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Unrecognised actionability for breast cancer risk variants identified in a national-level review of Australian familial cancer centres. Eur J Hum Genet. 2024 Dec; 32(12):1632-1639.
Fortuno C, Cops EJ, Davidson AL, Hadler J, Innella G, McKenzie ME, Parsons M, Campbell AM, Dubowsky A, Fargas V, Field MJ, Mar Fan HG, Nichols CB, Poplawski NK, Warwick L, Williams R, Beshay V, Edwards C, Johns A, McPhillips M, Kumar VS, Scott R, Williams M, Scott H, James PA, Spurdle AB. PMID: 39402389; PMCID: PMC11607406.
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PubMed Mentions: Fields:
Translation:
Humans
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Challenges and approaches to calibrating patient phenotype as evidence for cancer gene variant classification under ACMG/AMP guidelines. Hum Mol Genet. 2024 04 08; 33(8):724-732.
Fortuno C, Michailidou K, Parsons M, Dolinsky JS, Pesaran T, Yussuf A, Mester JL, Hruska KS, Hiraki S, O'Connor R, Chan RC, Kim S, Tavtigian SV, Goldgar D, James PA, Spurdle AB. PMID: 38271184; PMCID: PMC11000651.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Generation and application of endogenously floxed alleles for cell-specific knockout in zebrafish. Dev Cell. 2023 11 20; 58(22):2614-2626.e7.
Shin M, Yin HM, Shih YH, Nozaki T, Portman D, Toles B, Kolb A, Luk K, Isogai S, Ishida K, Hanasaka T, Parsons MJ, Wolfe SA, Burns CE, Burns CG, Lawson ND. PMID: 37633272; PMCID: PMC10840978.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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An inducible model of chronic hyperglycemia. Dis Model Mech. 2023 08 01; 16(8).
Tucker TR, Knitter CA, Khoury DM, Eshghi S, Tran S, Sharrock AV, Wiles TJ, Ackerley DF, Mumm JS, Parsons MJ. PMID: 37401381; PMCID: PMC10417516.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Brain metastases: A Society for Neuro-Oncology (SNO) consensus review on current management and future directions. Neuro Oncol. 2022 10 03; 24(10):1613-1646.
Aizer AA, Lamba N, Ahluwalia MS, Aldape K, Boire A, Brastianos PK, Brown PD, Camidge DR, Chiang VL, Davies MA, Hu LS, Huang RY, Kaufmann T, Kumthekar P, Lam K, Lee EQ, Lin NU, Mehta M, Parsons M, Reardon DA, Sheehan J, Soffietti R, Tawbi H, Weller M, Wen PY. PMID: 35762249; PMCID: PMC9527527.
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PubMed Mentions:
65 Fields:
Translation:
Humans
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Design of a randomized, placebo-controlled, phase 2 study evaluating the safety and efficacy of tanezumab for treatment of schwannomatosis-related pain. Contemp Clin Trials. 2022 10; 121:106900.
Da JLW, Merker VL, Jordan JT, Ly KI, Muzikansky A, Parsons M, Wolters PL, Xu L, Styren S, Brown MT, Plotkin SR. PMID: 36038003.
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PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Elevated glycolysis imparts functional ability to CD8+ T cells in HIV infection. Life Sci Alliance. 2021 11; 4(11).
Rahman AN, Liu J, Mujib S, Kidane S, Ali A, Szep S, Han C, Bonner P, Parsons M, Benko E, Kovacs C, Yue FY, Ostrowski M. PMID: 34548381; PMCID: PMC8473722.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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SOX9 modulates cancer biomarker and cilia genes in pancreatic cancer. Hum Mol Genet. 2021 04 30; 30(6):485-499.
Edelman HE, McClymont SA, Tucker TR, Pineda S, Beer RL, McCallion AS, Parsons MJ. PMID: 33693707; PMCID: PMC8101357.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Attenuating the Epidermal Growth Factor Receptor-Extracellular Signal-Regulated Kinase-Sex-Determining Region Y-Box 9 Axis Promotes Liver Progenitor Cell-Mediated Liver Regeneration in Zebrafish. Hepatology. 2021 04; 73(4):1494-1508.
