-
Elucidating the Oligomerization and Cellular Interactions of a Trimer Derived from Aβ through Fluorescence and Mass Spectrometric Studies. ACS Chem Neurosci. 2022 Aug 17; 13(16):2473-2482.
Guaglianone G, Torrado B, Lin YF, Watkins MC, Wysocki VH, Gratton E, Nowick JS. PMID: 35892278; PMCID: PMC9389591.
View in:
PubMed Mentions: Fields:
-
Enantiomeric β-sheet peptides from Aβ form homochiral pleated β-sheets rather than heterochiral rippled β-sheets. Chem Sci. 2022 Jul 06; 13(26):7739-7746.
Li X, Rios SE, Nowick JS. PMID: 35865901; PMCID: PMC9258340.
View in:
PubMed Mentions:
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Visualizing the mode of action and supramolecular assembly of teixobactin analogues in Bacillus subtilis. Chem Sci. 2022 Jul 06; 13(26):7747-7754.
Morris MA, Vallmitjana A, Grein F, Schneider T, Arts M, Jones CR, Nguyen BT, Hashemian MH, Malek M, Gratton E, Nowick JS. PMID: 35865902; PMCID: PMC9258396.
View in:
PubMed Mentions:
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Editorial. Eur J Med Chem. 2022 06 05; 236:114340.
Moitessier N, Nowick J. PMID: 35405398; PMCID: PMC8970607.
View in:
PubMed Mentions: Fields:
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Effects of Familial Alzheimer's Disease Mutations on the Assembly of a β-Hairpin Peptide Derived from Aβ16-36. Biochemistry. 2022 03 15; 61(6):446-454.
McKnelly KJ, Kreutzer AG, Howitz WJ, Haduong K, Yoo S, Hart C, Nowick JS. PMID: 35213141; PMCID: PMC9042424.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Macrocyclic Peptides Derived from Familial Alzheimer's Disease Mutants Show Charge-Dependent Oligomeric Assembly and Toxicity. ACS Chem Neurosci. 2022 03 16; 13(6):714-720.
Howitz WJ, Guaglianone G, McKnelly KJ, Haduong K, Ashby SN, Laayouni M, Nowick JS. PMID: 35191689; PMCID: PMC9042422.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
A Disulfide-Stabilized Aβ that Forms Dimers but Does Not Form Fibrils. Biochemistry. 2022 02 15; 61(4):252-264.
Zhang S, Yoo S, Snyder DT, Katz BB, Henrickson A, Demeler B, Wysocki VH, Kreutzer AG, Nowick JS. PMID: 35080857; PMCID: PMC9083094.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Synthesis and application of fluorescent teixobactin analogs. Methods Enzymol. 2022; 665:233-258.
Morris MA, Jones CR, Nowick JS. PMID: 35379436; PMCID: PMC9109785.
View in:
PubMed Mentions: Fields:
-
Editorial overview: Amyloid-inspired synthetic biomolecules. Curr Opin Chem Biol. 2021 10; 64:A3-A6.
Petersson EJ, Nowick JS. PMID: 34656424.
View in:
PubMed Mentions: Fields:
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Visualizing Teixobactin Supramolecular Assemblies and Cell Wall Damage in B. Subtilis Using CryoEM. ACS Omega. 2021 Oct 19; 6(41):27412-27417.
Hurst PJ, Morris MA, Graham AA, Nowick JS, Patterson JP. PMID: 34693162; PMCID: PMC8529686.
View in:
PubMed Mentions:
1
-
An Improved Turn Structure for Inducing β-Hairpin Formation in Peptides. Angew Chem Int Ed Engl. 2021 10 11; 60(42):22776-22782.
Li X, Sabol AL, Wierzbicki M, Salveson PJ, Nowick JS. PMID: 34258835; PMCID: PMC8490300.
View in:
PubMed Mentions: Fields:
Translation:
Cells
-
Exploring amyloid oligomers with peptide model systems. Curr Opin Chem Biol. 2021 10; 64:106-115.
