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First-in-human trial of engineered NK cells in lung cancer refractory to immune checkpoint inhibitors. JCI Insight. 2025 Feb 04.
Villalona-Calero MA, Tian L, Li X, Palmer JM, Aceves C, Meisen H, Cortez C, Synold TW, Egelston C, VanDeusen J, Bruno I, Zhang L, Romeu-Bonilla E, Butt O, Forman SJ, Caligiuri MA, Yu J. PMID: 39903538.
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PubMed Mentions: Fields:
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Atezolizumab combined with immunogenic salvage chemoimmunotherapy in patients with transformed diffuse large B-cell lymphoma. Haematologica. 2025 Jan 01; 110(1):142-152.
Othman T, Frankel P, Allen P, Popplewell LL, Shouse G, Siddiqi T, Danilov AV, Ruel N, Daniels S, Peters L, Khoo S, Rosen ST, Sharon E, Villalona-Calero M, Ruel C, Tuscano J, Herrera AF. PMID: 39021209; PMCID: PMC11694104.
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PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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The Impact of Medicaid Expansion on Stage at Diagnosis of Melanoma Patients: A Retrospective Study. Cancers (Basel). 2024 Dec 28; 17(1).
Muddasani R, Wu HT, Win S, Amini A, Modi B, Salgia R, Trisal V, Wang EW, Villalona-Calero MA, Chan A, Xing Y. PMID: 39796689; PMCID: PMC11719024.
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PubMed Mentions:
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Phase II study of MEK inhibitor trametinib alone and in combination with AKT inhibitor GSK2141795/uprosertib in patients with metastatic triple negative breast cancer. Breast Cancer Res Treat. 2025 Feb; 210(1):179-189.
Prasath V, Boutrid H, Wesolowski R, Abdel-Rasoul M, Timmers C, Lustberg M, Layman RM, Macrae E, Mrozek E, Shapiro C, Glover K, Vater M, Budd GT, Harris L, Isaacs C, Dees C, Perou CM, Johnson GL, Poklepovic A, Chen H, Villalona-Calero M, Carson W, Stover DG, Ramaswamy B. PMID: 39644403.
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PubMed Mentions: Fields:
Translation:
CTClinical Trials
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First-in-human study of AMG 193, an MTA-cooperative PRMT5 inhibitor, in patients with MTAP-deleted solid tumors: results from phase I dose exploration. Ann Oncol. 2024 Dec; 35(12):1138-1147.
Rodon J, Prenen H, Sacher A, Villalona-Calero M, Penel N, El Helali A, Rottey S, Yamamoto N, Ghiringhelli F, Goebeler ME, Doi T, Postel-Vinay S, Lin CC, Liu C, Chuang CH, Keyvanjah K, Eggert T, O'Neil BH. PMID: 39293516.
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PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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Preclinical Evaluation of Off-The-Shelf PD-L1+ Human Natural Killer Cells Secreting IL15 to Treat Non-Small Cell Lung Cancer. Cancer Immunol Res. 2024 Jun 04; 12(6):731-743.
Lu T, Ma R, Mansour AG, Bustillos C, Li Z, Li Z, Ma S, Teng KY, Chen H, Zhang J, Villalona-Calero MA, Caligiuri MA, Yu J. PMID: 38572955; PMCID: PMC11218741.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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A novel HLA-DQB2::MET gene fusion variant in lung adenocarcinoma with prolonged response to tepotinib: a case report. Transl Lung Cancer Res. 2024 May 31; 13(5):1163-1168.
Dias E Silva D, Mambetsariev I, Fricke J, Babikian R, Dingal ST, Mazdisnian F, Badie B, Arvanitis L, Afkhami M, Villalona-Calero M, Salgia R. PMID: 38854944; PMCID: PMC11157375.
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PubMed Mentions:
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A phase II study of bevacizumab and temsirolimus in advanced extra-pancreatic neuroendocrine tumors. Endocr Relat Cancer. 2023 Nov 01; 30(11).
Abuzakhm SM, Sukrithan V, Fruth B, Qin R, Strosberg J, Hobday TJ, Semrad T, Reidy-Lagunes D, Kindler HL, Kim GP, Knox JJ, Kaubisch A, Villalona-Calero M, Chen H, Erlichman C, Shah MH. PMID: 37702588; PMCID: PMC10585708.
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PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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Targeted Therapies in Early-Stage Resectable Non-Small-Cell Lung Cancer: New Kids on the Block. JCO Precis Oncol. 2023 Sep; 7:e2200445.
Liu J, Amini A, Govindarajan A, Abuali T, Mambetsariev I, Massarelli E, Villaflor V, Villalona-Calero M, West H, Williams T, Salgia R. PMID: 37656950.
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PubMed Mentions:
3 Fields:
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Stereotactic Body Radiation Therapy for Oligoprogressive and Oligorecurrent Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2023 Nov; 24(7):651-659.
Ebadi M, Ladbury C, Liu J, Rock A, Onyshchenko M, Villaflor V, Villalona-Calero M, Salgia R, Massarelli E, Lee P, Williams T, Amini A. PMID: 37714807.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Integrating Early-Stage Drug Development with Clinical Networks; Challenges and Opportunities: The City of Hope Developing Experience. J Clin Med. 2023 Jun 15; 12(12).
Villalona-Calero MA, Malhotra J, Chung V, Xing Y, Gray SW, Hampel H, Gruber S, McDonnell K. PMID: 37373756; PMCID: PMC10299326.
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PubMed Mentions:
2
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Order of patient entry and outcomes in phase II clinical trials: A meta-analysis of individual patient data. Contemp Clin Trials. 2023 Feb; 125:107083.
Behrendt CE, Villalona-Calero MA, Newman EM, Frankel PH. PMID: 36638911.
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PubMed Mentions: Fields:
Translation:
Humans
-
Adjunctive PD-1 inhibitor versus standard chemotherapy in recurrent or metastatic nasopharyngeal carcinoma: a systematic review and meta-analysis. Ther Adv Med Oncol. 2022; 14:17588359221137429.
Polintan ET, Canicula SK, Catahay JA, Lo KB, Villalona-Calero M, Loong HH. PMID: 36407786; PMCID: PMC9666866.
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PubMed Mentions:
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Ablative Radiotherapy as a Strategy to Overcome TKI Resistance in EGFR-Mutated NSCLC. Cancers (Basel). 2022 Aug 18; 14(16).
Novak J, Salgia R, West H, Villalona-Calero MA, Sampath S, Williams T, Villaflor V, Massarelli E, Pathak R, Koczywas M, Chau B, Amini A. PMID: 36010982; PMCID: PMC9406789.
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PubMed Mentions:
4
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Pembrolizumab activity in patients with Fanconi anemia repair pathway competent and deficient tumors. Biomark Res. 2022 Jun 03; 10(1):39.
Villalona-Calero MA, Diaz JP, Duan W, Diaz Z, Schroeder ED, Aparo S, Gatcliffe T, Albrecht F, Venkatappa S, Guardiola V, Garrido S, Rubens M, DeZarraga F, Vuong H. PMID: 35658948; PMCID: PMC9164357.
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PubMed Mentions:
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Disparities in Cancer Care and Scientific Knowledge in Hispanic/Latinx People in the United States. JCO Oncol Pract. 2022 May; 18(5):367-369.
Bosserman LD, Duma N, Villalona-Calero M, Lopes G, Cinar P. PMID: 35544649.
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PubMed Mentions: Fields:
Translation:
Humans
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Patterns of Care in Maintenance Therapy in US Patients Undergoing Definitive Chemoradiation for Stage 3 Non-Small Cell Lung Cancer (NSCLC). Am J Clin Oncol. 2022 Feb 01; 45(2):49-54.
Liu J, Bratton E, Yu X, Ladbury C, Wagner J, West H, Massarelli E, Salgia R, Pathak R, Villaflor V, Villalona-Calero M, Amini A. PMID: 34991107.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Clinical Outcomes for Plasma-Based Comprehensive Genomic Profiling Versus Standard-of-Care Tissue Testing in Advanced Non-Small Cell Lung Cancer. Clin Lung Cancer. 2022 01; 23(1):72-81.
