Christy L Hom

Title(s)Associate Clinical Professor, Psychiatry
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-5902
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    Collapse Biography 
    Collapse Education and Training
    University of Michigan, Ann ArborPh.D.04/2002Clinical Psychology
    University of California, Los AngelesB.A.03/1994Psychology
    Children's Hospital of Orange County12/2003Post-doctoral fellowship
    Collapse Awards and Honors
    American Board of Pediatric Neuropsychology2014Diplomate
    American Academy of Clinical Neuropsychology2013Member
    American Psychological Association2004Member
    National Academy of Neuropsychology2013Member

    Collapse Overview 
    Collapse Overview
    Dr. Christy Hom is a clinical psychologist and board certified pediatric neuropsychologist. She specializes in the assessment of neurodevelopmental disorders, developmental disabilities, traumatic brain injury, seizure disorders, and psychiatric disorders. Her research studies have focused on the structural and functional differences in neural circuitry between adolescents who have and have not experienced maltreatment, cognitive decline in older adults, multisensory treatment for children with Autism , and Alzheimer's disease in persons with Down Syndrome.

    Collapse Research 
    Collapse Research Activities and Funding
    Effects of Childhood Maltreatment on Neurocircuitry in Adolescent Depression
    NIH R01MH108155Aug 1, 2017 - Mar 31, 2023
    Role: Co-Investigator
    Biomarkers of Alzheimer's Disease in Adults with Down Syndrome
    NIH U01AG051412Sep 30, 2015 - Apr 30, 2020
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Neurofilament light chain concentration mediates the association between regional medial temporal lobe structure and memory in adults with Down syndrome. Alzheimers Dement (Amst). 2024 Jan-Mar; 16(1):e12542. DiProspero N, Sathishkumar M, Janecek J, Smith A, McMillan L, Petersen M, Tustison N, Keator DB, Doran E, Hom CL, Nguyen D, Andrews H, Krinsky-McHale S, Brickman AM, Rosas HD, Lai F, Head E, Mapstone M, Silverman W, Lott IT, O'Bryant S, Yassa MA. PMID: 38348178; PMCID: PMC10859879.
      View in: PubMed   Mentions:
    2. Pathways linking pulse pressure to dementia in adults with Down syndrome. medRxiv. 2023 Oct 26. Rizvi B, Lao PJ, Sathishkumar M, Taylor L, Queder N, McMillan L, Edwards N, Keator DB, Doran E, Hom C, Nguyen D, Rosas HD, Lai F, Schupf N, Gutierrez J, Silverman W, Lott IT, Mapstone M, Wilcock DM, Head E, Yassa MA, Brickman AM. PMID: 37961444; PMCID: PMC10635215.
      View in: PubMed   Mentions:
    3. Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome. Alzheimers Dement. 2024 Feb; 20(2):1038-1049. Gorijala P, Aslam MM, Dang LT, Xicota L, Fernandez MV, Sung YJ, Fan KH, Feingold E, Surace EI, Chhatwal JP, Hom CL, Dominantly Inherited Alzheimer Network (DIAN), the Alzheimer's Disease Neuroimaging Initiative (ADNI, NIA-LOAD family study, for the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS) Investigator, Hartley SL, Hassenstab J, Perrin RJ, Mapstone M, Zaman SH, Ances BM, Kamboh MI, Lee JH, Cruchaga C. PMID: 37855447.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Timing of Alzheimer's Disease by Intellectual Disability Level in Down Syndrome. J Alzheimers Dis. 2023; 95(1):213-225. Hartley SL, Fleming V, Schworer EK, Peven J, Handen BL, Krinsky-McHale S, Hom C, Lee L, Tudorascu DL, Laymon C, Minhas D, Luo W, Cohen A, Zaman S, Ances BM, Mapstone M, Head E, Lai F, Rosas HD, Klunk W, Christian B, Alzheimer Biomarker Consortium-Down Syndrome. PMID: 37482997; PMCID: PMC10578224.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. A modified Cued Recall Test for detecting prodromal AD in adults with Down syndrome. Alzheimers Dement (Amst). 2022; 14(1):e12361. Krinsky-McHale SJ, Hartley S, Hom C, Pulsifer M, Clare ICH, Handen BL, Lott IT, Schupf N, Silverman W, Alzheimer's Biomarker Consortium—Down Syndrome (ABC-DS) Investigators. PMID: 36212742; PMCID: PMC9527593.
      View in: PubMed   Mentions: 3  
    6. Cognitive outcome measures for tracking Alzheimer's disease in Down syndrome. Int Rev Res Dev Disabil. 2022; 62:227-263. Fleming V, Hom CL, Clare ICH, Hurd-Thomas SL, Krinsky-McHale S, Handen B, Hartley SL. PMID: 37396708; PMCID: PMC10312212.
      View in: PubMed   Mentions: 1  
    7. Correction: Hom et al. Cognitive Function during the Prodromal Stage of Alzheimer's Disease in Down Syndrome: Comparing Models. BrainSci. 2021, 11, 1220. Brain Sci. 2022 Jul 15; 12(7). Hom CL, Kirby KA, Ricks-Oddie J, Keator DB, Krinsky-McHale SJ, Pulsifer MB, Rosas HD, Lai F, Schupf N, Lott IT, Silverman W. PMID: 35884766; PMCID: PMC9313374.
