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Real-World Experience of Combined Treatment with Azacitidine and Romidepsin in Patients with Peripheral T-Cell Lymphoma. Blood Adv. 2023 Feb 15.
Kalac M, Jain S, Tam CS, Xiao Z, Montanari F, Kanakry JA, Huber BD, Goldfinger M, O'Connor OA, Marchi E. PMID: 36790924.
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N-quinoline-benzenesulfonamide derivatives exert potent anti-lymphoma effect by targeting NF-κB. iScience. 2020 Dec 18; 23(12):101884.
Kalac M, Mangone M, Rinderspacher A, Deng SX, Scotto L, Markson M, Bansal M, Califano A, Landry DW, O'Connor OA. PMID: 33354662; PMCID: PMC7744703.
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Acute cardiomyopathy following a single dose of doxorubicin in a patient with adult T-Cell leukemia/lymphoma. J Oncol Pharm Pract. 2021 Jun; 27(4):1011-1015.
Farina K, Kalac M, Kim S. PMID: 32869692.
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Humans
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Reversal of CYLD phosphorylation as a novel therapeutic approach for adult T-cell leukemia/lymphoma (ATLL). Cell Death Dis. 2020 02 05; 11(2):94.
Xu X, Kalac M, Markson M, Chan M, Brody JD, Bhagat G, Ang RL, Legarda D, Justus SJ, Liu F, Li Q, Xiong H, Ting AT. PMID: 32024820; PMCID: PMC7002447.
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15 Fields:
Translation:
HumansCells
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Brentuximab vedotin plus bendamustine in relapsed or refractory Hodgkin's lymphoma: an international, multicentre, single-arm, phase 1-2 trial. Lancet Oncol. 2018 02; 19(2):257-266.
O'Connor OA, Lue JK, Sawas A, Amengual JE, Deng C, Kalac M, Falchi L, Marchi E, Turenne I, Lichtenstein R, Rojas C, Francescone M, Schwartz L, Cheng B, Savage KJ, Villa D, Crump M, Prica A, Kukreti V, Cremers S, Connors JM, Kuruvilla J. PMID: 29276022; PMCID: PMC9098158.
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46 Fields:
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HumansCTClinical Trials
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A phase 1 study of romidepsin and pralatrexate reveals marked activity in relapsed and refractory T-cell lymphoma. Blood. 2018 01 25; 131(4):397-407.
Amengual JE, Lichtenstein R, Lue J, Sawas A, Deng C, Lichtenstein E, Khan K, Atkins L, Rada A, Kim HA, Chiuzan C, Kalac M, Marchi E, Falchi L, Francescone MA, Schwartz L, Cremers S, O'Connor OA. PMID: 29141948; PMCID: PMC5790128.
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46 Fields:
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HumansCTClinical Trials
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An Update on the Use of Immunotherapy in the Treatment of Lymphoma. Curr Hematol Malig Rep. 2017 08; 12(4):282-289.
Marron TU, Kalac M, Brody J. PMID: 28735365.
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1 Fields:
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Humans
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Brentuximab vedotin and bendamustine produce high complete response rates in patients with chemotherapy refractory Hodgkin lymphoma. Br J Haematol. 2018 03; 180(5):757-760.
Kalac M, Lue JK, Lichtenstein E, Turenne I, Rojas C, Amengual JE, Sawas A, Deng C, Mapara MY, Connors JM, Kuruvilla J, O'Connor OA. PMID: 27984643.
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7 Fields:
Translation:
Humans
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The combination of hypomethylating agents and histone deacetylase inhibitors produce marked synergy in preclinical models of T-cell lymphoma. Br J Haematol. 2015 Oct; 171(2):215-226.
Marchi E, Zullo KM, Amengual JE, Kalac M, Bongero D, McIntosh CM, Fogli LK, Rossi M, Zinzani PL, Pileri SA, Piccaluga PP, Fuligni F, Scotto L, O'Connor OA. PMID: 26194163.
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20 Fields:
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Propolis and its Active Component, Caffeic Acid Phenethyl Ester (CAPE), Modulate Breast Cancer Therapeutic Targets via an Epigenetically Mediated Mechanism of Action. J Cancer Sci Ther. 2013 Oct 21; 5(10):334-342.
Omene C, Kalac M, Wu J, Marchi E, Frenkel K, O'Connor OA. PMID: 24466386; PMCID: PMC3898618.
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27
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Sirtuin and pan-class I/II deacetylase (DAC) inhibition is synergistic in preclinical models and clinical studies of lymphoma. Blood. 2013 Sep 19; 122(12):2104-13.
Amengual JE, Clark-Garvey S, Kalac M, Scotto L, Marchi E, Neylon E, Johannet P, Wei Y, Zain J, O'Connor OA. PMID: 23913470.
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Development and characterization of a novel CD19CherryLuciferase (CD19CL) transgenic mouse for the preclinical study of B-cell lymphomas. Clin Cancer Res. 2012 Jul 15; 18(14):3803-11.
Scotto L, Kruithof-de Julio M, Paoluzzi L, Kalac M, Marchi E, Buitrago JB, Amengual J, Shen MM, O'Connor OA. PMID: 22589392.
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5 Fields:
Translation:
HumansAnimalsCells
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HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL. Blood. 2011 Nov 17; 118(20):5506-16.
Kalac M, Scotto L, Marchi E, Amengual J, Seshan VE, Bhagat G, Ulahannan N, Leshchenko VV, Temkin AM, Parekh S, Tycko B, O'Connor OA. PMID: 21772049; PMCID: PMC3217353.
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PubMed Mentions:
70 Fields:
Translation:
HumansAnimalsCells
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[Autologous stem cell transplantation in patients with relapsed or refractory Hodgkin's disease]. Acta Med Croatica. 2009 Jun; 63(3):215-7.
Minigo H, Vrhovac R, Kalac M, Jaksic B. PMID: 19827348.
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Humans
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New drugs for the treatment of lymphoma. Hematol Oncol Clin North Am. 2008 Oct; 22(5):1007-35, x.
Paoluzzi L, Kitagawa Y, Kalac M, Zain J, O'Connor OA. PMID: 18954749.
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PubMed Mentions:
3 Fields:
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Humans
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A critical appraisal of conventional and investigational drug therapy in patients with hypereosinophilic syndrome and clonal eosinophilia. Cancer. 2007 Sep 01; 110(5):955-64.
Kalac M, Quintás-Cardama A, Vrhovac R, Kantarjian H, Verstovsek S. PMID: 17654661.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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[The disappearance of CD20 positive lymphocytes in the pleural effusion after intrapleural application of rituximab]. Acta Med Croatica. 2007 Sep; 61(4):425-7.
Kalac M, Kolonic SO, Kardum-Skelin I, Planinc-Peraica A, Siftar Z, Jaksic B. PMID: 18044481.
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HumansCells
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Central nervous system involvement of previously undiagnosed chronic lymphocytic leukemia in a patient with neuroborreliosis. Int J Hematol. 2007 May; 85(4):323-5.
Kalac M, Suvic-Krizanic V, Ostojic S, Kardum-Skelin I, Barsic B, Jaksica B. PMID: 17483076.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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[Microcellular lung carcinoma in patient with hepatosplenic T-cell lymphoma: a case report]. Lijec Vjesn. 2006 Mar-Apr; 128(3-4):76-8.
Kalac M, Ostojic S, Gasparov S, Planinc-Peraica A, Dominis M, Jaksic B. PMID: 16808095.
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Translation:
Humans