James, Anthony A

InstitutionUniversity of California, Irvine
DepartmentMicrobiology and Molecular Genetics
Address1001 Health Sciences Road
CA 92697-3950
Phone(949) 824-5930, 3210
vCardDownload vCard
    Other Positions
    TitleDonald Bren Professor

    Collapse Research 
    Collapse Research Activities and Funding
    Nicking endonuclease-mediated gene drive in mosquitoes
    NIH/NIAID R21AI116433Apr 5, 2015 - Mar 31, 2017
    Role: Principal Investigator
    Pole cell isolation from the mosquitoes, Aedes aegypti and Anopheles stephensi
    NIH/NIAID R21AI078123May 15, 2008 - Apr 30, 2012
    Role: Principal Investigator
    NIH/NIAID R01AI044800Feb 1, 2000 - Jan 31, 2005
    Role: Principal Investigator
    Species-specific regulated transposition in mosquitoes
    NIH/NIAID R01AI044238Dec 1, 1998 - Nov 30, 2009
    Role: Principal Investigator
    NIH/NIAID R13AI042579Jan 1, 1998 - Dec 31, 1998
    Role: Principal Investigator
    NIH/NIAID R01AI032730May 1, 1992 - Apr 30, 1997
    Role: Principal Investigator
    Expression of Exogenous Genes in Vector Mosquitoes
    NIH/NIAID R37AI029746Sep 1, 1989 - Jun 30, 2017
    Role: Principal Investigator
    Expression of Exogenous Genes in Vector Mosquitoes
    NIH/NIAID R01AI029746Sep 1, 1989 - Jun 30, 2007
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Bottino-Rojas V, Talyuli OAC, Carrara L, Martins AJ, James A, Oliveira PL, Paiva-Silva GO. The redox-sensing gene Nrf2 affects intestinal homeostasis, insecticide resistance and Zika virus susceptibility in the mosquito Aedes aegypti. J Biol Chem. 2018 Apr 23. PMID: 29685890.
      View in: PubMed
    2. Li Z, You L, Yan D, James A, Huang Y, Tan A. Bombyx mori histone methyltransferase BmAsh2 is essential for silkworm piRNA-mediated sex determination. PLoS Genet. 2018 Feb; 14(2):e1007245. PMID: 29474354.
      View in: PubMed
    3. Carballar-Lejarazú R, James A. Population modification of Anopheline species to control malaria transmission. Pathog Glob Health. 2017 Dec; 111(8):424-435. PMID: 29385893.
      View in: PubMed
    4. Boedhoe PSW, Schmaal L, Abe Y, Alonso P, Ameis SH, Anticevic A, Arnold PD, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Bose A, Brem S, Calvo A, Calvo R, Cheng Y, Cho KIK, Ciullo V, Dallaspezia S, Denys D, Feusner JD, Fitzgerald KD, Fouche JP, Fridgeirsson EA, Gruner P, Hanna GL, Hibar DP, Hoexter MQ, Hu H, Huyser C, Jahanshad N, James A, Kathmann N, Kaufmann C, Koch K, Kwon JS, Lazaro L, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón JM, Minuzzi L, Morer A, Nakamae T, Nakao T, Narayanaswamy JC, Nishida S, Nurmi E, O'Neill J, Piacentini J, Piras F, Piras F, Reddy YCJ, Reess TJ, Sakai Y, Sato JR, Simpson HB, Soreni N, Soriano-Mas C, Spalletta G, Stevens MC, Szeszko PR, Tolin DF, van Wingen GA, Venkatasubramanian G, Walitza S, Wang Z, Yun JY, Thompson PM, Stein DJ, van den Heuvel OA. Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group. Am J Psychiatry. 2018 May 01; 175(5):453-462. PMID: 29377733.
      View in: PubMed
    5. Adelman Z, Akbari O, Bauer J, Bier E, Bloss C, Carter SR, Callender C, Denis AC, Cowhey P, Dass B, Delborne J, Devereaux M, Ellsworth P, Friedman RM, Gantz V, Gibson C, Hay BA, Hoddle M, James A, James S, Jorgenson L, Kalichman M, Marshall J, McGinnis W, Newman J, Pearson A, Quemada H, Rudenko L, Shelton A, Vinetz JM, Weisman J, Wong B, Wozniak C. Rules of the road for insect gene drive research and testing. Nat Biotechnol. 2017 Aug 08; 35(8):716-718. PMID: 28787415.
