Loading...

Goulding, Celia

Title(s)Chair of Molecular Biology & Biochemistry, Molecular Biology & Biochemistry
Phone(949) 824-0337
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    T32 for Training in Microbiology and Infectious Diseases
    NIH/NIAID T32AI141346Aug 19, 2019 - Jul 31, 2024
    Role: Co-Principal Investigator
    Molecular mechanisms of antibacterial CDI toxin activation
    NIH/NIGMS R01GM117373Aug 1, 2016 - Jun 30, 2020
    Role: Co-Principal Investigator
    Structure-function analysis of polymorphic CDI toxin-immunity protein complexes a
    NIH/NIGMS U01GM102318Sep 1, 2012 - Aug 31, 2017
    Role: Principal Investigator
    Structural and Functional Analyses of Toxin-Antitoxin Protein Complexes From Bact
    NIH/NIAID R21AI099687Feb 1, 2012 - Jan 31, 2014
    Role: Principal Investigator
    Structural And Biochemical Characterization Of A Novel Mycobacterial Heme Uptake
    NIH/NIAID R01AI081161Jun 15, 2009 - May 31, 2014
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Gucinski GC, Michalska K, Garza-Sánchez F, Eschenfeldt WH, Stols L, Nguyen JY, Goulding CW, Joachimiak A, Hayes CS. Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins. Structure. 2019 Sep 06. PMID: 31515004.
      View in: PubMed
    2. Lepore R, Kryshtafovych A, Alahuhta M, Arora Veraszto H, Bomble YJ, Bufton JC, Bullock AN, Caba C, Cao H, Davies OR, Desfosses A, Dunne M, Fidelis K, Goulding CW, Gurusaran M, Gutsche I, Harding CJ, Hartmann MD, Hayes CS, Joachimiak A, Leiman PG, Loppnau P, Lovering AL, Lunin VV, Michalska K, Mir-Sanchis I, Mitra A, Moult J, Phillips GN, Pinkas DM, Rice PA, Tong Y, Topf M, Walton JD, Schwede T. Target highlights in CASP13: experimental target structures through the eyes of their authors. Proteins. 2019 Aug 23. PMID: 31442339.
      View in: PubMed
    3. Tiwari S, Casey R, Goulding CW, Hingley-Wilson S, Jacobs WR. Infect and Inject: How Mycobacterium tuberculosis Exploits Its Major Virulence-Associated Type VII Secretion System, ESX-1. Microbiol Spectr. 2019 May; 7(3). PMID: 31172908.
      View in: PubMed
    4. Chao A, Goulding CW. A Single Mutation in the Mycobacterium tuberculosis Heme-Degrading Protein, MhuD, Results in Different Products. Biochemistry. 2019 Feb 12; 58(6):489-492. PMID: 30605595.
      View in: PubMed
    5. Chao A, Sieminski PJ, Owens CP, Goulding CW. Iron Acquisition in Mycobacterium tuberculosis. Chem Rev. 2018 Nov 26. PMID: 30474981.
      View in: PubMed
    6. Thakuri B, Graves AB, Chao A, Johansen SL, Goulding CW, Liptak MD. The affinity of MhuD for heme is consistent with a heme degrading function in vivo. Metallomics. 2018 Nov 14; 10(11):1560-1563. PMID: 30239544.
      View in: PubMed
    7. Michalska K, Quan Nhan D, Willett JLE, Stols LM, Eschenfeldt WH, Jones AM, Nguyen JY, Koskiniemi S, Low DA, Goulding CW, Joachimiak A, Hayes CS. Functional plasticity of antibacterial EndoU toxins. Mol Microbiol. 2018 08; 109(4):509-527. PMID: 29923643.
      View in: PubMed
    8. Cuthbert BJ, Burley KH, Goulding CW. Introducing the new bacterial branch of the RNase A superfamily. RNA Biol. 2018 01 02; 15(1):9-12. PMID: 29099294.
