Edward M Uchio

Title(s)Clinical Professor, Urology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-6896
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    1. Author Correction: Oncolytic adenoviral therapy plus pembrolizumab in BCG-unresponsive non-muscle-invasive bladder cancer: the phase 2 CORE-001 trial. Nat Med. 2024 Aug; 30(8):2372. Li R, Shah PH, Stewart TF, Nam JK, Bivalacqua TJ, Lamm DL, Uchio EM, Geynisman DM, Jacob JM, Meeks JJ, Dickstein R, Pearce SM, Kang SH, Jung SI, Kamat AM, Burke JM, Keegan KA, Steinberg GD. PMID: 38890533.
      View in: PubMed   Mentions:    Fields:    
    2. Publisher Correction: Oncolytic adenoviral therapy plus pembrolizumab in BCG-unresponsive non-muscle-invasive bladder cancer: the phase 2 CORE-001 trial. Nat Med. 2024 Aug; 30(8):2377. Li R, Shah PH, Stewart TF, Nam JK, Bivalacqua TJ, Lamm DL, Uchio EM, Geynisman DM, Jacob JM, Meeks JJ, Dickstein R, Pearce SM, Kang SH, Jung SI, Kamat AM, Burke JM, Keegan KA, Steinberg GD. PMID: 38956199.
      View in: PubMed   Mentions:    Fields:    
    3. A Description and Safety Overview of Irreversible Electroporation for Prostate Tissue Ablation in Intermediate-Risk Prostate Cancer Patients: Preliminary Results from the PRESERVE Trial. Cancers (Basel). 2024 Jun 08; 16(12). George AK, Miocinovic R, Patel AR, Lomas DJ, Correa AF, Chen DYT, Rastinehad AR, Schwartz MJ, Uchio EM, Sidana A, Helfand BT, Gahan JC, Yu A, Vourganti S, Barqawi AB, Brisbane WG, Wysock JS, Polascik TJ, McClure TD, Coleman JA. PMID: 38927884; PMCID: PMC11201469.
      View in: PubMed   Mentions:
    4. Oncolytic adenoviral therapy plus pembrolizumab in BCG-unresponsive non-muscle-invasive bladder cancer: the phase 2 CORE-001 trial. Nat Med. 2024 Aug; 30(8):2216-2223. Li R, Shah PH, Stewart TF, Nam JK, Bivalacqua TJ, Lamm DL, Uchio EM, Geynisman DM, Jacob JM, Meeks JJ, Dickstein R, Pearce SM, Kang SH, Jung SI, Kamat AM, Burke JM, Keegan KA, Steinberg GD. PMID: 38844794.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    5. ATPase Copper Transporting Beta (ATP7B) Is a Novel Target for Improving the Therapeutic Efficacy of Docetaxel by Disulfiram/Copper in Human Prostate Cancer. Mol Cancer Ther. 2024 Jun 04; 23(6):854-863. Song L, Nguyen V, Xie J, Jia S, Chang CJ, Uchio E, Zi X. PMID: 38417139; PMCID: PMC11150099.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. Pembrolizumab monotherapy for high-risk non-muscle-invasive bladder cancer without carcinoma in situ and unresponsive to BCG (KEYNOTE-057): a single-arm, multicentre, phase 2 trial. Lancet Oncol. 2024 Jun; 25(6):720-730. Necchi A, Roumiguié M, Kamat AM, Shore ND, Boormans JL, Esen AA, Lebret T, Kandori S, Bajorin DF, Krieger LEM, Niglio SA, Uchio EM, Seo HK, de Wit R, Singer EA, Grivas P, Nishiyama H, Li H, Baranwal P, Van den Sigtenhorst-Fijlstra M, Kapadia E, Kulkarni GS. PMID: 38740030.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    7. Impact of Clinical Factors on 18F-Flotufolastat Detection Rates in Men With Recurrent Prostate Cancer: Exploratory Analysis of the Phase 3 SPOTLIGHT Study. Adv Radiat Oncol. 2024 Aug; 9(8):101532. Lowentritt BH, Jani AB, Helfand BT, Uchio EM, Morris MA, Michalski JM, Chau A, Davis P, Chapin BF, Schuster DM, SPOTLIGHT Study Group. PMID: 39104875; PMCID: PMC11298587.
