David Sultzer

Title(s)Professor, Psychiatry
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
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    1. Cholinergic receptor binding in unimpaired older adults, mild cognitive impairment, and Alzheimer's disease dementia. Alzheimers Res Ther. 2022 02 07; 14(1):25. Sultzer DL, Lim AC, Gordon HL, Yarns BC, Melrose RJ. PMID: 35130968; PMCID: PMC8819935.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment. JAMA Neurol. 2020 12 01; 77(12):1504-1513. Grill JD, Raman R, Ernstrom K, Sultzer DL, Burns JM, Donohue MC, Johnson KA, Aisen PS, Sperling RA, Karlawish J, A4 Study Team. PMID: 32777010; PMCID: PMC7418046.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    3. Emotional Awareness and Expression Therapy Achieves Greater Pain Reduction than Cognitive Behavioral Therapy in Older Adults with Chronic Musculoskeletal Pain: A Preliminary Randomized Comparison Trial. Pain Med. 2020 11 01; 21(11):2811-2822. Yarns BC, Lumley MA, Cassidy JT, Steers WN, Osato S, Schubiner H, Sultzer DL. PMID: 32451528.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    4. Prefrontal working memory activity predicts episodic memory performance: A neuroimaging study. Behav Brain Res. 2020 02 03; 379:112307. Melrose RJ, Zahniser E, Wilkins SS, Veliz J, Hasratian AS, Sultzer DL, Jimenez AM. PMID: 31678217.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    5. Mild Behavioral Impairment: A New Domain of Late-Life Psychiatric Symptoms. Am J Geriatr Psychiatry. 2019 08; 27(8):835-837. Sultzer DL. PMID: 30929964.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Alterations to task positive and task negative networks during executive functioning in Mild Cognitive Impairment. Neuroimage Clin. 2018; 19:970-981. Melrose RJ, Jimenez AM, Riskin-Jones H, Weissberger G, Veliz J, Hasratian AS, Wilkins S, Sultzer DL. PMID: 30003034; PMCID: PMC6039844.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    7. Sertraline for the Treatment of Depression in Vascular Cognitive Impairment. Am J Geriatr Psychiatry. 2018 08; 26(8):908-909. Weissberger GH, Yarns BC, Chen ST, Narvaez T, Bussel N, Sultzer DL. PMID: 29779907.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    8. Cognitive ageing and Alzheimer's disease: the cholinergic system redux. Brain. 2018 03 01; 141(3):626-628. Sultzer DL. PMID: 30753416.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    9. Why Apathy in Alzheimer's Matters. Am J Psychiatry. 2018 02 01; 175(2):99-100. Sultzer DL. PMID: 29385833.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Cerebral metabolic correlates of attention networks in Alzheimer's Disease: A study of the Stroop. Neuropsychologia. 2017 Nov; 106:383-389. Melrose RJ, Young S, Weissberger GH, Natta L, Harwood D, Mandelkern M, Sultzer DL. PMID: 29055679; PMCID: PMC5708591.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Neuromodulation for Treatment-Refractory PTSD. Fed Pract. 2017 Mar; 34(Suppl 2):20S-33S. Langevin JP, Koek RJ, Schwartz HN, Chen JWY, Sultzer DL, Mandelkern MA, Kulick AD, Krahl SE. PMID: 30766304; PMCID: PMC6375501.