      View in: PubMed
    6. Macias VM, Jimenez AJ, Burini-Kojin B, Pledger D, Jasinskiene N, Phong CH, Chu K, Fazekas A, Martin K, Marinotti O, James A. nanos-Driven expression of piggyBac transposase induces mobilization of a synthetic autonomous transposon in the malaria vector mosquito, Anopheles stephensi. Insect Biochem Mol Biol. 2017 08; 87:81-89. PMID: 28676355.
      View in: PubMed
    7. González-López L, Carballar-Lejarazú R, Arrevillaga Boni G, Cortés-Martínez L, Cázares-Raga FE, Trujillo-Ocampo A, Rodríguez MH, James A, Hernández-Hernández FC. Lys48 ubiquitination during the intraerythrocytic cycle of the rodent malaria parasite, Plasmodium chabaudi. PLoS One. 2017; 12(6):e0176533. PMID: 28604779.
      View in: PubMed
    8. Chen S, Hou C, Bi H, Wang Y, Xu J, Li M, James A, Huang Y, Tan A. Transgenic Clustered Regularly Interspaced Short Palindromic Repeat/Cas9-Mediated Viral Gene Targeting for Antiviral Therapy of Bombyx mori Nucleopolyhedrovirus. J Virol. 2017 04 15; 91(8). PMID: 28122981.
      View in: PubMed
    9. Xu J, Chen S, Zeng B, James A, Tan A, Huang Y. Bombyx mori P-element Somatic Inhibitor (BmPSI) Is a Key Auxiliary Factor for Silkworm Male Sex Determination. PLoS Genet. 2017 Jan; 13(1):e1006576. PMID: 28103247.
      View in: PubMed
    10. Xu J, Zhan S, Chen S, Zeng B, Li Z, James A, Tan A, Huang Y. Sexually dimorphic traits in the silkworm, Bombyx mori, are regulated by doublesex. Insect Biochem Mol Biol. 2017 01; 80:42-51. PMID: 27867075.
      View in: PubMed
    11. Peng Z, Caihe L, Beckett AN, Guan Q, James A, Simons FE. rAed a 4: A New 67-kDa Aedes aegypti Mosquito Salivary Allergen for the Diagnosis of Mosquito Allergy. Int Arch Allergy Immunol. 2016; 170(3):206-10. PMID: 27603527.
      View in: PubMed
    12. Liu H, Liu T, Xie L, Wang X, Deng Y, Chen CH, James A, Chen XG. Functional analysis of Orco and odorant receptors in odor recognition in Aedes albopictus. Parasit Vectors. 2016 06 27; 9(1):363. PMID: 27350348; PMCID: PMC4924234.
    13. Huang Y, Chen Y, Zeng B, Wang Y, James A, Gurr GM, Yang G, Lin X, Huang Y, You M. CRISPR/Cas9 mediated knockout of the abdominal-A homeotic gene in the global pest, diamondback moth (Plutella xylostella). Insect Biochem Mol Biol. 2016 08; 75:98-106. PMID: 27318252.
      View in: PubMed
    14. Kojin BB, Costa-da-Silva AL, Maciel C, Henriques DA, Carvalho DO, Martin K, Marinotti O, James A, Bonaldo MC, Capurro ML. Endogenously-expressed NH2-terminus of circumsporozoite protein interferes with sporozoite invasion of mosquito salivary glands. Malar J. 2016 Mar 10; 15:153. PMID: 26964736; PMCID: PMC4785649.
    15. Gantz VM, Jasinskiene N, Tatarenkova O, Fazekas A, Macias VM, Bier E, James A. Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi. Proc Natl Acad Sci U S A. 2015 Dec 08; 112(49):E6736-43. PMID: 26598698; PMCID: PMC4679060.
    16. Chen XG, Jiang X, Gu J, Xu M, Wu Y, Deng Y, Zhang C, Bonizzoni M, Dermauw W, Vontas J, Armbruster P, Huang X, Yang Y, Zhang H, He W, Peng H, Liu Y, Wu K, Chen J, Lirakis M, Topalis P, Van Leeuwen T, Hall AB, Jiang X, Thorpe C, Mueller RL, Sun C, Waterhouse RM, Yan G, Tu ZJ, Fang X, James A. Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):E5907-15. PMID: 26483478; PMCID: PMC4640774.
