Ely JL, Boyle AS, Piña A, Henson SN, Rahee F, Keim PS, Celona KR, Yi J, Settles EW, Bota DA, Yu GC, Morris SR, Zaia JA, Ladner JT, Altin JA. PMID: 35753310; PMCID: PMC9188999.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsPHPublic Health
    17. Feasibility of Cognitive Training to Promote Recovery in Cancer-Related Cognitive Impairment in Adolescent and Young Adult Patients. J Adolesc Young Adult Oncol. 2022 06; 11(3):290-296. Gooch M, Mehta A, John T, Lomeli N, Naeem E, Mucci G, Toh YL, Chan A, Bota DA, Torno L. PMID: 34672806; PMCID: PMC9464087.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Marizomib alone or in combination with bevacizumab in patients with recurrent glioblastoma: Phase I/II clinical trial data. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab142. Bota DA, Mason W, Kesari S, Magge R, Winograd B, Elias I, Reich SD, Levin N, Trikha M, Desjardins A. PMID: 34729484; PMCID: PMC8557653.
      View in: PubMed   Mentions: 14  
    19. Exploring the role and clinical implications of proteasome inhibition in medulloblastoma. Pediatr Blood Cancer. 2021 10; 68(10):e29168. Hoerig CM, Plant-Fox AS, Pulley MD, Di K, Bota DA. PMID: 34114315; PMCID: PMC10516099.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Cognitive complications of cancer and cancer-related treatments - Novel paradigms. Neurosci Lett. 2021 04 01; 749:135720. Lomeli N, Lepe J, Gupta K, Bota DA. PMID: 33582187; PMCID: PMC8423125.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    21. Development and external validation of a prognostic tool for COVID-19 critical disease. PLoS One. 2020; 15(12):e0242953. Chow DS, Glavis-Bloom J, Soun JE, Weinberg B, Loveless TB, Xie X, Mutasa S, Monuki E, Park JI, Bota D, Wu J, Thompson L, Boden-Albala B, Khan S, Amin AN, Chang PD. PMID: 33296357; PMCID: PMC7725393.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    22. Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Glioma: A Randomized Clinical Trial. JAMA Oncol. 2020 12 01; 6(12):1939-1946. Cloughesy TF, Petrecca K, Walbert T, Butowski N, Salacz M, Perry J, Damek D, Bota D, Bettegowda C, Zhu JJ, Iwamoto F, Placantonakis D, Kim L, Elder B, Kaptain G, Cachia D, Moshel Y, Brem S, Piccioni D, Landolfi J, Chen CC, Gruber H, Rao AR, Hogan D, Accomando W, Ostertag D, Montellano TT, Kheoh T, Kabbinavar F, Vogelbaum MA. PMID: 33119048; PMCID: PMC7596685.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    23. Differential effects of cisplatin on cybrid cells with varying mitochondrial DNA haplogroups. PeerJ. 2020; 8:e9908. Abedi S, Yung G, Atilano SR, Thaker K, Chang S, Chwa M, Schneider K, Udar N, Bota D, Kenney MC. PMID: 33062421; PMCID: PMC7533064.
      View in: PubMed   Mentions: 6     Fields:    
    24. Planning for post-pandemic cancer care delivery: Recovery or opportunity for redesign? CA Cancer J Clin. 2021 01; 71(1):34-46. Cinar P, Bold R, Bosslet BA, Bota DA, Burgess D, Chew HK, Cohen JG, Elquza E, Gold KA, Kamiya E, Karlan BY, McKay RR, Patel SP, Ternavan K, Welborn J, Yamamoto M, Rugo HS. PMID: 32997807; PMCID: PMC7537198.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    25. Somatostatin Receptor-Targeted Radiopeptide Therapy in Treatment-Refractory Meningioma: Individual Patient Data Meta-analysis. J Nucl Med. 2021 04; 62(4):507-513. Mirian C, Duun-Henriksen AK, Maier A, Pedersen MM, Jensen LR, Bashir A, Graillon T, Hrachova M, Bota D, van Essen M, Spanjol P, Kreis C, Law I, Broholm H, Poulsgaard L, Fugleholm K, Ziebell M, Munch T, Walter MA, Mathiesen T. PMID: 32859705.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    26. A Retrospective Interventional Cohort Study to Assess the Safety and Efficacy of Sandostatin LAR for Treatment of Recurrent and/or Refractory Meningiomas. Front Neurol. 2020; 11:373. Hrachova M, Nguyen ENT, Fu BD, Dandekar MJ, Kong XT, Cadena G, Hsu FPK, Billimek J, Taylor TH, Bota DA. PMID: 32435228; PMCID: PMC7218113.
