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David Jordan Adams

Title(s)Assistant Health Sciences Professor, Pediatrics
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 509-3605
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Spider venom peptides with unique fold selectively block Shaker-type potassium channels. Cell Mol Life Sci. 2025 Aug 08; 82(1):300. Kuzmenkov AI, Iunusova VA, Lushpa VA, Deyev YA, Babenko VV, Osipov DV, Berkut AA, Tytgat J, Bocharov EV, Adams DJ, Finol-Urdaneta RK, Vassilevski AA. PMID: 40778948; PMCID: PMC12334782.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Erabutoxin mutants demonstrate interface selectivity at human fetal and adult muscle-type nicotinic acetylcholine receptors. Biochem Pharmacol. 2025 Nov; 241:117189. Chan CYL, Tae HS, Koh CY, Adams DJ, Kini RM. PMID: 40716651.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Comprehensively Testing the Function of Missense Variation in the STK11 Tumour Suppressor. bioRxiv. 2025 Jul 18. Zimmerman D, Cote A, van Loggerenberg W, Gebbia M, Kishore N, Weile J, Li R, Reno C, Marsh AP, Hernandez F, Shahagadkar P, Grove L, Meier SR, Wu HJ, Fenoglio S, Ahronian L, Teng T, Waters AJ, Seward D, Taipale M, Aronson M, Richardson ME, Adams DJ, Roth FP. PMID: 40791513; PMCID: PMC12338614.
      View in: PubMed   Mentions:
    4. Parkinson's disease-linked Kir4.2 mutation R28C leads to loss of ion channel function. J Physiol. 2025 Jun; 603(12):3499-3518. Chen X, Finol-Urdaneta RK, Chen M, Sykes AM, Gao B, Iqbal J, Adams DJ, Mellick GD, Ma L. PMID: 40566643; PMCID: PMC12206441.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Validating data from multiplex assays of variant effect: A CanVIG-UK national survey of NHS clinical scientists. Am J Hum Genet. 2025 Jun 05; 112(6):1479-1488. Allen S, Garrett A, Rowlands CF, Durkie M, Burghel GJ, Robinson R, Callaway A, Field J, Frugtniet B, Palmer-Smith S, Grant J, Pagan J, McDevitt T, Snape K, Hanson H, McVeigh T, Adams DJ, Findlay GM, Villani RM, Spurdle AB, Turnbull C, CanVIG-UK Consortium. PMID: 40480200; PMCID: PMC12256791.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes. Invest Ophthalmol Vis Sci. 2025 06 02; 66(6):64. Hang A, Shao A, Shea M, Roux MJ, Imai-Leonard DM, Adams DJ, Amano T, Amarie OV, Berberovic Z, Bour R, Bower L, Leonard BC, Brown SD, Cho SY, Clementson-Mobbs S, D'Souza AJ, Dickinson M, Eskandarian M, Flenniken AM, Fuchs H, Gailus-Durner V, Heaney J, Hérault Y, Hrabe de Angelis M, Hsu CW, Jin S, Joynson R, Kang YK, Kim H, Masuya H, Nam KH, Noh H, Nutter LMJ, Palkova M, Prochazka J, Raishbrook MJ, Riet F, Salazar J, Seavitt JR, Sedlacek R, Selloum M, Seo KY, Seong JK, Shin HS, Shiroishi T, Sorg T, Stewart M, Tamura M, Tolentino H, Udensi U, Wells S, Wurst W, Yoshiki A, Meziane H, Yiu G, Sieving PA, Lanoue L, Lloyd KCK, McKerlie C, Moshiri A, International Mouse Phenotyping Consortium (IMPC). PMID: 40548636; PMCID: PMC12186831.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    7. Cyclization of the Analgesic α-Conotoxin Vc1.1 With a Non-Natural Linker: Effects on Structure, Stability, and Bioactivity. J Pept Sci. 2025 Jun; 31(6):e70017. Zhang Y, Tae HS, Adams DJ, Durek T, Craik DJ. PMID: 40256935; PMCID: PMC12010462.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity. Nature. 2025 Apr; 640(8060):1052-1061. Yang J, Yamashita-Kanemaru Y, Morris BI, Contursi A, Trajkovski D, Xu J, Patrascan I, Benson J, Evans AC, Conti AG, Al-Deka A, Dahmani L, Avdic-Belltheus A, Zhang B, Okkenhaug H, Whiteside SK, Imianowski CJ, Wesolowski AJ, Webb LV, Puccio S, Tacconelli S, Bruno A, Di Berardino S, De Michele A, Welch HCE, Yu IS, Lin SW, Mitra S, Lugli E, van der Weyden L, Okkenhaug K, Saeb-Parsy K, Patrignani P, Adams DJ, Roychoudhuri R. PMID: 40044852; PMCID: PMC12018268.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    9. Comprehensive mutational profiling identifies new driver events in cutaneous leiomyosarcoma. Br J Dermatol. 2025 Jan 24; 192(2):335-343. van der Weyden L, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino JM, Offord V, Droop A, Jones DRA, Vermes I, Anderson E, Hardy C, de Saint Aubain N, Ferguson PM, Clarke EL, Merchant W, Mogler C, Frew D, Harms PW, Monteagudo C, Billings SD, Arends MJ, Ferreira I, Brenn T, Adams DJ. PMID: 39392932; PMCID: PMC11758588.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. GABAB Receptor Modulation of Membrane Excitability in Human Pluripotent Stem Cell-Derived Sensory Neurons by Baclofen and α-Conotoxin Vc1.1. J Neurochem. 2025 Jan; 169(1):e70004. St Clair-Glover M, Yousuf A, Kaul D, Dottori M, Adams DJ. PMID: 39871624; PMCID: PMC11773314.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Genomics-informed neuropsychiatric care for neurodevelopmental disorders: Results from a multidisciplinary clinic. Genet Med. 2025 Feb; 27(2):101333. Besterman AD, Adams DJ, Wong NR, Schneider BN, Mehta S, DiStefano C, Wilson RB, Martinez-Agosto JA, Jeste SS. PMID: 39692675.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Discovering EEG biomarkers of Lennox-Gastaut syndrome through unsupervised time-frequency analysis. Epilepsia. 2025 Feb; 66(2):541-553. Hu DK, Pinto-Orellana MA, Rana M, Do L, Adams DJ, Hussain SA, Shrey DW, Lopour BA. PMID: 39666270; PMCID: PMC11827736.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Molecular determinants of the selectivity and potency of α-conotoxin Vc1.1 for human nicotinic acetylcholine receptors. J Biol Chem. 2025 Jan; 301(1):108017. Tae HS, Hung A, Clark RJ, Adams DJ. PMID: 39608712; PMCID: PMC11732461.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    14. Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency. J Exp Med. 2025 01 06; 222(1). Blanco E, Camps C, Bahal S, Kerai MD, Ferla MP, Rochussen AM, Handel AE, Golwala ZM, Spiridou Goncalves H, Kricke S, Klein F, Zhang F, Zinghirino F, Evans G, Keane TM, Lizot S, Kusters MAA, Iro MA, Patel SV, Morris EC, Burns SO, Radcliffe R, Vasudevan P, Price A, Gillham O, Valdebenito GE, Stewart GS, Worth A, Adams SP, Duchen M, André I, Adams DJ, Santili G, Gilmour KC, Holländer GA, Davies EG, Taylor JC, Griffiths GM, Thrasher AJ, Dhalla F, Kreins AY. PMID: 39560673; PMCID: PMC11577440.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    15. Development of an Intravenously Stable Disulfide-Rich Peptide for the Treatment of Chemotherapy-Induced Neuropathic Pain. J Med Chem. 2024 Nov 14; 67(21):18741-18752. Li T, Tae HS, Chen S, Li X, Liang J, Pan T, Zhang Z, Jiang T, Adams DJ, Yu R. PMID: 39448068.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    16. Clinical factors associated with genetic diagnosis in suspected neurogenetic disorders in a tertiary care clinic. Genet Med. 2025 Jan; 27(1):101252. Wong NR, Klomhaus A, Adams DJ, Schneider BN, Mehta S, DiStefano C, Wilson RB, Martinez-Agosto JA, Jeste SS, Besterman AD. PMID: 39395029; PMCID: PMC11717587.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. N-Terminal Capping of the αO-Conotoxin Analogue GeX-2 Improves the Serum Stability and Selectivity toward the Human α9α10 Nicotinic Acetylcholine Receptor. J Med Chem. 2024 Oct 24; 67(20):18400-18411. Li X, Zhou S, Tae HS, Wang S, Li T, Cai W, Jiang T, Adams DJ, Yu R. PMID: 39361522.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    18. Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines. Sci Rep. 2024 09 30; 14(1):22626. Elrick H, Peterson KA, Willis BJ, Lanza DG, Acar EF, Ryder EJ, Teboul L, Kasparek P, Birling MC, Adams DJ, Bradley A, Braun RE, Brown SD, Caulder A, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Duddy G, Gertsenstein M, Goodwin LO, Hérault Y, Lintott LG, Lloyd KCK, Lorenzo I, Mackenzie M, Mallon AM, McKerlie C, Parkinson H, Ramirez-Solis R, Seavitt JR, Sedlacek R, Skarnes WC, Smedley D, Wells S, White JK, Wood JA, International Mouse Phenotyping Consortium, Murray SA, Heaney JD, Nutter LMJ. PMID: 39349521; PMCID: PMC11443006.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    19. Ancestry and somatic profile predict acral melanoma origin and prognosis. medRxiv. 2024 Sep 23. Basurto-Lozada P, Vázquez-Cruz ME, Molina-Aguilar C, Jiang A, Deacon DC, Cerrato-Izaguirre D, Simonin-Wilmer I, Arriaga-González FG, Contreras-Ramírez KL, Dawson ET, Wong-Ramirez JRC, Ramos-Galguera JI, Álvarez-Cano A, García-Ortega DY, García-Salinas OI, Hidalgo-Miranda A, Cisneros-Villanueva M, Martínez-Said H, Arends MJ, Ferreira I, Tullett M, Olvera-León R, van der Weyden L, Del Castillo Velasco Herrera M, Roldán-Marín R, Vidaurri de la Cruz H, Tavares-de-la-Paz LA, Hinojosa-Ugarte D, Belote RL, Bishop DT, Díaz-Gay M, Alexandrov LB, Sánchez-Pérez Y, In GK, White RM, Possik PA, Judson-Torres RL, Adams DJ, Robles-Espinoza CD. PMID: 39399030; PMCID: PMC11469390.
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    20. NUDCD3 deficiency disrupts V(D)J recombination to cause SCID and Omenn syndrome. Sci Immunol. 2024 05 24; 9(95):eade5705. Chen R, Lukianova E, Schim van der Loeff I, Spegarova JS, Willet JDP, James KD, Ryder EJ, Griffin H, IJspeert H, Gajbhiye A, Lamoliatte F, Marin-Rubio JL, Woodbine L, Lemos H, Swan DJ, Pintar V, Sayes K, Ruiz-Morales ER, Eastham S, Dixon D, Prete M, Prigmore E, Jeggo P, Boyes J, Mellor A, Huang L, van der Burg M, Engelhardt KR, Stray-Pedersen A, Erichsen HC, Gennery AR, Trost M, Adams DJ, Anderson G, Lorenc A, Trynka G, Hambleton S. PMID: 38787962.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    21. Tabernanthalog and ibogainalog inhibit the α7 and α9α10 nicotinic acetylcholine receptors via different mechanisms and with higher potency than the GABAA receptor and CaV2.2 channel. Biochem Pharmacol. 2024 05; 223:116183. Tae HS, Ortells MO, Yousuf A, Xu SQ, Akk G, Adams DJ, Arias HR. PMID: 38580167; PMCID: PMC11151864.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    22. Workshop report: the clinical application of data from multiplex assays of variant effect (MAVEs), 12 July 2023. Eur J Hum Genet. 2024 May; 32(5):593-600. Allen S, Garrett A, Muffley L, Fayer S, Foreman J, Adams DJ, Hurles M, Rubin AF, Roth FP, Starita LM, Biesecker LG, Turnbull C. PMID: 38433264; PMCID: PMC11061192.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    23. A gut microbial signature for combination immune checkpoint blockade across cancer types. Nat Med. 2024 Mar; 30(3):797-809. Gunjur A, Shao Y, Rozday T, Klein O, Mu A, Haak BW, Markman B, Kee D, Carlino MS, Underhill C, Frentzas S, Michael M, Gao B, Palmer J, Cebon J, Behren A, Adams DJ, Lawley TD. PMID: 38429524; PMCID: PMC10957475.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    24. Rational Design of Potent α-Conotoxin PeIA Analogues with Non-Natural Amino Acids for the Inhibition of Human α9α10 Nicotinic Acetylcholine Receptors. Mar Drugs. 2024 Feb 27; 22(3). Li T, Tae HS, Liang J, Zhang Z, Li X, Jiang T, Adams DJ, Yu R. PMID: 38535451; PMCID: PMC10971807.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    25. Dual Antagonism of α9α10 nAChR and GABAB Receptor-Coupled CaV2.2 Channels by an Analgesic αO-Conotoxin Analogue. J Med Chem. 2024 01 25; 67(2):971-987. Li X, Tae HS, Chen S, Yousuf A, Huang L, Zhang J, Jiang T, Adams DJ, Yu R. PMID: 38217860.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    26. Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet. Genome Biol. 2024 01 08; 25(1):11. Viner C, Ishak CA, Johnson J, Walker NJ, Shi H, Sjöberg-Herrera MK, Shen SY, Lardo SM, Adams DJ, Ferguson-Smith AC, De Carvalho DD, Hainer SJ, Bailey TL, Hoffman MM. PMID: 38191487; PMCID: PMC10773111.
      View in: PubMed   Mentions: 19     Fields:    
    27. Interrater reliability of interictal EEG waveforms in Lennox-Gastaut Syndrome. Epilepsia Open. 2024 Feb; 9(1):176-186. Hu DK, Rana M, Adams DJ, Do L, Shrey DW, Hussain SA, Lopour BA. PMID: 37920928; PMCID: PMC10839292.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model. Nat Commun. 2023 11 13; 14(1):7295. Fang TZ, Sun Y, Pearce AC, Eleuteri S, Kemp M, Luckhurst CA, Williams R, Mills R, Almond S, Burzynski L, Márkus NM, Lelliott CJ, Karp NA, Adams DJ, Jackson SP, Zhao JF, Ganley IG, Thompson PW, Balmus G, Simon DK. PMID: 37957154; PMCID: PMC10643470.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    29. The role of ion channels in T cell function and disease. Front Immunol. 2023; 14:1238171. Manolios N, Papaemmanouil J, Adams DJ. PMID: 37705981; PMCID: PMC10497217.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    30. Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer. Genome Biol. 2023 08 28; 24(1):191. Wong K, Abascal F, Ludwig L, Aupperle-Lellbach H, Grassinger J, Wright CW, Allison SJ, Pinder E, Phillips RM, Romero LP, Gal A, Roady PJ, Pires I, Guscetti F, Munday JS, Peleteiro MC, Pinto CA, Carvalho T, Cota J, Du Plessis EC, Constantino-Casas F, Plog S, Moe L, de Brot S, Bemelmans I, Amorim RL, Georgy SR, Prada J, Del Pozo J, Heimann M, de Carvalho Nunes L, Simola O, Pazzi P, Steyl J, Ubukata R, Vajdovich P, Priestnall SL, Suárez-Bonnet A, Roperto F, Millanta F, Palmieri C, Ortiz AL, Barros CSL, Gava A, Söderström ME, O'Donnell M, Klopfleisch R, Manrique-Rincón A, Martincorena I, Ferreira I, Arends MJ, Wood GA, Adams DJ, van der Weyden L. PMID: 37635261; PMCID: PMC10464500.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    31. A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3. PLoS Biol. 2023 08; 21(8):e3002217. Hackney CM, Flórez Salcedo P, Mueller E, Koch TL, Kjelgaard LD, Watkins M, Zachariassen LG, Tuelung PS, McArthur JR, Adams DJ, Kristensen AS, Olivera B, Finol-Urdaneta RK, Safavi-Hemami H, Morth JP, Ellgaard L. PMID: 37535677; PMCID: PMC10437998.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    32. Brevetoxin versus Brevenal Modulation of Human Nav1 Channels. Mar Drugs. 2023 Jul 07; 21(7). Finol-Urdaneta RK, Zhorov BS, Baden DG, Adams DJ. PMID: 37504927; PMCID: PMC10382042.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    33. An Atlas of Variant Effects to understand the genome at nucleotide resolution. Genome Biol. 2023 07 03; 24(1):147. Fowler DM, Adams DJ, Gloyn AL, Hahn WC, Marks DS, Muffley LA, Neal JT, Roth FP, Rubin AF, Starita LM, Hurles ME. PMID: 37394429; PMCID: PMC10316620.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    34. DM506 (3-Methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole fumarate), a Novel Derivative of Ibogamine, Inhibits α7 and α9α10 Nicotinic Acetylcholine Receptors by Different Allosteric Mechanisms. ACS Chem Neurosci. 2023 07 19; 14(14):2537-2547. Tae HS, Ortells MO, Tekarli BJ, Manetti D, Romanelli MN, McIntosh JM, Adams DJ, Arias HR. PMID: 37386821.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    35. Automated Patch Clamp Screening of Amiloride and 5-N,N-Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor. Mol Pharm. 2023 07 03; 20(7):3367-3379. Finol-Urdaneta RK, McArthur JR, Aboelela A, Bujaroski RS, Majed H, Rangel A, Adams DJ, Ranson M, Kelso MJ, Buckley BJ. PMID: 37260417.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    36. Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules. ACS Cent Sci. 2023 May 24; 9(5):892-904. Mikutis S, Rebelo M, Yankova E, Gu M, Tang C, Coelho AR, Yang M, Hazemi ME, Pires de Miranda M, Eleftheriou M, Robertson M, Vassiliou GS, Adams DJ, Simas JP, Corzana F, Schneekloth JS, Tzelepis K, Bernardes GJL. PMID: 37252343; PMCID: PMC10214512.
