Gordon D Mclaren

Title(s)Emeritus, Medicine
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-5153
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    Genetic Modifiers of Iron Status in Hemochromatosis HFE C282Y Homozygotes
    NIH R24DK099846Sep 1, 2014 - Jun 30, 2019
    Role: Principal Investigator
    Genetic Modifiers of Iron Status in Hemochromatosis HFE C282Y Homozygotes
    NIH R24DK093433Sep 15, 2011 - Aug 31, 2014
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Abdominal pain and cirrhosis at diagnosis of hemochromatosis: Analysis of 219 referred probands with HFE p.C282Y homozygosity and a literature review. PLoS One. 2021; 16(12):e0261690. Barton JC, Barton JC, Patel N, McLaren GD. PMID: 34932603; PMCID: PMC8691644.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels. Blood Cells Mol Dis. 2020 11; 85:102463. Secondes ES, Wallace DF, Rishi G, McLaren GD, McLaren CE, Chen WP, Ramm LE, Powell LW, Ramm GA, Barton JC, Subramaniam VN. PMID: 32652459; PMCID: PMC7786288.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Prevalence of iron deficiency in 62,685 women of seven race/ethnicity groups: The HEIRS Study. PLoS One. 2020; 15(4):e0232125. Barton JC, Wiener HH, Acton RT, Adams PC, Eckfeldt JH, Gordeuk VR, Harris EL, McLaren CE, Harrison H, McLaren GD, Reboussin DM. PMID: 32324809; PMCID: PMC7179917.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    4. Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes. Ann Hepatol. 2018 Aug 24; 17(5):871-879. Barton JC, McLaren CE, Chen WP, Ramm GA, Anderson GJ, Powell LW, Subramaniam VN, Adams PC, Phatak PD, Gurrin LC, Phillips JD, Parker CJ, Emond MJ, McLaren GD. PMID: 30145563; PMCID: PMC6368858.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    5. Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype. Hepatol Int. 2018 Mar; 12(2):83-86. Adams P, Altes A, Brissot P, Butzeck B, Cabantchik I, Cançado R, Distante S, Evans P, Evans R, Ganz T, Girelli D, Hultcrantz R, McLaren G, Marris B, Milman N, Nemeth E, Nielsen P, Pineau B, Piperno A, Porto G, Prince D, Ryan J, Sanchez M, Santos P, Swinkels D, Teixeira E, Toska K, Vanclooster A, White D, Contributors and Hemochromatosis International Taskforce. PMID: 29589198; PMCID: PMC5904234.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    6. Reply. Hepatology. 2017 03; 65(3):1072-1073. McLaren GD, Barton JC, Ramm GA, Emond MJ, Subramaniam VN, Phatak PD, Adams PC, Powell LW, Gurrin LC, Anderson GJ, McLaren CE. PMID: 28010035; PMCID: PMC5319902.
      View in: PubMed   Mentions: 1     Fields:    
    7. GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes. Blood Cells Mol Dis. 2017 03; 63:15-20. Barton JC, Chen WP, Emond MJ, Phatak PD, Subramaniam VN, Adams PC, Gurrin LC, Anderson GJ, Ramm GA, Powell LW, Allen KJ, Phillips JD, Parker CJ, McLaren GD, McLaren CE. PMID: 27936396; PMCID: PMC5629344.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    8. The D519G Polymorphism of Glyceronephosphate O-Acyltransferase Is a Risk Factor for Familial Porphyria Cutanea Tarda. PLoS One. 2016; 11(9):e0163322. Farrell CP, Overbey JR, Naik H, Nance D, McLaren GD, McLaren CE, Zhou L, Desnick RJ, Parker CJ, Phillips JD. PMID: 27661980; PMCID: PMC5035022.
      View in: PubMed   Mentions: 3     Fields:    
    9. Reply. Hepatology. 2016 06; 63(6):2058-60. McLaren CE, Barton JC, Subramaniam VN, Ramm GA, Phatak PD, Emond MJ, Gurrin LC, Adams PC, Powell LW, Anderson GJ, McLaren GD. PMID: 26845080; PMCID: PMC4874893.
      View in: PubMed   Mentions:    Fields:    
    10. Reply. Hepatology. 2016 06; 63(6):2056-7. McLaren CE, Barton JC, Phatak PD, Emond MJ, Subramaniam VN, Gurrin LC, Adams PC, Powell LW, Ramm GA, Anderson GJ, McLaren GD. PMID: 26417986; PMCID: PMC4811743.