    17. Alonso-Morales A, González-López L, Cázares-Raga FE, Cortés-Martínez L, Torres-Monzón JA, Gallegos-Pérez JL, Rodríguez MH, James A, Hernández-Hernández Fde L. Protein phosphorylation during Plasmodium berghei gametogenesis. Exp Parasitol. 2015 Sep; 156:49-60. PMID: 26008612; PMCID: PMC4837889.
    18. Lo E, Yewhalaw D, Zhong D, Zemene E, Degefa T, Tushune K, Ha M, Lee MC, James A, Yan G. Molecular epidemiology of Plasmodium vivax and Plasmodium falciparum malaria among Duffy-positive and Duffy-negative populations in Ethiopia. Malar J. 2015 Feb 19; 14:84. PMID: 25884875; PMCID: PMC4340780.
    19. Biedler JK, Qi Y, Pledger D, James A, Tu Z. Maternal germline-specific genes in the Asian malaria mosquito Anopheles stephensi: characterization and application for disease control. G3 (Bethesda). 2014 12 05; 5(2):157-66. PMID: 25480960; PMCID: PMC4321024.
    20. Wang Y, Tan A, Xu J, Li Z, Zeng B, Ling L, You L, Chen Y, James A, Huang Y. Site-specific, TALENs-mediated transformation of Bombyx mori. Insect Biochem Mol Biol. 2014 12; 55:26-30. PMID: 25460511.
      View in: PubMed
    21. Jiang X, Peery A, Hall AB, Sharma A, Chen XG, Waterhouse RM, Komissarov A, Riehle MM, Shouche Y, Sharakhova MV, Lawson D, Pakpour N, Arensburger P, Davidson VL, Eiglmeier K, Emrich S, George P, Kennedy RC, Mane SP, Maslen G, Oringanje C, Qi Y, Settlage R, Tojo M, Tubio JM, Unger MF, Wang B, Vernick KD, Ribeiro JM, James A, Michel K, Riehle MA, Luckhart S, Sharakhov IV, Tu Z. Genome analysis of a major urban malaria vector mosquito, Anopheles stephensi. Genome Biol. 2014 Sep 23; 15(9):459. PMID: 25244985; PMCID: PMC4195908.
    22. Costa-da-Silva AL, Marinotti O, Ribeiro JM, Silva MC, Lopes AR, Barros MS, Sá-Nunes A, Kojin BB, Carvalho E, Suesdek L, Silva-Neto MA, James A, Capurro ML. Transcriptome sequencing and developmental regulation of gene expression in Anopheles aquasalis. PLoS Negl Trop Dis. 2014 Jul; 8(7):e3005. PMID: 25033462; PMCID: PMC4102416.
    23. Franz AW, Sanchez-Vargas I, Raban RR, Black WC, James A, Olson KE. Fitness impact and stability of a transgene conferring resistance to dengue-2 virus following introgression into a genetically diverse Aedes aegypti strain. PLoS Negl Trop Dis. 2014 May; 8(5):e2833. PMID: 24810399; PMCID: PMC4014415.
    24. Chagas AC, Ramirez JL, Jasinskiene N, James A, Ribeiro JM, Marinotti O, Calvo E. Collagen-binding protein, Aegyptin, regulates probing time and blood feeding success in the dengue vector mosquito, Aedes aegypti. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):6946-51. PMID: 24778255; PMCID: PMC4024861.
    25. Marinotti O, Ngo T, Kojin BB, Chou SP, Nguyen B, Juhn J, Carballar-Lejarazú R, Marinotti PN, Jiang X, Walter MF, Tu Z, Gershon PD, James A. Integrated proteomic and transcriptomic analysis of the Aedes aegypti eggshell. BMC Dev Biol. 2014 Apr 05; 14:15. PMID: 24707823; PMCID: PMC4234484.
    26. Brown DM, Alphey LS, McKemey A, Beech C, James A. Criteria for identifying and evaluating candidate sites for open-field trials of genetically engineered mosquitoes. Vector Borne Zoonotic Dis. 2014 Apr; 14(4):291-9. PMID: 24689963; PMCID: PMC3993056.
    27. Ramsey JM, Bond JG, Macotela ME, Facchinelli L, Valerio L, Brown DM, Scott TW, James A. A regulatory structure for working with genetically modified mosquitoes: lessons from Mexico. PLoS Negl Trop Dis. 2014 Mar; 8(3):e2623. PMID: 24626164; PMCID: PMC3952825.