      View in: PubMed   Mentions:
    8. The Potent Anti-Tumor Effects of Rhodiola Drinking Are Associated with the Inhibition of the mTOR Pathway and Modification of Tumor Metabolism in the UPII-Mutant Ha-Ras Model. Cancers (Basel). 2023 Jun 07; 15(12). Liu Z, Yokoyama NN, Song L, Xie J, Sadeghi Z, Wu YX, Yee S, Wu XR, Wang B, Uchio E, Zi X. PMID: 37370698; PMCID: PMC10296277.
      View in: PubMed   Mentions: 1  
    9. Aquablation Therapy in Large Prostates (80-150 mL) for Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia: Final WATER II 5-Year Clinical Trial Results. J Urol. 2023 07; 210(1):143-153. Bhojani N, Bidair M, Kramolowsky E, Desai M, Doumanian L, Zorn KC, Elterman D, Kaufman RP, Eure G, Badlani G, Plante M, Uchio E, Gin G, Paterson R, So A, Roehrborn C, Motola J, Kaplan S, Humphreys M. PMID: 37115632.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Kawain Inhibits Urinary Bladder Carcinogenesis through Epigenetic Inhibition of LSD1 and Upregulation of H3K4 Methylation. Biomolecules. 2023 03 13; 13(3). Xu X, Tian X, Song L, Xie J, Liao JC, Meeks JJ, Wu XR, Gin GE, Wang B, Uchio E, Zi X. PMID: 36979456; PMCID: PMC10046577.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    11. Kavalactone Kawain Impedes Urothelial Tumorigenesis in UPII-Mutant Ha-Ras Mice via Inhibition of mTOR Signaling and Alteration of Cancer Metabolism. Molecules. 2023 Feb 09; 28(4). Liu Z, Song L, Xie J, Wu XR, Gin GE, Wang B, Uchio E, Zi X. PMID: 36838656; PMCID: PMC9966944.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    12. A Phase 2, Double-blind, Randomized Controlled Trial of PROSTVAC in Prostate Cancer Patients on Active Surveillance. Eur Urol Focus. 2023 May; 9(3):447-454. Parsons JK, Pinto PA, Pavlovich CP, Uchio E, Nguyen MN, Kim HL, Gulley JL, Sater HA, Jamieson C, Hsu CH, Wojtowicz M, House M, Schlom J, Donahue RN, Dahut WL, Madan RA, Bailey S, Centuori S, Bauman JE, Parnes HL, Chow HS. PMID: 36517408; PMCID: PMC10258223.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCTClinical Trials
    13. Prostate cancer immunotherapy: a review of recent advancements with novel treatment methods and efficacy. Am J Clin Exp Urol. 2022; 10(4):210-233. Wang I, Song L, Wang BY, Rezazadeh Kalebasty A, Uchio E, Zi X. PMID: 36051616; PMCID: PMC9428569.
      View in: PubMed   Mentions: 19  
    14. Flavokawain A Reduces Tumor-Initiating Properties and Stemness of Prostate Cancer. Front Oncol. 2022; 12:943846. Song L, Mino M, Yamak J, Nguyen V, Lopez D, Pham V, Fazelpour A, Le V, Fu D, Tippin M, Uchio E, Zi X. PMID: 35912174; PMCID: PMC9326116.
      View in: PubMed   Mentions: 5  
    15. Use of immunotherapy in clinical management of genitourinary cancers - a review. Cancer Treat Res Commun. 2022; 31:100564. Mar N, Uchio E, Kalebasty AR. PMID: 35472699.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    16. Chemoprevention of Urothelial Cell Carcinoma Tumorigenesis by Dietary Flavokawain A in UPII-Mutant Ha-ras Transgenic Mice. Pharmaceutics. 2022 Feb 24; 14(3). Liu Z, Song L, Xie J, Simoneau AR, Uchio E, Zi X. PMID: 35335874; PMCID: PMC8955676.
