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A Pilot Study of Pembrolizumab Combined With Stereotactic Ablative Radiotherapy for Patients With Advanced or Metastatic Sarcoma. Cancer Control. 2024 Jan-Dec; 31:10732748241237331.
Harris JP, Park J, Ku E, Seyedin S, Stitzlein R, Goldin A, Chen WP, McLaren C, Chen AM, Chow W. PMID: 38449377; PMCID: PMC10919132.
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Translation:
HumansCTClinical Trials
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Therapy With Metronomic Cyclophosphamide (mCyc) for Previously-Treated Metastatic Castrate-Resistant Prostate Cancer (mCRPC). Clin Genitourin Cancer. 2023 Nov 07.
Mar N, Dwabe S, Baranda MN, Zarrabi KK, Eturi A, Gulati S, Parikh M, Seyedin SN, Kalebasty AR. PMID: 38087703.
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Humans
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The Correlation Between Lymphocyte Nadir and Radiation Therapy for Soft Tissue Sarcoma: Defining Key Dosimetric Parameters and Outlining Clinical Significance. Adv Radiat Oncol. 2024 Jan; 9(1):101309.
Ku E, Harada G, Chiao E, Rao P, Hosseinian S, Seyedin S, Healy E, Maxim P, Chow W, Stitzlein R, Limoli C, Harris J. PMID: 38260229; PMCID: PMC10801664.
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PubMed Mentions:
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Nanotechnology and machine learning enable circulating tumor cells as a reliable biomarker for radiotherapy responses of gastrointestinal cancer patients. Biosens Bioelectron. 2023 Apr 15; 226:115117.
Poellmann MJ, Bu J, Liu S, Wang AZ, Seyedin SN, Chandrasekharan C, Hong H, Kim Y, Caster JM, Hong S. PMID: 36753988; PMCID: PMC10034717.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Combination of Pembrolizumab and Stereotactic Body Radiation Therapy in Recurrent Metastatic Penile Squamous Cell Carcinoma: A Case Study. Biomedicines. 2022 Nov 24; 10(12).
Kaakour D, Seyedin S, Houshyar R, Mar N. PMID: 36551787.
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PubMed Mentions:
1
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The potential of biology-guided radiation therapy in thoracic cancer: A preliminary treatment planning study. Front Oncol. 2022; 12:921473.
Seyedin SN, Bassalow R, Mawlawi OR, Turner LM, Patel RR, Mazin SR, Oderinde OM, Voronenko Y, Wages CA, Olcott PD, Chang JY, Balter PA, Welsh JW. PMID: 36313653; PMCID: PMC9613936.
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PubMed Mentions:
1
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A phase Ib feasibility trial of response adapted neoadjuvant therapy in gastric cancer (RANT-GC). Future Oncol. 2022 Jul; 18(21):2615-2622.
Dayyani F, Smith BR, Nguyen NT, Daly S, Hinojosa MW, Seyedin SN, Kuo J, Samarasena JB, Lee JG, Taylor TH, Cho MT, Senthil M. PMID: 35603628; PMCID: PMC9437768.
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Translation:
Humans
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Controversies in Lung Cancer: Heterogeneity in Treatment Recommendations for Stage III NSCLC According to Disease Burden and Oncogenic Driver Alterations. Clin Lung Cancer. 2022 06; 23(4):333-344.
Harris JP, Fujimoto DK, Nagasaka M, Ku E, Harada G, Keshava H, Mahtabifard A, Longoria J, Patel N, Seyedin S, Simon A, Chen A. PMID: 35256282.
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Translation:
Humans
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A Recursive Partitioning Analysis Demonstrating Risk Subsets for 8-Year Biochemical Relapse After Margin-Positive Radical Prostatectomy Without Adjuvant Hormone or Radiation Therapy. Adv Radiat Oncol. 2021 Nov-Dec; 6(6):100778.
Seyedin SN, Watkins JM, Mayo Z, Snow AN, Laszewski M, Russo JK, Mott SL, Tracy CR, Smith MC, Buatti JM, Caster JM. PMID: 34934861; PMCID: PMC8655410.
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PubMed Mentions:
1
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The Role of Definitive Radiation and Surgery in Metastatic Esophageal Cancer: An NCDB Investigation. Ann Thorac Surg. 2021 08; 112(2):459-466.
Seyedin SN, Parekh KR, Ginader T, Caster JM. PMID: 33096068.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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The Effect of Concurrent Stereotactic Body Radiation and Anti-PD-1 Therapy for Recurrent Metastatic Sarcoma. Radiat Res. 2020 08 01; 194(2):124-132.
