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Gain-of-Function Engineering of the NifEN Scaffold Into a Self-Assembling Nitrogenase. Angew Chem Int Ed Engl. 2026 Sep 21; e8683437.
Yang Y, Lee CC, Ortiz S, Ribbe MW, Hu Y. PMID: 42766339.
View in:
PubMed Mentions:
-
Minimal ATP-Independent N2-Reducing Systems Defined by L-Cluster-Bound Nitrogenase Assembly Platforms. Angew Chem Int Ed Engl. 2026 06 08; 65(24):e2968123.
Quechol R, Yang Y, Lee CC, Ribbe MW, Hu Y. PMID: 42046444; PMCID: PMC13245594.
View in:
PubMed Mentions: Fields:
Translation:
Cells
-
Structural insights into metallocluster trafficking in the nitrogenase assembly scaffold NifEN. Nat Catal. 2026; 9(3):281-294.
Neumann B, Brandon KA, Quechol R, Suder DS, Lee CC, Yang Y, Górecki K, Wiig JA, Hu Y, Gonen S, Ribbe MW. PMID: 41908675; PMCID: PMC13031127.
View in:
PubMed Mentions:
-
Dual-enzyme logic powers azetidine biosynthesis. Nat Chem. 2026 Mar; 18(3):438-440.
Ribbe MW, Hu Y. PMID: 41741672.
View in:
PubMed Mentions: Fields:
-
Crossing Enzymatic Boundaries by Coupling BchNB with the Nitrogenase Cofactor Precursor. Chembiochem. 2026 Jan; 27(1):e202500923.
Lee CC, Yang Y, Górecki K, Hu Y, Ribbe MW. PMID: 41517965.
View in:
PubMed Mentions: Fields:
Translation:
Cells
-
Reductant- or Light-Driven ATP-Independent Reduction of CO2 by Nitrogenase MoFe Protein. Chembiochem. 2025 Sep 12; 26(16):e202500366.
Lee CC, Hu Y, Ribbe MW. PMID: 40523157; PMCID: PMC12292853.
View in:
PubMed Mentions: Fields:
Translation:
Cells
-
Heterologous synthesis of a simplified nitrogenase analog in Escherichia coli. Sci Adv. 2025 May 02; 11(18):eadw6785.
Liu YA, Lee CC, Górecki K, Stiebritz MT, Duffin C, Solomon JB, Ribbe MW, Hu Y. PMID: 40315313; PMCID: PMC12047441.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
-
Belt-Sulfur Mobilization as a Crucial Mechanistic Feature Shared between the Vanadium and Molybdenum Nitrogenases. Chem Catal. 2025 Jul 17; 5(7).
Lee CC, Chatterjee K, Yano J, Kern J, Stiebritz MT, Ribbe MW, Hu Y. PMID: 40708566; PMCID: PMC12285644.
View in:
PubMed Mentions:
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Ammonia synthesis via an engineered nitrogenase assembly pathway in Escherichia coli. Nat Catal. 2024 Oct; 7(10):1130-1141.
Solomon JB, Lee CC, Liu YA, Duffin C, Ribbe MW, Hu Y. PMID: 39713742; PMCID: PMC11661828.
View in:
PubMed Mentions:
7
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Cofactor maturase NifEN: A prototype ancient nitrogenase? Sci Adv. 2024 06 14; 10(24):eado6169.
Lee CC, Górecki K, Stang M, Ribbe MW, Hu Y. PMID: 38865457; PMCID: PMC11168457.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
-
Reactivity, Mechanism, and Assembly of the Alternative Nitrogenases. Chem Rev. 2020 06 24; 120(12):5107-5157.
Jasniewski AJ, Lee CC, Ribbe MW, Hu Y. PMID: 32129988; PMCID: PMC7491575.
View in:
PubMed Mentions:
82 Fields:
Translation:
Cells
-
Heterologous Expression and Engineering of the Nitrogenase Cofactor Biosynthesis Scaffold NifEN. Angew Chem Int Ed Engl. 2020 04 20; 59(17):6887-6893.
Solomon JB, Lee CC, Jasniewski AJ, Rasekh MF, Ribbe MW, Hu Y. PMID: 32022452.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
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Electron Paramagnetic Resonance and Magnetic Circular Dichroism Spectra of the Nitrogenase M Cluster Precursor Suggest Sulfur Migration upon Oxidation: A Proposal for Substrate and Inhibitor Binding. Chembiochem. 2020 06 15; 21(12):1767-1772.
Rupnik K, Tanifuji K, Rettberg L, Ribbe MW, Hu Y, Hales BJ. PMID: 31881119; PMCID: PMC7481019.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
A V-Nitrogenase Variant Containing a Citrate-Substituted Cofactor. Chembiochem. 2020 06 15; 21(12):1742-1748.