      View in: PubMed
    9. Kryshtafovych A, Albrecht R, Baslé A, Bule P, Caputo AT, Carvalho AL, Chao KL, Diskin R, Fidelis K, Fontes CMGA, Fredslund F, Gilbert HJ, Goulding CW, Hartmann MD, Hayes CS, Herzberg O, Hill JC, Joachimiak A, Kohring GW, Koning RI, Lo Leggio L, Mangiagalli M, Michalska K, Moult J, Najmudin S, Nardini M, Nardone V, Ndeh D, Nguyen TH, Pintacuda G, Postel S, van Raaij MJ, Roversi P, Shimon A, Singh AK, Sundberg EJ, Tars K, Zitzmann N, Schwede T. Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016). Proteins. 2018 03; 86 Suppl 1:27-50. PMID: 28960539.
      View in: PubMed
    10. Michalska K, Gucinski GC, Garza-Sánchez F, Johnson PM, Stols LM, Eschenfeldt WH, Babnigg G, Low DA, Goulding CW, Joachimiak A, Hayes CS. Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs. Nucleic Acids Res. 2017 Sep 29; 45(17):10306-10320. PMID: 28973472.
      View in: PubMed
    11. Morrissette NS, Goulding CW. From B to A: making an essential cofactor in a human parasite. Biochem J. 2017 08 30; 474(18):3089-3092. PMID: 28860337.
      View in: PubMed
    12. Burley K, Goulding CW. Protein engineering: Redirecting membrane machinery. Nat Chem Biol. 2017 08 18; 13(9):927-928. PMID: 28820876.
      View in: PubMed
    13. Batot G, Michalska K, Ekberg G, Irimpan EM, Joachimiak G, Jedrzejczak R, Babnigg G, Hayes CS, Joachimiak A, Goulding CW. The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily. Nucleic Acids Res. 2017 May 19; 45(9):5013-5025. PMID: 28398546.
      View in: PubMed
    14. Balderas MA, Nguyen CT, Terwilliger A, Keitel WA, Iniguez A, Torres R, Palacios F, Goulding CW, Maresso AW. Progress toward the Development of a NEAT Protein Vaccine for Anthrax Disease. Infect Immun. 2016 Dec; 84(12):3408-3422. PMID: 27647868.
      View in: PubMed
    15. Costa DL, Namasivayam S, Amaral EP, Arora K, Chao A, Mittereder LR, Maiga M, Boshoff HI, Barry CE, Goulding CW, Andrade BB, Sher A. Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes. MBio. 2016 10 25; 7(5). PMID: 27795400.
      View in: PubMed
    16. Johnson PM, Beck CM, Morse RP, Garza-Sánchez F, Low DA, Hayes CS, Goulding CW. Unraveling the essential role of CysK in CDI toxin activation. Proc Natl Acad Sci U S A. 2016 08 30; 113(35):9792-7. PMID: 27531961.
      View in: PubMed
    17. Johnson PM, Gucinski GC, Garza-Sánchez F, Wong T, Hung LW, Hayes CS, Goulding CW. Functional Diversity of Cytotoxic tRNase/Immunity Protein Complexes from Burkholderia pseudomallei. J Biol Chem. 2016 09 09; 291(37):19387-400. PMID: 27445337.
      View in: PubMed
    18. Diaz-Ochoa VE, Lam D, Lee CS, Klaus S, Behnsen J, Liu JZ, Chim N, Nuccio SP, Rathi SG, Mastroianni JR, Edwards RA, Jacobo CM, Cerasi M, Battistoni A, Ouellette AJ, Goulding CW, Chazin WJ, Skaar EP, Raffatellu M. Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration. Cell Host Microbe. 2016 Jun 08; 19(6):814-25. PMID: 27281571; PMCID: PMC4901528 [Available on 06/08/17].
    19. Matsui T, Nambu S, Goulding CW, Takahashi S, Fujii H, Ikeda-Saito M. Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation. Proc Natl Acad Sci U S A. 2016 Apr 05; 113(14):3779-84. PMID: 27006503.
      View in: PubMed
    20. Morse RP, Willett JL, Johnson PM, Zheng J, Credali A, Iniguez A, Nowick JS, Hayes CS, Goulding CW. Diversification of ß-Augmentation Interactions between CDI Toxin/Immunity Proteins. J Mol Biol. 2015 Nov 20; 427(23):3766-84. PMID: 26449640.
      View in: PubMed
    21. Willett JL, Ruhe ZC, Goulding CW, Low DA, Hayes CS. Contact-Dependent Growth Inhibition (CDI) and CdiB/CdiA Two-Partner Secretion Proteins. J Mol Biol. 2015 Nov 20; 427(23):3754-65. PMID: 26388411.
