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Brenner, Matthew

TitleProfessor
InstitutionUniversity of California, Irvine
DepartmentMedicine
Address1001 Health Sciences Road
CA 92697-3950
Phone(714) 456-6776
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    Collapse Research 
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    High Resolution Optical Coherence Tomography for Early Airway Cancer Detection
    NIH/NCI R01CA124967Aug 13, 2007 - Jan 31, 2013
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lee J, Rockwood G, Logue B, Manandhar E, Petrikovics I, Han C, Bebarta V, Mahon SB, Burney T, Brenner M. Monitoring Dose Response of Cyanide Antidote Dimethyl Trisulfide in Rabbits Using Diffuse Optical Spectroscopy. J Med Toxicol. 2018 Aug 09. PMID: 30094773.
      View in: PubMed
    2. Miao Y, Jing JC, Desai V, Mahon SB, Brenner M, Veress LA, White CW, Chen Z. Automated 3D segmentation of methyl isocyanate-exposed rat trachea using an ultra-thin, fully fiber optic optical coherence endoscopic probe. Sci Rep. 2018 Jun 07; 8(1):8713. PMID: 29880863.
      View in: PubMed
    3. Sips PY, Shi X, Musso G, Nath AK, Zhao Y, Nielson J, Morningstar J, Kelly AE, Mikell B, Buys E, Bebarta V, Rutter J, Davisson VJ, Mahon S, Brenner M, Boss GR, Peterson RT, Gerszten RE, MacRae CA. Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning. PLoS One. 2018; 13(6):e0193889. PMID: 29879736.
      View in: PubMed
    4. Ghijsen M, Lentsch GR, Gioux S, Brenner M, Durkin AJ, Choi B, Tromberg BJ. Quantitative real-time optical imaging of the tissue metabolic rate of oxygen consumption. J Biomed Opt. 2018 Mar; 23(3):1-12. PMID: 29575830.
      View in: PubMed
    5. Bebarta VS, Garrett N, Brenner M, Mahon SB, Maddry JK, Boudreau S, Castaneda M, Boss GR. Efficacy of Intravenous Cobinamide Versus Hydroxocobalamin or Saline for Treatment of Severe Hydrogen Sulfide Toxicity in a Swine (Sus scrofa) Model. Acad Emerg Med. 2017 Sep; 24(9):1088-1098. PMID: 28472554.
      View in: PubMed
    6. Brenner M, Azer SM, Oh KJ, Han CH, Lee J, Mahon SB, Du X, Mukai D, Burney T, Saidian M, Chan A, Straker DI, Bebarta VS, Boss GR. Oral Glycine and Sodium Thiosulfate for Lethal Cyanide Ingestion. J Clin Toxicol. 2017 Jun; 7(3). PMID: 28868209.
      View in: PubMed
    7. Nath AK, Shi X, Harrison DL, Morningstar JE, Mahon S, Chan A, Sips P, Lee J, MacRae CA, Boss GR, Brenner M, Gerszten RE, Peterson RT. Cisplatin Analogs Confer Protection against Cyanide Poisoning. Cell Chem Biol. 2017 May 18; 24(5):565-575.e4. PMID: 28416275.
      View in: PubMed
    8. Bebarta VS, Brittain M, Chan A, Garrett N, Yoon D, Burney T, Mukai D, Babin M, Pilz RB, Mahon SB, Brenner M, Boss GR. Sodium Nitrite and Sodium Thiosulfate Are Effective Against Acute Cyanide Poisoning When Administered by Intramuscular Injection. Ann Emerg Med. 2017 Jun; 69(6):718-725.e4. PMID: 28041825.
      View in: PubMed
    9. Lee J, Mahon SB, Mukai D, Burney T, Katebian BS, Chan A, Bebarta VS, Yoon D, Boss GR, Brenner M. The Vitamin B12 Analog Cobinamide Is an Effective Antidote for Oral Cyanide Poisoning. J Med Toxicol. 2016 Dec; 12(4):370-379. PMID: 27631586.
      View in: PubMed
    10. MacRae CA, Boss G, Brenner M, Gerszten RE, Mahon S, Peterson RT. A countermeasure development pipeline. Ann N Y Acad Sci. 2016 08; 1378(1):58-67. PMID: 27737495.
      View in: PubMed
    11. Jiang J, Chan A, Ali S, Saha A, Haushalter KJ, Lam WL, Glasheen M, Parker J, Brenner M, Mahon SB, Patel HH, Ambasudhan R, Lipton SA, Pilz RB, Boss GR. Hydrogen Sulfide--Mechanisms of Toxicity and Development of an Antidote. Sci Rep. 2016 Feb 15; 6:20831. PMID: 26877209; PMCID: PMC4753484.