Samdin TD, Kreutzer AG, Nowick JS. PMID: 34229162; PMCID: PMC9042423.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Correction to "Expression of N-Terminal Cysteine Aβ42 and Conjugation to Generate Fluorescent and Biotinylated Aβ42". Biochemistry. 2021 Jul 20; 60(28):2272-2273.
Zhang S, Guaglianone G, Morris MA, Yoo S, Howitz WJ, Xing L, Zheng JG, Jusuf H, Huizar G, Lin J, Kreutzer AG, Nowick JS. PMID: 34213906.
View in:
PubMed Mentions: Fields:
-
Synthesis and study of macrocyclic β-hairpin peptides for investigating amyloid oligomers. Methods Enzymol. 2021; 656:123-168.
Guaglianone G, Kreutzer AG, Nowick JS. PMID: 34325785; PMCID: PMC9053554.
View in:
PubMed Mentions: Fields:
-
A cyclic peptide inhibitor of the SARS-CoV-2 main protease. Eur J Med Chem. 2021 Oct 05; 221:113530.
Kreutzer AG, Krumberger M, Diessner EM, Parrocha CMT, Morris MA, Guaglianone G, Butts CT, Nowick JS. PMID: 34023738; PMCID: PMC8096527.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Expression of N-Terminal Cysteine Aβ42 and Conjugation to Generate Fluorescent and Biotinylated Aβ42. Biochemistry. 2021 04 20; 60(15):1191-1200.
Zhang S, Guaglianone G, Morris MA, Yoo S, Howitz WJ, Xing L, Zheng JG, Jusuf H, Huizar G, Lin J, Kreutzer AG, Nowick JS. PMID: 33793198; PMCID: PMC9059633.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Structure-based drug design of an inhibitor of the SARS-CoV-2 (COVID-19) main protease using free software: A tutorial for students and scientists. Eur J Med Chem. 2021 Jun 05; 218:113390.
Zhang S, Krumberger M, Morris MA, Parrocha CMT, Kreutzer AG, Nowick JS. PMID: 33812315; PMCID: PMC7980496.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Phenylalanine Mutation to Cyclohexylalanine Facilitates Triangular Trimer Formation by β-Hairpins Derived from Aβ. J Am Chem Soc. 2020 12 09; 142(49):20708-20716.
Haerianardakani S, Kreutzer AG, Salveson PJ, Samdin TD, Guaglianone GE, Nowick JS. PMID: 33237748; PMCID: PMC7821965.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Correction to "Interpenetrating Cubes in the X-ray Crystallographic Structure of a Peptide Derived from Medin19-36". J Am Chem Soc. 2020 Nov 04; 142(44):18998.
Howitz WJ, Wierzbicki M, Cabanela RW, Saliba C, Motavalli A, Tran N, Nowick JS. PMID: 33086010.
View in:
PubMed Mentions: Fields:
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Interpenetrating Cubes in the X-ray Crystallographic Structure of a Peptide Derived from Medin19-36. J Am Chem Soc. 2020 09 16; 142(37):15870-15875.
Howitz WJ, Wierzbicki M, Cabanela RW, Saliba C, Motavalli A, Tran N, Nowick JS. PMID: 32816461; PMCID: PMC7819122.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Structure-Based Drug Design of an Inhibitor of the SARS-CoV-2 (COVID-19) Main Protease Using Free Software: A Tutorial for Students and Scientists. ChemRxiv. 2020 Aug 12.
Zhang S, Krumberger M, Morris MA, Parrocha CMT, Griffin JH, Kreutzer AG, Nowick JS. PMID: 32817929; PMCID: PMC7430054.
View in:
PubMed Mentions:
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X-ray Crystallography Reveals Parallel and Antiparallel β-Sheet Dimers of a β-Hairpin Derived from Aβ16-36 that Assemble to Form Different Tetramers. ACS Chem Neurosci. 2020 08 05; 11(15):2340-2347.
Kreutzer AG, Samdin TD, Guaglianone G, Spencer RK, Nowick JS. PMID: 32584538; PMCID: PMC7811405.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Effects of N-Terminal Residues on the Assembly of Constrained β-Hairpin Peptides Derived from Aβ. J Am Chem Soc. 2020 07 01; 142(26):11593-11601.