      View in: PubMed   Mentions: 6  
    27. Elevations in High-Sensitive Cardiac Troponin T and N-Terminal Prohormone Brain Natriuretic Peptide Levels in the Serum Can Predict the Development of Anthracycline-Induced Cardiomyopathy. Am J Ther. 2020 Mar/Apr; 27(2):e142-e150. Bisoc A, Ciurescu D, Radoi M, Tântu MM, Rogozea L, Sweidan AJ, Bota DA. PMID: 30648987.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    28. Mitochondrial-associated impairments of temozolomide on neural stem/progenitor cells and hippocampal neurons. Mitochondrion. 2020 05; 52:56-66. Lomeli N, Di K, Pearre DC, Chung TF, Bota DA. PMID: 32045717; PMCID: PMC7415494.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    29. Rindopepimut with Bevacizumab for Patients with Relapsed EGFRvIII-Expressing Glioblastoma (ReACT): Results of a Double-Blind Randomized Phase II Trial. Clin Cancer Res. 2020 04 01; 26(7):1586-1594. Reardon DA, Desjardins A, Vredenburgh JJ, O'Rourke DM, Tran DD, Fink KL, Nabors LB, Li G, Bota DA, Lukas RV, Ashby LS, Duic JP, Mrugala MM, Cruickshank S, Vitale L, He Y, Green JA, Yellin MJ, Turner CD, Keler T, Davis TA, Sampson JH, ReACT trial investigators. PMID: 32034072.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    30. European mtDNA Variants Are Associated With Differential Responses to Cisplatin, an Anticancer Drug: Implications for Drug Resistance and Side Effects. Front Oncol. 2019; 9:640. Patel TH, Norman L, Chang S, Abedi S, Liu C, Chwa M, Atilano SR, Thaker K, Lu S, Jazwinski SM, Miceli MV, Udar N, Bota D, Kenney MC. PMID: 31380278; PMCID: PMC6659439.
      View in: PubMed   Mentions: 17  
    31. Optimizing Neuro-Oncology Imaging: A Review of Deep Learning Approaches for Glioma Imaging. Cancers (Basel). 2019 Jun 14; 11(6). Shaver MM, Kohanteb PA, Chiou C, Bardis MD, Chantaduly C, Bota D, Filippi CG, Weinberg B, Grinband J, Chow DS, Chang PD. PMID: 31207930; PMCID: PMC6627902.
      View in: PubMed   Mentions: 33  
    32. Magmas inhibition as a potential treatment strategy in malignant glioma. J Neurooncol. 2019 Jan; 141(2):267-276. Di K, Lomeli N, Bota DA, Das BC. PMID: 30414099; PMCID: PMC6474352.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    33. Somatic SMARCB1 Mutation in Sporadic Multiple Meningiomas: Case Report. Front Neurol. 2018; 9:919. Wang AS, Jamshidi AO, Oh N, Sahyouni R, Nowroozizadeh B, Kim R, Hsu FPK, Bota D. PMID: 30416484; PMCID: PMC6212508.
      View in: PubMed   Mentions: 3  
    34. Therapeutic Immunization against Glioblastoma. Int J Mol Sci. 2018 Aug 27; 19(9). Schijns VEJC, Pretto C, Strik AM, Gloudemans-Rijkers R, Deviller L, Pierre D, Chung J, Dandekar M, Carrillo JA, Kong XT, Fu BD, Hsu FPK, Hofman FM, Chen TC, Zidovetzki R, Bota DA, Stathopoulos A. PMID: 30150597; PMCID: PMC6163986.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    35. Management of low-grade glioma: a systematic review and meta-analysis. Neurooncol Pract. 2019 Jul; 6(4):249-258. Brown TJ, Bota DA, van Den Bent MJ, Brown PD, Maher E, Aregawi D, Liau LM, Buckner JC, Weller M, Berger MS, Glantz M. PMID: 31386075; PMCID: PMC6660818.
