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Edward M Uchio

Title(s)Clinical Professor, Urology
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-6896
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Aquablation for benign prostatic hyperplasia in large prostates (80-150 cc): 2-year results. Can J Urol. 2020 Apr; 27(2):10147-10153. Desai M, Bidair M, Bhojani N, Trainer A, Arther A, Kramolowsky E, Doumanian L, Elterman D, Kaufman RP, Lingeman J, Krambeck A, Eure G, Badlani G, Plante M, Uchio E, Gin G, Goldenberg L, Paterson R, So A, Humphreys MR, Roehrborn CG, Kaplan S, Motola J, Zorn KC. PMID: 32333733.
      View in: PubMed   Mentions:    Fields:    
    2. Veterans Affairs Cooperative Studies Program Study #553: Chemotherapy After Prostatectomy for High-risk Prostate Carcinoma: A Phase III Randomized Study. Eur Urol. 2020 May; 77(5):563-572. Lin DW, Shih MC, Aronson W, Basler J, Beer TM, Brophy M, Cooperberg M, Garzotto M, Kelly WK, Lee K, McGuire V, Wang Y, Lu Y, Markle V, Nseyo U, Ringer R, Savage SJ, Sinnott P, Uchio E, Yang CC, Montgomery RB. PMID: 31924316.
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    3. Predictors of Recurrence, and Progression-Free and Overall Survival following Open versus Robotic Radical Cystectomy: Analysis from the RAZOR Trial with a 3-Year Followup. J Urol. 2020 03; 203(3):522-529. Venkatramani V, Reis IM, Castle EP, Gonzalgo ML, Woods ME, Svatek RS, Weizer AZ, Konety BR, Tollefson M, Krupski TL, Smith ND, Shabsigh A, Barocas DA, Quek ML, Dash A, Kibel AS, Pruthi RS, Montgomery JS, Weight CJ, Sharp DS, Chang SS, Cookson MS, Gupta GN, Gorbonos A, Uchio EM, Skinner E, Soodana-Prakash N, Becerra MF, Swain S, Kendrick K, Smith JA, Thompson IM, Parekh DJ. PMID: 31549935.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    4. PI-RADS Version 2 Is an Excellent Screening Tool for Clinically Significant Prostate Cancer as Designated by the Validated International Society of Urological Pathology Criteria: A Retrospective Analysis. Curr Probl Diagn Radiol. 2019 Jun 29. Daun M, Fardin S, Ushinsky A, Batra S, Nguyentat M, Lee T, Uchio E, Lall C, Houshyar R. PMID: 31350101.
      View in: PubMed   Mentions: 1     Fields:    
    5. Aquablation for Benign Prostatic Hyperplasia in Large Prostates (80-150 cc): 1-Year Results. Urology. 2019 Jul; 129:1-7. Bhojani N, Bidair M, Zorn KC, Trainer A, Arther A, Kramolowsky E, Doumanian L, Elterman D, Kaufman RP, Lingeman J, Krambeck A, Eure G, Badlani G, Plante M, Uchio E, Gin G, Goldenberg L, Paterson R, So A, Humphreys M, Kaplan S, Motola J, Desai M, Roehrborn C. PMID: 31059728.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    6. Aquablation for benign prostatic hyperplasia in large prostates (80-150 mL): 6-month results from the WATER II trial. BJU Int. 2019 08; 124(2):321-328. Desai M, Bidair M, Zorn KC, Trainer A, Arther A, Kramolowsky E, Doumanian L, Elterman D, Kaufman RP, Lingeman J, Krambeck A, Eure G, Badlani G, Plante M, Uchio E, Gin G, Goldenberg L, Paterson R, So A, Humphreys M, Roehrborn C, Kaplan S, Motola J, Bhojani N. PMID: 30734990.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    7. Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation. Cell Commun Signal. 2019 03 18; 17(1):25. Li X, Pham V, Tippin M, Fu D, Rendon R, Song L, Uchio E, Hoang BH, Zi X. PMID: 30885218.