Stephen C Bondy

Title(s)Professor, Community and Environmental Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(949) 824-8077, 5432
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    FREE RADICALS IN MENTAL HEALTH &NEUROBIOLOGY
    NIH R13NS042619Jun 15, 2001 - May 31, 2006
    Role: Principal Investigator
    Neurodegenration and Mitochnodrial Dysfunction in Aging
    NIH R01AG016794Apr 1, 1999 - Mar 31, 2010
    Role: Principal Investigator
    ALUMINUM/IRON INTERACTIONS IN NEURODEGENERATIVE DISEASE
    NIH R01ES007992May 1, 1996 - Apr 30, 2007
    Role: Principal Investigator
    MITIGATION OF THE ADVERSE EFFECTS OF ETHANOL IN THE CNS
    NIH R01AA008281Aug 1, 1991 - Jul 31, 1997
    Role: Principal Investigator
    EFFECT OF NEUROTOXIC AGENTS ON SYNPTOSOMAL INTEGRITY
    NIH R01ES004071Aug 1, 1987 - Jul 31, 1990
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Can a Micronutrient Mixture Delay the Onset and Progression of Symptoms of Single-Point Mutation Diseases? J Am Coll Nutr. 2021 Jul 06; 1-10. Prasad KN, Bondy SC. PMID: 34227926.
      View in: PubMed   Mentions:    Fields:    
    2. Alternatives to Insulin for the Regulation of Blood Sugar Levels in Type 2 Diabetes. Int J Mol Sci. 2020 Nov 05; 21(21). Bondy SC, Wu M, Prasad KN. PMID: 33167495.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Attenuation of acute and chronic inflammation using compounds derived from plants. Exp Biol Med (Maywood). 2021 02; 246(4):406-413. Bondy SC, Wu M, Prasad KN. PMID: 33023332.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Distinctive cellular response to aluminum based adjuvants. Environ Toxicol Pharmacol. 2020 Aug; 78:103404. Nies I, Hidalgo K, Bondy SC, Campbell A. PMID: 32388105.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Aspects of the immune system that impact brain function. J Neuroimmunol. 2020 03 15; 340:577167. Bondy SC. PMID: 32000018.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    6. Melatonin and Regulation of Immune Function: Impact on Numerous Diseases. Curr Aging Sci. 2020; 13(2):92-101. Bondy SC, Campbell A. PMID: 32651969.
      View in: PubMed   Mentions: 2     Fields:    
    7. Increased oxidative stress, inflammation, and glutamate: Potential preventive and therapeutic targets for hearing disorders. Mech Ageing Dev. 2020 01; 185:111191. Prasad KN, Bondy SC. PMID: 31765645.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    8. A paradigm shift at the heart of occupational health. Toxicol Ind Health. 2019 Sep; 35(9):567. Bondy SC. PMID: 31570061.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Oxidative and Inflammatory Events in Prion Diseases: Can They Be Therapeutic Targets? Curr Aging Sci. 2019; 11(4):216-225. Prasad KN, Bondy SC. PMID: 30636622.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    10. Dietary Fibers and Their Fermented Short-Chain Fatty Acids in Prevention of Human Diseases. Mech Ageing Dev. 2018 Oct 15. Prasad KN, Bondy SC. PMID: 30336163.
      View in: PubMed   Mentions: 8     Fields:    
    11. Mechanisms Underlying Tumor Suppressive Properties of Melatonin. Int J Mol Sci. 2018 Jul 27; 19(8). Bondy SC, Campbell A. PMID: 30060531.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    12. Environmental and Dietary Exposure to Copper and Its Cellular Mechanisms Linking to Alzheimer's Disease. Toxicol Sci. 2018 06 01; 163(2):338-345. Hsu HW, Bondy SC, Kitazawa M. PMID: 29409005.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
    13. Water Quality and Brain Function. Int J Environ Res Public Health. 2017 12 21; 15(1). Bondy SC, Campbell A. PMID: 29267198.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    14. MicroRNAs in Hearing Disorders: Their Regulation by Oxidative Stress, Inflammation and Antioxidants. Front Cell Neurosci. 2017; 11:276. Prasad KN, Bondy SC. PMID: 28955205.