    12. Heidari AE, Moghaddam S, Truong KK, Chou L, Genberg C, Brenner M, Chena Z. Errata: Visualizing biofilm formation in endotracheal tubes using endoscopic three-dimensional optical coherence tomography. J Biomed Opt. 2016 Feb; 21(2):29802. PMID: 26903148.
      View in: PubMed
    13. Chan A, Jiang J, Fridman A, Guo LT, Shelton GD, Liu MT, Green C, Haushalter KJ, Patel HH, Lee J, Yoon D, Burney T, Mukai D, Mahon SB, Brenner M, Pilz RB, Boss GR. Nitrocobinamide, a new cyanide antidote that can be administered by intramuscular injection. J Med Chem. 2015 Feb 26; 58(4):1750-9. PMID: 25650735; PMCID: PMC4494098.
    14. Heidari AE, Moghaddam S, Truong KK, Troung KK, Chou L, Genberg C, Brenner M, Chen Z. Visualizing biofilm formation in endotracheal tubes using endoscopic three-dimensional optical coherence tomography. J Biomed Opt. 2015; 20(12):126010. PMID: 26720877; PMCID: PMC4686586 [Available on 12/22/16].
    15. Lee J, Kim JG, Mahon SB, Mukai D, Yoon D, Boss GR, Patterson SE, Rockwood G, Isom G, Brenner M. Noninvasive optical cytochrome c oxidase redox state measurements using diffuse optical spectroscopy. J Biomed Opt. 2014 May; 19(5):055001. PMID: 24788369; PMCID: PMC4006145.
    16. Bhandari RK, Oda RP, Petrikovics I, Thompson DE, Brenner M, Mahon SB, Bebarta VS, Rockwood GA, Logue BA. Cyanide toxicokinetics: the behavior of cyanide, thiocyanate and 2-amino-2-thiazoline-4-carboxylic acid in multiple animal models. J Anal Toxicol. 2014 May; 38(4):218-25. PMID: 24711295; PMCID: PMC3977587.
    17. Chou L, Batchinsky A, Belenkiy S, Jing J, Ramalingam T, Brenner M, Chen Z. In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography. J Biomed Opt. 2014 Mar; 19(3):36018. PMID: 24664245; PMCID: PMC3963560.
    18. Li X, Li J, Jing J, Ma T, Liang S, Zhang J, Mohar D, Raney A, Mahon S, Brenner M, Patel P, Shung KK, Zhou Q, Chen Z. Integrated IVUS-OCT Imaging for Atherosclerotic Plaque Characterization. IEEE J Sel Top Quantum Electron. 2014 Mar; 20(2):7100108. PMID: 24771992.
      View in: PubMed
    19. Jackson R, Oda RP, Bhandari RK, Mahon SB, Brenner M, Rockwood GA, Logue BA. Development of a fluorescence-based sensor for rapid diagnosis of cyanide exposure. Anal Chem. 2014 Feb 04; 86(3):1845-52. PMID: 24383576; PMCID: PMC3983020.
    20. Li J, Li X, Mohar D, Raney A, Jing J, Zhang J, Johnston A, Liang S, Ma T, Shung KK, Mahon S, Brenner M, Narula J, Zhou Q, Patel PM, Chen Z. Integrated IVUS-OCT for real-time imaging of coronary atherosclerosis. JACC Cardiovasc Imaging. 2014 Jan; 7(1):101-3. PMID: 24433713.
      View in: PubMed
    21. Tian Y, Dasgupta PK, Mahon SB, Ma J, Brenner M, Wang JH, Boss GR. A disposable blood cyanide sensor. Anal Chim Acta. 2013 Mar 20; 768:129-35. PMID: 23473259; PMCID: PMC3596829.
    22. Nath AK, Roberts LD, Liu Y, Mahon SB, Kim S, Ryu JH, Werdich A, Januzzi JL, Boss GR, Rockwood GA, MacRae CA, Brenner M, Gerszten RE, Peterson RT. Chemical and metabolomic screens identify novel biomarkers and antidotes for cyanide exposure. FASEB J. 2013 May; 27(5):1928-38. PMID: 23345455; PMCID: PMC3633825.
    23. Kim JG, Lee J, Mahon SB, Mukai D, Patterson SE, Boss GR, Tromberg BJ, Brenner M. Noninvasive monitoring of treatment response in a rabbit cyanide toxicity model reveals differences in brain and muscle metabolism. J Biomed Opt. 2012 Oct; 17(10):105005. PMID: 23223999; PMCID: PMC3603151.
