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Michael Craig Pirrung

Title(s)Professor, Pharmaceutical Sciences
Address101 Theory, Suite 100
Irvine CA 92697-3958
Emailpirrungm@uci.edu
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    Collapse Research 
    Collapse Research Activities and Funding
    Sustainable Synthesis of Enfuvirtide
    NIH/NIAID R21AI106597Jul 26, 2013 - Jun 30, 2015
    Role: Principal Investigator
    Medicinal Chemistry and Biology of Oral Insulin Mimics
    NIH/NIDDK R01DK060532Jul 15, 2003 - May 31, 2007
    Role: Principal Investigator
    COMBINATORIAL APPROACHES TO ANTI-SMALLPOX AGENTS
    NIH/NIAID U01AI048521Aug 15, 2000 - Jun 30, 2005
    Role: Principal Investigator
    BIOORGANIC CHEMISTRY OF ANTIBACTERIALS
    NIH/NIAID R01AI042151Sep 30, 1998 - Aug 31, 2002
    Role: Principal Investigator
    CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAM
    NIH/NIGMS T32GM008558Sep 1, 1994 - Jun 30, 2004
    Role: Principal Investigator
    BIOORGANIC PHOTOCHEMISTRY
    NIH/NIGMS R01GM046720Aug 1, 1992 - Sep 29, 2001
    Role: Principal Investigator
    MOLECULAR METAPHORS IN BIOORGANIC CHEMISTRY
    NIH/NIGMS R01GM043816Apr 1, 1991 - Mar 31, 1994
    Role: Principal Investigator
    METHODS FOR HETEROCYCLE SYNTHESIS
    NIH/NIGMS R01GM038226Apr 1, 1987 - Mar 31, 1990
    Role: Principal Investigator
    SYNTHESIS OF ANTITUMOR PENTALENOLACTONES
    NIH/NIAID R01AI020485Jul 1, 1983 - Dec 31, 1986
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Synthetic Access to Cannabidiol and Analogs as Active Pharmaceutical Ingredients. J Med Chem. 2020 Jul 13. Pirrung MC. PMID: 32531156.
      View in: PubMed   Mentions:    Fields:    
    2. Syrbactin proteasome inhibitor TIR-199 overcomes bortezomib chemoresistance and inhibits multiple myeloma tumor growth in vivo. Leuk Res. 2020 01; 88:106271. Pierce MR, Robinson RM, Ibarra-Rivera TR, Pirrung MC, Dolloff NG, Bachmann AS. PMID: 31778912.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Synthesis and bioluminescence of thioluciferin. Bioorg Med Chem Lett. 2019 10 01; 29(19):126591. Pirrung MC, Carlson AD, De Howitt N, Liao J. PMID: 31471166.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    4. Thiasyrbactins Induce Cell Death via Proteasome Inhibition in Multiple Myeloma Cells. Anticancer Res. 2018 Oct; 38(10):5607-5613. Pierce MR, Bakas NA, Pirrung MC, Bachmann AS. PMID: 30275178.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Immunoproteasome inhibition and bioactivity of thiasyrbactins. Bioorg Med Chem. 2018 01 15; 26(2):401-412. Bakas NA, Schultz CR, Yco LP, Roberts CC, Chang CA, Bachmann AS, Pirrung MC. PMID: 29269255.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. ß-Deuterium Isotope Effects on Firefly Luciferase Bioluminescence. ChemistryOpen. 2017 12; 6(6):697-700. Pirrung MC, Dorsey A, Howitt N, Liao J. PMID: 29226056.
      View in: PubMed   Mentions:
    7. Native Serine Peptide Assembly: Scope and Utility. European J Org Chem. 2016 Dec; 2016(34):5633-5636. Pirrung MC, Schreihans RS. PMID: 28111523.
      View in: PubMed   Mentions:
    8. Correction: Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation. Org Biomol Chem. 2016 09 26; 14(38):9159. Pirrung MC, Zhang F, Ambadi S, Gangadhara Rao Y. PMID: 27714303.
