Yousuke Horikawa

Title(s)Associate Health Sciences Professor, Pediatrics
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Reply to Su et al. Comment on "Matsumoto et al. Remimazolam's Effects on Postoperative Nausea and Vomiting Are Similar to Those of Propofol after Laparoscopic Gynecological Surgery: A Randomized Controlled Trial. J. Clin. Med. 2023, 12, 5402". J Clin Med. 2024 Feb 09; 13(4). Matsumoto A, Satomi S, Kakuta N, Narasaki S, Toyota Y, Miyoshi H, Horikawa YT, Saeki N, Tanaka K, Tsutsumi YM. PMID: 38398315; PMCID: PMC10889432.
      View in: PubMed   Mentions:
    2. Remimazolam-based anesthesia with flumazenil allows faster emergence than propofol-based anesthesia in older patients undergoing spinal surgery: A randomized controlled trial. Medicine (Baltimore). 2023 Nov 17; 102(46):e36081. Toyota Y, Kondo T, Oshita K, Haraki T, Narasaki S, Kido K, Kamiya S, Nakamura R, Saeki N, Horikawa YT, Tsutsumi YM. PMID: 37986333; PMCID: PMC10659722.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    3. Delayed Nonimmune Anaphylaxis Caused by Ropivacaine for Preoperative Nerve Blocks: A Case Report. A A Pract. 2023 Nov 01; 17(11):e01727. Ishii T, Miyoshi H, Kubo T, Tsutsumi YM, Horikawa YT, Tanaka H. PMID: 37948548.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Effects of Remimazolam on Intracellular Calcium Dynamics in Myotubes Derived from Patients with Malignant Hyperthermia and Functional Analysis of Type 1 Ryanodine Receptor Gene Variants. Genes (Basel). 2023 10 27; 14(11). Miyoshi H, Otsuki S, Mukaida K, Kido K, Sumii A, Ikeda T, Noda Y, Yasuda T, Narasaki S, Kato T, Kamiya S, Horikawa YT, Tsutsumi YM. PMID: 38002952; PMCID: PMC10671487.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    5. Remimazolam's Effects on Postoperative Nausea and Vomiting Are Similar to Those of Propofol after Laparoscopic Gynecological Surgery: A Randomized Controlled Trial. J Clin Med. 2023 Aug 20; 12(16). Matsumoto A, Satomi S, Kakuta N, Narasaki S, Toyota Y, Miyoshi H, Horikawa YT, Saeki N, Tanaka K, Tsutsumi YM. PMID: 37629444; PMCID: PMC10455908.
      View in: PubMed   Mentions: 5  
    6. Perioperative Management of Recurrent Hemophagocytic Syndrome in a Pregnant Woman: A Case Report. Am J Case Rep. 2023 Mar 21; 24:e939369. Sumii A, Miyoshi H, Kato T, Otsuki S, Horikawa YT, Satomi S, Saeki N, Tsutsumi YM. PMID: 36944584; PMCID: PMC10037114.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Rapid Dantrolene Administration with Body Temperature Monitoring Is Associated with Decreased Mortality in Japanese Malignant Hyperthermia Events. Biomed Res Int. 2023; 2023:8340209. Toyota Y, Kondo T, Shorin D, Sumii A, Kido K, Watanabe T, Otsuki S, Kanzaki R, Miyoshi H, Yasuda T, Horikawa YT, Mukaida K, Tsutsumi YM. PMID: 36874927; PMCID: PMC9977521.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. Remimazolam Requires Less Vasopressor Support during Induction and Maintenance of General Anesthesia in Patients with Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Retrospective Analysis from a Single Center. Biomed Res Int. 2022; 2022:6386606. Miyoshi H, Watanabe T, Kido K, Kamiya S, Otsuki S, Narasaki S, Toyota Y, Kondo T, Horikawa YT, Saeki N, Tsutsumi YM. PMID: 36317114; PMCID: PMC9617702.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    9. Assessment of postoperative nutritional status and physical function between open surgical aortic valve replacement and transcatheter aortic valve implantation in elderly patients. J Med Invest. 2020; 67(1.2):139-144. Sebe M, Tsutsumi R, Oyama T, Horikawa YT, Uemura Y, Kakuta N, Sakai Y, Morio A, Miyoshi H, Kondo T, Urabe T, Noda Y, Kamiya S, Saeki N, Kuroda M, Tanaka K, Tsutsumi YM, Sakaue H. PMID: 32378597.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Deletion of caveolin scaffolding domain alters cancer cell migration. Cell Cycle. 