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Uchio, Edward M

TitleAssociate Clinical Professor
InstitutionUniversity of California, Irvine
DepartmentUrology
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-6896
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Calvocoressi L, Uchio E, Ko J, Radhakrishnan K, Aslan M, Concato J. Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density. J Investig Med. 2018 Oct 07. PMID: 30297390.
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    2. Parsons JK, Pinto PA, Pavlovich CP, Uchio E, Kim HL, Nguyen MN, Gulley JL, Jamieson C, Hsu P, Wojtowicz M, Parnes H, Schlom J, Dahut WL, Madan RA, Donahue RN, Chow HS. A Randomized, Double-blind, Phase II Trial of PSA-TRICOM (PROSTVAC) in Patients with Localized Prostate Cancer: The Immunotherapy to Prevent Progression on Active Surveillance Study. Eur Urol Focus. 2018 Sep 06. PMID: 30197041.
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    3. Parekh DJ, Reis IM, Castle EP, Gonzalgo ML, Woods ME, Svatek RS, Weizer AZ, Konety BR, Tollefson M, Krupski TL, Smith ND, Shabsigh A, Barocas DA, Quek ML, Dash A, Kibel AS, Shemanski L, Pruthi RS, Montgomery JS, Weight CJ, Sharp DS, Chang SS, Cookson MS, Gupta GN, Gorbonos A, Uchio EM, Skinner E, Venkatramani V, Soodana-Prakash N, Kendrick K, Smith JA, Thompson IM. Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial. Lancet. 2018 Jun 23; 391(10139):2525-2536. PMID: 29976469.
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    4. Nguyen TB, Ushinsky A, Yang A, Nguyentat M, Fardin S, Uchio E, Lall C, Lee T, Houshyar R. Utility of quantitative apparent diffusion coefficient measurements and normalized apparent diffusion coefficient ratios in the diagnosis of clinically significant peripheral zone prostate cancer. Br J Radiol. 2018 Jun 05; 20180091. PMID: 29869921.
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    5. Desai M, Bidair M, Bhojani N, Trainer A, Arther A, Kramolowsky E, Doumanian L, Elterman D, Kaufman RP, Lingeman J, Krambeck A, Eure G, Badlani G, Plante M, Uchio E, Gin G, Goldenberg L, Paterson R, So A, Humphreys M, Roehrborn C, Kaplan S, Motola J, Zorn KC. Aquablation Procedural Outcomes for BPH in Large Prostates (80-150cc): Initial Experience. BJU Int. 2018 Apr 25. PMID: 29694702.
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    6. Lama DJ, Safiullah S, Patel RM, Lee TK, Balani JP, Zhang L, Okhunov Z, Margulis V, Savage SJ, Uchio E, Landman J. Multi-institutional Evaluation of Upper Urinary Tract Biopsy Using Backloaded Cup Biopsy Forceps, a Nitinol Basket, and Standard Cup Biopsy Forceps. Urology. 2018 Apr 06. PMID: 29630955.
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    7. Albitar M, Ma W, Lund L, Shahbaba B, Uchio E, Feddersen S, Moylan D, Wojno K, Shore N. Prostatectomy-based validation of combined urine and plasma test for predicting high grade prostate cancer. Prostate. 2018 Mar; 78(4):294-299. PMID: 29315679.
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    8. Punnen S, Freedland SJ, Polascik TJ, Loeb S, Risk MC, Savage S, Mathur SC, Uchio E, Dong Y, Silberstein JL. A Multi-Institutional Prospective Trial Confirms Noninvasive Blood Test Maintains Predictive Value in African American Men. J Urol. 2017 Dec 06. PMID: 29223389.