Samdin TD, Wierzbicki M, Kreutzer AG, Howitz WJ, Valenzuela M, Smith A, Sahrai V, Truex NL, Klun M, Nowick JS. PMID: 32501687; PMCID: PMC7927569.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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A Fluorescent Teixobactin Analogue. ACS Chem Biol. 2020 05 15; 15(5):1222-1231.
Morris MA, Malek M, Hashemian MH, Nguyen BT, Manuse S, Lewis K, Nowick JS. PMID: 32045203; PMCID: PMC7814985.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
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Anaphylaxis Induced by Peptide Coupling Agents: Lessons Learned from Repeated Exposure to HATU, HBTU, and HCTU. J Org Chem. 2020 02 07; 85(3):1764-1768.
McKnelly KJ, Sokol W, Nowick JS. PMID: 31849224.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
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Structural Interaction of Apolipoprotein A-I Mimetic Peptide with Amyloid-β Generates Toxic Hetero-oligomers. J Mol Biol. 2020 02 14; 432(4):1020-1034.
Sahoo BR, Bekier ME, Liu Z, Kocman V, Stoddard AK, Anantharamaiah GM, Nowick J, Fierke CA, Wang Y, Ramamoorthy A. PMID: 31866295; PMCID: PMC7054163.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Design, Synthesis, and Study of Lactam and Ring-Expanded Analogues of Teixobactin. J Org Chem. 2020 02 07; 85(3):1331-1339.
Yang H, Pishenko AV, Li X, Nowick JS. PMID: 31746604; PMCID: PMC7814697.
View in:
PubMed Mentions:
2 Fields:
-
Structure-Based Peptide Inhibitor Design of Amyloid-β Aggregation. Front Mol Neurosci. 2019; 12:54.
Lu J, Cao Q, Wang C, Zheng J, Luo F, Xie J, Li Y, Ma X, He L, Eisenberg D, Nowick J, Jiang L, Li D. PMID: 30886570; PMCID: PMC6409328.
View in:
PubMed Mentions:
18
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Structural Polymorphs Suggest Competing Pathways for the Formation of Amyloid Fibrils That Diverge from a Common Intermediate Species. Biochemistry. 2018 11 20; 57(46):6470-6478.
Buchanan LE, Maj M, Dunkelberger EB, Cheng PN, Nowick JS, Zanni MT. PMID: 30375231; PMCID: PMC6368979.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Correction to "Repurposing Triphenylmethane Dyes To Bind to Trimers Derived from Aβ". J Am Chem Soc. 2018 Nov 14; 140(45):15546.
Salveson PJ, Haerianardakani S, Thuy-Boun A, Yoo S, Kreutzer AG, Demeler B, Nowick JS. PMID: 30394740.
View in:
PubMed Mentions: Fields:
-
X-ray Crystallographic Structure of a Teixobactin Derivative Reveals Amyloid-like Assembly. J Am Chem Soc. 2018 10 31; 140(43):14028-14032.
Yang H, Wierzbicki M, Du Bois DR, Nowick JS. PMID: 30296063; PMCID: PMC6356018.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
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Repurposing Triphenylmethane Dyes to Bind to Trimers Derived from Aβ. J Am Chem Soc. 2018 09 19; 140(37):11745-11754.
Salveson PJ, Haerianardakani S, Thuy-Boun A, Yoo S, Kreutzer AG, Demeler B, Nowick JS. PMID: 30125493; PMCID: PMC6339561.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
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An Efficient Method for the Expression and Purification of Aβ(M1-42). Biochemistry. 2018 07 03; 57(26):3861-3866.
Yoo S, Zhang S, Kreutzer AG, Nowick JS. PMID: 29757632; PMCID: PMC6320699.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Controlling the Oligomerization State of Aβ-Derived Peptides with Light. J Am Chem Soc. 2018 05 02; 140(17):5842-5852.
Salveson PJ, Haerianardakani S, Thuy-Boun A, Kreutzer AG, Nowick JS. PMID: 29627987; PMCID: PMC6361387.
