Pablo Lara-Gonzalez

Title(s)Assistant Professor, Developmental & Cell Biology
SchoolSchool of Biological Sciences
AddressIrvine CA 92697
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Phospho-KNL-1 recognition by a TPR domain targets the BUB-1-BUB-3 complex to C. elegans kinetochores. bioRxiv. 2024 Feb 11. Houston J, Vissotsky C, Deep A, Hakozaki H, Crews E, Oegema K, Corbett KD, Lara-Gonzalez P, Kim T, Desai A. PMID: 38370671; PMCID: PMC10871365.
      View in: PubMed   Mentions:
    2. Cyclin B3 is a dominant fast-acting cyclin that drives rapid early embryonic mitoses. bioRxiv. 2023 Aug 11. Lara-Gonzalez P, Variyar S, Budrewicz J, Schlientz A, Varshney N, Bellaart A, Moghareh S, Nguyen ACN, Oegema K, Desai A. PMID: 37609212; PMCID: PMC10441424.
      View in: PubMed   Mentions:
    3. BUB-1-bound PLK-1 directs CDC-20 kinetochore recruitment to ensure timely embryonic mitoses. Curr Biol. 2023 06 05; 33(11):2291-2299.e10. Houston J, Ohta M, Gómez-Cavazos JS, Deep A, Corbett KD, Oegema K, Lara-Gonzalez P, Kim T, Desai A. PMID: 37137308; PMCID: PMC10270731.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    4. Nuclear-enriched protein phosphatase 4 ensures outer kinetochore assembly prior to nuclear dissolution. J Cell Biol. 2023 03 06; 222(3). Rocha H, Simões PA, Budrewicz J, Lara-Gonzalez P, Carvalho AX, Dumont J, Desai A, Gassmann R. PMID: 36719399; PMCID: PMC9930252.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. TMEM161B modulates radial glial scaffolding in neocortical development. Proc Natl Acad Sci U S A. 2023 01 24; 120(4):e2209983120. Wang L, Heffner C, Vong KI, Barrows C, Ha YJ, Lee S, Lara-Gonzalez P, Jhamb I, Van Der Meer D, Loughnan R, Parker N, Sievert D, Mittal S, Issa MY, Andreassen OA, Dale A, Dobyns WB, Zaki MS, Murray SA, Gleeson JG. PMID: 36669109; PMCID: PMC9942823.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain. Mol Cell. 2022 01 06; 82(1):90-105.e13. Ferguson CJ, Urso O, Bodrug T, Gassaway BM, Watson ER, Prabu JR, Lara-Gonzalez P, Martinez-Chacin RC, Wu DY, Brigatti KW, Puffenberger EG, Taylor CM, Haas-Givler B, Jinks RN, Strauss KA, Desai A, Gabel HW, Gygi SP, Schulman BA, Brown NG, Bonni A. PMID: 34942119; PMCID: PMC8741739.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. Spindle assembly checkpoint activation and silencing at kinetochores. Semin Cell Dev Biol. 2021 09; 117:86-98. Lara-Gonzalez P, Pines J, Desai A. PMID: 34210579; PMCID: PMC8406419.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    8. The N-terminal tail of C. elegans CENP-A interacts with KNL-2 and is essential for centromeric chromatin assembly. Mol Biol Cell. 2021 06 01; 32(12):1193-1201. de Groot C, Houston J, Davis B, Gerson-Gurwitz A, Monen J, Lara-Gonzalez P, Oegema K, Shiau AK, Desai A. PMID: 33852350; PMCID: PMC8351560.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    9. The PHLPP1 N-Terminal Extension is a Mitotic Cdk1 Substrate and Controls an Interactome Switch. Mol Cell Biol. 2021 Jan 04. Kawashima AT, Wong C, Lordén G, King CC, Lara-Gonzalez P, Desai A, Gingras AC, Newton AC. PMID: 33397691; PMCID: PMC8088274.
