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James G Jakowatz

Title(s)Health Sciences Professor, Surgery
Phone(714) 456-8000
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Yuan TA, Lu Y, Edwards K, Jakowatz J, Meyskens FL, Liu-Smith F. Race-, Age-, and Anatomic Site-Specific Gender Differences in Cutaneous Melanoma Suggest Differential Mechanisms of Early- and Late-Onset Melanoma. Int J Environ Res Public Health. 2019 03 13; 16(6). PMID: 30871230.
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    2. Fruehauf JP, El-Masry M, Osann K, Parmakhtiar B, Yamamoto M, Jakowatz JG. Phase II study of pazopanib in combination with paclitaxel in patients with metastatic melanoma. Cancer Chemother Pharmacol. 2018 08; 82(2):353-360. PMID: 29943192.
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    3. Yue L, Huang ZM, Fong S, Leong S, Jakowatz JG, Charruyer-Reinwald A, Wei M, Ghadially R. Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma. Melanoma Res. 2015 Apr; 25(2):138-48. PMID: 25643237.
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    4. Linden KG, Leachman SA, Zager JS, Jakowatz JG, Viner JL, McLaren CE, Barr RJ, Carpenter PM, Chen WP, Elmets CA, Tangrea JA, Lim SJ, Cochran AJ, Meyskens FL. A randomized, double-blind, placebo-controlled phase II clinical trial of lovastatin for various endpoints of melanoma pathobiology. Cancer Prev Res (Phila). 2014 May; 7(5):496-504. PMID: 24614012.
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    5. Eroglu Z, Kong KM, Jakowatz JG, Samlowski W, Fruehauf JP. Phase II clinical trial evaluating docetaxel, vinorelbine and GM-CSF in stage IV melanoma. Cancer Chemother Pharmacol. 2011 Oct; 68(4):1081-7. PMID: 21769667.
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    6. Lane K, Kempf A, Magno C, Lane J, Butler J, Hsiang D, Greenfield S, Jakowatz J. Regional differences in the use of sentinel lymph node biopsy for melanoma: a potential quality measure. Am Surg. 2008 Oct; 74(10):981-4. PMID: 18942627.
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    7. Mitchell MS, Abrams J, Thompson JA, Kashani-Sabet M, DeConti RC, Hwu WJ, Atkins MB, Whitman E, Ernstoff MS, Haluska FG, Jakowatz JG, Das Gupta TK, Richards JM, Samlowski WE, Costanzi JJ, Aronson FR, Deisseroth AB, Dudek AZ, Jones VE. Randomized trial of an allogeneic melanoma lysate vaccine with low-dose interferon Alfa-2b compared with high-dose interferon Alfa-2b for Resected stage III cutaneous melanoma. J Clin Oncol. 2007 May 20; 25(15):2078-85. PMID: 17513813.
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    8. Wong SF, Jakowatz JG, Taheri R. Potential drug-drug interaction between interferon alfa-2b and gemfibrozil in a patient with malignant melanoma. Clin Ther. 2005 Dec; 27(12):1942-8. PMID: 16507380.
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    9. Fruehauf JP, Kong KM, Jakowatz JG. Docetaxel and vinorelbine plus GM-CSF in malignant melanoma. Oncology (Williston Park). 2005 Apr; 19(4 Suppl 2):19-22. PMID: 15934496.
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    10. Wong SF, Jakowatz JG, Taheri R. Management of hypertriglyceridemia in patients receiving interferon for malignant melanoma. Ann Pharmacother. 2004 Oct; 38(10):1655-9. PMID: 15304625.
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    11. Cole MD, Jakowatz J, Evans GR. Evaluation of nodal patterns for melanoma of the ear. Plast Reconstr Surg. 2003 Jul; 112(1):50-6. PMID: 12832876.
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    12. Chorny JA, Barr RJ, Kyshtoobayeva A, Jakowatz J, Reed RJ. Ki-67 and p53 expression in minimal deviation melanomas as compared with other nevomelanocytic lesions. Mod Pathol. 2003 Jun; 16(6):525-9. PMID: 12808056.