      View in: PubMed   Mentions:    Fields:    
    11. Reply: To PMID 25605615. Hepatology. 2015 Dec; 62(6):1918-9. McLaren CE, Emond MJ, Subramaniam VN, Phatak PD, Barton JC, Adams PC, Powell LW, Gurrin LC, Ramm GA, Anderson GJ, McLaren GD. PMID: 25914125.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload. Hepatology. 2015 Aug; 62(2):429-39. McLaren CE, Emond MJ, Subramaniam VN, Phatak PD, Barton JC, Adams PC, Goh JB, McDonald CJ, Powell LW, Gurrin LC, Allen KJ, Nickerson DA, Louie T, Ramm GA, Anderson GJ, McLaren GD. PMID: 25605615; PMCID: PMC4508230.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    13. Elevated transferrin saturation, health-related quality of life and telomere length. Biometals. 2014 Feb; 27(1):135-41. Mainous AG, Wright RU, Hulihan MM, Twal WO, McLaren CE, Diaz VA, McLaren GD, Argraves WS, Grant AM. PMID: 24337410; PMCID: PMC4034347.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    14. HFE mutations in Caucasian participants of the Hemochromatosis and Iron Overload Screening study with serum ferritin level <1000 µg/L. Can J Gastroenterol. 2013 Jul; 27(7):390-2. Adams PC, McLaren CE, Speechley M, McLaren GD, Barton JC, Eckfeldt JH. PMID: 23862168; PMCID: PMC3956024.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    15. Telomere length and elevated iron: the influence of phenotype and HFE genotype. Am J Hematol. 2013 Jun; 88(6):492-6. Mainous AG, Wright RU, Hulihan MM, Twal WO, McLaren CE, Diaz VA, McLaren GD, Argraves WS, Grant AM. PMID: 23512844; PMCID: PMC3784668.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    16. Randomized trial of physician alerts for thromboprophylaxis after discharge. Am J Med. 2013 May; 126(5):435-42. Piazza G, Anderson FA, Ortel TL, Cox MJ, Rosenberg DJ, Rahimian S, Pendergast WJ, McLaren GD, Welker JA, Akus JJ, Stevens SM, Elliott CG, Freeman AL, Patton WF, Dabbagh O, Wyman A, Huang W, Rao AF, Goldhaber SZ. PMID: 23510945.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    17. Association between celiac disease and iron deficiency in Caucasians, but not non-Caucasians. Clin Gastroenterol Hepatol. 2013 Jul; 11(7):808-14. Murray JA, McLachlan S, Adams PC, Eckfeldt JH, Garner CP, Vulpe CD, Gordeuk VR, Brantner T, Leiendecker-Foster C, Killeen AA, Acton RT, Barcellos LF, Nickerson DA, Beckman KB, McLaren GD, McLaren CE. PMID: 23416278; PMCID: PMC3843318.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    18. Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations. PLoS One. 2012; 7(6):e38339. McLaren CE, McLachlan S, Garner CP, Vulpe CD, Gordeuk VR, Eckfeldt JH, Adams PC, Acton RT, Murray JA, Leiendecker-Foster C, Snively BM, Barcellos LF, Cook JD, McLaren GD. PMID: 22761678; PMCID: PMC3382217.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    19. New mechanistic explanation for the localization of ulcers in the rat duodenum: role of iron and selective uptake of cysteamine. Arch Biochem Biophys. 2012 Sep 01; 525(1):60-70. Khomenko T, Kolodney J, Pinto JT, McLaren GD, Deng X, Chen L, Tolstanova G, Paunovic B, Krasnikov BF, Hoa N, Cooper AJ, Szabo S. PMID: 22684023.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    20. Dietary iron intake and serum ferritin concentration in 213 patients homozygous for the HFEC282Y hemochromatosis mutation. Can J Gastroenterol. 2012 Jun; 26(6):345-9. Gordeuk VR, Lovato L, Barton J, Vitolins M, McLaren G, Acton R, McLaren C, Harris E, Speechley M, Eckfeldt JH, Diaz S, Sholinsky P, Adams P. PMID: 22720276; PMCID: PMC3378281.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