      View in: PubMed   Mentions:
    8. Joint-label fusion brain atlases for dementia research in Down syndrome. Alzheimers Dement (Amst). 2022; 14(1):e12324. Queder N, Phelan MJ, Taylor L, Tustison N, Doran E, Hom C, Nguyen D, Lai F, Pulsifer M, Price J, Kreisl WC, Rosas HD, Krinsky-McHale S, Brickman AM, Yassa MA, Schupf N, Silverman W, Lott IT, Head E, Mapstone M, Keator DB, Alzheimer's Biomarkers Consortium. PMID: 35634535; PMCID: PMC9131930.
      View in: PubMed   Mentions: 1  
    9. Impact of the COVID-19 pandemic on daily life, mood, and behavior of adults with Down syndrome. Disabil Health J. 2022 07; 15(3):101278. Hartley SL, Fleming V, Piro-Gambetti B, Cohen A, Ances BM, Yassa MA, Brickman AM, Handen BL, Head E, Mapstone M, Christian BT, Lott IT, Doran E, Zaman S, Krinsky-McHale S, Schmitt FA, Hom C, Schupf N, ABC-DS Group. PMID: 35256308; PMCID: PMC8849846.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    10. Cognitive Function during the Prodromal Stage of Alzheimer's Disease in Down Syndrome: Comparing Models. Brain Sci. 2021 Sep 16; 11(9). Hom CL, Kirby KA, Ricks-Oddie J, Keator DB, Krinsky-McHale SJ, Pulsifer MB, Rosas HD, Lai F, Schupf N, Lott IT, Silverman W. PMID: 34573242; PMCID: PMC8471085.
      View in: PubMed   Mentions: 5  
    11. Cognitive and Behavioral Domains That Reliably Differentiate Normal Aging and Dementia in Down Syndrome. Brain Sci. 2021 Aug 25; 11(9). Harp JP, Koehl LM, Pelt KLV, Hom CL, Doran E, Head E, Lott IT, Schmitt FA. PMID: 34573150; PMCID: PMC8468129.
      View in: PubMed   Mentions: 3  
    12. Cognitive assessment using the Rapid Assessment for Developmental Disabilities, Second Edition (RADD-2). J Intellect Disabil Res. 2021 09; 65(9):831-848. Hom CL, Walsh D, Fernandez G, Tournay A, Touchette P, Lott IT. PMID: 34196436.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Evaluation of the National Task Group-Early Detection Screen for Dementia: Sensitivity to 'mild cognitive impairment' in adults with Down syndrome. J Appl Res Intellect Disabil. 2021 May; 34(3):905-915. Silverman W, Krinsky-McHale SJ, Lai F, Diana Rosas H, Hom C, Doran E, Pulsifer M, Lott I, Schupf N, Alzheimer’s Disease in Down Syndrome (ADDS) Consortium. PMID: 33314467; PMCID: PMC8356176.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    14. Brain amyloid and the transition to dementia in Down syndrome. Alzheimers Dement (Amst). 2020; 12(1):e12126. Keator DB, Doran E, Taylor L, Phelan MJ, Hom C, Tseung K, van Erp TGM, Potkin SG, Brickman AM, Rosas DH, Yassa MA, Silverman W, Lott IT. PMID: 33204814; PMCID: PMC7656170.
      View in: PubMed   Mentions: 5  
    15. Alzheimer-related altered white matter microstructural integrity in Down syndrome: A model for sporadic AD? Alzheimers Dement (Amst). 2020; 12(1):e12040. Rosas HD, Hsu E, Mercaldo ND, Lai F, Pulsifer M, Keator D, Brickman AM, Price J, Yassa M, Hom C, Krinsky-McHale SJ, Silverman W, Lott I, Schupf N. PMID: 33204811; PMCID: PMC7648416.
      View in: PubMed   Mentions: 8  
    16. Language skills as a predictor of cognitive decline in adults with Down syndrome. Alzheimers Dement (Amst). 2020; 12(1):e12080. Pulsifer MB, Evans CL, Hom C, Krinsky-McHale SJ, Silverman W, Lai F, Lott I, Schupf N, Wen J, Rosas HD. PMID: 32875055; PMCID: PMC7447889.
      View in: PubMed   Mentions: 10  
    17. Down syndrome: Distribution of brain amyloid in mild cognitive impairment. Alzheimers Dement (Amst). 2020; 12(1):e12013. Keator DB, Phelan MJ, Taylor L, Doran E, Krinsky-McHale S, Price J, Ballard EE, Kreisl WC, Hom C, Nguyen D, Pulsifer M, Lai F, Rosas DH, Brickman AM, Schupf N, Yassa MA, Silverman W, Lott IT. PMID: 32435685; PMCID: PMC7233421.
      View in: PubMed   Mentions: 8  
    18. Self-concept in children with Down syndrome. Am J Med Genet A. 2014 Aug; 164A(8):1891-8. Saha S, Doran E, Osann KE, Hom C, Movsesyan N, Rosa DD, Tournay A, Lott IT. PMID: 24838927; PMCID: PMC5800412.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. The relationship between living arrangement and adherence to antiepileptic medications among individuals with developmental disabilities. J Intellect Disabil Res. 2015 Jan; 59(1):48-54. Hom CL, Touchette P, Nguyen V, Fernandez G, Tournay A, Plon L, Himber P, Lott IT. PMID: 24612032.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. Effects of equal and unequal reinforcer duration during functional analysis. J Appl Behav Anal. 1996; 29(1):117-20. Fisher WW, Piazza CC, Chiang CL. PMID: 8881352; PMCID: PMC1279881.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
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