      View in: PubMed
    22. Chim N, Torres R, Liu Y, Capri J, Batot G, Whitelegge JP, Goulding CW. The Structure and Interactions of Periplasmic Domains of Crucial MmpL Membrane Proteins from Mycobacterium tuberculosis. Chem Biol. 2015 Aug 20; 22(8):1098-107. PMID: 26278184.
      View in: PubMed
    23. Behera RK, Torres R, Tosha T, Bradley JM, Goulding CW, Theil EC. Fe(2+) substrate transport through ferritin protein cage ion channels influences enzyme activity and biomineralization. J Biol Inorg Chem. 2015 Sep; 20(6):957-69. PMID: 26202907.
      View in: PubMed
    24. Tan K, Johnson PM, Stols L, Boubion B, Eschenfeldt W, Babnigg G, Hayes CS, Joachimiak A, Goulding CW. The structure of a contact-dependent growth-inhibition (CDI) immunity protein from Neisseria meningitidis MC58. Acta Crystallogr F Struct Biol Commun. 2015 Jun; 71(Pt 6):702-9. PMID: 26057799.
      View in: PubMed
    25. Graves AB, Morse RP, Chao A, Iniguez A, Goulding CW, Liptak MD. Crystallographic and spectroscopic insights into heme degradation by Mycobacterium tuberculosis MhuD. Inorg Chem. 2014 Jun 16; 53(12):5931-40. PMID: 24901029.
      View in: PubMed
    26. Contreras H, Joens MS, McMath LM, Le VP, Tullius MV, Kimmey JM, Bionghi N, Horwitz MA, Fitzpatrick JA, Goulding CW. Characterization of a Mycobacterium tuberculosis nanocompartment and its potential cargo proteins. J Biol Chem. 2014 Jun 27; 289(26):18279-89. PMID: 24855650.
      View in: PubMed
    27. Beck CM, Morse RP, Cunningham DA, Iniguez A, Low DA, Goulding CW, Hayes CS. CdiA from Enterobacter cloacae delivers a toxic ribosomal RNase into target bacteria. Structure. 2014 May 06; 22(5):707-18. PMID: 24657090.
      View in: PubMed
    28. Torres R, Lan B, Latif Y, Chim N, Goulding CW. Structural snapshots along the reaction pathway of Yersinia pestis RipA, a putative butyryl-CoA transferase. Acta Crystallogr D Biol Crystallogr. 2014 Apr; 70(Pt 4):1074-85. PMID: 24699651.
      View in: PubMed
    29. Contreras H, Chim N, Credali A, Goulding CW. Heme uptake in bacterial pathogens. Curr Opin Chem Biol. 2014 Apr; 19:34-41. PMID: 24780277.
      View in: PubMed
    30. Chim N, Johnson PM, Goulding CW. Insights into redox sensing metalloproteins in Mycobacterium tuberculosis. J Inorg Biochem. 2014 Apr; 133:118-26. PMID: 24314844.
      View in: PubMed
    31. Chim N, Harmston CA, Guzman DJ, Goulding CW. Structural and biochemical characterization of the essential DsbA-like disulfide bond forming protein from Mycobacterium tuberculosis. BMC Struct Biol. 2013 Oct 18; 13:23. PMID: 24134223.
      View in: PubMed
    32. Pham JD, Chim N, Goulding CW, Nowick JS. Structures of oligomers of a peptide from ß-amyloid. J Am Chem Soc. 2013 Aug 21; 135(33):12460-7. PMID: 23927812.
      View in: PubMed
    33. Owens CP, Chim N, Goulding CW. Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target. Future Med Chem. 2013 Aug; 5(12):1391-403. PMID: 23919550.
      View in: PubMed
    34. Owens CP, Chim N, Graves AB, Harmston CA, Iniguez A, Contreras H, Liptak MD, Goulding CW. The Mycobacterium tuberculosis secreted protein Rv0203 transfers heme to membrane proteins MmpL3 and MmpL11. J Biol Chem. 2013 Jul 26; 288(30):21714-28. PMID: 23760277.