    28. Costa-da-Silva AL, Kojin BB, Marinotti O, James A, Capurro ML. Expression and accumulation of the two-domain odorant-binding protein AaegOBP45 in the ovaries of blood-fed Aedes aegypti. Parasit Vectors. 2013 Dec 24; 6:364. PMID: 24367904; PMCID: PMC3892079.
    29. Li J, Wang X, Zhang G, Githure JI, Yan G, James A. Genome-block expression-assisted association studies discover malaria resistance genes in Anopheles gambiae. Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51):20675-80. PMID: 24297936; PMCID: PMC3870758.
    30. Bonizzoni M, Britton M, Marinotti O, Dunn WA, Fass J, James A. Probing functional polymorphisms in the dengue vector, Aedes aegypti. BMC Genomics. 2013 Oct 29; 14:739. PMID: 24168143; PMCID: PMC4007706.
    31. Bonizzoni M, Gasperi G, Chen X, James A. The invasive mosquito species Aedes albopictus: current knowledge and future perspectives. Trends Parasitol. 2013 Sep; 29(9):460-8. PMID: 23916878; PMCID: PMC3777778.
    32. Wang MH, Marinotti O, Zhong D, James A, Walker E, Guda T, Kweka EJ, Githure J, Yan G. Gene expression-based biomarkers for Anopheles gambiae age grading. PLoS One. 2013; 8(7):e69439. PMID: 23936017; PMCID: PMC3720620.
    33. Deng Y, Yan H, Gu J, Xu J, Wu K, Tu Z, James A, Chen X. Molecular and functional characterization of odorant-binding protein genes in an invasive vector mosquito, Aedes albopictus. PLoS One. 2013; 8(7):e68836. PMID: 23935894; PMCID: PMC3720860.
    34. Gu J, Hu W, Wu J, Zheng P, Chen M, James A, Chen X, Tu Z. miRNA genes of an invasive vector mosquito, Aedes albopictus. PLoS One. 2013; 8(7):e67638. PMID: 23840875; PMCID: PMC3698096.
    35. DeGennaro M, McBride CS, Seeholzer L, Nakagawa T, Dennis EJ, Goldman C, Jasinskiene N, James A, Vosshall LB. orco mutant mosquitoes lose strong preference for humans and are not repelled by volatile DEET. Nature. 2013 Jun 27; 498(7455):487-91. PMID: 23719379; PMCID: PMC3696029.
    36. Ruiz-Veguilla M, Barrigón ML, Hernández L, Rubio JL, Gurpegui M, Sarramea F, Cervilla J, Gutiérrez B, James A, Ferrin M. Dose-response effect between cannabis use and psychosis liability in a non-clinical population: evidence from a snowball sample. J Psychiatr Res. 2013 Aug; 47(8):1036-43. PMID: 23684550.
      View in: PubMed
    37. Marinotti O, Jasinskiene N, Fazekas A, Scaife S, Fu G, Mattingly ST, Chow K, Brown DM, Alphey L, James A. Development of a population suppression strain of the human malaria vector mosquito, Anopheles stephensi. Malar J. 2013 Apr 26; 12:142. PMID: 23622561; PMCID: PMC3648444.
    38. Carballar-Lejarazú R, Jasinskiene N, James A. Exogenous gypsy insulator sequences modulate transgene expression in the malaria vector mosquito, Anopheles stephensi. Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18):7176-81. PMID: 23584017; PMCID: PMC3645527.
    39. Wang C, Xu J, Zhou X, Li J, Yan G, James A, Chen X. Strongyloidiasis: an emerging infectious disease in China. Am J Trop Med Hyg. 2013 Mar; 88(3):420-5. PMID: 23468357; PMCID: PMC3592519.
    40. Facchinelli L, Valerio L, Ramsey JM, Gould F, Walsh RK, Bond G, Robert MA, Lloyd AL, James A, Alphey L, Scott TW. Field cage studies and progressive evaluation of genetically-engineered mosquitoes. PLoS Negl Trop Dis. 2013; 7(1):e2001. PMID: 23350003; PMCID: PMC3547837.
    41. Bonizzoni M, Dunn WA, Campbell CL, Olson KE, Marinotti O, James A. Complex modulation of the Aedes aegypti transcriptome in response to dengue virus infection. PLoS One. 2012; 7(11):e50512. PMID: 23209765.
      View in: PubMed
    42. Juhn J, James A. Hybridization in situ of salivary glands, ovaries, and embryos of vector mosquitoes. J Vis Exp. 2012 Jun 28; (64). PMID: 22781778; PMCID: PMC3476388.