      View in: PubMed   Mentions: 23  
    37. The Antinociceptive Activity of (E)-3-(thiophen-2-yl)- N -(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)- N -methyl- N -(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor. Anesth Analg. 2023 09 01; 137(3):691-701. Arias HR, Tae HS, Micheli L, Yousuf A, Manetti D, Romanelli MN, Ghelardini C, Adams DJ, Di Cesare Mannelli L. PMID: 37058425; PMCID: PMC10408732.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    38. Nicotinic acetylcholine receptor subtype expression, function, and pharmacology: Therapeutic potential of α-conotoxins. Pharmacol Res. 2023 05; 191:106747. Tae HS, Adams DJ. PMID: 37001708.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    39. Nicotinic acetylcholine receptors: Key targets for attenuating neurodegenerative diseases. Int J Biochem Cell Biol. 2023 04; 157:106387. Bye LJ, Finol-Urdaneta RK, Tae HS, Adams DJ. PMID: 36754161.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    40. Genome-wide screening reveals the genetic basis of mammalian embryonic eye development. BMC Biol. 2023 02 03; 21(1):22. Chee JM, Lanoue L, Clary D, Higgins K, Bower L, Flenniken A, Guo R, Adams DJ, Bosch F, Braun RE, Brown SDM, Chin HG, Dickinson ME, Hsu CW, Dobbie M, Gao X, Galande S, Grobler A, Heaney JD, Herault Y, de Angelis MH, Mammano F, Nutter LMJ, Parkinson H, Qin C, Shiroishi T, Sedlacek R, Seong JK, Xu Y, International Mouse Phenotyping Consortium, Brooks B, McKerlie C, Lloyd KCK, Westerberg H, Moshiri A. PMID: 36737727; PMCID: PMC9898963.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    41. Association of germline variants in telomere maintenance genes (POT1, TERF2IP, ACD, and TERT) with spitzoid morphology in familial melanoma: A multi-center case series. JAAD Int. 2023 Jun; 11:43-51. Goldstein AM, Qin R, Chu EY, Elder DE, Massi D, Adams DJ, Harms PW, Robles-Espinoza CD, Newton-Bishop JA, Bishop DT, Harland M, Holland EA, Cust AE, Schmid H, Mann GJ, Puig S, Potrony M, Alos L, Nagore E, Millán-Esteban D, Hayward NK, Broit N, Palmer JM, Nathan V, Berry EG, Astiazaran-Symonds E, Yang XR, Tucker MA, Landi MT, Pfeiffer RM, Sargen MR. PMID: 36876055; PMCID: PMC9978843.
      View in: PubMed   Mentions: 8  
    42. Advances in Xanthan Gum-Based Systems for the Delivery of Therapeutic Agents. Pharmaceutics. 2023 Jan 25; 15(2). Jadav M, Pooja D, Adams DJ, Kulhari H. PMID: 36839724; PMCID: PMC9967536.
      View in: PubMed   Mentions: 26  
    43. Characterisation of Elevenin-Vc1 from the Venom of Conus victoriae: A Structural Analogue of α-Conotoxins. Mar Drugs. 2023 Jan 25; 21(2). Krishnarjuna B, Sunanda P, Seow J, Tae HS, Robinson SD, Belgi A, Robinson AJ, Safavi-Hemami H, Adams DJ, Norton RS. PMID: 36827123; PMCID: PMC9963005.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    44. Calcium Imaging of Non-adherent Cells. Methods Mol Biol. 2023; 2644:361-369. Bye LJ, Finol-Urdaneta RK, Adams DJ. PMID: 37142934.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    45. Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes. Sci Rep. 2022 12 01; 12(1):20791. Higgins K, Moore BA, Berberovic Z, Adissu HA, Eskandarian M, Flenniken AM, Shao A, Imai DM, Clary D, Lanoue L, Newbigging S, Nutter LMJ, Adams DJ, Bosch F, Braun RE, Brown SDM, Dickinson ME, Dobbie M, Flicek P, Gao X, Galande S, Grobler A, Heaney JD, Herault Y, de Angelis MH, Chin HG, Mammano F, Qin C, Shiroishi T, Sedlacek R, Seong JK, Xu Y, IMPC Consortium, Lloyd KCK, McKerlie C, Moshiri A. PMID: 36456625; PMCID: PMC9715561.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    46. Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis. Cancer Res. 2022 11 15; 82(22):4261-4273. Vaishnavi A, Juan J, Jacob M, Stehn C, Gardner EE, Scherzer MT, Schuman S, Van Veen JE, Murphy B, Hackett CS, Dupuy AJ, Chmura SA, van der Weyden L, Newberg JY, Liu A, Mann K, Rust AG, Weiss WA, Kinsey CG, Adams DJ, Grossmann A, Mann MB, McMahon M. PMID: 36112789; PMCID: PMC9664136.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    47. Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor. Cell Genom. 2022 Nov 09; 2(11):None. Islam SMA, Díaz-Gay M, Wu Y, Barnes M, Vangara R, Bergstrom EN, He Y, Vella M, Wang J, Teague JW, Clapham P, Moody S, Senkin S, Li YR, Riva L, Zhang T, Gruber AJ, Steele CD, Otlu B, Khandekar A, Abbasi A, Humphreys L, Syulyukina N, Brady SW, Alexandrov BS, Pillay N, Zhang J, Adams DJ, Martincorena I, Wedge DC, Landi MT, Brennan P, Stratton MR, Rozen SG, Alexandrov LB. PMID: 36388765; PMCID: PMC9646490.
      View in: PubMed   Mentions: 182     Fields:    
    48. HIRA loss transforms FH-deficient cells. Sci Adv. 2022 Oct 21; 8(42):eabq8297. Valcarcel-Jimenez L, Rogerson C, Yong C, Schmidt C, Yang M, Cremades-Rodelgo M, Harle V, Offord V, Wong K, Mora A, Speed A, Caraffini V, Tran MGB, Maher ER, Stewart GD, Vanharanta S, Adams DJ, Frezza C. PMID: 36269833; PMCID: PMC9586478.
      View in: PubMed   Mentions: 9     Fields:    
    49. Mechanism of Action and Structure-Activity Relationship of α-Conotoxin Mr1.1 at the Human α9α10 Nicotinic Acetylcholine Receptor. J Med Chem. 2022 12 22; 65(24):16204-16217. Liang J, Tae HS, Zhao Z, Li X, Zhang J, Chen S, Jiang T, Adams DJ, Yu R. PMID: 36137181.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    50. Analgesic α-Conotoxin Binding Site on the Human GABAB Receptor. Mol Pharmacol. 2022 10; 102(4):196-208. Bony AR, McArthur JR, Komori A, Wong AR, Hung A, Adams DJ. PMID: 35944919.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    51. Single-Disulfide Conopeptide Czon1107, an Allosteric Antagonist of the Human α3β4 Nicotinic Acetylcholine Receptor. Mar Drugs. 2022 Jul 31; 20(8). Ma Y, Cao Q, Yang M, Gao Y, Fu S, Du W, Adams DJ, Jiang T, Tae HS, Yu R. PMID: 36005500; PMCID: PMC9409646.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. µ-Theraphotoxin Pn3a inhibition of CaV3.3 channels reveals a novel isoform-selective drug binding site. Elife. 2022 07 20; 11. McArthur JR, Wen J, Hung A, Finol-Urdaneta RK, Adams DJ. PMID: 35858123; PMCID: PMC9342953.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    53. Investigation of CACNA1I Cav3.3 Dysfunction in Hemiplegic Migraine. Front Mol Neurosci. 2022; 15:892820. Maksemous N, Blayney CD, Sutherland HG, Smith RA, Lea RA, Tran KN, Ibrahim O, McArthur JR, Haupt LM, Cader MZ, Finol-Urdaneta RK, Adams DJ, Griffiths LR. PMID: 35928792; PMCID: PMC9345121.
      View in: PubMed   Mentions: 12  
    54. SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination. Nat Commun. 2022 06 28; 13(1):3707. Vincendeau E, Wei W, Zhang X, Planchais C, Yu W, Lenden-Hasse H, Cokelaer T, Pipoli da Fonseca J, Mouquet H, Adams DJ, Alt FW, Jackson SP, Balmus G, Lescale C, Deriano L. PMID: 35764636; PMCID: PMC9240092.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    55. Glycinergic Modulation of Pain in Behavioral Animal Models. Front Pharmacol. 2022; 13:860903. Peiser-Oliver JM, Evans S, Adams DJ, Christie MJ, Vandenberg RJ, Mohammadi SA. PMID: 35694265; PMCID: PMC9174897.
      View in: PubMed   Mentions: 4  
    56. Author Correction: Tumour gene expression signature in primary melanoma predicts long-term outcomes. Nat Commun. 2022 May 17; 13(1):2841. Garg M, Couturier DL, Nsengimana J, Fonseca NA, Wongchenko M, Yan Y, Lauss M, Jönsson GB, Newton-Bishop J, Parkinson C, Middleton MR, Bishop DT, McDonald S, Stefanos N, Tadross J, Vergara IA, Lo S, Newell F, Wilmott JS, Thompson JF, Long GV, Scolyer RA, Corrie P, Adams DJ, Brazma A, Rabbie R. PMID: 35581257; PMCID: PMC9114317.
      View in: PubMed   Mentions: 1     Fields:    
    57. A 4/8 Subtype α-Conotoxin Vt1.27 Inhibits N-Type Calcium Channels With Potent Anti-Allodynic Effect. Front Pharmacol. 2022; 13:881732. Wang S, Bartels P, Zhao C, Yousuf A, Liu Z, Yu S, Bony AR, Ma X, Dai Q, Sun T, Liu N, Yang M, Yu R, Du W, Adams DJ, Dai Q. PMID: 35754473; PMCID: PMC9230573.
      View in: PubMed   Mentions: 1  
    58. Germline MBD4 deficiency causes a multi-tumor predisposition syndrome. Am J Hum Genet. 2022 05 05; 109(5):953-960. Palles C, West HD, Chew E, Galavotti S, Flensburg C, Grolleman JE, Jansen EAM, Curley H, Chegwidden L, Arbe-Barnes EH, Lander N, Truscott R, Pagan J, Bajel A, Sherwood K, Martin L, Thomas H, Georgiou D, Fostira F, Goldberg Y, Adams DJ, van der Biezen SAM, Christie M, Clendenning M, Thomas LE, Deltas C, Dimovski AJ, Dymerska D, Lubinski J, Mahmood K, van der Post RS, Sanders M, Weitz J, Taylor JC, Turnbull C, Vreede L, van Wezel T, Whalley C, Arnedo-Pac C, Caravagna G, Cross W, Chubb D, Frangou A, Gruber AJ, Kinnersley B, Noyvert B, Church D, Graham T, Houlston R, Lopez-Bigas N, Sottoriva A, Wedge D, Genomics England Research Consortium, CORGI Consortium, WGS500 Consortium, Jenkins MA, Kuiper RP, Roberts AW, Cheadle JP, Ligtenberg MJL, Hoogerbrugge N, Koelzer VH, Rivas AD, Winship IM, Ponte CR, Buchanan DD, Power DG, Green A, Tomlinson IPM, Sampson JR, Majewski IJ, de Voer RM. PMID: 35460607; PMCID: PMC9118112.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    59. CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia. Blood. 2022 04 07; 139(14):2227-2239. Bennett C, Lawrence M, Guerrero JA, Stritt S, Waller AK, Yan Y, Mifsud RW, Ballester-Beltrán J, Baig A, Mueller A, Mayer L, Warland J, Penkett CJ, Akbari P, Moreau T, Evans AL, Mookerjee S, Hoffman GJ, Saeb-Parsy K, Adams DJ, Couzens AL, Bender M, Erber WN, Nieswandt B, Read RJ, Ghevaert C. PMID: 35051265; PMCID: PMC7614665.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    60. Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis. Nat Microbiol. 2022 04; 7(4):590-599. Forster SC, Clare S, Beresford-Jones BS, Harcourt K, Notley G, Stares MD, Kumar N, Soderholm AT, Adoum A, Wong H, Morón B, Brandt C, Dougan G, Adams DJ, Maloy KJ, Pedicord VA, Lawley TD. PMID: 35365791; PMCID: PMC8975739.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    61. Cysteine-Rich α-Conotoxin SII Displays Novel Interactions at the Muscle Nicotinic Acetylcholine Receptor. ACS Chem Neurosci. 2022 04 20; 13(8):1245-1250. Wilhelm P, Luna-Ramirez K, Chin YK, Dekan Z, Abraham N, Tae HS, Chow CY, Eagles DA, King GF, Lewis RJ, Adams DJ, Alewood PF. PMID: 35357806.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    62. Editorial: Sensory Abnormalities and Primary Sensory Neurons. Front Cell Neurosci. 2022; 16:852614. Masuoka T, Acosta MC, Adams DJ. PMID: 35185476; PMCID: PMC8854170.