      View in: PubMed   Mentions: 8  
    17. Comparison of Perioperative Outcomes for Radical Nephrectomy Based on Surgical Approach for Masses Greater Than 10 cm. J Endourol. 2021 12; 35(12):1785-1792. Grimaud LW, Chen FV, Chang J, Ziogas A, Sfakianos JP, Badani KK, Uchio EM, Anton-Culver H, Gin GE. PMID: 34148404.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Aquablation therapy in large prostates (80-150 cc) for lower urinary tract symptoms due to benign prostatic hyperplasia: WATER II 3-year trial results. BJUI Compass. 2022 Mar; 3(2):130-138. Zorn KC, Bidair M, Trainer A, Arther A, Kramolowsky E, Desai M, Doumanian L, Elterman D, Kaufman RP, Lingeman J, Krambeck A, Eure G, Badlani G, Plante M, Uchio E, Gin G, Goldenberg SL, Paterson R, So A, Humphreys M, Roehrborn C, Kaplan S, Motola J, Bhojani N. PMID: 35474721; PMCID: PMC8988689.
      View in: PubMed   Mentions: 8  
    19. A phase II study of docetaxel plus lycopene in metastatic castrate resistant prostate cancer. Biomed Pharmacother. 2021 Nov; 143:112226. Zhuang E, Uchio E, Lilly M, Zi X, Fruehauf JP. PMID: 34649352; PMCID: PMC9886492.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    20. Kava root extracts hinder prostate cancer development and tumorigenesis by involvement of dual inhibition of MAO-A and LSD1. J Transl Genet Genom. 2021; 5:163-172. Li X, Song L, Xu S, Tippin M, Meng S, Xie J, Uchio E, Zi X. PMID: 34368644; PMCID: PMC8341175.
      View in: PubMed   Mentions: 4  
    21. Pembrolizumab monotherapy for the treatment of high-risk non-muscle-invasive bladder cancer unresponsive to BCG (KEYNOTE-057): an open-label, single-arm, multicentre, phase 2 study. Lancet Oncol. 2021 07; 22(7):919-930. Balar AV, Kamat AM, Kulkarni GS, Uchio EM, Boormans JL, Roumiguié M, Krieger LEM, Singer EA, Bajorin DF, Grivas P, Seo HK, Nishiyama H, Konety BR, Li H, Nam K, Kapadia E, Frenkl T, de Wit R. PMID: 34051177.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansCTClinical Trials
    22. Management of Advanced Prostate Cancer in Clinical Practice: Real-World Answers to Challenging Dilemmas. JCO Oncol Pract. 2020 12; 16(12):783-789. Mar N, Kalebasty AR, Uchio EM. PMID: 33301698.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. A 3D-2D Hybrid U-Net Convolutional Neural Network Approach to Prostate Organ Segmentation of Multiparametric MRI. AJR Am J Roentgenol. 2021 01; 216(1):111-116. Ushinsky A, Bardis M, Glavis-Bloom J, Uchio E, Chantaduly C, Nguyentat M, Chow D, Chang PD, Houshyar R. PMID: 32812797.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    24. Aquablation for benign prostatic hyperplasia in large prostates (80-150 cc): 2-year results. Can J Urol. 2020 04; 27(2):10147-10153. Desai M, Bidair M, Bhojani N, Trainer A, Arther A, Kramolowsky E, Doumanian L, Elterman D, Kaufman RP, Lingeman J, Krambeck A, Eure G, Badlani G, Plante M, Uchio E, Gin G, Goldenberg L, Paterson R, So A, Humphreys MR, Roehrborn CG, Kaplan S, Motola J, Zorn KC. PMID: 32333733.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    25. Veterans Affairs Cooperative Studies Program Study #553: Chemotherapy After Prostatectomy for High-risk Prostate Carcinoma: A Phase III Randomized Study. Eur Urol. 2020 05; 77(5):563-572. Lin DW, Shih MC, Aronson W, Basler J, Beer TM, Brophy M, Cooperberg M, Garzotto M, Kelly WK, Lee K, McGuire V, Wang Y, Lu Y, Markle V, Nseyo U, Ringer R, Savage SJ, Sinnott P, Uchio E, Yang CC, Montgomery RB. PMID: 31924316.