View in:
PubMed Mentions:
9 Fields:
-
Elucidating the Structures of Amyloid Oligomers with Macrocyclic β-Hairpin Peptides: Insights into Alzheimer's Disease and Other Amyloid Diseases. Acc Chem Res. 2018 03 20; 51(3):706-718.
Kreutzer AG, Nowick JS. PMID: 29508987; PMCID: PMC5911177.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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A Hexamer of a Peptide Derived from Aβ16-36. Biochemistry. 2017 11 14; 56(45):6061-6071.
Kreutzer AG, Spencer RK, McKnelly KJ, Yoo S, Hamza IL, Salveson PJ, Nowick JS. PMID: 29028351; PMCID: PMC5689071.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Alanine scan reveals modifiable residues in teixobactin. Chem Commun (Camb). 2017 Oct 12; 53(82):11357-11359.
Chen KH, Le SP, Han X, Frias JM, Nowick JS. PMID: 28967925; PMCID: PMC6361391.
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PubMed Mentions:
10 Fields:
-
Effects of charge and hydrophobicity on the oligomerization of peptides derived from IAPP. Bioorg Med Chem. 2018 03 15; 26(6):1151-1156.
Wang Y, Truex NL, Vo NDP, Nowick JS. PMID: 29074350.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Transmembrane Proteins: Amyloids Hidden in Plain Sight? Biochemistry. 2017 09 12; 56(36):4735-4736.
Truex NL, Nowick JS. PMID: 28853555; PMCID: PMC7556710.
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PubMed Mentions: Fields:
Translation:
HumansCells
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A Tetramer Derived from Islet Amyloid Polypeptide. J Org Chem. 2017 08 04; 82(15):7905-7912.
Wang Y, Kreutzer AG, Truex NL, Nowick JS. PMID: 28661686; PMCID: PMC7532939.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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X-ray Crystallographic Structure of a Compact Dodecamer from a Peptide Derived from Aβ16-36. Org Lett. 2017 07 07; 19(13):3462-3465.
Salveson PJ, Spencer RK, Kreutzer AG, Nowick JS. PMID: 28683555; PMCID: PMC5776032.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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X-ray Crystallographic Structure of a Giant Double-Walled Peptide Nanotube Formed by a Macrocyclic β-Sheet Containing Aβ16-22. J Am Chem Soc. 2017 06 21; 139(24):8102-8105.
Chen KH, Corro KA, Le SP, Nowick JS. PMID: 28598147.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
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X-ray crystallographic structure of a teixobactin analogue reveals key interactions of the teixobactin pharmacophore. Chem Commun (Camb). 2017 Feb 28; 53(18):2772-2775.
Yang H, Du Bois DR, Ziller JW, Nowick JS. PMID: 28217800; PMCID: PMC5381722.
View in:
PubMed Mentions:
16 Fields:
Translation:
Cells
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Stabilization, Assembly, and Toxicity of Trimers Derived from Aβ. J Am Chem Soc. 2017 01 18; 139(2):966-975.
Kreutzer AG, Yoo S, Spencer RK, Nowick JS. PMID: 28001392; PMCID: PMC5256483.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Assembly of Peptides Derived from β-Sheet Regions of β-Amyloid. J Am Chem Soc. 2016 10 26; 138(42):13882-13890.
Truex NL, Wang Y, Nowick JS. PMID: 27642651; PMCID: PMC5089065.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
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Coassembly of Peptides Derived from β-Sheet Regions of β-Amyloid. J Am Chem Soc. 2016 10 26; 138(42):13891-13900.
Truex NL, Nowick JS. PMID: 27642763; PMCID: PMC5089069.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
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Square channels formed by a peptide derived from transthyretin. Chem Sci. 2016 Dec 01; 7(12):6946-6951.
Yoo S, Kreutzer AG, Truex NL, Nowick JS. PMID: 28451128; PMCID: PMC5355858.
View in:
PubMed Mentions:
5
-
Elucidation of the Teixobactin Pharmacophore. ACS Chem Biol. 2016 07 15; 11(7):1823-6.
Yang H, Chen KH, Nowick JS. PMID: 27232661; PMCID: PMC5283680.