    43. Isaacs AT, Jasinskiene N, Tretiakov M, Thiery I, Zettor A, Bourgouin C, James A. Transgenic Anopheles stephensi coexpressing single-chain antibodies resist Plasmodium falciparum development. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):E1922-30. PMID: 22689959; PMCID: PMC3396534.
    44. Bonizzoni M, Dunn WA, Campbell CL, Olson KE, Marinotti O, James A. Strain Variation in the Transcriptome of the Dengue Fever Vector, Aedes aegypti. G3 (Bethesda). 2012 Jan; 2(1):103-14. PMID: 22384387; PMCID: PMC3276191.
    45. James S, Simmons CP, James A. Ecology. Mosquito trials. Science. 2011 Nov 11; 334(6057):771-2. PMID: 22076370.
      View in: PubMed
    46. Black WC, Alphey L, James A. Why RIDL is not SIT. Trends Parasitol. 2011 Aug; 27(8):362-70. PMID: 21659002.
      View in: PubMed
    47. Benedict MQ, James A, Collins FH. Safety of genetically modified mosquitoes. JAMA. 2011 May 25; 305(20):2069-70; author reply 2070. PMID: 21610238.
      View in: PubMed
    48. Isaacs AT, Li F, Jasinskiene N, Chen X, Nirmala X, Marinotti O, Vinetz JM, James A. Engineered resistance to Plasmodium falciparum development in transgenic Anopheles stephensi. PLoS Pathog. 2011 Apr; 7(4):e1002017. PMID: 21533066; PMCID: PMC3080844.
    49. Wise de Valdez MR, Nimmo D, Betz J, Gong HF, James A, Alphey L, Black WC. Genetic elimination of dengue vector mosquitoes. Proc Natl Acad Sci U S A. 2011 Mar 22; 108(12):4772-5. PMID: 21383140; PMCID: PMC3064365.
    50. Bonizzoni M, Dunn WA, Campbell CL, Olson KE, Dimon MT, Marinotti O, James A. RNA-seq analyses of blood-induced changes in gene expression in the mosquito vector species, Aedes aegypti. BMC Genomics. 2011 Jan 28; 12:82. PMID: 21276245; PMCID: PMC3042412.
    51. Juhn J, Naeem-Ullah U, Maciel Guedes BA, Majid A, Coleman J, Paolucci Pimenta PF, Akram W, James A, Marinotti O. Spatial mapping of gene expression in the salivary glands of the dengue vector mosquito, Aedes aegypti. Parasit Vectors. 2011 Jan 04; 4:1. PMID: 21205315; PMCID: PMC3043528.
    52. Wang MH, Marinotti O, James A, Walker E, Githure J, Yan G. Genome-wide patterns of gene expression during aging in the African malaria vector Anopheles gambiae. PLoS One. 2010 Oct 13; 5(10):e13359. PMID: 20967211; PMCID: PMC2954169.
    53. Dissanayake SN, Ribeiro JM, Wang MH, Dunn WA, Yan G, James A, Marinotti O. aeGEPUCI: a database of gene expression in the dengue vector mosquito, Aedes aegypti. BMC Res Notes. 2010 Oct 04; 3:248. PMID: 20920356; PMCID: PMC2958886.
    54. Wu JY, Lun ZR, James A, Chen XG. Dengue Fever in mainland China. Am J Trop Med Hyg. 2010 Sep; 83(3):664-71. PMID: 20810836; PMCID: PMC2929067.
    55. Moreno M, Marinotti O, Krzywinski J, Tadei WP, James A, Achee NL, Conn JE. Complete mtDNA genomes of Anopheles darlingi and an approach to anopheline divergence time. Malar J. 2010 May 14; 9:127. PMID: 20470395; PMCID: PMC2877063.
    56. Amenya DA, Chou W, Li J, Yan G, Gershon PD, James A, Marinotti O. Proteomics reveals novel components of the Anopheles gambiae eggshell. J Insect Physiol. 2010 Oct; 56(10):1414-9. PMID: 20433845; PMCID: PMC2918668.
    57. Lavery JV, Tinadana PO, Scott TW, Harrington LC, Ramsey JM, Ytuarte-Nuñez C, James A. Towards a framework for community engagement in global health research. Trends Parasitol. 2010 Jun; 26(6):279-83. PMID: 20299285.