2019 06; 18(11):1268-1280. Okada S, Raja SA, Okerblom J, Boddu A, Horikawa Y, Ray S, Okada H, Kawamura I, Murofushi Y, Murray F, Patel HH. PMID: 31116089; PMCID: PMC6592257.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    11. Effect of oral carbohydrate with amino acid solution on serum oxidative/anti-oxidative status in healthy volunteers. J Anesth. 2017 Jun; 31(3):472-475. Tsutsumi YM, Oyama T, Kakuta N, Horikawa YT, Kume K, Sakai Y, Tsutsumi R, Tanaka K. PMID: 28421317.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Anxiety Associated with Asthma Exacerbations and Overuse of Medication: The Role of Cultural Competency. J Dev Behav Pediatr. 2017 Feb/Mar; 38 Suppl 1:S56-S59. Horikawa YT, Udaka TY, Crow JK, Takayama JI, Stein MT. PMID: 28141723.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Plasma substance P concentrations in patients undergoing general anesthesia: an objective marker associated with postoperative nausea and vomiting. JA Clin Rep. 2016; 2(1):9. Kadota T, Kakuta N, Horikawa YT, Tsutsumi R, Oyama T, Tanaka K, Tsutsumi YM. PMID: 29497664; PMCID: PMC5818727.
      View in: PubMed   Mentions: 1  
    14. Electrophysiology and metabolism of caveolin-3-overexpressing mice. Basic Res Cardiol. 2016 May; 111(3):28. Schilling JM, Horikawa YT, Zemljic-Harpf AE, Vincent KP, Tyan L, Yu JK, McCulloch AD, Balijepalli RC, Patel HH, Roth DM. PMID: 27023865; PMCID: PMC5336321.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    15. Geranylgeranylacetone and volatile anesthetic-induced cardiac protection synergism is dependent on caveolae and caveolin-3. J Anesth. 2014 Oct; 28(5):733-9. Tsutsumi YM, Tsutsumi R, Horikawa YT, Sakai Y, Hamaguchi E, Kitahata H, Kasai A, Kambe N, Tanaka K. PMID: 24633659.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    16. Geranylgeranylacetone protects the heart via caveolae and caveolin-3. Life Sci. 2014 Apr 17; 101(1-2):43-8. Tsutsumi YM, Tsutsumi R, Horikawa YT, Sakai Y, Hamaguchi E, Ishikawa Y, Yokoyama U, Kasai A, Kambe N, Tanaka K. PMID: 24582814.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    17. Whey Peptide-Based Formulas With ω-3 Fatty Acids Are Protective in Lipopolysaccharide-Mediated Sepsis. JPEN J Parenter Enteral Nutr. 2015 Jul; 39(5):552-61. Tsutsumi R, Horikawa YT, Kume K, Tanaka K, Kasai A, Kadota T, Tsutsumi YM. PMID: 24492312.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    18. Anxiety associated with asthma exacerbations and overuse of medication: the role of cultural competency. J Dev Behav Pediatr. 2014 Feb-Mar; 35(2):154-7. Horikawa YT, Udaka TY, Crow JK, Takayama JI, Stein MT. PMID: 24509059.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Signaling epicenters: the role of caveolae and caveolins in volatile anesthetic induced cardiac protection. Curr Pharm Des. 2014; 20(36):5681-9. Horikawa YT, Tsutsumi YM, Patel HH, Roth DM. PMID: 24502576; PMCID: PMC4119864.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    20. Albumin-normalized serum zinc: a clinically useful parameter for detecting taste impairment in patients undergoing dialysis. Nutr Res. 2014 Jan; 34(1):11-6. Tsutsumi R, Ohashi K, Tsutsumi YM, Horikawa YT, Minakuchi J, Minami S, Harada N, Sakaue H, Sakai T, Nakaya Y. PMID: 24418241.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Decline in anthropometric evaluation predicts a poor prognosis in geriatric patients. Asia Pac J Clin Nutr. 2012; 21(1):44-51. Tsutsumi R, Tsutsumi YM, Horikawa YT, Takehisa Y, Hosaka T, Harada N, Sakai T, Nakaya Y. PMID: 22374559.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. Volatile anesthetics protect cancer cells against tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via caveolins. Anesthesiology. 2011 Sep; 115(3):499-508. Kawaraguchi Y, Horikawa YT, Murphy AN, Murray F, Miyanohara A, Ali SS, Head BP, Patel PM, Roth DM, Patel HH. PMID: 21862885; PMCID: PMC3162469.