      View in: PubMed   Mentions:    Fields:    
    9. Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation. Org Biomol Chem. 2016 Sep 21; 14(35):8367-75. Pirrung MC, Zhang F, Ambadi S, Gangadhara Rao Y. PMID: 27533920.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    10. Syrbactin Structural Analog TIR-199 Blocks Proteasome Activity and Induces Tumor Cell Death. J Biol Chem. 2016 Apr 15; 291(16):8350-62. Bachmann AS, Opoku-Ansah J, Ibarra-Rivera TR, Yco LP, Ambadi S, Roberts CC, Chang CE, Pirrung MC. PMID: 26907687.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    11. Synthesis and bioluminescence of difluoroluciferin. Bioorg Med Chem Lett. 2014 Oct 15; 24(20):4881-3. Pirrung MC, Biswas G, De Howitt N, Liao J. PMID: 25239851.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    12. The genesis of microarrays. Biochem Mol Biol Educ. 2014 Mar-Apr; 42(2):106-13. Pirrung MC, Southern EM. PMID: 24344052.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Catalyzed Claisen rearrangements of O-allyl kojates. Tetrahedron Lett. 2013 Jul 17; 54(29). Pirrung MC, Nalbandian JN. PMID: 24187389.
      View in: PubMed   Mentions:    Fields:    
    14. Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I. PLoS One. 2013; 8(6):e65695. Thomas S, Sharma N, Gonzalez R, Pao PW, Hofman FM, Chen TC, Louie SG, Pirrung MC, Schönthal AH. PMID: 23755268.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    15. A fluorescent amino acid probe to monitor efficiency of peptide conjugation to glass surfaces for high density microarrays. Mol Biosyst. 2012 Mar; 8(3):879-87. Zhao Y, Pirrung MC, Liao J. PMID: 22241083.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    16. Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma. Pharm Biol. 2012 Jan; 50(1):25-9. Opoku-Ansah J, Ibarra-Rivera TR, Pirrung MC, Bachmann AS. PMID: 22196580.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    17. Novel proteasome-inhibitory syrbactin analogs inducing endoplasmic reticulum stress and apoptosis in hematological tumor cell lines. Biochem Pharmacol. 2011 Sep 15; 82(6):600-9. Anshu A, Thomas S, Agarwal P, Ibarra-Rivera TR, Pirrung MC, Schönthal AH. PMID: 21736873.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    18. Sensitized two-photon photochemical deprotection. Chem Commun (Camb). 2010 Aug 07; 46(29):5313-5. Pirrung MC, Dore TM, Zhu Y, Rana VS. PMID: 20552130.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    19. Total synthesis of syringolin A and B. Org Lett. 2010 May 21; 12(10):2402-5. Pirrung MC, Biswas G, Ibarra-Rivera TR. PMID: 20426399.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    20. His-tags lighten up and lose their inhibitions. Proc Natl Acad Sci U S A. 2010 Apr 06; 107(14):6123-4. Pirrung MC. PMID: 20363960.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    21. Iodine scanning of a phenazine inhibitor of vacuolar sorting. Bioorg Med Chem Lett. 2010 Mar 01; 20(5):1496-9. Surpin M, Zou Y, Xiong C, Raikhel NV, Pirrung MC. PMID: 20153185.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    22. Multicomponent reactions of convertible isonitriles. J Org Chem. 2009 Jun 05; 74(11):4110-7. Pirrung MC, Ghorai S, Ibarra-Rivera TR. PMID: 19408909.
      View in: PubMed   Mentions: 8     Fields:    
    23. Multicomponent reactions of cyclobutanones. J Org Chem. 2009 Apr 17; 74(8):2958-63. Pirrung MC, Wang J. PMID: 19354324.