      View in: PubMed   Mentions:
    12. 18F-Fluorodeoxyglucose Positron Emission Tomography Cortical Metabolic Activity Associated with Distinct Agitation Behaviors in Alzheimer Disease. Am J Geriatr Psychiatry. 2017 Jun; 25(6):569-579. Weissberger GH, Melrose RJ, Narvaez TA, Harwood D, Mandelkern MA, Sultzer DL. PMID: 28215899.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    13. Cholinergic Receptor Binding in Alzheimer Disease and Healthy Aging: Assessment In Vivo with Positron Emission Tomography Imaging. Am J Geriatr Psychiatry. 2017 Apr; 25(4):342-353. Sultzer DL, Melrose RJ, Riskin-Jones H, Narvaez TA, Veliz J, Ando TK, Juarez KO, Harwood DG, Brody AL, Mandelkern MA. PMID: 28162919.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    14. Cortical Metabolic and Cognitive Correlates of Disorientation in Alzheimer's Disease. J Alzheimers Dis. 2017; 60(2):707-719. Weissberger GH, Melrose RJ, Fanale CM, Veliz JV, Sultzer DL. PMID: 28869474.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. The Mild Behavioral Impairment Checklist (MBI-C): A Rating Scale for Neuropsychiatric Symptoms in Pre-Dementia Populations. J Alzheimers Dis. 2017; 56(3):929-938. Ismail Z, Agüera-Ortiz L, Brodaty H, Cieslak A, Cummings J, Fischer CE, Gauthier S, Geda YE, Herrmann N, Kanji J, Lanctôt KL, Miller DS, Mortby ME, Onyike CU, Rosenberg PB, Smith EE, Smith GS, Sultzer DL, Lyketsos C, NPS Professional Interest Area of the International Society of to Advance Alzheimer’s Research and T. PMID: 28059789; PMCID: PMC5652315.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    16. The functional neuroanatomy of verbal memory in Alzheimer's disease: [18F]-Fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) correlates of recency and recognition memory. J Clin Exp Neuropsychol. 2017 Sep; 39(7):682-693. Staffaroni AM, Melrose RJ, Leskin LP, Riskin-Jones H, Harwood D, Mandelkern M, Sultzer DL. PMID: 27876444.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    17. Older Brains are Different: Brain-Behavior Studies and Their Clinical Utility. Am J Geriatr Psychiatry. 2017 01; 25(1):11-12. Sultzer DL, Marder SR. PMID: 28231870.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Deep Brain Stimulation of the Basolateral Amygdala: Targeting Technique and Electrodiagnostic Findings. Brain Sci. 2016 Aug 10; 6(3). Langevin JP, Chen JW, Koek RJ, Sultzer DL, Mandelkern MA, Schwartz HN, Krahl SE. PMID: 27517963; PMCID: PMC5039457.
      View in: PubMed   Mentions: 13  
    19. Deep Brain Stimulation of the Basolateral Amygdala for Treatment-Refractory Posttraumatic Stress Disorder. Biol Psychiatry. 2016 05 15; 79(10):e82-e84. Langevin JP, Koek RJ, Schwartz HN, Chen JWY, Sultzer DL, Mandelkern MA, Kulick AD, Krahl SE. PMID: 26475671.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    20. Neuropsychiatric symptoms as early manifestations of emergent dementia: Provisional diagnostic criteria for mild behavioral impairment. Alzheimers Dement. 2016 Feb; 12(2):195-202. Ismail Z, Smith EE, Geda Y, Sultzer D, Brodaty H, Smith G, Agüera-Ortiz L, Sweet R, Miller D, Lyketsos CG, ISTAART Neuropsychiatric Symptoms Professional Interest Area. PMID: 26096665; PMCID: PMC4684483.
      View in: PubMed   Mentions: 147     Fields:    Translation:Humans
    21. Brain structure and function related to depression in Alzheimer's disease: contributions from neuroimaging research. J Alzheimers Dis. 2015; 45(3):689-703. Brommelhoff JA, Sultzer DL. PMID: 25633682.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    22. Deep brain stimulation of the basolateral amygdala for treatment-refractory combat post-traumatic stress disorder (PTSD): study protocol for a pilot randomized controlled trial with blinded, staggered onset of stimulation. Trials. 2014 Sep 10; 15:356. Koek RJ, Langevin JP, Krahl SE, Kosoyan HJ, Schwartz HN, Chen JW, Melrose R, Mandelkern MJ, Sultzer D. PMID: 25208824; PMCID: PMC4168122.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCTClinical Trials
    23. Differences in anxiety among patients with early- versus late-onset Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 2014; 26(1):73-80. Kaiser NC, Liang LJ, Melrose RJ, Wilkins SS, Sultzer DL, Mendez MF. PMID: 24515678.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    24. Neurobiology of delusions, memory, and insight in Alzheimer disease. Am J Geriatr Psychiatry. 2014 Nov; 22(11):1346-55. Sultzer DL, Leskin LP, Melrose RJ, Harwood DG, Narvaez TA, Ando TK, Mandelkern MA. PMID: 24021220; PMCID: PMC4254898.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    25. Insight in Alzheimer's disease and its relation to psychiatric and behavioral disturbances. Int J Geriatr Psychiatry. 2014 Jan; 29(1):77-84. Horning SM, Melrose R, Sultzer D. PMID: 23671016; PMCID: PMC3796120.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    26. Association between cerebral metabolism and Rey-Osterrieth Complex Figure Test performance in Alzheimer's disease. J Clin Exp Neuropsychol. 2013; 35(3):246-58. Melrose RJ, Harwood D, Khoo T, Mandelkern M, Sultzer DL. PMID: 23387510; PMCID: PMC3727972.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    27. Neuropsychological and neuroimaging markers in early versus late-onset Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2012 Nov; 27(7):520-9. Kaiser NC, Melrose RJ, Liu C, Sultzer DL, Jimenez E, Su M, Monserratt L, Mendez MF. PMID: 22990206; PMCID: PMC4112191.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    28. Cerebral metabolism, cognition, and functional abilities in Alzheimer disease. J Geriatr Psychiatry Neurol. 2011 Sep; 24(3):127-34. Melrose RJ, Ettenhofer ML, Harwood D, Achamallah N, Campa O, Mandelkern M, Sultzer DL. PMID: 21856969.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    29. Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD. Am J Psychiatry. 2011 Aug; 168(8):831-9. Vigen CL, Mack WJ, Keefe RS, Sano M, Sultzer DL, Stroup TS, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, Tariot PN, Zheng L, Schneider LS. PMID: 21572163; PMCID: PMC3310182.