Page RD, Drusbosky LM, Dada H, Raymond VM, Daniel DB, Divers SG, Reckamp KL, Villalona-Calero MA, Dix D, Odegaard JI, Lanman RB, Papadimitrakopoulou VA, Leighl NB. PMID: 34782240.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Splicing reprogramming of TRAIL/DISC-components sensitizes lung cancer cells to TRAIL-mediated apoptosis. Cell Death Dis. 2021 Mar 17; 12(4):287.
Voss OH, Arango D, Tossey JC, Villalona Calero MA, Doseff AI. PMID: 33731677; PMCID: PMC7969956.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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MiRNA-200C expression in Fanconi anemia pathway functionally deficient lung cancers. Sci Rep. 2021 Feb 24; 11(1):4420.
Duan W, Tang S, Gao L, Dotts K, Fink A, Kalvala A, Aguila B, Wang QE, Villalona-Calero MA. PMID: 33627769; PMCID: PMC7904768.
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PubMed Mentions: Fields:
Translation:
HumansCells
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The oncogenic potential of a mutant TP53 gene explored in two spontaneous lung cancer mice models. BMC Cancer. 2020 Aug 08; 20(1):738.
Ramelow J, Brooks CD, Gao L, Almiman AA, Williams TM, Villalona-Calero MA, Duan W. PMID: 32770960; PMCID: PMC7414707.
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PubMed Mentions:
6 Fields:
Translation:
Animals
-
Phase I Study of Veliparib on an Intermittent and Continuous Schedule in Combination with Carboplatin in Metastatic Breast Cancer: A Safety and [18F]-Fluorothymidine Positron Emission Tomography Biomarker Study. Oncologist. 2020 Aug; 25(8):e1158-e1169.
Wesolowski R, Stover DG, Lustberg MB, Shoben A, Zhao M, Mrozek E, Layman RM, Macrae E, Duan W, Zhang J, Hall N, Wright CL, Gillespie S, Berger M, Chalmers JJ, Carey A, Balasubramanian P, Miller BL, Amaya P, Andreopoulou E, Sparano J, Shapiro CL, Villalona-Calero MA, Geyer S, Chen A, Grever MR, Knopp MV, Ramaswamy B. PMID: 32452601; PMCID: PMC7418347.
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PubMed Mentions:
7 Fields:
Translation:
HumansCTClinical Trials
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A Phase II Trial of Albumin-Bound Paclitaxel and Gemcitabine in Patients with Newly Diagnosed Stage IV Squamous Cell Lung Cancers. Clin Cancer Res. 2020 Apr 15; 26(8):1796-1802.
Paik PK, Kim RK, Ahn L, Plodkowski AJ, Ni A, Donoghue MTA, Jonsson P, Villalona-Calero M, Ng K, McFarland D, Fiore JJ, Iqbal A, Eng J, Kris MG, Rudin CM. PMID: 31919132; PMCID: PMC7169419.
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PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Clinical Utility of Comprehensive Cell-free DNA Analysis to Identify Genomic Biomarkers in Patients with Newly Diagnosed Metastatic Non-small Cell Lung Cancer. Clin Cancer Res. 2019 Aug 01; 25(15):4691-4700.
Leighl NB, Page RD, Raymond VM, Daniel DB, Divers SG, Reckamp KL, Villalona-Calero MA, Dix D, Odegaard JI, Lanman RB, Papadimitrakopoulou VA. PMID: 30988079.
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PubMed Mentions:
245 Fields:
Translation:
Humans
-
Type of TP53 mutation influences oncogenic potential and spectrum of associated K-ras mutations in lung-specific transgenic mice. Int J Cancer. 2019 Nov 01; 145(9):2418-2426.
Duan W, Gao L, Kalvala A, Aguila B, Brooks C, Mo X, Ding H, Shilo K, Otterson GA, Villalona-Calero MA. PMID: 30873587.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Incidence, Risk Factors, and Effect on Survival of Immune-related Adverse Events in Patients With Non-Small-cell Lung Cancer. Clin Lung Cancer. 2018 Nov; 19(6):e893-e900.
Owen DH, Wei L, Bertino EM, Edd T, Villalona-Calero MA, He K, Shields PG, Carbone DP, Otterson GA. PMID: 30197259; PMCID: PMC7193681.
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PubMed Mentions:
65 Fields:
Translation:
Humans
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Phase II randomized, double-blind, placebo-controlled study of tivantinib in men with asymptomatic or minimally symptomatic metastatic castration-resistant prostate cancer (mCRPC). Invest New Drugs. 2018 Oct; 36(5):919-926.
Monk P, Liu G, Stadler WM, Geyer S, Huang Y, Wright J, Villalona-Calero M, Wade J, Szmulewitz R, Gupta S, Mortazavi A, Dreicer R, Pili R, Dawson N, George S, Garcia JA. PMID: 30083962; PMCID: PMC6153554.
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PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Predicting response to checkpoint inhibitors in melanoma beyond PD-L1 and mutational burden. J Immunother Cancer. 2018 May 09; 6(1):32.
Morrison C, Pabla S, Conroy JM, Nesline MK, Glenn ST, Dressman D, Papanicolau-Sengos A, Burgher B, Andreas J, Giamo V, Qin M, Wang Y, Lenzo FL, Omilian A, Bshara W, Zibelman M, Ghatalia P, Dragnev K, Shirai K, Madden KG, Tafe LJ, Shah N, Kasuganti D, de la Cruz-Merino L, Araujo I, Saenger Y, Bogardus M, Villalona-Calero M, Diaz Z, Day R, Eisenberg M, Anderson SM, Puzanov I, Galluzzi L, Gardner M, Ernstoff MS. PMID: 29743104; PMCID: PMC5944039.
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PubMed Mentions:
75 Fields:
Translation:
Humans
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EML4-ALK Rearrangement and Its Therapeutic Implications in Inflammatory Myofibroblastic Tumors. Oncologist. 2018 Oct; 23(10):1127-1132.
Vargas-Madueno F, Gould E, Valor R, Ngo N, Zhang L, Villalona-Calero MA. PMID: 29739898; PMCID: PMC6263129.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Randomized phase II trial of fulvestrant alone or in combination with bortezomib in hormone receptor-positive metastatic breast cancer resistant to aromatase inhibitors: a New York Cancer Consortium trial. NPJ Breast Cancer. 2016; 2:16037.
Adelson K, Ramaswamy B, Sparano JA, Christos PJ, Wright JJ, Raptis G, Han G, Villalona-Calero M, Ma CX, Hershman D, Baar J, Klein P, Cigler T, Budd GT, Novik Y, Tan AR, Tannenbaum S, Goel A, Levine E, Shapiro CL, Andreopoulou E, Naughton M, Kalinsky K, Waxman S, Germain D. PMID: 28721390; PMCID: PMC5515340.
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PubMed Mentions:
21
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Rad51C-ATXN7 fusion gene expression in colorectal tumors. Mol Cancer. 2016 Jun 13; 15(1):47.
Kalvala A, Gao L, Aguila B, Dotts K, Rahman M, Nana-Sinkam SP, Zhou X, Wang QE, Amann J, Otterson GA, Villalona-Calero MA, Duan W. PMID: 27296891; PMCID: PMC4906819.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Randomized Phase 2 Trial of the Oncolytic Virus Pelareorep (Reolysin) in Upfront Treatment of Metastatic Pancreatic Adenocarcinoma. Mol Ther. 2016 Jun; 24(6):1150-1158.
Noonan AM, Farren MR, Geyer SM, Huang Y, Tahiri S, Ahn D, Mikhail S, Ciombor KK, Pant S, Aparo S, Sexton J, Marshall JL, Mace TA, Wu CS, El-Rayes B, Timmers CD, Zwiebel J, Lesinski GB, Villalona-Calero MA, Bekaii-Saab TS. PMID: 27039845; PMCID: PMC4923331.