      View in: PubMed   Mentions: 33     Fields:    
    23. General anesthesia for electroconvulsive therapy with Brugada electrocardiograph pattern. J Med Invest. 2011 Aug; 58(3-4):273-6. Tsutsumi YM, Tomiyama Y, Horikawa YT, Sakai Y, Ohshita N, Tanaka K, Oshita S. PMID: 21921431.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    24. Neurokinin-1 receptor antagonism, aprepitant, effectively diminishes post-operative nausea and vomiting while increasing analgesic tolerance in laparoscopic gynecological procedures. J Med Invest. 2011 Aug; 58(3-4):246-51. Kakuta N, Tsutsumi YM, Horikawa YT, Kawano H, Kinoshita M, Tanaka K, Oshita S. PMID: 21921426.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    25. Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling. J Am Coll Cardiol. 2011 May 31; 57(22):2273-83. Horikawa YT, Panneerselvam M, Kawaraguchi Y, Tsutsumi YM, Ali SS, Balijepalli RC, Murray F, Head BP, Niesman IR, Rieg T, Vallon V, Insel PA, Patel HH, Roth DM. PMID: 21616289; PMCID: PMC3236642.
      View in: PubMed   Mentions: 56     Fields:    
    26. Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on delta-opioid receptor stimulation. Am J Physiol Heart Circ Physiol. 2010 Nov; 299(5):H1604-9. Panneerselvam M, Tsutsumi YM, Bonds JA, Horikawa YT, Saldana M, Dalton ND, Head BP, Patel PM, Roth DM, Patel HH. PMID: 20833967; PMCID: PMC2993198.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    27. Role of caveolin-3 and glucose transporter-4 in isoflurane-induced delayed cardiac protection. Anesthesiology. 2010 May; 112(5):1136-45. Tsutsumi YM, Kawaraguchi Y, Horikawa YT, Niesman IR, Kidd MW, Chin-Lee B, Head BP, Patel PM, Roth DM, Patel HH. PMID: 20418694; PMCID: PMC2860616.
      View in: PubMed   Mentions: 28     Fields:    
    28. Cardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioning. Circulation. 2008 Nov 04; 118(19):1979-88. Tsutsumi YM, Horikawa YT, Jennings MM, Kidd MW, Niesman IR, Yokoyama U, Head BP, Hagiwara Y, Ishikawa Y, Miyanohara A, Patel PM, Insel PA, Patel HH, Roth DM. PMID: 18936328; PMCID: PMC2676165.
      View in: PubMed   Mentions: 67     Fields:    
    29. Caveolin-3 expression and caveolae are required for isoflurane-induced cardiac protection from hypoxia and ischemia/reperfusion injury. J Mol Cell Cardiol. 2008 Jan; 44(1):123-30. Horikawa YT, Patel HH, Tsutsumi YM, Jennings MM, Kidd MW, Hagiwara Y, Ishikawa Y, Insel PA, Roth DM. PMID: 18054955; PMCID: PMC2701396.
      View in: PubMed   Mentions: 52     Fields:    
    30. Reactive oxygen species trigger ischemic and pharmacological postconditioning: in vivo and in vitro characterization. Life Sci. 2007 Sep 22; 81(15):1223-7. Tsutsumi YM, Yokoyama T, Horikawa Y, Roth DM, Patel HH. PMID: 17915258; PMCID: PMC2080844.
      View in: PubMed   Mentions: 49     Fields:    
    31. Fluorescent method for detection of cleaved collagens using O-phthaldialdehyde (OPA). J Biochem Biophys Methods. 2008 Apr 24; 70(6):878-82. Go K, Horikawa Y, Garcia R, Villarreal FJ. PMID: 17573117; PMCID: PMC2836792.
      View in: PubMed   Mentions: 6     Fields:    
    32. Mechanisms of cardiac protection from ischemia/reperfusion injury: a role for caveolae and caveolin-1. FASEB J. 2007 May; 21(7):1565-74. Patel HH, Tsutsumi YM, Head BP, Niesman IR, Jennings M, Horikawa Y, Huang D, Moreno AL, Patel PM, Insel PA, Roth DM. PMID: 17272740.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
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