      View in: PubMed   Mentions: 32  
    36. Mineralocorticoid receptor antagonism improves parenchymal arteriole dilation via a TRPV4-dependent mechanism and prevents cognitive dysfunction in hypertension. Am J Physiol Heart Circ Physiol. 2018 11 01; 315(5):H1304-H1315. Diaz-Otero JM, Yen TC, Fisher C, Bota D, Jackson WF, Dorrance AM. PMID: 30118343; PMCID: PMC6297805.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    37. Phase II study of ERC1671 plus bevacizumab versus bevacizumab plus placebo in recurrent glioblastoma: interim results and correlations with CD4+ T-lymphocyte counts. CNS Oncol. 2018 07 01; 7(3):CNS22. Bota DA, Chung J, Dandekar M, Carrillo JA, Kong XT, Fu BD, Hsu FP, Schönthal AH, Hofman FM, Chen TC, Zidovetzki R, Pretto C, Strik A, Schijns VE, Stathopoulos A. PMID: 30157683; PMCID: PMC6200061.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCellsCTClinical Trials
    38. Correction to: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma. J Transl Med. 2018 06 29; 16(1):179. Liau LM, Ashkan K, Tran DD, Campian JL, Trusheim JE, Cobbs CS, Heth JA, Salacz M, Taylor S, D'Andre SD, Iwamoto FM, Dropcho EJ, Moshel YA, Walter KA, Pillainayagam CP, Aiken R, Chaudhary R, Goldlust SA, Bota DA, Duic P, Grewal J, Elinzano H, Toms SA, Lillehei KO, Mikkelsen T, Walbert T, Abram SR, Brenner AJ, Brem S, Ewend MG, Khagi S, Portnow J, Kim LJ, Loudon WG, Thompson RC, Avigan DE, Fink KL, Geoffroy FJ, Lindhorst S, Lutzky J, Sloan AE, Schackert G, Krex D, Meisel HJ, Wu J, Davis RP, Duma C, Etame AB, Mathieu D, Kesari S, Piccioni D, Westphal M, Baskin DS, New PZ, Lacroix M, May SA, Pluard TJ, Tse V, Green RM, Villano JL, Pearlman M, Petrecca K, Schulder M, Taylor LP, Maida AE, Prins RM, Cloughesy TF, Mulholland P, Bosch ML. PMID: 29958537; PMCID: PMC6026340.
      View in: PubMed   Mentions: 9     Fields:    
    39. CIRM Alpha Stem Cell Clinics: Collaboratively Addressing Regenerative Medicine Challenges. Cell Stem Cell. 2018 06 01; 22(6):801-805. Jamieson CHM, Millan MT, Creasey AA, Lomax G, Donohoe ME, Walters MC, Abedi M, Bota DA, Zaia JA, Adams JS. PMID: 29859170.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    40. First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma. J Transl Med. 2018 05 29; 16(1):142. Liau LM, Ashkan K, Tran DD, Campian JL, Trusheim JE, Cobbs CS, Heth JA, Salacz M, Taylor S, D'Andre SD, Iwamoto FM, Dropcho EJ, Moshel YA, Walter KA, Pillainayagam CP, Aiken R, Chaudhary R, Goldlust SA, Bota DA, Duic P, Grewal J, Elinzano H, Toms SA, Lillehei KO, Mikkelsen T, Walbert T, Abram SR, Brenner AJ, Brem S, Ewend MG, Khagi S, Portnow J, Kim LJ, Loudon WG, Thompson RC, Avigan DE, Fink KL, Geoffroy FJ, Lindhorst S, Lutzky J, Sloan AE, Schackert G, Krex D, Meisel HJ, Wu J, Davis RP, Duma C, Etame AB, Mathieu D, Kesari S, Piccioni D, Westphal M, Baskin DS, New PZ, Lacroix M, May SA, Pluard TJ, Tse V, Green RM, Villano JL, Pearlman M, Petrecca K, Schulder M, Taylor LP, Maida AE, Prins RM, Cloughesy TF, Mulholland P, Bosch ML. PMID: 29843811; PMCID: PMC5975654.