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PubMed Mentions:
72 Fields:
Translation:
HumansCellsCTClinical Trials
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Veliparib Alone or in Combination with Mitomycin C in Patients with Solid Tumors With Functional Deficiency in Homologous Recombination Repair. J Natl Cancer Inst. 2016 Jul; 108(7).
Villalona-Calero MA, Duan W, Zhao W, Shilo K, Schaaf LJ, Thurmond J, Westman JA, Marshall J, Xiaobai L, Ji J, Rose J, Lustberg M, Bekaii-Saab T, Chen A, Timmers C. PMID: 26848151; PMCID: PMC4948564.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Clinical Cancer Advances 2016: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology. J Clin Oncol. 2016 Mar 20; 34(9):987-1011.
Dizon DS, Krilov L, Cohen E, Gangadhar T, Ganz PA, Hensing TA, Hunger S, Krishnamurthi SS, Lassman AB, Markham MJ, Mayer E, Neuss M, Pal SK, Richardson LC, Schilsky R, Schwartz GK, Spriggs DR, Villalona-Calero MA, Villani G, Masters G. PMID: 26846975; PMCID: PMC5075244.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Systemic Immune Activity Predicts Overall Survival in Treatment-Naïve Patients with Metastatic Pancreatic Cancer. Clin Cancer Res. 2016 May 15; 22(10):2565-74.
Farren MR, Mace TA, Geyer S, Mikhail S, Wu C, Ciombor K, Tahiri S, Ahn D, Noonan AM, Villalona-Calero M, Bekaii-Saab T, Lesinski GB. PMID: 26719427; PMCID: PMC4867263.
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PubMed Mentions:
51 Fields:
Translation:
HumansCellsCTClinical Trials
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Oncolytic reovirus in combination with chemotherapy in metastatic or recurrent non-small cell lung cancer patients with KRAS-activated tumors. Cancer. 2016 Mar 15; 122(6):875-83.
Villalona-Calero MA, Lam E, Otterson GA, Zhao W, Timmons M, Subramaniam D, Hade EM, Gill GM, Coffey M, Selvaggi G, Bertino E, Chao B, Knopp MV. PMID: 26709987; PMCID: PMC5068485.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Biomodulation of capecitabine by paclitaxel and carboplatin in advanced solid tumors and adenocarcinoma of unknown primary. Cancer Chemother Pharmacol. 2015 Nov; 76(5):1005-12.
Mikhail S, Lustberg MB, Ruppert AS, Mortazavi A, Monk P, Kleiber B, Villalona-Calero M, Bekaii-Saab T. PMID: 26416564.
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PubMed Mentions:
2 Fields:
Translation:
HumansCellsCTClinical Trials
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Results of an abbreviated phase-II study with the Akt Inhibitor MK-2206 in Patients with Advanced Biliary Cancer. Sci Rep. 2015 Jul 10; 5:12122.
Ahn DH, Li J, Wei L, Doyle A, Marshall JL, Schaaf LJ, Phelps MA, Villalona-Calero MA, Bekaii-Saab T. PMID: 26161813; PMCID: PMC4894406.
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PubMed Mentions:
40 Fields:
Translation:
HumansCTClinical Trials
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Stromal Caveolin-1 Is Associated With Response and Survival in a Phase II Trial of nab-Paclitaxel With Carboplatin for Advanced NSCLC Patients. Clin Lung Cancer. 2015 Nov; 16(6):466-74.
Bertino EM, Williams TM, Nana-Sinkam SP, Shilo K, Chatterjee M, Mo X, Rahmani M, Phillips GS, Villalona-Calero MA, Otterson GA. PMID: 26123189; PMCID: PMC5076571.
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PubMed Mentions:
31 Fields:
Translation:
HumansCellsCTClinical Trials
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Overexpression of Rad51C splice variants in colorectal tumors. Oncotarget. 2015 Apr 20; 6(11):8777-87.
Kalvala A, Gao L, Aguila B, Reese T, Otterson GA, Villalona-Calero MA, Duan W. PMID: 25669972; PMCID: PMC4496183.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Randomized Trial of Oral Cyclophosphamide and Veliparib in High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers, or BRCA-Mutant Ovarian Cancer. Clin Cancer Res. 2015 Apr 01; 21(7):1574-82.
Kummar S, Oza AM, Fleming GF, Sullivan DM, Gandara DR, Naughton MJ, Villalona-Calero MA, Morgan RJ, Szabo PM, Youn A, Chen AP, Ji J, Allen DE, Lih CJ, Mehaffey MG, Walsh WD, McGregor PM, Steinberg SM, Williams PM, Kinders RJ, Conley BA, Simon RM, Doroshow JH. PMID: 25589624; PMCID: PMC4383665.
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PubMed Mentions:
58 Fields:
Translation:
HumansCTClinical Trials
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Fanconi anemia repair pathway dysfunction, a potential therapeutic target in lung cancer. Front Oncol. 2014; 4:368.
Duan W, Gao L, Aguila B, Kalvala A, Otterson GA, Villalona-Calero MA. PMID: 25566506; PMCID: PMC4271581.
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PubMed Mentions:
23
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A multicenter phase I study of pazopanib in combination with paclitaxel in first-line treatment of patients with advanced solid tumors. Mol Cancer Ther. 2015 Feb; 14(2):461-9.
Kendra KL, Plummer R, Salgia R, O'Brien ME, Paul EM, Suttle AB, Compton N, Xu CF, Ottesen LH, Villalona-Calero MA. PMID: 25504632.
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PubMed Mentions:
16 Fields:
Translation:
HumansCTClinical Trials
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Increased NQO1 but not c-MET and survivin expression in non-small cell lung carcinoma with KRAS mutations. Int J Environ Res Public Health. 2014 Sep 12; 11(9):9491-502.
Yilmaz A, Mohamed N, Patterson KA, Tang Y, Shilo K, Villalona-Calero MA, Davis ME, Zhou X, Frankel W, Otterson GA, Beall HD, Zhao W. PMID: 25222473; PMCID: PMC4199031.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Clinical and metabolic parameters in non-small cell lung carcinoma and colorectal cancer patients with and without KRAS mutations. Int J Environ Res Public Health. 2014 Aug 25; 11(9):8645-60.
Yilmaz A, Mohamed N, Patterson KA, Tang Y, Shilo K, Villalona-Calero MA, Davis ME, Zhou XP, Frankel W, Otterson GA, Zhao W. PMID: 25158139; PMCID: PMC4198984.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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From single-gene to multiplex analysis in lung cancer, challenges and accomplishments: a review of a single institution's experience. Lung Cancer Manag. 2014 Aug 01; 4(3):315-324.
Zhao W, Damodaran S, Villalona-Calero MA. PMID: 25580159; PMCID: PMC4286371.
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PubMed Mentions:
1
-
FANCD2 is a potential therapeutic target and biomarker in alveolar rhabdomyosarcoma harboring the PAX3-FOXO1 fusion gene. Clin Cancer Res. 2014 Jul 15; 20(14):3884-95.
Singh M, Leasure JM, Chronowski C, Geier B, Bondra K, Duan W, Hensley LA, Villalona-Calero M, Li N, Vergis AM, Kurmasheva RT, Shen C, Woods G, Sebastian N, Fabian D, Kaplon R, Hammond S, Palanichamy K, Chakravarti A, Houghton PJ. PMID: 24787670; PMCID: PMC4102646.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Erlotinib in African Americans with advanced non-small cell lung cancer: a prospective randomized study with genetic and pharmacokinetic analyses. Clin Pharmacol Ther. 2014 Aug; 96(2):182-91.
Phelps MA, Stinchcombe TE, Blachly JS, Zhao W, Schaaf LJ, Starrett SL, Wei L, Poi M, Wang D, Papp A, Aimiuwu J, Gao Y, Li J, Otterson GA, Hicks WJ, Socinski MA, Villalona-Calero MA. PMID: 24781527; PMCID: PMC4180036.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma. J Clin Invest. 2014 Apr; 124(4):1582-6.
Imielinski M, Greulich H, Kaplan B, Araujo L, Amann J, Horn L, Schiller J, Villalona-Calero MA, Meyerson M, Carbone DP. PMID: 24569458; PMCID: PMC3973082.
