Hirohito Ichii

Title(s)Clinical Professor, Surgery
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-8429
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    1. Nrf2 Pathway and Oxidative Stress as a Common Target for Treatment of Diabetes and Its Comorbidities. Int J Mol Sci. 2024 Jan 09; 25(2). Yi M, Cruz Cisneros L, Cho EJ, Alexander M, Kimelman FA, Swentek L, Ferrey A, Tantisattamo E, Ichii H. PMID: 38255895; PMCID: PMC10815857.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Outcomes Among Undocumented Immigrant Kidney Transplant Recipients in California. JAMA Netw Open. 2023 02 01; 6(2):e2254660. Eguchi N, Tantisattamo E, Chung D, Reddy UG, Ferrey A, Dafoe D, Ichii H. PMID: 36780162; PMCID: PMC9926318.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Anti-Oxidative Therapy in Islet Cell Transplantation. Antioxidants (Basel). 2022 May 24; 11(6). Eguchi N, Damyar K, Alexander M, Dafoe D, Lakey JRT, Ichii H. PMID: 35739935; PMCID: PMC9219662.
      View in: PubMed   Mentions: 1  
    4. Anti-Oxidative Therapy in Diabetic Nephropathy. Front Biosci (Schol Ed). 2022 05 09; 14(2):14. Hernandez LF, Eguchi N, Whaley D, Alexander M, Tantisattamo E, Ichii H. PMID: 35730439.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    5. Dysregulation of β-Cell Proliferation in Diabetes: Possibilities of Combination Therapy in the Development of a Comprehensive Treatment. Biomedicines. 2022 Feb 17; 10(2). Eguchi N, Toribio AJ, Alexander M, Xu I, Whaley DL, Hernandez LF, Dafoe D, Ichii H. PMID: 35203680; PMCID: PMC8962301.
      View in: PubMed   Mentions: 2  
    6. Is It Time to Utilize Genetic Testing for Living Kidney Donor Evaluation? Nephron. 2022; 146(2):220-226. Tantisattamo E, Reddy UG, Ichii H, Ferrey AJ, Dafoe DC, Ioannou N, Xie J, Pitman TR, Hendricks E, Eguchi N, Kalantar-Zadeh K. PMID: 34883493; PMCID: PMC8985034.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Intraoperative Near-Infrared Spectroscopy Monitoring of Renal Allograft Reperfusion in Kidney Transplant Recipients: A Feasibility and Proof-of-Concept Study. J Clin Med. 2021 Sep 22; 10(19). Lau H, Lopez AJ, Eguchi N, Shimomura A, Ferrey A, Tantisattamo E, Reddy U, Dafoe D, Ichii H. PMID: 34640317; PMCID: PMC8509741.
      View in: PubMed   Mentions: 3  
    8. Kidney allograft infarction associated with transplant renal artery stenosis in a COVID-19 kidney transplant recipient. Clin Nephrol Case Stud. 2021; 9:93-104. Tantisattamo E, Dafoe DC, Ferrey AJ, Ichii H, Lee RA, Zuckerman JE, Sisk AEJ, Farzaneh T, Guccione J, Kabutey NK, Kalantar-Zadeh K, Reddy UG. PMID: 34476173; PMCID: PMC8387732.
      View in: PubMed   Mentions: 3  
    9. Antioxidant Therapy in Pancreatitis. Antioxidants (Basel). 2021 Apr 23; 10(5). Swentek L, Chung D, Ichii H. PMID: 33922756; PMCID: PMC8144986.
      View in: PubMed   Mentions: 3  
    10. Current Pharmacological Intervention and Medical Management for Diabetic Kidney Transplant Recipients. Pharmaceutics. 2021 Mar 19; 13(3). Klangjareonchai T, Eguchi N, Tantisattamo E, Ferrey AJ, Reddy U, Dafoe DC, Ichii H. PMID: 33808901; PMCID: PMC8003701.
      View in: PubMed   Mentions: 2  
    11. Interactive Virtual Reality Renal Models as an Educational and Preoperative Planning Tool for Laparoscopic Donor Nephrectomy. Urology. 2021 07; 153:192-198. Xie L, O'Leary M, Jefferson FA, Karani R, Limfueco L, Parkhomenko E, Sung JM, Patel RM, Ichii H, Dafoe D, Clayman RV, Landman J. PMID: 33556447.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. The Role of Oxidative Stress in Pancreatic β Cell Dysfunction in Diabetes. Int J Mol Sci. 2021 Feb 03; 22(4). Eguchi N, Vaziri ND, Dafoe DC, Ichii H. PMID: 33546200; PMCID: PMC7913369.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    13. Prevention of Autoimmune Diabetes in NOD Mice by Dimethyl Fumarate. Antioxidants (Basel). 2021 Jan 29; 10(2). Li S, Vaziri ND, Swentek L, Takasu C, Vo K, Stamos MJ, Ricordi C, Ichii H. PMID: 33572792; PMCID: PMC7912218.