View in:
PubMed Mentions:
26 Fields:
Translation:
Cells
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X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an Aβ17-36 β-Hairpin. J Am Chem Soc. 2016 Apr 06; 138(13):4634-42.
Kreutzer AG, Hamza IL, Spencer RK, Nowick JS. PMID: 26967810; PMCID: PMC4831588.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
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X-ray Crystallographic Structure of Oligomers Formed by a Toxic β-Hairpin Derived from α-Synuclein: Trimers and Higher-Order Oligomers. J Am Chem Soc. 2016 Apr 06; 138(13):4458-67.
Salveson PJ, Spencer RK, Nowick JS. PMID: 26926877; PMCID: PMC4825732.
View in:
PubMed Mentions:
24 Fields:
Translation:
Cells
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Diversification of β-Augmentation Interactions between CDI Toxin/Immunity Proteins. J Mol Biol. 2015 Nov 20; 427(23):3766-84.
Morse RP, Willett JL, Johnson PM, Zheng J, Credali A, Iniguez A, Nowick JS, Hayes CS, Goulding CW. PMID: 26449640; PMCID: PMC4658667.
View in:
PubMed Mentions:
22 Fields:
Translation:
Cells
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A Newcomer's Guide to Peptide Crystallography. Isr J Chem. 2015 Jun 01; 55(6-7):698-710.
Spencer RK, Nowick JS. PMID: 26213415; PMCID: PMC4508863.
View in:
PubMed Mentions:
13
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X-ray Crystallographic Structures of Oligomers of Peptides Derived from β2-Microglobulin. J Am Chem Soc. 2015 May 20; 137(19):6304-11.
Spencer RK, Kreutzer AG, Salveson PJ, Li H, Nowick JS. PMID: 25915729; PMCID: PMC4523215.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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A fibril-like assembly of oligomers of a peptide derived from β-amyloid. J Am Chem Soc. 2014 Sep 10; 136(36):12682-90.
Pham JD, Spencer RK, Chen KH, Nowick JS. PMID: 25068693; PMCID: PMC4183627.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
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X-ray crystallographic structures of trimers and higher-order oligomeric assemblies of a peptide derived from Aβ(17-36). J Am Chem Soc. 2014 Apr 16; 136(15):5595-8.
Spencer RK, Li H, Nowick JS. PMID: 24669800; PMCID: PMC4004244.
View in:
PubMed Mentions:
47 Fields:
Translation:
Cells
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Polymorphism of oligomers of a peptide from β-amyloid. J Am Chem Soc. 2014 Apr 09; 136(14):5432-42.
Pham JD, Demeler B, Nowick JS. PMID: 24669785; PMCID: PMC4004211.
View in:
PubMed Mentions:
14 Fields:
-
Mechanism of IAPP amyloid fibril formation involves an intermediate with a transient β-sheet. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19285-90.
Buchanan LE, Dunkelberger EB, Tran HQ, Cheng PN, Chiu CC, Cao P, Raleigh DP, de Pablo JJ, Nowick JS, Zanni MT. PMID: 24218609; PMCID: PMC3845187.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansCells
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Structures of oligomers of a peptide from β-amyloid. J Am Chem Soc. 2013 Aug 21; 135(33):12460-7.
Pham JD, Chim N, Goulding CW, Nowick JS. PMID: 23927812; PMCID: PMC3787202.
View in:
PubMed Mentions:
19 Fields:
Translation:
Cells
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A hydrophobic surface is essential to inhibit the aggregation of a tau-protein-derived hexapeptide. J Am Chem Soc. 2013 May 08; 135(18):6846-52.
Zheng J, Baghkhanian AM, Nowick JS. PMID: 23627648.
View in:
PubMed Mentions:
9 Fields:
Translation:
Cells
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The supramolecular chemistry of β-sheets. J Am Chem Soc. 2013 Apr 17; 135(15):5477-92.
Cheng PN, Pham JD, Nowick JS. PMID: 23548073; PMCID: PMC3642101.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):20913-8.