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PubMed Mentions:
64 Fields:
Translation:
Humans
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CALGB 30704 (Alliance): A randomized phase II study to assess the efficacy of pemetrexed or sunitinib or pemetrexed plus sunitinib in the second-line treatment of advanced non-small-cell lung cancer. J Thorac Oncol. 2014 Feb; 9(2):214-21.
Heist RS, Wang X, Hodgson L, Otterson GA, Stinchcombe TE, Gandhi L, Villalona-Calero MA, Watson P, Vokes EE, Socinski MA, Alliance for Clinical Trials in Oncology. PMID: 24419419; PMCID: PMC4284815.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCTClinical Trials
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Y-chromosome status identification suggests a recipient origin of posttransplant non-small cell lung carcinomas: chromogenic in situ hybridization analysis. Hum Pathol. 2014 May; 45(5):1065-70.
Chen W, Brodsky SV, Zhao W, Otterson GA, Villalona-Calero M, Satoskar AA, Hasan A, Pelletier R, Ivanov I, Ross P, Nadasdy T, Shilo K. PMID: 24746212; PMCID: PMC4271837.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Race and ethnicity in cancer therapy: what have we learned? Clin Pharmacol Ther. 2014 Apr; 95(4):403-12.
Grenade C, Phelps MA, Villalona-Calero MA. PMID: 24419564.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Cellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors. Diagn Pathol. 2013 Dec 10; 8:201.
Shilo K, Wu X, Sharma S, Welliver M, Duan W, Villalona-Calero M, Fukuoka J, Sif S, Baiocchi R, Hitchcock CL, Zhao W, Otterson GA. PMID: 24326178; PMCID: PMC3933389.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Disrupting cytokine signaling in pancreatic cancer: a phase I/II study of etanercept in combination with gemcitabine in patients with advanced disease. Pancreas. 2013 Jul; 42(5):813-8.
Wu C, Fernandez SA, Criswell T, Chidiac TA, Guttridge D, Villalona-Calero M, Bekaii-Saab TS. PMID: 23429495; PMCID: PMC3664263.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCellsCTClinical Trials
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Case of sorafenib-induced thyroid storm. J Clin Oncol. 2013 Jun 01; 31(16):e262-4.
Haraldsdottir S, Li Q, Villalona-Calero MA, Olencki TE, Kendra K, Ing SW. PMID: 23610115.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
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Inhibition of Ras-Effector Interaction by Cyclic Peptides. Medchemcomm. 2013 Feb 01; 4(2):378-382.
Wu X, Upadhyaya P, Villalona-Calero MA, Briesewitz R, Pei D. PMID: 23585920; PMCID: PMC3621770.
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PubMed Mentions:
28
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In vivo quantification of active decitabine-triphosphate metabolite: a novel pharmacoanalytical endpoint for optimization of hypomethylating therapy in acute myeloid leukemia. AAPS J. 2013 Jan; 15(1):242-9.
Wang H, Chen P, Wang J, Santhanam R, Aimiuwu J, Saradhi UV, Liu Z, Schwind S, Mims A, Byrd JC, Grever MR, Villalona-Calero MA, Klisovic R, Walker A, Garzon R, Blum W, Chan KK, Marcucci G. PMID: 23180159; PMCID: PMC3535094.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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RET fusion genes in non-small-cell lung cancer. J Clin Oncol. 2012 Dec 10; 30(35):4439-41.
Chao BH, Briesewitz R, Villalona-Calero MA. PMID: 23150705.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
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A phase II study of modulated-capecitabine and docetaxel in chemonaive patients with advanced non-small cell lung cancer (NSCLC). Lung Cancer. 2013 Jan; 79(1):27-32.
Bertino EM, Bekaii-Saab T, Fernandez S, Diasio RB, Karim NA, Otterson GA, Villalona-Calero MA. PMID: 23079156; PMCID: PMC3549571.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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Assessment of FANCD2 nuclear foci formation in paraffin-embedded tumors: a potential patient-enrichment strategy for treatment with DNA interstrand crosslinking agents. Transl Res. 2013 Mar; 161(3):156-64.
Duan W, Gao L, Zhao W, Leon M, Sadee W, Webb A, Resnick K, Wu X, Ramaswamy B, Cohn DE, Shapiro C, Andreassen PR, Otterson GA, Villalona-Calero MA. PMID: 23063585; PMCID: PMC3755957.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Phase I study of 5-aza-2'-deoxycytidine in combination with valproic acid in non-small-cell lung cancer. Cancer Chemother Pharmacol. 2013 Jan; 71(1):115-21.
Chu BF, Karpenko MJ, Liu Z, Aimiuwu J, Villalona-Calero MA, Chan KK, Grever MR, Otterson GA. PMID: 23053268.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCTClinical Trials
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Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB 30406 trial. J Clin Oncol. 2012 Jun 10; 30(17):2063-9.
Jänne PA, Wang X, Socinski MA, Crawford J, Stinchcombe TE, Gu L, Capelletti M, Edelman MJ, Villalona-Calero MA, Kratzke R, Vokes EE, Miller VA. PMID: 22547605; PMCID: PMC3397694.
View in:
PubMed Mentions:
119 Fields:
Translation:
HumansCTClinical Trials
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Altered p16(INK4) and RB1 Expressions Are Associated with Poor Prognosis in Patients with Nonsmall Cell Lung Cancer. J Oncol. 2012; 2012:957437.
Zhao W, Huang CC, Otterson GA, Leon ME, Tang Y, Shilo K, Villalona MA. PMID: 22619677; PMCID: PMC3350860.
View in:
PubMed Mentions:
16
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HER2/neu may not be an interesting target in biliary cancers: results of an early phase II study with lapatinib. Oncology. 2012; 82(3):175-9.
Peck J, Wei L, Zalupski M, O'Neil B, Villalona Calero M, Bekaii-Saab T. PMID: 22433475.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCTClinical Trials
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Bortezomib for patients with advanced-stage bronchioloalveolar carcinoma: a California Cancer Consortium Phase II study (NCI 7003). J Thorac Oncol. 2011 Oct; 6(10):1741-5.
Ramalingam SS, Davies AM, Longmate J, Edelman MJ, Lara PN, Vokes EE, Villalona-Calero M, Gitlitz B, Reckamp K, Salgia R, Wright JJ, Belani CP, Gandara DR. PMID: 21716143; PMCID: PMC3220078.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Phase I dose escalation study of KOS-1584, a novel epothilone, in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2012 Feb; 69(2):523-31.
Lam ET, Goel S, Schaaf LJ, Cropp GF, Hannah AL, Zhou Y, McCracken B, Haley BI, Johnson RG, Mani S, Villalona-Calero MA. PMID: 21874318; PMCID: PMC3865603.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCellsCTClinical Trials
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A phase 1 study of KOS-862 (Epothilone D) co-administered with carboplatin (Paraplatin®) in patients with advanced solid tumors. Invest New Drugs. 2012 Aug; 30(4):1676-83.
Monk JP, Villalona-Calero M, Larkin J, Otterson G, Spriggs DS, Hannah AL, Cropp GF, Johnson RG, Hensley ML. PMID: 21826439; PMCID: PMC5098268.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Creating diverse target-binding surfaces on FKBP12: synthesis and evaluation of a rapamycin analogue library. ACS Comb Sci. 2011 Sep 12; 13(5):486-95.
Wu X, Wang L, Han Y, Regan N, Li PK, Villalona MA, Hu X, Briesewitz R, Pei D. PMID: 21766878; PMCID: PMC3171579.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
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Risk factors for tumor lysis syndrome in patients with chronic lymphocytic leukemia treated with the cyclin-dependent kinase inhibitor, flavopiridol. Leukemia. 2011 Sep; 25(9):1444-51.
Blum KA, Ruppert AS, Woyach JA, Jones JA, Andritsos L, Flynn JM, Rovin B, Villalona-Calero M, Ji J, Phelps M, Johnson AJ, Grever MR, Byrd JC. PMID: 21606960; PMCID: PMC3162125.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
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Multi-institutional phase II study of selumetinib in patients with metastatic biliary cancers. J Clin Oncol. 2011 Jun 10; 29(17):2357-63.
