Ali Ezzati

Title(s)Associate Clinical Professor, Neurology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-6808
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    Predictive analytics for cognitive decline and Alzheimer?s disease
    NIH K23AG063993Aug 1, 2020 - Apr 30, 2025
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Genetic and Clinical Correlates of AI-Based Brain Aging Patterns in Cognitively Unimpaired Individuals. JAMA Psychiatry. 2024 Feb 14. Skampardoni I, Nasrallah IM, Abdulkadir A, Wen J, Melhem R, Mamourian E, Erus G, Doshi J, Singh A, Yang Z, Cui Y, Hwang G, Ren Z, Pomponio R, Srinivasan D, Govindarajan ST, Parmpi P, Wittfeld K, Grabe HJ, Bülow R, Frenzel S, Tosun D, Bilgel M, An Y, Marcus DS, LaMontagne P, Heckbert SR, Austin TR, Launer LJ, Sotiras A, Espeland MA, Masters CL, Maruff P, Fripp J, Johnson SC, Morris JC, Albert MS, Bryan RN, Yaffe K, Völzke H, Ferrucci L, Benzinger TLS, Ezzati A, Shinohara RT, Fan Y, Resnick SM, Habes M, Wolk D, Shou H, Nikita K, Davatzikos C. PMID: 38353984; PMCID: PMC10867779.
      View in: PubMed   Mentions:    Fields:    
    2. Plasma Biomarkers as Predictors of Progression to Dementia in Individuals with Mild Cognitive Impairment. J Alzheimers Dis. 2024; 98(1):231-246. Nallapu BT, Petersen KK, Lipton RB, Davatzikos C, Ezzati A, Alzheimer’s Disease Neuroimaging Initiative. PMID: 38393899.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Association of Stages of Objective Memory Impairment With Incident Symptomatic Cognitive Impairment in Cognitively Normal Individuals. Neurology. 2023 05 30; 100(22):e2279-e2289. Grober E, Petersen KK, Lipton RB, Hassenstab J, Morris JC, Gordon BA, Ezzati A. PMID: 37076305; PMCID: PMC10259282.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Tracking cognition with the T-MoCA in a racially/ethnically diverse older adult cohort. Alzheimers Dement (Amst). 2023 Jan-Mar; 15(1):e12410. Wang C, Nester CO, Chang K, Rabin LA, Ezzati A, Lipton RB, Katz MJ. PMID: 36950700; PMCID: PMC10026378.
      View in: PubMed   Mentions: 1  
    5. Predictors of treatment-response to caffeine combination products, acetaminophen, acetylsalicylic acid (aspirin), and nonsteroidal anti-inflammatory drugs in acute treatment of episodic migraine. Headache. 2023 03; 63(3):342-352. Ezzati A, Fanning KM, Reed ML, Lipton RB. PMID: 36748728.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Association of Alcohol Consumption with Cognition in Older Population: The A4 Study. J Alzheimers Dis. 2023; 93(4):1381-1393. Nallapu BT, Petersen KK, Lipton RB, Grober E, Sperling RA, Ezzati A. PMID: 37182868; PMCID: PMC10392870.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Predictors of treatment-response to acute prescription medications in migraine: Results from the American Migraine Prevalence and Prevention (AMPP) Study. Clin Neurol Neurosurg. 2022 12; 223:107511. Ezzati A, Buse DC, Fanning KM, Reed ML, Martin VT, Lipton RB. PMID: 36395587.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Predictive models for determining treatment response to nonprescription acute medications in migraine: Results from the American Migraine Prevalence and Prevention Study. Headache. 2022 06; 62(6):755-765. Ezzati A, Fanning KM, Buse DC, Pavlovic JM, Armand CE, Reed ML, Martin VT, Lipton RB. PMID: 35546653.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Predicting Amyloid Positivity in Cognitively Unimpaired Older Adults: A Machine Learning Approach Using A4 Data. Neurology. 2022 06 14; 98(24):e2425-e2435. Petersen KK, Lipton RB, Grober E, Davatzikos C, Sperling RA, Ezzati A. PMID: 35470142; PMCID: PMC9231843.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    10. Application of predictive models in boosting power of Alzheimer's disease clinical trials: A post hoc analysis of phase 3 solanezumab trials. Alzheimers Dement (N Y). 2022; 8(1):e12223. Ezzati A, Davatzikos C, Wolk DA, Hall CB, Habeck C, Lipton RB. PMID: 35310531; PMCID: PMC8919041.
