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Fiandaca, Massimo S

TitleAssociate Professor In Residence
InstitutionUniversity of California, Irvine
DepartmentNeurology
Address1001 Health Sciences Road
CA 92697-3950
Phone(949) 824-5579
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Fiandaca M, Mapstone M, Mahmoodi A, Gross T, Macciardi F, Cheema AK, Merchant-Borna K, Bazarian J, Federoff HJ. Plasma metabolomic biomarkers accurately classify acute mild traumatic brain injury from controls. PLoS One. 2018; 13(4):e0195318. PMID: 29677216.
      View in: PubMed
    2. Hampel H, Vergallo A, Aguilar LF, Benda N, Broich K, Cuello AC, Cummings J, Dubois B, Federoff HJ, Fiandaca M, Genthon R, Haberkamp M, Karran E, Mapstone M, Perry G, Schneider LS, Welikovitch LA, Woodcock J, Baldacci F, Lista S. Precision pharmacology for Alzheimer's disease. Pharmacol Res. 2018 Apr; 130:331-365. PMID: 29458203.
      View in: PubMed
    3. Fiandaca M, Mapstone M, Connors E, Jacobson M, Monuki ES, Malik S, Macciardi F, Federoff HJ. Systems healthcare: a holistic paradigm for tomorrow. BMC Syst Biol. 2017 Dec 19; 11(1):142. PMID: 29258513.
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    4. Mehta KY, Wu HJ, Menon SS, Fallah Y, Zhong X, Rizk N, Unger K, Mapstone M, Fiandaca M, Federoff HJ, Cheema AK. Metabolomic biomarkers of pancreatic cancer: a meta-analysis study. Oncotarget. 2017 Sep 15; 8(40):68899-68915. PMID: 28978166.
      View in: PubMed
    5. Mapstone M, Cheema AK, Zhong X, Fiandaca M, Federoff HJ. Biomarker validation: Methods and matrix matter. Alzheimers Dement. 2017 05; 13(5):608-609. PMID: 28010950.
      View in: PubMed
    6. Mapstone M, Lin F, Nalls MA, Cheema AK, Singleton AB, Fiandaca M, Federoff HJ. What success can teach us about failure: the plasma metabolome of older adults with superior memory and lessons for Alzheimer's disease. Neurobiol Aging. 2017 Mar; 51:148-155. PMID: 27939698.
      View in: PubMed
    7. Fiandaca M, Zhong X, Cheema AK, Orquiza MH, Chidambaram S, Tan MT, Gresenz CR, FitzGerald KT, Nalls MA, Singleton AB, Mapstone M, Federoff HJ. Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer's Disease. Front Neurol. 2015; 6:237. PMID: 26617567; PMCID: PMC4642213.
    8. Nalls MA, McLean CY, Rick J, Eberly S, Hutten SJ, Gwinn K, Sutherland M, Martinez M, Heutink P, Williams NM, Hardy J, Gasser T, Brice A, Price TR, Nicolas A, Keller MF, Molony C, Gibbs JR, Chen-Plotkin A, Suh E, Letson C, Fiandaca M, Mapstone M, Federoff HJ, Noyce AJ, Morris H, Van Deerlin VM, Weintraub D, Zabetian C, Hernandez DG, Lesage S, Mullins M, Conley ED, Northover CA, Frasier M, Marek K, Day-Williams AG, Stone DJ, Ioannidis JP, Singleton AB. Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study. Lancet Neurol. 2015 Oct; 14(10):1002-9. PMID: 26271532.
      View in: PubMed
    9. Dromerick AW, Edwardson MA, Edwards DF, Giannetti ML, Barth J, Brady KP, Chan E, Tan MT, Tamboli I, Chia R, Orquiza M, Padilla RM, Cheema AK, Mapstone ME, Fiandaca M, Federoff HJ, Newport EL. Critical periods after stroke study: translating animal stroke recovery experiments into a clinical trial. Front Hum Neurosci. 2015; 9:231. PMID: 25972803; PMCID: PMC4413691.
    10. Fiandaca M, Kapogiannis D, Mapstone M, Boxer A, Eitan E, Schwartz JB, Abner EL, Petersen RC, Federoff HJ, Miller BL, Goetzl EJ. Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study. Alzheimers Dement. 2015 Jun; 11(6):600-7.e1. PMID: 25130657.
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    11. Fiandaca M, Mapstone ME, Cheema AK, Federoff HJ. The critical need for defining preclinical biomarkers in Alzheimer's disease. Alzheimers Dement. 2014 Jun; 10(3 Suppl):S196-212. PMID: 24924671.
      View in: PubMed
    12. Passini MA, Bu J, Richards AM, Treleaven CM, Sullivan JA, O'Riordan CR, Scaria A, Kells AP, Samaranch L, San Sebastian W, Federici T, Fiandaca M, Boulis NM, Bankiewicz KS, Shihabuddin LS, Cheng SH. Translational fidelity of intrathecal delivery of self-complementary AAV9-survival motor neuron 1 for spinal muscular atrophy. Hum Gene Ther. 2014 Jul; 25(7):619-30. PMID: 24617515.
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    13. Mapstone M, Cheema AK, Fiandaca M, Zhong X, Mhyre TR, MacArthur LH, Hall WJ, Fisher SG, Peterson DR, Haley JM, Nazar MD, Rich SA, Berlau DJ, Peltz CB, Tan MT, Kawas CH, Federoff HJ. Plasma phospholipids identify antecedent memory impairment in older adults. Nat Med. 2014 Apr; 20(4):415-8. PMID: 24608097.
