Sean Emmanuel Stephane Coeckelenbergh

Title(s)Assistant Health Sciences Professor, Anesthesiology and Perioperative Care
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-5501
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    1. Assisted Fluid Management and Sublingual Microvascular Flow During High-Risk Abdominal Surgery: A Randomized Controlled Trial. Anesth Analg. 2024 Aug 08. Coeckelenbergh S, Entzeroth M, Van der Linden P, Flick M, Soucy-Proulx M, Alexander B, Rinehart J, Grogan T, Cannesson M, Vincent JL, Vicaut E, Duranteau J, Joosten A. PMID: 39116013.
      View in: PubMed   Mentions:    Fields:    
    2. Restrictive versus Decision Support Guided Fluid Therapy During Major Hepatic Resection Surgery: A Randomized Controlled Trial. Anesthesiology. 2024 Jul 25. Coeckelenbergh S, Proux-Soucy M, Van der Linden P, Roullet S, Moussa M, Kato H, Toubal L, Naili S, Rinehart J, Grogan T, Cannesson M, Duranteau J, Joosten A. PMID: 39052844.
      View in: PubMed   Mentions:    Fields:    
    3. Effects of opioid-based versus opioid-free anaesthesia on blinded nociception level index values during laparoscopic gastric bypass surgery: a secondary analysis of a randomised double-blind trial. BJA Open. 2024 Sep; 11:100295. Coeckelenbergh S, Oltean T, Dandrifosse AC, Clanet M, Joosten A. PMID: 39021872; PMCID: PMC11252597.
      View in: PubMed   Mentions:
    4. Effect of opioid-free versus opioid-based strategies during multimodal anaesthesia on postoperative morphine consumption after bariatric surgery: a randomised double-blind clinical trial. BJA Open. 2024 Mar; 9:100263. Clanet M, Touihri K, El Haddad C, Goldsztejn N, Himpens J, Fils JF, Gricourt Y, Van der Linden P, Coeckelenbergh S, Joosten A, Dandrifosse AC. PMID: 38435809; PMCID: PMC10906147.
      View in: PubMed   Mentions: 2  
    5. Control of mean arterial pressure using a closed-loop system for norepinephrine infusion in severe brain injury patients: the COMAT randomized controlled trial. J Clin Monit Comput. 2024 02; 38(1):25-30. Joosten A, Rinehart J, Cannesson M, Coeckelenbergh S, Pochard J, Vicaut E, Duranteau J. PMID: 38310591.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Sonorheometry Device Thresholds in Liver Transplantation: An Observational Retrospective Study. J Clin Med. 2024 Jan 25; 13(3). Soucy-Proulx M, Kato H, Coeckelenbergh S, Naili Kortaia S, Herboulier L, Pittau G, Pham P, Lemoine A, Duranteau J, Roullet S. PMID: 38337389; PMCID: PMC10856129.
      View in: PubMed   Mentions:
    7. Perioperative Fluid and Vasopressor Therapy in 2050: From Experimental Medicine to Personalization Through Automation. Anesth Analg. 2024 Feb 01; 138(2):284-294. Coeckelenbergh S, Vincent JL, Duranteau J, Joosten A, Rinehart J. PMID: 38215708.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Closed-loop anesthesia: foundations and applications in contemporary perioperative medicine. J Clin Monit Comput. 2024 Apr; 38(2):487-504. Coeckelenbergh S, Boelefahr S, Alexander B, Perrin L, Rinehart J, Joosten A, Barvais L. PMID: 38184504.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Intraoperative hypotension and postoperative outcomes. Comment on Br J Anaesth 2023; 131: 823-831. Br J Anaesth. 2024 Mar; 132(3):616-618. Patricio D, Boelefahr S, Coeckelenbergh S. PMID: 38177008.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Smartphone-Based versus Non-Invasive Automatic Oscillometric Brachial Cuff Blood Pressure Measurements: A Prospective Method Comparison Volunteer Study. J Pers Med. 2023 Dec 21; 14(1). Delmotte L, Desebbe O, Alexander B, Kouz K, Coeckelenbergh S, Schoettker P, Turgay T, Joosten A. PMID: 38276230; PMCID: PMC10817276.
