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Sub-chronic nicotine exposure influences methamphetamine self-administration and dopamine overflow in a sex-and genotype-dependent manner in humanized CHRNA6 3'-UTR SNP (rs2304297) adolescent rats. Front Pharmacol. 2024; 15:1445303.
Carreño D, Facundo A, Cardenas A, Lotfipour S. PMID: 39206256; PMCID: PMC11349519.
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Hypersensitivity of the nicotinic acetylcholine receptor subunit (CHRNA2L9'S/L9'S) in female adolescent mice produces deficits in nicotine-induced facilitation of hippocampal-dependent learning and memory. Neurobiol Learn Mem. 2024 Sep; 213:107959.
Wells AC, Mojica C, Lotfipour S. PMID: 38964600.
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Animals
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Dopamine and Norepinephrine Tissue Levels in the Developing Limbic Brain Are Impacted by the Human CHRNA6 3'-UTR Single-Nucleotide Polymorphism (rs2304297) in Rats. Int J Mol Sci. 2024 Mar 26; 25(7).
Carreño D, Facundo A, Nguyen MTT, Lotfipour S. PMID: 38612487; PMCID: PMC11011259.
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HumansAnimals
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Prenatal nicotine exposure during pregnancy results in adverse neurodevelopmental alterations and neurobehavioral deficits. Adv Drug Alcohol Res. 2023; 3:11628.
Wells AC, Lotfipour S. PMID: 38389806; PMCID: PMC10880762.
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3
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Male and Female Sprague Dawley Rats Exhibit Equivalent Natural Reward, Nicotine Self-Administration, Extinction, and Reinstatement During Adolescent-Initiated Behaviors. Nicotine Tob Res. 2023 04 06; 25(5):1039-1046.
Carreño D, Lotfipour S. PMID: 36208287.
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3 Fields:
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Animals
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Nicotine on the developing brain. Pharmacol Res. 2023 04; 190:106716.
Castro EM, Lotfipour S, Leslie FM. PMID: 36868366; PMCID: PMC10392865.
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5 Fields:
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Humans
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Sex- and genotype-dependent nicotine plus cue-primed reinstatement is enhanced in adolescent Sprague Dawley rats containing the human CHRNA6 3'-UTR polymorphism (rs2304297). Front Psychiatry. 2022; 13:1064211.
Carreño D, Lotfipour S. PMID: 36704741; PMCID: PMC9872558.
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Antibiotic Knockdown of Gut Bacteria Sex-Dependently Enhances Intravenous Fentanyl Self-Administration in Adult Sprague Dawley Rats. Int J Mol Sci. 2022 Dec 27; 24(1).
Ren M, Lotfipour S. PMID: 36613853; PMCID: PMC9820294.
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2 Fields:
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Animals
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Age- and Sex-Dependent Nicotine Pretreatment Effects on the Enhancement of Methamphetamine Self-administration in Sprague-Dawley Rats. Nicotine Tob Res. 2022 07 13; 24(8):1186-1192.
Cardenas A, Lotfipour S. PMID: 34669941; PMCID: PMC9653006.
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6 Fields:
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Animals
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Dose- and Sex-Dependent Bidirectional Relationship between Intravenous Fentanyl Self-Administration and Gut Microbiota. Microorganisms. 2022 May 30; 10(6).
Ren M, Lotfipour S. PMID: 35744645; PMCID: PMC9229572.
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3
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Sex- and Genotype-Dependent Nicotine-Induced Behaviors in Adolescent Rats with a Human Polymorphism (rs2304297) in the 3'-UTR of the CHRNA6 Gene. Int J Mol Sci. 2022 Mar 15; 23(6).
Cardenas A, Bai Y, Hajy Heydary Y, Li J, Leslie FM, Lotfipour S. PMID: 35328565; PMCID: PMC8948824.
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2 Fields:
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HumansAnimals
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Unique effects of nicotine across the lifespan. Pharmacol Biochem Behav. 2022 03; 214:173343.
Ren M, Lotfipour S, Leslie F. PMID: 35122768; PMCID: PMC8904294.
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9 Fields:
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Humans
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Early adolescent subchronic low-dose nicotine exposure increases subsequent cocaine and fentanyl self-administration in Sprague-Dawley rats. Behav Pharmacol. 2021 02 01; 32(1):86-91.