Liu C, Zhao M, Jiang L, Cheng PN, Park J, Sawaya MR, Pensalfini A, Gou D, Berk AJ, Glabe CG, Nowick J, Eisenberg D. PMID: 23213214; PMCID: PMC3529048.
View in:
PubMed Mentions:
86 Fields:
Translation:
HumansCells
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Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity. Nat Chem. 2012 Nov; 4(11):927-33.
Cheng PN, Liu C, Zhao M, Eisenberg D, Nowick JS. PMID: 23089868; PMCID: PMC3481199.
View in:
PubMed Mentions:
70 Fields:
Translation:
HumansAnimalsCells
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Heterodivalent linked macrocyclic β-sheets with enhanced activity against Aβ aggregation: two sites are better than one. J Am Chem Soc. 2012 Aug 29; 134(34):14179-84.
Cheng PN, Spencer R, Woods RJ, Glabe CG, Nowick JS. PMID: 22827298; PMCID: PMC3430741.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Giant macrolactams based on β-sheet peptides. J Org Chem. 2011 May 06; 76(9):3166-73.
Cheng PN, Nowick JS. PMID: 21452877; PMCID: PMC3088102.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
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Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic β-sheet mimics. J Am Chem Soc. 2011 May 04; 133(17):6736-44.
Liu C, Sawaya MR, Cheng PN, Zheng J, Nowick JS, Eisenberg D. PMID: 21473620; PMCID: PMC3124511.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Macrocyclic β-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide. J Am Chem Soc. 2011 Mar 09; 133(9):3144-57.
Zheng J, Liu C, Sawaya MR, Vadla B, Khan S, Woods RJ, Eisenberg D, Goux WJ, Nowick JS. PMID: 21319744; PMCID: PMC3048834.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansCells
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X-ray crystallographic structure of an artificial beta-sheet dimer. J Am Chem Soc. 2010 Aug 25; 132(33):11622-8.
Khakshoor O, Lin AJ, Korman TP, Sawaya MR, Tsai SC, Eisenberg D, Nowick JS. PMID: 20669960; PMCID: PMC2929266.
View in:
PubMed Mentions:
11 Fields:
Translation:
Cells
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Nanometer-scale water-soluble macrocycles from nanometer-sized amino acids. J Org Chem. 2010 Mar 19; 75(6):1822-30.
Gothard CM, Nowick JS. PMID: 20020731; PMCID: PMC2837776.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
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Selective heteronuclear Hartmann-Hahn: a multiple-pulse sequence for selective magnetization transfer in the structural elucidation of "isotagged" oligosaccharides. J Magn Reson. 2010 Mar; 203(1):73-80.
Meng X, Nguyen WH, Nowick JS, Shaka AJ. PMID: 20044287.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Use of disulfide "staples" to stabilize beta-sheet quaternary structure. Org Lett. 2009 Jul 16; 11(14):3000-3.
Khakshoor O, Nowick JS. PMID: 19534505; PMCID: PMC2726807.
View in:
PubMed Mentions:
14 Fields:
Translation:
Cells
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A new artificial beta-sheet that dimerizes through parallel beta-sheet interactions. Org Lett. 2009 Feb 19; 11(4):1003-6.
Levin S, Nowick JS. PMID: 19173616; PMCID: PMC2652689.
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PubMed Mentions:
1 Fields:
Translation:
Cells
-
Functionalized analogues of an unnatural amino acid that mimics a tripeptide beta-strand. Org Lett. 2008 Nov 20; 10(22):5293-6.
Khasanova TV, Khakshoor O, Nowick JS. PMID: 18937484; PMCID: PMC2659333.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
-
Exploring beta-sheet structure and interactions with chemical model systems. Acc Chem Res. 2008 Oct; 41(10):1319-30.
Nowick JS. PMID: 18798654; PMCID: PMC2728010.
View in:
PubMed Mentions:
38 Fields:
Translation:
Cells
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Artificial beta-sheets: chemical models of beta-sheets. Curr Opin Chem Biol. 2008 Dec; 12(6):722-9.