Newcomb MP, Lee CC, Tanifuji K, Jasniewski AJ, Liedtke J, Ribbe MW, Hu Y. PMID: 31747483.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
-
Electrochemical Characterization of Isolated Nitrogenase Cofactors from Azotobacter vinelandii. Chembiochem. 2020 06 15; 21(12):1773-1778.
Lydon BR, Lee CC, Tanifuji K, Sickerman NS, Newcomb MP, Hu Y, Ribbe MW, Yang JY. PMID: 31392810.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Spectroscopic Characterization of an Eight-Iron Nitrogenase Cofactor Precursor that Lacks the "9th Sulfur". Angew Chem Int Ed Engl. 2019 10 07; 58(41):14703-14707.
Jasniewski AJ, Wilcoxen J, Tanifuji K, Hedman B, Hodgson KO, Britt RD, Hu Y, Ribbe MW. PMID: 31411369; PMCID: PMC6764854.
View in:
PubMed Mentions:
16 Fields:
Translation:
Cells
-
Structural and Mechanistic Insights into CO2 Activation by Nitrogenase Iron Protein. Chemistry. 2019 Oct 11; 25(57):13078-13082.
Rettberg LA, Stiebritz MT, Kang W, Lee CC, Ribbe MW, Hu Y. PMID: 31402524.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
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Structural Analysis of a Nitrogenase Iron Protein from Methanosarcina acetivorans: Implications for CO2 Capture by a Surface-Exposed [Fe4S4] Cluster. mBio. 2019 07 09; 10(4).
Rettberg LA, Kang W, Stiebritz MT, Hiller CJ, Lee CC, Liedtke J, Ribbe MW, Hu Y. PMID: 31289188; PMCID: PMC6747716.
View in:
PubMed Mentions:
9 Fields:
Translation:
Cells
-
Purification of Nitrogenase Proteins. Methods Mol Biol. 2019; 1876:111-124.
Lee CC, Ribbe MW, Hu Y. PMID: 30317477.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
-
Electron Paramagnetic Resonance Spectroscopy of Metalloproteins. Methods Mol Biol. 2019; 1876:197-211.
Jasniewski A, Hu Y, Ribbe MW. PMID: 30317483.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
-
Nitrogenases. Methods Mol Biol. 2019; 1876:3-24.
Sickerman NS, Hu Y, Ribbe MW. PMID: 30317471.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
-
Reduction and Condensation of Aldehydes by the Isolated Cofactor of Nitrogenase. ACS Cent Sci. 2018 Oct 24; 4(10):1430-1435.
Lee CC, Hu Y, Ribbe MW. PMID: 30410981; PMCID: PMC6202647.
View in:
PubMed Mentions:
6
-
Radical S-Adenosyl-l-Methionine (SAM) Enzyme Involved in the Maturation of the Nitrogenase Cluster. Methods Enzymol. 2018; 606:341-361.
Rettberg L, Tanifuji K, Jasniewski A, Ribbe MW, Hu Y. PMID: 30097098.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
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Tracing the 'ninth sulfur' of the nitrogenase cofactor via a semi-synthetic approach. Nat Chem. 2018 05; 10(5):568-572.
Tanifuji K, Lee CC, Sickerman NS, Tatsumi K, Ohki Y, Hu Y, Ribbe MW. PMID: 29662207; PMCID: PMC5910187.
View in:
PubMed Mentions:
31 Fields:
Translation:
Cells
-
A VTVH MCD and EPR Spectroscopic Study of the Maturation of the "Second" Nitrogenase P-Cluster. Inorg Chem. 2018 Apr 16; 57(8):4719-4725.
Rupnik K, Lee CC, Hu Y, Ribbe MW, Hales BJ. PMID: 29611695; PMCID: PMC6249136.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
-
Characterization of an M-Cluster-Substituted Nitrogenase VFe Protein. mBio. 2018 03 13; 9(2).
Rebelein JG, Lee CC, Newcomb M, Hu Y, Ribbe MW. PMID: 29535200; PMCID: PMC5850330.
View in:
PubMed Mentions:
13 Fields:
Translation:
Cells
-
A Comparative Analysis of the CO-Reducing Activities of MoFe Proteins Containing Mo- and V-Nitrogenase Cofactors. Chembiochem. 2018 04 04; 19(7):649-653.
Lee CC, Tanifuji K, Newcomb M, Liedtke J, Hu Y, Ribbe MW. PMID: 29363247.
View in:
PubMed Mentions:
16 Fields:
Translation:
Cells
-
Nitrogenase Cofactor Assembly: An Elemental Inventory. Acc Chem Res. 2017 11 21; 50(11):2834-2841.
Sickerman NS, Ribbe MW, Hu Y. PMID: 29064664.
View in:
PubMed Mentions:
13 Fields:
-
Nitrogenase Assembly: Strategies and Procedures. Methods Enzymol. 2017; 595:261-302.