Bekaii-Saab T, Phelps MA, Li X, Saji M, Goff L, Kauh JS, O'Neil BH, Balsom S, Balint C, Liersemann R, Vasko VV, Bloomston M, Marsh W, Doyle LA, Ellison G, Grever M, Ringel MD, Villalona-Calero MA. PMID: 21519026; PMCID: PMC3107751.
View in:
PubMed Mentions:
137 Fields:
Translation:
HumansCellsCTClinical Trials
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Preoperative bevacizumab in combination with paclitaxel and carboplatin in surgically resectable non-small cell lung cancer. Ann Thorac Surg. 2011 Feb; 91(2):640.
Bertino E, Villalona-Calero MA, Ross P, Grever M, Otterson GA. PMID: 21256341; PMCID: PMC4271821.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Phase II trials of single-agent anti-VEGF therapy for patients with chronic lymphocytic leukemia. Leuk Lymphoma. 2010 Dec; 51(12):2222-9.
Shanafelt T, Zent C, Byrd J, Erlichman C, Laplant B, Ghosh A, Call T, Villalona-Calero M, Jelinek D, Bowen D, Laumann K, Wu W, Hanson C, Kay N. PMID: 21054149; PMCID: PMC3928074.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCTClinical Trials
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The search for an optimal DNA, RNA, and protein detection by in situ hybridization, immunohistochemistry, and solution-based methods. Methods. 2010 Dec; 52(4):281-6.
Yan F, Wu X, Crawford M, Duan W, Wilding EE, Gao L, Nana-Sinkam SP, Villalona-Calero MA, Baiocchi RA, Otterson GA. PMID: 20888418; PMCID: PMC3375896.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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MicroRNA-34a is an important component of PRIMA-1-induced apoptotic network in human lung cancer cells. Int J Cancer. 2010 Jul 15; 127(2):313-20.
Duan W, Gao L, Wu X, Wang L, Nana-Sinkam SP, Otterson GA, Villalona-Calero MA. PMID: 19921694; PMCID: PMC4153870.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Phase II randomized study of two regimens of sequentially administered mitomycin C and irinotecan in patients with unresectable esophageal and gastroesophageal adenocarcinoma. J Thorac Oncol. 2010 May; 5(5):713-8.
Lustberg MB, Bekaii-Saab T, Young D, Otterson G, Burak W, Abbas A, McCracken-Bussa B, Lustberg ME, Villalona-Calero MA. PMID: 20354452; PMCID: PMC3641556.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Phase I/II study of inhaled doxorubicin combined with platinum-based therapy for advanced non-small cell lung cancer. Clin Cancer Res. 2010 Apr 15; 16(8):2466-73.
Otterson GA, Villalona-Calero MA, Hicks W, Pan X, Ellerton JA, Gettinger SN, Murren JR. PMID: 20371682; PMCID: PMC4262532.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCTClinical Trials
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Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer. J Clin Oncol. 2010 May 10; 28(14):2323-30.
Lam ET, Ringel MD, Kloos RT, Prior TW, Knopp MV, Liang J, Sammet S, Hall NC, Wakely PE, Vasko VV, Saji M, Snyder PJ, Wei L, Arbogast D, Collamore M, Wright JJ, Moley JF, Villalona-Calero MA, Shah MH. PMID: 20368568; PMCID: PMC2881718.
View in:
PubMed Mentions:
132 Fields:
Translation:
HumansCTClinical Trials
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Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7473-8.
Blum W, Garzon R, Klisovic RB, Schwind S, Walker A, Geyer S, Liu S, Havelange V, Becker H, Schaaf L, Mickle J, Devine H, Kefauver C, Devine SM, Chan KK, Heerema NA, Bloomfield CD, Grever MR, Byrd JC, Villalona-Calero M, Croce CM, Marcucci G. PMID: 20368434; PMCID: PMC2867720.
View in:
PubMed Mentions:
208 Fields:
Translation:
HumansCellsCTClinical Trials
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Malignant thymoma with immunodeficiency (Good syndrome) associated with mucormycosis. Am J Clin Oncol. 2010 Feb; 33(1):109.
Hamadani M, Awan F, Villalona-Calero MA. PMID: 20139744.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Phase I trial of non-cytotoxic suramin as a modulator of docetaxel and gemcitabine therapy in previously treated patients with non-small cell lung cancer. Cancer Chemother Pharmacol. 2010 Nov; 66(6):1019-29.
Lam ET, Au JL, Otterson GA, Guillaume Wientjes M, Chen L, Shen T, Wei Y, Li X, Bekaii-Saab T, Murgo AJ, Jensen RR, Grever M, Villalona-Calero MA. PMID: 20107799; PMCID: PMC2919610.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
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An epigenetic mechanism for capecitabine resistance in mesothelioma. Biochem Biophys Res Commun. 2010 Jan 15; 391(3):1465-70.
Kosuri KV, Wu X, Wang L, Villalona-Calero MA, Otterson GA. PMID: 20035722; PMCID: PMC2860267.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Phase II study of flavopiridol in relapsed chronic lymphocytic leukemia demonstrating high response rates in genetically high-risk disease. J Clin Oncol. 2009 Dec 10; 27(35):6012-8.
Lin TS, Ruppert AS, Johnson AJ, Fischer B, Heerema NA, Andritsos LA, Blum KA, Flynn JM, Jones JA, Hu W, Moran ME, Mitchell SM, Smith LL, Wagner AJ, Raymond CA, Schaaf LJ, Phelps MA, Villalona-Calero MA, Grever MR, Byrd JC. PMID: 19826119; PMCID: PMC2793044.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansCellsCTClinical Trials
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A multi-institutional phase II study of the efficacy and tolerability of lapatinib in patients with advanced hepatocellular carcinomas. Clin Cancer Res. 2009 Sep 15; 15(18):5895-901.
Bekaii-Saab T, Markowitz J, Prescott N, Sadee W, Heerema N, Wei L, Dai Z, Papp A, Campbell A, Culler K, Balint C, O'Neil B, Lee RM, Zalupski M, Dancey J, Chen H, Grever M, Eng C, Villalona-Calero M. PMID: 19737952; PMCID: PMC2774354.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCTClinical Trials
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A phase I dose escalation study of a pharmacobiologically based scheduling of capecitabine and mitomycin C in patients with gastrointestinal malignancies. Cancer Chemother Pharmacol. 2010 Apr; 65(5):863-9.
Bekaii-Saab T, Hill M, Campbell A, Kosuri K, Thomas J, Villalona-Calero M. PMID: 19657639; PMCID: PMC4261191.
View in:
PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
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Expression of a mutant p53 results in an age-related demographic shift in spontaneous lung tumor formation in transgenic mice. PLoS One. 2009; 4(5):e5563.
Duan W, Gao L, Wu X, Hade EM, Gao JX, Ding H, Barsky SH, Otterson GA, Villalona-Calero MA. PMID: 19440353; PMCID: PMC2680060.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301. J Clin Oncol. 2009 Apr 10; 27(11):1800-5.
Miller AA, Murry DJ, Owzar K, Hollis DR, Kennedy EB, Abou-Alfa G, Desai A, Hwang J, Villalona-Calero MA, Dees EC, Lewis LD, Fakih MG, Edelman MJ, Millard F, Frank RC, Hohl RJ, Ratain MJ. PMID: 19255312; PMCID: PMC2668705.
View in:
PubMed Mentions:
71 Fields:
Translation:
HumansCTClinical Trials
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Lack of therapeutic effect of the histone deacetylase inhibitor vorinostat in patients with metastatic radioiodine-refractory thyroid carcinoma. J Clin Endocrinol Metab. 2009 Jan; 94(1):164-70.
Woyach JA, Kloos RT, Ringel MD, Arbogast D, Collamore M, Zwiebel JA, Grever M, Villalona-Calero M, Shah MH. PMID: 18854394; PMCID: PMC2630867.
