Michael A Lopez

Title(s)Assistant Health Sciences Professor, Neurology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(310) 794-3665
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A review of neurogenetics in fetal and neonatal clinical medicine. Semin Fetal Neonatal Med. 2024 Nov 07; 101550. Ananth AL, Lopez MA. PMID: 39551661.
      View in: PubMed   Mentions:
    2. Long-read genome sequencing and variant reanalysis increase diagnostic yield in neurodevelopmental disorders. Genome Res. 2024 Sep 19. Hiatt SM, Lawlor JM, Handley LH, Latner DR, Bonnstetter ZT, Finnila CR, Thompson ML, Boston LB, Williams M, Rodriguez-Nunez I, Jenkins J, Kelley WV, Bebin EM, Lopez MA, Hurst AC, Korf BR, Schmutz J, Grimwood J, Cooper GM. PMID: 39299904.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. ANKRD1 expression is aberrantly upregulated in the mdm mouse model of muscular dystrophy and induced by stretch through NFκB. J Muscle Res Cell Motil. 2024 Dec; 45(4):191-200. Lopez MA, Pardo PS, Mohamed JS, Boriek AM. PMID: 38683293.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Late-Stage Skeletal Muscle Transcriptome in Duchenne muscular dystrophy shows a BMP4-Induced Molecular Signature. bioRxiv. 2024 Apr 25. Sothers H, Hu X, Crossman DK, Si Y, Alexander MS, McDonald MN, King PH, Lopez MA. PMID: 38712206; PMCID: PMC11071434.
      View in: PubMed   Mentions:
    5. Long-read genome sequencing and variant reanalysis increase diagnostic yield in neurodevelopmental disorders. medRxiv. 2024 Mar 26. Hiatt SM, Lawlor JMJ, Handley LH, Latner DR, Bonnstetter ZT, Finnila CR, Thompson ML, Boston LB, Williams M, Nunez IR, Jenkins J, Kelley WV, Bebin EM, Lopez MA, Hurst ACE, Korf BR, Schmutz J, Grimwood J, Cooper GM. PMID: 38585854; PMCID: PMC10996728.
      View in: PubMed   Mentions:
    6. Cooperative CAR targeting to selectively eliminate AML and minimize escape. Cancer Cell. 2023 11 13; 41(11):1871-1891.e6. Haubner S, Mansilla-Soto J, Nataraj S, Kogel F, Chang Q, de Stanchina E, Lopez M, Ng MR, Fraser K, Subklewe M, Park JH, Wang X, Rivière I, Sadelain M. PMID: 37802054; PMCID: PMC11006543.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    7. Del1 Is a Growth Factor for Skeletal Progenitor Cells in the Fracture Callus. Biomolecules. 2023 08 03; 13(8). Sun Y, Boyko T, Marecic O, Struck D, Mann RK, Andrew TW, Lopez M, Tong X, Goodman SB, Yang F, Longaker MT, Chan CKF, Yang GP. PMID: 37627279; PMCID: PMC10452420.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    8. TET2 guards against unchecked BATF3-induced CAR T cell expansion. Nature. 2023 03; 615(7951):315-322. Jain N, Zhao Z, Feucht J, Koche R, Iyer A, Dobrin A, Mansilla-Soto J, Yang J, Zhan Y, Lopez M, Gunset G, Sadelain M. PMID: 36755094; PMCID: PMC10511001.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    9. In-depth analysis of alternative splicing landscape in multiple myeloma and potential role of dysregulated splicing factors. Blood Cancer J. 2022 12 20; 12(12):171. Aktas Samur A, Fulciniti M, Avet-Loiseau H, Lopez MA, Derebail S, Corre J, Minvielle S, Magrangeas F, Moreau P, Anderson KC, Parmigiani G, Samur MK, Munshi NC. PMID: 36535935; PMCID: PMC9763261.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    10. Smad8 Is Increased in Duchenne Muscular Dystrophy and Suppresses miR-1, miR-133a, and miR-133b. Int J Mol Sci. 2022 Jul 07; 23(14). Lopez MA, Si Y, Hu X, Williams V, Qushair F, Carlyle J, Alesce L, Conklin M, Gilbert S, Bamman MM, Alexander MS, King PH. PMID: 35886863; PMCID: PMC9323105.