      View in: PubMed   Mentions: 256     Fields:    Translation:HumansCellsCTClinical Trials
    41. Deep-Learning Convolutional Neural Networks Accurately Classify Genetic Mutations in Gliomas. AJNR Am J Neuroradiol. 2018 07; 39(7):1201-1207. Chang P, Grinband J, Weinberg BD, Bardis M, Khy M, Cadena G, Su MY, Cha S, Filippi CG, Bota D, Baldi P, Poisson LM, Jain R, Chow D. PMID: 29748206; PMCID: PMC6880932.
      View in: PubMed   Mentions: 146     Fields:    Translation:HumansCells
    42. Intracranial meningioma with carcinoma tumor-to-tumor metastasis: two case reports. CNS Oncol. 2018 04; 7(2):CNS09. Pham JT, Kim RC, Nguyen A, Bota D, Kong XT, Vadera S, Hsu F, Carrillo JA. PMID: 29698064; PMCID: PMC5977278.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    43. Targeting HSP90 in malignant gliomas: onalespib as a potential therapeutic. Transl Cancer Res. 2018 Apr; 7(4):6215-6226. Lomeli N, Bota DA. PMID: 31840022; PMCID: PMC6910236.
      View in: PubMed   Mentions: 2  
    44. Chemotherapy-related cognitive dysfunction and effects on quality of life in gynecologic cancer patients. Expert Rev Qual Life Cancer Care. 2018; 3(1):19-26. Pearre DC, Bota DA. PMID: 30775449; PMCID: PMC6377208.
      View in: PubMed   Mentions: 4  
    45. Multiscale modeling of glioblastoma. Transl Cancer Res. 2018 Feb; 7(Suppl 1):S96-S98. Yan H, Romero-López M, Benitez LI, Di K, Frieboes HB, Hughes CCW, Bota DA, Lowengrub JS. PMID: 30211018; PMCID: PMC6130886.
      View in: PubMed   Mentions:
    46. Expression of the BRAF L597Q mutation in sporadic neurofibromas of the upper extremity. Exp Mol Pathol. 2017 12; 103(3):276-278. Shaterian A, Bota D, Leis A. PMID: 29162506.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    47. Diminished stress resistance and defective adaptive homeostasis in age-related diseases. Clin Sci (Lond). 2017 Nov 01; 131(21):2573-2599. Lomeli N, Bota DA, Davies KJA. PMID: 29070521.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    48. Imaging Genetic Heterogeneity in Glioblastoma and Other Glial Tumors: Review of Current Methods and Future Directions. AJR Am J Roentgenol. 2018 Jan; 210(1):30-38. Chow D, Chang P, Weinberg BD, Bota DA, Grinband J, Filippi CG. PMID: 28981352.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    49. 3D Mathematical Modeling of Glioblastoma Suggests That Transdifferentiated Vascular Endothelial Cells Mediate Resistance to Current Standard-of-Care Therapy. Cancer Res. 2017 08 01; 77(15):4171-4184. Yan H, Romero-López M, Benitez LI, Di K, Frieboes HB, Hughes CCW, Bota DA, Lowengrub JS. PMID: 28536277; PMCID: PMC5540807.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    50. Cancer-Incidence, prevalence and mortality in the oldest-old. A comprehensive review. Mech Ageing Dev. 2017 06; 164:113-126. Nolen SC, Evans MA, Fischer A, Corrada MM, Kawas CH, Bota DA. PMID: 28502820; PMCID: PMC7788911.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    51. Case of glioblastoma patient treated with tumor treating fields therapy at recurrence degenerating to sarcoma. CNS Oncol. 2017 04; 6(2):89-94. Majd P, O'Connell DE, Kim RC, Bota DA, Carrillo JA. PMID: 28303729; PMCID: PMC6020874.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. First report of tumor treating fields use in combination with bevacizumab in a pediatric patient: a case report. CNS Oncol. 2017 01; 6(1):11-18. O'Connell D, Shen V, Loudon W, Bota DA. PMID: 27918194; PMCID: PMC6027925.