So J, Kim M, Lee SH, Ko S, Lee DA, Park H, Azuma M, Parsons MJ, Prober D, Shin D. PMID: 32602149; PMCID: PMC7769917.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Classification of variants of uncertain significance in BRCA1 and BRCA2 using personal and family history of cancer from individuals in a large hereditary cancer multigene panel testing cohort. Genet Med. 2020 04; 22(4):701-708.
Li H, LaDuca H, Pesaran T, Chao EC, Dolinsky JS, Parsons M, Spurdle AB, Polley EC, Shimelis H, Hart SN, Hu C, Couch FJ, Goldgar DE. PMID: 31853058; PMCID: PMC7118020.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Endoderm Jagged induces liver and pancreas duct lineage in zebrafish. Nat Commun. 2017 10 03; 8(1):769.
Zhang D, Gates KP, Barske L, Wang G, Lancman JJ, Zeng XI, Groff M, Wang K, Parsons MJ, Crump JG, Dong PDS. PMID: 28974684; PMCID: PMC5626745.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Sox9b is a mediator of retinoic acid signaling restricting endocrine progenitor differentiation. Dev Biol. 2016 10 01; 418(1):28-39.
Huang W, Beer RL, Delaspre F, Wang G, Edelman HE, Park H, Azuma M, Parsons MJ. PMID: 27565026; PMCID: PMC5031550.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Gfap-positive radial glial cells are an essential progenitor population for later-born neurons and glia in the zebrafish spinal cord. Glia. 2016 07; 64(7):1170-89.
Johnson K, Barragan J, Bashiruddin S, Smith CJ, Tyrrell C, Parsons MJ, Doris R, Kucenas S, Downes GB, Velez CM, Schneider C, Sakai C, Pathak N, Anderson K, Stein R, Devoto SH, Mumm JS, Barresi MJ. PMID: 27100776; PMCID: PMC4918407.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Naturally occurring BRCA2 alternative mRNA splicing events in clinically relevant samples. J Med Genet. 2016 08; 53(8):548-58.
Fackenthal JD, Yoshimatsu T, Zhang B, de Garibay GR, Colombo M, De Vecchi G, Ayoub SC, Lal K, Olopade OI, Vega A, Santamariña M, Blanco A, Wappenschmidt B, Becker A, Houdayer C, Walker LC, López-Perolio I, Thomassen M, Parsons M, Whiley P, Blok MJ, Brandão RD, Tserpelis D, Baralle D, Montalban G, Gutiérrez-Enríquez S, Díez O, Lazaro C, kConFaB Investigators, Spurdle AB, Radice P, de la Hoya M. PMID: 27060066.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Centroacinar cells: At the center of pancreas regeneration. Dev Biol. 2016 May 01; 413(1):8-15.
Beer RL, Parsons MJ, Rovira M. PMID: 26963675; PMCID: PMC4834238.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass. Elife. 2015 Jul 28; 4.
Wang G, Rajpurohit SK, Delaspre F, Walker SL, White DT, Ceasrine A, Kuruvilla R, Li RJ, Shim JS, Liu JO, Parsons MJ, Mumm JS. PMID: 26218223; PMCID: PMC4534842.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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Centroacinar Cells Are Progenitors That Contribute to Endocrine Pancreas Regeneration. Diabetes. 2015 Oct; 64(10):3499-509.
Delaspre F, Beer RL, Rovira M, Huang W, Wang G, Gee S, Vitery Mdel C, Wheelan SJ, Parsons MJ. PMID: 26153247; PMCID: PMC4587647.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Fate mapping of ptf1a-expressing cells during pancreatic organogenesis and regeneration in zebrafish. Dev Dyn. 2015 Jun; 244(6):724-35.
