David Sultzer

Title(s)Professor, Psychiatry
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
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    1. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. medRxiv. 2023 Jul 08. Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Wang LS, Farrer LA, Haines JL, et al. PMID: 37461624; PMCID: PMC10350126.
      View in: PubMed   Mentions:
    2. Centralizing prescreening data collection to inform data-driven approaches to clinical trial recruitment. Alzheimers Res Ther. 2023 05 02; 15(1):88. Kirn DR, Grill JD, Aisen P, Ernstrom K, Gale S, Heidebrink J, Jicha G, Jimenez-Maggiora G, Johnson L, Peskind E, McCann K, Shaffer E, Sultzer D, Wang S, Sperling R, Raman R. PMID: 37131229; PMCID: PMC10152012.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Visit-To-Visit Blood Pressure Variability and Subthreshold Depressive Symptoms in Older Adults. Am J Geriatr Psychiatry. 2022 10; 30(10):1110-1119. Sible IJ, Jang JY, Sultzer DL, Nation DA, Alzheimer's Disease Neuroimaging Initiative. PMID: 35487831; PMCID: PMC10064018.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    4. Cholinergic receptor binding in unimpaired older adults, mild cognitive impairment, and Alzheimer's disease dementia. Alzheimers Res Ther. 2022 02 07; 14(1):25. Sultzer DL, Lim AC, Gordon HL, Yarns BC, Melrose RJ. PMID: 35130968; PMCID: PMC8819935.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    5. Pimavanserin and dementia-related psychosis. Lancet Neurol. 2022 02; 21(2):114-115. Tariot PN, Ballard C, Devanand DP, Cummings JL, Sultzer DL. PMID: 35065031.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Anxiety and Depressive Symptoms and Cortical Amyloid-β Burden in Cognitively Unimpaired Older Adults. J Prev Alzheimers Dis. 2022; 9(2):286-296. Lewis CK, Bernstein OM, Grill JD, Gillen DL, Sultzer DL. PMID: 35543002.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Trial of Pimavanserin in Dementia-Related Psychosis. N Engl J Med. 2021 07 22; 385(4):309-319. Tariot PN, Cummings JL, Soto-Martin ME, Ballard C, Erten-Lyons D, Sultzer DL, Devanand DP, Weintraub D, McEvoy B, Youakim JM, Stankovic S, Foff EP. PMID: 34289275.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    8. Apathy as a Treatment Target in Alzheimer's Disease: Implications for Clinical Trials. Am J Geriatr Psychiatry. 2022 02; 30(2):119-147. Mortby ME, Adler L, Agüera-Ortiz L, Bateman DR, Brodaty H, Cantillon M, Geda YE, Ismail Z, Lanctôt KL, Marshall GA, Padala PR, Politis A, Rosenberg PB, Siarkos K, Sultzer DL, Theleritis C, ISTAART NPS PIA. PMID: 34315645.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    9. Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment. JAMA Neurol. 2020 12 01; 77(12):1504-1513. Grill JD, Raman R, Ernstrom K, Sultzer DL, Burns JM, Donohue MC, Johnson KA, Aisen PS, Sperling RA, Karlawish J, A4 Study Team. PMID: 32777010; PMCID: PMC7418046.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCTClinical Trials
    10. Emotional Awareness and Expression Therapy Achieves Greater Pain Reduction than Cognitive Behavioral Therapy in Older Adults with Chronic Musculoskeletal Pain: A Preliminary Randomized Comparison Trial. Pain Med. 2020 11 01; 21(11):2811-2822. Yarns BC, Lumley MA, Cassidy JT, Steers WN, Osato S, Schubiner H, Sultzer DL. PMID: 32451528.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    11. Prefrontal working memory activity predicts episodic memory performance: A neuroimaging study. Behav Brain Res. 2020 02 03; 379:112307. Melrose RJ, Zahniser E, Wilkins SS, Veliz J, Hasratian AS, Sultzer DL, Jimenez AM. PMID: 31678217.