      View in: PubMed   Mentions: 7  
    14. Association of age with risk of first and subsequent allograft failure and mortality among young kidney transplant recipients in the USA - a retrospective cohort study. Transpl Int. 2020 11; 33(11):1503-1515. Okuda Y, Streja E, Rhee CM, Tantisattamo E, Reddy U, Laster M, Tang Y, Rajpoot D, Molnar MZ, Ichii H, Obi Y, Kalantar-Zadeh K. PMID: 32779214.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. The Role of the Nrf2 Signaling in Obesity and Insulin Resistance. Int J Mol Sci. 2020 Sep 22; 21(18). Li S, Eguchi N, Lau H, Ichii H. PMID: 32971975; PMCID: PMC7555440.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    16. Hyponatremia: A possible immuno-neuroendocrine interface with COVID-19 in a kidney transplant recipient. Transpl Infect Dis. 2020 Dec; 22(6):e13355. Tantisattamo E, Reddy UG, Duong DK, Ferrey AJ, Ichii H, Dafoe DC, Kalantar-Zadeh K. PMID: 32510756.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    17. Haddon matrix for kidney transplantation during COVID-19 pandemic: A problem solving framework for present and future. Transpl Infect Dis. 2020 12; 22(6):e13373. Tantisattamo E, Ferrey AJ, Reddy UG, Ichii H, Dafoe DC, Kalantar-Zadeh K. PMID: 32562597; PMCID: PMC7323019.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    18. Approach and Management of Hypertension After Kidney Transplantation. Front Med (Lausanne). 2020; 7:229. Tantisattamo E, Molnar MZ, Ho BT, Reddy UG, Dafoe DC, Ichii H, Ferrey AJ, Hanna RM, Kalantar-Zadeh K, Amin A. PMID: 32613001; PMCID: PMC7310511.
      View in: PubMed   Mentions: 18  
    19. Evaluating the massive underreporting and undertesting of COVID-19 cases in multiple global epicenters. Pulmonology. 2021 Mar-Apr; 27(2):110-115. Lau H, Khosrawipour T, Kocbach P, Ichii H, Bania J, Khosrawipour V. PMID: 32540223; PMCID: PMC7275155.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    20. Failure in initial stage containment of global COVID-19 epicenters. J Med Virol. 2020 07; 92(7):863-867. Khosrawipour V, Lau H, Khosrawipour T, Kocbach P, Ichii H, Bania J, Mikolajczyk A. PMID: 32297980; PMCID: PMC7262316.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCellsPHPublic Health
    21. Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways. Antioxidants (Basel). 2020 Apr 24; 9(4). Li S, Takasu C, Lau H, Robles L, Vo K, Farzaneh T, Vaziri ND, Stamos MJ, Ichii H. PMID: 32344663; PMCID: PMC7222424.
      View in: PubMed   Mentions: 14  
    22. Potential Benefits of Nrf2/Keap1 Targeting in Pancreatic Islet Cell Transplantation. Antioxidants (Basel). 2020 Apr 16; 9(4). Jarrin Lopez A, Lau H, Li S, Ichii H. PMID: 32316115; PMCID: PMC7222398.
      View in: PubMed   Mentions: 9  
    23. The association between international and domestic air traffic and the coronavirus (COVID-19) outbreak. J Microbiol Immunol Infect. 2020 Jun; 53(3):467-472. Lau H, Khosrawipour V, Kocbach P, Mikolajczyk A, Ichii H, Zacharski M, Bania J, Khosrawipour T. PMID: 32299783; PMCID: PMC7271256.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansPHPublic Health
    24. Internationally lost COVID-19 cases. J Microbiol Immunol Infect. 2020 Jun; 53(3):454-458. Lau H, Khosrawipour V, Kocbach P, Mikolajczyk A, Ichii H, Schubert J, Bania J, Khosrawipour T. PMID: 32205091; PMCID: PMC7102572.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCellsPHPublic Health
    25. Novel options for failing allograft in kidney transplanted patients to avoid or defer dialysis therapy. Curr Opin Nephrol Hypertens. 2020 01; 29(1):80-91. Tantisattamo E, Hanna RM, Reddy UG, Ichii H, Dafoe DC, Danovitch GM, Kalantar-Zadeh K. PMID: 31743241; PMCID: PMC7454043.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    26. Utilization of Carbon Dioxide Angiography and Percutaneous Balloon Angioplasty for Treatment of Transplant Renal Artery Stenosis. Ann Vasc Surg. 2020 May; 65:10-16. Hasjim BJ, Fujitani RM, Chen SL, Donayre C, Kuo IJ, Raza A, Reddy U, Ichii H, Kabutey NK. PMID: 31712187.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Reducing Pancreatic Fibrosis Using Antioxidant Therapy Targeting Nrf2 Antioxidant Pathway: A Possible Treatment for Chronic Pancreatitis. Pancreas. 2019 Nov/Dec; 48(10):1259-1262. Kojayan GG, Alizadeh RF, Li S, Ichii H. PMID: 31688588.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    28. Monitoring kidney optical properties during cold storage preservation with spatial frequency domain imaging. J Biomed Opt. 2019 11; 24(11):1-7. Rowland R, Ponticorvo A, Jarrin Lopez A, Li S, Li X, Ichii H, Durkin A. PMID: 31777223; PMCID: PMC6882458.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    29. Current Management of Patients With Acquired Solitary Kidney. Kidney Int Rep. 2019 Sep; 4(9):1205-1218. Tantisattamo E, Dafoe DC, Reddy UG, Ichii H, Rhee CM, Streja E, Landman J, Kalantar-Zadeh K. PMID: 31517140; PMCID: PMC6732776.
