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Michael Craig Pirrung

Title(s)Professor, Pharmaceutical Sciences
Address101 Theory, Suite 100
Irvine CA 92697-3958
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    Collapse Research 
    Collapse Research Activities and Funding
    Sustainable Synthesis of Enfuvirtide
    NIH R21AI106597Jul 26, 2013 - Jun 30, 2016
    Role: Principal Investigator
    Medicinal Chemistry and Biology of Oral Insulin Mimics
    NIH R01DK060532Jul 15, 2003 - May 31, 2007
    Role: Principal Investigator
    COMBINATORIAL APPROACHES TO ANTI-SMALLPOX AGENTS
    NIH U01AI048521Aug 15, 2000 - Jul 31, 2004
    Role: Principal Investigator
    BIOORGANIC CHEMISTRY OF ANTIBACTERIALS
    NIH R01AI042151Sep 30, 1998 - Aug 31, 2002
    Role: Principal Investigator
    CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAM
    NIH T32GM008558Sep 1, 1994 - Jun 30, 2004
    Role: Principal Investigator
    BIOORGANIC PHOTOCHEMISTRY
    NIH R01GM046720Aug 1, 1992 - Sep 29, 2001
    Role: Principal Investigator
    MOLECULAR METAPHORS IN BIOORGANIC CHEMISTRY
    NIH R01GM043816Apr 1, 1991 - Jun 30, 1994
    Role: Principal Investigator
    METHODS FOR HETEROCYCLE SYNTHESIS
    NIH R01GM038226Apr 1, 1987 - Aug 31, 1989
    Role: Principal Investigator
    SYNTHESIS OF ANTITUMOR PENTALENOLACTONES
    NIH R01AI020485Jul 1, 1983 - Dec 31, 1986
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Synthetic Access to Cannabidiol and Analogs as Active Pharmaceutical Ingredients. J Med Chem. 2020 11 12; 63(21):12131-12136. Pirrung MC. PMID: 32531156.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Syrbactin proteasome inhibitor TIR-199 overcomes bortezomib chemoresistance and inhibits multiple myeloma tumor growth in vivo. Leuk Res. 2020 01; 88:106271. Pierce MR, Robinson RM, Ibarra-Rivera TR, Pirrung MC, Dolloff NG, Bachmann AS. PMID: 31778912.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Synthesis and bioluminescence of thioluciferin. Bioorg Med Chem Lett. 2019 10 01; 29(19):126591. Pirrung MC, Carlson AD, De Howitt N, Liao J. PMID: 31471166.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    4. Thiasyrbactins Induce Cell Death via Proteasome Inhibition in Multiple Myeloma Cells. Anticancer Res. 2018 Oct; 38(10):5607-5613. Pierce MR, Bakas NA, Pirrung MC, Bachmann AS. PMID: 30275178.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Immunoproteasome inhibition and bioactivity of thiasyrbactins. Bioorg Med Chem. 2018 01 15; 26(2):401-412. Bakas NA, Schultz CR, Yco LP, Roberts CC, Chang CA, Bachmann AS, Pirrung MC. PMID: 29269255.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. ß-Deuterium Isotope Effects on Firefly Luciferase Bioluminescence. ChemistryOpen. 2017 12; 6(6):697-700. Pirrung MC, Dorsey A, Howitt N, Liao J. PMID: 29226056.
      View in: PubMed   Mentions:
    7. Native Serine Peptide Assembly: Scope and Utility. European J Org Chem. 2016 Dec; 2016(34):5633-5636. Pirrung MC, Schreihans RS. PMID: 28111523.
      View in: PubMed   Mentions:
    8. Correction: Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation. Org Biomol Chem. 2016 09 26; 14(38):9159. Pirrung MC, Zhang F, Ambadi S, Gangadhara Rao Y. PMID: 27714303.