      View in: PubMed   Mentions: 2  
    11. Associations of Stages of Objective Memory Impairment With Amyloid PET and Structural MRI: The A4 Study. Neurology. 2022 03 29; 98(13):e1327-e1336. Grober E, Lipton RB, Sperling RA, Papp KV, Johnson KA, Rentz DM, Veroff AE, Aisen PS, Ezzati A. PMID: 35197359; PMCID: PMC8967421.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    12. Impact of sex and APOE ε4 on the association of cognition and hippocampal volume in clinically normal, amyloid positive adults. Alzheimers Dement (Amst). 2022; 14(1):e12271. Petersen KK, Grober E, Lipton RB, Sperling RA, Buckley RF, Aisen PS, Ezzati A. PMID: 35155730; PMCID: PMC8828988.
      View in: PubMed   Mentions: 4  
    13. Anterior cervical corpectomy and fusion with stand-alone cages in patients with multilevel degenerative cervical spine disease is safe. BMC Musculoskelet Disord. 2022 Jan 03; 23(1):20. Tohamy MH, Osterhoff G, Abdelgawaad AS, Ezzati A, Heyde CE. PMID: 34980062; PMCID: PMC8725343.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    14. Association of Depressive Symptoms and Cognition in Older Adults Without Dementia Across Different Biomarker Profiles. J Alzheimers Dis. 2022; 88(4):1385-1395. Rubin-Norowitz M, Lipton RB, Petersen K, Ezzati A, Alzheimer’s Disease Neuroimaging Initiative. PMID: 35786653; PMCID: PMC9723980.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Neuroimaging correlates of Stages of Objective Memory Impairment (SOMI) system. Alzheimers Dement (Amst). 2021; 13(1):e12224. Grober E, Papp KV, Rentz DM, Sperling RA, Johnson KA, Amariglio RE, Schultz A, Lipton RB, Ezzati A. PMID: 35005192; PMCID: PMC8719429.
      View in: PubMed   Mentions: 4  
    16. Predictive value of ATN biomarker profiles in estimating disease progression in Alzheimer's disease dementia. Alzheimers Dement. 2021 11; 17(11):1855-1867. Ezzati A, Abdulkadir A, Jack CR, Thompson PM, Harvey DJ, Truelove-Hill M, Sreepada LP, Davatzikos C, Alzheimer's Disease Neuroimaging Initiative, Lipton RB. PMID: 34870371; PMCID: PMC8842842.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    17. Leveraging machine learning predictive biomarkers to augment the statistical power of clinical trials with baseline magnetic resonance imaging. Brain Commun. 2021; 3(4):fcab264. Lou C, Habes M, Illenberger NA, Ezzati A, Lipton RB, Shaw PA, Stephens-Shields AJ, Akbari H, Doshi J, Davatzikos C, Shinohara RT. PMID: 34806001; PMCID: PMC8600962.
      View in: PubMed   Mentions: 5  
    18. Comparing Performance of Different Predictive Models in Estimating Disease Progression in Alzheimer Disease. Alzheimer Dis Assoc Disord. 2022 Apr-Jun 01; 36(2):176-179. Ezzati A, Zammit AR, Lipton RB. PMID: 34393191; PMCID: PMC8847534.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Radiofrequency ablation and balloon kyphoplasty for palliation of painful spinal metastases. Eur Spine J. 2021 10; 30(10):2874-2880. Shawky Abdelgawaad A, Ezzati A, Krajnovic B, Seyed-Emadaldin S, Abdelrahman H. PMID: 33961090.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    20. White matter hyperintensities and cognition across different Alzheimer's biomarker profiles. J Am Geriatr Soc. 2021 07; 69(7):1906-1915. Lam S, Lipton RB, Harvey DJ, Zammit AR, Ezzati A, Alzheimer's Disease Neuroimaging Initiative. PMID: 33891712; PMCID: PMC8456365.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    21. Trans-Tubular Translaminar Microscopic-Assisted Nucleotomy for Lumbar Disc Herniations in the Hidden Zone. Global Spine J. 2022 Sep; 12(7):1420-1427. Abdelrahman H, Seyed-Emadaldin S, Krajnovic B, Ezzati A, Abdelgawaad AS. PMID: 33530710; PMCID: PMC9393970.