      View in: PubMed   Mentions: 2     Fields:    
    24. Small molecule activators of the Trk receptors for neuroprotection. BMC Neurosci. 2008 Dec 03; 9 Suppl 2:S1. Webster NJ, Pirrung MC. PMID: 19090982.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    25. Hydrophobicity and mixing effects on select heterogeneous, water-accelerated synthetic reactions. J Org Chem. 2008 Nov 21; 73(22):8723-30. Pirrung MC, Das Sarma K, Wang J. PMID: 18954111.
      View in: PubMed   Mentions: 2     Fields:    
    26. Ethylene receptor antagonists: strained alkenes are necessary but not sufficient. Chem Biol. 2008 Apr; 15(4):313-21. Pirrung MC, Bleecker AB, Inoue Y, Rodríguez FI, Sugawara N, Wada T, Zou Y, Binder BM. PMID: 18420138.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    27. Preparation of methyl ester precursors of biologically active agents. Biotechniques. 2008 Mar; 44(3):377-84. Zou Y, Rojas-Pierce M, Raikhel N, Pirrung M. PMID: 18361791.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    28. Modular synthesis of candidate indole-based insulin mimics by Claisen rearrangement. Org Lett. 2008 Mar 20; 10(6):1151-4. Xiong X, Pirrung MC. PMID: 18303898.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    29. Quinone replacements for small molecule insulin mimics. Chembiochem. 2008 Feb 15; 9(3):360-2. Pirrung MC, Deng L, Lin B, Webster NJ. PMID: 18232038.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    30. Identification of novel orally available small molecule insulin mimetics. J Pharmacol Exp Ther. 2007 Nov; 323(2):579-85. Lin B, Li Z, Park K, Deng L, Pai A, Zhong L, Pirrung MC, Webster NJ. PMID: 17687071.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    31. Parallel synthesis of indolylquinones and their cell-based insulin mimicry. J Comb Chem. 2007 Sep-Oct; 9(5):844-54. Pirrung MC, Li Z, Hensley E, Liu Y, Tanksale A, Lin B, Pai A, Webster NJ. PMID: 17595147.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    32. Glyceraldehyde 3-phosphate dehydrogenase is a cellular target of the insulin mimic demethylasterriquinone B1. J Med Chem. 2007 Jul 26; 50(15):3423-6. Kim H, Deng L, Xiong X, Hunter WD, Long MC, Pirrung MC. PMID: 17595071.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    33. Practical synthesis of 7-prenylindole. J Org Chem. 2007 Jul 20; 72(15):5832-4. Xiong X, Pirrung MC. PMID: 17580906.
      View in: PubMed   Mentions: 1     Fields:    
    34. Neuroprotection by small molecule activators of the nerve growth factor receptor. J Pharmacol Exp Ther. 2007 Jul; 322(1):59-69. Lin B, Pirrung MC, Deng L, Li Z, Liu Y, Webster NJ. PMID: 17468299.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    35. Versatile, fragrant, convertible isonitriles. J Am Chem Soc. 2006 Sep 13; 128(36):11772-3. Pirrung MC, Ghorai S. PMID: 16953613.
      View in: PubMed   Mentions: 4     Fields:    
    36. Mechanistic studies on the photochemical deprotection of 3',5'-dimethoxybenzoin esters. Photochem Photobiol. 2006 Sep-Oct; 82(5):1258-64. Pirrung MC, Ye T, Zhou Z, Simon JD. PMID: 16752957.
      View in: PubMed   Mentions: 2     Fields:    
    37. Molecular validation of LpxC as an antibacterial drug target in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2006 Jun; 50(6):2178-84. Mdluli KE, Witte PR, Kline T, Barb AW, Erwin AL, Mansfield BE, McClerren AL, Pirrung MC, Tumey LN, Warrener P, Raetz CR, Stover CK. PMID: 16723580.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    38. Acceleration of organic reactions through aqueous solvent effects. Chemistry. 2006 Feb 01; 12(5):1312-7. Pirrung MC. PMID: 16189838.