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    9. Spratt DE, Zhang J, Santiago-Jiménez M, Dess RT, Davis JW, Den RB, Dicker AP, Kane CJ, Pollack A, Stoyanova R, Abdollah F, Ross AE, Cole A, Uchio E, Randall JM, Nguyen H, Zhao SG, Mehra R, Glass AG, Lam LLC, Chelliserry J, du Plessis M, Choeurng V, Aranes M, Kolisnik T, Margrave J, Alter J, Jordan J, Buerki C, Yousefi K, Haddad Z, Davicioni E, Trabulsi EJ, Loeb S, Tewari A, Carroll PR, Weinmann S, Schaeffer EM, Klein EA, Karnes RJ, Feng FY, Nguyen PL. Development and Validation of a Novel Integrated Clinical-Genomic Risk Group Classification for Localized Prostate Cancer. J Clin Oncol. 2018 Feb 20; 36(6):581-590. PMID: 29185869.
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    10. Wu Z, Aslan M, Lin H, Ko J, Radhakrishnan K, Wells CK, Uchio E, Concato J. Trajectories of prostate-specific antigen after treatment for prostate cancer. J Investig Med. 2018 Apr; 66(4):768-772. PMID: 29170243.
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    11. Nguyentat M, Ushinsky A, Miranda-Aguirre A, Uchio E, Lall C, Shirkhoda L, Lee T, Green C, Houshyar R. Validation of Prostate Imaging-Reporting and Data System Version 2: A Retrospective Analysis. Curr Probl Diagn Radiol. 2017 Oct 12. PMID: 29126575.
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    12. Li Y, Pham V, Bui M, Song L, Wu C, Walia A, Uchio E, Smith-Liu F, Zi X. Rhodiola rosea L.: an herb with anti-stress, anti-aging, and immunostimulating properties for cancer chemoprevention. Curr Pharmacol Rep. 2017 Dec; 3(6):384-395. PMID: 30393593.
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    13. Albitar M, Ma W, Lund L, Shahbaba B, Uchio E, Feddersen S, Moylan D, Wojno K, Shore N. A Multi-Center Prospective Study to Validate an Algorithm Using Urine and Plasma Biomarkers for Predicting Gleason =3+4 Prostate Cancer on Biopsy. J Cancer. 2017; 8(13):2554-2560. PMID: 28900493.
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    14. Gin GE, Ruel NH, Kardos SV, Sfakianos JP, Uchio E, Lau CS, Yuh BE. Utilization of perioperative systemic chemotherapy in upper tract urothelial carcinoma. Urol Oncol. 2017 05; 35(5):192-200. PMID: 28041996.
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    15. Okhunov Z, Moreira DM, Del Junco M, Abedi G, Lobko II, Kaler KS, Nguyen ND, Youssef R, Uchio E, Kavoussi LR, Landman J. Predictors of Complications After Percutaneous Image-Guided Renal Cryoablation for T1a Renal Cortical Neoplasms. J Endourol. 2017 01; 31(1):7-13. PMID: 27784185.
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    16. Uchio E, Meyskens FL, Wang PH. Deciphering the Effect of Metformin on Prostate Cancer Risk by Ethnicity. Cancer Prev Res (Phila). 2016 Oct; 9(10):777-778. PMID: 27432345.
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    17. Liu Z, Yokoyama NN, Blair CA, Li X, Avizonis D, Wu XR, Uchio E, Youssef R, McClelland M, Pollak M, Zi X. High Sensitivity of an Ha-RAS Transgenic Model of Superficial Bladder Cancer to Metformin Is Associated with ~240-Fold Higher Drug Concentration in Urine than Serum. Mol Cancer Ther. 2016 Mar; 15(3):430-8. PMID: 26921394; PMCID: PMC4783238 [Available on 03/01/17].
    18. Uchio E, Aslan M, Ko J, Wells CK, Radhakrishnan K, Concato J. Velocity and doubling time of prostate-specific antigen: mathematics can matter. J Investig Med. 2016 Feb; 64(2):400-4. PMID: 26767890.