      View in: PubMed   Mentions:
    63. Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider. Proc Natl Acad Sci U S A. 2022 02 01; 119(5). Finol-Urdaneta RK, Ziegman R, Dekan Z, McArthur JR, Heitmann S, Luna-Ramirez K, Tae HS, Mueller A, Starobova H, Chin YK, Wingerd JS, Undheim EAB, Cristofori-Armstrong B, Hill AP, Herzig V, King GF, Vetter I, Rash LD, Adams DJ, Alewood PF. PMID: 35074873; PMCID: PMC8812547.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    64. Ulcerated melanoma: Systems biology evidence of inflammatory imbalance towards pro-tumourigenicity. Pigment Cell Melanoma Res. 2022 03; 35(2):252-267. Davies J, Muralidhar S, Randerson-Moor J, Harland M, O'Shea S, Diaz J, Walker C, Nsengimana J, Laye J, Mell T, Chan M, Appleton L, Birkeälv S, Adams DJ, Cook GP, Ball G, Bishop DT, Newton-Bishop JA. PMID: 34826184.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    65. Analgesic α-conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABAB receptors and reduce neuroexcitability. Br J Pharmacol. 2022 01; 179(1):179-198. Bony AR, McArthur JR, Finol-Urdaneta RK, Adams DJ. PMID: 34599513.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    66. ɑO-Conotoxin GeXIVA isomers modulate N-type calcium (CaV 2.2) channels and inwardly-rectifying potassium (GIRK) channels via GABAB receptor activation. J Neurochem. 2022 01; 160(2):154-171. Yousuf A, Wu X, Bony AR, Sadeghi M, Huang YH, Craik DJ, Adams DJ. PMID: 34738241.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    67. Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma. J Clin Invest. 2021 10 15; 131(20). Peri A, Greenstein E, Alon M, Pai JA, Dingjan T, Reich-Zeliger S, Barnea E, Barbolin C, Levy R, Arnedo-Pac C, Kalaora S, Dassa B, Feldmesser E, Shang P, Greenberg P, Levin Y, Benedek G, Levesque MP, Adams DJ, Lotem M, Wilmott JS, Scolyer RA, Jönsson GB, Admon A, Rosenberg SA, Cohen CJ, Niv MY, Lopez-Bigas N, Satpathy AT, Friedman N, Samuels Y. PMID: 34651586; PMCID: PMC8516471.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    68. Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation. Dev Cell. 2021 10 25; 56(20):2808-2825.e10. Campbell NR, Rao A, Hunter MV, Sznurkowska MK, Briker L, Zhang M, Baron M, Heilmann S, Deforet M, Kenny C, Ferretti LP, Huang TH, Perlee S, Garg M, Nsengimana J, Saini M, Montal E, Tagore M, Newton-Bishop J, Middleton MR, Corrie P, Adams DJ, Rabbie R, Aceto N, Levesque MP, Cornell RA, Yanai I, Xavier JB, White RM. PMID: 34529939; PMCID: PMC8551056.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    69. Electrical properties and synaptic transmission in mouse intracardiac ganglion neurons in situ. Physiol Rep. 2021 09; 9(18):e15056. Harper AA, Adams DJ. PMID: 34582125; PMCID: PMC8477906.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    70. Hi-C scaffolded short- and long-read genome assemblies of the California sea lion are broadly consistent for syntenic inference across 45 million years of evolution. Mol Ecol Resour. 2021 Oct; 21(7):2455-2470. Peart CR, Williams C, Pophaly SD, Neely BA, Gulland FMD, Adams DJ, Ng BL, Cheng W, Goebel ME, Fedrigo O, Haase B, Mountcastle J, Fungtammasan A, Formenti G, Collins J, Wood J, Sims Y, Torrance J, Tracey A, Howe K, Rhie A, Hoffman JI, Johnson J, Jarvis ED, Breen M, Wolf JBW. PMID: 34097816; PMCID: PMC9732816.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    71. α-Conotoxin Bt1.8 from Conus betulinus selectively inhibits α6/α3β2β3 and α3β2 nicotinic acetylcholine receptor subtypes. J Neurochem. 2021 10; 159(1):90-100. Ning H, Huang B, Tae HS, Liu Z, Yu S, Li L, Zhang L, Adams DJ, Guo C, Dai Q. PMID: 34008858.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    72. The clinicopathologic spectrum and genomic landscape of de-/trans-differentiated melanoma. Mod Pathol. 2021 11; 34(11):2009-2019. Ferreira I, Droop A, Edwards O, Wong K, Harle V, Habeeb O, Gharpuray-Pandit D, Houghton J, Wiedemeyer K, Mentzel T, Billings SD, Ko JS, Füzesi L, Mulholland K, Prusac IK, Liegl-Atzwanger B, de Saint Aubain N, Caldwell H, Riva L, van der Weyden L, Arends MJ, Brenn T, Adams DJ. PMID: 34155350.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    73. Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors. Biochem Pharmacol. 2021 08; 190:114638. Tae HS, Gao B, Jin AH, Alewood PF, Adams DJ. PMID: 34062129.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    74. Publisher Correction: Accelerating functional gene discovery in osteoarthritis. Nat Commun. 2021 May 28; 12(1):3302. Butterfield NC, Curry KF, Steinberg J, Dewhurst H, Komla-Ebri D, Mannan NS, Adoum AT, Leitch VD, Logan JG, Waung JA, Ghirardello E, Southam L, Youlten SE, Wilkinson JM, McAninch EA, Vancollie VE, Kussy F, White JK, Lelliott CJ, Adams DJ, Jacques R, Bianco AC, Boyde A, Zeggini E, Croucher PI, Williams GR, Bassett JHD. PMID: 34050183; PMCID: PMC8163861.
      View in: PubMed   Mentions: 3     Fields:    
    75. Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease. Nat Commun. 2021 05 05; 12(1):2444. Youlten SE, Kemp JP, Logan JG, Ghirardello EJ, Sergio CM, Dack MRG, Guilfoyle SE, Leitch VD, Butterfield NC, Komla-Ebri D, Chai RC, Corr AP, Smith JT, Mohanty ST, Morris JA, McDonald MM, Quinn JMW, McGlade AR, Bartonicek N, Jansson M, Hatzikotoulas K, Irving MD, Beleza-Meireles A, Rivadeneira F, Duncan E, Richards JB, Adams DJ, Lelliott CJ, Brink R, Phan TG, Eisman JA, Evans DM, Zeggini E, Baldock PA, Bassett JHD, Williams GR, Croucher PI. PMID: 33953184; PMCID: PMC8100170.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    76. Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes. Cell. 2021 04 15; 184(8):2239-2254.e39. Dentro SC, Leshchiner I, Haase K, Tarabichi M, Wintersinger J, Deshwar AG, Yu K, Rubanova Y, Macintyre G, Demeulemeester J, Vázquez-García I, Kleinheinz K, Livitz DG, Malikic S, Donmez N, Sengupta S, Anur P, Jolly C, Cmero M, Rosebrock D, Schumacher SE, Fan Y, Fittall M, Drews RM, Yao X, Watkins TBK, Lee J, Schlesner M, Zhu H, Adams DJ, McGranahan N, Swanton C, Getz G, Boutros PC, Imielinski M, Beroukhim R, Sahinalp SC, Ji Y, Peifer M, Martincorena I, Markowetz F, Mustonen V, Yuan K, Gerstung M, Spellman PT, Wang W, Morris QD, Wedge DC, Van Loo P, PCAWG Evolution and Heterogeneity Working Group and the PCAWG Consortium. PMID: 33831375; PMCID: PMC8054914.
      View in: PubMed   Mentions: 270     Fields:    Translation:Humans
    77. A resource of targeted mutant mouse lines for 5,061 genes. Nat Genet. 2021 04; 53(4):416-419. Birling MC, Yoshiki A, Adams DJ, Ayabe S, Beaudet AL, Bottomley J, Bradley A, Brown SDM, Bürger A, Bushell W, Chiani F, Chin HG, Christou S, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Donahue LR, Fray MD, Gambadoro A, Gao X, Gertsenstein M, Gomez-Segura A, Goodwin LO, Heaney JD, Hérault Y, de Angelis MH, Jiang ST, Justice MJ, Kasparek P, King RE, Kühn R, Lee H, Lee YJ, Liu Z, Lloyd KCK, Lorenzo I, Mallon AM, McKerlie C, Meehan TF, Fuentes VM, Newman S, Nutter LMJ, Oh GT, Pavlovic G, Ramirez-Solis R, Rosen B, Ryder EJ, Santos LA, Schick J, Seavitt JR, Sedlacek R, Seisenberger C, Seong JK, Skarnes WC, Sorg T, Steel KP, Tamura M, Tocchini-Valentini GP, Wang CL, Wardle-Jones H, Wattenhofer-Donzé M, Wells S, Wiles MV, Willis BJ, Wood JA, Wurst W, Xu Y, International Mouse Phenotyping Consortium (IMPC), Teboul L, Murray SA. PMID: 33833456; PMCID: PMC8397259.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    78. Identification of bacteria-derived HLA-bound peptides in melanoma. Nature. 2021 04; 592(7852):138-143. Kalaora S, Nagler A, Nejman D, Alon M, Barbolin C, Barnea E, Ketelaars SLC, Cheng K, Vervier K, Shental N, Bussi Y, Rotkopf R, Levy R, Benedek G, Trabish S, Dadosh T, Levin-Zaidman S, Geller LT, Wang K, Greenberg P, Yagel G, Peri A, Fuks G, Bhardwaj N, Reuben A, Hermida L, Johnson SB, Galloway-Peña JR, Shropshire WC, Bernatchez C, Haymaker C, Arora R, Roitman L, Eilam R, Weinberger A, Lotan-Pompan M, Lotem M, Admon A, Levin Y, Lawley TD, Adams DJ, Levesque MP, Besser MJ, Schachter J, Golani O, Segal E, Geva-Zatorsky N, Ruppin E, Kvistborg P, Peterson SN, Wargo JA, Straussman R, Samuels Y. PMID: 33731925; PMCID: PMC9717498.
      View in: PubMed   Mentions: 208     Fields:    Translation:HumansCells
    79. Alkyne-Bridged α-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models. J Med Chem. 2021 03 25; 64(6):3222-3233. Belgi A, Burnley JV, MacRaild CA, Chhabra S, Elnahriry KA, Robinson SD, Gooding SG, Tae HS, Bartels P, Sadeghi M, Zhao FY, Wei H, Spanswick D, Adams DJ, Norton RS, Robinson AJ. PMID: 33724033.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    80. Tumour gene expression signature in primary melanoma predicts long-term outcomes. Nat Commun. 2021 02 18; 12(1):1137. Garg M, Couturier DL, Nsengimana J, Fonseca NA, Wongchenko M, Yan Y, Lauss M, Jönsson GB, Newton-Bishop J, Parkinson C, Middleton MR, Bishop DT, McDonald S, Stefanos N, Tadross J, Vergara IA, Lo S, Newell F, Wilmott JS, Thompson JF, Long GV, Scolyer RA, Corrie P, Adams DJ, Brazma A, Rabbie R. PMID: 33602918; PMCID: PMC7893180.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    81. Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses. Sci Transl Med. 2021 02 17; 13(581). Lo JA, Kawakubo M, Juneja VR, Su MY, Erlich TH, LaFleur MW, Kemeny LV, Rashid M, Malehmir M, Rabi SA, Raghavan R, Allouche J, Kasumova G, Frederick DT, Pauken KE, Weng QY, Pereira da Silva M, Xu Y, van der Sande AAJ, Silkworth W, Roider E, Browne EP, Lieb DJ, Wang B, Garraway LA, Wu CJ, Flaherty KT, Brinckerhoff CE, Mullins DW, Adams DJ, Hacohen N, Hoang MP, Boland GM, Freeman GJ, Sharpe AH, Manstein D, Fisher DE. PMID: 33597266; PMCID: PMC8130008.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    82. Trends in peptide drug discovery. Nat Rev Drug Discov. 2021 04; 20(4):309-325. Muttenthaler M, King GF, Adams DJ, Alewood PF. PMID: 33536635.
      View in: PubMed   Mentions: 595     Fields:    Translation:HumansAnimalsCells
    83. Spider Venom Peptide Pn3a Inhibition of Primary Afferent High Voltage-Activated Calcium Channels. Front Pharmacol. 2020; 11:633679. McArthur JR, Munasinghe NR, Finol-Urdaneta RK, Adams DJ, Christie MJ. PMID: 33584315; PMCID: PMC7875911.
      View in: PubMed   Mentions: 3  
    84. Accelerating functional gene discovery in osteoarthritis. Nat Commun. 2021 01 20; 12(1):467. Butterfield NC, Curry KF, Steinberg J, Dewhurst H, Komla-Ebri D, Mannan NS, Adoum AT, Leitch VD, Logan JG, Waung JA, Ghirardello E, Southam L, Youlten SE, Wilkinson JM, McAninch EA, Vancollie VE, Kussy F, White JK, Lelliott CJ, Adams DJ, Jacques R, Bianco AC, Boyde A, Zeggini E, Croucher PI, Williams GR, Bassett JHD. PMID: 33473114; PMCID: PMC7817695.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    85. Venom-Derived Peptides Inhibiting Voltage-Gated Sodium and Calcium Channels in Mammalian Sensory Neurons. Adv Exp Med Biol. 2021; 1349:3-19. Yousuf A, Sadeghi M, Adams DJ. PMID: 35138607.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    86. Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor. Pharmacol Ther. 2021 06; 222:107792. Li X, Tae HS, Chu Y, Jiang T, Adams DJ, Yu R. PMID: 33309557.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    87. Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons. Front Cell Neurosci. 2020; 14:600895. Hulme AJ, McArthur JR, Maksour S, Miellet S, Ooi L, Adams DJ, Finol-Urdaneta RK, Dottori M. PMID: 33362470; PMCID: PMC7761588.
      View in: PubMed   Mentions: 16  
    88. (E)-3-Furan-2-yl-N-p-tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation. ACS Chem Neurosci. 2020 11 04; 11(21):3603-3614. Arias HR, Ghelardini C, Lucarini E, Tae HS, Yousuf A, Marcovich I, Manetti D, Romanelli MN, Elgoyhen AB, Adams DJ, Di Cesare Mannelli L. PMID: 33073974.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    89. The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence. Br J Cancer. 2021 01; 124(1):156-160. Rabbie R, Ferguson P, Wong K, Couturier DL, Moran U, Turner C, Emanuel P, Haas K, Saunus JM, Davidson MR, Lakhani SR, Shivalingam B, Long GV, Parkinson C, Osman I, Scolyer RA, Corrie P, Adams DJ. PMID: 33024263; PMCID: PMC7782512.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    90. Rational Design of α-Conotoxin RegIIA Analogues Selectively Inhibiting the Human α3β2 Nicotinic Acetylcholine Receptor through Computational Scanning. ACS Chem Neurosci. 2020 09 16; 11(18):2804-2811. Xu Q, Tae HS, Wang Z, Jiang T, Adams DJ, Yu R. PMID: 32649832.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    91. A method for high-content functional imaging of intracellular calcium responses in gelatin-immobilized non-adherent cells. Exp Cell Res. 2020 10 15; 395(2):112210. Ritter P, Bye LJ, Finol-Urdaneta RK, Lesko C, Adams DJ, Friedrich O, Gilbert DF. PMID: 32750330.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    92. N-acetyl-d-glucosamine-conjugated PAMAM dendrimers as dual receptor-targeting nanocarriers for anticancer drug delivery. Eur J Pharm Biopharm. 2020 Sep; 154:377-386. Pooja D, Srinivasa Reddy T, Kulhari H, Kadari A, Adams DJ, Bansal V, Sistla R. PMID: 32717387.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    93. Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy. Nat Commun. 2020 07 23; 11(1):3698. Lee YR, Khan K, Armfield-Uhas K, Srikanth S, Thompson NA, Pardo M, Yu L, Norris JW, Peng Y, Gripp KW, Aleck KA, Li C, Spence E, Choi TI, Kwon SJ, Park HM, Yu D, Heo WD, Mooney MR, Baig SM, Wentzensen IM, Telegrafi A, McWalter K, Moreland T, Roadhouse C, Ramsey K, Lyons MJ, Skinner C, Alexov E, Katsanis N, Stevenson RE, Choudhary JS, Adams DJ, Kim CH, Davis EE, Schwartz CE. PMID: 32703943; PMCID: PMC7378245.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    94. Interactions of the α3β2 Nicotinic Acetylcholine Receptor Interfaces with α-Conotoxin LsIA and its Carboxylated C-terminus Analogue: Molecular Dynamics Simulations. Mar Drugs. 2020 Jul 03; 18(7). Wen J, Adams DJ, Hung A. PMID: 32635340; PMCID: PMC7401271.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    95. Coronaridine congeners decrease neuropathic pain in mice and inhibit α9α10 nicotinic acetylcholine receptors and CaV2.2 channels. Neuropharmacology. 2020 09 15; 175:108194. Arias HR, Tae HS, Micheli L, Yousuf A, Ghelardini C, Adams DJ, Di Cesare Mannelli L. PMID: 32540451.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    96. Dimerization of α-Conotoxins as a Strategy to Enhance the Inhibition of the Human α7 and α9α10 Nicotinic Acetylcholine Receptors. J Med Chem. 2020 03 26; 63(6):2974-2985. Liang J, Tae HS, Xu X, Jiang T, Adams DJ, Yu R. PMID: 32101438.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    97. Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors. Br J Pharmacol. 2020 04; 177(8):1822-1840. Foo CS, Jobichen C, Hassan-Puttaswamy V, Dekan Z, Tae HS, Bertrand D, Adams DJ, Alewood PF, Sivaraman J, Nirthanan S, Kini RM. PMID: 31877243; PMCID: PMC7070178.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    98. The Deep Genome Project. Genome Biol. 2020 02 03; 21(1):18. Lloyd KCK, Adams DJ, Baynam G, Beaudet AL, Bosch F, Boycott KM, Braun RE, Caulfield M, Cohn R, Dickinson ME, Dobbie MS, Flenniken AM, Flicek P, Galande S, Gao X, Grobler A, Heaney JD, Herault Y, de Angelis MH, Lupski JR, Lyonnet S, Mallon AM, Mammano F, MacRae CA, McInnes R, McKerlie C, Meehan TF, Murray SA, Nutter LMJ, Obata Y, Parkinson H, Pepper MS, Sedlacek R, Seong JK, Shiroishi T, Smedley D, Tocchini-Valentini G, Valle D, Wang CL, Wells S, White J, Wurst W, Xu Y, Brown SDM. PMID: 32008577; PMCID: PMC6996159.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    99. Human and mouse essentiality screens as a resource for disease gene discovery. Nat Commun. 2020 01 31; 11(1):655. Cacheiro P, Muñoz-Fuentes V, Murray SA, Dickinson ME, Bucan M, Nutter LMJ, Peterson KA, Haselimashhadi H, Flenniken AM, Morgan H, Westerberg H, Konopka T, Hsu CW, Christiansen A, Lanza DG, Beaudet AL, Heaney JD, Fuchs H, Gailus-Durner V, Sorg T, Prochazka J, Novosadova V, Lelliott CJ, Wardle-Jones H, Wells S, Teboul L, Cater H, Stewart M, Hough T, Wurst W, Sedlacek R, Adams DJ, Seavitt JR, Tocchini-Valentini G, Mammano F, Braun RE, McKerlie C, Herault Y, de Angelis MH, Mallon AM, Lloyd KCK, Brown SDM, Parkinson H, Meehan TF, Smedley D, Genomics England Research Consortium, International Mouse Phenotyping Consortium. PMID: 32005800; PMCID: PMC6994715.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimals
    100. Ketamine inhibits synaptic transmission and nicotinic acetylcholine receptor-mediated responses in rat intracardiac ganglia in situ. Neuropharmacology. 2020 03 15; 165:107932. Harper AA, Rimmer K, Dyavanapalli J, McArthur JR, Adams DJ. PMID: 31911104.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    101. Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom. Biochem Pharmacol. 2020 04; 174:113782. Luna-Ramirez K, Csoti A, McArthur JR, Chin YKY, Anangi R, Najera RDC, Possani LD, King GF, Panyi G, Yu H, Adams DJ, Finol-Urdaneta RK. PMID: 31881193.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    102. High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation. Nat Immunol. 2020 01; 21(1):86-100. Abeler-Dörner L, Laing AG, Lorenc A, Ushakov DS, Clare S, Speak AO, Duque-Correa MA, White JK, Ramirez-Solis R, Saran N, Bull KR, Morón B, Iwasaki J, Barton PR, Caetano S, Hng KI, Cambridge E, Forman S, Crockford TL, Griffiths M, Kane L, Harcourt K, Brandt C, Notley G, Babalola KO, Warren J, Mason JC, Meeniga A, Karp NA, Melvin D, Cawthorne E, Weinrick B, Rahim A, Drissler S, Meskas J, Yue A, Lux M, Song-Zhao GX, Chan A, Ballesteros Reviriego C, Abeler J, Wilson H, Przemska-Kosicka A, Edmans M, Strevens N, Pasztorek M, Meehan TF, Powrie F, Brinkman R, Dougan G, Jacobs W, Lloyd CM, Cornall RJ, Maloy KJ, Grencis RK, Griffiths GM, Adams DJ, Hayday AC. PMID: 31844327; PMCID: PMC7338221.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    103. On-resin strategy to label α-conotoxins: Cy5-RgIA, a potent α9α10 nicotinic acetylcholine receptor imaging probe. Aust J Chem. 2020; 73(4):327-333. Muttenthaler M, Nevin ST, Inserra M, Lewis RJ, Adams DJ, Alewood P. PMID: 32394983; PMCID: PMC7212043.