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    11. Pediatric Nemaline Myopathy: A Systematic Review Using Individual Patient Data. J Child Neurol. 2022 06; 37(7):652-663. Christophers B, Lopez MA, Gupta VA, Vogel H, Baylies M. PMID: 36960434; PMCID: PMC10032635.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    12. DOCKopathies: A systematic review of the clinical pathologies associated with human DOCK pathogenic variants. Hum Mutat. 2022 09; 43(9):1149-1161. Samani A, English KG, Lopez MA, Birch CL, Brown DM, Kaur G, Worthey EA, Alexander MS. PMID: 35544951; PMCID: PMC9357139.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    13. miR-486 is essential for muscle function and suppresses a dystrophic transcriptome. Life Sci Alliance. 2022 09; 5(9). Samani A, Hightower RM, Reid AL, English KG, Lopez MA, Doyle JS, Conklin MJ, Schneider DA, Bamman MM, Widrick JJ, Crossman DK, Xie M, Jee D, Lai EC, Alexander MS. PMID: 35512829; PMCID: PMC9087951.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    14. Robotic Resection of Pulmonary Epithelial Myoepithelial Carcinoma: A Case Report. Thorac Cardiovasc Surg Rep. 2021 Jan; 10(1):e42-e44. Jindani R, Lopez MA, Miquel TP, Sylvin E. PMID: 34194921; PMCID: PMC8236324.
      View in: PubMed   Mentions:
    15. Mechanics of dystrophin deficient skeletal muscles in very young mice and effects of age. Am J Physiol Cell Physiol. 2021 08 01; 321(2):C230-C246. Lopez MA, Bontiff S, Adeyeye M, Shaibani AI, Alexander MS, Wynd S, Boriek AM. PMID: 33979214; PMCID: PMC8424675.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    16. Pediatric Autoimmune Ocular Myasthenia Gravis: Evaluation of Presentation and Treatment Outcomes in a Large Cohort. Pediatr Neurol. 2021 05; 118:12-19. Fisher KS, Gill J, Todd HF, Yang MB, Lopez MA, Abid F, Lotze T, Shah VS. PMID: 33684630.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Clinical exome sequencing in the diagnosis of pediatric neuromuscular disease. Muscle Nerve. 2021 03; 63(3):304-310. Herman I, Lopez MA, Marafi D, Pehlivan D, Calame DG, Abid F, Lotze TE. PMID: 33146414.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    18. DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies. Hum Mol Genet. 2020 10 10; 29(17):2855-2871. Reid AL, Wang Y, Samani A, Hightower RM, Lopez MA, Gilbert SR, Ianov L, Crossman DK, Dell'Italia LJ, Millay DP, van Groen T, Halade GV, Alexander MS. PMID: 32766788; PMCID: PMC7566544.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    19. Hospital Readmissions for Hyperparathyroidism After Bariatric Surgery in the United States: A National Database Review. Cureus. 2020 Sep 22; 12(9):e10585. Qafiti FN, Lopez MA, Kichler K, Parreco J, Buicko JL. PMID: 33110721; PMCID: PMC7580962.
      View in: PubMed   Mentions:
    20. YWHAE/14-3-3ε expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma. Blood. 2020 07 23; 136(4):468-479. Xu Y, Fulciniti M, Samur MK, Ho M, Deng S, Liu L, Wen K, Yu T, Chyra Z, Dereibal S, Zhang L, Yao Y, Chakraborty C, Morelli E, Li N, Lopez MA, Perini T, Mu S, An G, Alonso R, Bianchi G, Tai YT, Anderson KC, Qiu L, Munshi NC. PMID: 32187357; PMCID: PMC7378455.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    21. Fibulin-5 mutation featuring Charcot-Marie-Tooth disease, joint hyperlaxity, and scoliosis. Neurol Genet. 2020 Aug; 6(4):e476. Kazamel M, Lopez MA, Bebin M, Bowling K, Korf BR, Barsh GS, Cooper GM, Hurst ACE, Ubogu EE. PMID: 32802946; PMCID: PMC7413605.