      View in: PubMed   Mentions:
    11. Tight control of mean arterial pressure using a closed loop system for norepinephrine infusion after high-risk abdominal surgery: a randomized controlled trial. J Clin Monit Comput. 2024 02; 38(1):19-24. Coeckelenbergh S, Soucy-Proulx M, Van der Linden P, Clanet M, Rinehart J, Cannesson M, Duranteau J, Joosten A. PMID: 38108944; PMCID: PMC11323032.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Closing the loop: automation in anesthesiology is coming. J Clin Monit Comput. 2024 02; 38(1):1-4. Coeckelenbergh S, Joosten A, Cannesson M, Rinehart J. PMID: 37707703.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial. Comment on Br J Anaesth 2023; 131: 253-65. Br J Anaesth. 2023 10; 131(4):e142-e143. Coeckelenbergh S, Soucy-Proulx M, Radtke FM. PMID: 37541950.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Nociception level index-guided antinociception versus routine care during remifentanil-propofol anaesthesia for moderate-to-high risk cardiovascular surgery: A randomized trial. Eur J Anaesthesiol. 2023 10 01; 40(10):790-793. Coeckelenbergh S, Sessler DI, Doria S, Patricio D, Jaubert L, Huybrechts I, Stefanidis C, Kapessidou P, Tuna T, Engelman E, Barvais L, Perrin L. PMID: 37497778.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Physiological Modeling of Hemodynamic Responses to Sodium Nitroprusside. J Pers Med. 2023 Jul 06; 13(7). Rinehart J, Coeckelenbergh S, Srivastava I, Cannesson M, Joosten A. PMID: 37511714; PMCID: PMC10381667.
      View in: PubMed   Mentions:
    16. Arterial Lactate Concentration at the End of Liver Transplantation is Independently Associated With One-Year Mortality. Transplant Proc. 2023 Jan-Feb; 55(1):147-152. Coeckelenbergh S, Drouard L, Ickx B, Lucidi V, Germanova D, Desebbe O, Duhaut L, Moussa M, Naili S, Vibert E, Samuel D, Duranteau J, Vincent JL, Rinehart J, Van der Linden P, Joosten A. PMID: 36623962.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Intraoperative measurement of the respiratory exchange ratio predicts postoperative complications after liver transplantation. BMC Anesthesiol. 2022 12 28; 22(1):405. Coeckelenbergh S, Desebbe O, Carrier FM, Thepault F, De Oliveira C, Pellerin F, Le Canne C, Herboulier L, Laukaityte E, Moussa M, Toubal L, Kato H, Pham H, Roullet S, Lanteri Minet M, Amara Y, Naili S, Ciacio O, Cherqui D, Duranteau J, Vincent JL, Van der Linden P, Joosten A. PMID: 36577954; PMCID: PMC9795787.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Predicting personalised remifentanil effect site concentration for surgical incision using the nociception level index: A prospective calibration and validation study. Eur J Anaesthesiol. 2022 12 01; 39(12):918-927. Perrin L, Bisdorff M, Saxena S, Tabolcea I, Huybrechts I, Van Obbergh L, Engelman E, Barvais L, Coeckelenbergh S. PMID: 36125017.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    19. Systolic Arterial Pressure Control Using an Automated Closed-Loop System for Vasopressor Infusion during Intermediate-to-High-Risk Surgery: A Feasibility Study. J Pers Med. 2022 Sep 21; 12(10). Rinehart J, Desebbe O, Berna A, Lam I, Coeckelenbergh S, Cannesson M, Joosten A. PMID: 36294696; PMCID: PMC9604572.
      View in: PubMed   Mentions: 4  
    20. Response to: Should we infuse more fluids in liver resection? Eur J Anaesthesiol. 2022 09 01; 39(9):790-791. Coeckelenbergh S, Van der Linden P, Joosten A. PMID: 35919029.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Assessing the discriminative ability of the respiratory exchange ratio to detect hyperlactatemia during intermediate-to-high risk abdominal surgery. BMC Anesthesiol. 2022 07 08; 22(1):211. Karam L, Desebbe O, Coeckelenbergh S, Alexander B, Colombo N, Laukaityte E, Pham H, Lanteri Minet M, Toubal L, Moussa M, Naili S, Duranteau J, Vincent JL, Van der Linden P, Joosten A. PMID: 35804321; PMCID: PMC9264511.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Impact of conventional vs. goal-directed fluid therapy on urethral tissue perfusion in patients undergoing liver surgery: A pilot randomised controlled trial. Eur J Anaesthesiol. 2022 04 01; 39(4):324-332. Chirnoaga D, Coeckelenbergh S, Ickx B, Van Obbergh L, Lucidi V, Desebbe O, Carrier FM, Michard F, Vincent JL, Duranteau J, Van der Linden P, Joosten A. PMID: 34669645.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Opioid-sparing strategies and their link to postoperative morphine and antiemetic administration: a retrospective study. Br J Anaesth. 2022 03; 128(3):e242-e245. Coeckelenbergh S, Le Corre P, De Baerdemaeker L, Bougerol A, Wouters P, Engelman E, Estebe JP. PMID: 35067367.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Current trends in anesthetic depth and antinociception monitoring: an international survey. J Clin Monit Comput. 2022 10; 36(5):1407-1422. Coeckelenbergh S, Richebé P, Longrois D, Joosten A, De Hert S. PMID: 34826017.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Long-Term Outcome After Venoarterial Extracorporeal Membrane Oxygenation as Bridge to Left Ventricular Assist Device Preceding Heart Transplantation. J Cardiothorac Vasc Anesth. 