    24. Suter MJ, Lam S, Brenner M. Optical techniques in pulmonary medicine. SPIE photonics West. Expert Rev Respir Med. 2012 Apr; 6(2):143-5. PMID: 22455486.
      View in: PubMed
    25. Li J, Li X, Jing J, Mohar D, Raney A, Mahon S, Brenner M, Zhou Q, Patel P, Shung KK, Chen Z. Integrated intravascular optical coherence tomography (OCT) - ultrasound (US) catheter for characterization of atherosclerotic plaques in vivo. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:3175-8. PMID: 23366600.
      View in: PubMed
    26. Robertson C, Lee SW, Ahn YC, Mahon S, Chen Z, Brenner M, George SC. Investigating in vivo airway wall mechanics during tidal breathing with optical coherence tomography. J Biomed Opt. 2011 Oct; 16(10):106011. PMID: 22029358; PMCID: PMC3210193.
    27. Chan A, Crankshaw DL, Monteil A, Patterson SE, Nagasawa HT, Briggs JE, Kozocas JA, Mahon SB, Brenner M, Pilz RB, Bigby TD, Boss GR. The combination of cobinamide and sulfanegen is highly effective in mouse models of cyanide poisoning. Clin Toxicol (Phila). 2011 Jun; 49(5):366-73. PMID: 21740135; PMCID: PMC3882312.
    28. Yin J, Li X, Jing J, Li J, Mukai D, Mahon S, Edris A, Hoang K, Shung KK, Brenner M, Narula J, Zhou Q, Chen Z. Novel combined miniature optical coherence tomography ultrasound probe for in vivo intravascular imaging. J Biomed Opt. 2011 Jun; 16(6):060505. PMID: 21721799; PMCID: PMC3124531.
    29. Ma J, Ohira S, Mishra SK, Puanngam M, Dasgupta PK, Mahon SB, Brenner M, Blackledge W, Boss GR. Rapid point of care analyzer for the measurement of cyanide in blood. Anal Chem. 2011 Jun 01; 83(11):4319-24. PMID: 21553921; PMCID: PMC3105183.
    30. Lee SW, Heidary AE, Yoon D, Mukai D, Ramalingam T, Mahon S, Yin J, Jing J, Liu G, Chen Z, Brenner M. Quantification of airway thickness changes in smoke-inhalation injury using in-vivo 3-D endoscopic frequency-domain optical coherence tomography. Biomed Opt Express. 2011 Jan 05; 2(2):243-54. PMID: 21339870; PMCID: PMC3038440.
    31. Brenner M, Kim JG, Lee J, Mahon SB, Lemor D, Ahdout R, Boss GR, Blackledge W, Jann L, Nagasawa HT, Patterson SE. Sulfanegen sodium treatment in a rabbit model of sub-lethal cyanide toxicity. Toxicol Appl Pharmacol. 2010 Nov 01; 248(3):269-76. PMID: 20705081; PMCID: PMC3382974.
    32. Blackledge WC, Blackledge CW, Griesel A, Mahon SB, Brenner M, Pilz RB, Boss GR. New facile method to measure cyanide in blood. Anal Chem. 2010 May 15; 82(10):4216-21. PMID: 20420400; PMCID: PMC2889625.
    33. Brenner M, Kim JG, Mahon SB, Lee J, Kreuter KA, Blackledge W, Mukai D, Patterson S, Mohammad O, Sharma VS, Boss GR. Intramuscular cobinamide sulfite in a rabbit model of sublethal cyanide toxicity. Ann Emerg Med. 2010 Apr; 55(4):352-63. PMID: 20045579; PMCID: PMC2963429.
    34. Raub CB, Mahon S, Narula N, Tromberg BJ, Brenner M, George SC. Linking optics and mechanics in an in vivo model of airway fibrosis and epithelial injury. J Biomed Opt. 2010 Jan-Feb; 15(1):015004. PMID: 20210444; PMCID: PMC2844131.
    35. Brenner M, Mahon SB, Lee J, Kim J, Mukai D, Goodman S, Kreuter KA, Ahdout R, Mohammad O, Sharma VS, Blackledge W, Boss GR. Comparison of cobinamide to hydroxocobalamin in reversing cyanide physiologic effects in rabbits using diffuse optical spectroscopy monitoring. J Biomed Opt. 2010 Jan-Feb; 15(1):017001. PMID: 20210475; PMCID: PMC2816993.