      View in: PubMed   Mentions:
    22. Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma. Cell Rep. 2018 12 26; 25(13):3693-3705.e6. Fulciniti M, Lin CY, Samur MK, Lopez MA, Singh I, Lawlor MA, Szalat RE, Ott CJ, Avet-Loiseau H, Anderson KC, Young RA, Bradner JE, Munshi NC. PMID: 30590042; PMCID: PMC6407615.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    23. Dual PAK4-NAMPT Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldenström Macroglobulinemia. Clin Cancer Res. 2019 01 01; 25(1):369-377. Li N, Lopez MA, Linares M, Kumar S, Oliva S, Martinez-Lopez J, Xu L, Xu Y, Perini T, Senapedis W, Baloglu E, Shammas MA, Hunter Z, Anderson KC, Treon SP, Munshi NC, Fulciniti M. PMID: 30206161; PMCID: PMC6320280.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    24. Nationally Representative Readmission Factors in Patients with Claudication and Critical Limb Ischemia. Ann Vasc Surg. 2018 Oct; 52:96-107. Martinez RA, Shnayder M, Parreco J, Gaffney L, Eby M, Cortolillo N, Lopez M, Zeltzer J. PMID: 29777842.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. Antigen-mediated regulation in monoclonal gammopathies and myeloma. JCI Insight. 2018 04 19; 3(8). Nair S, Sng J, Boddupalli CS, Seckinger A, Chesi M, Fulciniti M, Zhang L, Rauniyar N, Lopez M, Neparidze N, Parker T, Munshi NC, Sexton R, Barlogie B, Orlowski R, Bergsagel L, Hose D, Flavell RA, Mistry PK, Meffre E, Dhodapkar MV. PMID: 29669929; PMCID: PMC5931125.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    26. Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma. Nat Genet. 2018 04; 50(4):515-523. Zeid R, Lawlor MA, Poon E, Reyes JM, Fulciniti M, Lopez MA, Scott TG, Nabet B, Erb MA, Winter GE, Jacobson Z, Polaski DR, Karlin KL, Hirsch RA, Munshi NP, Westbrook TF, Chesler L, Lin CY, Bradner JE. PMID: 29379199; PMCID: PMC6310397.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansCells
    27. Thirty-day readmissions following parathyroidectomy: Evidence from the National Readmissions Database, 2013-2014. Am J Otolaryngol. 2018 Mar - Apr; 39(2):82-87. Kravietz AM, Buicko JL, Parreco JP, Lopez MA, Kozol RA. PMID: 29352596.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    28. Anisotropic mechanosensitive pathways in the diaphragm and their implications in muscular dystrophies. J Muscle Res Cell Motil. 2017 12; 38(5-6):437-446. Pardo PS, Lopez MA, Mohamed JS, Boriek AM. PMID: 28986699.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    29. Obesity modulates diaphragm curvature in subjects with and without COPD. Am J Physiol Regul Integr Comp Physiol. 2017 Nov 01; 313(5):R620-R629. Boriek AM, Lopez MA, Velasco C, Bakir AA, Frolov A, Wynd S, Babb TG, Hanania NA, Hoffman EA, Sharafkhaneh A. PMID: 28903915; PMCID: PMC5792148.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    30. Dependence of Elevated Eosinophil Levels on Geographic Location in the VA San Diego Healthcare System. Fed Pract. 2017 May; 34(5):28-33. Mir Syed RR, Lopez MA, Thomas C, Clopton P, Smith DM, Jagasia P. PMID: 30766278; PMCID: PMC6370435.