Sickerman NS, Hu Y, Ribbe MW. PMID: 28882203.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
-
Synthetic Analogues of Nitrogenase Metallocofactors: Challenges and Developments. Chemistry. 2017 Sep 12; 23(51):12425-12432.
Sickerman NS, Tanifuji K, Hu Y, Ribbe MW. PMID: 28726330.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
-
Activation of CO2 by Vanadium Nitrogenase. Chem Asian J. 2017 Aug 17; 12(16):1985-1996.
Sickerman NS, Hu Y, Ribbe MW. PMID: 28544649.
View in:
PubMed Mentions:
5 Fields:
-
Cluster assembly in nitrogenase. Essays Biochem. 2017 05 09; 61(2):271-279.
Sickerman NS, Rettberg LA, Lee CC, Hu Y, Ribbe MW. PMID: 28487403.
View in:
PubMed Mentions:
12 Fields:
-
Reduction of C1 Substrates to Hydrocarbons by the Homometallic Precursor and Synthetic Mimic of the Nitrogenase Cofactor. J Am Chem Soc. 2017 01 18; 139(2):603-606.
Sickerman NS, Tanifuji K, Lee CC, Ohki Y, Tatsumi K, Ribbe MW, Hu Y. PMID: 28043123.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
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The in vivo hydrocarbon formation by vanadium nitrogenase follows a secondary metabolic pathway. Nat Commun. 2016 12 15; 7:13641.
Rebelein JG, Lee CC, Hu Y, Ribbe MW. PMID: 27976719; PMCID: PMC5172229.
View in:
PubMed Mentions:
13 Fields:
Translation:
Cells
-
Structure and Reactivity of an Asymmetric Synthetic Mimic of Nitrogenase Cofactor. Angew Chem Int Ed Engl. 2016 12 12; 55(50):15633-15636.
Tanifuji K, Sickerman N, Lee CC, Nagasawa T, Miyazaki K, Ohki Y, Tatsumi K, Hu Y, Ribbe MW. PMID: 27862765.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
-
Assembly scaffold NifEN: A structural and functional homolog of the nitrogenase catalytic component. Proc Natl Acad Sci U S A. 2016 08 23; 113(34):9504-8.
Fay AW, Blank MA, Rebelein JG, Lee CC, Ribbe MW, Hedman B, Hodgson KO, Hu Y. PMID: 27506795; PMCID: PMC5003292.
View in:
PubMed Mentions:
13 Fields:
Translation:
Cells
-
Nitrogenases-A Tale of Carbon Atom(s). Angew Chem Int Ed Engl. 2016 07 11; 55(29):8216-26.
Hu Y, Ribbe MW. PMID: 27206025.
View in:
PubMed Mentions:
22 Fields:
-
Maturation of nitrogenase cofactor-the role of a class E radical SAM methyltransferase NifB. Curr Opin Chem Biol. 2016 04; 31:188-94.
Hu Y, Ribbe MW. PMID: 26969410; PMCID: PMC4870152.
View in:
PubMed Mentions:
14 Fields:
Translation:
Cells
-
YedY: A Mononuclear Molybdenum Enzyme with a Redox-Active Ligand? Chembiochem. 2016 Mar 15; 17(6):453-5.
Lee CC, Sickerman NS, Hu Y, Ribbe MW. PMID: 26751730; PMCID: PMC4922886.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Biosynthesis of the Metalloclusters of Nitrogenases. Annu Rev Biochem. 2016 Jun 02; 85:455-83.
Hu Y, Ribbe MW. PMID: 26844394.
View in:
PubMed Mentions:
45 Fields:
Translation:
Cells
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Uncoupling binding of substrate CO from turnover by vanadium nitrogenase. Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45):13845-9.
Lee CC, Fay AW, Weng TC, Krest CM, Hedman B, Hodgson KO, Hu Y, Ribbe MW. PMID: 26515097; PMCID: PMC4653198.
View in:
PubMed Mentions:
17 Fields:
-
Combining a Nitrogenase Scaffold and a Synthetic Compound into an Artificial Enzyme. Angew Chem Int Ed Engl. 2015 Nov 16; 54(47):14022-5.
Tanifuji K, Lee CC, Ohki Y, Tatsumi K, Hu Y, Ribbe MW. PMID: 26473503; PMCID: PMC4715667.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
-
Refining the pathway of carbide insertion into the nitrogenase M-cluster. Nat Commun. 2015 Aug 11; 6:8034.
Wiig JA, Hu Y, Ribbe MW. PMID: 26259825; PMCID: PMC4535184.
View in:
PubMed Mentions:
31 Fields:
Translation:
Cells
-
Widening the Product Profile of Carbon Dioxide Reduction by Vanadium Nitrogenase. Chembiochem. 2015 Sep 21; 16(14):1993-6.