      View in: PubMed   Mentions: 4  
    104. Vitamin D-VDR Signaling Inhibits Wnt/β-Catenin-Mediated Melanoma Progression and Promotes Antitumor Immunity. Cancer Res. 2019 12 01; 79(23):5986-5998. Muralidhar S, Filia A, Nsengimana J, Pozniak J, O'Shea SJ, Diaz JM, Harland M, Randerson-Moor JA, Reichrath J, Laye JP, van der Weyden L, Adams DJ, Bishop DT, Newton-Bishop J. PMID: 31690667.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    105. Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis. Cancer Cell. 2019 09 16; 36(3):319-336.e7. Jackstadt R, van Hooff SR, Leach JD, Cortes-Lavaud X, Lohuis JO, Ridgway RA, Wouters VM, Roper J, Kendall TJ, Roxburgh CS, Horgan PG, Nixon C, Nourse C, Gunzer M, Clark W, Hedley A, Yilmaz OH, Rashid M, Bailey P, Biankin AV, Campbell AD, Adams DJ, Barry ST, Steele CW, Medema JP, Sansom OJ. PMID: 31526760; PMCID: PMC6853173.
      View in: PubMed   Mentions: 248     Fields:    Translation:HumansAnimalsCells
    106. α-Conotoxin Vc1.1 Structure-Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement. ACS Chem Neurosci. 2019 10 16; 10(10):4328-4336. Chu X, Tae HS, Xu Q, Jiang T, Adams DJ, Yu R. PMID: 31411453.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    107. Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis. Front Cardiovasc Med. 2019; 6:99. Nagy M, van Geffen JP, Stegner D, Adams DJ, Braun A, de Witt SM, Elvers M, Geer MJ, Kuijpers MJE, Kunzelmann K, Mori J, Oury C, Pircher J, Pleines I, Poole AW, Senis YA, Verdoold R, Weber C, Nieswandt B, Heemskerk JWM, Baaten CCFMJ. PMID: 31417909; PMCID: PMC6682619.
      View in: PubMed   Mentions: 9  
    108. Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets. Nat Commun. 2019 07 18; 10(1):3163. Newell F, Kong Y, Wilmott JS, Johansson PA, Ferguson PM, Cui C, Li Z, Kazakoff SH, Burke H, Dodds TJ, Patch AM, Nones K, Tembe V, Shang P, van der Weyden L, Wong K, Holmes O, Lo S, Leonard C, Wood S, Xu Q, Rawson RV, Mukhopadhyay P, Dummer R, Levesque MP, Jönsson G, Wang X, Yeh I, Wu H, Joseph N, Bastian BC, Long GV, Spillane AJ, Shannon KF, Thompson JF, Saw RPM, Adams DJ, Si L, Pearson JV, Hayward NK, Waddell N, Mann GJ, Guo J, Scolyer RA. PMID: 31320640; PMCID: PMC6639323.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansCells
    109. Bombesin receptors as potential targets for anticancer drug delivery and imaging. Int J Biochem Cell Biol. 2019 09; 114:105567. Pooja D, Gunukula A, Gupta N, Adams DJ, Kulhari H. PMID: 31295552.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    110. Common and distinct transcriptional signatures of mammalian embryonic lethality. Nat Commun. 2019 06 26; 10(1):2792. Collins JE, White RJ, Staudt N, Sealy IM, Packham I, Wali N, Tudor C, Mazzeo C, Green A, Siragher E, Ryder E, White JK, Papatheodoru I, Tang A, Füllgrabe A, Billis K, Geyer SH, Weninger WJ, Galli A, Hemberger M, Stemple DL, Robertson E, Smith JC, Mohun T, Adams DJ, Busch-Nentwich EM. PMID: 31243271; PMCID: PMC6594971.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    111. Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor. Br J Pharmacol. 2019 08; 176(15):2750-2763. Yu R, Tae HS, Xu Q, Craik DJ, Adams DJ, Jiang T, Kaas Q. PMID: 31062355; PMCID: PMC6609542.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    112. ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma. Nat Commun. 2019 05 17; 10(1):2213. Rashid M, van der Horst M, Mentzel T, Butera F, Ferreira I, Pance A, Rütten A, Luzar B, Marusic Z, de Saint Aubain N, Ko JS, Billings SD, Chen S, Abi Daoud M, Hewinson J, Louzada S, Harms PW, Cerretelli G, Robles-Espinoza CD, Patel RM, van der Weyden L, Bakal C, Hornick JL, Arends MJ, Brenn T, Adams DJ. PMID: 31101826; PMCID: PMC6525246.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    113. Analgesic transient receptor potential vanilloid-1-active compounds inhibit native and recombinant T-type calcium channels. Br J Pharmacol. 2019 07; 176(13):2264-2278. McArthur JR, Finol-Urdaneta RK, Adams DJ. PMID: 30927254; PMCID: PMC6555866.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    114. MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance. Nat Commun. 2019 05 02; 10(1):2030. Sale MJ, Balmanno K, Saxena J, Ozono E, Wojdyla K, McIntyre RE, Gilley R, Woroniuk A, Howarth KD, Hughes G, Dry JR, Arends MJ, Caro P, Oxley D, Ashton S, Adams DJ, Saez-Rodriguez J, Smith PD, Cook SJ. PMID: 31048689; PMCID: PMC6497655.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    115. Author Correction: An atlas of genetic influences on osteoporosis in humans and mice. Nat Genet. 2019 05; 51(5):920. Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco AL, Vijay J, Simon MM, Pramatarova A, Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum AT, Mannan NS, Komla-Ebri DSK, Pollard AS, Dewhurst HF, Hassall TAD, Beltejar MG, 23andMe Research Team, Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani EE, Evangelou E, Ohlsson C, Karasik D, Rivadeneira F, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Goltzman D, Adams DJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu YH, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB. PMID: 30988516.
      View in: PubMed   Mentions: 7     Fields:    
    116. Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma. JAMA Dermatol. 2019 05 01; 155(5):604-609. Wong K, Robles-Espinoza CD, Rodriguez D, Rudat SS, Puig S, Potrony M, Wong CC, Hewinson J, Aguilera P, Puig-Butille JA, Bressac-de Paillerets B, Zattara H, van der Weyden L, Fletcher CDM, Brenn T, Arends MJ, Quesada V, Newton-Bishop JA, Lopez-Otin C, Bishop DT, Harms PW, Johnson TM, Durham AB, Lombard DB, Adams DJ. PMID: 30586141; PMCID: PMC6506889.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    117. Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma. Nat Commun. 2019 01 21; 10(1):353. Wong K, van der Weyden L, Schott CR, Foote A, Constantino-Casas F, Smith S, Dobson JM, Murchison EP, Wu H, Yeh I, Fullen DR, Joseph N, Bastian BC, Patel RM, Martincorena I, Robles-Espinoza CD, Iyer V, Kuijjer ML, Arends MJ, Brenn T, Harms PW, Wood GA, Adams DJ. PMID: 30664638; PMCID: PMC6341101.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimals
    118. Drysdalin, an antagonist of nicotinic acetylcholine receptors highlights the importance of functional rather than structural conservation of amino acid residues. FASEB Bioadv. 2019 Feb; 1(2):115-131. Chandna R, Tae HS, Seymour VAL, Chathrath S, Adams DJ, Kini RM. PMID: 32123825; PMCID: PMC6996315.
      View in: PubMed   Mentions: 8  
    119. Monoclonal Antibody-Conjugated Dendritic Nanostructures for siRNA Delivery. Methods Mol Biol. 2019; 1974:195-201. Kulhari H, Jangid AK, Adams DJ. PMID: 31099004.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    120. An atlas of genetic influences on osteoporosis in humans and mice. Nat Genet. 2019 02; 51(2):258-266. Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco AL, Vijay J, Simon MM, Pramatarova A, Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum AT, Mannan NS, Komla-Ebri DSK, Pollard AS, Dewhurst HF, Hassall TAD, Beltejar MG, 23andMe Research Team, Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani EE, Evangelou E, Ohlsson C, Karasik D, Rivadeneira F, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Goltzman D, Adams DJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu YH, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB. PMID: 30598549; PMCID: PMC6358485.
      View in: PubMed   Mentions: 415     Fields:    Translation:HumansAnimals
    121. Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide. J Natl Cancer Inst. 2018 12 01; 110(12):1328-1341. Walpole S, Pritchard AL, Cebulla CM, Pilarski R, Stautberg M, Davidorf FH, de la Fouchardière A, Cabaret O, Golmard L, Stoppa-Lyonnet D, Garfield E, Njauw CN, Cheung M, Turunen JA, Repo P, Järvinen RS, van Doorn R, Jager MJ, Luyten GPM, Marinkovic M, Chau C, Potrony M, Höiom V, Helgadottir H, Pastorino L, Bruno W, Andreotti V, Dalmasso B, Ciccarese G, Queirolo P, Mastracci L, Wadt K, Kiilgaard JF, Speicher MR, van Poppelen N, Kilic E, Al-Jamal RT, Dianzani I, Betti M, Bergmann C, Santagata S, Dahiya S, Taibjee S, Burke J, Poplawski N, O'Shea SJ, Newton-Bishop J, Adlard J, Adams DJ, Lane AM, Kim I, Klebe S, Racher H, Harbour JW, Nickerson ML, Murali R, Palmer JM, Howlie M, Symmons J, Hamilton H, Warrier S, Glasson W, Johansson P, Robles-Espinoza CD, Ossio R, de Klein A, Puig S, Ghiorzo P, Nielsen M, Kivelä TT, Tsao H, Testa JR, Gerami P, Stern MH, Paillerets BB, Abdel-Rahman MH, Hayward NK. PMID: 30517737; PMCID: PMC6292796.
      View in: PubMed   Mentions: 115     Fields:    Translation:Humans
    122. Targeting of N-Type Calcium Channels via GABAB-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic Activity. J Med Chem. 2018 11 21; 61(22):10198-10205. Cai F, Xu N, Liu Z, Ding R, Yu S, Dong M, Wang S, Shen J, Tae HS, Adams DJ, Zhang X, Dai Q. PMID: 30358401.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    123. NMR Structure of μ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced NaV Channel Potency. Molecules. 2018 Oct 22; 23(10). Harvey PJ, Kurniawan ND, Finol-Urdaneta RK, McArthur JR, Van Lysebetten D, Dash TS, Hill JM, Adams DJ, Durek T, Craik DJ. PMID: 30360356; PMCID: PMC6222493.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    124. A lentiviral vector-based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma. Pigment Cell Melanoma Res. 2019 03; 32(2):332-335. Ranzani M, Alifrangis C, Thompson NA, Rust AG, Allahyar A, Iyer V, Price S, Ellis P, Turner G, de Ridder J, McDermott U, Adams DJ. PMID: 30218636.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    125. Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci. Nat Genet. 2018 11; 50(11):1574-1583. Lilue J, Doran AG, Fiddes IT, Abrudan M, Armstrong J, Bennett R, Chow W, Collins J, Collins S, Czechanski A, Danecek P, Diekhans M, Dolle DD, Dunn M, Durbin R, Earl D, Ferguson-Smith A, Flicek P, Flint J, Frankish A, Fu B, Gerstein M, Gilbert J, Goodstadt L, Harrow J, Howe K, Ibarra-Soria X, Kolmogorov M, Lelliott CJ, Logan DW, Loveland J, Mathews CE, Mott R, Muir P, Nachtweide S, Navarro FCP, Odom DT, Park N, Pelan S, Pham SK, Quail M, Reinholdt L, Romoth L, Shirley L, Sisu C, Sjoberg-Herrera M, Stanke M, Steward C, Thomas M, Threadgold G, Thybert D, Torrance J, Wong K, Wood J, Yalcin B, Yang F, Adams DJ, Paten B, Keane TM. PMID: 30275530; PMCID: PMC6205630.