      View in: PubMed   Mentions:
    31. Pediatric laparoscopic appendectomy, risk factors, and costs associated with nationwide readmissions. J Surg Res. 2017 07; 215:245-249. Buicko JL, Parreco J, Abel SN, Lopez MA, Sola JE, Perez EA. PMID: 28688655.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    32. Primary Amebic Meningoencephalitis in Children: A Report of Two Fatal Cases and Review of the Literature. Pediatr Neurol. 2017 05; 70:75-79. Stowe RC, Pehlivan D, Friederich KE, Lopez MA, DiCarlo SM, Boerwinkle VL. PMID: 28389055.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    33. Characterizing the operative findings and utility of intraoperative parathyroid hormone (IOPTH) monitoring in patients with normal baseline IOPTH and normohormonal primary hyperparathyroidism. Surgery. 2017 01; 161(1):78-86. Trinh G, Noureldine SI, Russell JO, Agrawal N, Lopez M, Prescott JD, Zeiger MA, Tufano RP. PMID: 27863787.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. Angiostrongylus cantonensis Infection: A Cause of Fever of Unknown Origin in Pediatric Patients. Clin Infect Dis. 2016 Dec 01; 63(11):1475-1478. Foster CE, Nicholson EG, Chun AC, Gharfeh M, Anvari S, Seeborg FO, Lopez MA, Campbell JR, Marquez L, Starke JR, Palazzi DL. PMID: 27578821.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    35. Genome-wide Mechanosensitive MicroRNA (MechanomiR) Screen Uncovers Dysregulation of Their Regulatory Networks in the mdm Mouse Model of Muscular Dystrophy. J Biol Chem. 2015 Oct 09; 290(41):24986-5011. Mohamed JS, Hajira A, Lopez MA, Boriek AM. PMID: 26272747; PMCID: PMC4599005.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    36. Early predictors of hypocalcemia after total thyroidectomy: an analysis of 304 patients using a short-stay monitoring protocol. JAMA Otolaryngol Head Neck Surg. 2014 Nov; 140(11):1006-13. Noureldine SI, Genther DJ, Lopez M, Agrawal N, Tufano RP. PMID: 25321339; PMCID: PMC4316663.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    37. Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction. J Biol Chem. 2013 Aug 23; 288(34):24560-8. Mohamed JS, Lopez MA, Cox GA, Boriek AM. PMID: 23824195; PMCID: PMC3750154.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    38. Acute abdominal pain secondary to chilaiditi syndrome. Case Rep Surg. 2013; 2013:756590. Kang D, Pan AS, Lopez MA, Buicko JL, Lopez-Viego M. PMID: 23936720; PMCID: PMC3713330.
      View in: PubMed   Mentions: 19  
    39. Novel deletion of lysine 7 expands the clinical, histopathological and genetic spectrum of TPM2-related myopathies. Brain. 2013 Feb; 136(Pt 2):508-21. Davidson AE, Siddiqui FM, Lopez MA, Lunt P, Carlson HA, Moore BE, Love S, Born DE, Roper H, Majumdar A, Jayadev S, Underhill HR, Smith CO, von der Hagen M, Hubner A, Jardine P, Merrison A, Curtis E, Cullup T, Jungbluth H, Cox MO, Winder TL, Abdel Salam H, Li JZ, Moore SA, Dowling JJ. PMID: 23413262; PMCID: PMC3572924.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    40. The therapeutic profile of rolipram, PDE target and mechanism of action as a neuroprotectant following spinal cord injury. PLoS One. 2012; 7(9):e43634. Schaal SM, Garg MS, Ghosh M, Lovera L, Lopez M, Patel M, Louro J, Patel S, Tuesta L, Chan WM, Pearse DD. PMID: 23028463; PMCID: PMC3446989.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    41. Induction of Sirt1 by mechanical stretch of skeletal muscle through the early response factor EGR1 triggers an antioxidative response. J Biol Chem. 2011 Jan 28; 286(4):2559-66. Pardo PS, Mohamed JS, Lopez MA, Boriek AM. PMID: 20971845; PMCID: PMC3024751.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    42. Diaphragm muscle shortening modulates kinematics of lower rib cage in dogs. Am J Physiol Regul Integr Comp Physiol. 2010 Dec; 299(6):R1456-62. Chu I, Fernandez C, Rodowicz KA, Lopez MA, Lu R, Hubmayr RD, Boriek AM. PMID: 20739605; PMCID: PMC3007179.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    43. Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3β. J Biol Chem. 2010 Sep 17; 285(38):29336-47. Mohamed JS, Lopez MA, Boriek AM. PMID: 20525681; PMCID: PMC2937966.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansCells
    44. Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch. FASEB J. 2010 Sep; 24(9):3330-40. Mohamed JS, Lopez MA, Cox GA, Boriek AM. PMID: 20442316; PMCID: PMC2923360.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    45. Early mechanical dysfunction of the diaphragm in the muscular dystrophy with myositis (Ttnmdm) model. Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1092-102. Lopez MA, Pardo PS, Cox GA, Boriek AM. PMID: 18753318; PMCID: PMC2584999.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    46. FOXO transcription factors are mechanosensitive and their regulation is altered with aging in the respiratory pump. Am J Physiol Cell Physiol. 2008 Apr; 294(4):C1056-66. Pardo PS, Lopez MA, Boriek AM. PMID: 18272820.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
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