Rebelein JG, Hu Y, Ribbe MW. PMID: 26266490; PMCID: PMC4696554.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
-
Insights into the Mechanism of Carbon Monoxide Dehydrogenase at Atomic Resolution. Angew Chem Int Ed Engl. 2015 Jul 13; 54(29):8337-9.
Ribbe MW. PMID: 26031600.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
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Insights into hydrocarbon formation by nitrogenase cofactor homologs. mBio. 2015 Apr 14; 6(2).
Lee CC, Hu Y, Ribbe MW. PMID: 25873377; PMCID: PMC4453561.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
-
Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases. Biochem J. 2015 Jun 15; 468(3):475-84.
Cahn JK, Brinkmann-Chen S, Spatzal T, Wiig JA, Buller AR, Einsle O, Hu Y, Ribbe MW, Arnold FH. PMID: 25849365; PMCID: PMC4550535.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
-
Nitrogenase and homologs. J Biol Inorg Chem. 2015 Mar; 20(2):435-45.
Hu Y, Ribbe MW. PMID: 25491285; PMCID: PMC4336585.
View in:
PubMed Mentions:
42 Fields:
Translation:
Cells
-
Catalytic reduction of CN-, CO, and CO2 by nitrogenase cofactors in lanthanide-driven reactions. Angew Chem Int Ed Engl. 2015 Jan 19; 54(4):1219-22.
Lee CC, Hu Y, Ribbe MW. PMID: 25420957; PMCID: PMC4300254.
View in:
PubMed Mentions:
26 Fields:
Translation:
Cells
-
Differential reduction of CO₂ by molybdenum and vanadium nitrogenases. Angew Chem Int Ed Engl. 2014 Oct 20; 53(43):11543-6.
Rebelein JG, Hu Y, Ribbe MW. PMID: 25205285; PMCID: PMC4240507.
View in:
PubMed Mentions:
25 Fields:
Translation:
Cells
-
A journey into the active center of nitrogenase. J Biol Inorg Chem. 2014 Aug; 19(6):731-6.
Hu Y, Ribbe MW. PMID: 24752864; PMCID: PMC4119499.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
-
Nonenzymatic synthesis of the P-cluster in the nitrogenase MoFe protein: evidence of the involvement of all-ferrous [Fe4S4](0) intermediates. Biochemistry. 2014 Feb 25; 53(7):1108-16.
Rupnik K, Lee CC, Wiig JA, Hu Y, Ribbe MW, Hales BJ. PMID: 24520862; PMCID: PMC3970913.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
-
Cleaving the n,n triple bond: the transformation of dinitrogen to ammonia by nitrogenases. Met Ions Life Sci. 2014; 14:147-76.
Lee CC, Ribbe MW, Hu Y. PMID: 25416394.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
-
Biosynthesis of nitrogenase metalloclusters. Chem Rev. 2014 Apr 23; 114(8):4063-80.
Ribbe MW, Hu Y, Hodgson KO, Hedman B. PMID: 24328215; PMCID: PMC3999185.
View in:
PubMed Mentions:
54 Fields:
-
Reduction of fluorinated cyclopropene by nitrogenase. J Am Chem Soc. 2013 Jul 17; 135(28):10346-52.
Ni F, Lee CC, Hwang CS, Hu Y, Ribbe MW, McKenna CE. PMID: 23834519.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
-
Biosynthesis of the iron-molybdenum cofactor of nitrogenase. J Biol Chem. 2013 May 10; 288(19):13173-7.
Hu Y, Ribbe MW. PMID: 23539617; PMCID: PMC3650356.
View in:
PubMed Mentions:
25 Fields:
Translation:
Cells
-
Tracing the interstitial carbide of the nitrogenase cofactor during substrate turnover. J Am Chem Soc. 2013 Apr 03; 135(13):4982-3.
Wiig JA, Lee CC, Hu Y, Ribbe MW. PMID: 23514429; PMCID: PMC3726556.
View in:
PubMed Mentions:
24 Fields:
Translation:
Cells
-
Structure of ADP-aluminium fluoride-stabilized protochlorophyllide oxidoreductase complex. Proc Natl Acad Sci U S A. 2013 Feb 05; 110(6):2094-8.
Moser J, Lange C, Krausze J, Rebelein J, Schubert WD, Ribbe MW, Heinz DW, Jahn D. PMID: 23341615; PMCID: PMC3568340.
View in:
PubMed Mentions:
27 Fields:
Translation:
Cells
-
X-ray spectroscopic observation of an interstitial carbide in NifEN-bound FeMoco precursor. J Am Chem Soc. 2013 Jan 16; 135(2):610-2.
Lancaster KM, Hu Y, Bergmann U, Ribbe MW, DeBeer S. PMID: 23276198; PMCID: PMC3555700.
View in:
PubMed Mentions:
33 Fields:
Translation:
Cells
-
Nitrogenase assembly. Biochim Biophys Acta. 2013 Aug-Sep; 1827(8-9):1112-22.