    21. Probability of C282Y homozygosity decreases as liver transaminase activities increase in participants with hyperferritinemia in the hemochromatosis and iron overload screening study. Hepatology. 2012 Jun; 55(6):1722-6. Adams PC, Speechley M, Barton JC, McLaren CE, McLaren GD, Eckfeldt JH. PMID: 22183642; PMCID: PMC3355194.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression. Br J Haematol. 2012 Jun; 157(5):615-26. Frazer DM, Wilkins SJ, Darshan D, Badrick AC, McLaren GD, Anderson GJ. PMID: 22449175.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    23. IRon Overload screeNing tool (IRON): development of a tool to guide screening in primary care. Am J Hematol. 2011 Sep; 86(9):733-7. Mainous AG, Diaz VA, Everett CJ, Knoll ME, Hulihan MM, Grant AM, McLaren CE, McLaren GD. PMID: 21800355; PMCID: PMC3779368.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    24. Genome-wide association study identifies genetic loci associated with iron deficiency. PLoS One. 2011 Mar 31; 6(3):e17390. McLaren CE, Garner CP, Constantine CC, McLachlan S, Vulpe CD, Snively BM, Gordeuk VR, Nickerson DA, Cook JD, Leiendecker-Foster C, Beckman KB, Eckfeldt JH, Barcellos LF, Murray JA, Adams PC, Acton RT, Killeen AA, McLaren GD. PMID: 21483845; PMCID: PMC3069025.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    25. A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis. Hepatology. 2010 Nov; 52(5):1671-779. Phatak P, Brissot P, Wurster M, Adams PC, Bonkovsky HL, Gross J, Malfertheiner P, McLaren GD, Niederau C, Piperno A, Powell LW, Russo MW, Stoelzel U, Stremmel W, Griffel L, Lynch N, Zhang Y, Pietrangelo A. PMID: 20814896; PMCID: PMC3034044.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    26. Heritability of serum iron measures in the hemochromatosis and iron overload screening (HEIRS) family study. Am J Hematol. 2010 Feb; 85(2):101-5. McLaren CE, Barton JC, Eckfeldt JH, McLaren GD, Acton RT, Adams PC, Henkin LF, Gordeuk VR, Vulpe CD, Harris EL, Harrison BW, Reiss JA, Snively BM. PMID: 20095037; PMCID: PMC3816512.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    27. Screening for iron overload: lessons from the hemochromatosis and iron overload screening (HEIRS) study. Can J Gastroenterol. 2009 Nov; 23(11):769-72. Adams P, Barton JC, McLaren GD, Acton RT, Speechley M, McLaren CE, Reboussin DM, Leiendecker-Foster C, Harris EL, Snively BM, Vogt T, Sholinsky P, Thomson E, Dawkins FW, Gordeuk VR, Eckfeldt JH. PMID: 19893773; PMCID: PMC2777090.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    28. Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Oct 15; 877(28):3434-41. Pinto JT, Khomenko T, Szabo S, McLaren GD, Denton TT, Krasnikov BF, Jeitner TM, Cooper AJ. PMID: 19523884; PMCID: PMC2752955.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    29. Physician alerts to prevent symptomatic venous thromboembolism in hospitalized patients. Circulation. 2009 Apr 28; 119(16):2196-201. Piazza G, Rosenbaum EJ, Pendergast W, Jacobson JO, Pendleton RC, McLaren GD, Elliott CG, Stevens SM, Patton WF, Dabbagh O, Paterno MD, Catapane E, Li Z, Goldhaber SZ. PMID: 19364975; PMCID: PMC2901546.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    30. Role of iron in the pathogenesis of cysteamine-induced duodenal ulceration in rats. Am J Physiol Gastrointest Liver Physiol. 2009 Jun; 296(6):G1277-86. Khomenko T, Szabo S, Deng X, Ishikawa H, Anderson GJ, McLaren GD. PMID: 19342511; PMCID: PMC3834006.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    31. Iron absorption and metabolism. Curr Opin Gastroenterol. 2009 Mar; 25(2):129-35. Anderson GJ, Frazer DM, McLaren GD. PMID: 19528880.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    32. Heme carrier protein 1 (HCP1) genetic variants in the Hemochromatosis and Iron Overload Screening (HEIRS) Study participants. Blood Cells Mol Dis. 2009 Mar-Apr; 42(2):150-4. Wang X, Leiendecker-Foster C, Acton RT, Barton JC, McLaren CE, McLaren GD, Gordeuk VR, Eckfeldt JH. PMID: 19176287; PMCID: PMC2710880.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    33. HFE C282Y homozygosity is associated with lower total and low-density lipoprotein cholesterol: The hemochromatosis and iron overload screening study. Circ Cardiovasc Genet. 2009 Feb; 2(1):34-7. Adams PC, Pankow JS, Barton JC, Acton RT, Leiendecker-Foster C, McLaren GD, Speechley M, Eckfeldt JH. PMID: 20031565.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansPHPublic Health
