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Bondy, Stephen C

TitleProfessor
InstitutionUniversity of California, Irvine
DepartmentCommunity and Environmental Medicine
Address1001 Health Sciences Road
CA 92697-3950
Phone(949) 824-8077, 5432
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    FREE RADICALS IN MENTAL HEALTH &NEUROBIOLOGY
    NIH/NINDS R13NS042619Jun 15, 2001 - May 31, 2006
    Role: Principal Investigator
    Neurodegenration and Mitochnodrial Dysfunction in Aging
    NIH/NIA R01AG016794Apr 1, 1999 - Mar 31, 2010
    Role: Principal Investigator
    ALUMINUM/IRON INTERACTIONS IN NEURODEGENERATIVE DISEASE
    NIH/NIEHS R01ES007992May 1, 1996 - Apr 30, 2007
    Role: Principal Investigator
    MITIGATION OF THE ADVERSE EFFECTS OF ETHANOL IN THE CNS
    NIH/NIAAA R01AA008281Aug 1, 1991 - Jul 31, 1997
    Role: Principal Investigator
    EFFECT OF NEUROTOXIC AGENTS ON SYNPTOSOMAL INTEGRITY
    NIH/NIEHS R01ES004071Aug 1, 1987 - Jul 31, 1990
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hsu HW, Bondy S, Kitazawa M. Environmental and dietary exposure to copper and its cellular mechanisms linking to Alzheimer disease. Toxicol Sci. 2018 Feb 02. PMID: 29409005.
      View in: PubMed
    2. Bondy S, Campbell A. Water Quality and Brain Function. Int J Environ Res Public Health. 2017 Dec 21; 15(1). PMID: 29267198.
      View in: PubMed
    3. Prasad KN, Bondy S. MicroRNAs in Hearing Disorders: Their Regulation by Oxidative Stress, Inflammation and Antioxidants. Front Cell Neurosci. 2017; 11:276. PMID: 28955205.
      View in: PubMed
    4. Prasad KN, Wu M, Bondy S. Telomere shortening during aging: Attenuation by antioxidants and anti-inflammatory agents. Mech Ageing Dev. 2017 06; 164:61-66. PMID: 28431907.
      View in: PubMed
    5. Solaimani P, Saffari A, Sioutas C, Bondy S, Campbell A. Exposure to ambient ultrafine particulate matter alters the expression of genes in primary human neurons. Neurotoxicology. 2017 01; 58:50-57. PMID: 27851901.
      View in: PubMed
    6. Bondy S. Anthropogenic pollutants may increase the incidence of neurodegenerative disease in an aging population. Toxicology. 2016 Feb 03; 341-343:41-6. PMID: 26812399.
      View in: PubMed
    7. Prasad KN, Bondy S. Inhibition of Early Biochemical Defects in Prodromal Huntington's Disease by Simultaneous Activation of Nrf2 and Elevation of Multiple Micronutrients. Curr Aging Sci. 2016; 9(1):61-70. PMID: 26601664.
      View in: PubMed
    8. Bondy S. Low levels of aluminum can lead to behavioral and morphological changes associated with Alzheimer's disease and age-related neurodegeneration. Neurotoxicology. 2016 Jan; 52:222-9. PMID: 26687397.
      View in: PubMed
    9. Prasad KN, Bondy S. Common biochemical defects linkage between post-traumatic stress disorders, mild traumatic brain injury (TBI) and penetrating TBI. Brain Res. 2015 Mar 02; 1599:103-14. PMID: 25553619.
      View in: PubMed
    10. Prasad KN, Bondy S. Inhibition of early upstream events in prodromal Alzheimer's disease by use of targeted antioxidants. Curr Aging Sci. 2014; 7(2):77-90. PMID: 25101711.
      View in: PubMed
    11. Wang JG, Bondy S, Zhou L, Yang FZ, Ding ZG, Hu Y, Tian Y, Wen PY, Luo H, Wang F, Li WW, Zhou J. Protective effect of Tanshinone IIA against infarct size and increased HMGB1, NF?B, GFAP and apoptosis consequent to transient middle cerebral artery occlusion. Neurochem Res. 2014 Feb; 39(2):295-304. PMID: 24362639.