      View in: PubMed
    35. Matsui T, Nambu S, Ono Y, Goulding CW, Tsumoto K, Ikeda-Saito M. Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide. Biochemistry. 2013 May 07; 52(18):3025-7. PMID: 23600533.
      View in: PubMed
    36. Nambu S, Matsui T, Goulding CW, Takahashi S, Ikeda-Saito M. A new way to degrade heme: the Mycobacterium tuberculosis enzyme MhuD catalyzes heme degradation without generating CO. J Biol Chem. 2013 Apr 05; 288(14):10101-9. PMID: 23420845.
      View in: PubMed
    37. Honsa ES, Owens CP, Goulding CW, Maresso AW. The near-iron transporter (NEAT) domains of the anthrax hemophore IsdX2 require a critical glutamine to extract heme from methemoglobin. J Biol Chem. 2013 Mar 22; 288(12):8479-90. PMID: 23364793.
      View in: PubMed
    38. Morse RP, Nikolakakis KC, Willett JL, Gerrick E, Low DA, Hayes CS, Goulding CW. Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems. Proc Natl Acad Sci U S A. 2012 Dec 26; 109(52):21480-5. PMID: 23236156.
      View in: PubMed
    39. Ekworomadu MT, Poor CB, Owens CP, Balderas MA, Fabian M, Olson JS, Murphy F, Bakkalbasi E, Balkabasi E, Honsa ES, He C, Goulding CW, Maresso AW. Differential function of lip residues in the mechanism and biology of an anthrax hemophore. PLoS Pathog. 2012; 8(3):e1002559. PMID: 22412371.
      View in: PubMed
    40. Owens CP, Du J, Dawson JH, Goulding CW. Characterization of heme ligation properties of Rv0203, a secreted heme binding protein involved in Mycobacterium tuberculosis heme uptake. Biochemistry. 2012 Feb 21; 51(7):1518-31. PMID: 22283334.
      View in: PubMed
    41. Torres R, Chim N, Sankaran B, Pujol C, Bliska JB, Goulding CW. Structural insights into RipC, a putative citrate lyase ß subunit from a Yersinia pestis virulence operon. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jan 01; 68(Pt 1):2-7. PMID: 22232161.
      View in: PubMed
    42. Khan IH, Ravindran R, Krishnan VV, Awan IN, Rizvi SK, Saqib MA, Shahzad MI, Tahseen S, Ireton G, Goulding CW, Felgner P, DeRiemer K, Khanum A, Luciw PA. Plasma antibody profiles as diagnostic biomarkers for tuberculosis. Clin Vaccine Immunol. 2011 Dec; 18(12):2148-53. PMID: 21976221.
      View in: PubMed
    43. Torres R, Swift RV, Chim N, Wheatley N, Lan B, Atwood BR, Pujol C, Sankaran B, Bliska JB, Amaro RE, Goulding CW. Biochemical, structural and molecular dynamics analyses of the potential virulence factor RipA from Yersinia pestis. PLoS One. 2011; 6(9):e25084. PMID: 21966419.
      View in: PubMed
    44. Tullius MV, Harmston CA, Owens CP, Chim N, Morse RP, McMath LM, Iniguez A, Kimmey JM, Sawaya MR, Whitelegge JP, Horwitz MA, Goulding CW. Discovery and characterization of a unique mycobacterial heme acquisition system. Proc Natl Acad Sci U S A. 2011 Mar 22; 108(12):5051-6. PMID: 21383189.
      View in: PubMed
    45. Chim N, Habel JE, Johnston JM, Krieger I, Miallau L, Sankaranarayanan R, Morse RP, Bruning J, Swanson S, Kim H, Kim CY, Li H, Bulloch EM, Payne RJ, Manos-Turvey A, Hung LW, Baker EN, Lott JS, James MN, Terwilliger TC, Eisenberg DS, Sacchettini JC, Goulding CW. The TB Structural Genomics Consortium: a decade of progress. Tuberculosis (Edinb). 2011 Mar; 91(2):155-72. PMID: 21247804; PMCID: PMC3310434.
    46. McMath LM, Habel JE, Sankaran B, Yu M, Hung LW, Goulding CW. Crystallization and preliminary X-ray crystallographic analysis of a Mycobacterium tuberculosis ferritin homolog, BfrB. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Dec 01; 66(Pt 12):1657-61. PMID: 21139218.
