Alvin Yu

Title(s)	Assistant Professor, Physiology and Biophysics
School	School of Medicine
Address	1001 Health Sciences Road Irvine CA 92697-3950
Phone	(949) 824-4643
ORCID	0000-0002-8051-7661
vCard	Download vCard

Overview

Interests

multiscale simulations, molecular modeling, viruses, HIV, ion channels, proteins, computational biophysics

Websites

Lab Website

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Phosphorylation at Ser65 modulates ubiquitin conformational dynamics. Structure. 2023 07 06; 31(7):884-890.e2. Yovanno RA, Yu A, Wied TJ, Lau AY. PMID: 37267945; PMCID: PMC10330661.

View in: PubMed Mentions: Fields:
Bio Biochemistry Bio Biotechnology Mol Molecular Biology
Translation:Cells
Strain and rupture of HIV-1 capsids during uncoating. Proc Natl Acad Sci U S A. 2022 03 08; 119(10):e2117781119. Yu A, Lee EMY, Briggs JAG, Ganser-Pornillos BK, Pornillos O, Voth GA. PMID: 35238630; PMCID: PMC8915963.

View in: PubMed Mentions: 10 Fields:
Sci Science
Translation:Humans Cells
Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core. Nat Commun. 2022 02 22; 13(1):1002. Pak AJ, Yu A, Ke Z, Briggs JAG, Voth GA. PMID: 35194049; PMCID: PMC8863989.

View in: PubMed Mentions: 18 Fields:
Bio Biology Sci Science
Translation:Humans Cells
Stability and molecular pathways to the formation of spin defects in silicon carbide. Nat Commun. 2021 Nov 03; 12(1):6325. Lee EMY, Yu A, de Pablo JJ, Galli G. PMID: 34732705; PMCID: PMC8566517.

View in: PubMed Mentions: 3 Fields:
Bio Biology Sci Science
Integrin-based mechanosensing through conformational deformation. Biophys J. 2021 10 19; 120(20):4349-4359. Driscoll TP, Bidone TC, Ahn SJ, Yu A, Groisman A, Voth GA, Schwartz MA. PMID: 34509509; PMCID: PMC8553792.

View in: PubMed Mentions: 5 Fields:
Bio Biophysics
Translation:Cells
Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core. bioRxiv. 2021 Jun 07. Pak AJ, Yu A, Ke Z, Briggs JAG, Voth GA. PMID: 34127973; PMCID: PMC8202425.

View in: PubMed Mentions:
A multiscale coarse-grained model of the SARS-CoV-2 virion. Biophys J. 2021 03 16; 120(6):1097-1104. Yu A, Pak AJ, He P, Monje-Galvan V, Casalino L, Gaieb Z, Dommer AC, Amaro RE, Voth GA. PMID: 33253634; PMCID: PMC7695975.

View in: PubMed Mentions: 56 Fields:
Bio Biophysics
Translation:Cells
Temperature and Phase Transferable Bottom-up Coarse-Grained Models. J Chem Theory Comput. 2020 Nov 10; 16(11):6823-6842. Jin J, Yu A, Voth GA. PMID: 32975948; PMCID: PMC8631167.

View in: PubMed Mentions: 11 Fields:
Bio Biochemistry Che Chemistry
A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion. bioRxiv. 2020 Oct 02. Yu A, Pak AJ, He P, Monje-Galvan V, Casalino L, Gaieb Z, Dommer AC, Amaro RE, Voth GA. PMID: 33024966; PMCID: PMC7536869.

View in: PubMed Mentions:
Atomic-scale characterization of mature HIV-1 capsid stabilization by inositol hexakisphosphate (IP6). Sci Adv. 2020 09; 6(38). Yu A, Lee EMY, Jin J, Voth GA. PMID: 32938668; PMCID: PMC7494349.

View in: PubMed Mentions: 18 Fields:
Sci Science
TRIM5α self-assembly and compartmentalization of the HIV-1 viral capsid. Nat Commun. 2020 03 11; 11(1):1307. Yu A, Skorupka KA, Pak AJ, Ganser-Pornillos BK, Pornillos O, Voth GA. PMID: 32161265; PMCID: PMC7066149.

View in: PubMed Mentions: 28 Fields:
Bio Biology Sci Science
Translation:Humans Cells
Off-Pathway Assembly: A Broad-Spectrum Mechanism of Action for Drugs That Undermine Controlled HIV-1 Viral Capsid Formation. J Am Chem Soc. 2019 07 03; 141(26):10214-10224. Pak AJ, Grime JMA, Yu A, Voth GA. PMID: 31244184; PMCID: PMC6739737.

View in: PubMed Mentions: 18 Fields:
Che Chemistry
Translation:Humans Cells
Glutamate and Glycine Binding to the NMDA Receptor. Structure. 2018 07 03; 26(7):1035-1043.e2. Yu A, Lau AY. PMID: 29887499; PMCID: PMC6031449.

View in: PubMed Mentions: 24 Fields:
Bio Biochemistry Bio Biotechnology Mol Molecular Biology
Translation:Humans Animals Cells
Neurotransmitter Funneling Optimizes Glutamate Receptor Kinetics. Neuron. 2018 01 03; 97(1):139-149.e4. Yu A, Salazar H, Plested AJR, Lau AY. PMID: 29249286; PMCID: PMC5766834.

View in: PubMed Mentions: 9 Fields:
Neu Neurology
Translation:Humans Cells
Energetics of Glutamate Binding to an Ionotropic Glutamate Receptor. J Phys Chem B. 2017 11 22; 121(46):10436-10442. Yu A, Lau AY. PMID: 29065265; PMCID: PMC5716343.

View in: PubMed Mentions: 10 Fields:
Che Chemistry
Translation:Humans Cells
Molecular lock regulates binding of glycine to a primitive NMDA receptor. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):E6786-E6795. Yu A, Alberstein R, Thomas A, Zimmet A, Grey R, Mayer ML, Lau AY. PMID: 27791085; PMCID: PMC5098608.

View in: PubMed Mentions: 19 Fields:
Sci Science
Translation:Humans Animals Cells