      View in: PubMed   Mentions: 19  
    30. High and low estimated glomerular filtration rates are associated with adverse outcomes in patients undergoing surgery for gastrointestinal malignancies. Nephrol Dial Transplant. 2019 05 01; 34(5):810-818. Ui T, Obi Y, Shimomura A, Lefor AK, Fazl Alizadeh R, Said H, Nguyen NT, Stamos MJ, Kalantar-Zadeh K, Sata N, Ichii H. PMID: 29718365.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    31. Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerability in diabetes and islet transplantation. PLoS One. 2018; 13(5):e0196570. Miki A, Ricordi C, Sakuma Y, Yamamoto T, Misawa R, Mita A, Molano RD, Vaziri ND, Pileggi A, Ichii H. PMID: 29723228; PMCID: PMC5933778.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    32. Association of pre-operative estimated GFR on post-operative pulmonary complications in laparoscopic surgeries. Sci Rep. 2017 07 26; 7(1):6504. Shimomura A, Obi Y, Fazl Alizadeh R, Li S, Nguyen NT, Stamos MJ, Kalantar-Zadeh K, Ichii H. PMID: 28747700; PMCID: PMC5529443.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    33. Treatment with dimethyl fumarate ameliorates liver ischemia/reperfusion injury. World J Gastroenterol. 2017 Jul 07; 23(25):4508-4516. Takasu C, Vaziri ND, Li S, Robles L, Vo K, Takasu M, Pham C, Farzaneh SH, Shimada M, Stamos MJ, Ichii H. PMID: 28740339; PMCID: PMC5504366.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    34. Purified Human Pancreatic Islets, CIT Culture Media with Lisofylline or Exenatide. CellR4 Repair Replace Regen Reprogram. 2017; 5(3). NIH CIT Consortium Chemistry Manufacturing Controls Monitoring Committee, Ansite J, Balamurugan AN, Barbaro B, Battle J, Brandhorst D, Cano J, Chen X, Deng S, Feddersen D, Friberg A, Gilmore T, Goldstein JS, Holbrook E, Khan A, Kin T, Lei J, Linetsky E, Liu C, Luo X, McElvaney K, Min Z, Moreno J, O'Gorman D, Papas KK, Putz G, Ricordi C, Szot G, Templeton T, Wang L, Wilhelm JJ, Willits J, Wilson T, Zhang X, NIH CIT Consortium, Avila J, Begley B, Cano J, Carpentier S, Holbrook E, Hutchinson J, Larsen CP, Moreno J, Sears M, Turgeon NA, Webster D, Deng S, Lei J, Markmann JF, Bridges ND, Czarniecki CW, Goldstein JS, Putz G, Templeton T, Wilson T, Eggerman TL, Al-Saden P, Battle J, Chen X, Hecyk A, Kissler H, Luo X, Molitch M, Monson N, Stuart E, Wallia A, Wang L, Wang S, Zhang X, Bigam D, Campbell P, Dinyari P, Kin T, Kneteman N, Lyon J, Malcolm A, O'Gorman D, Onderka C, Owen R, Pawlick R, Richer B, Rosichuk S, Sarman D, Schroeder A, Senior PA, Shapiro AMJ, Toth L, Toth V, Zhai W, Johnson K, McElroy J, Posselt AM, Ramos M, Rojas T, Stock PG, Szot G, Barbaro B, Martellotto J, Oberholzer J, Qi M, Wang Y, Bayman L, Chaloner K, Clarke W, Dillon JS, Diltz C, Doelle GC, Ecklund D, Feddersen D, Foster E, Hunsicker LG, Jasperson C, Lafontant DE, McElvaney K, Neill-Hudson T, Nollen D, Qidwai J, Riss H, Schwieger T, Willits J, Yankey J, Alejandro R, Corrales AC, Faradji R, Froud T, Garcia AA, Herrada E, Ichii H, Inverardi L, Kenyon N, Khan A, Linetsky E, Montelongo J, Peixoto E, Peterson K, Ricordi C, Szust J, Wang X, Abdulla MH, Ansite J, Balamurugan AN, Bellin MD, Brandenburg M, Gilmore T, Harmon JV, Hering BJ, Kandaswamy R, Loganathan G, Mueller K, Papas KK, Pedersen J, Wilhelm JJ, Witson J, Dalton-Bakes C, Fu H, Kamoun M, Kearns J, Li Y, Liu C, Luning-Prak E, Luo Y, Markmann E, Min Z, Naji A, Palanjian M, Rickels M, Shlansky-Goldberg R, Vivek K, Ziaie AS, Fernandez L, Kaufman DB, Zitur L, Brandhorst D, Friberg A, Korsgren O. PMID: 30613755; PMCID: PMC6319648.
      View in: PubMed   Mentions:
    35. Risk of Postoperative Venous Thromboembolism Among Pregnant Women. Am J Cardiol. 2017 Aug 01; 120(3):479-483. Suematsu Y, Obi Y, Shimomura A, Alizadeh RF, Vaziri ND, Nguyen NT, Stamos MJ, Ichii H. PMID: 28595858.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Invasive squamous cell bladder cancer of the ureterovesical junction in a renal transplant patient: a case report. J Surg Case Rep. 2017 Feb; 2017(5):rjx066. Mowlds DS, Foster CE, Ichii H. PMID: 28479974; PMCID: PMC5411735.