      View in: PubMed
    47. Chim N, Riley R, The J, Im S, Segelke B, Lekin T, Yu M, Hung LW, Terwilliger T, Whitelegge JP, Goulding CW. An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis. J Mol Biol. 2010 Mar 12; 396(5):1211-26. PMID: 20060836.
      View in: PubMed
    48. Chim N, Iniguez A, Nguyen TQ, Goulding CW. Unusual diheme conformation of the heme-degrading protein from Mycobacterium tuberculosis. J Mol Biol. 2010 Jan 22; 395(3):595-608. PMID: 19917297.
      View in: PubMed
    49. Chim N, McMath LM, Beeby M, Goulding CW. Advances in Mycobacterium tuberculosis structural genomics: investigating potential chinks in the armor of a deadly pathogen. Infect Disord Drug Targets. 2009 Nov; 9(5):475-92. PMID: 19594421.
      View in: PubMed
    50. Fox BG, Goulding C, Malkowski MG, Stewart L, Deacon A. Structural genomics: from genes to structures with valuable materials and many questions in between. Nat Methods. 2008 Feb; 5(2):129-32. PMID: 18235432.
      View in: PubMed
    51. Khan IH, Ravindran R, Yee J, Ziman M, Lewinsohn DM, Gennaro ML, Flynn JL, Goulding CW, DeRiemer K, Lerche NW, Luciw PA. Profiling antibodies to Mycobacterium tuberculosis by multiplex microbead suspension arrays for serodiagnosis of tuberculosis. Clin Vaccine Immunol. 2008 Mar; 15(3):433-8. PMID: 18077619.
      View in: PubMed
    52. Murillo AC, Li HY, Alber T, Baker EN, Berger JM, Cherney LT, Cherney MM, Cho YS, Eisenberg D, Garen CR, Goulding CW, Hung LW, Ioerger TR, Jacobs WR, James MN, Kim C, Krieger I, Lott JS, Sankaranarayanan R, Segelke BW, Terwilliger TC, Wang F, Wang S, Sacchettini JC. High throughput crystallography of TB drug targets. Infect Disord Drug Targets. 2007 Jun; 7(2):127-39. PMID: 17970224.
      View in: PubMed
    53. White EL, Southworth K, Ross L, Cooley S, Gill RB, Sosa MI, Manouvakhova A, Rasmussen L, Goulding C, Eisenberg D, Fletcher TM. A novel inhibitor of Mycobacterium tuberculosis pantothenate synthetase. J Biomol Screen. 2007 Feb; 12(1):100-5. PMID: 17175524.
      View in: PubMed
    54. Goulding CW, Bowers PM, Segelke B, Lekin T, Kim CY, Terwilliger TC, Eisenberg D. The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function. J Mol Biol. 2007 Jan 12; 365(2):275-83. PMID: 17064730.
      View in: PubMed
    55. Strong M, Goulding CW. Structural proteomics and computational analysis of a deadly pathogen: combating Mycobacterium tuberculosis from multiple fronts. Methods Biochem Anal. 2006; 49:245-69. PMID: 16929683.
      View in: PubMed
    56. Goulding CW, Apostol MI, Sawaya MR, Phillips M, Parseghian A, Eisenberg D. Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme. J Mol Biol. 2005 May 27; 349(1):61-72. PMID: 15876368.
      View in: PubMed
    57. Goulding CW, Apostol MI, Gleiter S, Parseghian A, Bardwell J, Gennaro M, Eisenberg D. Gram-positive DsbE proteins function differently from Gram-negative DsbE homologs. A structure to function analysis of DsbE from Mycobacterium tuberculosis. J Biol Chem. 2004 Jan 30; 279(5):3516-24. PMID: 14597624.
      View in: PubMed
    58. Hsu T, Hingley-Wilson SM, Chen B, Chen M, Dai AZ, Morin PM, Marks CB, Padiyar J, Goulding C, Gingery M, Eisenberg D, Russell RG, Derrick SC, Collins FM, Morris SL, King CH, Jacobs WR. The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12420-5. PMID: 14557547; PMCID: PMC218773.