      View in: PubMed   Mentions: 78     Fields:    Translation:Humans
    30. Solanezumab for Alzheimer's disease. Expert Opin Biol Ther. 2011 Jun; 11(6):787-98. Samadi H, Sultzer D. PMID: 21504387.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    31. The relationship between cognitive impairment and diabetes self-management in a population-based community sample of older adults with Type 2 diabetes. J Behav Med. 2012 Apr; 35(2):190-9. Feil DG, Zhu CW, Sultzer DL. PMID: 21503710.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    32. Executive deficits and regional brain metabolism in Alzheimer's disease. Int J Geriatr Psychiatry. 2010 Nov; 25(11):1150-8. Woo BK, Harwood DG, Melrose RJ, Mandelkern MA, Campa OM, Walston A, Sultzer DL. PMID: 20069587.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    33. Effect of memantine treatment on regional cortical metabolism in Alzheimer's disease. Am J Geriatr Psychiatry. 2010 Jul; 18(7):606-14. Sultzer DL, Melrose RJ, Harwood DG, Campa O, Mandelkern MA. PMID: 20220580.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    34. The neural correlates of naming and fluency deficits in Alzheimer's disease: an FDG-PET study. Int J Geriatr Psychiatry. 2009 Aug; 24(8):885-93. Melrose RJ, Campa OM, Harwood DG, Osato S, Mandelkern MA, Sultzer DL. PMID: 19296551; PMCID: PMC2743128.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    35. Clinical symptom responses to atypical antipsychotic medications in Alzheimer's disease: phase 1 outcomes from the CATIE-AD effectiveness trial. Am J Psychiatry. 2008 Jul; 165(7):844-54. Sultzer DL, Davis SM, Tariot PN, Dagerman KS, Lebowitz BD, Lyketsos CG, Rosenheck RA, Hsiao JK, Lieberman JA, Schneider LS, CATIE-AD Study Group. PMID: 18519523; PMCID: PMC2714365.
      View in: PubMed   Mentions: 97     Fields:    Translation:Humans
    36. Quality indicators for the care of dementia in vulnerable elders. J Am Geriatr Soc. 2007 Oct; 55 Suppl 2:S293-301. Feil DG, MacLean C, Sultzer D. PMID: 17910550.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    37. Positron emission tomography metabolic correlates of apathy in Alzheimer disease. Arch Neurol. 2007 Jul; 64(7):1015-20. Marshall GA, Monserratt L, Harwood D, Mandelkern M, Cummings JL, Sultzer DL. PMID: 17620493.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    38. Memory impairment among primary care veterans. Aging Ment Health. 2007 Jul; 11(4):444-50. Chodosh J, Sultzer DL, Lee ML, Hahn TJ, Reuben DB, Yano EM, Mittman BS, Rubenstein LZ. PMID: 17612808.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Frontal lobe hypometabolism and impaired insight in Alzheimer disease. Am J Geriatr Psychiatry. 2005 Nov; 13(11):934-41. Harwood DG, Sultzer DL, Feil D, Monserratt L, Freedman E, Mandelkern MA. PMID: 16286436.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    40. Psychosis and antipsychotic medications in Alzheimer's disease: clinical management and research perspectives. Dement Geriatr Cogn Disord. 2004; 17(1-2):78-90. Sultzer DL. PMID: 14566100.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    41. Valproate-induced hyperammonemia as a cause of altered mental status. Am J Geriatr Psychiatry. 2002 Jul-Aug; 10(4):476-8. Feil D, Chuang K, Sultzer DL. PMID: 12095907.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    42. "Life is not worth living": hopelessness in Alzheimer's disease. J Geriatr Psychiatry Neurol. 2002; 15(1):38-43. Harwood DG, Sultzer DL. PMID: 11936242.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
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