View in:
PubMed Mentions:
69 Fields:
Translation:
HumansCTClinical Trials
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Phase I and pharmacokinetic study of mitomycin C and celecoxib as potential modulators of tumor resistance to irinotecan in patients with solid malignancies. Cancer Chemother Pharmacol. 2009 May; 63(6):1073-82.
Xu Y, Kolesar JM, Schaaf LJ, Drengler R, Duan W, Otterson G, Shapiro C, Kuhn J, Villalona-Calero MA. PMID: 18795290; PMCID: PMC3933356.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Noncytotoxic suramin as a chemosensitizer in patients with advanced non-small-cell lung cancer: a phase II study. Ann Oncol. 2008 Nov; 19(11):1903-9.
Villalona-Calero MA, Otterson GA, Wientjes MG, Weber F, Bekaii-Saab T, Young D, Murgo AJ, Jensen R, Yeh TK, Wei Y, Zhang Y, Eng C, Grever M, Au JL. PMID: 18632723; PMCID: PMC2733080.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCTClinical Trials
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Phase II study of sequentially administered low-dose mitomycin-C (MMC) and irinotecan (CPT-11) in women with metastatic breast cancer (MBC). Ann Oncol. 2008 Aug; 19(8):1417-1422.
Mrozek E, Kolesar J, Young D, Allen J, Villalona-Calero M, Shapiro CL. PMID: 18407955.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCellsCTClinical Trials
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Lung specific expression of a human mutant p53 affects cell proliferation in transgenic mice. Transgenic Res. 2008 Jun; 17(3):355-66.
Duan W, Gao L, Jin D, Otterson GA, Villalona-Calero MA. PMID: 17968669.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
-
Phase I and pharmacokinetic study of erlotinib for solid tumors in patients with hepatic or renal dysfunction: CALGB 60101. J Clin Oncol. 2007 Jul 20; 25(21):3055-60.
Miller AA, Murry DJ, Owzar K, Hollis DR, Lewis LD, Kindler HL, Marshall JL, Villalona-Calero MA, Edelman MJ, Hohl RJ, Lichtman SM, Ratain MJ. PMID: 17634483.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCTClinical Trials
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Phase I study of inhaled Doxorubicin for patients with metastatic tumors to the lungs. Clin Cancer Res. 2007 Feb 15; 13(4):1246-52.
Otterson GA, Villalona-Calero MA, Sharma S, Kris MG, Imondi A, Gerber M, White DA, Ratain MJ, Schiller JH, Sandler A, Kraut M, Mani S, Murren JR. PMID: 17317836.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCTClinical Trials
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Incorporation of photodynamic therapy as an induction modality in non-small cell lung cancer. Lasers Surg Med. 2006 Dec; 38(10):881-9.
Ross P, Grecula J, Bekaii-Saab T, Villalona-Calero M, Otterson G, Magro C. PMID: 17115382.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells. Exp Cell Res. 2006 Oct 15; 312(17):3370-8.
Duan W, Gao L, Wu X, Zhang Y, Otterson GA, Villalona-Calero MA. PMID: 16934800.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Phase II study of weekly docetaxel and capecitabine in patients with metastatic breast cancer. Clin Breast Cancer. 2006 Jun; 7(2):141-5.
Mrozek E, Ramaswamy B, Young D, Rhoades CA, Kendra K, Allen J, Moore T, Hauger M, Watson H, Merriman N, Nadella P, Villalona-Calero M, Shapiro CL. PMID: 16800973.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Nontoxic suramin as a chemosensitizer in patients: dosing nomogram development. Pharm Res. 2006 Jun; 23(6):1265-74.
Chen D, Song SH, Wientjes MG, Yeh TK, Zhao L, Villalona-Calero M, Otterson GA, Jensen R, Grever M, Murgo AJ, Au JL. PMID: 16715360.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Thalidomide and celecoxib as potential modulators of irinotecan's activity in cancer patients. Cancer Chemother Pharmacol. 2007 Jan; 59(1):23-33.
Villalona-Calero M, Schaaf L, Phillips G, Otterson G, Panico K, Duan W, Kleiber B, Shah M, Young D, Wu WH, Kuhn J. PMID: 16685529.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Assessment of tumor necrosis factor alpha blockade as an intervention to improve tolerability of dose-intensive chemotherapy in cancer patients. J Clin Oncol. 2006 Apr 20; 24(12):1852-9.
Monk JP, Phillips G, Waite R, Kuhn J, Schaaf LJ, Otterson GA, Guttridge D, Rhoades C, Shah M, Criswell T, Caligiuri MA, Villalona-Calero MA. PMID: 16622259.
View in:
PubMed Mentions:
74 Fields:
Translation:
Humans
-
Phase I and pharmacokinetic study of pemetrexed administered every 3 weeks to advanced cancer patients with normal and impaired renal function. J Clin Oncol. 2006 Feb 01; 24(4):552-62.
Mita AC, Sweeney CJ, Baker SD, Goetz A, Hammond LA, Patnaik A, Tolcher AW, Villalona-Calero M, Sandler A, Chaudhuri T, Molpus K, Latz JE, Simms L, Chaudhary AK, Johnson RD, Rowinsky EK, Takimoto CH. PMID: 16391300.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCTClinical Trials
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A phase I clinical and pharmacokinetic study of fenretinide combined with paclitaxel and cisplatin for refractory solid tumors. Invest New Drugs. 2005 Dec; 23(6):555-62.
Otterson GA, Lavelle J, Villalona-Calero MA, Shah M, Wei X, Chan KK, Fischer B, Grever M. PMID: 16034523.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCTClinical Trials
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Limitations of single-strand conformation polymorphism analysis as a high-throughput method for the detection of EGFR mutations in the clinical setting. J Clin Oncol. 2005 Aug 20; 23(24):5847-8; author reply 5848-9.
Weber F, Fukino K, Villalona-Calero M, Eng C. PMID: 16110042.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Variability in organ-specific EGFR mutational spectra in tumour epithelium and stroma may be the biological basis for differential responses to tyrosine kinase inhibitors. Br J Cancer. 2005 May 23; 92(10):1922-6.
Weber F, Fukino K, Sawada T, Williams N, Sweet K, Brena RM, Plass C, Caldes T, Mutter GL, Villalona-Calero MA, Eng C. PMID: 15841079; PMCID: PMC2361765.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
-
Preclinical experience with docetaxel in gastrointestinal cancers. Semin Oncol. 2005 Apr; 32(2 Suppl 4):S3-9.
Bekaii-Saab TS, Villalona-Calero MA. PMID: 16015550.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Phase II evaluation of docetaxel-modulated capecitabine in previously treated patients with non-small cell lung cancer. Clin Cancer Res. 2005 Mar 01; 11(5):1870-6.
Kindwall-Keller T, Otterson GA, Young D, Neki A, Criswell T, Nuovo G, Soong R, Diasio R, Villalona-Calero MA. PMID: 15756012.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer. J Natl Cancer Inst. 2004 Nov 17; 96(22):1718-21.
Duan W, Gao L, Druhan LJ, Zhu WG, Morrison C, Otterson GA, Villalona-Calero MA. PMID: 15547185.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
-
A phase I/II study of LY900003, an antisense inhibitor of protein kinase C-alpha, in combination with cisplatin and gemcitabine in patients with advanced non-small cell lung cancer. Clin Cancer Res. 2004 Sep 15; 10(18 Pt 1):6086-93.
Villalona-Calero MA, Ritch P, Figueroa JA, Otterson GA, Belt R, Dow E, George S, Leonardo J, McCachren S, Miller GL, Modiano M, Valdivieso M, Geary R, Oliver JW, Holmlund J. PMID: 15447994.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCTClinical Trials
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A phase II study of oxaliplatin and paclitaxel in patients with advanced non-small-cell lung cancer. Ann Oncol. 2004 Jun; 15(6):915-20.
Winegarden JD, Mauer AM, Otterson GA, Rudin CM, Villalona-Calero MA, Lanzotti VJ, Szeto L, Kasza K, Hoffman PC, Vokes EE, University of Chicago Phase II Network, Ohio State University. PMID: 15151948.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCTClinical Trials
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5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation. J Biol Chem. 2004 Apr 09; 279(15):15161-6.