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    53. Cisplatin-induced mitochondrial dysfunction is associated with impaired cognitive function in rats. Free Radic Biol Med. 2017 01; 102:274-286. Lomeli N, Di K, Czerniawski J, Guzowski JF, Bota DA. PMID: 27908784; PMCID: PMC5308450.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    54. Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma. Oncotarget. 2016 Nov 22; 7(47):77457-77467. Di K, Lomeli N, Wood SD, Vanderwal CD, Bota DA. PMID: 27764809; PMCID: PMC5340227.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    55. Systemic cisplatin exposure during infancy and adolescence causes impaired cognitive function in adulthood. Behav Brain Res. 2017 02 15; 319:200-206. John T, Lomeli N, Bota DA. PMID: 27851909; PMCID: PMC5332150.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    56. A state-of-the-art review and guidelines for tumor treating fields treatment planning and patient follow-up in glioblastoma. CNS Oncol. 2017 01; 6(1):29-43. Trusheim J, Dunbar E, Battiste J, Iwamoto F, Mohile N, Damek D, Bota DA, Connelly J. PMID: 27628854; PMCID: PMC6027938.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    57. The effects of sequential treatments on hippocampal volumes in malignant glioma patients. J Neurooncol. 2016 09; 129(3):433-441. Nolen SC, Lee B, Shantharam S, Yu HJ, Su L, Billimek J, Bota DA. PMID: 27393350; PMCID: PMC5097045.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    58. Mitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disorders. Free Radic Biol Med. 2016 11; 100:188-198. Bota DA, Davies KJ. PMID: 27387767; PMCID: PMC5183306.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    59. Cognitive Impairment in Survivors of Adolescent and Early Young Adult Onset Non-CNS Cancers: Does Chemotherapy Play a Role? J Adolesc Young Adult Oncol. 2016 09; 5(3):226-31. John TD, Sender LS, Bota DA. PMID: 27078009.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    60. Marizomib activity as a single agent in malignant gliomas: ability to cross the blood-brain barrier. Neuro Oncol. 2016 06; 18(6):840-8. Di K, Lloyd GK, Abraham V, MacLaren A, Burrows FJ, Desjardins A, Trikha M, Bota DA. PMID: 26681765; PMCID: PMC4864261.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    61. First clinical results of a personalized immunotherapeutic vaccine against recurrent, incompletely resected, treatment-resistant glioblastoma multiforme (GBM) tumors, based on combined allo- and auto-immune tumor reactivity. Vaccine. 2015 May 28; 33(23):2690-6. Schijns VE, Pretto C, Devillers L, Pierre D, Hofman FM, Chen TC, Mespouille P, Hantos P, Glorieux P, Bota DA, Stathopoulos A. PMID: 25865468; PMCID: PMC10494870.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsPHPublic HealthCTClinical Trials
    62. Use of ERC-1671 Vaccine in a Patient with Recurrent Glioblastoma Multiforme after Progression during Bevacizumab Therapy: First Published Report. Perm J. 2015; 19(2):41-6. Bota DA, Alexandru-Abrams D, Pretto C, Hofman FM, Chen TC, Fu B, Carrillo JA, Schijns VE, Stathopoulos A. PMID: 25785641; PMCID: PMC4403580.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    63. Timing of surgery and bevacizumab therapy in neurosurgical patients with recurrent high grade glioma. J Clin Neurosci. 2015 Jan; 22(1):35-9. Abrams DA, Hanson JA, Brown JM, Hsu FP, Delashaw JB, Bota DA. PMID: 25481268.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    64. Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models. J Neurooncol. 2014 Dec; 120(3):473-81. Di K, Keir ST, Alexandru-Abrams D, Gong X, Nguyen H, Friedman HS, Bota DA. PMID: 25115740.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    65. Low-doses of cisplatin injure hippocampal synapses: a mechanism for 'chemo' brain? Exp Neurol. 2014 May; 255:137-44. Andres AL, Gong X, Di K, Bota DA. PMID: 24594220; PMCID: PMC4059602.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    66. Special medical conditions associated with catatonia in the internal medicine setting: hyponatremia-inducing psychosis and subsequent catatonia. Perm J. 2014; 18(3):78-81. Novac AA, Bota D, Witkowski J, Lipiz J, Bota RG. PMID: 25102520; PMCID: PMC4116269.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    67. The evolution of the EGFRvIII (rindopepimut) immunotherapy for glioblastoma multiforme patients. Hum Vaccin Immunother. 2014; 10(11):3322-31. Paff M, Alexandru-Abrams D, Hsu FP, Bota DA. PMID: 25625931; PMCID: PMC4514075.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsPHPublic Health
    68. Therapeutic targeting of malignant glioma. Anticancer Agents Med Chem. 2014; 14(8):1075-84. Alexandru-Abrams D, Jadus MR, Hsu FP, Stathopoulos A, Bota DA. PMID: 25175690.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    69. Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis. J Neurosurg. 2013 Dec; 119(6):1415-23. Bota DA, Alexandru D, Keir ST, Bigner D, Vredenburgh J, Friedman HS. PMID: 24093630; PMCID: PMC4550014.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    70. Two Patients With Brain Tumors Who Received Bevacizumab and Radiotherapy: Optic Neuropathy and Quality-of-Life Issues. J Adv Pract Oncol. 2013 Jul; 4(4):252-6. Fu DB, Alexandru D, Curticiu DM, Fu Y, Bota DA. PMID: 25032005; PMCID: PMC4093434.
      View in: PubMed   Mentions: 2  
    71. Retrospective analysis of the tolerability and activity of lacosamide in patients with brain tumors: clinical article. J Neurosurg. 2013 Jun; 118(6):1183-7. Saria MG, Corle C, Hu J, Rudnick JD, Phuphanich S, Mrugala MM, Crew LK, Bota DA, Dan Fu B, Kim RY, Brown T, Feely H, Brechlin J, Brown BD, Drappatz J, Wen PY, Chen CC, Carter B, Lee JW, Kesari S. PMID: 23451905.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansPHPublic Health
    72. Antivascular endothelial growth factor antibody for treatment of glioblastoma multiforme. Perm J. 2013; 17(4):68-74. Hanson JA, Hsu FP, Jacob AT, Bota DA, Alexandru D. PMID: 24361023; PMCID: PMC3854812.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    73. TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth. Oncogene. 2013 Oct 17; 32(42):5038-47. Di K, Linskey ME, Bota DA. PMID: 23178488; PMCID: PMC3766389.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    74. Glioma big potassium channel expression in human cancers and possible T cell epitopes for their immunotherapy. J Immunol. 2012 Sep 01; 189(5):2625-34. Ge L, Hoa NT, Cornforth AN, Bota DA, Mai A, Kim DI, Chiou SK, Hickey MJ, Kruse CA, Jadus MR. PMID: 22844111; PMCID: PMC3496203.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    75. SU-E-J-108: Quantitative Analysis of Longitudinal Cognitive Impairment Due to Radiation Therapy Based on Automatic Segmentation of Hippocampus and Subcortical Structure. Med Phys. 2012 Jun; 39(6Part7):3677. Lin Y, Chang D, Bota D, Roa D, Al-Ghazi M, Yu H, Kuo J, Nie K, Fwu P, Su M. PMID: 28519814.