    36. Xie T, Liu G, Kreuter K, Mahon S, Colt H, Mukai D, Peavy GM, Chen Z, Brenner M. In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance. J Biomed Opt. 2009 Nov-Dec; 14(6):064045. PMID: 20059283; PMCID: PMC2809499.
    37. Yin J, Liu G, Zhang J, Yu L, Mahon S, Mukai D, Brenner M, Chen Z. In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography. J Biomed Opt. 2009 Nov-Dec; 14(6):060503. PMID: 20059234; PMCID: PMC2801726.
    38. Kreuter KA, Mahon SB, Mukai DS, Su J, Jung WG, Narula N, Guo S, Wakida N, Raub C, Berns MW, George SC, Chen Z, Brenner M. Detection and monitoring of early airway injury effects of half-mustard (2-chloroethylethylsulfide) exposure using high-resolution optical coherence tomography. J Biomed Opt. 2009 Jul-Aug; 14(4):044037. PMID: 19725748; PMCID: PMC2792700.
    39. Lee J, Kim JG, Mahon S, Tromberg BJ, Mukai D, Kreuter K, Saltzman D, Patino R, Goldberg R, Brenner M. Broadband diffuse optical spectroscopy assessment of hemorrhage- and hemoglobin-based blood substitute resuscitation. J Biomed Opt. 2009 Jul-Aug; 14(4):044027. PMID: 19725738; PMCID: PMC2868523.
    40. Lee J, Keuter KA, Kim J, Tran A, Uppal A, Mukai D, Mahon SB, Cancio LC, Batchinsky A, Tromberg BJ, Brenner M. Noninvasive in vivo monitoring of cyanide toxicity and treatment using diffuse optical spectroscopy in a rabbit model. Mil Med. 2009 Jun; 174(6):615-21. PMID: 19585775; PMCID: PMC4010306.
    41. Hoang KC, Edris A, Su J, Mukai DS, Mahon S, Petrov AD, Kern M, Ashan C, Chen Z, Tromberg BJ, Narula J, Brenner M. Use of an oxygen-carrying blood substitute to improve intravascular optical coherence tomography imaging. J Biomed Opt. 2009 May-Jun; 14(3):034028. PMID: 19566321; PMCID: PMC2792695.
    42. Malavia NK, Raub CB, Mahon SB, Brenner M, Panettieri RA, George SC. Airway epithelium stimulates smooth muscle proliferation. Am J Respir Cell Mol Biol. 2009 Sep; 41(3):297-304. PMID: 19151317; PMCID: PMC2742749.
    43. Lee J, Kim JG, Mahon S, Tromberg BJ, Ryan KL, Convertino VA, Rickards CA, Osann K, Brenner M. Tissue hemoglobin monitoring of progressive central hypovolemia in humans using broadband diffuse optical spectroscopy. J Biomed Opt. 2008 Nov-Dec; 13(6):064027. PMID: 19123673; PMCID: PMC4079508.
    44. Kreuter KA, El-Abbadi N, Shbeeb A, Tseng L, Mahon SB, Narula N, Burney T, Colt H, Brenner M. Development of a rabbit pleural cancer model by using VX2 tumors. Comp Med. 2008 Jun; 58(3):287-93. PMID: 18589872; PMCID: PMC2704119.
    45. Brenner M, Kreuter K, Ju J, Mahon S, Tseng L, Mukai D, Burney T, Guo S, Su J, Tran A, Batchinsky A, Cancio LC, Narula N, Chen Z. In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model. J Biomed Opt. 2008 May-Jun; 13(3):034001. PMID: 18601546; PMCID: PMC2778034.
    46. Su J, Zhang J, Yu L, G Colt H, Brenner M, Chen Z. Real-time swept source optical coherence tomography imaging of the human airway using a microelectromechanical system endoscope and digital signal processor. J Biomed Opt. 2008 May-Jun; 13(3):030506. PMID: 18601523; PMCID: PMC2777978.
    47. Brenner M, Kreuter K, Mukai D, Burney T, Guo S, Su J, Mahon S, Tran A, Tseng L, Ju J, Chen Z. Detection of acute smoke-induced airway injury in a New Zealand white rabbit model using optical coherence tomography. J Biomed Opt. 2007 Sep-Oct; 12(5):051701. PMID: 17994874.
      View in: PubMed
    48. Lee J, Armstrong J, Kreuter K, Tromberg BJ, Brenner M. Non-invasive in vivo diffuse optical spectroscopy monitoring of cyanide poisoning in a rabbit model. Physiol Meas. 2007 Sep; 28(9):1057-66. PMID: 17827653.