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    12. Mild Behavioral Impairment: A New Domain of Late-Life Psychiatric Symptoms. Am J Geriatr Psychiatry. 2019 08; 27(8):835-837. Sultzer DL. PMID: 30929964.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Alterations to task positive and task negative networks during executive functioning in Mild Cognitive Impairment. Neuroimage Clin. 2018; 19:970-981. Melrose RJ, Jimenez AM, Riskin-Jones H, Weissberger G, Veliz J, Hasratian AS, Wilkins S, Sultzer DL. PMID: 30003034; PMCID: PMC6039844.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    14. Sertraline for the Treatment of Depression in Vascular Cognitive Impairment. Am J Geriatr Psychiatry. 2018 08; 26(8):908-909. Weissberger GH, Yarns BC, Chen ST, Narvaez T, Bussel N, Sultzer DL. PMID: 29779907.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    15. The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable. Alzheimers Dement. 2018 04; 14(4):563-575. Knopman DS, Haeberlein SB, Carrillo MC, Hendrix JA, Kerchner G, Margolin R, Maruff P, Miller DS, Tong G, Tome MB, Murray ME, Nelson PT, Sano M, Mattsson N, Sultzer DL, Montine TJ, Jack CR, Kolb H, Petersen RC, Vemuri P, Canniere MZ, Schneider JA, Resnick SM, Romano G, van Harten AC, Wolk DA, Bain LJ, Siemers E. PMID: 29653607; PMCID: PMC6747694.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    16. Cognitive ageing and Alzheimer's disease: the cholinergic system redux. Brain. 2018 03 01; 141(3):626-628. Sultzer DL. PMID: 30753416.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    17. Why Apathy in Alzheimer's Matters. Am J Psychiatry. 2018 02 01; 175(2):99-100. Sultzer DL. PMID: 29385833.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. Cerebral metabolic correlates of attention networks in Alzheimer's Disease: A study of the Stroop. Neuropsychologia. 2017 Nov; 106:383-389. Melrose RJ, Young S, Weissberger GH, Natta L, Harwood D, Mandelkern M, Sultzer DL. PMID: 29055679; PMCID: PMC5708591.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Neuromodulation for Treatment-Refractory PTSD. Fed Pract. 2017 Mar; 34(Suppl 2):20S-33S. Langevin JP, Koek RJ, Schwartz HN, Chen JWY, Sultzer DL, Mandelkern MA, Kulick AD, Krahl SE. PMID: 30766304; PMCID: PMC6375501.
      View in: PubMed   Mentions: 1  
    20. 18F-Fluorodeoxyglucose Positron Emission Tomography Cortical Metabolic Activity Associated with Distinct Agitation Behaviors in Alzheimer Disease. Am J Geriatr Psychiatry. 2017 Jun; 25(6):569-579. Weissberger GH, Melrose RJ, Narvaez TA, Harwood D, Mandelkern MA, Sultzer DL. PMID: 28215899.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    21. Cholinergic Receptor Binding in Alzheimer Disease and Healthy Aging: Assessment In Vivo with Positron Emission Tomography Imaging. Am J Geriatr Psychiatry. 2017 Apr; 25(4):342-353. Sultzer DL, Melrose RJ, Riskin-Jones H, Narvaez TA, Veliz J, Ando TK, Juarez KO, Harwood DG, Brody AL, Mandelkern MA. PMID: 28162919.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    22. The Mild Behavioral Impairment Checklist (MBI-C): A Rating Scale for Neuropsychiatric Symptoms in Pre-Dementia Populations. J Alzheimers Dis. 2017; 56(3):929-938. Ismail Z, Agüera-Ortiz L, Brodaty H, Cieslak A, Cummings J, Fischer CE, Gauthier S, Geda YE, Herrmann N, Kanji J, Lanctôt KL, Miller DS, Mortby ME, Onyike CU, Rosenberg PB, Smith EE, Smith GS, Sultzer DL, Lyketsos C, NPS Professional Interest Area of the International Society of to Advance Alzheimer’s Research and T. PMID: 28059789; PMCID: PMC5652315.