      View in: PubMed   Mentions:
    15. Telomere shortening during aging: Attenuation by antioxidants and anti-inflammatory agents. Mech Ageing Dev. 2017 06; 164:61-66. Prasad KN, Wu M, Bondy SC. PMID: 28431907.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    16. Exposure to ambient ultrafine particulate matter alters the expression of genes in primary human neurons. Neurotoxicology. 2017 01; 58:50-57. Solaimani P, Saffari A, Sioutas C, Bondy SC, Campbell A. PMID: 27851901.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    17. Anthropogenic pollutants may increase the incidence of neurodegenerative disease in an aging population. Toxicology. 2016 Feb 03; 341-343:41-6. Bondy SC. PMID: 26812399.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. Inhibition of Early Biochemical Defects in Prodromal Huntington's Disease by Simultaneous Activation of Nrf2 and Elevation of Multiple Micronutrients. Curr Aging Sci. 2016; 9(1):61-70. Prasad KN, Bondy SC. PMID: 26601664.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    19. Low levels of aluminum can lead to behavioral and morphological changes associated with Alzheimer's disease and age-related neurodegeneration. Neurotoxicology. 2016 Jan; 52:222-9. Bondy SC. PMID: 26687397.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsPHPublic Health
    20. Common biochemical defects linkage between post-traumatic stress disorders, mild traumatic brain injury (TBI) and penetrating TBI. Brain Res. 2015 Mar 02; 1599:103-14. Prasad KN, Bondy SC. PMID: 25553619.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    21. Inhibition of early upstream events in prodromal Alzheimer's disease by use of targeted antioxidants. Curr Aging Sci. 2014; 7(2):77-90. Prasad KN, Bondy SC. PMID: 25101711.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    22. Protective effect of Tanshinone IIA against infarct size and increased HMGB1, NF?B, GFAP and apoptosis consequent to transient middle cerebral artery occlusion. Neurochem Res. 2014 Feb; 39(2):295-304. Wang JG, Bondy SC, Zhou L, Yang FZ, Ding ZG, Hu Y, Tian Y, Wen PY, Luo H, Wang F, Li WW, Zhou J. PMID: 24362639.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    23. Evaluation of role of oxidative stress on aging in Caenorhabditis elegans: a brief review. Curr Aging Sci. 2013 Dec; 6(3):215-9. Prasad KN, Bondy SC. PMID: 23782003.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    24. Prolonged exposure to low levels of aluminum leads to changes associated with brain aging and neurodegeneration. Toxicology. 2014 Jan 06; 315:1-7. Bondy SC. PMID: 24189189.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsPHPublic Health
    25. Melatonin decreases levels of S100ß and NF?B, increases levels of synaptophysin in a rat model of Alzheimer's disease. Curr Aging Sci. 2013 Jul; 6(2):142-9. Jun Z, Li Z, Fang W, Fengzhen Y, Puyuan W, Wenwen L, Zhi S, Bondy SC. PMID: 23030129.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    26. Low concentrations of copper in drinking water increase AP-1 binding in the brain. Toxicol Ind Health. 2015 Dec; 31(12):1178-84. Lung S, Li H, Bondy SC, Campbell A. PMID: 23719850.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    27. Age-related differences in the response of the brain to dietary melatonin. Age (Dordr). 2014 Feb; 36(1):49-55. Campbell A, Sharman E, Bondy SC. PMID: 23695950.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    28. Nanoparticles and colloids as contributing factors in neurodegenerative disease. Int J Environ Res Public Health. 2011 06; 8(6):2200-11. Bondy SC. PMID: 21776226.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    29. Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease. Brain Res. 2011 May 04; 1388:141-7. Zhou J, Zhou L, Hou D, Tang J, Sun J, Bondy SC. PMID: 21377451.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    30. Extended exposure to dietary melatonin reduces tumor number and size in aged male mice. Exp Gerontol. 2011 Jan; 46(1):18-22. Sharman EH, Sharman KG, Bondy SC. PMID: 20837128.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    31. Melatonin alters age-related changes in transcription factors and kinase activation. Neurochem Res. 2010 Dec; 35(12):2035-42. Bondy SC, Li H, Zhou J, Wu M, Bailey JA, Lahiri DK. PMID: 20535557.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    32. The neurotoxicity of environmental aluminum is still an issue. Neurotoxicology. 2010 Sep; 31(5):575-81. Bondy SC. PMID: 20553758.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsPHPublic Health