      View in: PubMed   Mentions: 1  
    37. Post-transplantation nephroptosis causing recurrent episodes of acute renal failure and hypertension secondary to intermittent vascular torsion of intraperitoneal renal allograft. J Surg Case Rep. 2017 May; 2017(5):rjx033. Dosch AR, Pahl M, Reddy U, Foster CE, Ichii H. PMID: 28560019; PMCID: PMC5441242.
      View in: PubMed   Mentions: 1  
    38. A Nationwide Analysis of Kidney Autotransplantation. Am Surg. 2017 Feb 01; 83(2):162-169. Moghadamyeghaneh Z, Hanna MH, Fazlalizadeh R, Obi Y, Foster CE, Stamos MJ, Ichii H. PMID: 28228203.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    39. Synthetic Triterpenoid RTA dh404 (CDDO-dhTFEA) Ameliorates Acute Pancreatitis. Pancreas. 2016 May-Jun; 45(5):720-9. Robles L, Vaziri ND, Li S, Masuda Y, Takasu C, Takasu M, Vo K, Farzaneh SH, Stamos MJ, Ichii H. PMID: 26495793; PMCID: PMC5847282.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    40. Hand-Assisted Laparoscopic Donor Nephrectomy in Complete Situs Inversus. J Endourol Case Rep. 2016; 2(1):108-10. Gahagan JV, Whealon MD, Reddy U, Foster CE, Ichii H. PMID: 27579434; PMCID: PMC4996604.
      View in: PubMed   Mentions: 2  
    41. Treatment of Focal Segmental Glomerulosclerosis Recurrence in the Renal Allograft: A Report of Two Cases. Case Rep Nephrol Dial. 2016 Jan-Apr; 6(1):53-60. Tran MH, Chan C, Pasch W, Carpenter P, Ichii H, Foster C. PMID: 27099858; PMCID: PMC4836136.
      View in: PubMed   Mentions: 1  
    42. Kidney transplantation in obese patients. World J Transplant. 2016 Mar 24; 6(1):135-43. Tran MH, Foster CE, Kalantar-Zadeh K, Ichii H. PMID: 27011911; PMCID: PMC4801789.
      View in: PubMed   Mentions: 11  
    43. Total pancreatectomy and islet autotransplantation: A decade nationwide analysis. World J Transplant. 2016 Mar 24; 6(1):233-8. Fazlalizadeh R, Moghadamyeghaneh Z, Demirjian AN, Imagawa DK, Foster CE, Lakey JR, Stamos MJ, Ichii H. PMID: 27011922; PMCID: PMC4801800.
      View in: PubMed   Mentions: 7  
    44. The effect of Nrf2 pathway activation on human pancreatic islet cells. PLoS One. 2015; 10(6):e0131012. Masuda Y, Vaziri ND, Li S, Le A, Hajighasemi-Ossareh M, Robles L, Foster CE, Stamos MJ, Al-Abodullah I, Ricordi C, Ichii H. PMID: 26110640; PMCID: PMC4482439.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    45. Treatment With Dimethyl Fumarate Attenuates Calcineurin Inhibitor-induced Nephrotoxicity. Transplantation. 2015 Jun; 99(6):1144-50. Takasu C, Vaziri ND, Li S, Robles L, Vo K, Takasu M, Pham C, Liu S, Farzaneh SH, Foster CE, Stamos MJ, Ichii H. PMID: 25710612; PMCID: PMC4452388.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    46. Dimethyl fumarate ameliorates acute pancreatitis in rodent. Pancreas. 2015 Apr; 44(3):441-7. Robles L, Vaziri ND, Li S, Takasu C, Masuda Y, Vo K, Farzaneh SH, Stamos MJ, Ichii H. PMID: 25486529; PMCID: PMC4357568.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    47. Pharmacological activation of Nrf2 pathway improves pancreatic islet isolation and transplantation. Cell Transplant. 2015; 24(11):2273-83. Li S, Vaziri ND, Masuda Y, Hajighasemi-Ossareh M, Robles L, Le A, Vo K, Chan JY, Foster CE, Stamos MJ, Ichii H. PMID: 25581574.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    48. Improved human islet preparations using glucocorticoid and exendin-4. Pancreas. 2014 Nov; 43(8):1317-22. Miki A, Ricordi C, Yamamoto T, Sakuma Y, Misawa R, Mita A, Inverardi L, Alejandro R, Ichii H. PMID: 25036907; PMCID: PMC4206594.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    49. Dimethyl fumarate protects pancreatic islet cells and non-endocrine tissue in L-arginine-induced chronic pancreatitis. PLoS One. 2014; 9(9):e107111. Robles L, Vaziri ND, Li S, Masuda Y, Takasu C, Takasu M, Vo K, Farzaneh SH, Stamos MJ, Ichii H. PMID: 25198679; PMCID: PMC4157838.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    50. Cellular Composition and Fractional β-Cell Viability Assay. CellR4 Repair Replace Regen Reprogram. 2014; 2(4). Ichii H, Pileggi A, Molano RD, Linetsky E, Alejandro R, Inverardi L, Ricordi C. PMID: 30613696; PMCID: PMC6319378.