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density. J Investig Med. 2018 12; 66(8):1142-1146. Calvocoressi L, Uchio E, Ko J, Radhakrishnan K, Aslan M, Concato J. PMID: 30297390.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. A Randomized, Double-blind, Phase II Trial of PSA-TRICOM (PROSTVAC) in Patients with Localized Prostate Cancer: The Immunotherapy to Prevent Progression on Active Surveillance Study. Eur Urol Focus. 2018 09; 4(5):636-638. Parsons JK, Pinto PA, Pavlovich CP, Uchio E, Kim HL, Nguyen MN, Gulley JL, Jamieson C, Hsu P, Wojtowicz M, Parnes H, Schlom J, Dahut WL, Madan RA, Donahue RN, Chow HS. PMID: 30197041.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    10. Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial. Lancet. 2018 06 23; 391(10139):2525-2536. Parekh DJ, Reis IM, Castle EP, Gonzalgo ML, Woods ME, Svatek RS, Weizer AZ, Konety BR, Tollefson M, Krupski TL, Smith ND, Shabsigh A, Barocas DA, Quek ML, Dash A, Kibel AS, Shemanski L, Pruthi RS, Montgomery JS, Weight CJ, Sharp DS, Chang SS, Cookson MS, Gupta GN, Gorbonos A, Uchio EM, Skinner E, Venkatramani V, Soodana-Prakash N, Kendrick K, Smith JA, Thompson IM. PMID: 29976469.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    11. Utility of quantitative apparent diffusion coefficient measurements and normalized apparent diffusion coefficient ratios in the diagnosis of clinically significant peripheral zone prostate cancer. Br J Radiol. 2018 Jul; 91(1088):20180091. Nguyen TB, Ushinsky A, Yang A, Nguyentat M, Fardin S, Uchio E, Lall C, Lee T, Houshyar R. PMID: 29869921.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. WATER II (80-150 mL) procedural outcomes. BJU Int. 2019 01; 123(1):106-112. Desai M, Bidair M, Bhojani N, Trainer A, Arther A, Kramolowsky E, Doumanian L, Elterman D, Kaufman RP, Lingeman J, Krambeck A, Eure G, Badlani G, Plante M, Uchio E, Gin G, Goldenberg L, Paterson R, So A, Humphreys M, Roehrborn C, Kaplan S, Motola J, Zorn KC. PMID: 29694702.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    13. Multi-institutional Evaluation of Upper Urinary Tract Biopsy Using Backloaded Cup Biopsy Forceps, a Nitinol Basket, and Standard Cup Biopsy Forceps. Urology. 2018 Jul; 117:89-94. Lama DJ, Safiullah S, Patel RM, Lee TK, Balani JP, Zhang L, Okhunov Z, Margulis V, Savage SJ, Uchio E, Landman J. PMID: 29630955.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Prostatectomy-based validation of combined urine and plasma test for predicting high grade prostate cancer. Prostate. 2018 03; 78(4):294-299. Albitar M, Ma W, Lund L, Shahbaba B, Uchio E, Feddersen S, Moylan D, Wojno K, Shore N. PMID: 29315679.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    15. A Multi-Institutional Prospective Trial Confirms Noninvasive Blood Test Maintains Predictive Value in African American Men. J Urol. 2018 06; 199(6):1459-1463. Punnen S, Freedland SJ, Polascik TJ, Loeb S, Risk MC, Savage S, Mathur SC, Uchio E, Dong Y, Silberstein JL. PMID: 29223389.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    16. Development and Validation of a Novel Integrated Clinical-Genomic Risk Group Classification for Localized Prostate Cancer. J Clin Oncol. 2018 02 20; 36(6):581-590. Spratt DE, Zhang J, Santiago-Jiménez M, Dess RT, Davis JW, Den RB, Dicker AP, Kane CJ, Pollack A, Stoyanova R, Abdollah F, Ross AE, Cole A, Uchio E, Randall JM, Nguyen H, Zhao SG, Mehra R, Glass AG, Lam LLC, Chelliserry J, du Plessis M, Choeurng V, Aranes M, Kolisnik T, Margrave J, Alter J, Jordan J, Buerki C, Yousefi K, Haddad Z, Davicioni E, Trabulsi EJ, Loeb S, Tewari A, Carroll PR, Weinmann S, Schaeffer EM, Klein EA, Karnes RJ, Feng FY, Nguyen PL. PMID: 29185869.