Hu Y, Ribbe MW. PMID: 23232096; PMCID: PMC3622157.
View in:
PubMed Mentions:
30 Fields:
Translation:
Cells
-
Radical SAM-dependent carbon insertion into the nitrogenase M-cluster. Science. 2012 Sep 28; 337(6102):1672-5.
Wiig JA, Hu Y, Chung Lee C, Ribbe MW. PMID: 23019652; PMCID: PMC3836454.
View in:
PubMed Mentions:
105 Fields:
Translation:
Cells
-
P+ state of nitrogenase p-cluster exhibits electronic structure of a [Fe4S4]+ cluster. J Am Chem Soc. 2012 Aug 22; 134(33):13749-54.
Rupnik K, Hu Y, Lee CC, Wiig JA, Ribbe MW, Hales BJ. PMID: 22839751; PMCID: PMC3442605.
View in:
PubMed Mentions:
19 Fields:
Translation:
Cells
-
ATP-independent substrate reduction by nitrogenase P-cluster variant. Proc Natl Acad Sci U S A. 2012 May 01; 109(18):6922-6.
Lee CC, Hu Y, Ribbe MW. PMID: 22509042; PMCID: PMC3344972.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
-
ATP-independent formation of hydrocarbons catalyzed by isolated nitrogenase cofactors. Angew Chem Int Ed Engl. 2012 Feb 20; 51(8):1947-9.
Lee CC, Hu Y, Ribbe MW. PMID: 22253035; PMCID: PMC3516927.
View in:
PubMed Mentions:
20 Fields:
Translation:
Cells
-
Biosynthesis of the metalloclusters of molybdenum nitrogenase. Microbiol Mol Biol Rev. 2011 Dec; 75(4):664-77.
Hu Y, Ribbe MW. PMID: 22126998; PMCID: PMC3232738.
View in:
PubMed Mentions:
19 Fields:
Translation:
Cells
-
Vanadium nitrogenase: a two-hit wonder? Dalton Trans. 2012 Jan 28; 41(4):1118-27.
Hu Y, Lee CC, Ribbe MW. PMID: 22101422; PMCID: PMC3823560.
View in:
PubMed Mentions:
39 Fields:
Translation:
Cells
-
X-ray emission spectroscopy evidences a central carbon in the nitrogenase iron-molybdenum cofactor. Science. 2011 Nov 18; 334(6058):974-7.
Lancaster KM, Roemelt M, Ettenhuber P, Hu Y, Ribbe MW, Neese F, Bergmann U, DeBeer S. PMID: 22096198; PMCID: PMC3800678.
View in:
PubMed Mentions:
250 Fields:
Translation:
Cells
-
Extending the carbon chain: hydrocarbon formation catalyzed by vanadium/molybdenum nitrogenases. Science. 2011 Aug 05; 333(6043):753-5.
Hu Y, Lee CC, Ribbe MW. PMID: 21817053; PMCID: PMC3153399.
View in:
PubMed Mentions:
86 Fields:
Translation:
Cells
-
Spectroscopic characterization of the isolated iron-molybdenum cofactor (FeMoco) precursor from the protein NifEN. Angew Chem Int Ed Engl. 2011 Aug 16; 50(34):7787-90.
Fay AW, Blank MA, Lee CC, Hu Y, Hodgson KO, Hedman B, Ribbe MW. PMID: 21726031; PMCID: PMC3395727.
View in:
PubMed Mentions:
29 Fields:
-
Structural models of the [Fe4S4] clusters of homologous nitrogenase Fe proteins. Inorg Chem. 2011 Aug 01; 50(15):7123-8.
Blank MA, Lee CC, Hu Y, Hodgson KO, Hedman B, Ribbe MW. PMID: 21718019; PMCID: PMC3143205.
View in:
PubMed Mentions:
15 Fields:
Translation:
Cells
-
NifEN-B complex of Azotobacter vinelandii is fully functional in nitrogenase FeMo cofactor assembly. Proc Natl Acad Sci U S A. 2011 May 24; 108(21):8623-7.
Wiig JA, Hu Y, Ribbe MW. PMID: 21551100; PMCID: PMC3102359.
View in:
PubMed Mentions:
35 Fields:
Translation:
Cells
-
Biosynthesis of Nitrogenase FeMoco. Coord Chem Rev. 2011 May 01; 255(9-10):1218-1224.
Hu Y, Ribbe MW. PMID: 21503270; PMCID: PMC3077758.
View in:
PubMed Mentions:
26
-
Tracing the hydrogen source of hydrocarbons formed by vanadium nitrogenase. Angew Chem Int Ed Engl. 2011 Jun 06; 50(24):5545-7.
Lee CC, Hu Y, Ribbe MW. PMID: 21538750.
