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Haik Mkhikian

Title(s)Clinical Instructor, Pathology
Phone(714) 456-6141
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    N-glycosylation as a downstream effector of Interleukin-7
    NIH/NHLBI F30HL108451Apr 22, 2011 - Apr 21, 2016
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Mkhikian H, Crews BO. A Striking Contrast. Clin Chem. 2018 08; 64(8):1265-1266. PMID: 30054304.
      View in: PubMed
    2. Tran MH, Mkhikian H, Sy M, Perez-Alvarez I, Demetriou M. Long-term plasma exchange as maintenance therapy for cerebellar-type Hashimoto's encephalopathy, a case report. Transfus Apher Sci. 2018 Jun; 57(3):418-420. PMID: 29891220.
      View in: PubMed
    3. Araujo L, Khim P, Mkhikian H, Mortales CL, Demetriou M. Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation. Elife. 2017 01 06; 6. PMID: 28059703.
      View in: PubMed
    4. Mkhikian H, Tran MH. Exacerbation of myasthenia symptoms following intravenous iron administration. Transfus Med. 2016 Oct; 26(5):381-382. PMID: 27527607.
      View in: PubMed
    5. Mkhikian H, Mortales CL, Zhou RW, Khachikyan K, Wu G, Haslam SM, Kavarian P, Dell A, Demetriou M. Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis. Elife. 2016 06 08; 5. PMID: 27269286.
      View in: PubMed
    6. Zhou RW, Mkhikian H, Grigorian A, Hong A, Chen D, Arakelyan A, Demetriou M. N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca²? signaling. Nat Immunol. 2014 Nov; 15(11):1038-45. PMID: 25263124.
      View in: PubMed
    7. Yu Z, Li CF, Mkhikian H, Zhou RW, Newton BL, Demetriou M. Family studies of type 1 diabetes reveal additive and epistatic effects between MGAT1 and three other polymorphisms. Genes Immun. 2014 Apr; 15(4):218-23. PMID: 24572742.
      View in: PubMed
    8. Li CF, Zhou RW, Mkhikian H, Newton BL, Yu Z, Demetriou M. Hypomorphic MGAT5 polymorphisms promote multiple sclerosis cooperatively with MGAT1 and interleukin-2 and 7 receptor variants. J Neuroimmunol. 2013 Mar 15; 256(1-2):71-6. PMID: 23351704.
      View in: PubMed
    9. Grigorian A, Mkhikian H, Li CF, Newton BL, Zhou RW, Demetriou M. Pathogenesis of multiple sclerosis via environmental and genetic dysregulation of N-glycosylation. Semin Immunopathol. 2012 May; 34(3):415-24. PMID: 22488447.
      View in: PubMed
    10. Grigorian A, Mkhikian H, Demetriou M. Interleukin-2, Interleukin-7, T cell-mediated autoimmunity, and N-glycosylation. Ann N Y Acad Sci. 2012 Apr; 1253:49-57. PMID: 22288682.
      View in: PubMed
    11. Mkhikian H, Grigorian A, Li CF, Chen HL, Newton B, Zhou RW, Beeton C, Torossian S, Tatarian GG, Lee SU, Lau K, Walker E, Siminovitch KA, Chandy KG, Yu Z, Dennis JW, Demetriou M. Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis. Nat Commun. 2011; 2:334. PMID: 21629267.
      View in: PubMed
    12. Androutsellis-Theotokis A, Rueger MA, Park DM, Mkhikian H, Korb E, Poser SW, Walbridge S, Munasinghe J, Koretsky AP, Lonser RR, McKay RD. Targeting neural precursors in the adult brain rescues injured dopamine neurons. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13570-5. PMID: 19628689.
      View in: PubMed
    13. Androutsellis-Theotokis A, Rueger MA, Mkhikian H, Korb E, McKay RD. Signaling pathways controlling neural stem cells slow progressive brain disease. Cold Spring Harb Symp Quant Biol. 2008; 73:403-10. PMID: 19022746.
      View in: PubMed