      View in: PubMed   Mentions:
    51. Salutary effect of pre-treatment with an Nrf2 inducer on ischemia reperfusion injury in the rat liver. Gastroenterol Hepatol (Que). 2014; 1(1):1-7. Masuda Y, Vaziri ND, Takasu C, Li S, Robles L, Pham C, Le A, Vo K, Farzaneh SH, Stamos MJ, Ichii H. PMID: 25558293; PMCID: PMC4280567.
      View in: PubMed   Mentions: 8  
    52. At pharmacologically relevant concentrations intravenous iron preparations cause pancreatic beta cell death. Am J Transl Res. 2013; 6(1):64-70. Masuda Y, Ichii H, Vaziri ND. PMID: 24349622; PMCID: PMC3853425.
      View in: PubMed   Mentions: 9  
    53. Timing of return to dialysis in patients with failing kidney transplants. Semin Dial. 2013 Nov-Dec; 26(6):667-74. Molnar MZ, Ichii H, Lineen J, Foster CE, Mathe Z, Schiff J, Kim SJ, Pahl MV, Amin AN, Kalantar-Zadeh K, Kovesdy CP. PMID: 24016076.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    54. Oral activated charcoal adsorbent (AST-120) ameliorates chronic kidney disease-induced intestinal epithelial barrier disruption. Am J Nephrol. 2013; 37(6):518-25. Vaziri ND, Yuan J, Khazaeli M, Masuda Y, Ichii H, Liu S. PMID: 23689670; PMCID: PMC3777856.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    55. Role of Oxidative Stress in the Pathogenesis of Pancreatitis: Effect of Antioxidant Therapy. Pancreat Disord Ther. 2013 Apr 01; 3(1):112. Robles L, Vaziri ND, Ichii H. PMID: 24808987; PMCID: PMC4009983.
      View in: PubMed   Mentions: 23  
    56. MicroRNA expression in alpha and beta cells of human pancreatic islets. PLoS One. 2013; 8(1):e55064. Klein D, Misawa R, Bravo-Egana V, Vargas N, Rosero S, Piroso J, Ichii H, Umland O, Zhijie J, Tsinoremas N, Ricordi C, Inverardi L, Domínguez-Bendala J, Pastori RL. PMID: 23383059; PMCID: PMC3558471.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    57. Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes. Am J Nephrol. 2012; 36(1):50-7. Ichii H, Masuda Y, Hassanzadeh T, Saffarian M, Gollapudi S, Vaziri ND. PMID: 22722756; PMCID: PMC3986045.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    58. The effects of digestion enzymes on islet viability and cellular composition. Cell Transplant. 2012; 21(4):649-55. Iglesias I, Valiente L, Shiang KD, Ichii H, Kandeel F, Al-Abdullah IH. PMID: 22236690.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    59. Induction therapy by anti-thymocyte globulin (rabbit) versus basiliximab in deceased donor renal transplants and the effect on delayed graft function and outcomes. Transplant Proc. 2012 Jan; 44(1):164-6. Foster CE, Weng RR, Piper M, Laugenou K, Ichii H, Lakey J, Malinoski D. PMID: 22310605.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    60. Function and viability of human islets encapsulated in alginate sheets: in vitro and in vivo culture. Transplant Proc. 2011 Nov; 43(9):3265-6. Lamb M, Storrs R, Li S, Liang O, Laugenour K, Dorian R, Chapman D, Ichii H, Imagawa D, Foster C, King S, Lakey JR. PMID: 22099772.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    61. Quantitative in situ analysis of FoxP3+ T regulatory cells on transplant tissue using laser scanning cytometry. Cell Transplant. 2012; 21(1):113-25. Takahashi H, Ruiz P, Ricordi C, Delacruz V, Miki A, Mita A, Misawa R, Barker S, Burke GW, Tzakis AG, Ichii H. PMID: 21929847; PMCID: PMC3777543.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    62. Evaluation of viable β-cell mass is useful for selecting collagenase for human islet isolation: comparison of collagenase NB1 and liberase HI. Cell Transplant. 2012; 21(1):39-47. Misawa R, Ricordi C, Miki A, Barker S, Molano RD, Khan A, Miyagawa S, Inverardi L, Alejandro R, Pileggi A, Ichii H. PMID: 21929867; PMCID: PMC3777446.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    63. Bcl6 is required for the development of mouse CD4+ and CD8α+ dendritic cells. J Immunol. 2011 Jan 01; 186(1):255-63. Ohtsuka H, Sakamoto A, Pan J, Inage S, Horigome S, Ichii H, Arima M, Hatano M, Okada S, Tokuhisa T. PMID: 21131418.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    64. Antiproinflammatory effects of iodixanol (OptiPrep)-based density gradient purification on human islet preparations. Cell Transplant. 2010; 19(12):1537-46. Mita A, Ricordi C, Messinger S, Miki A, Misawa R, Barker S, Molano RD, Haertter R, Khan A, Miyagawa S, Pileggi A, Inverardi L, Alejandro R, Hering BJ, Ichii H. PMID: 20719078; PMCID: PMC3777530.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    65. Prolactin supplementation to culture medium improves beta-cell survival. Transplantation. 2010 Jun 15; 89(11):1328-35. Yamamoto T, Mita A, Ricordi C, Messinger S, Miki A, Sakuma Y, Timoneri F, Barker S, Fornoni A, Molano RD, Inverardi L, Pileggi A, Ichii H. PMID: 20357700; PMCID: PMC3780980.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    66. Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells. Diabetes. 2010 Apr; 59(4):947-57. Vendrame F, Pileggi A, Laughlin E, Allende G, Martin-Pagola A, Molano RD, Diamantopoulos S, Standifer N, Geubtner K, Falk BA, Ichii H, Takahashi H, Snowhite I, Chen Z, Mendez A, Chen L, Sageshima J, Ruiz P, Ciancio G, Ricordi C, Reijonen H, Nepom GT, Burke GW, Pugliese A. PMID: 20086230; PMCID: PMC2844842.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimalsCells
    67. Effects of pancreas cold ischemia on islet function and quality. Transplant Proc. 2009 Jun; 41(5):1808-9. Pileggi A, Ribeiro MM, Hogan AR, Molano RD, Embury JE, Ichii H, Cobianchi L, Fornoni A, Ricordi C, Pastori RL. PMID: 19545733.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    68. Impact of pancreatic cold preservation on rat islet recovery and function. Transplantation. 2009 May 27; 87(10):1442-50. Pileggi A, Ribeiro MM, Hogan AR, Molano RD, Cobianchi L, Ichii H, Embury J, Inverardi L, Fornoni A, Ricordi C, Pastori RL. PMID: 19461479.