View in:
PubMed Mentions:
23 Fields:
Translation:
Cells
-
[4Fe4S]2+ clusters exhibit ground-state paramagnetism. J Am Chem Soc. 2011 May 11; 133(18):6871-3.
Rupnik K, Lee CC, Hu Y, Ribbe MW, Hales BJ. PMID: 21488637; PMCID: PMC3088508.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
-
Structure of precursor-bound NifEN: a nitrogenase FeMo cofactor maturase/insertase. Science. 2011 Jan 07; 331(6013):91-4.
Kaiser JT, Hu Y, Wiig JA, Rees DC, Ribbe MW. PMID: 21212358; PMCID: PMC3138709.
View in:
PubMed Mentions:
60 Fields:
Translation:
Cells
-
Historic overview of nitrogenase research. Methods Mol Biol. 2011; 766:3-7.
Hu Y, Ribbe MW. PMID: 21833857.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Assembly of nitrogenase MoFe protein. Methods Mol Biol. 2011; 766:31-47.
Lee CC, Fay AW, Wiig JA, Ribbe MW, Hu Y. PMID: 21833859.
View in:
PubMed Mentions: Fields:
Translation:
Cells
-
Purification of nitrogenase proteins. Methods Mol Biol. 2011; 766:93-103.
Wiig JA, Lee CC, Fay AW, Hu Y, Ribbe MW. PMID: 21833863.
View in:
PubMed Mentions:
2 Fields:
-
Protocols for cofactor isolation of nitrogenase. Methods Mol Biol. 2011; 766:239-48.
Fay AW, Lee CC, Wiig JA, Hu Y, Ribbe MW. PMID: 21833872.
View in:
PubMed Mentions:
7 Fields:
-
Variable-temperature, variable-field magnetic circular dichroism spectroscopic study of NifEN-bound precursor and "FeMoco". J Biol Inorg Chem. 2011 Feb; 16(2):325-32.
Rupnik K, Hu Y, Fay AW, Ribbe MW, Hales BJ. PMID: 21038112; PMCID: PMC3032186.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Characterization of isolated nitrogenase FeVco. J Am Chem Soc. 2010 Sep 15; 132(36):12612-8.
Fay AW, Blank MA, Lee CC, Hu Y, Hodgson KO, Hedman B, Ribbe MW. PMID: 20718463; PMCID: PMC2940275.
View in:
PubMed Mentions:
34 Fields:
Translation:
Cells
-
Vanadium nitrogenase reduces CO. Science. 2010 Aug 06; 329(5992):642.
Lee CC, Hu Y, Ribbe MW. PMID: 20689010; PMCID: PMC3141295.
View in:
PubMed Mentions:
104 Fields:
Translation:
Cells
-
Decoding the nitrogenase mechanism: the homologue approach. Acc Chem Res. 2010 Mar 16; 43(3):475-84.
Hu Y, Ribbe MW. PMID: 20030377; PMCID: PMC2840065.
View in:
PubMed Mentions:
15 Fields:
Translation:
Cells
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Formation of a homocitrate-free iron-molybdenum cluster on NifEN: implications for the role of homocitrate in nitrogenase assembly. Dalton Trans. 2010 Mar 28; 39(12):3124-30.
Fay AW, Blank MA, Yoshizawa JM, Lee CC, Wiig JA, Hu Y, Hodgson KO, Hedman B, Ribbe MW. PMID: 20221547; PMCID: PMC3027845.
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PubMed Mentions:
11 Fields:
Translation:
Cells
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Dual functions of NifEN: insights into the evolution and mechanism of nitrogenase. Dalton Trans. 2010 Mar 28; 39(12):2964-71.
Hu Y, Fay AW, Lee CC, Wiig JA, Ribbe MW. PMID: 20221527; PMCID: PMC3030252.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Insertion of heterometals into the NifEN-associated iron-molybdenum cofactor precursor. J Biol Inorg Chem. 2010 Mar; 15(3):421-8.
Yoshizawa JM, Fay AW, Lee CC, Hu Y, Ribbe MW. PMID: 19967421; PMCID: PMC2830607.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Stepwise formation of P-cluster in nitrogenase MoFe protein. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18474-8.
Lee CC, Blank MA, Fay AW, Yoshizawa JM, Hu Y, Hodgson KO, Hedman B, Ribbe MW. PMID: 19828444; PMCID: PMC2774011.
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PubMed Mentions:
27 Fields:
Translation:
Cells
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Catalytic activities of NifEN: implications for nitrogenase evolution and mechanism. Proc Natl Acad Sci U S A. 2009 Oct 06; 106(40):16962-6.
Hu Y, Yoshizawa JM, Fay AW, Lee CC, Wiig JA, Ribbe MW. PMID: 19805110; PMCID: PMC2761346.
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PubMed Mentions:
19 Fields:
Translation:
Cells
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Molybdenum cofactors, enzymes and pathways. Nature. 2009 Aug 13; 460(7257):839-47.