Khakshoor O, Nowick JS. PMID: 18775794; PMCID: PMC2646360.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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An artificial beta-sheet that dimerizes through parallel beta-sheet interactions. J Am Chem Soc. 2007 Oct 31; 129(43):13043-8.
Levin S, Nowick JS. PMID: 17918935; PMCID: PMC2593858.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
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Nanometer-sized amino acids for the synthesis of nanometer-scale water-soluble molecular rods of precise length. J Am Chem Soc. 2007 Jun 13; 129(23):7272-3.
Gothard CM, Rao NA, Nowick JS. PMID: 17503829; PMCID: PMC2552997.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
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Macrocyclic beta-sheet peptides that mimic protein quaternary structure through intermolecular beta-sheet interactions. J Am Chem Soc. 2007 May 02; 129(17):5558-69.
Khakshoor O, Demeler B, Nowick JS. PMID: 17419629; PMCID: PMC2596933.
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PubMed Mentions:
27 Fields:
Translation:
Cells
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Cyclic modular beta-sheets. J Am Chem Soc. 2007 Mar 07; 129(9):2548-58.
Woods RJ, Brower JO, Castellanos E, Hashemzadeh M, Khakshoor O, Russu WA, Nowick JS. PMID: 17295482; PMCID: PMC2597679.
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PubMed Mentions:
21 Fields:
Translation:
Cells
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A new class of macrocyclic receptors from iota-peptides. J Am Chem Soc. 2007 Feb 14; 129(6):1486-7.
Kang SW, Gothard CM, Maitra S, Nowick JS. PMID: 17243690.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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What I have learned by using chemical model systems to study biomolecular structure and interactions. Org Biomol Chem. 2006 Nov 07; 4(21):3869-85.
Nowick JS. PMID: 17047863.
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PubMed Mentions:
13 Fields:
Translation:
Cells
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The absence of favorable aromatic interactions between beta-sheet peptides. J Am Chem Soc. 2005 Jul 20; 127(28):9998-9.
Chung DM, Dou Y, Baldi P, Nowick JS. PMID: 16011353.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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ICBS: a database of interactions between protein chains mediated by beta-sheet formation. Bioinformatics. 2004 Nov 01; 20(16):2767-77.
Dou Y, Baisnée PF, Pollastri G, Pécout Y, Nowick J, Baldi P. PMID: 15166020.
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PubMed Mentions:
19 Fields:
Translation:
Cells
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Enantioselective molecular recognition between beta-sheets. J Am Chem Soc. 2004 Mar 17; 126(10):3062-3.
Chung DM, Nowick JS. PMID: 15012131.
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PubMed Mentions:
17 Fields:
Translation:
Cells
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DSA: a new internal standard for NMR studies in aqueous solution. Org Lett. 2003 Sep 18; 5(19):3511-3.
Nowick JS, Khakshoor O, Hashemzadeh M, Brower JO. PMID: 12967312.
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PubMed Mentions:
18 Fields:
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Sequence-selective molecular recognition between beta sheets. Angew Chem Int Ed Engl. 2003 Apr 17; 42(15):1765-8.
Nowick JS, Chung DM. PMID: 12707901.
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PubMed Mentions:
9 Fields:
Translation:
Cells
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Dityrosine cross-linked Abeta peptides: fibrillar beta-structure in Abeta(1-40) is conducive to formation of dityrosine cross-links but a dityrosine cross-link in Abeta(8-14) does not induce beta-structure. Chem Res Toxicol. 2003 Apr; 16(4):531-5.
Yoburn JC, Tian W, Brower JO, Nowick JS, Glabe CG, Van Vranken DL. PMID: 12703970.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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A new turn structure for the formation of beta-hairpins in peptides. J Am Chem Soc. 2003 Jan 29; 125(4):876-7.
Nowick JS, Brower JO. PMID: 12537479.
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PubMed Mentions:
41 Fields:
Translation:
Cells
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A ribozyme with michaelase activity: synthesis of the substrate precursors. Bioorg Med Chem. 2003 Jan 17; 11(2):235-49.
Eisenführ A, Arora PS, Sengle G, Takaoka LR, Nowick JS, Famulok M. PMID: 12470718.