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    69. C-type natriuretic peptide receptor expression in pancreatic alpha cells. Histochem Cell Biol. 2009 Jul; 132(1):95-103. Burgess MD, Moore KD, Carter GM, Alli AA, Granda CS, Ichii H, Ricordi C, Gower WR. PMID: 19352691.
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    70. Quality control for clinical islet transplantation: organ procurement and preservation, the islet processing facility, isolation, and potency tests. J Hepatobiliary Pancreat Surg. 2009; 16(2):131-6. Yamamoto T, Horiguchi A, Ito M, Nagata H, Ichii H, Ricordi C, Miyakawa S. PMID: 19242650.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    71. In situ quantitative immunoprofiling of regulatory T cells using laser scanning cytometry. Transplant Proc. 2009 Jan-Feb; 41(1):238-9. Takahashi H, Ruiz P, Ricordi C, Miki A, Mita A, Barker S, Tzakis A, Ichii H. PMID: 19249524; PMCID: PMC3777540.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    72. Purification method using iodixanol (OptiPrep)-based density gradient significantly reduces cytokine chemokine production from human islet preparations, leading to prolonged beta-cell survival during pretransplantation culture. Transplant Proc. 2009 Jan-Feb; 41(1):314-5. Mita A, Ricordi C, Miki A, Barker S, Khan A, Alvarez A, Hashikura Y, Miyagawa S, Ichii H. PMID: 19249543; PMCID: PMC3780973.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    73. Effect of pituitary adenylate cyclase-activating polypeptide in islet transplantation. Transplant Proc. 2009 Jan-Feb; 41(1):343-5. Sakuma Y, Ricordi C, Miki A, Yamamoto T, Mita A, Barker S, Damaris RM, Pileggi A, Yasuda Y, Yada T, Ichii H. PMID: 19249552; PMCID: PMC3777528.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    74. Toward improving human islet isolation from younger donors: rescue purification is efficient for trapped islets. Cell Transplant. 2009; 18(1):13-22. Miki A, Ricordi C, Messinger S, Yamamoto T, Mita A, Barker S, Haetter R, Khan A, Alejandro R, Ichii H. PMID: 19476205; PMCID: PMC3777447.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    75. Current status of islet cell transplantation. J Hepatobiliary Pancreat Surg. 2009; 16(2):101-12. Ichii H, Ricordi C. PMID: 19110649; PMCID: PMC3777531.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    76. c-Jun N-terminal kinase 1 is deleterious to the function and survival of murine pancreatic islets. Diabetologia. 2008 Dec; 51(12):2271-80. Varona-Santos JL, Pileggi A, Molano RD, Sanabria NY, Ijaz A, Atsushi M, Ichii H, Pastori RL, Inverardi L, Ricordi C, Fornoni A. PMID: 18853132.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    77. Characterization of pancreatic ductal cells in human islet preparations. Lab Invest. 2008 Nov; 88(11):1167-77. Ichii H, Miki A, Yamamoto T, Molano RD, Barker S, Mita A, Rodriguez-Diaz R, Klein D, Pastori R, Alejandro R, Inverardi L, Pileggi A, Ricordi C. PMID: 18779781; PMCID: PMC3793849.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    78. CD40 activation in human pancreatic islets and ductal cells. Diabetologia. 2008 Oct; 51(10):1853-61. Klein D, Timoneri F, Ichii H, Ricordi C, Pastori RL. PMID: 18661119.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    79. Anti-proinflammatory effects of sirolimus on human islet preparations. Transplantation. 2008 Jul 15; 86(1):46-53. Mita A, Ricordi C, Miki A, Barker S, Haertter R, Hashikura Y, Miyagawa S, Burke GW, Inverardi L, Ichii H. PMID: 18622277; PMCID: PMC2650480.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    80. Factors that affect human islet isolation. Transplant Proc. 2008 Mar; 40(2):343-5. Sakuma Y, Ricordi C, Miki A, Yamamoto T, Pileggi A, Khan A, Alejandro R, Inverardi L, Ichii H. PMID: 18374062; PMCID: PMC2614209.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    81. Effect of human islet rescue gradient purification on islet yield and fractional Beta cell viability. Transplant Proc. 2008 Mar; 40(2):360-1. Miki A, Ricordi C, Yamamoto T, Mita A, Barker S, Khan A, Alejandro R, Ichii H. PMID: 18374067; PMCID: PMC2614214.