      View in: PubMed   Mentions:    Fields:    
    9. Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation. Org Biomol Chem. 2016 Sep 21; 14(35):8367-75. Pirrung MC, Zhang F, Ambadi S, Gangadhara Rao Y. PMID: 27533920.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    10. Syrbactin Structural Analog TIR-199 Blocks Proteasome Activity and Induces Tumor Cell Death. J Biol Chem. 2016 Apr 15; 291(16):8350-62. Bachmann AS, Opoku-Ansah J, Ibarra-Rivera TR, Yco LP, Ambadi S, Roberts CC, Chang CE, Pirrung MC. PMID: 26907687.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    11. Synthesis and bioluminescence of difluoroluciferin. Bioorg Med Chem Lett. 2014 Oct 15; 24(20):4881-3. Pirrung MC, Biswas G, De Howitt N, Liao J. PMID: 25239851.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    12. The genesis of microarrays. Biochem Mol Biol Educ. 2014 Mar-Apr; 42(2):106-13. Pirrung MC, Southern EM. PMID: 24344052.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Catalyzed Claisen rearrangements of O-allyl kojates. Tetrahedron Lett. 2013 Jul 17; 54(29). Pirrung MC, Nalbandian JN. PMID: 24187389.
      View in: PubMed   Mentions:    Fields:    
    14. Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I. PLoS One. 2013; 8(6):e65695. Thomas S, Sharma N, Gonzalez R, Pao PW, Hofman FM, Chen TC, Louie SG, Pirrung MC, Schönthal AH. PMID: 23755268.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    15. A fluorescent amino acid probe to monitor efficiency of peptide conjugation to glass surfaces for high density microarrays. Mol Biosyst. 2012 Mar; 8(3):879-87. Zhao Y, Pirrung MC, Liao J. PMID: 22241083.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    16. Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma. Pharm Biol. 2012 Jan; 50(1):25-9. Opoku-Ansah J, Ibarra-Rivera TR, Pirrung MC, Bachmann AS. PMID: 22196580.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    17. Novel proteasome-inhibitory syrbactin analogs inducing endoplasmic reticulum stress and apoptosis in hematological tumor cell lines. Biochem Pharmacol. 2011 Sep 15; 82(6):600-9. Anshu A, Thomas S, Agarwal P, Ibarra-Rivera TR, Pirrung MC, Schönthal AH. PMID: 21736873.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    18. Sensitized two-photon photochemical deprotection. Chem Commun (Camb). 2010 Aug 07; 46(29):5313-5. Pirrung MC, Dore TM, Zhu Y, Rana VS. PMID: 20552130.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    19. Total synthesis of syringolin A and B. Org Lett. 2010 May 21; 12(10):2402-5. Pirrung MC, Biswas G, Ibarra-Rivera TR. PMID: 20426399.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    20. His-tags lighten up and lose their inhibitions. Proc Natl Acad Sci U S A. 2010 Apr 06; 107(14):6123-4. Pirrung MC. PMID: 20363960.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    21. Iodine scanning of a phenazine inhibitor of vacuolar sorting. Bioorg Med Chem Lett. 2010 Mar 01; 20(5):1496-9. Surpin M, Zou Y, Xiong C, Raikhel NV, Pirrung MC. PMID: 20153185.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    22. Multicomponent reactions of convertible isonitriles. J Org Chem. 2009 Jun 05; 74(11):4110-7. Pirrung MC, Ghorai S, Ibarra-Rivera TR. PMID: 19408909.
      View in: PubMed   Mentions: 8     Fields:    
    23. Multicomponent reactions of cyclobutanones. J Org Chem. 2009 Apr 17; 74(8):2958-63. Pirrung MC, Wang J. PMID: 19354324.