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    26. Predictors of Recurrence, and Progression-Free and Overall Survival following Open versus Robotic Radical Cystectomy: Analysis from the RAZOR Trial with a 3-Year Followup. J Urol. 2020 03; 203(3):522-529. Venkatramani V, Reis IM, Castle EP, Gonzalgo ML, Woods ME, Svatek RS, Weizer AZ, Konety BR, Tollefson M, Krupski TL, Smith ND, Shabsigh A, Barocas DA, Quek ML, Dash A, Kibel AS, Pruthi RS, Montgomery JS, Weight CJ, Sharp DS, Chang SS, Cookson MS, Gupta GN, Gorbonos A, Uchio EM, Skinner E, Soodana-Prakash N, Becerra MF, Swain S, Kendrick K, Smith JA, Thompson IM, Parekh DJ. PMID: 31549935; PMCID: PMC7487279.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    27. PI-RADS Version 2 Is an Excellent Screening Tool for Clinically Significant Prostate Cancer as Designated by the Validated International Society of Urological Pathology Criteria: A Retrospective Analysis. Curr Probl Diagn Radiol. 2020 Nov - Dec; 49(6):407-411. Daun M, Fardin S, Ushinsky A, Batra S, Nguyentat M, Lee T, Uchio E, Lall C, Houshyar R. PMID: 31350101.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    28. Aquablation for Benign Prostatic Hyperplasia in Large Prostates (80-150 cc): 1-Year Results. Urology. 2019 Jul; 129:1-7. Bhojani N, Bidair M, Zorn KC, Trainer A, Arther A, Kramolowsky E, Doumanian L, Elterman D, Kaufman RP, Lingeman J, Krambeck A, Eure G, Badlani G, Plante M, Uchio E, Gin G, Goldenberg L, Paterson R, So A, Humphreys M, Kaplan S, Motola J, Desai M, Roehrborn C. PMID: 31059728.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    29. Aquablation for benign prostatic hyperplasia in large prostates (80-150 mL): 6-month results from the WATER II trial. BJU Int. 2019 08; 124(2):321-328. Desai M, Bidair M, Zorn KC, Trainer A, Arther A, Kramolowsky E, Doumanian L, Elterman D, Kaufman RP, Lingeman J, Krambeck A, Eure G, Badlani G, Plante M, Uchio E, Gin G, Goldenberg L, Paterson R, So A, Humphreys M, Roehrborn C, Kaplan S, Motola J, Bhojani N. PMID: 30734990.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    30. Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation. Cell Commun Signal. 2019 03 18; 17(1):25. Li X, Pham V, Tippin M, Fu D, Rendon R, Song L, Uchio E, Hoang BH, Zi X. PMID: 30885218; PMCID: PMC6423783.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    31. Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density. J Investig Med. 2018 12; 66(8):1142-1146. Calvocoressi L, Uchio E, Ko J, Radhakrishnan K, Aslan M, Concato J. PMID: 30297390.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    32. A Randomized, Double-blind, Phase II Trial of PSA-TRICOM (PROSTVAC) in Patients with Localized Prostate Cancer: The Immunotherapy to Prevent Progression on Active Surveillance Study. Eur Urol Focus. 2018 09; 4(5):636-638. Parsons JK, Pinto PA, Pavlovich CP, Uchio E, Kim HL, Nguyen MN, Gulley JL, Jamieson C, Hsu P, Wojtowicz M, Parnes H, Schlom J, Dahut WL, Madan RA, Donahue RN, Chow HS. PMID: 30197041; PMCID: PMC7524340.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    33. Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial. Lancet. 2018 06 23; 391(10139):2525-2536. Parekh DJ, Reis IM, Castle EP, Gonzalgo ML, Woods ME, Svatek RS, Weizer AZ, Konety BR, Tollefson M, Krupski TL, Smith ND, Shabsigh A, Barocas DA, Quek ML, Dash A, Kibel AS, Shemanski L, Pruthi RS, Montgomery JS, Weight CJ, Sharp DS, Chang SS, Cookson MS, Gupta GN, Gorbonos A, Uchio EM, Skinner E, Venkatramani V, Soodana-Prakash N, Kendrick K, Smith JA, Thompson IM. PMID: 29976469.