      View in: PubMed
    12. Prasad KN, Bondy S. Evaluation of role of oxidative stress on aging in Caenorhabditis elegans: a brief review. Curr Aging Sci. 2013 Dec; 6(3):215-9. PMID: 23782003.
      View in: PubMed
    13. Bondy S. Prolonged exposure to low levels of aluminum leads to changes associated with brain aging and neurodegeneration. Toxicology. 2014 Jan 06; 315:1-7. PMID: 24189189.
      View in: PubMed
    14. Jun Z, Li Z, Fang W, Fengzhen Y, Puyuan W, Wenwen L, Zhi S, Bondy S. Melatonin decreases levels of S100ß and NF?B, increases levels of synaptophysin in a rat model of Alzheimer's disease. Curr Aging Sci. 2013 Jul; 6(2):142-9. PMID: 23030129.
      View in: PubMed
    15. Lung S, Li H, Bondy S, Campbell A. Low concentrations of copper in drinking water increase AP-1 binding in the brain. Toxicol Ind Health. 2015 Dec; 31(12):1178-84. PMID: 23719850.
      View in: PubMed
    16. Campbell A, Sharman E, Bondy S. Age-related differences in the response of the brain to dietary melatonin. Age (Dordr). 2014 Feb; 36(1):49-55. PMID: 23695950; PMCID: PMC3889890.
    17. Bondy S. Nanoparticles and colloids as contributing factors in neurodegenerative disease. Int J Environ Res Public Health. 2011 06; 8(6):2200-11. PMID: 21776226; PMCID: PMC3138021.
    18. Zhou J, Zhou L, Hou D, Tang J, Sun J, Bondy S. Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease. Brain Res. 2011 May 04; 1388:141-7. PMID: 21377451.
      View in: PubMed
    19. Sharman EH, Sharman KG, Bondy S. Extended exposure to dietary melatonin reduces tumor number and size in aged male mice. Exp Gerontol. 2011 Jan; 46(1):18-22. PMID: 20837128; PMCID: PMC2998564.
    20. Bondy S, Li H, Zhou J, Wu M, Bailey JA, Lahiri DK. Melatonin alters age-related changes in transcription factors and kinase activation. Neurochem Res. 2010 Dec; 35(12):2035-42. PMID: 20535557; PMCID: PMC3002167.
    21. Bondy S. The neurotoxicity of environmental aluminum is still an issue. Neurotoxicology. 2010 Sep; 31(5):575-81. PMID: 20553758; PMCID: PMC2946821.
    22. Sharman EH, Sharman KG, Bondy S. Melatonin causes gene expression in aged animals to respond to inflammatory stimuli in a manner differing from that of young animals. Curr Aging Sci. 2008 Dec; 1(3):152-8. PMID: 20021386.
      View in: PubMed
    23. Bondy S, Sharman EH. Melatonin and the aging brain. Neurochem Int. 2007 Mar; 50(4):571-80. PMID: 17276551.
      View in: PubMed
    24. Sharman EH, Bondy S, Sharman KG, Lahiri D, Cotman CW, Perreau VM. Effects of melatonin and age on gene expression in mouse CNS using microarray analysis. Neurochem Int. 2007 Jan; 50(2):336-44. PMID: 17118492; PMCID: PMC1868445.
    25. Becaria A, Lahiri DK, Bondy S, Chen D, Hamadeh A, Li H, Taylor R, Campbell A. Aluminum and copper in drinking water enhance inflammatory or oxidative events specifically in the brain. J Neuroimmunol. 2006 Jul; 176(1-2):16-23. PMID: 16697052.
      View in: PubMed
    26. HaMai D, Rinderknecht AL, Guo-Sharman K, Kleinman MT, Bondy S. Decreased expression of inflammation-related genes following inhalation exposure to manganese. Neurotoxicology. 2006 May; 27(3):395-401. PMID: 16476481.
      View in: PubMed
    27. Sharman EH, Sharman KG, Bondy S. Parallel changes in gene expression in aged human and mouse cortex. Neurosci Lett. 2005 Dec 16; 390(1):4-8. PMID: 16112455.