    34. Hereditary hemochromatosis: insights from the Hemochromatosis and Iron Overload Screening (HEIRS) Study. Hematology Am Soc Hematol Educ Program. 2009; 195-206. McLaren GD, Gordeuk VR. PMID: 20008199; PMCID: PMC3829617.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansPHPublic Health
    35. Clinical manifestations of hemochromatosis in HFE C282Y homozygotes identified by screening. Can J Gastroenterol. 2008 Nov; 22(11):923-30. McLaren GD, McLaren CE, Adams PC, Barton JC, Reboussin DM, Gordeuk VR, Acton RT, Harris EL, Speechley MR, Sholinsky P, Dawkins FW, Snively BM, Vogt TM, Eckfeldt JH, Hemochromatosis and Iron Overload Screen (HEIRS) Study Research Investigators. PMID: 19018338; PMCID: PMC2661195.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    36. Serum ferritin concentrations and body iron stores in a multicenter, multiethnic primary-care population. Am J Hematol. 2008 Aug; 83(8):618-26. Gordeuk VR, Reboussin DM, McLaren CE, Barton JC, Acton RT, McLaren GD, Harris EL, Reiss JA, Adams PC, Speechley M, Phatak PD, Sholinsky P, Eckfeldt JH, Chen WP, Passmore L, Dawkins FW. PMID: 18429050; PMCID: PMC3773165.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    37. Serial serum ferritin measurements in untreated HFE C282Y homozygotes in the Hemochromatosis and Iron Overload Screening Study. Int J Lab Hematol. 2008 Aug; 30(4):300-5. Adams PC, Reboussin DM, Barton JC, Acton RT, Speechley M, Leiendecker-Foster C, Meenan R, Passmore L, McLaren CE, McLaren GD, Gordeuk V, Dawkins F, Eckfeldt JH. PMID: 18665827.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    38. Accuracy of family history of hemochromatosis or iron overload: the hemochromatosis and iron overload screening study. Clin Gastroenterol Hepatol. 2008 Aug; 6(8):934-8. Acton RT, Barton JC, Passmore LV, Adams PC, McLaren GD, Leiendecker-Foster C, Speechley MR, Harris EL, Castro O, Reiss JA, Snively BM, Harrison BW, McLaren CE. PMID: 18585964; PMCID: PMC3779058.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Characteristics of participants with self-reported hemochromatosis or iron overload at HEIRS study initial screening. Am J Hematol. 2008 Feb; 83(2):126-32. Barton JC, Acton RT, Leiendecker-Foster C, Lovato L, Adams PC, Eckfeldt JH, McLaren CE, Reiss JA, McLaren GD, Reboussin DM, Gordeuk VR, Speechley MR, Press RD, Dawkins FW, Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators. PMID: 17726683; PMCID: PMC3773364.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    40. Biological variability of transferrin saturation and unsaturated iron-binding capacity. Am J Med. 2007 Nov; 120(11):999.e1-7. Adams PC, Reboussin DM, Press RD, Barton JC, Acton RT, Moses GC, Leiendecker-Foster C, McLaren GD, Dawkins FW, Gordeuk VR, Lovato L, Eckfeldt JH. PMID: 17976429; PMCID: PMC2151312.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    41. A genome-wide linkage scan for iron phenotype quantitative trait loci: the HEIRS Family Study. Clin Genet. 2007 Jun; 71(6):518-29. Acton RT, Snively BM, Barton JC, McLaren CE, Adams PC, Rich SS, Eckfeldt JH, Press RD, Sholinsky P, Leiendecker-Foster C, McLaren GD, Speechley MR, Harris EL, Dawkins FW, Gordeuk VR, Hemochromatosis and Iron Overload Screening Study Research Investigators. PMID: 17539901.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. Serum ferritin and transferrin saturation in Asians and Pacific Islanders. Arch Intern Med. 2007 Apr 09; 167(7):722-6. Harris EL, McLaren CE, Reboussin DM, Gordeuk VR, Barton JC, Acton RT, McLaren GD, Vogt TM, Snively BM, Leiendecker-Foster C, Holup JL, Passmore LV, Eckfeldt JH, Lin E, Adams PC. PMID: 17420432.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    43. African Americans at risk for increased iron stores or liver disease. Am J Med. 2007 Aug; 120(8):734.e1-9. Dawkins FW, Gordeuk VR, Snively BM, Lovato L, Barton JC, Acton RT, McLaren GD, Leiendecker-Foster C, McLaren CE, Adams PC, Speechley M, Harris EL, Jackson S, Thomson EJ. PMID: 17679134.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    44. Association of ferroportin Q248H polymorphism with elevated levels of serum ferritin in African Americans in the Hemochromatosis and Iron Overload Screening (HEIRS) Study. Blood Cells Mol Dis. 2007 May-Jun; 38(3):247-52. Rivers CA, Barton JC, Gordeuk VR, Acton RT, Speechley MR, Snively BM, Leiendecker-Foster C, Press RD, Adams PC, McLaren GD, Dawkins FW, McLaren CE, Reboussin DM. PMID: 17276706; PMCID: PMC3727273.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsPHPublic Health