      View in: PubMed   Mentions: 128     Fields:    Translation:Humans
    23. Cortical Metabolic and Cognitive Correlates of Disorientation in Alzheimer's Disease. J Alzheimers Dis. 2017; 60(2):707-719. Weissberger GH, Melrose RJ, Fanale CM, Veliz JV, Sultzer DL. PMID: 28869474.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. The functional neuroanatomy of verbal memory in Alzheimer's disease: [18F]-Fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) correlates of recency and recognition memory. J Clin Exp Neuropsychol. 2017 Sep; 39(7):682-693. Staffaroni AM, Melrose RJ, Leskin LP, Riskin-Jones H, Harwood D, Mandelkern M, Sultzer DL. PMID: 27876444.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    25. Prediction of Relapse After Discontinuation of Antipsychotic Treatment in Alzheimer's Disease: The Role of Hallucinations. Am J Psychiatry. 2017 04 01; 174(4):362-369. Patel AN, Lee S, Andrews HF, Pelton GH, Schultz SK, Sultzer DL, Mintzer J, de la Pena D, Gupta S, Colon S, Schimming C, Levin B, Devanand DP. PMID: 27855483; PMCID: PMC5378647.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    26. Older Brains are Different: Brain-Behavior Studies and Their Clinical Utility. Am J Geriatr Psychiatry. 2017 01; 25(1):11-12. Sultzer DL, Marder SR. PMID: 28231870.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Deep Brain Stimulation of the Basolateral Amygdala: Targeting Technique and Electrodiagnostic Findings. Brain Sci. 2016 Aug 10; 6(3). Langevin JP, Chen JW, Koek RJ, Sultzer DL, Mandelkern MA, Schwartz HN, Krahl SE. PMID: 27517963; PMCID: PMC5039457.
      View in: PubMed   Mentions: 18  
    28. Apathy associated with neurocognitive disorders: Recent progress and future directions. Alzheimers Dement. 2017 01; 13(1):84-100. Lanctôt KL, Agüera-Ortiz L, Brodaty H, Francis PT, Geda YE, Ismail Z, Marshall GA, Mortby ME, Onyike CU, Padala PR, Politis AM, Rosenberg PB, Siegel E, Sultzer DL, Abraham EH. PMID: 27362291.
      View in: PubMed   Mentions: 70     Fields:    Translation:Humans
    29. Deep Brain Stimulation of the Basolateral Amygdala for Treatment-Refractory Posttraumatic Stress Disorder. Biol Psychiatry. 2016 05 15; 79(10):e82-e84. Langevin JP, Koek RJ, Schwartz HN, Chen JWY, Sultzer DL, Mandelkern MA, Kulick AD, Krahl SE. PMID: 26475671.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    30. Neuropsychiatric symptoms as early manifestations of emergent dementia: Provisional diagnostic criteria for mild behavioral impairment. Alzheimers Dement. 2016 Feb; 12(2):195-202. Ismail Z, Smith EE, Geda Y, Sultzer D, Brodaty H, Smith G, Agüera-Ortiz L, Sweet R, Miller D, Lyketsos CG, ISTAART Neuropsychiatric Symptoms Professional Interest Area. PMID: 26096665; PMCID: PMC4684483.