      View in: PubMed   Mentions:
    22. Detecting biological heterogeneity patterns in ADNI amnestic mild cognitive impairment based on volumetric MRI. Brain Imaging Behav. 2020 Oct; 14(5):1792-1804. Ezzati A, Zammit AR, Habeck C, Hall CB, Lipton RB, Alzheimer’s Disease Neuroimaging Initiative. PMID: 31104279; PMCID: PMC7203761.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    23. Machine Learning Predictive Models Can Improve Efficacy of Clinical Trials for Alzheimer's Disease. J Alzheimers Dis. 2020; 74(1):55-63. Ezzati A, Lipton RB, Alzheimer’s Disease Neuroimaging Initiative. PMID: 31985462; PMCID: PMC7201366.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    24. Effect of Mentally Challenging Occupations on Incident Dementia Differs Between African Americans and Non-Hispanic Whites. J Alzheimers Dis. 2020; 75(4):1405-1416. Hyun J, Hall CB, Sliwinski MJ, Katz MJ, Wang C, Ezzati A, Lipton RB. PMID: 32417772; PMCID: PMC7874241.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    25. Predicting Amyloid-β Levels in Amnestic Mild Cognitive Impairment Using Machine Learning Techniques. J Alzheimers Dis. 2020; 73(3):1211-1219. Ezzati A, Harvey DJ, Habeck C, Golzar A, Qureshi IA, Zammit AR, Hyun J, Truelove-Hill M, Hall CB, Davatzikos C, Lipton RB, Alzheimer’s Disease Neuroimaging Initiative. PMID: 31884486; PMCID: PMC7376527.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    26. Neuropsychological latent classes at enrollment and postmortem neuropathology. Alzheimers Dement. 2019 09; 15(9):1195-1207. Zammit AR, Hall CB, Bennett DA, Ezzati A, Katz MJ, Muniz-Terrera G, Lipton RB. PMID: 31420203; PMCID: PMC6756968.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    27. Health-related Quality of Life, Cognitive Performance, and Incident Dementia in a Community-based Elderly Cohort. Alzheimer Dis Assoc Disord. 2019 Jul-Sep; 33(3):240-245. Ezzati A, Zammit AR, Katz MJ, Derby CA, Zimmerman ME, Lipton RB. PMID: 31135451; PMCID: PMC6710122.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    28. The relationship between hippocampal volume, chronic pain, and depressive symptoms in older adults. Psychiatry Res Neuroimaging. 2019 07 30; 289:10-12. Ezzati A, Zammit AR, Lipton ML, Lipton RB. PMID: 31112826; PMCID: PMC6645699.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. Depressive Symptoms Predict Incident Dementia in a Community Sample of Older Adults: Results From the Einstein Aging Study. J Geriatr Psychiatry Neurol. 2019 Jan 10; 891988718824036. Ezzati A, Katz MJ, Derby CA, Zimmerman ME, Lipton RB. PMID: 30630387; PMCID: PMC7201340.