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. Trajectories of prostate-specific antigen after treatment for prostate cancer. J Investig Med. 2018 04; 66(4):768-772. Wu Z, Aslan M, Lin H, Ko J, Radhakrishnan K, Wells CK, Uchio E, Concato J. PMID: 29170243.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Validation of Prostate Imaging-Reporting and Data System Version 2: A Retrospective Analysis. Curr Probl Diagn Radiol. 2018 Nov; 47(6):404-409. Nguyentat M, Ushinsky A, Miranda-Aguirre A, Uchio E, Lall C, Shirkhoda L, Lee T, Green C, Houshyar R. PMID: 29126575.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Rhodiola rosea L.: an herb with anti-stress, anti-aging, and immunostimulating properties for cancer chemoprevention. Curr Pharmacol Rep. 2017 Dec; 3(6):384-395. Li Y, Pham V, Bui M, Song L, Wu C, Walia A, Uchio E, Smith-Liu F, Zi X. PMID: 30393593.
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    20. A Multi-Center Prospective Study to Validate an Algorithm Using Urine and Plasma Biomarkers for Predicting Gleason =3+4 Prostate Cancer on Biopsy. J Cancer. 2017; 8(13):2554-2560. Albitar M, Ma W, Lund L, Shahbaba B, Uchio E, Feddersen S, Moylan D, Wojno K, Shore N. PMID: 28900493.
      View in: PubMed   Mentions:
    21. Utilization of perioperative systemic chemotherapy in upper tract urothelial carcinoma. Urol Oncol. 2017 05; 35(5):192-200. Gin GE, Ruel NH, Kardos SV, Sfakianos JP, Uchio E, Lau CS, Yuh BE. PMID: 28041996.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. Predictors of Complications After Percutaneous Image-Guided Renal Cryoablation for T1a Renal Cortical Neoplasms. J Endourol. 2017 01; 31(1):7-13. Okhunov Z, Moreira DM, Del Junco M, Abedi G, Lobko II, Kaler KS, Nguyen ND, Youssef R, Uchio E, Kavoussi LR, Landman J. PMID: 27784185.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Deciphering the Effect of Metformin on Prostate Cancer Risk by Ethnicity. Cancer Prev Res (Phila). 2016 10; 9(10):777-778. Uchio E, Meyskens FL, Wang PH. PMID: 27432345.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. High Sensitivity of an Ha-RAS Transgenic Model of Superficial Bladder Cancer to Metformin Is Associated with ~240-Fold Higher Drug Concentration in Urine than Serum. Mol Cancer Ther. 2016 Mar; 15(3):430-8. Liu Z, Yokoyama NN, Blair CA, Li X, Avizonis D, Wu XR, Uchio E, Youssef R, McClelland M, Pollak M, Zi X. PMID: 26921394.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    25. Velocity and doubling time of prostate-specific antigen: mathematics can matter. J Investig Med. 2016 Feb; 64(2):400-4. Uchio E, Aslan M, Ko J, Wells CK, Radhakrishnan K, Concato J. PMID: 26767890.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Prostate cancer on computed tomography: A direct comparison with multi-parametric magnetic resonance imaging and tissue pathology. Eur J Radiol. 2016 Jan; 85(1):261-267. Jia JB, Houshyar R, Verma S, Uchio E, Lall C. PMID: 26526901.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. When Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow? Curr Pharmacol Rep. 2015 Dec 01; 1(6):420-433. Yokoyama NN, Denmon A, Uchio EM, Jordan M, Mercola D, Zi X. PMID: 26756023.