Zhu WG, Hileman T, Ke Y, Wang P, Lu S, Duan W, Dai Z, Tong T, Villalona-Calero MA, Plass C, Otterson GA. PMID: 14722112.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansCells
-
A phase I and pharmacokinetic study of irinotecan in patients with hepatic or renal dysfunction or with prior pelvic radiation: CALGB 9863. Ann Oncol. 2003 Dec; 14(12):1783-90.
Venook AP, Enders Klein C, Fleming G, Hollis D, Leichman CG, Hohl R, Byrd J, Budman D, Villalona M, Marshall J, Rosner GL, Ramirez J, Kastrissios H, Ratain MJ. PMID: 14630685.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCTClinical Trials
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Phase I study of low-dose suramin as a chemosensitizer in patients with advanced non-small cell lung cancer. Clin Cancer Res. 2003 Aug 15; 9(9):3303-11.
Villalona-Calero MA, Wientjes MG, Otterson GA, Kanter S, Young D, Murgo AJ, Fischer B, DeHoff C, Chen D, Yeh TK, Song S, Grever M, Au JL. PMID: 12960116.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCTClinical Trials
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P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells. Biochem Biophys Res Commun. 2003 Jun 13; 305(4):950-6.
Ding H, Duan W, Zhu WG, Ju R, Srinivasan K, Otterson GA, Villalona-Calero MA. PMID: 12767922.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter. Mol Cell Biol. 2003 Jun; 23(12):4056-65.
Zhu WG, Srinivasan K, Dai Z, Duan W, Druhan LJ, Ding H, Yee L, Villalona-Calero MA, Plass C, Otterson GA. PMID: 12773551; PMCID: PMC156121.
View in:
PubMed Mentions:
113 Fields:
Translation:
HumansCells
-
Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity. Ann Oncol. 2002 Dec; 13(12):1841-51.
Xu Y, Villalona-Calero MA. PMID: 12453851.
View in:
PubMed Mentions:
141 Fields:
Translation:
HumansAnimals
-
Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice. Oncogene. 2002 Nov 07; 21(51):7831-8.
Duan W, Ding H, Subler MA, Zhu WG, Zhang H, Stoner GD, Windle JJ, Otterson GA, Villalona-Calero MA. PMID: 12420220.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
-
Mitomycin as a modulator of irinotecan anticancer activity. Oncology (Williston Park). 2002 Aug; 16(8 Suppl 7):21-5.
Villalona-Calero MA, Kolesar JM. PMID: 12199629.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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RT-PCR heteroduplex analysis permits differentiation of transgene and host gene expression in a transgenic animal model. Biotechniques. 2002 Jul; 33(1):58, 60-2, 64 passim.
Duan W, Ding H, Zhu WG, Srinivasan K, Otterson GA, Villalona-Calero MA, Ottersom GA. PMID: 12139258.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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A phase I study of pivaloyloxymethyl butyrate, a prodrug of the differentiating agent butyric acid, in patients with advanced solid malignancies. Clin Cancer Res. 2002 Jul; 8(7):2142-8.
Patnaik A, Rowinsky EK, Villalona MA, Hammond LA, Britten CD, Siu LL, Goetz A, Felton SA, Burton S, Valone FH, Eckhardt SG. PMID: 12114414.
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PubMed Mentions:
30 Fields:
Translation:
HumansCTClinical Trials
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Pharmacobiologically based scheduling of capecitabine and docetaxel results in antitumor activity in resistant human malignancies. J Clin Oncol. 2002 Jun 01; 20(11):2616-23.
Nadella P, Shapiro C, Otterson GA, Hauger M, Erdal S, Kraut E, Clinton S, Shah M, Stanek M, Monk P, Villalona-Calero MA. PMID: 12039922.
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PubMed Mentions:
11 Fields:
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HumansCTClinical Trials
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A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer. Ann Oncol. 2002 Apr; 13(4):539-45.
Rudin CM, Otterson GA, Mauer AM, Villalona-Calero MA, Tomek R, Prange B, George CM, Szeto L, Vokes EE. PMID: 12056703.
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PubMed Mentions:
27 Fields:
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HumansCTClinical Trials
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Taxanes and capecitabine in combination: rationale and clinical results. Clin Breast Cancer. 2002 Jan; 2(4):287-93.
Maher JF, Villalona-Calero MA. PMID: 11899360.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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A phase I and pharmacokinetic study of ecteinascidin-743 on a daily x 5 schedule in patients with solid malignancies. Clin Cancer Res. 2002 Jan; 8(1):75-85.
Villalona-Calero MA, Eckhardt SG, Weiss G, Hidalgo M, Beijnen JH, van Kesteren C, Rosing H, Campbell E, Kraynak M, Lopez-Lazaro L, Guzman C, Von Hoff DD, Jimeno J, Rowinsky EK. PMID: 11801542.
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PubMed Mentions:
22 Fields:
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HumansCTClinical Trials
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Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells. Oncogene. 2001 Nov 22; 20(53):7787-96.
Zhu WG, Dai Z, Ding H, Srinivasan K, Hall J, Duan W, Villalona-Calero MA, Plass C, Otterson GA. PMID: 11753657.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Phase I dose-finding and pharmacokinetic trial of irinotecan (CPT-11) administered every two weeks. Ann Oncol. 2001 Nov; 12(11):1631-41.
Rothenberg ML, Kuhn JG, Schaaf LJ, Rodriguez GI, Eckhardt SG, Villalona-Calero MA, Rinaldi DA, Hammond LA, Hodges S, Sharma A, Elfring GL, Petit RG, Locker PK, Miller LL, von Hoff DD. PMID: 11822765.
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PubMed Mentions:
9 Fields:
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HumansCTClinical Trials
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A phase I and pharmacologic study of capecitabine and paclitaxel in breast cancer patients. Ann Oncol. 2001 May; 12(5):605-14.
Villalona-Calero MA, Blum JL, Jones SE, Diab S, Elledge R, Khoury P, Von Hoff D, Kraynak M, Moczygemba J, Kromelis P, Griffin T, Rowinsky EK. PMID: 11432617.
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PubMed Mentions:
6 Fields:
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HumansCTClinical Trials
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Phase I and pharmacokinetic study of LU79553, a DNA intercalating bisnaphthalimide, in patients with solid malignancies. J Clin Oncol. 2001 Feb 01; 19(3):857-69.
Villalona-Calero MA, Eder JP, Toppmeyer DL, Allen LF, Fram R, Velagapudi R, Myers M, Amato A, Kagen-Hallet K, Razvillas B, Kufe DW, Von Hoff DD, Rowinsky EK. PMID: 11157040.
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PubMed Mentions:
8 Fields:
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HumansCTClinical Trials
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Phase I and pharmacokinetic study of irofulven, a novel mushroom-derived cytotoxin, administered for five consecutive days every four weeks in patients with advanced solid malignancies. J Clin Oncol. 2000 Dec 15; 18(24):4086-97.
Eckhardt SG, Baker SD, Britten CD, Hidalgo M, Siu L, Hammond LA, Villalona-Calero MA, Felton S, Drengler R, Kuhn JG, Clark GM, Smith SL, MacDonald JR, Smith C, Moczygemba J, Weitman S, Von Hoff DD, Rowinsky EK. PMID: 11118470.
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11 Fields:
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Humans
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Phase I and pharmacologic study of PN401 and fluorouracil in patients with advanced solid malignancies. J Clin Oncol. 2000 Jan; 18(1):167-77.
Hidalgo M, Villalona-Calero MA, Eckhardt SG, Drengler RL, Rodriguez G, Hammond LA, Diab SG, Weiss G, Garner AM, Campbell E, Davidson K, Louie A, O'Neil JD, von Borstel R, Von Hoff DD, Rowinsky EK. PMID: 10623707.
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PubMed Mentions:
7 Fields:
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HumansCTClinical Trials
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A phase I and pharmacological study of protracted infusions of crisnatol mesylate in patients with solid malignancies. Clin Cancer Res. 1999 Nov; 5(11):3369-78.