      View in: PubMed   Mentions: 2     Fields:    
    24. Small molecule activators of the Trk receptors for neuroprotection. BMC Neurosci. 2008 Dec 03; 9 Suppl 2:S1. Webster NJ, Pirrung MC. PMID: 19090982.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    25. Hydrophobicity and mixing effects on select heterogeneous, water-accelerated synthetic reactions. J Org Chem. 2008 Nov 21; 73(22):8723-30. Pirrung MC, Das Sarma K, Wang J. PMID: 18954111.
      View in: PubMed   Mentions: 3     Fields:    
    26. Ethylene receptor antagonists: strained alkenes are necessary but not sufficient. Chem Biol. 2008 Apr; 15(4):313-21. Pirrung MC, Bleecker AB, Inoue Y, Rodríguez FI, Sugawara N, Wada T, Zou Y, Binder BM. PMID: 18420138.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    27. Preparation of methyl ester precursors of biologically active agents. Biotechniques. 2008 Mar; 44(3):377-84. Zou Y, Rojas-Pierce M, Raikhel N, Pirrung M. PMID: 18361791.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    28. Modular synthesis of candidate indole-based insulin mimics by Claisen rearrangement. Org Lett. 2008 Mar 20; 10(6):1151-4. Xiong X, Pirrung MC. PMID: 18303898.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    29. Quinone replacements for small molecule insulin mimics. Chembiochem. 2008 Feb 15; 9(3):360-2. Pirrung MC, Deng L, Lin B, Webster NJ. PMID: 18232038.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    30. Identification of novel orally available small molecule insulin mimetics. J Pharmacol Exp Ther. 2007 Nov; 323(2):579-85. Lin B, Li Z, Park K, Deng L, Pai A, Zhong L, Pirrung MC, Webster NJ. PMID: 17687071.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    31. Parallel synthesis of indolylquinones and their cell-based insulin mimicry. J Comb Chem. 2007 Sep-Oct; 9(5):844-54. Pirrung MC, Li Z, Hensley E, Liu Y, Tanksale A, Lin B, Pai A, Webster NJ. PMID: 17595147.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    32. Glyceraldehyde 3-phosphate dehydrogenase is a cellular target of the insulin mimic demethylasterriquinone B1. J Med Chem. 2007 Jul 26; 50(15):3423-6. Kim H, Deng L, Xiong X, Hunter WD, Long MC, Pirrung MC. PMID: 17595071.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    33. Practical synthesis of 7-prenylindole. J Org Chem. 2007 Jul 20; 72(15):5832-4. Xiong X, Pirrung MC. PMID: 17580906.
      View in: PubMed   Mentions: 1     Fields:    
    34. Neuroprotection by small molecule activators of the nerve growth factor receptor. J Pharmacol Exp Ther. 2007 Jul; 322(1):59-69. Lin B, Pirrung MC, Deng L, Li Z, Liu Y, Webster NJ. PMID: 17468299.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    35. Versatile, fragrant, convertible isonitriles. J Am Chem Soc. 2006 Sep 13; 128(36):11772-3. Pirrung MC, Ghorai S. PMID: 16953613.
      View in: PubMed   Mentions: 4     Fields:    
    36. Mechanistic studies on the photochemical deprotection of 3',5'-dimethoxybenzoin esters. Photochem Photobiol. 2006 Sep-Oct; 82(5):1258-64. Pirrung MC, Ye T, Zhou Z, Simon JD. PMID: 16752957.
      View in: PubMed   Mentions: 2     Fields:    
    37. Molecular validation of LpxC as an antibacterial drug target in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2006 Jun; 50(6):2178-84. Mdluli KE, Witte PR, Kline T, Barb AW, Erwin AL, Mansfield BE, McClerren AL, Pirrung MC, Tumey LN, Warrener P, Raetz CR, Stover CK. PMID: 16723580.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    38. Acceleration of organic reactions through aqueous solvent effects. Chemistry. 2006 Feb 01; 12(5):1312-7. Pirrung MC. PMID: 16189838.