    45. Hemochromatosis (HFE) gene splice site mutation IVS5+1 G/A in North American Vietnamese with and without phenotypic evidence of iron overload. Transl Res. 2007 Feb; 149(2):92-5. Steiner M, Leiendecker-Foster C, McLaren GD, Snively BM, McLaren CE, Adams PC, Eckfeldt JH. PMID: 17240320.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    46. HFE C282Y homozygotes aged 25-29 years at HEIRS Study initial screening. Genet Test. 2007; 11(3):269-75. Barton JC, Acton RT, Leiendecker-Foster C, Lovato L, Adams PC, McLaren GD, Eckfeldt JH, McLaren CE, Reboussin DM, Gordeuk VR, Speechley MR, Reiss JA, Press RD, Dawkins FW, Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators. PMID: 17949288.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    47. Mixture models of serum iron measures in population screening for hemochromatosis and iron overload. Transl Res. 2006 Oct; 148(4):196-206. McLaren CE, Li KT, McLaren GD, Gordeuk VR, Snively BM, Reboussin DM, Barton JC, Acton RT, Dawkins FW, Harris EL, Eckfeldt JH, Moses GC, Adams PC. PMID: 17002922.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    48. Relationships of serum ferritin, transferrin saturation, and HFE mutations and self-reported diabetes in the Hemochromatosis and Iron Overload Screening (HEIRS) study. Diabetes Care. 2006 Sep; 29(9):2084-9. Acton RT, Barton JC, Passmore LV, Adams PC, Speechley MR, Dawkins FW, Sholinsky P, Reboussin DM, McLaren GD, Harris EL, Bent TC, Vogt TM, Castro O. PMID: 16936157.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansPHPublic Health
    49. Liver diseases in the hemochromatosis and iron overload screening study. Clin Gastroenterol Hepatol. 2006 Jul; 4(7):918-23; quiz 807. Adams PC, Passmore L, Chakrabarti S, Reboussin DM, Acton RT, Barton JC, McLaren GD, Eckfeldt JH, Dawkins FW, Gordeuk VR, Harris EL, Leiendecker-Foster C, Gossman E, Sholinsky P, Hemochromatosis and Iron Overload Screening Study Research Investigators. PMID: 16797244.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    50. Geographic and racial/ethnic differences in HFE mutation frequencies in the Hemochromatosis and Iron Overload Screening (HEIRS) Study. Ethn Dis. 2006; 16(4):815-21. Acton RT, Barton JC, Snively BM, McLaren CE, Adams PC, Harris EL, Speechley MR, McLaren GD, Dawkins FW, Leiendecker-Foster C, Holup JL, Balasubramanyam A, Hemochromatosis and Iron Overload Screening Study Research Investigators. PMID: 17061732.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    51. Iron metabolism in the hemoglobin-deficit mouse: correlation of diferric transferrin with hepcidin expression. Blood. 2006 Feb 15; 107(4):1659-64. Wilkins SJ, Frazer DM, Millard KN, McLaren GD, Anderson GJ. PMID: 16239432; PMCID: PMC1895407.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    52. Concerns in a primary care population about genetic discrimination by insurers. Genet Med. 2005 May-Jun; 7(5):311-6. Hall MA, McEwen JE, Barton JC, Walker AP, Howe EG, Reiss JA, Power TE, Ellis SD, Tucker DC, Harrison BW, McLaren GD, Ruggiero A, Thomson EJ. PMID: 15915082.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    53. Hemochromatosis and iron-overload screening in a racially diverse population. N Engl J Med. 2005 Apr 28; 352(17):1769-78. Adams PC, Reboussin DM, Barton JC, McLaren CE, Eckfeldt JH, McLaren GD, Dawkins FW, Acton RT, Harris EL, Gordeuk VR, Leiendecker-Foster C, Speechley M, Snively BM, Holup JL, Thomson E, Sholinsky P, Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators. PMID: 15858186.