2022 06; 36(6):1694-1702. Coeckelenbergh S, Valente F, Mortier J, Engelman E, Roussoulières A, El Oumeiri B, Antoine M, Van Obbergh L, Taccone FS, Vanden Eynden F, Stefanidis C. PMID: 34330577.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception: A randomised controlled trial. Eur J Anaesthesiol. 2021 05 01; 38(5):524-533. Coeckelenbergh S, Doria S, Patricio D, Perrin L, Engelman E, Rodriguez A, Di Marco L, Van Obbergh L, Estebe JP, Barvais L, Kapessidou P. PMID: 33259449.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    27. Nociception level-guided fentanyl titration: potential impact of multimodal anaesthesia and false positives. Comment on Br J Anaesth 2020; 125: 1070-8. Br J Anaesth. 2021 02; 126(2):e64-e65. Coeckelenbergh S, Vereecke HEM, Richebé P. PMID: 33250181.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. [Guiding opioid-free intravenous antinociception with the Analgesia Nociception Index: a case report]. Braz J Anesthesiol. 2020 Nov-Dec; 70(6):678-681. Coeckelenbergh S, Estebe JP. PMID: 33279229; PMCID: PMC9373240.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Hydroxyethyl starch for perioperative goal-directed fluid therapy in 2020: a narrative review. BMC Anesthesiol. 2020 08 20; 20(1):209. Joosten A, Coeckelenbergh S, Alexander B, Delaporte A, Cannesson M, Duranteau J, Saugel B, Vincent JL, Van der Linden P. PMID: 32819296; PMCID: PMC7441629.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    30. Ankle blood pressure is not a reliable surrogate for brachial blood pressure in young healthy patients undergoing general anaesthesia: A prospective observational cohort study. Eur J Anaesthesiol. 2020 Jul; 37(7):611-614. Coeckelenbergh S, Plasman C, Fils JF, Schmartz D, Van der Linden P. PMID: 32516179.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Feasibility of computer-assisted vasopressor infusion using continuous non-invasive blood pressure monitoring in high-risk patients undergoing renal transplant surgery. Anaesth Crit Care Pain Med. 2020 10; 39(5):623-624. Joosten A, Coeckelenbergh S, Alexander B, Cannesson M, Rinehart J. PMID: 32268211; PMCID: PMC8104119.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    32. Automated systems for perioperative goal-directed hemodynamic therapy. J Anesth. 2020 02; 34(1):104-114. Coeckelenbergh S, Zaouter C, Alexander B, Cannesson M, Rinehart J, Duranteau J, Van der Linden P, Joosten A. PMID: 31555916.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    33. Sepsis is frequent in initially non-critical hypotensive emergency department patients and is associated with increased mortality. Am J Emerg Med. 2019 12; 37(12):2242-2245. Coeckelenbergh S, Van Nuffelen M, Mélot C. PMID: 31466913.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. Personalized Versus Protocolized Fluid Management Using Noninvasive Hemodynamic Monitoring (Clearsight System) in Patients Undergoing Moderate-Risk Abdominal Surgery. Anesth Analg. 2019 07; 129(1):e8-e12. Joosten A, Raj Lawrence S, Colesnicenco A, Coeckelenbergh S, Vincent JL, Van der Linden P, Cannesson M, Rinehart J. PMID: 29878939.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    35. Reply to: implementation of closed-loop-assisted intra-operative goal-directed fluid therapy during surgery. Eur J Anaesthesiol. 2019 04; 36(4):304-305. Coeckelenbergh S, Van der Linden P, Rinehart J, Joosten A. PMID: 30817362.
      View in: PubMed   Mentions: 1     Fields:    
    36. Pleth variability index versus pulse pressure variation for intraoperative goal-directed fluid therapy in patients undergoing low-to-moderate risk abdominal surgery: a randomized controlled trial. BMC Anesthesiol. 2019 03 09; 19(1):34. Coeckelenbergh S, Delaporte A, Ghoundiwal D, Bidgoli J, Fils JF, Schmartz D, Van der Linden P. PMID: 30851740; PMCID: PMC6408844.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    37. Synchronized mandibular movement and capnography: a novel approach to obstructive airway detection during procedural sedation-a post hoc analysis of a prospective study. J Clin Monit Comput. 2019 Dec; 33(6):1065-1070. Ponthieu N, Coeckelenbergh S, Engelman E, Tuna T, Van Obbergh L, Barvais L. PMID: 30610518.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    38. Implementation of closed-loop-assisted intra-operative goal-directed fluid therapy during major abdominal surgery: A case-control study with propensity matching. Eur J Anaesthesiol. 2018 09; 35(9):650-658. Joosten A, Coeckelenbergh S, Delaporte A, Ickx B, Closset J, Roumeguere T, Barvais L, Van Obbergh L, Cannesson M, Rinehart J, Van der Linden P. PMID: 29750699.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    39. Neostigmine accelerates recovery from moderate mivacurium neuromuscular block independently of train-of-four count at injection: a randomised controlled trial. Br J Anaesth. 2018 Aug; 121(2):497-499. Nicolardot J, Engelman E, Coeckelenbergh S, Jungels C, Baurain M. PMID: 30032892.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
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