Wang YJ, Park JT, Parsons MJ, Leach SD. PMID: 25773748; PMCID: PMC4838417.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Carbamate nerve agent prophylatics exhibit distinct toxicological effects in the zebrafish embryo model. Neurotoxicol Teratol. 2015 Jul-Aug; 50:1-10.
Fischer A, Wolman M, Granato M, Parsons M, McCallion AS, Proescher J, English E. PMID: 25968237.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Retinoic acid plays an evolutionarily conserved and biphasic role in pancreas development. Dev Biol. 2014 Oct 01; 394(1):83-93.
Huang W, Wang G, Delaspre F, Vitery Mdel C, Beer RL, Parsons MJ. PMID: 25127993; PMCID: PMC4623430.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey. Oncogene. 2015 May 21; 34(21):2801-6.
Park JT, Johnson N, Liu S, Levesque M, Wang YJ, Ho H, Huso D, Maitra A, Parsons MJ, Prescott JD, Leach SD. PMID: 25065594; PMCID: PMC4836617.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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Distinct Notch signaling outputs pattern the developing arterial system. Development. 2014 Apr; 141(7):1544-52.
Quillien A, Moore JC, Shin M, Siekmann AF, Smith T, Pan L, Moens CB, Parsons MJ, Lawson ND. PMID: 24598161; PMCID: PMC4074308.
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PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Aldh1-expressing endocrine progenitor cells regulate secondary islet formation in larval zebrafish pancreas. PLoS One. 2013; 8(9):e74350.
Matsuda H, Parsons MJ, Leach SD. PMID: 24147152; PMCID: PMC3798260.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Adoption of the Q transcriptional regulatory system for zebrafish transgenesis. Methods. 2014 Apr 01; 66(3):433-40.
Subedi A, Macurak M, Gee ST, Monge E, Goll MG, Potter CJ, Parsons MJ, Halpern ME. PMID: 23792917; PMCID: PMC3883888.
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PubMed Mentions:
35 Fields:
Translation:
Animals
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Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development. Development. 2012 Sep; 139(17):3232-41.
Provost E, Wehner KA, Zhong X, Ashar F, Nguyen E, Green R, Parsons MJ, Leach SD. PMID: 22872088; PMCID: PMC3413166.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
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Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration. Dev Biol. 2012 Jun 15; 366(2):268-78.
Manfroid I, Ghaye A, Naye F, Detry N, Palm S, Pan L, Ma TP, Huang W, Rovira M, Martial JA, Parsons MJ, Moens CB, Voz ML, Peers B. PMID: 22537488; PMCID: PMC3364407.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish. PLoS One. 2012; 7(1):e29916.
Walker SL, Ariga J, Mathias JR, Coothankandaswamy V, Xie X, Distel M, Köster RW, Parsons MJ, Bhalla KN, Saxena MT, Mumm JS. PMID: 22238673; PMCID: PMC3251595.
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PubMed Mentions:
54 Fields:
Translation:
Animals
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Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):19264-9.
Rovira M, Huang W, Yusuff S, Shim JS, Ferrante AA, Liu JO, Parsons MJ. PMID: 22084084; PMCID: PMC3228434.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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Genetic inducible fate mapping in larval zebrafish reveals origins of adult insulin-producing β-cells. Development. 2011 Feb; 138(4):609-17.
Wang Y, Rovira M, Yusuff S, Parsons MJ. PMID: 21208992; PMCID: PMC3026409.
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PubMed Mentions:
64 Fields:
Translation:
AnimalsCells
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In vivo development of outer retinal synapses in the absence of glial contact. J Neurosci. 2010 Sep 08; 30(36):11951-61.
Williams PR, Suzuki SC, Yoshimatsu T, Lawrence OT, Waldron SJ, Parsons MJ, Nonet ML, Wong RO. PMID: 20826659; PMCID: PMC2946228.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Proneural gene-linked neurogenesis in zebrafish cerebellum. Dev Biol. 2010 Jul 01; 343(1-2):1-17.