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    19. Jia JB, Houshyar R, Verma S, Uchio E, Lall C. Prostate cancer on computed tomography: A direct comparison with multi-parametric magnetic resonance imaging and tissue pathology. Eur J Radiol. 2016 Jan; 85(1):261-267. PMID: 26526901.
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    20. Yokoyama NN, Denmon A, Uchio EM, Jordan M, Mercola D, Zi X. When Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow? Curr Pharmacol Rep. 2015 Dec 01; 1(6):420-433. PMID: 26756023.
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    21. Kamat AM, Flaig TW, Grossman HB, Konety B, Lamm D, O'Donnell MA, Uchio E, Efstathiou JA, Taylor JA. Expert consensus document: Consensus statement on best practice management regarding the use of intravesical immunotherapy with BCG for bladder cancer. Nat Rev Urol. 2015 04; 12(4):225-35. PMID: 25800393.
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    22. Graham-Steed T, Uchio E, Wells CK, Aslan M, Ko J, Concato J. 'Race' and prostate cancer mortality in equal-access healthcare systems. Am J Med. 2013 Dec; 126(12):1084-8. PMID: 24262722; PMCID: PMC4100601.
    23. Chao HH, Hu S, Ide JS, Uchio E, Zhang S, Rose M, Concato J, Li CS. Effects of androgen deprivation on cerebral morphometry in prostate cancer patients--an exploratory study. PLoS One. 2013; 8(8):e72032. PMID: 23977199; PMCID: PMC3747074.
    24. Vora AA, Marchalik D, Kowalczyk KJ, Nissim H, Bandi G, McGeagh KG, Lynch JH, Ghasemian SR, Verghese M, Venkatesan K, Borges P, Uchio EM, Hwang JJ. Robotic-assisted prostatectomy and open radical retropubic prostatectomy for locally-advanced prostate cancer: multi-institution comparison of oncologic outcomes. Prostate Int. 2013; 1(1):31-6. PMID: 24223399; PMCID: PMC3821519.
    25. Chao HH, Uchio E, Zhang S, Hu S, Bednarski SR, Luo X, Rose M, Concato J, Li CS. Effects of androgen deprivation on brain function in prostate cancer patients - a prospective observational cohort analysis. BMC Cancer. 2012 Aug 27; 12:371. PMID: 22925152; PMCID: PMC3502584.
    26. Guo X, Schmitz JC, Kenney BC, Uchio EM, Kulkarni S, Cha CH. Intermedin is overexpressed in hepatocellular carcinoma and regulates cell proliferation and survival. Cancer Sci. 2012 Aug; 103(8):1474-80. PMID: 22625651.
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    27. Uchio EM, Calderon JS, Hwang JJ. Laparoscopic repair of inguinal cystocele using cystoscopic light test. Urology. 2012 Mar; 79(3):725-7. PMID: 22386428.
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    28. Uchio E, Hoang D, Alam S, McRae M, Kishinevsky A, Narayan D. A novel device for minimally invasive harvest of the sural nerve. Conn Med. 2012 Jan; 76(1):27-31. PMID: 22372176.
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    29. Carlson Scholz JA, Garg R, Compton SR, Allore HG, Zeiss CJ, Uchio EM. Poliomyelitis in MuLV-infected ICR-SCID mice after injection of basement membrane matrix contaminated with lactate dehydrogenase-elevating virus. Comp Med. 2011 Oct; 61(5):404-11. PMID: 22330347; PMCID: PMC3193062.
    30. Uchio EM, Aslan M, Wells CK, Calderone J, Concato J. Impact of biochemical recurrence in prostate cancer among US veterans. Arch Intern Med. 2010 Aug 09; 170(15):1390-5. PMID: 20696967.
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    31. Ramos J, Uchio E, Aslan M, Concato J. Changes in Gleason scores for prostate cancer: what should we expect from a measurement? J Investig Med. 2010 Apr; 58(4):625-8. PMID: 20224436.