      View in: PubMed   Mentions: 145     Fields:    Translation:Animals
    126. Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides. Sci Rep. 2018 09 07; 8(1):13397. Sousa SR, McArthur JR, Brust A, Bhola RF, Rosengren KJ, Ragnarsson L, Dutertre S, Alewood PF, Christie MJ, Adams DJ, Vetter I, Lewis RJ. PMID: 30194442; PMCID: PMC6128854.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    127. Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB. Biochem Pharmacol. 2018 09; 155:288-297. Wu X, Tae HS, Huang YH, Adams DJ, Craik DJ, Kaas Q. PMID: 30009767.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    128. Structure-Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by α-Conotoxin Vc1.1. ACS Chem Biol. 2018 06 15; 13(6):1577-1587. Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae HS, O'Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ. PMID: 29746088.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    129. Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor Subtype. J Med Chem. 2018 05 24; 61(10):4628-4634. Yu R, Tae HS, Tabassum N, Shi J, Jiang T, Adams DJ. PMID: 29733583.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    130. Contribution of membrane receptor signalling to chronic visceral pain. Int J Biochem Cell Biol. 2018 05; 98:10-23. Sadeghi M, Erickson A, Castro J, Deiteren A, Harrington AM, Grundy L, Adams DJ, Brierley SM. PMID: 29477359.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    131. Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain. Br J Pharmacol. 2018 06; 175(12):2384-2398. Castro J, Grundy L, Deiteren A, Harrington AM, O'Donnell T, Maddern J, Moore J, Garcia-Caraballo S, Rychkov GY, Yu R, Kaas Q, Craik DJ, Adams DJ, Brierley SM. PMID: 29194563; PMCID: PMC5980271.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    132. A novel α-conopeptide Eu1.6 inhibits N-type (CaV2.2) calcium channels and exhibits potent analgesic activity. Sci Rep. 2018 01 17; 8(1):1004. Liu Z, Bartels P, Sadeghi M, Du T, Dai Q, Zhu C, Yu S, Wang S, Dong M, Sun T, Guo J, Peng S, Jiang L, Adams DJ, Dai Q. PMID: 29343689; PMCID: PMC5772529.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    133. Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors. Sci Rep. 2017 11 30; 7(1):16606. Durek T, Shelukhina IV, Tae HS, Thongyoo P, Spirova EN, Kudryavtsev DS, Kasheverov IE, Faure G, Corringer PJ, Craik DJ, Adams DJ, Tsetlin VI. PMID: 29192197; PMCID: PMC5709491.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    134. Neuropharmacology of venom peptides. Neuropharmacology. 2017 12; 127:1-3. Adams DJ, Lewis RJ. PMID: 29154773.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    135. A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction. Nat Commun. 2017 10 12; 8(1):886. Bowl MR, Simon MM, Ingham NJ, Greenaway S, Santos L, Cater H, Taylor S, Mason J, Kurbatova N, Pearson S, Bower LR, Clary DA, Meziane H, Reilly P, Minowa O, Kelsey L, International Mouse Phenotyping Consortium, Tocchini-Valentini GP, Gao X, Bradley A, Skarnes WC, Moore M, Beaudet AL, Justice MJ, Seavitt J, Dickinson ME, Wurst W, de Angelis MH, Herault Y, Wakana S, Nutter LMJ, Flenniken AM, McKerlie C, Murray SA, Svenson KL, Braun RE, West DB, Lloyd KCK, Adams DJ, White J, Karp N, Flicek P, Smedley D, Meehan TF, Parkinson HE, Teboul LM, Wells S, Steel KP, Mallon AM, Brown SDM. PMID: 29026089; PMCID: PMC5638796.
      View in: PubMed   Mentions: 95     Fields:    Translation:Animals
    136. In vivo and in vitro testing of native α-conotoxins from the injected venom of Conus purpurascens. Neuropharmacology. 2017 Dec; 127:253-259. Hoggard MF, Rodriguez AM, Cano H, Clark E, Tae HS, Adams DJ, Godenschwege TA, Marí F. PMID: 28917942.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    137. Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis. Nat Genet. 2017 Oct; 49(10):1468-1475. Kemp JP, Morris JA, Medina-Gomez C, Forgetta V, Warrington NM, Youlten SE, Zheng J, Gregson CL, Grundberg E, Trajanoska K, Logan JG, Pollard AS, Sparkes PC, Ghirardello EJ, Allen R, Leitch VD, Butterfield NC, Komla-Ebri D, Adoum AT, Curry KF, White JK, Kussy F, Greenlaw KM, Xu C, Harvey NC, Cooper C, Adams DJ, Greenwood CMT, Maurano MT, Kaptoge S, Rivadeneira F, Tobias JH, Croucher PI, Ackert-Bicknell CL, Bassett JHD, Williams GR, Richards JB, Evans DM. PMID: 28869591; PMCID: PMC5621629.
      View in: PubMed   Mentions: 258     Fields:    Translation:HumansAnimalsCells
    138. Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. J Biol Chem. 2017 10 13; 292(41):17101-17112. Wu X, Huang YH, Kaas Q, Harvey PJ, Wang CK, Tae HS, Adams DJ, Craik DJ. PMID: 28851841; PMCID: PMC5641895.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    139. Role of CysI-CysIII Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors. ACS Omega. 2017 Aug 31; 2(8):4621-4631. Tabassum N, Tae HS, Jia X, Kaas Q, Jiang T, Adams DJ, Yu R. PMID: 30023726; PMCID: PMC6044955.
      View in: PubMed   Mentions: 7  
    140. Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1. Br J Pharmacol. 2018 06; 175(12):2284-2295. McArthur JR, Motin L, Gleeson EC, Spiller S, Lewis RJ, Duggan PJ, Tuck KL, Adams DJ. PMID: 28608537; PMCID: PMC5980596.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    141. Identifying transposon insertions and their effects from RNA-sequencing data. Nucleic Acids Res. 2017 Jul 07; 45(12):7064-7077. de Ruiter JR, Kas SM, Schut E, Adams DJ, Koudijs MJ, Wessels LFA, Jonkers J. PMID: 28575524; PMCID: PMC5499543.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    142. Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium. Nat Genet. 2017 Aug; 49(8):1231-1238. Meehan TF, Conte N, West DB, Jacobsen JO, Mason J, Warren J, Chen CK, Tudose I, Relac M, Matthews P, Karp N, Santos L, Fiegel T, Ring N, Westerberg H, Greenaway S, Sneddon D, Morgan H, Codner GF, Stewart ME, Brown J, Horner N, International Mouse Phenotyping Consortium, Haendel M, Washington N, Mungall CJ, Reynolds CL, Gallegos J, Gailus-Durner V, Sorg T, Pavlovic G, Bower LR, Moore M, Morse I, Gao X, Tocchini-Valentini GP, Obata Y, Cho SY, Seong JK, Seavitt J, Beaudet AL, Dickinson ME, Herault Y, Wurst W, de Angelis MH, Lloyd KCK, Flenniken AM, Nutter LMJ, Newbigging S, McKerlie C, Justice MJ, Murray SA, Svenson KL, Braun RE, White JK, Bradley A, Flicek P, Wells S, Skarnes WC, Adams DJ, Parkinson H, Mallon AM, Brown SDM, Smedley D. PMID: 28650483; PMCID: PMC5546242.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimals
    143. Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma. Nat Genet. 2017 Aug; 49(8):1219-1230. Kas SM, de Ruiter JR, Schipper K, Annunziato S, Schut E, Klarenbeek S, Drenth AP, van der Burg E, Klijn C, Ten Hoeve JJ, Adams DJ, Koudijs MJ, Wesseling J, Nethe M, Wessels LFA, Jonkers J. PMID: 28650484.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    144. Peptide grafted and self-assembled poly(γ-glutamic acid)-phenylalanine nanoparticles targeting camptothecin to glioma. Nanomedicine (Lond). 2017 Jul; 12(14):1661-1674. Kulhari H, Telukutla SR, Pooja D, Shukla R, Sistla R, Bansal V, Adams DJ. PMID: 28635550.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    145. α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition. Br J Pharmacol. 2018 06; 175(11):1855-1868. Cuny H, Yu R, Tae HS, Kompella SN, Adams DJ. PMID: 28477355; PMCID: PMC5979624.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    146. Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor. Mar Drugs. 2017 Jun 09; 15(6). Jiang S, Tae HS, Xu S, Shao X, Adams DJ, Wang C. PMID: 28598389; PMCID: PMC5484120.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    147. A Novel Lid-Covering Peptide Inhibitor of Nicotinic Acetylcholine Receptors Derived from αD-Conotoxin GeXXA. Mar Drugs. 2017 Jun 05; 15(6). Yang L, Tae HS, Fan Z, Shao X, Xu S, Zhao S, Adams DJ, Wang C. PMID: 28587231; PMCID: PMC5484114.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    148. Analgesic conopeptides targeting G protein-coupled receptors reduce excitability of sensory neurons. Neuropharmacology. 2017 Dec; 127:116-123. Sadeghi M, McArthur JR, Finol-Urdaneta RK, Adams DJ. PMID: 28533165.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    149. The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity. Sci Rep. 2017 04 20; 7(1):974. Wingerd JS, Mozar CA, Ussing CA, Murali SS, Chin YK, Cristofori-Armstrong B, Durek T, Gilchrist J, Vaughan CW, Bosmans F, Adams DJ, Lewis RJ, Alewood PF, Mobli M, Christie MJ, Rash LD. PMID: 28428547; PMCID: PMC5430537.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    150. Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification. Proc Natl Acad Sci U S A. 2017 03 14; 114(11):E2215-E2224. Chen L, Jenjaroenpun P, Pillai AM, Ivshina AV, Ow GS, Efthimios M, Zhiqun T, Tan TZ, Lee SC, Rogers K, Ward JM, Mori S, Adams DJ, Jenkins NA, Copeland NG, Ban KH, Kuznetsov VA, Thiery JP. PMID: 28251929; PMCID: PMC5358385.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    151. HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation. EMBO Mol Med. 2017 02; 9(2):181-197. Myant KB, Cammareri P, Hodder MC, Wills J, Von Kriegsheim A, Gyorffy B, Rashid M, Polo S, Maspero E, Vaughan L, Gurung B, Barry E, Malliri A, Camargo F, Adams DJ, Iavarone A, Lasorella A, Sansom OJ. PMID: 28003334; PMCID: PMC5286368.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    152. Combined immunodeficiency with severe inflammation and allergy caused by ARPC1B deficiency. J Allergy Clin Immunol. 2017 07; 140(1):273-277.e10. Kuijpers TW, Tool ATJ, van der Bijl I, de Boer M, van Houdt M, de Cuyper IM, Roos D, van Alphen F, van Leeuwen K, Cambridge EL, Arends MJ, Dougan G, Clare S, Ramirez-Solis R, Pals ST, Adams DJ, Meijer AB, van den Berg TK. PMID: 27965109.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimals
    153. Effects of linker sequence modifications on the structure, stability, and biological activity of a cyclic α-conotoxin. Biopolymers. 2016 Nov; 106(6):864-875. Carstens BB, Swedberg J, Berecki G, Adams DJ, Craik DJ, Clark RJ. PMID: 27038328.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    154. Store-Operated Ca2+ Entry (SOCE) and Purinergic Receptor-Mediated Ca2+ Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation. Front Mol Neurosci. 2016; 9:111. Gilbert DF, Stebbing MJ, Kuenzel K, Murphy RM, Zacharewicz E, Buttgereit A, Stokes L, Adams DJ, Friedrich O. PMID: 27840602; PMCID: PMC5083710.
      View in: PubMed   Mentions: 21  
    155. Improving Efficacy, Oral Bioavailability, and Delivery of Paclitaxel Using Protein-Grafted Solid Lipid Nanoparticles. Mol Pharm. 2016 11 07; 13(11):3903-3912. Pooja D, Kulhari H, Kuncha M, Rachamalla SS, Adams DJ, Bansal V, Sistla R. PMID: 27696858.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    156. Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins. J Biol Chem. 2016 Nov 04; 291(45):23779-23792. Cuny H, Kompella SN, Tae HS, Yu R, Adams DJ. PMID: 27646000; PMCID: PMC5095430.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    157. High-throughput discovery of novel developmental phenotypes. Nature. 2016 09 22; 537(7621):508-514. Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, International Mouse Phenotyping Consortium, Jackson Laboratory, Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS), Charles River Laboratories, MRC Harwell, Toronto Centre for Phenogenomics, Wellcome Trust Sanger Institute, RIKEN BioResource Center, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bucan M, Murray SA. PMID: 27626380; PMCID: PMC5295821.
      View in: PubMed   Mentions: 726     Fields:    Translation:HumansAnimalsCells
    158. A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice. G3 (Bethesda). 2016 08 09; 6(8):2343-54. McIntyre RE, Nicod J, Robles-Espinoza CD, Maciejowski J, Cai N, Hill J, Verstraten R, Iyer V, Rust AG, Balmus G, Mott R, Flint J, Adams DJ. PMID: 27233670; PMCID: PMC4978889.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    159. Germline MC1R status influences somatic mutation burden in melanoma. Nat Commun. 2016 07 12; 7:12064. Robles-Espinoza CD, Roberts ND, Chen S, Leacy FP, Alexandrov LB, Pornputtapong N, Halaban R, Krauthammer M, Cui R, Timothy Bishop D, Adams DJ. PMID: 27403562; PMCID: PMC4945874.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    160. Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing. Nat Genet. 2016 08; 48(8):912-8. Nicod J, Davies RW, Cai N, Hassett C, Goodstadt L, Cosgrove C, Yee BK, Lionikaite V, McIntyre RE, Remme CA, Lodder EM, Gregory JS, Hough T, Joynson R, Phelps H, Nell B, Rowe C, Wood J, Walling A, Bopp N, Bhomra A, Hernandez-Pliego P, Callebert J, Aspden RM, Talbot NP, Robbins PA, Harrison M, Fray M, Launay JM, Pinto YM, Blizard DA, Bezzina CR, Adams DJ, Franken P, Weaver T, Wells S, Brown SD, Potter PK, Klenerman P, Lionikas A, Mott R, Flint J. PMID: 27376238; PMCID: PMC4966644.