Kani S, Bae YK, Shimizu T, Tanabe K, Satou C, Parsons MJ, Scott E, Higashijima S, Hibi M. PMID: 20388506.
View in:
PubMed Mentions:
81 Fields:
Translation:
AnimalsCells
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A novel model of retinal ablation demonstrates that the extent of rod cell death regulates the origin of the regenerated zebrafish rod photoreceptors. J Comp Neurol. 2010 Mar 15; 518(6):800-14.
Montgomery JE, Parsons MJ, Hyde DR. PMID: 20058308; PMCID: PMC3656417.
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PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
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Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas. Mech Dev. 2009 Oct; 126(10):898-912.
Parsons MJ, Pisharath H, Yusuff S, Moore JC, Siekmann AF, Lawson N, Leach SD. PMID: 19595765; PMCID: PMC3640481.
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PubMed Mentions:
230 Fields:
Translation:
Animals
-
Regeneration of the pancreas in adult zebrafish. Diabetes. 2009 Aug; 58(8):1844-51.
Moss JB, Koustubhan P, Greenman M, Parsons MJ, Walter I, Moss LG. PMID: 19491207; PMCID: PMC2712797.
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PubMed Mentions:
75 Fields:
Translation:
HumansAnimalsCells
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Nitroreductase-mediated cell ablation in transgenic zebrafish embryos. Methods Mol Biol. 2009; 546:133-43.
Pisharath H, Parsons MJ. PMID: 19378102.
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PubMed Mentions:
50 Fields:
Translation:
Animals
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Gal4/UAS transgenic tools and their application to zebrafish. Zebrafish. 2008; 5(2):97-110.
Halpern ME, Rhee J, Goll MG, Akitake CM, Parsons M, Leach SD. PMID: 18554173; PMCID: PMC6469517.
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PubMed Mentions:
113 Fields:
Translation:
Animals
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Transactivation from Gal4-VP16 transgenic insertions for tissue-specific cell labeling and ablation in zebrafish. Dev Biol. 2007 Apr 15; 304(2):811-24.
Davison JM, Akitake CM, Goll MG, Rhee JM, Gosse N, Baier H, Halpern ME, Leach SD, Parsons MJ. PMID: 17335798; PMCID: PMC3470427.
View in:
PubMed Mentions:
225 Fields:
Translation:
AnimalsCells
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Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase. Mech Dev. 2007 Mar; 124(3):218-29.
Pisharath H, Rhee JM, Swanson MA, Leach SD, Parsons MJ. PMID: 17223324; PMCID: PMC2583263.
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PubMed Mentions:
214 Fields:
Translation:
AnimalsCells
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Essential and overlapping roles for laminin alpha chains in notochord and blood vessel formation. Dev Biol. 2006 Jan 01; 289(1):64-76.
Pollard SM, Parsons MJ, Kamei M, Kettleborough RN, Thomas KA, Pham VN, Bae MK, Scott A, Weinstein BM, Stemple DL. PMID: 16321372.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Differential requirements for COPI transport during vertebrate early development. Dev Cell. 2004 Oct; 7(4):547-58.
Coutinho P, Parsons MJ, Thomas KA, Hirst EM, Saúde L, Campos I, Williams PH, Stemple DL. PMID: 15469843.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Lefty antagonism of Squint is essential for normal gastrulation. Curr Biol. 2002 Dec 23; 12(24):2129-35.
Feldman B, Concha ML, Saúde L, Parsons MJ, Adams RJ, Wilson SW, Stemple DL. PMID: 12498688.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos. Development. 2002 Jul; 129(14):3505-12.
Parsons MJ, Campos I, Hirst EM, Stemple DL. PMID: 12091319.
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PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Zebrafish mutants identify an essential role for laminins in notochord formation. Development. 2002 Jul; 129(13):3137-46.
Parsons MJ, Pollard SM, Saúde L, Feldman B, Coutinho P, Hirst EM, Stemple DL. PMID: 12070089.
View in:
PubMed Mentions:
104 Fields:
Translation:
Animals