      View in: PubMed
    58. Luckhart S, Lindsay SW, James A, Scott TW. Reframing critical needs in vector biology and management of vector-borne disease. PLoS Negl Trop Dis. 2010 Feb 23; 4(2):e566. PMID: 20186276; PMCID: PMC2826393.
    59. Fu G, Lees RS, Nimmo D, Aw D, Jin L, Gray P, Berendonk TU, White-Cooper H, Scaife S, Kim Phuc H, Marinotti O, Jasinskiene N, James A, Alphey L. Female-specific flightless phenotype for mosquito control. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4550-4. PMID: 20176967; PMCID: PMC2826341.
    60. Nguyen TV, Sacci JB, de la Vega P, John CC, James A, Kang AS. Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB2 in malaria exposed individuals. Malar J. 2009 Oct 23; 8:235. PMID: 19852802; PMCID: PMC2772840.
    61. Beaty BJ, Prager DJ, James A, Jacobs-Lorena M, Miller LH, Law JH, Collins FH, Kafatos FC. From Tucson to genomics and transgenics: the vector biology network and the emergence of modern vector biology. PLoS Negl Trop Dis. 2009; 3(3):e343. PMID: 19333394; PMCID: PMC2659576.
    62. Sieglaff DH, Dunn WA, Xie XS, Megy K, Marinotti O, James A. Comparative genomics allows the discovery of cis-regulatory elements in mosquitoes. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):3053-8. PMID: 19211788; PMCID: PMC2640218.
    63. Terenius O, Marinotti O, Sieglaff D, James A. Molecular genetic manipulation of vector mosquitoes. Cell Host Microbe. 2008 Nov 13; 4(5):417-23. PMID: 18996342; PMCID: PMC2656434.
    64. Terenius O, de Oliveira CD, Pinheiro WD, Tadei WP, James A, Marinotti O. 16S rRNA gene sequences from bacteria associated with adult Anopheles darlingi (Diptera: Culicidae) mosquitoes. J Med Entomol. 2008 Jan; 45(1):172-5. PMID: 18283961.
      View in: PubMed
    65. Chen XG, Mathur G, James A. Gene expression studies in mosquitoes. Adv Genet. 2008; 64:19-50. PMID: 19161831; PMCID: PMC2798853.
    66. Coleman J, Juhn J, James A. Dissection of midgut and salivary glands from Ae. aegypti mosquitoes. J Vis Exp. 2007; (5):228. PMID: 18979026; PMCID: PMC2557086.
    67. James A. Preventing the spread of malaria and dengue fever using genetically modified mosquitoes. J Vis Exp. 2007; (5):231. PMID: 18979028; PMCID: PMC2557084.
    68. Terenius O, Juhn J, James A. Injection of An. stephensi embryos to generate malaria-resistant mosquitoes. J Vis Exp. 2007; (5):216. PMID: 18979016; PMCID: PMC2557085.
    69. Jasinskiene N, Juhn J, James A. Microinjection of A. aegypti embryos to obtain transgenic mosquitoes. J Vis Exp. 2007; (5):219. PMID: 18979017; PMCID: PMC2557089.
    70. Luna BM, Juhn J, James A. Injection of dsRNA into female A. aegypti mosquitos. J Vis Exp. 2007; (5):215. PMID: 18979015; PMCID: PMC2557097.
    71. Adelman ZN, Jasinskiene N, Onal S, Juhn J, Ashikyan A, Salampessy M, MacCauley T, James A. nanos gene control DNA mediates developmentally regulated transposition in the yellow fever mosquito Aedes aegypti. Proc Natl Acad Sci U S A. 2007 Jun 12; 104(24):9970-5. PMID: 17548819; PMCID: PMC1891237.
    72. Jasinskiene N, Coleman J, Ashikyan A, Salampessy M, Marinotti O, James A. Genetic control of malaria parasite transmission: threshold levels for infection in an avian model system. Am J Trop Med Hyg. 2007 Jun; 76(6):1072-8. PMID: 17556613.
      View in: PubMed
    73. Chen XG, Marinotti O, Whitman L, Jasinskiene N, James A, Romans P. The Anopheles gambiae vitellogenin gene (VGT2) promoter directs persistent accumulation of a reporter gene product in transgenic Anopheles stephensi following multiple bloodmeals. Am J Trop Med Hyg. 2007 Jun; 76(6):1118-24. PMID: 17556621.