      View in: PubMed   Mentions: 87     Fields:    Translation:Animals
    161. Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer. Proc Natl Acad Sci U S A. 2016 07 19; 113(29):8290-5. Ahmad I, Mui E, Galbraith L, Patel R, Tan EH, Salji M, Rust AG, Repiscak P, Hedley A, Markert E, Loveridge C, van der Weyden L, Edwards J, Sansom OJ, Adams DJ, Leung HY. PMID: 27357679; PMCID: PMC4961202.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    162. Formulation and dosage of therapeutic nanosuspension for active targeting of docetaxel (WO 2014210485A1). Expert Opin Ther Pat. 2016 Jul; 26(7):745-9. Pooja D, Kulhari H, Adams DJ, Sistla R. PMID: 27088623.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    163. Mechanism of direct Cav2.2 channel block by the κ-opioid receptor agonist U50488H. Neuropharmacology. 2016 10; 109:49-58. Berecki G, Motin L, Adams DJ. PMID: 27245500.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    164. Trastuzumab-grafted PAMAM dendrimers for the selective delivery of anticancer drugs to HER2-positive breast cancer. Sci Rep. 2016 Apr 07; 6:23179. Kulhari H, Pooja D, Shrivastava S, Kuncha M, Naidu VGM, Bansal V, Sistla R, Adams DJ. PMID: 27052896; PMCID: PMC4823704.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    165. Cyclic RGDfK Peptide Functionalized Polymeric Nanocarriers for Targeting Gemcitabine to Ovarian Cancer Cells. Mol Pharm. 2016 05 02; 13(5):1491-500. Kulhari H, Pooja D, Kota R, Reddy TS, Tabor RF, Shukla R, Adams DJ, Sistla R, Bansal V. PMID: 26930230.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    166. Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABA(B) Receptor Activation Reveal a Minimal Functional Motif. Angew Chem Int Ed Engl. 2016 Apr 04; 55(15):4692-6. Carstens BB, Berecki G, Daniel JT, Lee HS, Jackson KA, Tae HS, Sadeghi M, Castro J, O'Donnell T, Deiteren A, Brierley SM, Craik DJ, Adams DJ, Clark RJ. PMID: 26948522.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    167. α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors. Gut. 2017 06; 66(6):1083-1094. Castro J, Harrington AM, Garcia-Caraballo S, Maddern J, Grundy L, Zhang J, Page G, Miller PE, Craik DJ, Adams DJ, Brierley SM. PMID: 26887818; PMCID: PMC5532460.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    168. Germline TERT promoter mutations are rare in familial melanoma. Fam Cancer. 2016 Jan; 15(1):139-44. Harland M, Petljak M, Robles-Espinoza CD, Ding Z, Gruis NA, van Doorn R, Pooley KA, Dunning AM, Aoude LG, Wadt KA, Gerdes AM, Brown KM, Hayward NK, Newton-Bishop JA, Adams DJ, Bishop DT. PMID: 26433962; PMCID: PMC4698275.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    169. Modulation of human Nav1.7 channel gating by synthetic α-scorpion toxin OD1 and its analogs. Channels (Austin). 2016; 10(2):139-47. Motin L, Durek T, Adams DJ. PMID: 26646206; PMCID: PMC4960991.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    170. Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes. J Pathol. 2016 Jan; 238(1):98-108. Rashid M, Fischer A, Wilson CH, Tiffen J, Rust AG, Stevens P, Idziaszczyk S, Maynard J, Williams GT, Mustonen V, Sampson JR, Adams DJ. PMID: 26414517; PMCID: PMC4832337.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    171. Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins. Biopolymers. 2015 Nov; 104(6):682-92. Akcan M, Clark RJ, Daly NL, Conibear AC, de Faoite A, Heghinian MD, Sahil T, Adams DJ, Marí F, Craik DJ. PMID: 26172377.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    172. Voltage-Gated R-Type Calcium Channel Inhibition via Human μ-, δ-, and κ-opioid Receptors Is Voltage-Independently Mediated by Gβγ Protein Subunits. Mol Pharmacol. 2016 Jan; 89(1):187-96. Berecki G, Motin L, Adams DJ. PMID: 26490245.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    173. The utility of transposon mutagenesis for cancer studies in the era of genome editing. Genome Biol. 2015 Oct 19; 16:229. DeNicola GM, Karreth FA, Adams DJ, Wong CC. PMID: 26481584; PMCID: PMC4612416.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    174. A Distinct Functional Site in Ω-Neurotoxins: Novel Antagonists of Nicotinic Acetylcholine Receptors from Snake Venom. ACS Chem Biol. 2015 Dec 18; 10(12):2805-15. Hassan-Puttaswamy V, Adams DJ, Kini RM. PMID: 26448325.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    175. Molecular Basis for Differential Sensitivity of α-Conotoxin RegIIA at Rat and Human Neuronal Nicotinic Acetylcholine Receptors. Mol Pharmacol. 2015 Dec; 88(6):993-1001. Kompella SN, Cuny H, Hung A, Adams DJ. PMID: 26438212.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    176. Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors. Sci Rep. 2015 Sep 23; 5:14261. Xu S, Zhang T, Kompella SN, Yan M, Lu A, Wang Y, Shao X, Chi C, Adams DJ, Ding J, Wang C. PMID: 26395518; PMCID: PMC4585798.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    177. Bombesin-conjugated nanoparticles improve the cytotoxic efficacy of docetaxel against gastrin-releasing but androgen-independent prostate cancer. Nanomedicine (Lond). 2015; 10(18):2847-59. Kulhari H, Pooja D, Singh MK, Kuncha M, Adams DJ, Sistla R. PMID: 26377157.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    178. A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression. J Exp Med. 2015 Sep 21; 212(10):1551-69. Giotopoulos G, van der Weyden L, Osaki H, Rust AG, Gallipoli P, Meduri E, Horton SJ, Chan WI, Foster D, Prinjha RK, Pimanda JE, Tenen DG, Vassiliou GS, Koschmieder S, Adams DJ, Huntly BJ. PMID: 26304963; PMCID: PMC4577832.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    179. Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1. Sci Rep. 2015 Aug 20; 5:13264. Yu R, Seymour VA, Berecki G, Jia X, Akcan M, Adams DJ, Kaas Q, Craik DJ. PMID: 26290113; PMCID: PMC4542547.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    180. Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia. BMC Cancer. 2015 Aug 13; 15:585. van der Weyden L, Giotopoulos G, Wong K, Rust AG, Robles-Espinoza CD, Osaki H, Huntly BJ, Adams DJ. PMID: 26269126; PMCID: PMC4542115.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    181. Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics. Nat Genet. 2015 Sep; 47(9):969-978. de Angelis MH, Nicholson G, Selloum M, White J, Morgan H, Ramirez-Solis R, Sorg T, Wells S, Fuchs H, Fray M, Adams DJ, Adams NC, Adler T, Aguilar-Pimentel A, Ali-Hadji D, Amann G, André P, Atkins S, Auburtin A, Ayadi A, Becker J, Becker L, Bedu E, Bekeredjian R, Birling MC, Blake A, Bottomley J, Bowl M, Brault V, Busch DH, Bussell JN, Calzada-Wack J, Cater H, Champy MF, Charles P, Chevalier C, Chiani F, Codner GF, Combe R, Cox R, Dalloneau E, Dierich A, Di Fenza A, Doe B, Duchon A, Eickelberg O, Esapa CT, El Fertak L, Feigel T, Emelyanova I, Estabel J, Favor J, Flenniken A, Gambadoro A, Garrett L, Gates H, Gerdin AK, Gkoutos G, Greenaway S, Glasl L, Goetz P, Da Cruz IG, Götz A, Graw J, Guimond A, Hans W, Hicks G, Hölter SM, Höfler H, Hancock JM, Hoehndorf R, Hough T, Houghton R, Hurt A, Ivandic B, Jacobs H, Jacquot S, Jones N, Karp NA, Katus HA, Kitchen S, Klein-Rodewald T, Klingenspor M, Klopstock T, Lalanne V, Leblanc S, Lengger C, le Marchand E, Ludwig T, Lux A, McKerlie C, Maier H, Mandel JL, Marschall S, Mark M, Melvin DG, Meziane H, Micklich K, Mittelhauser C, Monassier L, Moulaert D, Muller S, Naton B, Neff F, Nolan PM, Nutter LM, Ollert M, Pavlovic G, Pellegata NS, Peter E, Petit-Demoulière B, Pickard A, Podrini C, Potter P, Pouilly L, Puk O, Richardson D, Rousseau S, Quintanilla-Fend L, Quwailid MM, Racz I, Rathkolb B, Riet F, Rossant J, Roux M, Rozman J, Ryder E, Salisbury J, Santos L, Schäble KH, Schiller E, Schrewe A, Schulz H, Steinkamp R, Simon M, Stewart M, Stöger C, Stöger T, Sun M, Sunter D, Teboul L, Tilly I, Tocchini-Valentini GP, Tost M, Treise I, Vasseur L, Velot E, Vogt-Weisenhorn D, Wagner C, Walling A, Weber B, Wendling O, Westerberg H, Willershäuser M, Wolf E, Wolter A, Wood J, Wurst W, Yildirim AÖ, Zeh R, Zimmer A, Zimprich A, EUMODIC Consortium, Holmes C, Steel KP, Herault Y, Gailus-Durner V, Mallon AM, Brown SD. PMID: 26214591; PMCID: PMC4564951.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimals
    182. Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours. Nanomedicine. 2015 Aug; 11(6):1511-20. Kulhari H, Pooja D, Shrivastava S, Telukutala SR, Barui AK, Patra CR, Naidu Vegi GM, Adams DJ, Sistla R. PMID: 25933692.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    183. PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia. Blood. 2015 Jun 04; 125(23):3609-17. Dang J, Wei L, de Ridder J, Su X, Rust AG, Roberts KG, Payne-Turner D, Cheng J, Ma J, Qu C, Wu G, Song G, Huether RG, Schulman B, Janke L, Zhang J, Downing JR, van der Weyden L, Adams DJ, Mullighan CG. PMID: 25855603; PMCID: PMC4458800.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    184. The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo. Cell. 2015 Apr 09; 161(2):319-32. Karreth FA, Reschke M, Ruocco A, Ng C, Chapuy B, Léopold V, Sjoberg M, Keane TM, Verma A, Ala U, Tay Y, Wu D, Seitzer N, Velasco-Herrera Mdel C, Bothmer A, Fung J, Langellotto F, Rodig SJ, Elemento O, Shipp MA, Adams DJ, Chiarle R, Pandolfi PP. PMID: 25843629; PMCID: PMC6922011.
      View in: PubMed   Mentions: 183     Fields:    Translation:HumansAnimalsCells
    185. Biomedical applications of trastuzumab: as a therapeutic agent and a targeting ligand. Med Res Rev. 2015 Jul; 35(4):849-76. Kulhari H, Pooja D, Rompicharla SV, Sistla R, Adams DJ. PMID: 25847027.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    186. α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors. J Am Chem Soc. 2015 Mar 11; 137(9):3209-12. Wan J, Huang JX, Vetter I, Mobli M, Lawson J, Tae HS, Abraham N, Paul B, Cooper MA, Adams DJ, Lewis RJ, Alewood PF. PMID: 25710197.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    187. BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model. Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6):E536-45. Perna D, Karreth FA, Rust AG, Perez-Mancera PA, Rashid M, Iorio F, Alifrangis C, Arends MJ, Bosenberg MW, Bollag G, Tuveson DA, Adams DJ. PMID: 25624498; PMCID: PMC4330752.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    188. Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression. Nat Genet. 2015 Feb; 47(2):142-50. Takeda H, Wei Z, Koso H, Rust AG, Yew CC, Mann MB, Ward JM, Adams DJ, Copeland NG, Jenkins NA. PMID: 25559195.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    189. Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma. J Natl Cancer Inst. 2015 Feb; 107(2). Aoude LG, Pritchard AL, Robles-Espinoza CD, Wadt K, Harland M, Choi J, Gartside M, Quesada V, Johansson P, Palmer JM, Ramsay AJ, Zhang X, Jones K, Symmons J, Holland EA, Schmid H, Bonazzi V, Woods S, Dutton-Regester K, Stark MS, Snowden H, van Doorn R, Montgomery GW, Martin NG, Keane TM, López-Otín C, Gerdes AM, Olsson H, Ingvar C, Borg A, Gruis NA, Trent JM, Jönsson G, Bishop DT, Mann GJ, Newton-Bishop JA, Brown KM, Adams DJ, Hayward NK. PMID: 25505254; PMCID: PMC4334787.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansCells
    190. Inhibition of cholinergic pathways in Drosophila melanogaster by α-conotoxins. FASEB J. 2015 Mar; 29(3):1011-8. Heghinian MD, Mejia M, Adams DJ, Godenschwege TA, Marí F. PMID: 25466886; PMCID: PMC4422358.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    191. Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets. J Med Chem. 2014 Dec 11; 57(23):9933-44. Chhabra S, Belgi A, Bartels P, van Lierop BJ, Robinson SD, Kompella SN, Hung A, Callaghan BP, Adams DJ, Robinson AJ, Norton RS. PMID: 25393758.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    192. Novel mechanism of voltage-gated N-type (Cav2.2) calcium channel inhibition revealed through α-conotoxin Vc1.1 activation of the GABA(B) receptor. Mol Pharmacol. 2015 Feb; 87(2):240-50. Huynh TG, Cuny H, Slesinger PA, Adams DJ. PMID: 25425625.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    193. Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist. J Biol Chem. 2015 Jan 09; 290(2):1039-48. Kompella SN, Hung A, Clark RJ, Marí F, Adams DJ. PMID: 25411242; PMCID: PMC4294472.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    194. The mutational landscapes of genetic and chemical models of Kras-driven lung cancer. Nature. 2015 Jan 22; 517(7535):489-92. Westcott PM, Halliwill KD, To MD, Rashid M, Rust AG, Keane TM, Delrosario R, Jen KY, Gurley KE, Kemp CJ, Fredlund E, Quigley DA, Adams DJ, Balmain A. PMID: 25363767; PMCID: PMC4304785.
      View in: PubMed   Mentions: 201     Fields:    Translation:HumansAnimals
    195. Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors. Biochem Pharmacol. 2014 Oct 15; 91(4):534-42. Hopping G, Wang CI, Hogg RC, Nevin ST, Lewis RJ, Adams DJ, Alewood PF. PMID: 25101833.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    196. Differential Cav2.1 and Cav2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABAB receptor activation. J Gen Physiol. 2014 Apr; 143(4):465-79. Berecki G, McArthur JR, Cuny H, Clark RJ, Adams DJ. PMID: 24688019; PMCID: PMC3971658.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    197. POT1 loss-of-function variants predispose to familial melanoma. Nat Genet. 2014 May; 46(5):478-481. Robles-Espinoza CD, Harland M, Ramsay AJ, Aoude LG, Quesada V, Ding Z, Pooley KA, Pritchard AL, Tiffen JC, Petljak M, Palmer JM, Symmons J, Johansson P, Stark MS, Gartside MG, Snowden H, Montgomery GW, Martin NG, Liu JZ, Choi J, Makowski M, Brown KM, Dunning AM, Keane TM, López-Otín C, Gruis NA, Hayward NK, Bishop DT, Newton-Bishop JA, Adams DJ. PMID: 24686849; PMCID: PMC4266105.
      View in: PubMed   Mentions: 214     Fields:    Translation:HumansCells
    198. Identification of FoxR2 as an oncogene in medulloblastoma. Cancer Res. 2014 Apr 15; 74(8):2351-61. Koso H, Tsuhako A, Lyons E, Ward JM, Rust AG, Adams DJ, Jenkins NA, Copeland NG, Watanabe S. PMID: 24599127.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    199. Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis. PLoS Genet. 2014 Feb; 10(2):e1004167. Huser CA, Gilroy KL, de Ridder J, Kilbey A, Borland G, Mackay N, Jenkins A, Bell M, Herzyk P, van der Weyden L, Adams DJ, Rust AG, Cameron E, Neil JC. PMID: 24586197; PMCID: PMC3937229.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    200. Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels. Biochem Pharmacol. 2014 May 15; 89(2):276-86. Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD. PMID: 24561180.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    201. Inactivating CUX1 mutations promote tumorigenesis. Nat Genet. 2014 Jan; 46(1):33-8. Wong CC, Martincorena I, Rust AG, Rashid M, Alifrangis C, Alexandrov LB, Tiffen JC, Kober C, Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium, Green AR, Massie CE, Nangalia J, Lempidaki S, Döhner H, Döhner K, Bray SJ, McDermott U, Papaemmanuil E, Campbell PJ, Adams DJ. PMID: 24316979; PMCID: PMC3874239.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    202. Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model. Nat Genet. 2014 Jan; 46(1):24-32. Bard-Chapeau EA, Nguyen AT, Rust AG, Sayadi A, Lee P, Chua BQ, New LS, de Jong J, Ward JM, Chin CK, Chew V, Toh HC, Abastado JP, Benoukraf T, Soong R, Bard FA, Dupuy AJ, Johnson RL, Radda GK, Chan EC, Wessels LF, Adams DJ, Jenkins NA, Copeland NG. PMID: 24316982; PMCID: PMC4131144.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    203. Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):E4325-34. Genovesi LA, Ng CG, Davis MJ, Remke M, Taylor MD, Adams DJ, Rust AG, Ward JM, Ban KH, Jenkins NA, Copeland NG, Wainwright BJ. PMID: 24167280; PMCID: PMC3832011.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    204. Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors. J Biol Chem. 2013 Nov 29; 288(48):34428-42. Grishin AA, Cuny H, Hung A, Clark RJ, Brust A, Akondi K, Alewood PF, Craik DJ, Adams DJ. PMID: 24100032; PMCID: PMC3843058.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    205. Cancer gene discovery: exploiting insertional mutagenesis. Mol Cancer Res. 2013 Oct; 11(10):1141-58. Ranzani M, Annunziato S, Adams DJ, Montini E. PMID: 23928056; PMCID: PMC3836224.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    206. Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochem Pharmacol. 2013 Sep 15; 86(6):791-9. Inserra MC, Kompella SN, Vetter I, Brust A, Daly NL, Cuny H, Craik DJ, Alewood PF, Adams DJ, Lewis RJ. PMID: 23924607.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    207. Identification of a neuronal transcription factor network involved in medulloblastoma development. Acta Neuropathol Commun. 2013 Jul 11; 1:35. Lastowska M, Al-Afghani H, Al-Balool HH, Sheth H, Mercer E, Coxhead JM, Redfern CP, Peters H, Burt AD, Santibanez-Koref M, Bacon CM, Chesler L, Rust AG, Adams DJ, Williamson D, Clifford SC, Jackson MS. PMID: 24252690; PMCID: PMC3893591.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    208. Cake: a bioinformatics pipeline for the integrated analysis of somatic variants in cancer genomes. Bioinformatics. 2013 Sep 01; 29(17):2208-10. Rashid M, Robles-Espinoza CD, Rust AG, Adams DJ. PMID: 23803469; PMCID: PMC3740632.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    209. Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors. ACS Chem Biol. 2013 Aug 16; 8(8):1815-21. van Lierop BJ, Robinson SD, Kompella SN, Belgi A, McArthur JR, Hung A, MacRaild CA, Adams DJ, Norton RS, Robinson AJ. PMID: 23768016.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    210. Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors. PLoS One. 2013; 8(5):e62113. Klijn C, Koudijs MJ, Kool J, ten Hoeve J, Boer M, de Moes J, Akhtar W, van Miltenburg M, Vendel-Zwaagstra A, Reinders MJ, Adams DJ, van Lohuizen M, Hilkens J, Wessels LF, Jonkers J. PMID: 23690930; PMCID: PMC3653918.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    211. Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor. J Med Chem. 2013 May 09; 56(9):3557-67. Yu R, Kompella SN, Adams DJ, Craik DJ, Kaas Q. PMID: 23566299.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    212. Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1. ACS Chem Biol. 2013; 8(6):1215-22. Durek T, Vetter I, Wang CI, Motin L, Knapp O, Adams DJ, Lewis RJ, Alewood PF. PMID: 23527544.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    213. Mechanisms of conotoxin inhibition of N-type (Ca(v)2.2) calcium channels. Biochim Biophys Acta. 2013 Jul; 1828(7):1619-28. Adams DJ, Berecki G. PMID: 23380425.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimals
    214. Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome. PLoS Genet. 2012; 8(11):e1003022. McIntyre RE, Lakshminarasimhan Chavali P, Ismail O, Carragher DM, Sanchez-Andrade G, Forment JV, Fu B, Del Castillo Velasco-Herrera M, Edwards A, van der Weyden L, Yang F, Sanger Mouse Genetics Project, Ramirez-Solis R, Estabel J, Gallagher FA, Logan DW, Arends MJ, Tsang SH, Mahajan VB, Scudamore CL, White JK, Jackson SP, Gergely F, Adams DJ. PMID: 23166506; PMCID: PMC3499256.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    215. Conotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics? Toxins (Basel). 2012 Nov 08; 4(11):1236-60. Knapp O, McArthur JR, Adams DJ. PMID: 23202314; PMCID: PMC3509706.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    216. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature. 2012 Nov 15; 491(7424):399-405. Biankin AV, Waddell N, Kassahn KS, Gingras MC, Muthuswamy LB, Johns AL, Miller DK, Wilson PJ, Patch AM, Wu J, Chang DK, Cowley MJ, Gardiner BB, Song S, Harliwong I, Idrisoglu S, Nourse C, Nourbakhsh E, Manning S, Wani S, Gongora M, Pajic M, Scarlett CJ, Gill AJ, Pinho AV, Rooman I, Anderson M, Holmes O, Leonard C, Taylor D, Wood S, Xu Q, Nones K, Fink JL, Christ A, Bruxner T, Cloonan N, Kolle G, Newell F, Pinese M, Mead RS, Humphris JL, Kaplan W, Jones MD, Colvin EK, Nagrial AM, Humphrey ES, Chou A, Chin VT, Chantrill LA, Mawson A, Samra JS, Kench JG, Lovell JA, Daly RJ, Merrett ND, Toon C, Epari K, Nguyen NQ, Barbour A, Zeps N, Australian Pancreatic Cancer Genome Initiative, Kakkar N, Zhao F, Wu YQ, Wang M, Muzny DM, Fisher WE, Brunicardi FC, Hodges SE, Reid JG, Drummond J, Chang K, Han Y, Lewis LR, Dinh H, Buhay CJ, Beck T, Timms L, Sam M, Begley K, Brown A, Pai D, Panchal A, Buchner N, De Borja R, Denroche RE, Yung CK, Serra S, Onetto N, Mukhopadhyay D, Tsao MS, Shaw PA, Petersen GM, Gallinger S, Hruban RH, Maitra A, Iacobuzio-Donahue CA, Schulick RD, Wolfgang CL, Morgan RA, Lawlor RT, Capelli P, Corbo V, Scardoni M, Tortora G, Tempero MA, Mann KM, Jenkins NA, Perez-Mancera PA, Adams DJ, Largaespada DA, Wessels LF, Rust AG, Stein LD, Tuveson DA, Copeland NG, Musgrove EA, Scarpa A, Eshleman JR, Hudson TJ, Sutherland RL, Wheeler DA, Pearson JV, McPherson JD, Gibbs RA, Grimmond SM. PMID: 23103869; PMCID: PMC3530898.