      View in: PubMed   Mentions: 191     Fields:    Translation:HumansCTClinical Trials
    34. Utility of quantitative apparent diffusion coefficient measurements and normalized apparent diffusion coefficient ratios in the diagnosis of clinically significant peripheral zone prostate cancer. Br J Radiol. 2018 Jul; 91(1088):20180091. Nguyen TB, Ushinsky A, Yang A, Nguyentat M, Fardin S, Uchio E, Lall C, Lee T, Houshyar R. PMID: 29869921; PMCID: PMC6209473.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    35. WATER II (80-150 mL) procedural outcomes. BJU Int. 2019 01; 123(1):106-112. Desai M, Bidair M, Bhojani N, Trainer A, Arther A, Kramolowsky E, Doumanian L, Elterman D, Kaufman RP, Lingeman J, Krambeck A, Eure G, Badlani G, Plante M, Uchio E, Gin G, Goldenberg L, Paterson R, So A, Humphreys M, Roehrborn C, Kaplan S, Motola J, Zorn KC. PMID: 29694702.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    36. Multi-institutional Evaluation of Upper Urinary Tract Biopsy Using Backloaded Cup Biopsy Forceps, a Nitinol Basket, and Standard Cup Biopsy Forceps. Urology. 2018 Jul; 117:89-94. Lama DJ, Safiullah S, Patel RM, Lee TK, Balani JP, Zhang L, Okhunov Z, Margulis V, Savage SJ, Uchio E, Landman J. PMID: 29630955; PMCID: PMC6214198.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    37. Prostatectomy-based validation of combined urine and plasma test for predicting high grade prostate cancer. Prostate. 2018 03; 78(4):294-299. Albitar M, Ma W, Lund L, Shahbaba B, Uchio E, Feddersen S, Moylan D, Wojno K, Shore N. PMID: 29315679.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    38. A Multi-Institutional Prospective Trial Confirms Noninvasive Blood Test Maintains Predictive Value in African American Men. J Urol. 2018 06; 199(6):1459-1463. Punnen S, Freedland SJ, Polascik TJ, Loeb S, Risk MC, Savage S, Mathur SC, Uchio E, Dong Y, Silberstein JL. PMID: 29223389.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    39. Development and Validation of a Novel Integrated Clinical-Genomic Risk Group Classification for Localized Prostate Cancer. J Clin Oncol. 2018 02 20; 36(6):581-590. Spratt DE, Zhang J, Santiago-Jiménez M, Dess RT, Davis JW, Den RB, Dicker AP, Kane CJ, Pollack A, Stoyanova R, Abdollah F, Ross AE, Cole A, Uchio E, Randall JM, Nguyen H, Zhao SG, Mehra R, Glass AG, Lam LLC, Chelliserry J, du Plessis M, Choeurng V, Aranes M, Kolisnik T, Margrave J, Alter J, Jordan J, Buerki C, Yousefi K, Haddad Z, Davicioni E, Trabulsi EJ, Loeb S, Tewari A, Carroll PR, Weinmann S, Schaeffer EM, Klein EA, Karnes RJ, Feng FY, Nguyen PL. PMID: 29185869; PMCID: PMC6530900.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    40. Trajectories of prostate-specific antigen after treatment for prostate cancer. J Investig Med. 2018 04; 66(4):768-772. Wu Z, Aslan M, Lin H, Ko J, Radhakrishnan K, Wells CK, Uchio E, Concato J. PMID: 29170243.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. Validation of Prostate Imaging-Reporting and Data System Version 2: A Retrospective Analysis. Curr Probl Diagn Radiol. 2018 Nov; 47(6):404-409. Nguyentat M, Ushinsky A, Miranda-Aguirre A, Uchio E, Lall C, Shirkhoda L, Lee T, Green C, Houshyar R. PMID: 29126575; PMCID: PMC6193550.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    42. Rhodiola rosea L.: an herb with anti-stress, anti-aging, and immunostimulating properties for cancer chemoprevention. Curr Pharmacol Rep. 2017 Dec; 3(6):384-395. Li Y, Pham V, Bui M, Song L, Wu C, Walia A, Uchio E, Smith-Liu F, Zi X. PMID: 30393593; PMCID: PMC6208354.