      View in: PubMed   Mentions: 5     Fields:    
    39. Adding precision tools to the plant biologists' toolbox with chemical genomics. Plant Physiol. 2005 Jun; 138(2):563-4. Raikhel N, Pirrung M. PMID: 15955916.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    40. Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents. J Med Chem. 2005 Apr 21; 48(8):3045-50. Pirrung MC, Pansare SV, Sarma KD, Keith KA, Kern ER. PMID: 15828843.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    41. Methyl scanning: total synthesis of demethylasterriquinone B1 and derivatives for identification of sites of interaction with and isolation of its receptor(s). J Am Chem Soc. 2005 Apr 06; 127(13):4609-24. Pirrung MC, Liu Y, Deng L, Halstead DK, Li Z, May JF, Wedel M, Austin DA, Webster NJ. PMID: 15796526.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    42. Organometallic routes to 2,5-dihydroxy-3-(indol-3-yl)benzoquinones. Synthesis of demethylasterriquinone B4. J Org Chem. 2005 Apr 01; 70(7):2537-42. Pirrung MC, Fujita K, Park K. PMID: 15787540.
      View in: PubMed   Mentions: 3     Fields:    
    43. Benzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase. J Biol Chem. 2004 May 28; 279(22):23335-42. Yakovleva L, Handy CJ, Sayer JM, Pirrung M, Jerina DM, Shuman S. PMID: 15044474.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    44. Multicomponent reactions are accelerated in water. J Am Chem Soc. 2004 Jan 21; 126(2):444-5. Pirrung MC, Sarma KD. PMID: 14719923.
      View in: PubMed   Mentions: 17     Fields:    
    45. Combinatorial discovery of two-photon photoremovable protecting groups. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):12548-53. Pirrung MC, Pieper WH, Kaliappan KP, Dhananjeyan MR. PMID: 14557545.
      View in: PubMed   Mentions: 1     Fields:    
    46. Inhibition of Cdc25 phosphatases by indolyldihydroxyquinones. J Med Chem. 2003 Jun 19; 46(13):2580-8. Sohn J, Kiburz B, Li Z, Deng L, Safi A, Pirrung MC, Rudolph J. PMID: 12801222.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    47. Modular, parallel synthesis of an illudinoid combinatorial library. Org Lett. 2003 May 29; 5(11):1983-5. Pirrung MC, Liu H. PMID: 12762702.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    48. Signaling effects of demethylasterriquinone B1, a selective insulin receptor modulator. Chembiochem. 2003 May 09; 4(5):379-85. Webster NJ, Park K, Pirrung MC. PMID: 12740809.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    49. High-throughput catch-and-release synthesis of oxazoline hydroxamates. Structure-activity relationships in novel inhibitors of Escherichia coli LpxC: in vitro enzyme inhibition and antibacterial properties. J Am Chem Soc. 2003 Feb 12; 125(6):1575-86. Pirrung MC, Tumey LN, McClerren AL, Raetz CR. PMID: 12568618.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    50. Synthesis of 2,5-dihydroxy-3-(indol-3-yl)benzoquinones by acid-catalyzed condensation of indoles with 2,5-dichlorobenzoquinone. J Org Chem. 2002 Nov 29; 67(24):8374-88. Pirrung MC, Deng L, Li Z, Park K. PMID: 12444614.