      View in: PubMed   Mentions: 1188     Fields:    Translation:HumansAnimalsCells
    217. Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells. Proc Natl Acad Sci U S A. 2012 Oct 30; 109(44):E2998-3007. Koso H, Takeda H, Yew CC, Ward JM, Nariai N, Ueno K, Nagasaki M, Watanabe S, Rust AG, Adams DJ, Copeland NG, Jenkins NA. PMID: 23045694; PMCID: PMC3497753.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    218. Generation of the Sotos syndrome deletion in mice. Mamm Genome. 2012 Dec; 23(11-12):749-57. Migdalska AM, van der Weyden L, Ismail O, Sanger Mouse Genetics Project, Rust AG, Rashid M, White JK, Sánchez-Andrade G, Lupski JR, Logan DW, Arends MJ, Adams DJ. PMID: 22926222; PMCID: PMC3510424.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    219. Loss of RASSF1A synergizes with deregulated RUNX2 signaling in tumorigenesis. Cancer Res. 2012 Aug 01; 72(15):3817-3827. van der Weyden L, Papaspyropoulos A, Poulogiannis G, Rust AG, Rashid M, Adams DJ, Arends MJ, O'Neill E. PMID: 22710434; PMCID: PMC4067151.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    220. The genomic landscape shaped by selection on transposable elements across 18 mouse strains. Genome Biol. 2012 Jun 15; 13(6):R45. Nellåker C, Keane TM, Yalcin B, Wong K, Agam A, Belgard TG, Flint J, Adams DJ, Frankel WN, Ponting CP. PMID: 22703977; PMCID: PMC3446317.
      View in: PubMed   Mentions: 113     Fields:    Translation:AnimalsCells
    221. γ-Aminobutyric acid type B (GABAB) receptor expression is needed for inhibition of N-type (Cav2.2) calcium channels by analgesic α-conotoxins. J Biol Chem. 2012 Jul 06; 287(28):23948-57. Cuny H, de Faoite A, Huynh TG, Yasuda T, Berecki G, Adams DJ. PMID: 22613715; PMCID: PMC3390670.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    222. Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels. Biochem Pharmacol. 2012 Aug 15; 84(4):540-8. Vetter I, Dekan Z, Knapp O, Adams DJ, Alewood PF, Lewis RJ. PMID: 22609441.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    223. Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1. Mol Cancer. 2012 May 03; 11:29. van der Weyden L, Arends MJ, Rust AG, Poulogiannis G, McIntyre RE, Adams DJ. PMID: 22553910; PMCID: PMC3489691.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    224. Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (Ca(V) 2.2) calcium channels. Br J Pharmacol. 2012 May; 166(2):486-500. Adams DJ, Callaghan B, Berecki G. PMID: 22091786; PMCID: PMC3417482.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimals
    225. The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature. 2012 Apr 29; 486(7402):266-70. Pérez-Mancera PA, Rust AG, van der Weyden L, Kristiansen G, Li A, Sarver AL, Silverstein KA, Grützmann R, Aust D, Rümmele P, Knösel T, Herd C, Stemple DL, Kettleborough R, Brosnan JA, Li A, Morgan R, Knight S, Yu J, Stegeman S, Collier LS, ten Hoeve JJ, de Ridder J, Klein AP, Goggins M, Hruban RH, Chang DK, Biankin AV, Grimmond SM, Australian Pancreatic Cancer Genome Initiative, Wessels LF, Wood SA, Iacobuzio-Donahue CA, Pilarsky C, Largaespada DA, Adams DJ, Tuveson DA. PMID: 22699621; PMCID: PMC3376394.
      View in: PubMed   Mentions: 196     Fields:    Translation:HumansAnimalsCells
    226. Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation. EMBO J. 2012 May 30; 31(11):2486-97. Wilson CH, Crombie C, van der Weyden L, Poulogiannis G, Rust AG, Pardo M, Gracia T, Yu L, Choudhary J, Poulin GB, McIntyre RE, Winton DJ, March HN, Arends MJ, Fraser AG, Adams DJ. PMID: 22510880; PMCID: PMC3365428.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    227. An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model. Blood. 2012 May 10; 119(19):4512-23. Bergerson RJ, Collier LS, Sarver AL, Been RA, Lugthart S, Diers MD, Zuber J, Rappaport AR, Nixon MJ, Silverstein KA, Fan D, Lamblin AF, Wolff L, Kersey JH, Delwel R, Lowe SW, O'Sullivan MG, Kogan SC, Adams DJ, Largaespada DA. PMID: 22427200; PMCID: PMC3362364.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    228. Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. Proc Natl Acad Sci U S A. 2012 Apr 17; 109(16):5934-41. Mann KM, Ward JM, Yew CC, Kovochich A, Dawson DW, Black MA, Brett BT, Sheetz TE, Dupuy AJ, Australian Pancreatic Cancer Genome Initiative, Chang DK, Biankin AV, Waddell N, Kassahn KS, Grimmond SM, Rust AG, Adams DJ, Jenkins NA, Copeland NG. PMID: 22421440; PMCID: PMC3341075.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    229. Localization of Nav 1.7 in the normal and injured rodent olfactory system indicates a critical role in olfaction, pheromone sensing and immune function. Channels (Austin). 2012 Mar-Apr; 6(2):103-10. Rupasinghe DB, Knapp O, Blomster LV, Schmid AB, Adams DJ, King GF, Ruitenberg MJ. PMID: 22622154.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    230. The fine-scale architecture of structural variants in 17 mouse genomes. Genome Biol. 2012; 13(3):R18. Yalcin B, Wong K, Bhomra A, Goodson M, Keane TM, Adams DJ, Flint J. PMID: 22439878; PMCID: PMC3439969.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    231. RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs. Biochem Pharmacol. 2012 Feb 01; 83(3):419-26. Franco A, Kompella SN, Akondi KB, Melaun C, Daly NL, Luetje CW, Alewood PF, Craik DJ, Adams DJ, Marí F. PMID: 22108175.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    232. Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis. Nat Genet. 2011 Nov 06; 43(12):1202-9. March HN, Rust AG, Wright NA, ten Hoeve J, de Ridder J, Eldridge M, van der Weyden L, Berns A, Gadiot J, Uren A, Kemp R, Arends MJ, Wessels LF, Winton DJ, Adams DJ. PMID: 22057237; PMCID: PMC3233530.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    233. In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. Cell. 2011 Oct 14; 147(2):382-95. Karreth FA, Tay Y, Perna D, Ala U, Tan SM, Rust AG, DeNicola G, Webster KA, Weiss D, Perez-Mancera PA, Krauthammer M, Halaban R, Provero P, Adams DJ, Tuveson DA, Pandolfi PP. PMID: 22000016; PMCID: PMC3236086.
      View in: PubMed   Mentions: 382     Fields:    Translation:HumansAnimals
    234. Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor. J Med Chem. 2011 Oct 13; 54(19):6984-92. Halai R, Callaghan B, Daly NL, Clark RJ, Adams DJ, Craik DJ. PMID: 21888386.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    235. Computational identification of insertional mutagenesis targets for cancer gene discovery. Nucleic Acids Res. 2011 Aug; 39(15):e105. de Jong J, de Ridder J, van der Weyden L, Sun N, van Uitert M, Berns A, van Lohuizen M, Jonkers J, Adams DJ, Wessels LF. PMID: 21652642; PMCID: PMC3159484.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    236. Purification of immature neuronal cells from neural stem cell progeny. PLoS One. 2011; 6(6):e20941. Azari H, Osborne GW, Yasuda T, Golmohammadi MG, Rahman M, Deleyrolle LP, Esfandiari E, Adams DJ, Scheffler B, Steindler DA, Reynolds BA. PMID: 21687800; PMCID: PMC3109004.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    237. Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice. Blood. 2011 Jul 28; 118(4):1041-51. van der Weyden L, Giotopoulos G, Rust AG, Matheson LS, van Delft FW, Kong J, Corcoran AE, Greaves MF, Mullighan CG, Huntly BJ, Adams DJ. PMID: 21628403; PMCID: PMC3622520.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimals
    238. Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angew Chem Int Ed Engl. 2011 Jul 11; 50(29):6527-9. de Araujo AD, Callaghan B, Nevin ST, Daly NL, Craik DJ, Moretta M, Hopping G, Christie MJ, Adams DJ, Alewood PF. PMID: 21630402.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    239. Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function? J Biol Chem. 2011 Jun 24; 286(25):22546-57. Safavi-Hemami H, Siero WA, Kuang Z, Williamson NA, Karas JA, Page LR, MacMillan D, Callaghan B, Kompella SN, Adams DJ, Norton RS, Purcell AW. PMID: 21504902; PMCID: PMC3121399.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    240. Acute sensitivity of the oral mucosa to oncogenic K-ras. J Pathol. 2011 May; 224(1):22-32. van der Weyden L, Alcolea MP, Jones PH, Rust AG, Arends MJ, Adams DJ. PMID: 21381032; PMCID: PMC3627303.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    241. Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels. J Biol Chem. 2011 Mar 25; 286(12):10233-7. Daly NL, Callaghan B, Clark RJ, Nevin ST, Adams DJ, Craik DJ. PMID: 21252227; PMCID: PMC3060477.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    242. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature. 2011 Jan 27; 469(7331):539-42. Varela I, Tarpey P, Raine K, Huang D, Ong CK, Stephens P, Davies H, Jones D, Lin ML, Teague J, Bignell G, Butler A, Cho J, Dalgliesh GL, Galappaththige D, Greenman C, Hardy C, Jia M, Latimer C, Lau KW, Marshall J, McLaren S, Menzies A, Mudie L, Stebbings L, Largaespada DA, Wessels LF, Richard S, Kahnoski RJ, Anema J, Tuveson DA, Perez-Mancera PA, Mustonen V, Fischer A, Adams DJ, Rust A, Chan-on W, Subimerb C, Dykema K, Furge K, Campbell PJ, Teh BT, Stratton MR, Futreal PA. PMID: 21248752; PMCID: PMC3030920.