      View in: PubMed
    28. Bondy S, Campbell A. Developmental neurotoxicology. J Neurosci Res. 2005 Sep 01; 81(5):605-12. PMID: 16035107.
      View in: PubMed
    29. Park RM, Schulte PA, Bowman JD, Walker JT, Bondy S, Yost MG, Touchstone JA, Dosemeci M. Potential occupational risks for neurodegenerative diseases. Am J Ind Med. 2005 Jul; 48(1):63-77. PMID: 15940722.
      View in: PubMed
    30. Lahiri DK, Chen D, Lahiri P, Rogers JT, Greig NH, Bondy S. Melatonin, metals, and gene expression: implications in aging and neurodegenerative disorders. Ann N Y Acad Sci. 2004 Dec; 1035:216-30. PMID: 15681810.
      View in: PubMed
    31. Bondy S, Lahiri DK, Perreau VM, Sharman KZ, Campbell A, Zhou J, Sharman EH. Retardation of brain aging by chronic treatment with melatonin. Ann N Y Acad Sci. 2004 Dec; 1035:197-215. PMID: 15681809.
      View in: PubMed
    32. Lahiri DK, Ge YW, Sharman EH, Bondy S. Age-related changes in serum melatonin in mice: higher levels of combined melatonin and 6-hydroxymelatonin sulfate in the cerebral cortex than serum, heart, liver and kidney tissues. J Pineal Res. 2004 May; 36(4):217-23. PMID: 15066045.
      View in: PubMed
    33. Lahiri DK, Chen D, Ge YW, Bondy S, Sharman EH. Dietary supplementation with melatonin reduces levels of amyloid beta-peptides in the murine cerebral cortex. J Pineal Res. 2004 May; 36(4):224-31. PMID: 15066046.
      View in: PubMed
    34. Sharman EH, Sharman KG, Ge YW, Lahiri DK, Bondy S. Age-related changes in murine CNS mRNA gene expression are modulated by dietary melatonin. J Pineal Res. 2004 Apr; 36(3):165-70. PMID: 15009506.
      View in: PubMed
    35. HaMai D, Bondy S. Oxidative basis of manganese neurotoxicity. Ann N Y Acad Sci. 2004 Mar; 1012:129-41. PMID: 15105260.
      View in: PubMed
    36. HaMai D, Bondy S. Pro- or anti-oxidant manganese: a suggested mechanism for reconciliation. Neurochem Int. 2004 Mar; 44(4):223-9. PMID: 14602085.
      View in: PubMed
    37. Becaria A, Bondy S, Campbell A. Aluminum and copper interact in the promotion of oxidative but not inflammatory events: implications for Alzheimer's disease. J Alzheimers Dis. 2003 Feb; 5(1):31-8. PMID: 12590164.
      View in: PubMed
    38. Sharman KG, Sharman EH, Yang E, Bondy S. Dietary melatonin selectively reverses age-related changes in cortical cytokine mRNA levels, and their responses to an inflammatory stimulus. Neurobiol Aging. 2002 Jul-Aug; 23(4):633-8. PMID: 12009512.
      View in: PubMed
    39. Campbell A, Yang EY, Tsai-Turton M, Bondy S. Pro-inflammatory effects of aluminum in human glioblastoma cells. Brain Res. 2002 Apr 12; 933(1):60-5. PMID: 11929636.
      View in: PubMed
    40. Bondy S, Yang YE, Walsh TJ, Gie YW, Lahiri DK. Dietary modulation of age-related changes in cerebral pro-oxidant status. Neurochem Int. 2002 Feb; 40(2):123-30. PMID: 11738478.
      View in: PubMed
    41. Bondy S, Ali SF, Kleinman MT. Exposure of mice to tobacco smoke attenuates the toxic effect of methamphetamine on dopamine systems. Toxicol Lett. 2000 Dec 20; 118(1-2):43-6. PMID: 11137307.
      View in: PubMed
    42. Bondy S, Ali SF, Guo-Ross S. Aluminum but not iron treatment induces pro-oxidant events in the rat brain. Mol Chem Neuropathol. 1998 Jun-Aug; 34(2-3):219-32. PMID: 10327419.
      View in: PubMed
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