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PubMed Mentions:
8 Fields:
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Methylglyoxal synthetase, enol-pyruvaldehyde, glutathione and the glyoxalase system. J Am Chem Soc. 2002 Nov 06; 124(44):13047-52.
Rose IA, Nowick JS. PMID: 12405831.
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PubMed Mentions:
4 Fields:
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An unnatural amino acid that induces beta-sheet folding and interaction in peptides. J Am Chem Soc. 2002 May 08; 124(18):4972-3.
Nowick JS, Lam KS, Khasanova TV, Kemnitzer WE, Maitra S, Mee HT, Liu R. PMID: 11982357.
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PubMed Mentions:
21 Fields:
Translation:
Cells
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A triply templated artificial beta-sheet. J Am Chem Soc. 2001 Jun 06; 123(22):5176-80.
Nowick JS, Cary JM, Tsai JH. PMID: 11457378.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Novel RNA catalysts for the Michael reaction. Chem Biol. 2001 May; 8(5):459-73.
Sengle G, Eisenführ A, Arora PS, Nowick JS, Famulok M. PMID: 11358693.
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PubMed Mentions:
21 Fields:
Translation:
Cells
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Fmoc: a more soluble analogue of the 9-fluorenylmethoxycarbonyl protecting group. J Org Chem. 2000 Jun 16; 65(12):3858-60.
Stigers KD, Koutroulis MR, Chung DM, Nowick JS. PMID: 10864776.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Synthesis, incorporation efficiency, and stability of disulfide bridged functional groups at RNA 5'-ends. Bioorg Med Chem. 2000 Jun; 8(6):1317-29.
Sengle G, Jenne A, Arora PS, Seelig B, Nowick JS, Jäschke A, Famulok M. PMID: 10896110.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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Designed molecules that fold to mimic protein secondary structures. Curr Opin Chem Biol. 1999 Dec; 3(6):714-23.
Stigers KD, Soth MJ, Nowick JS. PMID: 10600726.
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PubMed Mentions:
17 Fields:
Translation:
Cells
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A Peptide/Oligourea/Azapeptide Hybrid That Adopts a Hairpin Turn. J Org Chem. 1999 Jan 08; 64(1):276-281.
Soth MJ, Nowick JS. PMID: 11674113.
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PubMed Mentions:
2 Fields:
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Two new beta-strand mimics. Bioorg Med Chem. 1999 Jan; 7(1):29-38.
Tsai JH, Waldman AS, Nowick JS. PMID: 10199654.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Design and synthesis of a transition state analogue for the Diels-Alder reaction. Bioorg Med Chem. 1998 Sep; 6(9):1421-8.
Arora PS, Van QN, Famulok M, Shaka AJ, Nowick JS. PMID: 9801813.
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PubMed Mentions: Fields:
Translation:
Cells
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An Artificial Antiparallel beta-Sheet Containing a New Peptidomimetic Template. J Org Chem. 1997 Nov 14; 62(23):7906-7907.
Smith EM, Holmes DL, Shaka AJ, Nowick JS. PMID: 11671886.
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PubMed Mentions:
2 Fields:
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Unnatural oligomers and unnatural oligomer libraries. Curr Opin Chem Biol. 1997 Jun; 1(1):120-9.
Soth MJ, Nowick JS. PMID: 9667839.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Synthesis of Peptide Isocyanates and Isothiocyanates. J Org Chem. 1996 May 31; 61(11):3929-3934.
Nowick JS, Holmes DL, Noronha G, Smith EM, Nguyen TM, Huang SL. PMID: 11667260.
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PubMed Mentions:
9 Fields:
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Molecular Recognition between Uncharged Molecules in Aqueous Micelles. J Am Chem Soc. 1994 Apr 01; 116(8):3285-9.
Nowick JS, Cao T, Noronha G. PMID: 25084234.
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PubMed Mentions:
5 Fields:
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Self-replicating systems. Acta Chem Scand. 1992 Apr; 46(4):315-24.
Famulok M, Nowick JS, Rebek J. PMID: 1381212.
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PubMed Mentions:
1 Fields:
Translation:
Cells