Callaghan CM, Seyedin SN, Mohiuddin IH, Hawkes KL, Petronek MS, Anderson CM, Buatti JM, Milhem MM, Monga V, Allen BG. PMID: 32845986; PMCID: PMC10443123.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Safety and Efficacy of Stereotactic Body Radiation Therapy for Locoregional Recurrences After Prior Chemoradiation for Advanced Esophageal Carcinoma. Front Oncol. 2020; 10:1311.
Seyedin SN, Gannon MK, Plichta KA, Abushahin L, Berg DJ, Arshava EV, Parekh KR, Keech JC, Caster JM, Welsh JW, Allen BG. PMID: 32850412; PMCID: PMC7412633.
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PubMed Mentions:
1
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Local management of preinvasive and clinical T1-3 penile cancer: utilization of diverse treatment modalities. Future Oncol. 2020 May; 16(14):955-960.
Menon H, Patel RR, Ludmir EB, Muralidhar V, Cushman TR, Amini A, Seyedin SN, Nguyen PL, Verma V. PMID: 32301342.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Management and outcomes of primary anorectal melanoma in the United States. Future Oncol. 2020 Mar; 16(8):329-338.
Menon H, Patel RR, Cushman TR, Amini A, Seyedin SN, Adams AC, Lin C, Verma V. PMID: 32067486.
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PubMed Mentions:
5 Fields:
Translation:
HumansPHPublic Health
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Combination Therapy with Radiation and PARP Inhibition Enhances Responsiveness to Anti-PD-1 Therapy in Colorectal Tumor Models. Int J Radiat Oncol Biol Phys. 2020 09 01; 108(1):81-92.
Seyedin SN, Hasibuzzaman MM, Pham V, Petronek MS, Callaghan C, Kalen AL, Mapuskar KA, Mott SL, Spitz DR, Allen BG, Caster JM. PMID: 32036006; PMCID: PMC7416439.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Deep segmentation networks predict survival of non-small cell lung cancer. Sci Rep. 2019 11 21; 9(1):17286.
Baek S, He Y, Allen BG, Buatti JM, Smith BJ, Tong L, Sun Z, Wu J, Diehn M, Loo BW, Plichta KA, Seyedin SN, Gannon M, Cabel KR, Kim Y, Wu X. PMID: 31754135; PMCID: PMC6872742.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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Results of a Phase 1/2 Trial of Chemoradiotherapy With Simultaneous Integrated Boost of Radiotherapy Dose in Unresectable Locally Advanced Esophageal Cancer. JAMA Oncol. 2019 11 01; 5(11):1597-1604.
Chen D, Menon H, Verma V, Seyedin SN, Ajani JA, Hofstetter WL, Nguyen QN, Chang JY, Gomez DR, Amini A, Swisher SG, Blum MA, Younes AI, Barsoumian HB, Erasmus JJ, Lee JH, Bhutani MS, Hess KR, Minsky BD, Welsh JW. PMID: 31529018; PMCID: PMC6749545.
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PubMed Mentions:
35 Fields:
Translation:
HumansCTClinical Trials
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First-in-Human Phase I Clinical Trial of Pharmacologic Ascorbate Combined with Radiation and Temozolomide for Newly Diagnosed Glioblastoma. Clin Cancer Res. 2019 11 15; 25(22):6590-6597.
Allen BG, Bodeker KL, Smith MC, Monga V, Sandhu S, Hohl R, Carlisle T, Brown H, Hollenbeck N, Vollstedt S, Greenlee JD, Howard MA, Mapuskar KA, Seyedin SN, Caster JM, Jones KA, Cullen JJ, Berg D, Wagner BA, Buettner GR, TenNapel MJ, Smith BJ, Spitz DR, Buatti JM. PMID: 31427282; PMCID: PMC6858950.
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PubMed Mentions:
40 Fields:
Translation:
HumansCTClinical Trials
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Optimizing Advances in Nanoparticle Delivery for Cancer Immunotherapy. Adv Drug Deliv Rev. 2019 04; 144:3-15.
Caster JM, Callaghan C, Seyedin SN, Henderson K, Sun B, Wang AZ. PMID: 31330165.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Clinical Utility of Pretreatment and 3-Month 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Standardized Uptake Value in Predicting and Assessing Recurrence in T3-T4 Laryngeal Carcinoma Treated With Definitive Radiation. Ann Otol Rhinol Laryngol. 2019 Jul; 128(7):595-600.
Mayo Z, Seyedin SN, Mallak N, Mott SL, Menda Y, Graham M, Anderson C. PMID: 30808209.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Cutaneous malignant melanoma of the oral cavity following skin graft reconstruction: Case report. Head Neck. 2019 02; 41(2):E26-E29.
Mayo Z, Seyedin S, Marquardt M, Mohiuddin I, Milhem M, Liu V, Pagedar N, Anderson C. PMID: 30537068.