      View in: PubMed   Mentions: 237     Fields:    Translation:Humans
    54. Comparison of the unsaturated iron-binding capacity with transferrin saturation as a screening test to detect C282Y homozygotes for hemochromatosis in 101,168 participants in the hemochromatosis and iron overload screening (HEIRS) study. Clin Chem. 2005 Jun; 51(6):1048-52. Adams PC, Reboussin DM, Leiendecker-Foster C, Moses GC, McLaren GD, McLaren CE, Dawkins FW, Kasvosve I, Acton RT, Barton JC, Zaccaro D, Harris EL, Press R, Chang H, Eckfeldt JH. PMID: 15833784.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsCTClinical Trials
    55. Initial screening transferrin saturation values, serum ferritin concentrations, and HFE genotypes in whites and blacks in the Hemochromatosis and Iron Overload Screening Study. Genet Test. 2005; 9(3):231-41. Barton JC, Acton RT, Dawkins FW, Adams PC, Lovato L, Leiendecker-Foster C, McLaren CE, Reboussin DM, Speechley MR, Gordeuk VR, McLaren GD, Sholinsky P, Harris EL. PMID: 16225403.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansPHPublic Health
    56. Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis. Gut. 2004 Oct; 53(10):1509-15. Frazer DM, Inglis HR, Wilkins SJ, Millard KN, Steele TM, McLaren GD, McKie AT, Vulpe CD, Anderson GJ. PMID: 15361505; PMCID: PMC1774251.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    57. Hemochromatosis and Iron Overload Screening (HEIRS) study design for an evaluation of 100,000 primary care-based adults. Am J Med Sci. 2003 Feb; 325(2):53-62. McLaren CE, Barton JC, Adams PC, Harris EL, Acton RT, Press N, Reboussin DM, McLaren GD, Sholinsky P, Walker AP, Gordeuk VR, Leiendecker-Foster C, Dawkins FW, Eckfeldt JH, Mellen BG, Speechley M, Thomson E, Hemochromatosis and Iron Overload Study Research Investigators. PMID: 12589228.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansPHPublic Health
    58. Comparison of sampling methods for obtaining accurate coagulation values in hemodialysis patients with heparinized central venous catheters. Nephrol Nurs J. 2001 Dec; 28(6):632-6. McLaren G, Hanna C, Mills L, Bourdeau J, Cowin R. PMID: 12143472.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    59. Relationship between transferrin saturation and iron stores in the African American and US Caucasian populations: analysis of data from the third National Health and Nutrition Examination Survey. Blood. 2001 Oct 15; 98(8):2345-51. McLaren CE, Li KT, Gordeuk VR, Hasselblad V, McLaren GD. PMID: 11588029.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    60. HFE genotype in patients with hemochromatosis and other liver diseases. Ann Intern Med. 2000 Feb 01; 132(3):245; author reply 246. McLaren GD. PMID: 10651611.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    61. Patient-specific analysis of sequential haematological data by multiple linear regression and mixture distribution modelling. Stat Med. 2000 Jan 15; 19(1):83-98. McLaren CE, Kambour EL, McLachlan GJ, Lukaski HC, Li X, Brittenham GM, McLaren GD. PMID: 10623915.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    62. Screening for hemochromatosis in primary care settings. Ann Intern Med. 1998 Dec 01; 129(11):962-70. McDonnell SM, Phatak PD, Felitti V, Hover A, McLaren GD. PMID: 9867749.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    63. Distribution of transferrin saturation in an Australian population: relevance to the early diagnosis of hemochromatosis. Gastroenterology. 1998 Mar; 114(3):543-9. McLaren CE, McLachlan GJ, Halliday JW, Webb SI, Leggett BA, Jazwinska EC, Crawford DH, Gordeuk VR, McLaren GD, Powell LW. PMID: 9496946.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    64. Mapping the gene for sex-linked anemia: an inherited defect of intestinal iron absorption in the mouse. Genomics. 