      View in: PubMed   Mentions: 695     Fields:    Translation:HumansAnimalsCells
    243. Regulation of voltage-gated ion channels in excitable cells by the ubiquitin ligases Nedd4 and Nedd4-2. Channels (Austin). 2011 Jan-Feb; 5(1):79-88. Bongiorno D, Schuetz F, Poronnik P, Adams DJ. PMID: 21057195.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    244. The engineering of an orally active conotoxin for the treatment of neuropathic pain. Angew Chem Int Ed Engl. 2010 Sep 03; 49(37):6545-8. Clark RJ, Jensen J, Nevin ST, Callaghan BP, Adams DJ, Craik DJ. PMID: 20533477.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimalsCells
    245. Stabilization of α-conotoxin AuIB: influences of disulfide connectivity and backbone cyclization. Antioxid Redox Signal. 2011 Jan 01; 14(1):87-95. Lovelace ES, Gunasekera S, Alvarmo C, Clark RJ, Nevin ST, Grishin AA, Adams DJ, Craik DJ, Daly NL. PMID: 20486767.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    246. Slingshot: a PiggyBac based transposon system for tamoxifen-inducible 'self-inactivating' insertional mutagenesis. Nucleic Acids Res. 2010 Oct; 38(18):e173. Kong J, Wang F, Brenton JD, Adams DJ. PMID: 20688953; PMCID: PMC2952874.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    247. Physiological roles of ion channels in adult neural stem cells and their progeny. J Neurochem. 2010 Aug; 114(4):946-59. Yasuda T, Adams DJ. PMID: 20492359.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    248. Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors. J Biol Chem. 2010 Jul 16; 285(29):22254-63. Grishin AA, Wang CI, Muttenthaler M, Alewood PF, Lewis RJ, Adams DJ. PMID: 20466726; PMCID: PMC2903359.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    249. Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. J Am Chem Soc. 2010 Mar 17; 132(10):3514-22. Muttenthaler M, Nevin ST, Grishin AA, Ngo ST, Choy PT, Daly NL, Hu SH, Armishaw CJ, Wang CI, Lewis RJ, Martin JL, Noakes PG, Craik DJ, Adams DJ, Alewood PF. PMID: 20163143.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    250. Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach. Cancer Res. 2010 Feb 01; 70(3):883-95. Mattison J, Kool J, Uren AG, de Ridder J, Wessels L, Jonkers J, Bignell GR, Butler A, Rust AG, Brosch M, Wilson CH, van der Weyden L, Largaespada DA, Stratton MR, Futreal PA, van Lohuizen M, Berns A, Collier LS, Hubbard T, Adams DJ. PMID: 20103622; PMCID: PMC2880710.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    251. Analgesic α-conotoxins Vc1.1 and RgIA inhibit N-type calcium channels in sensory neurons of α9 nicotinic receptor knockout mice. Channels (Austin). 2010 Jan-Feb; 4(1):51-4. Callaghan B, Adams DJ. PMID: 20368690.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    252. Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality. Cancer Res. 2009 Nov 01; 69(21):8429-37. Collier LS, Adams DJ, Hackett CS, Bendzick LE, Akagi K, Davies MN, Diers MD, Rodriguez FJ, Bender AM, Tieu C, Matise I, Dupuy AJ, Copeland NG, Jenkins NA, Hodgson JG, Weiss WA, Jenkins RB, Largaespada DA. PMID: 19843846; PMCID: PMC2771123.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    253. Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels. Genome Biol. 2009; 10(10):R112. Sudbery I, Stalker J, Simpson JT, Keane T, Rust AG, Hurles ME, Walter K, Lynch D, Teboul L, Brown SD, Li H, Ning Z, Nadeau JH, Croniger CM, Durbin R, Adams DJ. PMID: 19825173; PMCID: PMC2784327.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    254. Scanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptor. J Biol Chem. 2009 Jul 24; 284(30):20275-84. Halai R, Clark RJ, Nevin ST, Jensen JE, Adams DJ, Craik DJ. PMID: 19447885; PMCID: PMC2740453.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    255. A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites. Nat Protoc. 2009; 4(5):789-98. Uren AG, Mikkers H, Kool J, van der Weyden L, Lund AH, Wilson CH, Rance R, Jonkers J, van Lohuizen M, Berns A, Adams DJ. PMID: 19528954; PMCID: PMC3627465.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    256. Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3. Toxicon. 2009 Jul; 54(1):56-61. Jensen JE, Durek T, Alewood PF, Adams DJ, King GF, Rash LD. PMID: 19306891.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    257. Cancer gene discovery in mouse and man. Biochim Biophys Acta. 2009 Dec; 1796(2):140-61. Mattison J, van der Weyden L, Hubbard T, Adams DJ. PMID: 19285540; PMCID: PMC2756404.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    258. Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues. J Biol Chem. 2009 Feb 20; 284(8):4944-51. Millard EL, Nevin ST, Loughnan ML, Nicke A, Clark RJ, Alewood PF, Lewis RJ, Adams DJ, Craik DJ, Daly NL. PMID: 19098004.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    259. Analgesic alpha-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in rat sensory neurons via GABAB receptor activation. J Neurosci. 2008 Oct 22; 28(43):10943-51. Callaghan B, Haythornthwaite A, Berecki G, Clark RJ, Craik DJ, Adams DJ. PMID: 18945902; PMCID: PMC6671365.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    260. Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function. J Med Chem. 2008 Sep 25; 51(18):5575-84. Jin AH, Daly NL, Nevin ST, Wang CI, Dutertre S, Lewis RJ, Adams DJ, Craik DJ, Alewood PF. PMID: 18754612.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    261. omega-Conotoxin inhibition of excitatory synaptic transmission evoked by dorsal root stimulation in rat superficial dorsal horn. Neuropharmacology. 2008 Oct; 55(5):860-4. Motin L, Adams DJ. PMID: 18644398.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    262. Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels. J Biol Chem. 2008 Aug 01; 283(31):21621-8. Schroeder CI, Ekberg J, Nielsen KJ, Adams D, Loughnan ML, Thomas L, Adams DJ, Alewood PF, Lewis RJ. PMID: 18522941.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    263. Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks. Cell. 2008 May 16; 133(4):727-41. Uren AG, Kool J, Matentzoglu K, de Ridder J, Mattison J, van Uitert M, Lagcher W, Sie D, Tanger E, Cox T, Reinders M, Hubbard TJ, Rogers J, Jonkers J, Wessels L, Adams DJ, van Lohuizen M, Berns A. PMID: 18485879; PMCID: PMC2405818.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimalsCells
    264. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1. Am J Physiol Cell Physiol. 2008 Jul; 295(1):C73-80. Schuetz F, Kumar S, Poronnik P, Adams DJ. PMID: 18463232.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    265. The three-dimensional structure of the analgesic alpha-conotoxin, RgIA. FEBS Lett. 2008 Mar 05; 582(5):597-602. Clark RJ, Daly NL, Halai R, Nevin ST, Adams DJ, Craik DJ. PMID: 18242183.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    266. K(ir) and K(v) channels regulate electrical properties and proliferation of adult neural precursor cells. Mol Cell Neurosci. 2008 Feb; 37(2):284-97. Yasuda T, Bartlett PF, Adams DJ. PMID: 18023363.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    267. Polymodal regulation of NMDA receptor channels. Channels (Austin). 2007 Sep-Oct; 1(5):334-43. Kloda A, Martinac B, Adams DJ. PMID: 18690040.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    268. Renin enhancer is crucial for full response in Renin expression to an in vivo stimulus. Hypertension. 2007 Nov; 50(5):933-8. Markus MA, Goy C, Adams DJ, Lovicu FJ, Morris BJ. PMID: 17846348.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    269. Chemical modification of conotoxins to improve stability and activity. ACS Chem Biol. 2007 Jul 20; 2(7):457-68. Craik DJ, Adams DJ. PMID: 17649970.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    270. Purinergic receptor activation inhibits mitogen-stimulated proliferation in primary neurospheres from the adult mouse subventricular zone. Mol Cell Neurosci. 2007 Aug; 35(4):535-48. Stafford MR, Bartlett PF, Adams DJ. PMID: 17553694.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    271. Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics. BMC Struct Biol. 2007 Apr 20; 7:28. Jin AH, Brandstaetter H, Nevin ST, Tan CC, Clark RJ, Adams DJ, Alewood PF, Craik DJ, Daly NL. PMID: 17445276; PMCID: PMC1865545.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    272. The doublecortin-expressing population in the developing and adult brain contains multipotential precursors in addition to neuronal-lineage cells. J Neurosci. 2007 Apr 04; 27(14):3734-42. Walker TL, Yasuda T, Adams DJ, Bartlett PF. PMID: 17409237; PMCID: PMC6672401.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    273. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2. J Biol Chem. 2007 Apr 20; 282(16):12135-42. Ekberg J, Schuetz F, Boase NA, Conroy SJ, Manning J, Kumar S, Poronnik P, Adams DJ. PMID: 17322297.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    274. Liposome reconstitution and modulation of recombinant N-methyl-D-aspartate receptor channels by membrane stretch. Proc Natl Acad Sci U S A. 2007 Jan 30; 104(5):1540-5. Kloda A, Lua L, Hall R, Adams DJ, Martinac B. PMID: 17242368; PMCID: PMC1780071.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    275. Omega-conotoxin CVIB differentially inhibits native and recombinant N- and P/Q-type calcium channels. Eur J Neurosci. 2007 Jan; 25(2):435-44. Motin L, Yasuda T, Schroeder CI, Lewis RJ, Adams DJ. PMID: 17284184.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    276. Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels. Mol Pharmacol. 2007 Mar; 71(3):676-85. Lewis RJ, Schroeder CI, Ekberg J, Nielsen KJ, Loughnan M, Thomas L, Adams DA, Drinkwater R, Adams DJ, Alewood PF. PMID: 17142296.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    277. XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265. Nucleic Acids Res. 2006; 34(17):4976-86. Mangs AH, Speirs HJ, Goy C, Adams DJ, Markus MA, Morris BJ. PMID: 16982639; PMCID: PMC1635291.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    278. WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo. Exp Cell Res. 2006 Oct 15; 312(17):3379-88. Markus MA, Heinrich B, Raitskin O, Adams DJ, Mangs H, Goy C, Ladomery M, Sperling R, Stamm S, Morris BJ. PMID: 16934801.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    279. Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. J Biol Chem. 2006 Aug 25; 281(34):24745-55. Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, Alewood PF, Lewis RJ. PMID: 16790424.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    280. The synthesis, structural characterization, and receptor specificity of the alpha-conotoxin Vc1.1. J Biol Chem. 2006 Aug 11; 281(32):23254-63. Clark RJ, Fischer H, Nevin ST, Adams DJ, Craik DJ. PMID: 16754662.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    281. Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists. J Biol Chem. 2006 May 19; 281(20):14136-43. Armishaw CJ, Daly NL, Nevin ST, Adams DJ, Craik DJ, Alewood PF. PMID: 16500898.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    282. Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):13767-72. Clark RJ, Fischer H, Dempster L, Daly NL, Rosengren KJ, Nevin ST, Meunier FA, Adams DJ, Craik DJ. PMID: 16162671; PMCID: PMC1236553.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    283. Unusual findings in brain biopsies of two patients with acute magnetic resonance imaging lesions associated with focal seizures. Epilepsia. 2005 Sep; 46(9):1495-501. McClelland S, Libien JM, Chin SS, Adams DJ, Resor SR, Chan S, Goodman RR. PMID: 16146445.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    284. Tertiapin-Q blocks recombinant and native large conductance K+ channels in a use-dependent manner. J Pharmacol Exp Ther. 2005 Sep; 314(3):1353-61. Kanjhan R, Coulson EJ, Adams DJ, Bellingham MC. PMID: 15947038.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    285. Selective modulation of neuronal nicotinic acetylcholine receptor channel subunits by Go-protein subunits. J Neurosci. 2005 Apr 06; 25(14):3571-7. Fischer H, Liu DM, Lee A, Harries JC, Adams DJ. PMID: 15814787; PMCID: PMC6725378.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    286. Developmental changes in expression of GABAA receptor-channels in rat intrinsic cardiac ganglion neurones. J Physiol. 2005 Apr 15; 564(Pt 2):465-74. Fischer H, Harper AA, Anderson CR, Adams DJ. PMID: 15731187; PMCID: PMC1464452.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    287. Voltage-dependent inhibition of recombinant NMDA receptor-mediated currents by 5-hydroxytryptamine. Br J Pharmacol. 2005 Feb; 144(3):323-30. Kloda A, Adams DJ. PMID: 15655527; PMCID: PMC1576009.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    288. Intravenous anaesthetics inhibit nicotinic acetylcholine receptor-mediated currents and Ca2+ transients in rat intracardiac ganglion neurons. Br J Pharmacol. 2005 Jan; 144(1):98-107. Weber M, Motin L, Gaul S, Beker F, Fink RH, Adams DJ. PMID: 15644873; PMCID: PMC1575970.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    289. BRCTx is a novel, highly conserved RAD18-interacting protein. Mol Cell Biol. 2005 Jan; 25(2):779-88. Adams DJ, van der Weyden L, Gergely FV, Arends MJ, Ng BL, Tannahill D, Kanaar R, Markus A, Morris BJ, Bradley A. PMID: 15632077; PMCID: PMC543416.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    290. Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases. Chem Biol. 2005 Jan; 12(1):65-76. Rao FV, Houston DR, Boot RG, Aerts JM, Hodkinson M, Adams DJ, Shiomi K, Omura S, van Aalten DM. PMID: 15664516.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    291. Auxiliary subunit regulation of high-voltage activated calcium channels expressed in mammalian cells. Eur J Neurosci. 2004 Jul; 20(1):1-13. Yasuda T, Chen L, Barr W, McRory JE, Lewis RJ, Adams DJ, Zamponi GW. PMID: 15245474.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    292. Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-methyl-D-aspartate receptors. Mol Pharmacol. 2004 Jun; 65(6):1386-96. Kloda A, Clements JD, Lewis RJ, Adams DJ. PMID: 15155832.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    293. The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels. J Biol Chem. 2004 Aug 13; 279(33):34705-14. Mould J, Yasuda T, Schroeder CI, Beedle AM, Doering CJ, Zamponi GW, Adams DJ, Lewis RJ. PMID: 15166237.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    294. Potassium channels and membrane potential in the modulation of intracellular calcium in vascular endothelial cells. J Cardiovasc Electrophysiol. 2004 May; 15(5):598-610. Adams DJ, Hill MA. PMID: 15149433.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    295. Functional maturation of isolated neural progenitor cells from the adult rat hippocampus. Eur J Neurosci. 2004 May; 19(9):2410-20. Hogg RC, Chipperfield H, Whyte KA, Stafford MR, Hansen MA, Cool SM, Nurcombe V, Adams DJ. PMID: 15128395.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    296. Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2. J Biol Chem. 2004 Jul 09; 279(28):28930-5. Fotia AB, Ekberg J, Adams DJ, Cook DI, Poronnik P, Kumar S. PMID: 15123669.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    297. Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons. J Biol Chem. 2004 Jun 11; 279(24):25774-82. Daly NL, Ekberg JA, Thomas L, Adams DJ, Lewis RJ, Craik DJ. PMID: 15044438.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    298. Overexpressed Ca(v)beta3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of ultra-slow and closed-state inactivation. J Gen Physiol. 2004 Apr; 123(4):401-16. Yasuda T, Lewis RJ, Adams DJ. PMID: 15024042; PMCID: PMC2217459.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    299. Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. J Med Chem. 2004 Feb 26; 47(5):1234-41. Loughnan ML, Nicke A, Jones A, Adams DJ, Alewood PF, Lewis RJ. PMID: 14971903.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    300. HADHB, HuR, and CP1 bind to the distal 3'-untranslated region of human renin mRNA and differentially modulate renin expression. J Biol Chem. 2003 Nov 07; 278(45):44894-903. Adams DJ, Beveridge DJ, van der Weyden L, Mangs H, Leedman PJ, Morris BJ. PMID: 12933794.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    301. Inhibition of the norepinephrine transporter by the venom peptide chi-MrIA. Site of action, Na+ dependence, and structure-activity relationship. J Biol Chem. 2003 Oct 10; 278(41):40317-23. Sharpe IA, Palant E, Schroeder CI, Kaye DM, Adams DJ, Alewood PF, Lewis RJ. PMID: 12885787.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    302. Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA. J Biol Chem. 2003 Sep 05; 278(36):34451-7. Sharpe IA, Thomas L, Loughnan M, Motin L, Palant E, Croker DE, Alewood D, Chen S, Graham RM, Alewood PF, Adams DJ, Lewis RJ. PMID: 12824165.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    303. Muscarinic and nicotinic ACh receptor activation differentially mobilize Ca2+ in rat intracardiac ganglion neurons. J Neurophysiol. 2003 Sep; 90(3):1956-64. Beker F, Weber M, Fink RH, Adams DJ. PMID: 12761283.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    304. Alpha-conotoxins PnIA and [A10L]PnIA stabilize different states of the alpha7-L247T nicotinic acetylcholine receptor. J Biol Chem. 2003 Jul 18; 278(29):26908-14. Hogg RC, Hopping G, Alewood PF, Adams DJ, Bertrand D. PMID: 12746432.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    305. Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of alpha-conotoxin MII. J Med Chem. 2003 Mar 27; 46(7):1266-72. Blanchfield JT, Dutton JL, Hogg RC, Gallagher OP, Craik DJ, Jones A, Adams DJ, Lewis RJ, Alewood PF, Toth I. PMID: 12646037.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    306. The structure of the zinc finger domain from human splicing factor ZNF265 fold. J Biol Chem. 2003 Jun 20; 278(25):22805-11. Plambeck CA, Kwan AH, Adams DJ, Westman BJ, van der Weyden L, Medcalf RL, Morris BJ, Mackay JP. PMID: 12657633.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    307. Omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals. J Biol Chem. 2003 Feb 07; 278(6):4057-62. Adams DJ, Smith AB, Schroeder CI, Yasuda T, Lewis RJ. PMID: 12441339.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    308. Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence. J Biol Chem. 2003 Jan 31; 278(5):3137-44. Nicke A, Loughnan ML, Millard EL, Alewood PF, Adams DJ, Daly NL, Craik DJ, Lewis RJ. PMID: 12419800.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    309. A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity. J Biol Chem. 2002 Dec 13; 277(50):48849-57. Dutton JL, Bansal PS, Hogg RC, Adams DJ, Alewood PF, Craik DJ. PMID: 12376538.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    310. Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels. J Biol Chem. 2002 Jul 26; 277(30):27247-55. Nielsen KJ, Watson M, Adams DJ, Hammarström AK, Gage PW, Hill JM, Craik DJ, Thomas L, Adams D, Alewood PF, Lewis RJ. PMID: 12006587.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    311. Human non-pregnancy ribonuclease with anti-Kaposi's sarcoma activity. Cancer Lett. 2002 Feb 25; 176(2):183-9. Al-Owais MM, Hesse L, Talbot SJ, Adams DJ. PMID: 11804746.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    312. Association of a functional inducible nitric oxide synthase promoter variant with complications in type 2 diabetes. J Mol Med (Berl). 2002 Feb; 80(2):96-104. Morris BJ, Markus A, Glenn CL, Adams DJ, Colagiuri S, Wang L. PMID: 11907646.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
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