      View in: PubMed
    74. Li JS, Han Q, Fang J, Rizzi M, James A, Li J. Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation. Arch Insect Biochem Physiol. 2007 Feb; 64(2):74-87. PMID: 17212352; PMCID: PMC2565576.
    75. Nirmala X, Marinotti O, Sandoval JM, Phin S, Gakhar S, Jasinskiene N, James A. Functional characterization of the promoter of the vitellogenin gene, AsVg1, of the malaria vector, Anopheles stephensi. Insect Biochem Mol Biol. 2006 Sep; 36(9):694-700. PMID: 16935218.
      View in: PubMed
    76. Dissanayake SN, Marinotti O, Ribeiro JM, James A. angaGEDUCI: Anopheles gambiae gene expression database with integrated comparative algorithms for identifying conserved DNA motifs in promoter sequences. BMC Genomics. 2006 May 17; 7:116. PMID: 16707020; PMCID: PMC1524951.
    77. Sun D, McNicol A, James A, Peng Z. Expression of functional recombinant mosquito salivary apyrase: a potential therapeutic platelet aggregation inhibitor. Platelets. 2006 May; 17(3):178-84. PMID: 16702045.
      View in: PubMed
    78. LaCrue AN, Sivaguru M, Walter MF, Fidock DA, James A, Beerntsen BT. A ubiquitous Plasmodium protein displays a unique surface labeling pattern in sporozoites. Mol Biochem Parasitol. 2006 Aug; 148(2):199-209. PMID: 16697061.
      View in: PubMed
    79. Marinotti O, Capurro Mde L, Nirmala X, Calvo E, James A. Structure and expression of the lipophorin-encoding gene of the malaria vector, Anopheles gambiae. Comp Biochem Physiol B Biochem Mol Biol. 2006 May; 144(1):101-9. PMID: 16524752.
      View in: PubMed
    80. Franz AW, Sanchez-Vargas I, Adelman ZN, Blair CD, Beaty BJ, James A, Olson KE. Engineering RNA interference-based resistance to dengue virus type 2 in genetically modified Aedes aegypti. Proc Natl Acad Sci U S A. 2006 Mar 14; 103(11):4198-203. PMID: 16537508; PMCID: PMC1449670.
    81. Schneider DS, James A. Bridging the gaps in vector biology. Workshop on the Molecular and Population Biology of Mosquitoes and other Disease Vectors. EMBO Rep. 2006 Mar; 7(3):259-62. PMID: 16485025; PMCID: PMC1456880.
    82. Feitosa FM, Calvo E, Merino EF, Durham AM, James A, de Bianchi AG, Marinotti O, Capurro ML. A transcriptome analysis of the Aedes aegypti vitellogenic fat body. J Insect Sci. 2006; 6:1-26. PMID: 19537968; PMCID: PMC2990292.
    83. Lacrue AN, James A, Beerntsen BT. The novel Plasmodium gallinaceum sporozoite protein, Pg93, is preferentially expressed in the nucleus of oocyst sporozoites. Am J Trop Med Hyg. 2005 Sep; 73(3):634-43. PMID: 16172495.
      View in: PubMed
    84. Li B, Calvo E, Marinotti O, James A, Paskewitz SM. Characterization of the c-type lysozyme gene family in Anopheles gambiae. Gene. 2005 Nov 07; 360(2):131-9. PMID: 16137842.
      View in: PubMed
    85. Calvo E, Walter M, Adelman ZN, Jimenez A, Onal S, Marinotti O, James A. Nanos (nos) genes of the vector mosquitoes, Anopheles gambiae, Anopheles stephensi and Aedes aegypti. Insect Biochem Mol Biol. 2005 Jul; 35(7):789-98. PMID: 15894194.
      View in: PubMed
    86. James A. Gene drive systems in mosquitoes: rules of the road. Trends Parasitol. 2005 Feb; 21(2):64-7. PMID: 15664528.
      View in: PubMed
    87. Chen H, Wang J, Liang P, Karsay-Klein M, James A, Brazeau D, Yan G. Microarray analysis for identification of Plasmodium-refractoriness candidate genes in mosquitoes. Genome. 2004 Dec; 47(6):1061-70. PMID: 15644964.
      View in: PubMed
    88. Adelman ZN, Jasinskiene N, Vally KJ, Peek C, Travanty EA, Olson KE, Brown SE, Stephens JL, Knudson DL, Coates CJ, James A. Formation and loss of large, unstable tandem arrays of the piggyBac transposable element in the yellow fever mosquito, Aedes aegypti. Transgenic Res. 2004 Oct; 13(5):411-25. PMID: 15587266.