      View in: PubMed   Mentions: 3     Fields:    
    51. Total syntheses of demethylasterriquinone B1, an orally active insulin mimetic, and demethylasterriquinone A1. J Org Chem. 2002 Nov 15; 67(23):7919-26. Pirrung MC, Li Z, Park K, Zhu J. PMID: 12423119.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    52. Inhibition of the antibacterial target UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC): isoxazoline zinc amidase inhibitors bearing diverse metal binding groups. J Med Chem. 2002 Sep 12; 45(19):4359-70. Pirrung MC, Tumey LN, Raetz CR, Jackman JE, Snehalatha K, McClerren AL, Fierke CA, Gantt SL, Rusche KM. PMID: 12213077.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    53. (19)F-encoded combinatorial libraries: discovery of selective metal binding and catalytic peptoids. J Comb Chem. 2002 Jul-Aug; 4(4):329-44. Pirrung MC, Park K, Tumey LN. PMID: 12099851.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    54. Arrayed primer extension computing with variant mRNA splice forms. Multiple isoforms of CD44 in a human breast tumor. J Am Chem Soc. 2002 May 08; 124(18):4934-5. Kim H, Pirrung MC. PMID: 11982338.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    55. How to make a DNA chip. Angew Chem Int Ed Engl. 2002 Apr 15; 41(8):1276-89. Pirrung MC. PMID: 19750752.
      View in: PubMed   Mentions: 37     Fields:    
    56. Rhodium chemzymes: Michaelis-Menten kinetics in dirhodium(II) carboxylate-catalyzed carbenoid reactions. J Am Chem Soc. 2002 Feb 13; 124(6):1014-23. Pirrung MC, Liu H, Morehead AT. PMID: 11829610.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    57. Solid-phase, single nucleotide primer extension of DNA/RNA hybrids by reverse transcriptases. Bioorg Med Chem Lett. 2001 Sep 17; 11(18):2437-40. Pirrung MC, Worden JD, Labriola JP, Montague-Smith MP, Weislo LJ. PMID: 11549441.
      View in: PubMed   Mentions:    Fields:    
    58. APEX disease gene resequencing: mutations in exon 7 of the p53 tumor suppressor gene. Bioorg Med Chem. 2001 Sep; 9(9):2269-78. Shumaker JM, Tollet JJ, Filbin KJ, Montague-Smith MP, Pirrung MC. PMID: 11553465.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    59. Photochemically removable silyl protecting groups. J Am Chem Soc. 2001 Apr 25; 123(16):3638-43. Pirrung MC, Fallon L, Zhu J, Lee YR. PMID: 11457095.
      View in: PubMed   Mentions: 4     Fields:    
    60. 3'-nitrophenylpropyloxycarbonyl (NPPOC) protecting groups for high-fidelity automated 5' --> 3' photochemical DNA synthesis. Org Lett. 2001 Apr 19; 3(8):1105-8. Pirrung MC, Wang L, Montague-Smith MP. PMID: 11348170.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    61. A universal, photocleavable DNA base: nitropiperonyl 2'-deoxyriboside. J Org Chem. 2001 Mar 23; 66(6):2067-71. Pirrung MC, Zhao X, Harris SV. PMID: 11300902.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    62. Synthesis of 3-indolyl-2,5-dihydroxybenzoquinones. Org Lett. 2001 Feb 08; 3(3):365-7. Pirrung MC, Park K, Li Z. PMID: 11428015.
      View in: PubMed   Mentions: 2     Fields:    
    63. Trityl isothiocyanate support for solid-phase synthesis. J Comb Chem. 2001 Jan-Feb; 3(1):90-6. Pirrung MC, Pansare SV. PMID: 11148069.
      View in: PubMed   Mentions: 1     Fields:    
    64. Thiophosphorylation of histidine. J Org Chem. 2000 Dec 15; 65(25):8448-53. Pirrung MC, James KD, Rana VS. PMID: 11112562.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    65. Oxazoline synthesis from hydroxyamides by resin capture and ring-forming release. J Comb Chem. 2000 Nov-Dec; 2(6):675-80. Pirrung MC, Tumey LN. PMID: 11126295.