      View in: PubMed
    49. Lee J, Mukai D, Kreuter K, Mahon S, Tromberg B, Brenner M. Potential interference by hydroxocobalamin on cooximetry hemoglobin measurements during cyanide and smoke inhalation treatments. Ann Emerg Med. 2007 Jun; 49(6):802-5. PMID: 17210205.
      View in: PubMed
    50. Mahmood U, Hanna NM, Han S, Jung WG, Chen Z, Jordan B, Yershov A, Walton R, Brenner M. Evaluation of rabbit tracheal inflammation using optical coherence tomography. Chest. 2006 Sep; 130(3):863-8. PMID: 16963687.
      View in: PubMed
    51. Hanna NM, Waite W, Taylor K, Jung WG, Mukai D, Matheny E, Kreuter K, Wilder-Smith P, Brenner M, Chen Z. Feasibility of three-dimensional optical coherence tomography and optical Doppler tomography of malignancy in hamster cheek pouches. Photomed Laser Surg. 2006 Jun; 24(3):402-9. PMID: 16875451.
      View in: PubMed
    52. Xie T, Guo S, Chen Z, Mukai D, Brenner M. GRIN lens rod based probe for endoscopic spectral domain optical coherence tomography with fast dynamic focus tracking. Opt Express. 2006 Apr 17; 14(8):3238-46. PMID: 19516465.
      View in: PubMed
    53. Lee J, El-Abaddi N, Duke A, Cerussi AE, Brenner M, Tromberg BJ. Noninvasive in vivo monitoring of methemoglobin formation and reduction with broadband diffuse optical spectroscopy. J Appl Physiol (1985). 2006 Feb; 100(2):615-22. PMID: 16223982.
      View in: PubMed
    54. Han S, El-Abbadi NH, Hanna N, Mahmood U, Mina-Araghi R, Jung WG, Chen Z, Colt H, Brenner M. Evaluation of tracheal imaging by optical coherence tomography. Respiration. 2005 Sep-Oct; 72(5):537-41. PMID: 16210894.
      View in: PubMed
    55. Xie T, Mukai D, Guo S, Brenner M, Chen Z. Fiber-optic-bundle-based optical coherence tomography. Opt Lett. 2005 Jul 15; 30(14):1803-5. PMID: 16092351.
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    56. Matheny ES, Hanna NM, Jung WG, Chen Z, Wilder-Smith P, Mina-Araghi R, Brenner M. Optical coherence tomography of malignancy in hamster cheek pouches. J Biomed Opt. 2004 Sep-Oct; 9(5):978-81. PMID: 15447019.
      View in: PubMed
    57. Brenner M, Hanna NM, Mina-Araghi R, Gelb AF, McKenna RJ, Colt H. Innovative approaches to lung volume reduction for emphysema. Chest. 2004 Jul; 126(1):238-48. PMID: 15249467.
      View in: PubMed
    58. Tran PH, Mukai DS, Brenner M, Chen Z. In vivo endoscopic optical coherence tomography by use of a rotational microelectromechanical system probe. Opt Lett. 2004 Jun 01; 29(11):1236-8. PMID: 15209258.
      View in: PubMed
    59. Wilder-Smith P, Jung WG, Brenner M, Osann K, Beydoun H, Messadi D, Chen Z. In vivo optical coherence tomography for the diagnosis of oral malignancy. Lasers Surg Med. 2004; 35(4):269-75. PMID: 15493024.
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    60. Jung W, Zhang J, Mina-Araghi R, Hanna N, Brenner M, Nelson JS, Chen Z. Feasibility study of normal and septic tracheal imaging using optical coherence tomography. Lasers Surg Med. 2004; 35(2):121-7. PMID: 15334615.
      View in: PubMed
    61. Brenner M, Jones B, Daneschvar HL, Triff S. New National Emphysema Treatment Trial paradigm of Health Care Financing Administration-sponsored clinical research trials: advances and dilemmas. J Investig Med. 2002 Mar; 50(2):95-100. PMID: 11928948.
      View in: PubMed
    62. Brenner M, Gonzalez X, Jones B, Ha R, Osann K, McKenna R, Milliken J. Effects of a novel implantable elastomer device for lung volume reduction surgery in a rabbit model of elastase-induced emphysema. Chest. 2002 Jan; 121(1):201-9. PMID: 11796452.
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    63. Pham TH, Hornung R, Ha HP, Burney T, Serna D, Powell L, Brenner M, Tromberg BJ. Noninvasive monitoring of hemodynamic stress using quantitative near-infrared frequency-domain photon migration spectroscopy. J Biomed Opt. 2002 Jan; 7(1):34-44. PMID: 11818010.
      View in: PubMed
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