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PubMed Mentions: Fields:
Translation:
Humans
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Is More Always Better? An Assessment of the Impact of Lymph Node Yield on Outcome for Clinically Localized Prostate Cancer with Low/Intermediate Risk Pathology (pT2-3a/pN0) Managed with Prostatectomy Alone. Pathol Oncol Res. 2019 Jan; 25(1):209-215.
Seyedin SN, Mitchell DL, Mott SL, Russo JK, Tracy CR, Snow AN, Parkhurst JR, Smith MC, Buatti JM, Watkins JM. PMID: 29079967; PMCID: PMC5924586.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation. Transl Lung Cancer Res. 2017 Apr; 6(2):148-158.
Schoenhals JE, Seyedin SN, Anderson C, Brooks ED, Li YR, Younes AI, Niknam S, Li A, Barsoumian HB, Cortez MA, Welsh JW. PMID: 28529897; PMCID: PMC5420535.
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PubMed Mentions:
17
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Local Control and Toxicity of a Simultaneous Integrated Boost for Dose Escalation in Locally Advanced Esophageal Cancer: Interim Results from a Prospective Phase I/II Trial. J Thorac Oncol. 2017 02; 12(2):375-382.
Welsh JW, Seyedin SN, Allen PK, Hofstetter WL, Ajani JA, Chang JY, Gomez DR, Amini A, Swisher SG, Blum MA, Younes AI, Nguyen QN, Minsky BD, Erasmus JJ, Lee JH, Bhutani M, Komaki RU. PMID: 27794500.
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PubMed Mentions:
33 Fields:
Translation:
HumansCTClinical Trials
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Preclinical Rationale and Clinical Considerations for Radiotherapy Plus Immunotherapy: Going Beyond Local Control. Cancer J. 2016 Mar-Apr; 22(2):130-7.
Schoenhals JE, Seyedin SN, Tang C, Cortez MA, Niknam S, Tsouko E, Chang JY, Hahn SM, Welsh JW. PMID: 27111909.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Strategies for combining immunotherapy with radiation for anticancer therapy. Immunotherapy. 2015; 7(9):967-980.
Seyedin SN, Schoenhals JE, Lee DA, Cortez MA, Wang X, Niknam S, Tang C, Hong DS, Naing A, Sharma P, Allison JP, Chang JY, Gomez DR, Heymach JV, Komaki RU, Cooper LJ, Welsh JW. PMID: 26310908; PMCID: PMC4825325.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Author's view: radiation and immunotherapy as systemic therapy for solid tumors. Oncoimmunology. 2015 Jan; 4(3):e986402.
Seyedin SN, Tang C, Welsh JW. PMID: 25949899; PMCID: PMC4404906.
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PubMed Mentions:
6 Fields:
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Galectin-1 and immune suppression during radiotherapy. Clin Cancer Res. 2014 Dec 15; 20(24):6230-2.
Welsh JW, Seyedin SN, Cortez MA, Maity A, Hahn SM. PMID: 25348514.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Combining radiation and immunotherapy: a new systemic therapy for solid tumors? Cancer Immunol Res. 2014 Sep; 2(9):831-8.
Tang C, Wang X, Soh H, Seyedin S, Cortez MA, Krishnan S, Massarelli E, Hong D, Naing A, Diab A, Gomez D, Ye H, Heymach J, Komaki R, Allison JP, Sharma P, Welsh JW. PMID: 25187273; PMCID: PMC5367158.
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PubMed Mentions:
148 Fields:
Translation:
HumansAnimals
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Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways. PLoS One. 2010 Dec 30; 5(12):e15805.
Wang J, Taherbhoy AM, Hunt HW, Seyedin SN, Miller DW, Miller DJ, Huang DT, Schulman BA. PMID: 21209884; PMCID: PMC3012696.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol Cell. 2009 Oct 09; 36(1):39-50.
Zhuang M, Calabrese MF, Liu J, Waddell MB, Nourse A, Hammel M, Miller DJ, Walden H, Duda DM, Seyedin SN, Hoggard T, Harper JW, White KP, Schulman BA. PMID: 19818708; PMCID: PMC2847577.
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PubMed Mentions:
251 Fields:
Translation:
HumansAnimalsCells
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The mechanism of ATP-dependent primer-template recognition by a clamp loader complex. Cell. 2009 May 15; 137(4):659-71.
Simonetta KR, Kazmirski SL, Goedken ER, Cantor AJ, Kelch BA, McNally R, Seyedin SN, Makino DL, O'Donnell M, Kuriyan J. PMID: 19450514; PMCID: PMC2684988.
View in:
PubMed Mentions:
83 Fields:
Translation:
Cells