      View in: PubMed   Mentions: 4     Fields:    
    66. Discovery of selective metal-binding peptoids using 19F encoded combinatorial libraries. Bioorg Med Chem Lett. 2000 Sep 18; 10(18):2115-8. Pirrung MC, Park K. PMID: 10999483.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    67. Antibacterial agents that target lipid A biosynthesis in gram-negative bacteria. Inhibition of diverse UDP-3-O-(r-3-hydroxymyristoyl)-n-acetylglucosamine deacetylases by substrate analogs containing zinc binding motifs. J Biol Chem. 2000 Apr 14; 275(15):11002-9. Jackman JE, Fierke CA, Tumey LN, Pirrung M, Uchiyama T, Tahir SH, Hindsgaul O, Raetz CR. PMID: 10753902.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    68. Synthesis of (+/-)-homohistidine. J Org Chem. 2000 Apr 07; 65(7):2229-30. Pirrung MC, Pei T. PMID: 10774052.
      View in: PubMed   Mentions: 3     Fields:    
    69. Dipolar cycloaddition of rhodium-generated carbonyl ylides with p-quinones. Org Lett. 2000 Feb 10; 2(3):353-5. Pirrung MC, Kaliappan KP. PMID: 10814321.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    70. Histidine kinases and two-component signal transduction systems. Chem Biol. 1999 Jun; 6(6):R167-75. Pirrung MC. PMID: 10375545.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    71. Rhodium-Mediated Dipolar Cycloaddition of Diazoquinolinediones. J Org Chem. 1999 May 14; 64(10):3642-3649. Pirrung MC, Blume F. PMID: 11674492.
      View in: PubMed   Mentions: 5     Fields:    
    72. Ethylene biosynthesis: processing of a substrate analog supports a radical mechanism for the ethylene-forming enzyme. Chem Biol. 1998 Jan; 5(1):49-57. Pirrung MC, Cao J, Chen J. PMID: 9479479.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    73. Spatially Addressable Combinatorial Libraries. Chem Rev. 1997 Apr 01; 97(2):473-488. Pirrung MC. PMID: 11848879.
      View in: PubMed   Mentions: 10     Fields:    
    74. O-Alkyl Hydroxamates as Metaphors of Enzyme-Bound Enolate Intermediates in Hydroxy Acid Dehydrogenases. Inhibitors of Isopropylmalate Dehydrogenase, Isocitrate Dehydrogenase, and Tartrate Dehydrogenase(1). J Org Chem. 1996 Jul 12; 61(14):4527-4531. Pirrung MC, Han H, Chen J. PMID: 11667376.
      View in: PubMed   Mentions: 2     Fields:    
    75. A general method for the spatially defined immobilization of biomolecules on glass surfaces using "caged" biotin. Bioconjug Chem. 1996 May-Jun; 7(3):317-21. Pirrung MC, Huang CY. PMID: 8816954.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    76. Cofactor-Directed, Time-Dependent Inhibition of Thiamine Enzymes by the Fungal Toxin Moniliformin. J Org Chem. 1996 Apr 19; 61(8):2592-2593. Pirrung MC, Nauhaus SK, Singh B. PMID: 11667082.
      View in: PubMed   Mentions: 2     Fields:    
    77. Discovery of a novel tetrahydroacridine acetylcholinesterase inhibitor through an indexed combinatorial library. Chem Biol. 1995 Sep; 2(9):621-6. Pirrung MC, Chau JH, Chen J. PMID: 9383467.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    78. Purification and properties of the apple fruit ethylene-forming enzyme. Biochemistry. 1993 Jul 27; 32(29):7445-50. Pirrung MC, Kaiser LM, Chen J. PMID: 8338842.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    79. Light-directed, spatially addressable parallel chemical synthesis. Science. 1991 Feb 15; 251(4995):767-73. Fodor SP, Read JL, Pirrung MC, Stryer L, Lu AT, Solas D. PMID: 1990438.
      View in: PubMed   Mentions: 308     Fields:    Translation:Cells
    80. Intramolecular generation and [2,3]-sigmatropic rearrangement of oxonium ylides. J Am Chem Soc. 1986 Sep 01; 108(19):6060-2. Pirrung MC, Werner JA. PMID: 22175384.
      View in: PubMed   Mentions: 5     Fields:    
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