1998 Feb 15; 48(1):34-9. Anderson GJ, Murphy TL, Cowley L, Evans BA, Halliday JW, McLaren GD. PMID: 9503013.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    65. Etiologies, consequences, and treatment of iron overload. Crit Rev Clin Lab Sci. 1994; 31(2):89-133. Gordeuk VR, McLaren GD, Samowitz W. PMID: 7917009.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    66. Regulation of intestinal iron absorption and mucosal iron kinetics in hereditary hemochromatosis. J Lab Clin Med. 1991 May; 117(5):390-401. McLaren GD, Nathanson MH, Jacobs A, Trevett D, Thomson W. PMID: 2019794.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    67. Reticuloendothelial iron stores and hereditary hemochromatosis: a paradox. J Lab Clin Med. 1989 Feb; 113(2):137-8. McLaren GD. PMID: 2915179.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    68. Control of iron absorption in hemochromatosis. Mucosal iron kinetics in vivo. Ann N Y Acad Sci. 1988; 526:185-98. McLaren GD, Nathanson MH, Jacobs A, Trevett D, Thomson W. PMID: 3389641.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    69. Computer simulation of iron absorption: regulation of mucosal and systemic iron kinetics in dogs. J Nutr. 1987 Jun; 117(6):1067-75. Nathanson MH, McLaren GD. PMID: 3598717.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    70. Hyperferremia in immunosuppressed patients with acute nonlymphocytic leukemia and the risk of infection. J Lab Clin Med. 1986 Nov; 108(5):466-72. Gordeuk VR, Brittenham GM, McLaren GD, Spagnuolo PJ. PMID: 3534124.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    71. Iron absorption in normal and iron-deficient beagle dogs: mucosal iron kinetics. Am J Physiol. 1985 Oct; 249(4 Pt 1):G439-48. Nathanson MH, Muir A, McLaren GD. PMID: 4050995.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    72. Evidence for heterogeneity in hereditary hemochromatosis. Evaluation of 174 persons in nine families. Am J Med. 1984 May; 76(5):806-14. Muir WA, McLaren GD, Braun W, Askari A. PMID: 6720728.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    73. A model of intestinal iron absorption and plasma iron kinetics: optimal parameter estimates for normal dogs. Comput Biomed Res. 1984 Feb; 17(1):55-70. Nathanson MH, McLaren GD, Saidel GM. PMID: 6697701.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    74. Arthritis of hemochromatosis. Clinical spectrum, relation to histocompatibility antigens, and effectiveness of early phlebotomy. Am J Med. 1983 Dec; 75(6):957-65. Askari AD, Muir WA, Rosner IA, Moskowitz RW, McLaren GD, Braun WE. PMID: 6650551.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    75. Iron overload disorders: natural history, pathogenesis, diagnosis, and therapy. Crit Rev Clin Lab Sci. 1983; 19(3):205-66. McLaren GD, Muir WA, Kellermeyer RW. PMID: 6373141.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    76. Arthropathy, hypouricemia and normal serum iron studies in hereditary hemochromatosis. Am J Med. 1981 Apr; 70(4):870-4. Rosner IA, Askari AD, McLaren GD, Muir A. PMID: 7211921.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    77. Antigranulocyte antibodies and deranged immune function associated with phenytoin-induced serum sickness. Am J Hematol. 1981; 10(3):277-84. Menitove JE, Rassiga AL, McLaren GD, Daniel TM, Mahmoud AA. PMID: 7246535.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    78. Iodine and goiter in children. Pediatrics. 1975 Jul; 56(1):82-90. Trowbridge FL, Matovinovic J, McLaren GD, Nichaman MZ. PMID: 1153253.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    79. Erythrocyte protoporphyrin in the detection of iron deficiency. Clin Chem. 1975 Jul; 21(8):1121-7. McLaren GD, Carpenter JT, nino HV. PMID: 1137918.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
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