      View in: PubMed   Mentions: 226     Fields:    Translation:Humans
    31. Brain structure and function related to depression in Alzheimer's disease: contributions from neuroimaging research. J Alzheimers Dis. 2015; 45(3):689-703. Brommelhoff JA, Sultzer DL. PMID: 25633682.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    32. Deep brain stimulation of the basolateral amygdala for treatment-refractory combat post-traumatic stress disorder (PTSD): study protocol for a pilot randomized controlled trial with blinded, staggered onset of stimulation. Trials. 2014 Sep 10; 15:356. Koek RJ, Langevin JP, Krahl SE, Kosoyan HJ, Schwartz HN, Chen JW, Melrose R, Mandelkern MJ, Sultzer D. PMID: 25208824; PMCID: PMC4168122.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCTClinical Trials
    33. Differences in anxiety among patients with early- versus late-onset Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 2014; 26(1):73-80. Kaiser NC, Liang LJ, Melrose RJ, Wilkins SS, Sultzer DL, Mendez MF. PMID: 24515678.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    34. Cerebrospinal fluid biomarkers in clinical subtypes of early-onset Alzheimer's disease. Dement Geriatr Cogn Disord. 2014; 37(5-6):307-14. Teng E, Yamasaki TR, Tran M, Hsiao JJ, Sultzer DL, Mendez MF. PMID: 24401901; PMCID: PMC4057962.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    35. Neurobiology of delusions, memory, and insight in Alzheimer disease. Am J Geriatr Psychiatry. 2014 Nov; 22(11):1346-55. Sultzer DL, Leskin LP, Melrose RJ, Harwood DG, Narvaez TA, Ando TK, Mandelkern MA. PMID: 24021220; PMCID: PMC4254898.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    36. Insight in Alzheimer's disease and its relation to psychiatric and behavioral disturbances. Int J Geriatr Psychiatry. 2014 Jan; 29(1):77-84. Horning SM, Melrose R, Sultzer D. PMID: 23671016; PMCID: PMC3796120.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    37. Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future. Alzheimers Dement. 2013 Sep; 9(5):602-8. Geda YE, Schneider LS, Gitlin LN, Miller DS, Smith GS, Bell J, Evans J, Lee M, Porsteinsson A, Lanctôt KL, Rosenberg PB, Sultzer DL, Francis PT, Brodaty H, Padala PP, Onyike CU, Ortiz LA, Ancoli-Israel S, Bliwise DL, Martin JL, Vitiello MV, Yaffe K, Zee PC, Herrmann N, Sweet RA, Ballard C, Khin NA, Alfaro C, Murray PS, Schultz S, Lyketsos CG, Neuropsychiatric Syndromes Professional Interest Area of ISTAART. PMID: 23562430; PMCID: PMC3766403.
      View in: PubMed   Mentions: 140     Fields:    Translation:Humans
    38. Association between cerebral metabolism and Rey-Osterrieth Complex Figure Test performance in Alzheimer's disease. J Clin Exp Neuropsychol. 2013; 35(3):246-58. Melrose RJ, Harwood D, Khoo T, Mandelkern M, Sultzer DL. PMID: 23387510; PMCID: PMC3727972.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    39. Discontinuation of risperidone in Alzheimer's disease. N Engl J Med. 2013 01 10; 368(2):187-8. Devanand DP, Schultz SK, Sultzer DL. PMID: 23301737.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    40. Relapse risk after discontinuation of risperidone in Alzheimer's disease. N Engl J Med. 2012 Oct 18; 367(16):1497-507. Devanand DP, Mintzer J, Schultz SK, Andrews HF, Sultzer DL, de la Pena D, Gupta S, Colon S, Schimming C, Pelton GH, Levin B. PMID: 23075176; PMCID: PMC3490406.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    41. Neuropsychological and neuroimaging markers in early versus late-onset Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2012 Nov; 27(7):520-9. Kaiser NC, Melrose RJ, Liu C, Sultzer DL, Jimenez E, Su M, Monserratt L, Mendez MF. PMID: 22990206; PMCID: PMC4112191.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    42. The antipsychotic discontinuation in Alzheimer disease trial: clinical rationale and study design. Am J Geriatr Psychiatry. 2012 Apr; 20(4):362-73. Devanand DP, Mintzer J, Schultz S, Sultzer D, de la Pena D, Gupta S, Colon S, Schimming C, Pelton GH, Andrews H, Levin B. PMID: 21407047; PMCID: PMC3146556.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis. JAMA. 2011 Sep 28; 306(12):1359-69. Maher AR, Maglione M, Bagley S, Suttorp M, Hu JH, Ewing B, Wang Z, Timmer M, Sultzer D, Shekelle PG. PMID: 21954480.
      View in: PubMed   Mentions: 161     Fields:    Translation:Humans
    44. Effect of second-generation antipsychotics on caregiver burden in Alzheimer's disease. J Clin Psychiatry. 2012 Jan; 73(1):121-8. Mohamed S, Rosenheck R, Lyketsos CG, Kaczynski R, Sultzer DL, Schneider LS. PMID: 21939611; PMCID: PMC4040971.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    45. Cerebral metabolism, cognition, and functional abilities in Alzheimer disease. J Geriatr Psychiatry Neurol. 2011 Sep; 24(3):127-34. Melrose RJ, Ettenhofer ML, Harwood D, Achamallah N, Campa O, Mandelkern M, Sultzer DL. PMID: 21856969.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    46. Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD. Am J Psychiatry. 2011 Aug; 168(8):831-9. Vigen CL, Mack WJ, Keefe RS, Sano M, Sultzer DL, Stroup TS, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, Tariot PN, Zheng L, Schneider LS. PMID: 21572163; PMCID: PMC3310182.