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    28. Expert consensus document: Consensus statement on best practice management regarding the use of intravesical immunotherapy with BCG for bladder cancer. Nat Rev Urol. 2015 04; 12(4):225-35. Kamat AM, Flaig TW, Grossman HB, Konety B, Lamm D, O'Donnell MA, Uchio E, Efstathiou JA, Taylor JA. PMID: 25800393.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    29. 'Race' and prostate cancer mortality in equal-access healthcare systems. Am J Med. 2013 Dec; 126(12):1084-8. Graham-Steed T, Uchio E, Wells CK, Aslan M, Ko J, Concato J. PMID: 24262722.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    30. Effects of androgen deprivation on cerebral morphometry in prostate cancer patients--an exploratory study. PLoS One. 2013; 8(8):e72032. Chao HH, Hu S, Ide JS, Uchio E, Zhang S, Rose M, Concato J, Li CS. PMID: 23977199.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    31. Robotic-assisted prostatectomy and open radical retropubic prostatectomy for locally-advanced prostate cancer: multi-institution comparison of oncologic outcomes. Prostate Int. 2013; 1(1):31-6. Vora AA, Marchalik D, Kowalczyk KJ, Nissim H, Bandi G, McGeagh KG, Lynch JH, Ghasemian SR, Verghese M, Venkatesan K, Borges P, Uchio EM, Hwang JJ. PMID: 24223399.
      View in: PubMed   Mentions:
    32. Effects of androgen deprivation on brain function in prostate cancer patients - a prospective observational cohort analysis. BMC Cancer. 2012 Aug 27; 12:371. Chao HH, Uchio E, Zhang S, Hu S, Bednarski SR, Luo X, Rose M, Concato J, Li CS. PMID: 22925152.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    33. Intermedin is overexpressed in hepatocellular carcinoma and regulates cell proliferation and survival. Cancer Sci. 2012 Aug; 103(8):1474-80. Guo X, Schmitz JC, Kenney BC, Uchio EM, Kulkarni S, Cha CH. PMID: 22625651.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    34. Laparoscopic repair of inguinal cystocele using cystoscopic light test. Urology. 2012 Mar; 79(3):725-7. Uchio EM, Calderon JS, Hwang JJ. PMID: 22386428.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. A novel device for minimally invasive harvest of the sural nerve. Conn Med. 2012 Jan; 76(1):27-31. Uchio E, Hoang D, Alam S, McRae M, Kishinevsky A, Narayan D. PMID: 22372176.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Poliomyelitis in MuLV-infected ICR-SCID mice after injection of basement membrane matrix contaminated with lactate dehydrogenase-elevating virus. Comp Med. 2011 Oct; 61(5):404-11. Carlson Scholz JA, Garg R, Compton SR, Allore HG, Zeiss CJ, Uchio EM. PMID: 22330347.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    37. Impact of biochemical recurrence in prostate cancer among US veterans. Arch Intern Med. 2010 Aug 09; 170(15):1390-5. Uchio EM, Aslan M, Wells CK, Calderone J, Concato J. PMID: 20696967.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    38. Changes in Gleason scores for prostate cancer: what should we expect from a measurement? J Investig Med. 2010 Apr; 58(4):625-8. Ramos J, Uchio E, Aslan M, Concato J. PMID: 20224436.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Prostate cancer, comorbidity, and participation in randomized controlled trials of therapy. J Investig Med. 2010 Mar; 58(3):566-8. Chao HH, Mayer T, Concato J, Rose MG, Uchio E, Kelly WK. PMID: 20072029.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    40. Relevance of molecular markers in prostate cancer. Ann Intern Med. 2009 Dec 15; 151(12):894; author reply 894-5. Concato J, Uchio E, Wells CK. PMID: 20008768.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    41. Molecular markers and death from prostate cancer. Ann Intern Med. 2009 May 05; 150(9):595-603. Concato J, Jain D, Uchio E, Risch H, Li WW, Wells CK. PMID: 19414838.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    42. Tissue microarray analysis of 560 patients with colorectal adenocarcinoma: high expression of HuR predicts poor survival. Ann Surg Oncol. 