      View in: PubMed   Mentions: 13     Fields:    
    30. Subtypes Based on Neuropsychological Performance Predict Incident Dementia: Findings from the Rush Memory and Aging Project. J Alzheimers Dis. 2019; 67(1):125-135. Zammit AR, Muniz-Terrera G, Katz MJ, Hall CB, Ezzati A, Bennett DA, Lipton RB. PMID: 30507576; PMCID: PMC6335582.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    31. Optimizing Machine Learning Methods to Improve Predictive Models of Alzheimer's Disease. J Alzheimers Dis. 2019; 71(3):1027-1036. Ezzati A, Zammit AR, Harvey DJ, Habeck C, Hall CB, Lipton RB, Alzheimer’s Disease Neuroimaging Initiative. PMID: 31476152; PMCID: PMC6993918.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    32. The Temporal Relationship between Pain Intensity and Pain Interference and Incident Dementia. Curr Alzheimer Res. 2019; 16(2):109-115. Ezzati A, Wang C, Katz MJ, Derby CA, Zammit AR, Zimmerman ME, Pavlovic JM, Sliwinski MJ, Lipton RB. PMID: 30543173; PMCID: PMC6484854.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    33. Class-Specific Incidence of All-Cause Dementia and Alzheimer's Disease: A Latent Class Approach. J Alzheimers Dis. 2018; 66(1):347-357. Zammit AR, Hall CB, Katz MJ, Muniz-Terrera G, Ezzati A, Bennett DA, Lipton RB. PMID: 30282367; PMCID: PMC6329008.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    34. Odontoid-sparing transnasal approach for drainage of craniocervical epidural abscess; a novel technique and review of the literature. Spine J. 2018 03; 18(3):540-546. Shawky Abdelgawaad A, Kellner G, Elnady B, Ezzati A. PMID: 29253634.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. Kyphoplasty for osteoporotic vertebral fractures with posterior wall injury. Spine J. 2018 07; 18(7):1143-1148. Abdelgawaad AS, Ezzati A, Govindasamy R, Krajnovic B, Elnady B, Said GZ. PMID: 29154997.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    36. Transcranial Doppler and Lower Extremity Function in Older Adults: Einstein Aging Study. J Am Geriatr Soc. 2017 Dec; 65(12):2659-2664. Ezzati A, Rundek T, Verghese J, Derby CA. PMID: 29130477; PMCID: PMC5729099.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    37. The association of visual memory with hippocampal volume. PLoS One. 2017; 12(11):e0187851. Zammit AR, Ezzati A, Katz MJ, Zimmerman ME, Lipton ML, Sliwinski MJ, Lipton RB. PMID: 29117260; PMCID: PMC5678713.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    38. Extraforaminal microscopic assisted percutaneous nucleotomy for foraminal and extraforaminal lumbar disc herniations. Spine J. 2018 04; 18(4):620-625. Shawky Abdelgawaad A, Babic D, Siam AE, Ezzati A. PMID: 28882526.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Longus colli tendinitis. A review of literature and case series. SICOT J. 2017; 3:48. Shawky A, Elnady B, El-Morshidy E, Gad W, Ezzati A. PMID: 28664844; PMCID: PMC5492790.
      View in: PubMed   Mentions: 12  
    40. Inter-Rater Reliability of Preprocessing EEG Data: Impact of Subjective Artifact Removal on Associative Memory Task ERP Results. Front Neurosci. 2017; 11:322. Shirk SD, McLaren DG, Bloomfield JS, Powers A, Duffy A, Mitchell MB, Ezzati A, Ally BA, Atri A. PMID: 28670264; PMCID: PMC5472725.
      View in: PubMed   Mentions: 2  
    41. Association Between Vascular Pathology and Rate of Cognitive Decline Independent of Alzheimer's Disease Pathology. J Am Geriatr Soc. 2017 Aug; 65(8):1836-1841. Ezzati A, Wang C, Lipton RB, Altschul D, Katz MJ, Dickson DW, Derby CA. PMID: 28407205; PMCID: PMC5555777.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    42. Roles of hippocampal subfields in verbal and visual episodic memory. Behav Brain Res. 2017 01 15; 317:157-162. Zammit AR, Ezzati A, Zimmerman ME, Lipton RB, Lipton ML, Katz MJ. PMID: 27646772; PMCID: PMC6343125.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    43. Hippocampal volume and cingulum bundle fractional anisotropy are independently associated with verbal memory in older adults. Brain Imaging Behav. 2016 09; 10(3):652-9. Ezzati A, Katz MJ, Lipton ML, Zimmerman ME, Lipton RB. PMID: 26424564; PMCID: PMC4816657.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    44. Differential association of left and right hippocampal volumes with verbal episodic and spatial memory in older adults. Neuropsychologia. 