      View in: PubMed   Mentions: 85     Fields:    Translation:Humans
    47. Solanezumab for Alzheimer's disease. Expert Opin Biol Ther. 2011 Jun; 11(6):787-98. Samadi H, Sultzer D. PMID: 21504387.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    48. The relationship between cognitive impairment and diabetes self-management in a population-based community sample of older adults with Type 2 diabetes. J Behav Med. 2012 Apr; 35(2):190-9. Feil DG, Zhu CW, Sultzer DL. PMID: 21503710.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    49. Executive deficits and regional brain metabolism in Alzheimer's disease. Int J Geriatr Psychiatry. 2010 Nov; 25(11):1150-8. Woo BK, Harwood DG, Melrose RJ, Mandelkern MA, Campa OM, Walston A, Sultzer DL. PMID: 20069587.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    50. Effect of memantine treatment on regional cortical metabolism in Alzheimer's disease. Am J Geriatr Psychiatry. 2010 Jul; 18(7):606-14. Sultzer DL, Melrose RJ, Harwood DG, Campa O, Mandelkern MA. PMID: 20220580.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    51. A key step for quality care in psychiatric emergency settings. Gen Hosp Psychiatry. 2009 Nov-Dec; 31(6):503-4. Woo BK, Sultzer DL. PMID: 19892207.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    52. The neural correlates of naming and fluency deficits in Alzheimer's disease: an FDG-PET study. Int J Geriatr Psychiatry. 2009 Aug; 24(8):885-93. Melrose RJ, Campa OM, Harwood DG, Osato S, Mandelkern MA, Sultzer DL. PMID: 19296551; PMCID: PMC2743128.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    53. Metabolic changes associated with second-generation antipsychotic use in Alzheimer's disease patients: the CATIE-AD study. Am J Psychiatry. 2009 May; 166(5):583-90. Zheng L, Mack WJ, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, Stroup TS, Sultzer DL, Tariot PN, Vigen C, Schneider LS. PMID: 19369318; PMCID: PMC2891018.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    54. Clinical symptom responses to atypical antipsychotic medications in Alzheimer's disease: phase 1 outcomes from the CATIE-AD effectiveness trial. Am J Psychiatry. 2008 Jul; 165(7):844-54. Sultzer DL, Davis SM, Tariot PN, Dagerman KS, Lebowitz BD, Lyketsos CG, Rosenheck RA, Hsiao JK, Lieberman JA, Schneider LS, CATIE-AD Study Group. PMID: 18519523; PMCID: PMC2714365.
      View in: PubMed   Mentions: 105     Fields:    Translation:Humans
    55. Content-specific delusions from right caudate lacunar stroke: association with prefrontal hypometabolism. J Neuropsychiatry Clin Neurosci. 2008; 20(1):62-7. McMurtray AM, Sultzer DL, Monserratt L, Yeo T, Mendez MF. PMID: 18305285.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    56. Quality indicators for the care of dementia in vulnerable elders. J Am Geriatr Soc. 2007 Oct; 55 Suppl 2:S293-301. Feil DG, MacLean C, Sultzer D. PMID: 17910550.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    57. Positron emission tomography metabolic correlates of apathy in Alzheimer disease. Arch Neurol. 2007 Jul; 64(7):1015-20. Marshall GA, Monserratt L, Harwood D, Mandelkern M, Cummings JL, Sultzer DL. PMID: 17620493.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    58. Memory impairment among primary care veterans. Aging Ment Health. 2007 Jul; 11(4):444-50. Chodosh J, Sultzer DL, Lee ML, Hahn TJ, Reuben DB, Yano EM, Mittman BS, Rubenstein LZ. PMID: 17612808.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    59. Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease. N Engl J Med. 2006 Oct 12; 355(15):1525-38. Schneider LS, Tariot PN, Dagerman KS, Davis SM, Hsiao JK, Ismail MS, Lebowitz BD, Lyketsos CG, Ryan JM, Stroup TS, Sultzer DL, Weintraub D, Lieberman JA, CATIE-AD Study Group. PMID: 17035647.