      View in: PubMed
    89. Travanty EA, Adelman ZN, Franz AW, Keene KM, Beaty BJ, Blair CD, James A, Olson KE. Using RNA interference to develop dengue virus resistance in genetically modified Aedes aegypti. Insect Biochem Mol Biol. 2004 Jul; 34(7):607-13. PMID: 15242701.
      View in: PubMed
    90. Romero LC, Nguyen TV, Deville B, Ogunjumo O, James A. The MB2 gene family of Plasmodium species has a unique combination of S1 and GTP-binding domains. BMC Bioinformatics. 2004 Jun 28; 5:83. PMID: 15222903; PMCID: PMC482805.
    91. Jasinskiene N, Coates CJ, Ashikyan A, James A. High efficiency, site-specific excision of a marker gene by the phage P1 cre-loxP system in the yellow fever mosquito, Aedes aegypti. Nucleic Acids Res. 2003 Nov 15; 31(22):e147. PMID: 14602940; PMCID: PMC275584.
    92. James A. Blocking malaria parasite invasion of mosquito salivary glands. J Exp Biol. 2003 Nov; 206(Pt 21):3817-21. PMID: 14506217.
      View in: PubMed
    93. O'Brochta DA, Sethuraman N, Wilson R, Hice RH, Pinkerton AC, Levesque CS, Bideshi DK, Jasinskiene N, Coates CJ, James A, Lehane MJ, Atkinson PW. Gene vector and transposable element behavior in mosquitoes. J Exp Biol. 2003 Nov; 206(Pt 21):3823-34. PMID: 14506218.
      View in: PubMed
    94. Nirmala X, James A. Engineering Plasmodium-refractory phenotypes in mosquitoes. Trends Parasitol. 2003 Sep; 19(9):384-7. PMID: 12957511.
      View in: PubMed
    95. Malafronte Rdos S, Calvo E, James A, Marinotti O. The major salivary gland antigens of Culex quinquefasciatus are D7-related proteins. Insect Biochem Mol Biol. 2003 Jan; 33(1):63-71. PMID: 12459201.
      View in: PubMed
    96. Alphey L, Beard CB, Billingsley P, Coetzee M, Crisanti A, Curtis C, Eggleston P, Godfray C, Hemingway J, Jacobs-Lorena M, James A, Kafatos FC, Mukwaya LG, Paton M, Powell JR, Schneider W, Scott TW, Sina B, Sinden R, Sinkins S, Spielman A, Touré Y, Collins FH. Malaria control with genetically manipulated insect vectors. Science. 2002 Oct 04; 298(5591):119-21. PMID: 12364786.
      View in: PubMed
    97. James A. Engineering mosquito resistance to malaria parasites: the avian malaria model. Insect Biochem Mol Biol. 2002 Oct; 32(10):1317-23. PMID: 12225922.
      View in: PubMed
    98. Adelman ZN, Jasinskiene N, James A. Development and applications of transgenesis in the yellow fever mosquito, Aedes aegypti. Mol Biochem Parasitol. 2002 Apr 30; 121(1):1-10. PMID: 11985858.
      View in: PubMed
    99. Atkinson PW, James A. Germline transformants spreading out to many insect species. Adv Genet. 2002; 47:49-86. PMID: 12000097.
      View in: PubMed
    100. Fidock DA, Nguyen TV, Beerntsen BT, James A. Production of stage-specific Plasmodium falciparum cDNA libraries using subtractive hybridization. Methods Mol Med. 2002; 72:277-89. PMID: 12125125.
      View in: PubMed
    101. James A. What's that buzz? Mosquitoes and fruit flies commingle. Parasitol Today. 2000 Dec; 16(12):503-4. PMID: 11121841.
      View in: PubMed
    102. James A, Beerntsen BT, Capurro Mde L, Coates CJ, Coleman J, Jasinskiene N, Krettli AU. Controlling malaria transmission with genetically-engineered, Plasmodium-resistant mosquitoes: milestones in a model system. Parassitologia. 1999 Sep; 41(1-3):461-71. PMID: 10697903.
      View in: PubMed
    Anthony's Networks
    Derived automatically from this person's publications.
    People in Profiles who have published with this person.
    Related Authors
    People who share related concepts with this person.