      View in: PubMed   Mentions: 3     Fields:    
    10. A tripartite mechanism catalyzes Mad2-Cdc20 assembly at unattached kinetochores. Science. 2021 01 01; 371(6524):64-67. Lara-Gonzalez P, Kim T, Oegema K, Corbett K, Desai A. PMID: 33384372; PMCID: PMC8191211.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    11. BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes. Elife. 2020 12 23; 9. Bel Borja L, Soubigou F, Taylor SJP, Fraguas Bringas C, Budrewicz J, Lara-Gonzalez P, Sorensen Turpin CG, Bembenek JN, Cheerambathur DK, Pelisch F. PMID: 33355089; PMCID: PMC7787666.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    12. Rashomon at the kinetochore: Function(s) of the Mad1-cyclin B1 complex. J Cell Biol. 2020 08 03; 219(8). Houston J, Lara-Gonzalez P, Desai A. PMID: 32614383; PMCID: PMC7401815.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C. Dev Cell. 2019 11 04; 51(3):313-325.e10. Lara-Gonzalez P, Moyle MW, Budrewicz J, Mendoza-Lopez J, Oegema K, Desai A. PMID: 31588029; PMCID: PMC7778526.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    14. Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nat Chem Biol. 2019 05; 15(5):453-462. Chen AL, Lum KM, Lara-Gonzalez P, Ogasawara D, Cognetta AB, To A, Parsons WH, Simon GM, Desai A, Petrascheck M, Bar-Peled L, Cravatt BF. PMID: 30911178; PMCID: PMC6548519.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    15. CFI-400945 is not a selective cellular PLK4 inhibitor. Proc Natl Acad Sci U S A. 2018 11 13; 115(46):E10808-E10809. Oegema K, Davis RL, Lara-Gonzalez P, Desai A, Shiau AK. PMID: 30377272; PMCID: PMC6243232.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    16. Employing the one-cell C. elegans embryo to study cell division processes. Methods Cell Biol. 2018; 144:185-231. Hattersley N, Lara-Gonzalez P, Cheerambathur D, Gomez-Cavazos JS, Kim T, Prevo B, Khaliullin R, Lee KY, Ohta M, Green R, Oegema K, Desai A. PMID: 29804670; PMCID: PMC6374127.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    17. Taming the Beast: Control of APC/CCdc20-Dependent Destruction. Cold Spring Harb Symp Quant Biol. 2017; 82:111-121. Lara-Gonzalez P, Kim T, Desai A. PMID: 29133301; PMCID: PMC6374126.
      View in: PubMed   Mentions: 6     Fields:    
    18. A toolkit for GFP-mediated tissue-specific protein degradation in C. elegans. Development. 2017 07 15; 144(14):2694-2701. Wang S, Tang NH, Lara-Gonzalez P, Zhao Z, Cheerambathur DK, Prevo B, Chisholm AD, Desai A, Oegema K. PMID: 28619826; PMCID: PMC5536931.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    19. Kinetochores accelerate or delay APC/C activation by directing Cdc20 to opposing fates. Genes Dev. 2017 06 01; 31(11):1089-1094. Kim T, Lara-Gonzalez P, Prevo B, Meitinger F, Cheerambathur DK, Oegema K, Desai A. PMID: 28698300; PMCID: PMC5538432.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    20. Correction: Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans. J Cell Biol. 2016 Mar 14; 212(6):737. Kim T, Moyle MW, Lara-Gonzalez P, De Groot C, Oegema K, Desai A. PMID: 26953348; PMCID: PMC4792070.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    21. Natural Loss of Mps1 Kinase in Nematodes Uncovers a Role for Polo-like Kinase 1 in Spindle Checkpoint Initiation. Cell Rep. 2015 Jul 07; 12(1):58-65. Espeut J, Lara-Gonzalez P, Sassine M, Shiau AK, Desai A, Abrieu A. PMID: 26119738; PMCID: PMC4668945.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    22. Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans. J Cell Biol. 2015 May 25; 209(4):507-17. Kim T, Moyle MW, Lara-Gonzalez P, De Groot C, Oegema K, Desai A. PMID: 25987605; PMCID: PMC4442812.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    23. The spindle assembly checkpoint. Curr Biol. 2012 Nov 20; 22(22):R966-80. Lara-Gonzalez P, Westhorpe FG, Taylor SS. PMID: 23174302.
      View in: PubMed   Mentions: 392     Fields:    Translation:AnimalsCells
    24. Cohesion fatigue explains why pharmacological inhibition of the APC/C induces a spindle checkpoint-dependent mitotic arrest. PLoS One. 2012; 7(11):e49041. Lara-Gonzalez P, Taylor SS. PMID: 23145059; PMCID: PMC3492190.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    25. BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner. J Cell Sci. 2011 Dec 15; 124(Pt 24):4332-45. Lara-Gonzalez P, Scott MI, Diez M, Sen O, Taylor SS. PMID: 22193957; PMCID: PMC3258114.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    26. p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit. J Cell Sci. 2011 Nov 15; 124(Pt 22):3905-16. Westhorpe FG, Tighe A, Lara-Gonzalez P, Taylor SS. PMID: 22100920; PMCID: PMC3225272.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCells
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