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    32. Chao HH, Mayer T, Concato J, Rose MG, Uchio E, Kelly WK. Prostate cancer, comorbidity, and participation in randomized controlled trials of therapy. J Investig Med. 2010 Mar; 58(3):566-8. PMID: 20072029.
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    33. Concato J, Uchio E, Wells CK. Relevance of molecular markers in prostate cancer. Ann Intern Med. 2009 Dec 15; 151(12):894; author reply 894-5. PMID: 20008768.
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    34. Concato J, Jain D, Uchio E, Risch H, Li WW, Wells CK. Molecular markers and death from prostate cancer. Ann Intern Med. 2009 May 05; 150(9):595-603. PMID: 19414838.
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    35. Yoo PS, Sullivan CA, Kiang S, Gao W, Uchio EM, Chung GG, Cha CH. Tissue microarray analysis of 560 patients with colorectal adenocarcinoma: high expression of HuR predicts poor survival. Ann Surg Oncol. 2009 Jan; 16(1):200-7. PMID: 19009247.
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    36. Takizawa BT, Uchio EM, Cohen JJ, Wheeler MA, Weiss RM. Downregulation of survivin is associated with reductions in TNF receptors' mRNA and protein and alterations in nuclear factor kappa B signaling in urothelial cancer cells. Cancer Invest. 2007 Dec; 25(8):678-84. PMID: 18058462.
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    37. Concato J, Jain D, Li WW, Risch HA, Uchio EM, Wells CK. Molecular markers and mortality in prostate cancer. BJU Int. 2007 Dec; 100(6):1259-63. PMID: 17850375.
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    38. Mulkeen AL, Silva T, Yoo PS, Schmitz JC, Uchio E, Chu E, Cha C. Short interfering RNA-mediated gene silencing of vascular endothelial growth factor: effects on cellular proliferation in colon cancer cells. Arch Surg. 2006 Apr; 141(4):367-74; discussion 374. PMID: 16618894.
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    39. Zeeberg BR, Riss J, Kane DW, Bussey KJ, Uchio E, Linehan WM, Barrett JC, Weinstein JN. Mistaken identifiers: gene name errors can be introduced inadvertently when using Excel in bioinformatics. BMC Bioinformatics. 2004 Jun 23; 5:80. PMID: 15214961; PMCID: PMC459209.
    40. Hwang J, Shoaf G, Uchio EM, Watson J, Pacak K, Linehan WM, Walther MM. Laparoscopic management of extra-adrenal pheochromocytoma. J Urol. 2004 Jan; 171(1):72-6. PMID: 14665847.
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    41. Hwang JJ, Dharmawardana PG, Uchio EM, Wynberg J, Phillips JL. Prostate cancer in Klinefelter syndrome during hormonal replacement therapy. Urology. 2003 Nov; 62(5):941. PMID: 14624928.
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    42. Hwang JJ, Uchio EM, Linehan WM, Walther MM. Hereditary kidney cancer. Urol Clin North Am. 2003 Nov; 30(4):831-42. PMID: 14680318.
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    43. Hwang JJ, Uchio EM, Pavlovich CP, Pautler SE, Libutti SK, Linehan WM, Walther MM. Surgical management of multi-organ visceral tumors in patients with von Hippel-Lindau disease: a single stage approach. J Urol. 2003 Mar; 169(3):895-8. PMID: 12576808.
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    44. Hwang JJ, Uchio EM, Patel SV, Linehan WM, Walther MM, Pacak K. Diagnostic localization of malignant bladder pheochromocytoma using 6-18F fluorodopamine positron emission tomography. J Urol. 2003 Jan; 169(1):274-5. PMID: 12478157.
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    45. Uchio EM, Linehan WM, Figg WD, Walther MM. A phase I study of intravesical suramin for the treatment of superficial transitional cell carcinoma of the bladder. J Urol. 2003 Jan; 169(1):357-60. PMID: 12478189.
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