    59. Goulding CW, Perry LJ, Anderson D, Sawaya MR, Cascio D, Apostol MI, Chan S, Parseghian A, Wang SS, Wu Y, Cassano V, Gill HS, Eisenberg D. Structural genomics of Mycobacterium tuberculosis: a preliminary report of progress at UCLA. Biophys Chem. 2003 Sep; 105(2-3):361-70. PMID: 14499904.
      View in: PubMed
    60. Goulding CW, Perry LJ. Protein production in Escherichia coli for structural studies by X-ray crystallography. J Struct Biol. 2003 Apr; 142(1):133-43. PMID: 12718925.
      View in: PubMed
    61. Terwilliger TC, Park MS, Waldo GS, Berendzen J, Hung LW, Kim CY, Smith CV, Sacchettini JC, Bellinzoni M, Bossi R, De Rossi E, Mattevi A, Milano A, Riccardi G, Rizzi M, Roberts MM, Coker AR, Fossati G, Mascagni P, Coates AR, Wood SP, Goulding CW, Apostol MI, Anderson DH, Gill HS, Eisenberg DS, Taneja B, Mande S, Pohl E, Lamzin V, Tucker P, Wilmanns M, Colovos C, Meyer-Klaucke W, Munro AW, McLean KJ, Marshall KR, Leys D, Yang JK, Yoon HJ, Lee BI, Lee MG, Kwak JE, Han BW, Lee JY, Baek SH, Suh SW, Komen MM, Arcus VL, Baker EN, Lott JS, Jacobs W, Alber T, Rupp B. The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis (Edinb). 2003; 83(4):223-49. PMID: 12906835.
      View in: PubMed
    62. Goulding CW, Parseghian A, Sawaya MR, Cascio D, Apostol MI, Gennaro ML, Eisenberg D. Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution. Protein Sci. 2002 Dec; 11(12):2887-93. PMID: 12441386.
      View in: PubMed
    63. Goulding CW, Sawaya MR, Parseghian A, Lim V, Eisenberg D, Missiakas D. Thiol-disulfide exchange in an immunoglobulin-like fold: structure of the N-terminal domain of DsbD. Biochemistry. 2002 Jun 04; 41(22):6920-7. PMID: 12033924.
      View in: PubMed
    64. Goulding CW, Apostol M, Anderson DH, Gill HS, Smith CV, Kuo MR, Yang JK, Waldo GS, Suh SW, Chauhan R, Kale A, Bachhawat N, Mande SC, Johnston JM, Lott JS, Baker EN, Arcus VL, Leys D, McLean KJ, Munro AW, Berendzen J, Sharma V, Park MS, Eisenberg D, Sacchettini J, Alber T, Rupp B, Jacobs W, Terwilliger TC. The TB structural genomics consortium: providing a structural foundation for drug discovery. Curr Drug Targets Infect Disord. 2002 Jun; 2(2):121-41. PMID: 12462144.
      View in: PubMed
    65. Hindiyeh M, Goulding C, Morgan H, Kenyon B, Langer J, Fox L, Dean G, Woolstenhulme D, Turnbow A, Billetdeaux E, Shakib S, Gordon C, Powers A, Vardeny G, Johnson M, Skodack-Jones L, Carroll K. Evaluation of BioStar FLU OIA assay for rapid detection of influenza A and B viruses in respiratory specimens. J Clin Virol. 2000 Aug; 17(2):119-26. PMID: 10942092.
      View in: PubMed
    66. Goulding CW, Giuliano AE, Cabot MC. SDZ PSC 833 the drug resistance modulator activates cellular ceramide formation by a pathway independent of P-glycoprotein. Cancer Lett. 2000 Feb 28; 149(1-2):143-51. PMID: 10737718.
      View in: PubMed
    67. Goulding CW, Matthews RG. Cobalamin-dependent methionine synthase from Escherichia coli: involvement of zinc in homocysteine activation. Biochemistry. 1997 Dec 16; 36(50):15749-57. PMID: 9398304.
      View in: PubMed
    68. Matthews RG, Goulding CW. Enzyme-catalyzed methyl transfers to thiols: the role of zinc. Curr Opin Chem Biol. 1997 Oct; 1(3):332-9. PMID: 9667865.
      View in: PubMed
    69. Goulding CW, Postigo D, Matthews RG. Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine. Biochemistry. 1997 Jul 01; 36(26):8082-91. PMID: 9201956.
      View in: PubMed