      View in: PubMed   Mentions: 7     Fields:    
    39. Adding precision tools to the plant biologists' toolbox with chemical genomics. Plant Physiol. 2005 Jun; 138(2):563-4. Raikhel N, Pirrung M. PMID: 15955916.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    40. Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents. J Med Chem. 2005 Apr 21; 48(8):3045-50. Pirrung MC, Pansare SV, Sarma KD, Keith KA, Kern ER. PMID: 15828843.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    41. Methyl scanning: total synthesis of demethylasterriquinone B1 and derivatives for identification of sites of interaction with and isolation of its receptor(s). J Am Chem Soc. 2005 Apr 06; 127(13):4609-24. Pirrung MC, Liu Y, Deng L, Halstead DK, Li Z, May JF, Wedel M, Austin DA, Webster NJ. PMID: 15796526.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    42. Organometallic routes to 2,5-dihydroxy-3-(indol-3-yl)benzoquinones. Synthesis of demethylasterriquinone B4. J Org Chem. 2005 Apr 01; 70(7):2537-42. Pirrung MC, Fujita K, Park K. PMID: 15787540.
      View in: PubMed   Mentions: 3     Fields:    
    43. Benzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase. J Biol Chem. 2004 May 28; 279(22):23335-42. Yakovleva L, Handy CJ, Sayer JM, Pirrung M, Jerina DM, Shuman S. PMID: 15044474.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    44. Multicomponent reactions are accelerated in water. J Am Chem Soc. 2004 Jan 21; 126(2):444-5. Pirrung MC, Sarma KD. PMID: 14719923.
      View in: PubMed   Mentions: 20     Fields:    
    45. Combinatorial discovery of two-photon photoremovable protecting groups. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):12548-53. Pirrung MC, Pieper WH, Kaliappan KP, Dhananjeyan MR. PMID: 14557545.
      View in: PubMed   Mentions: 1     Fields:    
    46. Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones. J Med Chem. 2003 Jun 19; 46(13):2580-8. Sohn J, Kiburz B, Li Z, Deng L, Safi A, Pirrung MC, Rudolph J. PMID: 12801222.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    47. Modular, parallel synthesis of an illudinoid combinatorial library. Org Lett. 2003 May 29; 5(11):1983-5. Pirrung MC, Liu H. PMID: 12762702.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    48. Signaling effects of demethylasterriquinone B1, a selective insulin receptor modulator. Chembiochem. 2003 May 09; 4(5):379-85. Webster NJ, Park K, Pirrung MC. PMID: 12740809.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    49. High-throughput catch-and-release synthesis of oxazoline hydroxamates. Structure-activity relationships in novel inhibitors of Escherichia coli LpxC: in vitro enzyme inhibition and antibacterial properties. J Am Chem Soc. 2003 Feb 12; 125(6):1575-86. Pirrung MC, Tumey LN, McClerren AL, Raetz CR. PMID: 12568618.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    50. Synthesis of 2,5-dihydroxy-3-(indol-3-yl)benzoquinones by acid-catalyzed condensation of indoles with 2,5-dichlorobenzoquinone. J Org Chem. 2002 Nov 29; 67(24):8374-88. Pirrung MC, Deng L, Li Z, Park K. PMID: 12444614.
      View in: PubMed   Mentions: 3     Fields:    
    51. Total syntheses of demethylasterriquinone B1, an orally active insulin mimetic, and demethylasterriquinone A1. J Org Chem. 2002 Nov 15; 67(23):7919-26. Pirrung MC, Li Z, Park K, Zhu J. PMID: 12423119.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    52. Inhibition of the antibacterial target UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC): isoxazoline zinc amidase inhibitors bearing diverse metal binding groups. J Med Chem. 2002 Sep 12; 45(19):4359-70. Pirrung MC, Tumey LN, Raetz CR, Jackman JE, Snehalatha K, McClerren AL, Fierke CA, Gantt SL, Rusche KM. PMID: 12213077.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    53. (19)F-encoded combinatorial libraries: discovery of selective metal binding and catalytic peptoids. J Comb Chem. 2002 Jul-Aug; 4(4):329-44. Pirrung MC, Park K, Tumey LN. PMID: 12099851.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    54. Arrayed primer extension computing with variant mRNA splice forms. Multiple isoforms of CD44 in a human breast tumor. J Am Chem Soc. 2002 May 08; 124(18):4934-5. Kim H, Pirrung MC. PMID: 11982338.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    55. How to make a DNA chip. Angew Chem Int Ed Engl. 2002 Apr 15; 41(8):1276-89. Pirrung MC. PMID: 19750752.