Cardenas A, Martinez M, Saenz Mejia A, Lotfipour S. PMID: 32960853; PMCID: PMC7790845.
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11 Fields:
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Animals
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The role of the gut microbiome in opioid use. Behav Pharmacol. 2020 04; 31(2&3):113-121.
Ren M, Lotfipour S. PMID: 31895059; PMCID: PMC7908675.
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21 Fields:
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HumansAnimals
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Specificity of a rodent alpha(α)6 nicotinic acetylcholine receptor subunit antibody. Psychopharmacology (Berl). 2020 01; 237(1):283-285.
Cardenas A, Elabd M, Lotfipour S. PMID: 31786649; PMCID: PMC6954311.
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2 Fields:
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Prenatal nicotine sex-dependently alters adolescent dopamine system development. Transl Psychiatry. 2019 11 18; 9(1):304.
Dwyer JB, Cardenas A, Franke RM, Chen Y, Bai Y, Belluzzi JD, Lotfipour S, Leslie FM. PMID: 31740669; PMCID: PMC6861272.
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15 Fields:
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Animals
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Nicotine Gateway Effects on Adolescent Substance Use. West J Emerg Med. 2019 Aug 20; 20(5):696-709.
Ren M, Lotfipour S. PMID: 31539325; PMCID: PMC6754186.
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52 Fields:
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Humans
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Maternal nicotine exposure effects on adolescent learning and memory are abolished in alpha(α)2* nicotinic acetylcholine receptor-null mutant mice. Neuropharmacology. 2018 06; 135:529-535.
Mojica C, Bai Y, Lotfipour S. PMID: 29677582.
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4 Fields:
Translation:
AnimalsPHPublic Health
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Morphine hyposensitivity in streptozotocin-diabetic rats: Reversal by dietary l-arginine treatment. Clin Exp Pharmacol Physiol. 2018 Jan; 45(1):42-49.
Lotfipour S, Smith MT. PMID: 28925511.
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4 Fields:
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Animals
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Optogenetic excitation of cholinergic inputs to hippocampus primes future contextual fear associations. Sci Rep. 2017 05 24; 7(1):2333.
Hersman S, Cushman J, Lemelson N, Wassum K, Lotfipour S, Fanselow MS. PMID: 28539613; PMCID: PMC5443779.
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14 Fields:
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Animals
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α2* Nicotinic acetylcholine receptors influence hippocampus-dependent learning and memory in adolescent mice. Learn Mem. 2017 06; 24(6):231-244.
Lotfipour S, Mojica C, Nakauchi S, Lipovsek M, Silverstein S, Cushman J, Tirtorahardjo J, Poulos A, Elgoyhen AB, Sumikawa K, Fanselow MS, Boulter J. PMID: 28507032; PMCID: PMC5435881.
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7 Fields:
Translation:
AnimalsCells
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Reduced-Nicotine Cigarettes in Young Smokers: Impact of Nicotine Metabolism on Nicotine Dose Effects. Neuropsychopharmacology. 2017 Jul; 42(8):1610-1618.
Faulkner P, Ghahremani DG, Tyndale RF, Cox CM, Kazanjian AS, Paterson N, Lotfipour S, Hellemann GS, Petersen N, Vigil C, London ED. PMID: 28117337; PMCID: PMC5518898.
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20 Fields:
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Humans
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Mechanisms and genetic factors underlying co-use of nicotine and alcohol or other drugs of abuse. Am J Drug Alcohol Abuse. 2017 03; 43(2):171-185.
Cross SJ, Lotfipour S, Leslie FM. PMID: 27532746; PMCID: PMC5493323.
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38 Fields:
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HumansAnimals
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α2-Null mutant mice have altered levels of neuronal activity in restricted midbrain and limbic brain regions during nicotine withdrawal as demonstrated by cfos expression. Biochem Pharmacol. 2015 Oct 15; 97(4):558-565.
Upton M, Lotfipour S. PMID: 26111579; PMCID: PMC4607355.
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11 Fields:
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AnimalsCells
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Maternal cigarette smoking during pregnancy predicts drug use via externalizing behavior in two community-based samples of adolescents. Addiction. 2014 Oct; 109(10):1718-29.