      View in: PubMed
    14. Fiandaca M, Federoff HJ. Using viral-mediated gene delivery to model Parkinson's disease: do nonhuman primate investigations expand our understanding? Exp Neurol. 2014 Jun; 256:117-25. PMID: 23524194.
      View in: PubMed
    15. Fiandaca M, Bankiewicz KS, Federoff HJ. Gene therapy for the treatment of Parkinson's disease: the nature of the biologics expands the future indications. Pharmaceuticals (Basel). 2012 Jun 04; 5(6):553-90. PMID: 24281662; PMCID: PMC3763661.
    16. Ziegler RJ, Salegio EA, Dodge JC, Bringas J, Treleaven CM, Bercury SD, Tamsett TJ, Shihabuddin L, Hadaczek P, Fiandaca M, Bankiewicz K, Scheule RK. Distribution of acid sphingomyelinase in rodent and non-human primate brain after intracerebroventricular infusion. Exp Neurol. 2011 Oct; 231(2):261-71. PMID: 21777586.
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    17. Fiandaca M, Berger MS, Bankiewicz KS. The use of convection-enhanced delivery with liposomal toxins in neurooncology. Toxins (Basel). 2011 04; 3(4):369-97. PMID: 22069714; PMCID: PMC3202827.
    18. Richardson RM, Kells AP, Rosenbluth KH, Salegio EA, Fiandaca M, Larson PS, Starr PA, Martin AJ, Lonser RR, Federoff HJ, Forsayeth JR, Bankiewicz KS. Interventional MRI-guided putaminal delivery of AAV2-GDNF for a planned clinical trial in Parkinson's disease. Mol Ther. 2011 Jun; 19(6):1048-57. PMID: 21343917; PMCID: PMC3129792.
    19. Fiandaca M, Salegio EA, Yin D, Richardson RM, Valles FE, Larson PS, Starr PA, Lonser RR, Bankiewicz KS. Human/nonhuman primate AC-PC ratio--considerations for translational brain measurements. J Neurosci Methods. 2011 Mar 15; 196(1):124-30. PMID: 21185868; PMCID: PMC3042049.
    20. Valles F, Fiandaca M, Eberling JL, Starr PA, Larson PS, Christine CW, Forsayeth J, Richardson RM, Su X, Aminoff MJ, Bankiewicz KS. Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment of Parkinson disease. Neurosurgery. 2010 Nov; 67(5):1377-85. PMID: 20871425.
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    21. Fiandaca M, Bankiewicz KS. Gene therapy for Parkinson's disease: from non-human primates to humans. Curr Opin Mol Ther. 2010 Oct; 12(5):519-29. PMID: 20886383.
      View in: PubMed
    22. Yin D, Richardson RM, Fiandaca M, Bringas J, Forsayeth J, Berger MS, Bankiewicz KS. Cannula placement for effective convection-enhanced delivery in the nonhuman primate thalamus and brainstem: implications for clinical delivery of therapeutics. J Neurosurg. 2010 Aug; 113(2):240-8. PMID: 20367078.
      View in: PubMed
    23. Yin D, Valles FE, Fiandaca M, Bringas J, Gimenez F, Berger MS, Forsayeth J, Bankiewicz KS. Optimal region of the putamen for image-guided convection-enhanced delivery of therapeutics in human and non-human primates. Neuroimage. 2011 Jan; 54 Suppl 1:S196-203. PMID: 19761848; PMCID: PMC2895968.
    24. Valles F, Fiandaca M, Bringas J, Dickinson P, LeCouteur R, Higgins R, Berger M, Forsayeth J, Bankiewicz KS. Anatomic compression caused by high-volume convection-enhanced delivery to the brain. Neurosurgery. 2009 Sep; 65(3):579-85; discussion 585-6. PMID: 19687704; PMCID: PMC2745991.
    25. Fiandaca M, Varenika V, Eberling J, McKnight T, Bringas J, Pivirotto P, Beyer J, Hadaczek P, Bowers W, Park J, Federoff H, Forsayeth J, Bankiewicz KS. Real-time MR imaging of adeno-associated viral vector delivery to the primate brain. Neuroimage. 2009 Aug; 47 Suppl 2:T27-35. PMID: 19095069; PMCID: PMC2730220.
    26. Varenika V, Dickinson P, Bringas J, LeCouteur R, Higgins R, Park J, Fiandaca M, Berger M, Sampson J, Bankiewicz K. Detection of infusate leakage in the brain using real-time imaging of convection-enhanced delivery. J Neurosurg. 2008 Nov; 109(5):874-80. PMID: 18976077; PMCID: PMC2725182.
    27. Yin D, Valles FE, Fiandaca M, Forsayeth J, Larson P, Starr P, Bankiewicz KS. Striatal volume differences between non-human and human primates. J Neurosci Methods. 2009 Jan 30; 176(2):200-5. PMID: 18809434; PMCID: PMC2662364.
    28. Fiandaca M, Forsayeth JR, Dickinson PJ, Bankiewicz KS. Image-guided convection-enhanced delivery platform in the treatment of neurological diseases. Neurotherapeutics. 2008 Jan; 5(1):123-7. PMID: 18164491; PMCID: PMC2719019.
    29. Fiandaca M, Forsayeth J, Bankiewicz K. Current status of gene therapy trials for Parkinson's disease. Exp Neurol. 2008 Jan; 209(1):51-7. PMID: 17920059.
      View in: PubMed