      View in: PubMed   Mentions: 28  
    43. A Multi-Center Prospective Study to Validate an Algorithm Using Urine and Plasma Biomarkers for Predicting Gleason ≥3+4 Prostate Cancer on Biopsy. J Cancer. 2017; 8(13):2554-2560. Albitar M, Ma W, Lund L, Shahbaba B, Uchio E, Feddersen S, Moylan D, Wojno K, Shore N. PMID: 28900493; PMCID: PMC5595085.
      View in: PubMed   Mentions:
    44. Utilization of perioperative systemic chemotherapy in upper tract urothelial carcinoma. Urol Oncol. 2017 05; 35(5):192-200. Gin GE, Ruel NH, Kardos SV, Sfakianos JP, Uchio E, Lau CS, Yuh BE. PMID: 28041996.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    45. Predictors of Complications After Percutaneous Image-Guided Renal Cryoablation for T1a Renal Cortical Neoplasms. J Endourol. 2017 01; 31(1):7-13. Okhunov Z, Moreira DM, Del Junco M, Abedi G, Lobko II, Kaler KS, Nguyen ND, Youssef R, Uchio E, Kavoussi LR, Landman J. PMID: 27784185.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    46. Deciphering the Effect of Metformin on Prostate Cancer Risk by Ethnicity. Cancer Prev Res (Phila). 2016 10; 9(10):777-778. Uchio E, Meyskens FL, Wang PH. PMID: 27432345; PMCID: PMC5098894.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    47. High Sensitivity of an Ha-RAS Transgenic Model of Superficial Bladder Cancer to Metformin Is Associated with ∼240-Fold Higher Drug Concentration in Urine than Serum. Mol Cancer Ther. 2016 Mar; 15(3):430-8. Liu Z, Yokoyama NN, Blair CA, Li X, Avizonis D, Wu XR, Uchio E, Youssef R, McClelland M, Pollak M, Zi X. PMID: 26921394; PMCID: PMC4783238.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    48. Velocity and doubling time of prostate-specific antigen: mathematics can matter. J Investig Med. 2016 Feb; 64(2):400-4. Uchio E, Aslan M, Ko J, Wells CK, Radhakrishnan K, Concato J. PMID: 26767890.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    49. Prostate cancer on computed tomography: A direct comparison with multi-parametric magnetic resonance imaging and tissue pathology. Eur J Radiol. 2016 Jan; 85(1):261-267. Jia JB, Houshyar R, Verma S, Uchio E, Lall C. PMID: 26526901.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    50. When Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow? Curr Pharmacol Rep. 2015 Dec 01; 1(6):420-433. Yokoyama NN, Denmon A, Uchio EM, Jordan M, Mercola D, Zi X. PMID: 26756023; PMCID: PMC4705552.