2009 Jan; 16(1):200-7. Yoo PS, Sullivan CA, Kiang S, Gao W, Uchio EM, Chung GG, Cha CH. PMID: 19009247.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    43. Downregulation of survivin is associated with reductions in TNF receptors' mRNA and protein and alterations in nuclear factor kappa B signaling in urothelial cancer cells. Cancer Invest. 2007 Dec; 25(8):678-84. Takizawa BT, Uchio EM, Cohen JJ, Wheeler MA, Weiss RM. PMID: 18058462.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    44. Molecular markers and mortality in prostate cancer. BJU Int. 2007 Dec; 100(6):1259-63. Concato J, Jain D, Li WW, Risch HA, Uchio EM, Wells CK. PMID: 17850375.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    45. Short interfering RNA-mediated gene silencing of vascular endothelial growth factor: effects on cellular proliferation in colon cancer cells. Arch Surg. 2006 Apr; 141(4):367-74; discussion 374. Mulkeen AL, Silva T, Yoo PS, Schmitz JC, Uchio E, Chu E, Cha C. PMID: 16618894.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    46. Mistaken identifiers: gene name errors can be introduced inadvertently when using Excel in bioinformatics. BMC Bioinformatics. 2004 Jun 23; 5:80. Zeeberg BR, Riss J, Kane DW, Bussey KJ, Uchio E, Linehan WM, Barrett JC, Weinstein JN. PMID: 15214961.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
    47. Laparoscopic management of extra-adrenal pheochromocytoma. J Urol. 2004 Jan; 171(1):72-6. Hwang J, Shoaf G, Uchio EM, Watson J, Pacak K, Linehan WM, Walther MM. PMID: 14665847.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    48. Prostate cancer in Klinefelter syndrome during hormonal replacement therapy. Urology. 2003 Nov; 62(5):941. Hwang JJ, Dharmawardana PG, Uchio EM, Wynberg J, Phillips JL. PMID: 14624928.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    49. Hereditary kidney cancer. Urol Clin North Am. 2003 Nov; 30(4):831-42. Hwang JJ, Uchio EM, Linehan WM, Walther MM. PMID: 14680318.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    50. Surgical management of multi-organ visceral tumors in patients with von Hippel-Lindau disease: a single stage approach. J Urol. 2003 Mar; 169(3):895-8. Hwang JJ, Uchio EM, Pavlovich CP, Pautler SE, Libutti SK, Linehan WM, Walther MM. PMID: 12576808.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    51. Diagnostic localization of malignant bladder pheochromocytoma using 6-18F fluorodopamine positron emission tomography. J Urol. 2003 Jan; 169(1):274-5. Hwang JJ, Uchio EM, Patel SV, Linehan WM, Walther MM, Pacak K. PMID: 12478157.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    52. A phase I study of intravesical suramin for the treatment of superficial transitional cell carcinoma of the bladder. J Urol. 2003 Jan; 169(1):357-60. Uchio EM, Linehan WM, Figg WD, Walther MM. PMID: 12478189.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    53. Physiologic studies of male sexual dysfunction in multiple sclerosis. Mult Scler. 2001 Aug; 7(4):249-54. Yang CC, Bowen JD, Kraft GH, Uchio EM, Kromm BG. PMID: 11548985.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    54. Cortical evoked potentials of the dorsal nerve of the clitoris and female sexual dysfunction in multiple sclerosis. J Urol. 2000 Dec; 164(6):2010-3. Yang CC, Bowen JR, Kraft GH, Uchio EM, Kromm BG. PMID: 11061904.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    55. Cortical evoked responses from the perineal nerve. J Urol. 1999 Dec; 162(6):1983-6. Uchio EM, Yang CC, Kromm BG, Bradley WE. PMID: 10569552.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    56. Comparison of intraocular lenses from the standpoint of postoperative glare disability. Acta Ophthalmol Scand. 1995 Apr; 73(2):148-51. Uchio E, Inamura M, Ohno S. PMID: 7656143.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
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