Schwarz G, Mendel RR, Ribbe MW. PMID: 19675644.
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PubMed Mentions:
254 Fields:
Translation:
HumansAnimals
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Optimization of FeMoco maturation on NifEN. J Am Chem Soc. 2009 Jul 08; 131(26):9321-5.
Yoshizawa JM, Blank MA, Fay AW, Lee CC, Wiig JA, Hu Y, Hodgson KO, Hedman B, Ribbe MW. PMID: 19514721; PMCID: PMC2716083.
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PubMed Mentions:
33 Fields:
Translation:
Cells
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Unique features of the nitrogenase VFe protein from Azotobacter vinelandii. Proc Natl Acad Sci U S A. 2009 Jun 09; 106(23):9209-14.
Lee CC, Hu Y, Ribbe MW. PMID: 19478062; PMCID: PMC2695066.
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PubMed Mentions:
44 Fields:
Translation:
Cells
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VTVH-MCD study of the Delta nifB Delta nifZ MoFe protein from Azotobacter vinelandii. J Am Chem Soc. 2009 Apr 08; 131(13):4558-9.
Cotton MS, Rupnik K, Broach RB, Hu Y, Fay AW, Ribbe MW, Hales BJ. PMID: 19334767.
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PubMed Mentions:
14 Fields:
Translation:
Cells
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Chimeric nitrogenase-like enzymes of (bacterio)chlorophyll biosynthesis. J Biol Chem. 2009 Jun 05; 284(23):15530-40.
Wätzlich D, Bröcker MJ, Uliczka F, Ribbe M, Virus S, Jahn D, Moser J. PMID: 19336405; PMCID: PMC2708849.
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PubMed Mentions:
13 Fields:
Translation:
Cells
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Assembly of nitrogenase MoFe protein. Biochemistry. 2008 Apr 01; 47(13):3973-81.
Hu Y, Fay AW, Lee CC, Yoshizawa J, Ribbe MW. PMID: 18314963.
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PubMed Mentions:
47 Fields:
Translation:
Cells
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Conformational differences between Azotobacter vinelandii nitrogenase MoFe proteins as studied by small-angle X-ray scattering. Biochemistry. 2007 Jul 10; 46(27):8066-74.
Corbett MC, Hu Y, Fay AW, Tsuruta H, Ribbe MW, Hodgson KO, Hedman B. PMID: 17567155.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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P-cluster maturation on nitrogenase MoFe protein. Proc Natl Acad Sci U S A. 2007 Jun 19; 104(25):10424-9.
Hu Y, Fay AW, Lee CC, Ribbe MW. PMID: 17563349; PMCID: PMC1965529.
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PubMed Mentions:
38 Fields:
Translation:
Cells
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Molecular insights into nitrogenase FeMoco insertion--the role of His 274 and His 451 of MoFe protein alpha subunit. J Inorg Biochem. 2007 Nov; 101(11-12):1630-41.
Fay AW, Hu Y, Schmid B, Ribbe MW. PMID: 17521738; PMCID: PMC2935933.
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PubMed Mentions:
14 Fields:
Translation:
Cells
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Molecular insights into nitrogenase FeMo cofactor insertion: the role of His 362 of the MoFe protein alpha subunit in FeMo cofactor incorporation. J Biol Inorg Chem. 2007 May; 12(4):449-60.
Hu Y, Fay AW, Ribbe MW. PMID: 17203313.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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Variable-temperature, variable-field magnetic circular dichroism spectroscopic study of the metal clusters in the DeltanifB and DeltanifH mofe proteins of nitrogenase from Azotobacter vinelandii. Biochemistry. 2006 Dec 19; 45(50):15039-48.
Broach RB, Rupnik K, Hu Y, Fay AW, Cotton M, Ribbe MW, Hales BJ. PMID: 17154541.
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PubMed Mentions:
17 Fields:
Translation:
Cells
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Nitrogenase Fe protein: A molybdate/homocitrate insertase. Proc Natl Acad Sci U S A. 2006 Nov 14; 103(46):17125-30.
Hu Y, Corbett MC, Fay AW, Webber JA, Hodgson KO, Hedman B, Ribbe MW. PMID: 17062756; PMCID: PMC1859896.
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PubMed Mentions:
46 Fields:
Translation:
Cells
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FeMo cofactor maturation on NifEN. Proc Natl Acad Sci U S A. 2006 Nov 14; 103(46):17119-24.
Hu Y, Corbett MC, Fay AW, Webber JA, Hodgson KO, Hedman B, Ribbe MW. PMID: 17050696; PMCID: PMC1859895.
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PubMed Mentions:
53 Fields:
Translation:
Cells
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Molecular insights into nitrogenase FeMoco insertion: TRP-444 of MoFe protein alpha-subunit locks FeMoco in its binding site. J Biol Chem. 2006 Oct 13; 281(41):30534-41.