    33. Melatonin causes gene expression in aged animals to respond to inflammatory stimuli in a manner differing from that of young animals. Curr Aging Sci. 2008 Dec; 1(3):152-8. Sharman EH, Sharman KG, Bondy SC. PMID: 20021386.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    34. Melatonin and the aging brain. Neurochem Int. 2007 Mar; 50(4):571-80. Bondy SC, Sharman EH. PMID: 17276551.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    35. Effects of melatonin and age on gene expression in mouse CNS using microarray analysis. Neurochem Int. 2007 Jan; 50(2):336-44. Sharman EH, Bondy SC, Sharman KG, Lahiri D, Cotman CW, Perreau VM. PMID: 17118492.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    36. Aluminum and copper in drinking water enhance inflammatory or oxidative events specifically in the brain. J Neuroimmunol. 2006 Jul; 176(1-2):16-23. Becaria A, Lahiri DK, Bondy SC, Chen D, Hamadeh A, Li H, Taylor R, Campbell A. PMID: 16697052.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    37. Decreased expression of inflammation-related genes following inhalation exposure to manganese. Neurotoxicology. 2006 May; 27(3):395-401. HaMai D, Rinderknecht AL, Guo-Sharman K, Kleinman MT, Bondy SC. PMID: 16476481.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsPHPublic Health
    38. Parallel changes in gene expression in aged human and mouse cortex. Neurosci Lett. 2005 Dec 16; 390(1):4-8. Sharman EH, Sharman KG, Bondy SC. PMID: 16112455.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    39. Developmental neurotoxicology. J Neurosci Res. 2005 Sep 01; 81(5):605-12. Bondy SC, Campbell A. PMID: 16035107.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    40. Potential occupational risks for neurodegenerative diseases. Am J Ind Med. 2005 Jul; 48(1):63-77. Park RM, Schulte PA, Bowman JD, Walker JT, Bondy SC, Yost MG, Touchstone JA, Dosemeci M. PMID: 15940722.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansPHPublic Health
    41. Retardation of brain aging by chronic treatment with melatonin. Ann N Y Acad Sci. 2004 Dec; 1035:197-215. Bondy SC, Lahiri DK, Perreau VM, Sharman KZ, Campbell A, Zhou J, Sharman EH. PMID: 15681809.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    42. Melatonin, metals, and gene expression: implications in aging and neurodegenerative disorders. Ann N Y Acad Sci. 2004 Dec; 1035:216-30. Lahiri DK, Chen D, Lahiri P, Rogers JT, Greig NH, Bondy S. PMID: 15681810.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    43. Age-related changes in serum melatonin in mice: higher levels of combined melatonin and 6-hydroxymelatonin sulfate in the cerebral cortex than serum, heart, liver and kidney tissues. J Pineal Res. 2004 May; 36(4):217-23. Lahiri DK, Ge YW, Sharman EH, Bondy SC. PMID: 15066045.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    44. Dietary supplementation with melatonin reduces levels of amyloid beta-peptides in the murine cerebral cortex. J Pineal Res. 2004 May; 36(4):224-31. Lahiri DK, Chen D, Ge YW, Bondy SC, Sharman EH. PMID: 15066046.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    45. Age-related changes in murine CNS mRNA gene expression are modulated by dietary melatonin. J Pineal Res. 2004 Apr; 36(3):165-70. Sharman EH, Sharman KG, Ge YW, Lahiri DK, Bondy SC. PMID: 15009506.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    46. Pro- or anti-oxidant manganese: a suggested mechanism for reconciliation. Neurochem Int. 2004 Mar; 44(4):223-9. HaMai D, Bondy SC. PMID: 14602085.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    47. Oxidative basis of manganese neurotoxicity. Ann N Y Acad Sci. 2004 Mar; 1012:129-41. HaMai D, Bondy SC. PMID: 15105260.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    48. Aluminum and copper interact in the promotion of oxidative but not inflammatory events: implications for Alzheimer's disease. J Alzheimers Dis. 2003 Feb; 5(1):31-8. Becaria A, Bondy SC, Campbell A. PMID: 12590164.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    49. Dietary melatonin selectively reverses age-related changes in cortical cytokine mRNA levels, and their responses to an inflammatory stimulus. Neurobiol Aging. 2002 Jul-Aug; 23(4):633-8. Sharman KG, Sharman EH, Yang E, Bondy SC. PMID: 12009512.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    50. Pro-inflammatory effects of aluminum in human glioblastoma cells. Brain Res. 2002 Apr 12; 933(1):60-5. Campbell A, Yang EY, Tsai-Turton M, Bondy SC. PMID: 11929636.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    51. Dietary modulation of age-related changes in cerebral pro-oxidant status. Neurochem Int. 2002 Feb; 40(2):123-30. Bondy SC, Yang YE, Walsh TJ, Gie YW, Lahiri DK. PMID: 11738478.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    52. Exposure of mice to tobacco smoke attenuates the toxic effect of methamphetamine on dopamine systems. Toxicol Lett. 2000 Dec 20; 118(1-2):43-6. Bondy SC, Ali SF, Kleinman MT. PMID: 11137307.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsPHPublic Health
    53. Aluminum but not iron treatment induces pro-oxidant events in the rat brain. Mol Chem Neuropathol. 1998 Jun-Aug; 34(2-3):219-32. Bondy SC, Ali SF, Guo-Ross S. PMID: 10327419.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
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