2016 Dec; 93(Pt B):380-385. Ezzati A, Katz MJ, Zammit AR, Lipton ML, Zimmerman ME, Sliwinski MJ, Lipton RB. PMID: 27542320; PMCID: PMC5154822.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    45. Pain Intensity and Pain Interference in Older Adults: Role of Gender, Obesity and High-Sensitivity C-Reactive Protein. Gerontology. 2017; 63(1):3-12. Eslami V, Katz MJ, White RS, Sundermann E, Jiang JM, Ezzati A, Lipton RB. PMID: 27486843; PMCID: PMC5154794.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    46. Recognition of faces and names: multimodal physiological correlates of memory and executive function. Brain Imaging Behav. 2016 06; 10(2):408-23. Mitchell MB, Shirk SD, McLaren DG, Dodd JS, Ezzati A, Ally BA, Atri A. PMID: 26116280.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    47. Perceived Stress Is Differentially Related to Hippocampal Subfield Volumes among Older Adults. PLoS One. 2016; 11(5):e0154530. Zimmerman ME, Ezzati A, Katz MJ, Lipton ML, Brickman AM, Sliwinski MJ, Lipton RB. PMID: 27144832; PMCID: PMC4856349.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    48. Influence of Perceived Stress on Incident Amnestic Mild Cognitive Impairment: Results From the Einstein Aging Study. Alzheimer Dis Assoc Disord. 2016 Apr-Jun; 30(2):93-8. Katz MJ, Derby CA, Wang C, Sliwinski MJ, Ezzati A, Zimmerman ME, Zwerling JL, Lipton RB. PMID: 26655068; PMCID: PMC4877262.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    49. The association of brain structure with gait velocity in older adults: a quantitative volumetric analysis of brain MRI. Neuroradiology. 2015 Aug; 57(8):851-61. Ezzati A, Katz MJ, Lipton ML, Lipton RB, Verghese J. PMID: 25921321; PMCID: PMC4553137.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    50. Hippocampal subfields differentially correlate with chronic pain in older adults. Brain Res. 2014 Jul 21; 1573:54-62. Ezzati A, Zimmerman ME, Katz MJ, Sundermann EE, Smith JL, Lipton ML, Lipton RB. PMID: 24878607; PMCID: PMC4111097.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    51. Validation of the Perceived Stress Scale in a community sample of older adults. Int J Geriatr Psychiatry. 2014 Jun; 29(6):645-52. Ezzati A, Jiang J, Katz MJ, Sliwinski MJ, Zimmerman ME, Lipton RB. PMID: 24302253; PMCID: PMC4013212.
      View in: PubMed   Mentions: 84     Fields:    Translation:Humans
    52. Hippocampal correlates of depression in healthy elderly adults. Hippocampus. 2013 Dec; 23(12):1137-42. Ezzati A, Zimmerman ME, Katz MJ, Lipton RB. PMID: 23939871; PMCID: PMC4018740.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    53. Infection after vertebroplasty or kyphoplasty. A series of nine cases and review of literature. Spine J. 2013 Dec; 13(12):1809-17. Abdelrahman H, Siam AE, Shawky A, Ezzati A, Boehm H. PMID: 23880354.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    54. Is inclusion of the occiput necessary in fusion for C1-2 instability in rheumatoid arthritis? J Neurosurg Spine. 2013 Jan; 18(1):50-6. Werle S, Ezzati A, ElSaghir H, Boehm H. PMID: 23157277.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    55. Four-level anterior cervical discectomies and cage-augmented fusion with and without fixation. Eur Spine J. 2012 Dec; 21(12):2512-9. Shousha M, Ezzati A, Boehm H. PMID: 22814566; PMCID: PMC3508214.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    56. Low-level laser therapy with a pulsed infrared laser accelerates second-degree burn healing in rat: a clinical and microbiologic study. Photomed Laser Surg. 2010 Oct; 28(5):603-11. Ezzati A, Bayat M, Khoshvaghti A. PMID: 20860542.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    57. Higher-level motion detection deficit in Parkinson's disease. Brain Res. 2010 Mar 12; 1320:143-51. Ezzati A, Khadjevand F, Zandvakili A, Abbassian A. PMID: 20083093.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    58. Low-level laser therapy with pulsed infrared laser accelerates third-degree burn healing process in rats. J Rehabil Res Dev. 2009; 46(4):543-54. Ezzati A, Bayat M, Taheri S, Mohsenifar Z. PMID: 19882488.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    59. Topography of the motion aftereffect with and without eye movements. J Vis. 2008 Dec 18; 8(14):23.1-16. Ezzati A, Golzar A, Afraz AS. PMID: 19146324.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
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