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    82. beta-Cell specific cytoprotection by prolactin on human islets. Transplant Proc. 2008 Mar; 40(2):382-3. Yamamoto T, Ricordi C, Mita A, Miki A, Sakuma Y, Molano RD, Fornoni A, Pileggi A, Inverardi L, Ichii H. PMID: 18374075; PMCID: PMC2614218.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    83. Rapamycin impairs beta-cell proliferation in vivo. Transplant Proc. 2008 Mar; 40(2):436-7. Zahr E, Molano RD, Pileggi A, Ichii H, San Jose S, Bocca N, An W, Gonzalez-Quintana J, Fraker C, Ricordi C, Inverardi L. PMID: 18374093.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    84. Protection of human pancreatic islets using a lentiviral vector expressing two genes: cFLIP and GFP. Cell Transplant. 2008; 17(7):793-802. Fenjves ES, Ochoa MS, Cechin S, Gay-Rabinstein C, Pérez-Alvarez I, Ichii H, Mendez A, Ricordi C, Curran MA. PMID: 19044206.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    85. Rapamycin impairs in vivo proliferation of islet beta-cells. Transplantation. 2007 Dec 27; 84(12):1576-83. Zahr E, Molano RD, Pileggi A, Ichii H, Jose SS, Bocca N, An W, Gonzalez-Quintana J, Fraker C, Ricordi C, Inverardi L. PMID: 18165767.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    86. Inhibition of c-jun N terminal kinase (JNK) improves functional beta cell mass in human islets and leads to AKT and glycogen synthase kinase-3 (GSK-3) phosphorylation. Diabetologia. 2008 Feb; 51(2):298-308. Fornoni A, Pileggi A, Molano RD, Sanabria NY, Tejada T, Gonzalez-Quintana J, Ichii H, Inverardi L, Ricordi C, Pastori RL. PMID: 18066521.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    87. Deterioration and variability of highly purified collagenase blends used in clinical islet isolation. Transplantation. 2007 Oct 27; 84(8):997-1002. Yamamoto T, Ricordi C, Messinger S, Sakuma Y, Miki A, Rodriguez R, Haertter R, Khan A, Alejandro R, Ichii H. PMID: 17989605.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    88. Shipment of human islets for transplantation. Am J Transplant. 2007 Apr; 7(4):1010-20. Ichii H, Sakuma Y, Pileggi A, Fraker C, Alvarez A, Montelongo J, Szust J, Khan A, Inverardi L, Naziruddin B, Levy MF, Klintmalm GB, Goss JA, Alejandro R, Ricordi C. PMID: 17391141.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    89. Bcl6 is essential for the generation of long-term memory CD4+ T cells. Int Immunol. 2007 Apr; 19(4):427-33. Ichii H, Sakamoto A, Arima M, Hatano M, Kuroda Y, Tokuhisa T. PMID: 17307796.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    90. The l-isoform but not d-isoforms of a JNK inhibitory peptide protects pancreatic beta-cells. Biochem Biophys Res Commun. 2007 Mar 02; 354(1):227-33. Fornoni A, Cobianchi L, Sanabria NY, Pileggi A, Molano RD, Ichii H, Rosero S, Inverardi L, Ricordi C, Pastori RL. PMID: 17222390.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    91. Toward maximizing the success rates of human islet isolation: influence of donor and isolation factors. Cell Transplant. 2007; 16(6):595-607. Ponte GM, Pileggi A, Messinger S, Alejandro A, Ichii H, Baidal DA, Khan A, Ricordi C, Goss JA, Alejandro R. PMID: 17912951.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    92. CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets. Diabetes. 2006 Sep; 55(9):2437-45. Barbé-Tuana FM, Klein D, Ichii H, Berman DM, Coffey L, Kenyon NS, Ricordi C, Pastori RL. PMID: 16936191.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    93. Improved human islet isolation using nicotinamide. Am J Transplant. 2006 Sep; 6(9):2060-8. Ichii H, Wang X, Messinger S, Alvarez A, Fraker C, Khan A, Kuroda Y, Inverardi L, Goss JA, Alejandro R, Ricordi C. PMID: 16827790.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    94. The use of the BD oxygen biosensor system to assess isolated human islets of langerhans: oxygen consumption as a potential measure of islet potency. Cell Transplant. 2006; 15(8-9):745-58. Fraker C, Timmins MR, Guarino RD, Haaland PD, Ichii H, Molano D, Pileggi A, Poggioli R, Presnell SC, Inverardi L, Zehtab M, Ricordi C. PMID: 17269445.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    95. Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience. Am J Transplant. 2005 Aug; 5(8):2037-46. Froud T, Ricordi C, Baidal DA, Hafiz MM, Ponte G, Cure P, Pileggi A, Poggioli R, Ichii H, Khan A, Ferreira JV, Pugliese A, Esquenazi VV, Kenyon NS, Alejandro R. PMID: 15996257.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansCTClinical Trials
    96. A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations. Am J Transplant. 2005 Jul; 5(7):1635-45. Ichii H, Inverardi L, Pileggi A, Molano RD, Cabrera O, Caicedo A, Messinger S, Kuroda Y, Berggren PO, Ricordi C. PMID: 15943621.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    97. A functional CD40 receptor is expressed in pancreatic beta cells. Diabetologia. 2005 Feb; 48(2):268-76. Klein D, Barbé-Tuana F, Pugliese A, Ichii H, Garza D, Gonzalez M, Molano RD, Ricordi C, Pastori RL. PMID: 15690148.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    98. Prolonged Allogeneic Islet Graft Survival by Protoporphyrins. Cell Transplant. 2005 Feb/Mar; 14(2-3):85-96. Pileggi A, Molano RD, Berney T, Ichii H, Jose SS, Zahr E, Poggioli R, Linetsky E, Ricordi C, Inverardi L. PMID: 28871856.