      View in: PubMed   Mentions: 307     Fields:    Translation:Humans
    60. Anxiety and regional cortical glucose metabolism in patients with Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 2006; 18(4):521-8. Hashimoto H, Monserratt L, Nguyen P, Feil D, Harwood D, Mandelkern MA, Sultzer DL. PMID: 17135378.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    61. Frontal lobe hypometabolism and impaired insight in Alzheimer disease. Am J Geriatr Psychiatry. 2005 Nov; 13(11):934-41. Harwood DG, Sultzer DL, Feil D, Monserratt L, Freedman E, Mandelkern MA. PMID: 16286436.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    62. Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical "disconnection" in aging and Alzheimer's disease. Neurobiol Aging. 2004 Aug; 25(7):843-51. Bartzokis G, Sultzer D, Lu PH, Nuechterlein KH, Mintz J, Cummings JL. PMID: 15212838.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansCellsCTClinical Trials
    63. Psychosis and antipsychotic medications in Alzheimer's disease: clinical management and research perspectives. Dement Geriatr Cogn Disord. 2004; 17(1-2):78-90. Sultzer DL. PMID: 14566100.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    64. White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study. Arch Neurol. 2003 Mar; 60(3):393-8. Bartzokis G, Cummings JL, Sultzer D, Henderson VW, Nuechterlein KH, Mintz J. PMID: 12633151.
      View in: PubMed   Mentions: 168     Fields:    Translation:HumansCells
    65. Delusional thoughts and regional frontal/temporal cortex metabolism in Alzheimer's disease. Am J Psychiatry. 2003 Feb; 160(2):341-9. Sultzer DL, Brown CV, Mandelkern MA, Mahler ME, Mendez MF, Chen ST, Cummings JL. PMID: 12562582.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    66. Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE): Alzheimer's disease trial. Schizophr Bull. 2003; 29(1):57-72. Schneider LS, Ismail MS, Dagerman K, Davis S, Olin J, McManus D, Pfeiffer E, Ryan JM, Sultzer DL, Tariot PN. PMID: 12908661.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    67. Valproate-induced hyperammonemia as a cause of altered mental status. Am J Geriatr Psychiatry. 2002 Jul-Aug; 10(4):476-8. Feil D, Chuang K, Sultzer DL. PMID: 12095907.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    68. Subcortical hyperintensities in Alzheimer's disease: associated clinical and metabolic findings. J Neuropsychiatry Clin Neurosci. 2002; 14(3):262-9. Sultzer DL, Chen ST, Brown CV, Mahler ME, Cummings JL, Hinkin CH, Mandelkern MA. PMID: 12154149.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    69. "Life is not worth living": hopelessness in Alzheimer's disease. J Geriatr Psychiatry Neurol. 2002; 15(1):38-43. Harwood DG, Sultzer DL. PMID: 11936242.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    70. Does behavioral improvement with haloperidol or trazodone treatment depend on psychosis or mood symptoms in patients with dementia? J Am Geriatr Soc. 2001 Oct; 49(10):1294-300. Sultzer DL, Gray KF, Gunay I, Wheatley MV, Mahler ME. PMID: 11890487.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    71. Impaired insight in Alzheimer disease: association with cognitive deficits, psychiatric symptoms, and behavioral disturbances. Neuropsychiatry Neuropsychol Behav Neurol. 2000 Apr; 13(2):83-8. Harwood DG, Sultzer DL, Wheatley MV. PMID: 10780626.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    72. In vivo evaluation of brain iron in Alzheimer disease using magnetic resonance imaging. Arch Gen Psychiatry. 2000 Jan; 57(1):47-53. Bartzokis G, Sultzer D, Cummings J, Holt LE, Hance DB, Henderson VW, Mintz J. PMID: 10632232.