      View in: PubMed   Mentions:    Fields:    
    76. Epidemiology of central nervous system metastases. Prog Neurol Surg. 2012; 25:13-29. Alexandru D, Bota DA, Linskey ME. PMID: 22236665.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    77. Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy. Neurology. 2011 Nov 29; 77(22):e135; author reply e135-6. Chamberlain MC, Bota DA, Linskey ME, Schwartz PH. PMID: 22123788.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    78. Impairment of lon-induced protection against the accumulation of oxidized proteins in senescent wi-38 fibroblasts. J Gerontol A Biol Sci Med Sci. 2011 Nov; 66(11):1178-85. Ngo JK, Pomatto LC, Bota DA, Koop AL, Davies KJ. PMID: 21868393; PMCID: PMC3193527.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    79. Pulmonary metastases in patients with recurrent, treatment-resistant meningioma: prognosis and identification by ¹¹¹Indium-octreotide imaging. Cancer. 2011 Oct 01; 117(19):4506-11. Alexandru D, Glantz MJ, Kim L, Chamberlain MC, Bota DA. PMID: 21446045.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    80. Immunotherapy of brain cancers: the past, the present, and future directions. Clin Dev Immunol. 2010; 2010:296453. Ge L, Hoa N, Bota DA, Natividad J, Howat A, Jadus MR. PMID: 21437175; PMCID: PMC3061456.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    81. Primary leptomeningeal plasmablastic lymphoma. J Neurooncol. 2011 Sep; 104(3):835-8. Mathews MS, Bota DA, Kim RC, Hasso AN, Linskey ME. PMID: 21359853; PMCID: PMC3171045.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    82. Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy. Neurology. 2011 Mar 29; 76(13):1126-34. Gong X, Schwartz PH, Linskey ME, Bota DA. PMID: 21346220; PMCID: PMC3269770.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    83. The use of patient navigators to improve cancer care for Hispanic patients. Clin Med Insights Oncol. 2011 Feb 02; 5:1-7. Robie L, Alexandru D, Bota DA. PMID: 21339858; PMCID: PMC3040076.
      View in: PubMed   Mentions: 9  
    84. Fos-related antigen-1 (Fra-1) is a regulator of glioma cell malignant phenotype. Cancer Biol Ther. 2011 Feb 01; 11(3):307-10. Kesari S, Bota DA. PMID: 21242721.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    85. Secondary fibrosarcoma of the brain stem treated with cyclophosphamide and Imatinib. J Neurooncol. 2010 Aug; 99(1):123-8. Alexandru D, Van Horn DK, Bota DA. PMID: 20043189; PMCID: PMC2895888.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    86. Acute methotrexate neurotoxicity with choreiform movements and focal neurological deficits: a case report. South Med J. 2009 Oct; 102(10):1071-4. Bota DA, Dafer RM. PMID: 19738521.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    87. Toward a better identification and treatment of schizophrenia prodrome. Bull Menninger Clin. 2008; 72(3):210-27. Bota RG, Sagduyu K, Filin EE, Bota DA, Munro S. PMID: 18990056.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    88. Interstitial chemotherapy with biodegradable BCNU (Gliadel) wafers in the treatment of malignant gliomas. Ther Clin Risk Manag. 2007 Oct; 3(5):707-15. Bota DA, Desjardins A, Quinn JA, Affronti ML, Friedman HS. PMID: 18472995; PMCID: PMC2376068.
      View in: PubMed   Mentions: 40  
    89. The dynamics of insight in the prodrome of schizophrenia. CNS Spectr. 2006 May; 11(5):355-62. Bota RG, Munro JS, Ricci WF, Bota DA. PMID: 16641840.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    90. Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radic Biol Med. 2005 Mar 01; 38(5):665-77. Bota DA, Ngo JK, Davies KJ. PMID: 15683722.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    91. Protein degradation in mitochondria: implications for oxidative stress, aging and disease: a novel etiological classification of mitochondrial proteolytic disorders. Mitochondrion. 2001 Jun; 1(1):33-49. Bota DA, Davies KJ. PMID: 16120267.
      View in: PubMed   Mentions: 31     Fields:    
    92. Cutting edge: identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine. J Immunol. 2000 Apr 01; 164(7):3460-4. Jarmin DI, Rits M, Bota D, Gerard NP, Graham GJ, Clark-Lewis I, Gerard C. PMID: 10725696.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    Daniela's Networks
    Concepts (364)
    Derived automatically from this person's publications.
    Co-Authors (50)
    People in Profiles who have published with this person.
    Similar People (60)
    People who share similar concepts with this person.
    Same Department
    Search Department