      View in: PubMed   Mentions: 7  
    51. Expert consensus document: Consensus statement on best practice management regarding the use of intravesical immunotherapy with BCG for bladder cancer. Nat Rev Urol. 2015 04; 12(4):225-35. Kamat AM, Flaig TW, Grossman HB, Konety B, Lamm D, O'Donnell MA, Uchio E, Efstathiou JA, Taylor JA. PMID: 25800393.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    52. 'Race' and prostate cancer mortality in equal-access healthcare systems. Am J Med. 2013 Dec; 126(12):1084-8. Graham-Steed T, Uchio E, Wells CK, Aslan M, Ko J, Concato J. PMID: 24262722; PMCID: PMC4100601.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    53. Effects of androgen deprivation on cerebral morphometry in prostate cancer patients--an exploratory study. PLoS One. 2013; 8(8):e72032. Chao HH, Hu S, Ide JS, Uchio E, Zhang S, Rose M, Concato J, Li CS. PMID: 23977199; PMCID: PMC3747074.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    54. Robotic-assisted prostatectomy and open radical retropubic prostatectomy for locally-advanced prostate cancer: multi-institution comparison of oncologic outcomes. Prostate Int. 2013; 1(1):31-6. Vora AA, Marchalik D, Kowalczyk KJ, Nissim H, Bandi G, McGeagh KG, Lynch JH, Ghasemian SR, Verghese M, Venkatesan K, Borges P, Uchio EM, Hwang JJ. PMID: 24223399; PMCID: PMC3821519.
      View in: PubMed   Mentions: 9  
    55. Effects of androgen deprivation on brain function in prostate cancer patients - a prospective observational cohort analysis. BMC Cancer. 2012 Aug 27; 12:371. Chao HH, Uchio E, Zhang S, Hu S, Bednarski SR, Luo X, Rose M, Concato J, Li CS. PMID: 22925152; PMCID: PMC3502584.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    56. Intermedin is overexpressed in hepatocellular carcinoma and regulates cell proliferation and survival. Cancer Sci. 2012 Aug; 103(8):1474-80. Guo X, Schmitz JC, Kenney BC, Uchio EM, Kulkarni S, Cha CH. PMID: 22625651; PMCID: PMC7659195.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    57. Laparoscopic repair of inguinal cystocele using cystoscopic light test. Urology. 2012 Mar; 79(3):725-7. Uchio EM, Calderon JS, Hwang JJ. PMID: 22386428.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    58. A novel device for minimally invasive harvest of the sural nerve. Conn Med. 2012 Jan; 76(1):27-31. Uchio E, Hoang D, Alam S, McRae M, Kishinevsky A, Narayan D. PMID: 22372176.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    59. Poliomyelitis in MuLV-infected ICR-SCID mice after injection of basement membrane matrix contaminated with lactate dehydrogenase-elevating virus. Comp Med. 2011 Oct; 61(5):404-11. Carlson Scholz JA, Garg R, Compton SR, Allore HG, Zeiss CJ, Uchio EM. PMID: 22330347; PMCID: PMC3193062.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    60. Impact of biochemical recurrence in prostate cancer among US veterans. Arch Intern Med. 2010 Aug 09; 170(15):1390-5. Uchio EM, Aslan M, Wells CK, Calderone J, Concato J. PMID: 20696967.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    61. Changes in Gleason scores for prostate cancer: what should we expect from a measurement? J Investig Med. 2010 Apr; 58(4):625-8. Ramos J, Uchio E, Aslan M, Concato J. PMID: 20224436.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    62. Prostate cancer, comorbidity, and participation in randomized controlled trials of therapy. J Investig Med. 2010 Mar; 58(3):566-8. Chao HH, Mayer T, Concato J, Rose MG, Uchio E, Kelly WK. PMID: 20072029.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    63. Relevance of molecular markers in prostate cancer. Ann Intern Med. 2009 Dec 15; 151(12):894; author reply 894-5. Concato J, Uchio E, Wells CK. PMID: 20008768.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    64. Molecular markers and death from prostate cancer. Ann Intern Med. 2009 May 05; 150(9):595-603. Concato J, Jain D, Uchio E, Risch H, Li WW, Wells CK. PMID: 19414838.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    65. Tissue microarray analysis of 560 patients with colorectal adenocarcinoma: high expression of HuR predicts poor survival. Ann Surg Oncol. 