Hu Y, Fay AW, Schmid B, Makar B, Ribbe MW. PMID: 16893897.
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PubMed Mentions:
14 Fields:
Translation:
Cells
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Structural insights into a protein-bound iron-molybdenum cofactor precursor. Proc Natl Acad Sci U S A. 2006 Jan 31; 103(5):1238-43.
Corbett MC, Hu Y, Fay AW, Ribbe MW, Hedman B, Hodgson KO. PMID: 16423898; PMCID: PMC1360540.
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PubMed Mentions:
55 Fields:
Translation:
Cells
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Nitrogenase reactivity with P-cluster variants. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):13825-30.
Hu Y, Corbett MC, Fay AW, Webber JA, Hedman B, Hodgson KO, Ribbe MW. PMID: 16166259; PMCID: PMC1236593.
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PubMed Mentions:
23 Fields:
Translation:
Cells
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Identification of a nitrogenase FeMo cofactor precursor on NifEN complex. Proc Natl Acad Sci U S A. 2005 Mar 01; 102(9):3236-41.
Hu Y, Fay AW, Ribbe MW. PMID: 15728375; PMCID: PMC552928.
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PubMed Mentions:
57 Fields:
Translation:
Cells
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Competitive 15N kinetic isotope effects of nitrogenase-catalyzed dinitrogen reduction. J Am Chem Soc. 2004 Oct 13; 126(40):12768-9.
Sra AK, Hu Y, Martin GE, Snow DD, Ribbe MW, Kohen A. PMID: 15469259.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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Characterization of Azotobacter vinelandii nifZ deletion strains. Indication of stepwise MoFe protein assembly. J Biol Chem. 2004 Dec 24; 279(52):54963-71.
Hu Y, Fay AW, Dos Santos PC, Naderi F, Ribbe MW. PMID: 15485884.
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PubMed Mentions:
30 Fields:
Translation:
Cells
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Comparison of iron-molybdenum cofactor-deficient nitrogenase MoFe proteins by X-ray absorption spectroscopy: implications for P-cluster biosynthesis. J Biol Chem. 2004 Jul 02; 279(27):28276-82.
Corbett MC, Hu Y, Naderi F, Ribbe MW, Hedman B, Hodgson KO. PMID: 15102840.
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PubMed Mentions:
35 Fields:
Translation:
Cells
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Formation and insertion of the nitrogenase iron-molybdenum cofactor. Chem Rev. 2004 Feb; 104(2):1159-73.
Dos Santos PC, Dean DR, Hu Y, Ribbe MW. PMID: 14871152.
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PubMed Mentions:
62 Fields:
Translation:
Cells
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Direct assessment of the reduction potential of the [4Fe-4S](1+/0) couple of the Fe protein from Azotobacter vinelandii. J Am Chem Soc. 2002 Oct 16; 124(41):12100-1.
Guo M, Sulc F, Ribbe MW, Farmer PJ, Burgess BK. PMID: 12371842.
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PubMed Mentions:
23 Fields:
Translation:
Cells
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The FeMoco-deficient MoFe protein produced by a nifH deletion strain of Azotobacter vinelandii shows unusual P-cluster features. J Biol Chem. 2002 Jun 28; 277(26):23469-76.
Ribbe MW, Hu Y, Guo M, Schmid B, Burgess BK. PMID: 11978793.
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PubMed Mentions:
39 Fields:
Translation:
Cells
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Structure of a cofactor-deficient nitrogenase MoFe protein. Science. 2002 Apr 12; 296(5566):352-6.
Schmid B, Ribbe MW, Einsle O, Yoshida M, Thomas LM, Dean DR, Rees DC, Burgess BK. PMID: 11951047.
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PubMed Mentions:
68 Fields:
Translation:
Cells
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The chaperone GroEL is required for the final assembly of the molybdenum-iron protein of nitrogenase. Proc Natl Acad Sci U S A. 2001 May 08; 98(10):5521-5.
Ribbe MW, Burgess BK. PMID: 11331775; PMCID: PMC33245.
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PubMed Mentions:
20 Fields:
Translation:
Cells
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Identification of an Fe protein residue (Glu146) of Azotobacter vinelandii nitrogenase that is specifically involved in FeMo cofactor insertion. J Biol Chem. 2000 Jun 09; 275(23):17631-8.
Ribbe MW, Bursey EH, Burgess BK. PMID: 10837496.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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N2 fixation by Streptomyces thermoautotrophicus involves a molybdenum-dinitrogenase and a manganese-superoxide oxidoreductase that couple N2 reduction to the oxidation of superoxide produced from O2 by a molybdenum-CO dehydrogenase. J Biol Chem. 1997 Oct 17; 272(42):26627-33.
Ribbe M, Gadkari D, Meyer O. PMID: 9334244.
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PubMed Mentions:
26 Fields:
Translation:
Cells