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    99. Prolonged allogeneic islet graft survival by protoporphyrins. Cell Transplant. 2005; 14(2-3):85-96. Pileggi A, Molano RD, Berney T, Ichii H, San Jose S, Zahr E, Poggioli R, Linetsky E, Ricordi C, Inverardi L. PMID: 15881418.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    100. Rescue purification maximizes the use of human islet preparations for transplantation. Am J Transplant. 2005 Jan; 5(1):21-30. Ichii H, Pileggi A, Molano RD, Baidal DA, Khan A, Kuroda Y, Inverardi L, Goss JA, Alejandro R, Ricordi C. PMID: 15636608.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    101. Protection of islets in culture by delivery of oxygen binding neuroglobin via protein transduction. Transplant Proc. 2005 Jan-Feb; 37(1):237-40. Mendoza V, Klein D, Ichii H, Ribeiro MM, Ricordi C, Hankeln T, Burmester T, Pastori RL. PMID: 15808606.
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    102. Bcl6 acts as an amplifier for the generation and proliferative capacity of central memory CD8+ T cells. J Immunol. 2004 Jul 15; 173(2):883-91. Ichii H, Sakamoto A, Kuroda Y, Tokuhisa T. PMID: 15240675.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    103. A putative silencer element in the IL-5 gene recognized by Bcl6. J Immunol. 2002 Jul 15; 169(2):829-36. Arima M, Toyama H, Ichii H, Kojima S, Okada S, Hatano M, Cheng G, Kubo M, Fukuda T, Tokuhisa T. PMID: 12097386.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    104. Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells. Nat Immunol. 2002 Jun; 3(6):558-63. Ichii H, Sakamoto A, Hatano M, Okada S, Toyama H, Taki S, Arima M, Kuroda Y, Tokuhisa T. PMID: 12021781.
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    105. Three-dimensional reconstruction of biliary tract using spiral computed tomography for laparoscopic cholecystectomy. World J Surg. 2002 May; 26(5):608-11. Ichii H, Takada M, Kashiwagi R, Sakane M, Tabata F, Ku Y, Fujimori T, Kuroda Y. PMID: 12098055.
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    106. Tc-99m sestamibi uptake in tuberculosis of the breast. Clin Nucl Med. 1998 Feb; 23(2):106-8. Ohta H, Ichii H, Arimoto A, Ukikusa M, Awane H. PMID: 9481502.
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    107. Monoterpene synthases from gymnosperms and angiosperms: stereospecificity and inactivation by cysteinyl- and arginyl-directed modifying reagents. Arch Biochem Biophys. 1995 Jul 10; 320(2):257-65. Savage TJ, Ichii H, Hume SD, Little DB, Croteau R. PMID: 7625832.
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    108. [Rapid progression of pulmonary metastatic choriocarcinoma (author's transl)]. Rinsho Hoshasen. 1979 Mar; 24(3):415-9. Sone S, Higashihara T, Yokota K, Morimoto S, Ikezoe J, Ichii H. PMID: 575725.
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    109. [Scintigraphic study of radiation effect on parametrium infiltration of cervical cancer (author's transl)]. Nihon Gan Chiryo Gakkai Shi. 1975 Dec 20; 10(4):475-87. Miura S, Hirota Y, Hamanaka N, Kawamura Y, Ichii H. PMID: 1240910.
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    110. [Serum LH(HCG) and FSH--interpretation of the test results]. Nihon Rinsho. 1973; 31:1606-14. Tanizawa O, Aono T, Minamikawa J, Ichii H, Kawamura K. PMID: 4795301.
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    111. Clinical, histochemical, and biochemical studies of an ovarian dysgerminoma with trophoblasts and Leydig cells. Am J Obstet Gynecol. 1972 Nov 15; 114(6):748-54. Ueda G, Hamanaka N, Hayakawa K, Tanizawa O, Ichii H, Nakagawa H, Mineda H, Furuyama J, Matsumoto K, Mori M. PMID: 4676571.
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    112. [Radioimmunoassay of human placental lactogen and its clinical application]. Saishin Igaku. 1971 Jun; 26(6):1131-6. Tanizawa O, Ichii H, Miyata J, Matsuo K. PMID: 5098178.
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