2009 Jan; 16(1):200-7. Yoo PS, Sullivan CA, Kiang S, Gao W, Uchio EM, Chung GG, Cha CH. PMID: 19009247.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    66. Downregulation of survivin is associated with reductions in TNF receptors' mRNA and protein and alterations in nuclear factor kappa B signaling in urothelial cancer cells. Cancer Invest. 2007 Dec; 25(8):678-84. Takizawa BT, Uchio EM, Cohen JJ, Wheeler MA, Weiss RM. PMID: 18058462.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    67. Molecular markers and mortality in prostate cancer. BJU Int. 2007 Dec; 100(6):1259-63. Concato J, Jain D, Li WW, Risch HA, Uchio EM, Wells CK. PMID: 17850375.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    68. Short interfering RNA-mediated gene silencing of vascular endothelial growth factor: effects on cellular proliferation in colon cancer cells. Arch Surg. 2006 Apr; 141(4):367-74; discussion 374. Mulkeen AL, Silva T, Yoo PS, Schmitz JC, Uchio E, Chu E, Cha C. PMID: 16618894.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    69. Mistaken identifiers: gene name errors can be introduced inadvertently when using Excel in bioinformatics. BMC Bioinformatics. 2004 Jun 23; 5:80. Zeeberg BR, Riss J, Kane DW, Bussey KJ, Uchio E, Linehan WM, Barrett JC, Weinstein JN. PMID: 15214961; PMCID: PMC459209.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    70. Laparoscopic management of extra-adrenal pheochromocytoma. J Urol. 2004 Jan; 171(1):72-6. Hwang J, Shoaf G, Uchio EM, Watson J, Pacak K, Linehan WM, Walther MM. PMID: 14665847.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    71. Prostate cancer in Klinefelter syndrome during hormonal replacement therapy. Urology. 2003 Nov; 62(5):941. Hwang JJ, Dharmawardana PG, Uchio EM, Wynberg J, Phillips JL. PMID: 14624928.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    72. Hereditary kidney cancer. Urol Clin North Am. 2003 Nov; 30(4):831-42. Hwang JJ, Uchio EM, Linehan WM, Walther MM. PMID: 14680318.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    73. Surgical management of multi-organ visceral tumors in patients with von Hippel-Lindau disease: a single stage approach. J Urol. 2003 Mar; 169(3):895-8. Hwang JJ, Uchio EM, Pavlovich CP, Pautler SE, Libutti SK, Linehan WM, Walther MM. PMID: 12576808.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    74. Diagnostic localization of malignant bladder pheochromocytoma using 6-18F fluorodopamine positron emission tomography. J Urol. 2003 Jan; 169(1):274-5. Hwang JJ, Uchio EM, Patel SV, Linehan WM, Walther MM, Pacak K. PMID: 12478157.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    75. A phase I study of intravesical suramin for the treatment of superficial transitional cell carcinoma of the bladder. J Urol. 2003 Jan; 169(1):357-60. Uchio EM, Linehan WM, Figg WD, Walther MM. PMID: 12478189.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    76. Physiologic studies of male sexual dysfunction in multiple sclerosis. Mult Scler. 2001 Aug; 7(4):249-54. Yang CC, Bowen JD, Kraft GH, Uchio EM, Kromm BG. PMID: 11548985.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    77. Cortical evoked potentials of the dorsal nerve of the clitoris and female sexual dysfunction in multiple sclerosis. J Urol. 2000 Dec; 164(6):2010-3. Yang CC, Bowen JR, Kraft GH, Uchio EM, Kromm BG. PMID: 11061904.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    78. Cortical evoked responses from the perineal nerve. J Urol. 1999 Dec; 162(6):1983-6. Uchio EM, Yang CC, Kromm BG, Bradley WE. PMID: 10569552.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    79. Comparison of intraocular lenses from the standpoint of postoperative glare disability. Acta Ophthalmol Scand. 1995 Apr; 73(2):148-51. Uchio E, Inamura M, Ohno S. PMID: 7656143.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    80. [Survival rate of patients with diabetic retinopathy after vitreous surgery]. Nippon Ganka Gakkai Zasshi. 1994 Oct; 98(10):989-93. Matsumoto T, Uchio E, Gotoh K, Saeki K, Ohno S. PMID: 7976836.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
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