Lotfipour S, Ferguson E, Leonard G, Miettunen J, Perron M, Pike GB, Richer L, Séguin JR, Veillette S, Jarvelin MR, Moilanen I, Mäki P, Nordström T, Pausova Z, Veijola J, Paus T. PMID: 24942256.
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17 Fields:
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Humans
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Targeted deletion of the mouse α2 nicotinic acetylcholine receptor subunit gene (Chrna2) potentiates nicotine-modulated behaviors. J Neurosci. 2013 May 01; 33(18):7728-41.
Lotfipour S, Byun JS, Leach P, Fowler CD, Murphy NP, Kenny PJ, Gould TJ, Boulter J. PMID: 23637165; PMCID: PMC3831006.
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34 Fields:
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Animals
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A single administration of low-dose varenicline saturates α4β2* nicotinic acetylcholine receptors in the human brain. Neuropsychopharmacology. 2012 Jun; 37(7):1738-48.
Lotfipour S, Mandelkern M, Alvarez-Estrada M, Brody AL. PMID: 22395733; PMCID: PMC3358744.
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14 Fields:
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Humans
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Quantitative Molecular Imaging of Neuronal Nicotinic Acetylcholine Receptors in the Human Brain with A-85380 Radiotracers. Curr Med Imaging Rev. 2011 May 01; 7(2):107-112.
Lotfipour S, Mandelkern M, Brody AL. PMID: 22773924; PMCID: PMC3389797.
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6 Fields:
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The monoamine oxidase (MAO) inhibitor tranylcypromine enhances nicotine self-administration in rats through a mechanism independent of MAO inhibition. Neuropharmacology. 2011 Jul-Aug; 61(1-2):95-104.
Lotfipour S, Arnold MM, Hogenkamp DJ, Gee KW, Belluzzi JD, Leslie FM. PMID: 21419142; PMCID: PMC3105177.
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13 Fields:
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Animals
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Maternal smoking during pregnancy is associated with epigenetic modifications of the brain-derived neurotrophic factor-6 exon in adolescent offspring. Am J Med Genet B Neuropsychiatr Genet. 2010 Oct 05; 153B(7):1350-4.
Toledo-Rodriguez M, Lotfipour S, Leonard G, Perron M, Richer L, Veillette S, Pausova Z, Paus T. PMID: 20583129.
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70 Fields:
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HumansCellsPHPublic Health
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Orbitofrontal cortex and drug use during adolescence: role of prenatal exposure to maternal smoking and BDNF genotype. Arch Gen Psychiatry. 2009 Nov; 66(11):1244-52.
Lotfipour S, Ferguson E, Leonard G, Perron M, Pike B, Richer L, Séguin JR, Toro R, Veillette S, Pausova Z, Paus T. PMID: 19884612.
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49 Fields:
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HumansPHPublic Health
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Involvement of alpha1-adrenergic receptors in tranylcypromine enhancement of nicotine self-administration in rat. Psychopharmacology (Berl). 2007 Sep; 193(4):457-65.
Villégier AS, Lotfipour S, Belluzzi JD, Leslie FM. PMID: 17486319.
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20 Fields:
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Animals
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Oxycodone and morphine have distinctly different pharmacological profiles: radioligand binding and behavioural studies in two rat models of neuropathic pain. Pain. 2007 Dec 05; 132(3):289-300.
Nielsen CK, Ross FB, Lotfipour S, Saini KS, Edwards SR, Smith MT. PMID: 17467904.
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65 Fields:
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Animals
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Tranylcypromine enhancement of nicotine self-administration. Neuropharmacology. 2007 May; 52(6):1415-25.
Villégier AS, Lotfipour S, McQuown SC, Belluzzi JD, Leslie FM. PMID: 17412372.
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36 Fields:
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Animals
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Adolescent maturation of cocaine-sensitive neural mechanisms. Neuropsychopharmacology. 2007 Nov; 32(11):2279-89.
Cao J, Lotfipour S, Loughlin SE, Leslie FM. PMID: 17299504.
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33 Fields:
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Animals
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Adolescent development of forebrain stimulant responsiveness: insights from animal studies. Ann N Y Acad Sci. 2004 Jun; 1021:148-59.
Leslie FM, Loughlin SE, Wang R, Perez L, Lotfipour S, Belluzzia JD. PMID: 15251884.
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35 Fields:
Translation:
HumansAnimals