Villalona-Calero MA, Petit T, Kuhn J, Cobb P, Kraynak M, Eckhardt SG, Drengler R, Simmons C, Santabarbara P, Von Hoff DD, Rowinsky EK. PMID: 10589747.
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PubMed Mentions:
1 Fields:
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HumansCTClinical Trials
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A Phase I and pharmacokinetic study of temozolomide and cisplatin in patients with advanced solid malignancies. Clin Cancer Res. 1999 Jul; 5(7):1629-37.
Britten CD, Rowinsky EK, Baker SD, Agarwala SS, Eckardt JR, Barrington R, Diab SG, Hammond LA, Johnson T, Villalona-Calero M, Fraass U, Statkevich P, Von Hoff DD, Eckhardt SG. PMID: 10430061.
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PubMed Mentions:
21 Fields:
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HumansCTClinical Trials
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Phase I and pharmacokinetic study of the oral fluoropyrimidine capecitabine in combination with paclitaxel in patients with advanced solid malignancies. J Clin Oncol. 1999 Jun; 17(6):1915-25.
Villalona-Calero MA, Weiss GR, Burris HA, Kraynak M, Rodrigues G, Drengler RL, Eckhardt SG, Reigner B, Moczygemba J, Burger HU, Griffin T, Von Hoff DD, Rowinsky EK. PMID: 10561233.
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PubMed Mentions:
20 Fields:
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HumansCTClinical Trials
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Phase I and pharmacologic study of the tyrosine kinase inhibitor SU101 in patients with advanced solid tumors. J Clin Oncol. 1999 Apr; 17(4):1095-104.
Eckhardt SG, Rizzo J, Sweeney KR, Cropp G, Baker SD, Kraynak MA, Kuhn JG, Villalona-Calero MA, Hammond L, Weiss G, Thurman A, Smith L, Drengler R, Eckardt JR, Moczygemba J, Hannah AL, Von Hoff DD, Rowinsky EK. PMID: 10561166.
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PubMed Mentions:
14 Fields:
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HumansCellsCTClinical Trials
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Phase I and pharmacokinetic trial of oral irinotecan administered daily for 5 days every 3 weeks in patients with solid tumors. J Clin Oncol. 1999 Feb; 17(2):685-96.
Drengler RL, Kuhn JG, Schaaf LJ, Rodriguez GI, Villalona-Calero MA, Hammond LA, Stephenson JA, Hodges S, Kraynak MA, Staton BA, Elfring GL, Locker PK, Miller LL, Von Hoff DD, Rothenberg ML. PMID: 10080615.
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PubMed Mentions:
24 Fields:
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HumansCTClinical Trials
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A phase I and pharmacokinetic study of losoxantrone and paclitaxel in patients with advanced solid tumors. Clin Cancer Res. 1999 Feb; 5(2):299-308.
Diab SG, Baker SD, Joshi A, Burris HA, Cobb PW, Villalona-Calero MA, Eckhardt SG, Weiss GR, Rodriguez GI, Drengler R, Kraynak M, Hammond L, Finizio M, Von Hoff DD, Rowinsky EK. PMID: 10037178.
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PubMed Mentions:
1 Fields:
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HumansCTClinical Trials
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New anticancer agents. Cancer Chemother Biol Response Modif. 1999; 18:178-209.
Britten C, Hammond L, Hidalgo M, Rothenberg ML, Sharma A, Sharma S, Siu L, Villalona-Calero M, Weiss GR. PMID: 10800483.
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HumansAnimalsCells
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Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP. J Clin Oncol. 1998 Sep; 16(9):2964-76.
Rowinsky EK, Smith L, Wang YM, Chaturvedi P, Villalona M, Campbell E, Aylesworth C, Eckhardt SG, Hammond L, Kraynak M, Drengler R, Stephenson J, Harding MW, Von Hoff DD. PMID: 9738565.
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PubMed Mentions:
31 Fields:
Translation:
HumansCTClinical Trials
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Alternative dosing schedules for irinotecan. Oncology (Williston Park). 1998 Aug; 12(8 Suppl 6):68-71.
Rothenberg ML, Kuhn JG, Schaaf LJ, Drengler RL, Eckhardt SG, Villalona-Calero MA, Hammond L, Miller LL, Petit RG, Rowinsky EK, Von Hoff DD. PMID: 9726095.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Phase I and pharmacokinetic study of the water-soluble dolastatin 15 analog LU103793 in patients with advanced solid malignancies. J Clin Oncol. 1998 Aug; 16(8):2770-9.
Villalona-Calero MA, Baker SD, Hammond L, Aylesworth C, Eckhardt SG, Kraynak M, Fram R, Fischkoff S, Velagapudi R, Toppmeyer D, Razvillas B, Jakimowicz K, Von Hoff DD, Rowinsky E. PMID: 9704730.
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PubMed Mentions:
1 Fields:
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HumansCTClinical Trials
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Phase I trial of paclitaxel and gemcitabine administered every two weeks in patients with refractory solid tumors. Ann Oncol. 1998 Jul; 9(7):733-8.
Rothenberg ML, Sharma A, Weiss GR, Villalona-Calero MA, Eckardt JR, Aylesworth C, Kraynak MA, Rinaldi DA, Rodriguez GI, Burris HA, Eckhardt SG, Stephens CD, Forral K, Nicol SJ, Von Hoff DD. PMID: 9739439.
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PubMed Mentions:
10 Fields:
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HumansCTClinical Trials
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A phase I trial of human corticotropin-releasing factor (hCRF) in patients with peritumoral brain edema. Ann Oncol. 1998 Jan; 9(1):71-7.
Villalona-Calero MA, Eckardt J, Burris H, Kraynak M, Fields-Jones S, Bazan C, Lancaster J, Hander T, Goldblum R, Hammond L, Bari A, Drengler R, Rothenberg M, Hadovsky G, Von Hoff DD. PMID: 9541686.
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PubMed Mentions:
10 Fields:
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HumansCTClinical Trials
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New anticancer agents in clinical development. Oncology (Williston Park). 1995 Dec; 9(12):1321-8; 1331; discussion 1332-4.
Eckardt J, Eckhardt G, Villalona-Calero M, Drengler R, Von Hoff D. PMID: 8771106.
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Translation:
Humans
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New anticancer agents in clinical development. Oncology (Williston Park). 1995 Nov; 9(11):1191-9.
Eckardt J, Eckhardt G, Villalona-Calero M, Drengler R, Von Hoff D. PMID: 8703688.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Secondary acute myelogenous leukemia in children with Latin-American ancestry. J Clin Oncol. 1993 Nov; 11(11):2286.
Villalona-Calero MA. PMID: 8229144.
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Humans
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Acute progranulocytic leukemia (APL): possible in vivo differentiation by granulocyte colony-stimulating factor (G-CSF). Leukemia. 1993 Oct; 7(10):1680-1.
Vaickus L, Villalona-Calero MA, Caligiuri T. PMID: 7692195.
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Humans
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Pretraining for international medical graduates. Ann Intern Med. 1993 Mar 01; 118(5):397-8.
Villalona-Calero M. PMID: 8430994.
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Humans
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Extragonadal abdominal germ cell cancers. Am J Clin Oncol. 1992 Aug; 15(4):308-10.
Gonzalez-Vela JL, Villalona-Calero MA, Torkelson JL, Fraley EE, Kennedy BJ. PMID: 1381144.
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PubMed Mentions:
2 Fields:
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HumansCTClinical Trials
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Management of testicular seminoma following organ transplantation. Med Pediatr Oncol. 1992; 20(4):338-40.
Villalona-Calero MA, Ducker T, Holasek M, Najarian J, Kennedy BJ. PMID: 1608358.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Pneumomediastinum complicating Pneumocystis carinii pneumonia in a patient with AIDS. Am J Med Sci. 1989 May; 297(5):328-30.
Villalona-Calero MA, Schrem SS, Phelps KR. PMID: 2785760.
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PubMed Mentions:
5 Fields:
Translation:
Humans