      View in: PubMed   Mentions: 74     Fields:    Translation:Humans
    73. Apolipoprotein E genotype and noncognitive symptoms in Alzheimer's disease. Biol Psychiatry. 1999 Feb 15; 45(4):422-5. Levy ML, Cummings JL, Fairbanks LA, Sultzer DL, Small GW. PMID: 10071711.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    74. Screening for dementia: comparison of three commonly used instruments. J Clin Exp Neuropsychol. 1999 Feb; 21(1):29-38. van Gorp WG, Marcotte TD, Sultzer D, Hinkin C, Mahler M, Cummings JL. PMID: 10420999.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    75. A structured trial of risperidone for the treatment of agitation in dementia. Am J Geriatr Psychiatry. 1998; 6(2):127-35. Lavretsky H, Sultzer D. PMID: 9581208.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    76. Executive dysfunction in Alzheimer's disease: association with neuropsychiatric symptoms and functional impairment. J Neuropsychiatry Clin Neurosci. 1998; 10(4):426-32. Chen ST, Sultzer DL, Hinkin CH, Mahler ME, Cummings JL. PMID: 9813788.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    77. A double-blind comparison of trazodone and haloperidol for treatment of agitation in patients with dementia. Am J Geriatr Psychiatry. 1997; 5(1):60-9. Sultzer DL, Gray KF, Gunay I, Berisford MA, Mahler ME. PMID: 9169246.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCTClinical Trials
    78. Cortical abnormalities associated with subcortical lesions in vascular dementia. Clinical and position emission tomographic findings. Arch Neurol. 1995 Aug; 52(8):773-80. Sultzer DL, Mahler ME, Cummings JL, Van Gorp WG, Hinkin CH, Brown C. PMID: 7639629.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    79. The Neurobehavioral Rating Scale: reliability in patients with dementia. J Psychiatr Res. 1995 May-Jun; 29(3):185-91. Sultzer DL, Berisford MA, Gunay I. PMID: 7473295.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    80. The relationship between psychiatric symptoms and regional cortical metabolism in Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 1995; 7(4):476-84. Sultzer DL, Mahler ME, Mandelkern MA, Cummings JL, Van Gorp WG, Hinkin CH, Berisford MA. PMID: 8555751.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    81. p(C) analysis facilitates dementia diagnosis. Med Decis Making. 1994 Oct-Dec; 14(4):393-402. Absher JR, Sultzer DL, Mahler ME, Fishman J. PMID: 7808214.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    82. In vivo MR evaluation of age-related increases in brain iron. AJNR Am J Neuroradiol. 1994 Jun; 15(6):1129-38. Bartzokis G, Mintz J, Sultzer D, Marx P, Herzberg JS, Phelan CK, Marder SR. PMID: 8073983; PMCID: PMC8333472.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    83. In vivo evaluation of brain iron in Alzheimer's disease and normal subjects using MRI. Biol Psychiatry. 1994 Apr 01; 35(7):480-7. Bartzokis G, Sultzer D, Mintz J, Holt LE, Marx P, Phelan CK, Marder SR. PMID: 8018799.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    84. A comparison of psychiatric symptoms in vascular dementia and Alzheimer's disease. Am J Psychiatry. 1993 Dec; 150(12):1806-12. Sultzer DL, Levin HS, Mahler ME, High WM, Cummings JL. PMID: 8238634.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    85. Assessment of cognitive, psychiatric, and behavioral disturbances in patients with dementia: the Neurobehavioral Rating Scale. J Am Geriatr Soc. 1992 Jun; 40(6):549-55. Sultzer DL, Levin HS, Mahler ME, High WM, Cummings JL. PMID: 1587970.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    86. Oral S-adenosylmethionine in depression: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry. 1990 May; 147(5):591-5. Kagan BL, Sultzer DL, Rosenlicht N, Gerner RH. PMID: 2183633.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCTClinical Trials
    87. Drug-induced mania--causative agents, clinical characteristics and management. A retrospective analysis of the literature. Med Toxicol Adverse Drug Exp. 1989 Mar-Apr; 4(2):127-43. Sultzer DL, Cummings JL. PMID: 2654543.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
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