      View in: PubMed   Mentions: 37     Fields:    
    56. Rhodium chemzymes: Michaelis-Menten kinetics in dirhodium(II) carboxylate-catalyzed carbenoid reactions. J Am Chem Soc. 2002 Feb 13; 124(6):1014-23. Pirrung MC, Liu H, Morehead AT. PMID: 11829610.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    57. Solid-phase, single nucleotide primer extension of DNA/RNA hybrids by reverse transcriptases. Bioorg Med Chem Lett. 2001 Sep 17; 11(18):2437-40. Pirrung MC, Worden JD, Labriola JP, Montague-Smith MP, Weislo LJ. PMID: 11549441.
      View in: PubMed   Mentions:    Fields:    
    58. APEX disease gene resequencing: mutations in exon 7 of the p53 tumor suppressor gene. Bioorg Med Chem. 2001 Sep; 9(9):2269-78. Shumaker JM, Tollet JJ, Filbin KJ, Montague-Smith MP, Pirrung MC. PMID: 11553465.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    59. Photochemically removable silyl protecting groups. J Am Chem Soc. 2001 Apr 25; 123(16):3638-43. Pirrung MC, Fallon L, Zhu J, Lee YR. PMID: 11457095.
      View in: PubMed   Mentions: 4     Fields:    
    60. 3'-nitrophenylpropyloxycarbonyl (NPPOC) protecting groups for high-fidelity automated 5' --> 3' photochemical DNA synthesis. Org Lett. 2001 Apr 19; 3(8):1105-8. Pirrung MC, Wang L, Montague-Smith MP. PMID: 11348170.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    61. A universal, photocleavable DNA base: nitropiperonyl 2'-deoxyriboside. J Org Chem. 2001 Mar 23; 66(6):2067-71. Pirrung MC, Zhao X, Harris SV. PMID: 11300902.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    62. Synthesis of 3-indolyl-2,5-dihydroxybenzoquinones. Org Lett. 2001 Feb 08; 3(3):365-7. Pirrung MC, Park K, Li Z. PMID: 11428015.
      View in: PubMed   Mentions: 2     Fields:    
    63. Trityl isothiocyanate support for solid-phase synthesis. J Comb Chem. 2001 Jan-Feb; 3(1):90-6. Pirrung MC, Pansare SV. PMID: 11148069.
      View in: PubMed   Mentions: 1     Fields:    
    64. Thiophosphorylation of histidine. J Org Chem. 2000 Dec 15; 65(25):8448-53. Pirrung MC, James KD, Rana VS. PMID: 11112562.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    65. Oxazoline synthesis from hydroxyamides by resin capture and ring-forming release. J Comb Chem. 2000 Nov-Dec; 2(6):675-80. Pirrung MC, Tumey LN. PMID: 11126295.
