Asuka Eguchi

Title(s)Assistant Professor, Physiology and Biophysics
SchoolSchool of Medicine
ORCID ORCID Icon0000-0003-3010-0275 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Alabama in HuntsvilleB.S.2010Biology
    University of Wisconsin-MadisonPh.D.2016Cellular and Molecular Biology
    Stanford UniversityPostdoctoral Fellow2023Disease Modeling
    Collapse Awards and Honors
    24CDA12594242024  - 2027American Heart Association Career Development Award
    HL1694132023  - 2028K01 Career Development Award
    9646972022  - 2025Muscular Dystrophy Association Development Grant

    Collapse Overview 
    Collapse Overview
    Affiliations:
    Sue and Bill Gross Stem Cell Research Center
    Edwards Lifesciences Foundation Cardiovascular Innovation and Research Center
    Muscle Biology and Disease Research Center
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. Proc Natl Acad Sci U S A. 2023 02 07; 120(6):e2209967120. Eguchi A, Gonzalez AFGS, Torres-Bigio SI, Koleckar K, Birnbaum F, Zhang JZ, Wang VY, Wu JC, Artandi SE, Blau HM. PMID: 36719921; PMCID: PMC9963063.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    2. Tamoxifen treatment ameliorates contractile dysfunction of Duchenne muscular dystrophy stem cell-derived cardiomyocytes on bioengineered substrates. NPJ Regen Med. 2022 Mar 18; 7(1):19. Birnbaum F, Eguchi A, Pardon G, Chang ACY, Blau HM. PMID: 35304486; PMCID: PMC8933505.
      View in: PubMed   Mentions: 2  
    3. Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes. Stem Cell Reports. 2021 09 14; 16(9):2169-2181. Chang ACY, Pardon G, Chang ACH, Wu H, Ong SG, Eguchi A, Ancel S, Holbrook C, Ramunas J, Ribeiro AJS, LaGory EL, Wang H, Koleckar K, Giaccia A, Mack DL, Childers MK, Denning C, Day JW, Wu JC, Pruitt BL, Blau HM. PMID: 34019816; PMCID: PMC8452491.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    4. Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome. PLoS One. 2020; 15(12):e0243905. Finn PB, Bhimsaria D, Ali A, Eguchi A, Ansari AZ, Dervan PB. PMID: 33351840; PMCID: PMC7755219.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Reprogramming cell fate with artificial transcription factors. FEBS Lett. 2018 03; 592(6):888-900. Heiderscheit EA, Eguchi A, Spurgat MC, Ansari AZ. PMID: 29389011; PMCID: PMC5869137.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    6. Synthetic transcription elongation factors license transcription across repressive chromatin. Science. 2017 12 22; 358(6370):1617-1622. Erwin GS, Grieshop MP, Ali A, Qi J, Lawlor M, Kumar D, Ahmad I, McNally A, Teider N, Worringer K, Sivasankaran R, Syed DN, Eguchi A, Ashraf M, Jeffery J, Xu M, Park PMC, Mukhtar H, Srivastava AK, Faruq M, Bradner JE, Ansari AZ. PMID: 29192133; PMCID: PMC6037176.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    7. Reprogramming cell fate with a genome-scale library of artificial transcription factors. Proc Natl Acad Sci U S A. 2016 12 20; 113(51):E8257-E8266. Eguchi A, Wleklinski MJ, Spurgat MC, Heiderscheit EA, Kropornicka AS, Vu CK, Bhimsaria D, Swanson SA, Stewart R, Ramanathan P, Kamp TJ, Slukvin I, Thomson JA, Dutton JR, Ansari AZ. PMID: 27930301; PMCID: PMC5187731.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    8. Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin). J Vis Exp. 2016 Jan 20; (107):e53510. Erwin GS, Grieshop MP, Bhimsaria D, Eguchi A, Rodríguez-Martínez JA, Ansari AZ. PMID: 26863565; PMCID: PMC4781686.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers. Biochem J. 2014 Sep 15; 462(3):397-413. Eguchi A, Lee GO, Wan F, Erwin GS, Ansari AZ. PMID: 25145439; PMCID: PMC4205157.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    10. Mapping polyamide-DNA interactions in human cells reveals a new design strategy for effective targeting of genomic sites. Angew Chem Int Ed Engl. 2014 Sep 15; 53(38):10124-8. Erwin GS, Bhimsaria D, Eguchi A, Ansari AZ. PMID: 25066383; PMCID: PMC4160732.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    11. Differential sensitivity of oligodendrocytes and motor neurons to reactive nitrogen species: implications for multiple sclerosis. J Neurochem. 2009 Apr; 109(1):93-104. Bishop A, Hobbs KG, Eguchi A, Jeffrey S, Smallwood L, Pennie C, Anderson J, Estévez AG. PMID: 19226373; PMCID: PMC2756289.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    12. Mitigation of peroxynitrite-mediated nitric oxide (NO) toxicity as a mechanism of induced adaptive NO resistance in the CNS. J Neurochem. 2009 Apr; 109(1):74-84. Bishop A, Gooch R, Eguchi A, Jeffrey S, Smallwood L, Anderson J, Estevez AG. PMID: 19183270; PMCID: PMC2692600.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
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