      View in: PubMed   Mentions: 4     Fields:    
    66. Discovery of selective metal-binding peptoids using 19F encoded combinatorial libraries. Bioorg Med Chem Lett. 2000 Sep 18; 10(18):2115-8. Pirrung MC, Park K. PMID: 10999483.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    67. Antibacterial agents that target lipid A biosynthesis in gram-negative bacteria. Inhibition of diverse UDP-3-O-(r-3-hydroxymyristoyl)-n-acetylglucosamine deacetylases by substrate analogs containing zinc binding motifs. J Biol Chem. 2000 Apr 14; 275(15):11002-9. Jackman JE, Fierke CA, Tumey LN, Pirrung M, Uchiyama T, Tahir SH, Hindsgaul O, Raetz CR. PMID: 10753902.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    68. Synthesis of (+/-)-homohistidine. J Org Chem. 2000 Apr 07; 65(7):2229-30. Pirrung MC, Pei T. PMID: 10774052.
      View in: PubMed   Mentions: 3     Fields:    
    69. Dipolar cycloaddition of rhodium-generated carbonyl ylides with p-quinones. Org Lett. 2000 Feb 10; 2(3):353-5. Pirrung MC, Kaliappan KP. PMID: 10814321.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    70. Histidine kinases and two-component signal transduction systems. Chem Biol. 1999 Jun; 6(6):R167-75. Pirrung MC. PMID: 10375545.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    71. Rhodium-Mediated Dipolar Cycloaddition of Diazoquinolinediones. J Org Chem. 1999 May 14; 64(10):3642-3649. Pirrung MC, Blume F. PMID: 11674492.
      View in: PubMed   Mentions: 5     Fields:    
    72. Ethylene biosynthesis: processing of a substrate analog supports a radical mechanism for the ethylene-forming enzyme. Chem Biol. 1998 Jan; 5(1):49-57. Pirrung MC, Cao J, Chen J. PMID: 9479479.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    73. Spatially Addressable Combinatorial Libraries. Chem Rev. 1997 Apr 01; 97(2):473-488. Pirrung MC. PMID: 11848879.
      View in: PubMed   Mentions: 10     Fields:    
    74. O-Alkyl Hydroxamates as Metaphors of Enzyme-Bound Enolate Intermediates in Hydroxy Acid Dehydrogenases. Inhibitors of Isopropylmalate Dehydrogenase, Isocitrate Dehydrogenase, and Tartrate Dehydrogenase(1). J Org Chem. 1996 Jul 12; 61(14):4527-4531. Pirrung MC, Han H, Chen J. PMID: 11667376.
      View in: PubMed   Mentions: 2     Fields:    
    75. A general method for the spatially defined immobilization of biomolecules on glass surfaces using "caged" biotin. Bioconjug Chem. 1996 May-Jun; 7(3):317-21. Pirrung MC, Huang CY. PMID: 8816954.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    76. Cofactor-Directed, Time-Dependent Inhibition of Thiamine Enzymes by the Fungal Toxin Moniliformin. J Org Chem. 1996 Apr 19; 61(8):2592-2593. Pirrung MC, Nauhaus SK, Singh B. PMID: 11667082.
      View in: PubMed   Mentions: 2     Fields:    
    77. Discovery of a novel tetrahydroacridine acetylcholinesterase inhibitor through an indexed combinatorial library. Chem Biol. 1995 Sep; 2(9):621-6. Pirrung MC, Chau JH, Chen J. PMID: 9383467.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    78. Purification and properties of the apple fruit ethylene-forming enzyme. Biochemistry. 1993 Jul 27; 32(29):7445-50. Pirrung MC, Kaiser LM, Chen J. PMID: 8338842.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    79. Light-directed, spatially addressable parallel chemical synthesis. Science. 1991 Feb 15; 251(4995):767-73. Fodor SP, Read JL, Pirrung MC, Stryer L, Lu AT, Solas D. PMID: 1990438.
      View in: PubMed   Mentions: 319     Fields:    Translation:Cells
    80. Intramolecular generation and [2,3]-sigmatropic rearrangement of oxonium ylides. J Am Chem Soc. 1986 Sep 01; 108(19):6060-2. Pirrung MC, Werner JA. PMID: 22175384.
      View in: PubMed   Mentions: 5     Fields:    
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