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    13. Badgwell BD, Valentino DJ, Jeffes EB, Dieffenbach K, Dulkanchainun SB, Yamamoto RS, Granger GA, Jakowatz JG, Carson WE. Intra-arterial administration of TNF-alpha followed by arterial ablation is an effective therapy for a regionally confined TNF-resistant rat mammary adenocarcinoma. Cancer Immunol Immunother. 2003 Jan; 52(1):10-6. PMID: 12536235.
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    14. Podnos YD, Jimenez JC, Zainabadi K, Jakowatz JG, Barr RJ. Minimal deviation melanoma. Cancer Treat Rev. 2002 Oct; 28(5):219-21. PMID: 12435369.
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    15. Sondak VK, Liu PY, Tuthill RJ, Kempf RA, Unger JM, Sosman JA, Thompson JA, Weiss GR, Redman BG, Jakowatz JG, Noyes RD, Flaherty LE. Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: overall results of a randomized trial of the Southwest Oncology Group. J Clin Oncol. 2002 Apr 15; 20(8):2058-66. PMID: 11956266.
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    16. Grant SW, Kyshtoobayeva AS, Kurosaki T, Jakowatz J, Fruehauf JP. Mutant p53 correlates with reduced expression of thrombospondin-1, increased angiogenesis, and metastatic progression in melanoma. Cancer Detect Prev. 1998; 22(3):185-94. PMID: 9618039.
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    17. Jakowatz JG, Meyskens FL. Evaluation and treatment of the patient with early melanoma. Compr Ther. 1995; 21(1):46-50. PMID: 7697982.
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    18. Mitchell MS, Jakowatz J, Harel W, Dean G, Stevenson L, Boswell WD, Groshen S. Increased effectiveness of interferon alfa-2b following active specific immunotherapy for melanoma. J Clin Oncol. 1994 Feb; 12(2):402-11. PMID: 8113848.
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    19. Wuerker RB, Gordon IL, Jakowatz JG. Characteristics of cancer cells in gastrointestinal lavage specimens. Acta Cytol. 1993 May-Jun; 37(3):379-84. PMID: 8498139.
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    20. Hourani LL, Jakowatz J, Goodman M, Mueller G, Brodie G, Jaffery A. Concordance of hospital cancer registry- and physician-collected data for patients with melanoma. J Natl Cancer Inst. 1992 Nov 18; 84(22):1749-50. PMID: 1433360.
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    21. Sarfeh IJ, Jakowatz JG. Surgical treatment of enteric 'bud' fistulas in contaminated wounds. A riskless extraperitoneal method using split-thickness skin grafts. Arch Surg. 1992 Sep; 127(9):1027-30; discussion 1030-1. PMID: 1387525.
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    22. Waki EY, Crumley RL, Jakowatz JG. Effects of pharmacologic agents on human keloids implanted in athymic mice. A pilot study. Arch Otolaryngol Head Neck Surg. 1991 Oct; 117(10):1177-81. PMID: 1910708.
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    23. Liu SK, Jakowatz JG, Pollack RB, Ceraldi C, Yamamoto R, Dett C, Lopez F, Camacho C, Carson WE, Sentovich SM. Effects of intracarotid and intravenous infusion of human TNF and LT on established intracerebral rat gliomas. Lymphokine Cytokine Res. 1991 Jun; 10(3):189-94. PMID: 1883913.
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    24. Jakowatz JG, Ginn GE, Snyder LM, Dieffenbach KW, Wile AG. Increased cisplatin tissue levels with prolonged arterial infusion in the rat. Cancer. 1991 Jun 01; 67(11):2828-32. PMID: 2025848.
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    25. Carson WE, Jakowatz JG, Yamamoto R, Fitzgerald T, Gupta S, Vayuvegula B, Lucci JA, Beckman MT, Dulkanchainun S, Granger GA. Rat mitogen-stimulated lymphokine-activated T killer cells: production and effects on C6 glioma cells in vitro and in vivo in the brain of Wistar rats. J Immunother (1991). 1991 Apr; 10(2):131-40. PMID: 2043593.
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    26. Yamamoto RS, Coss J, Vayuvegula B, Gupta S, Beamer Y, Jacques S, Jeffes EW, Carson WE, Jakowatz J, Granger GA. Generation of stimulated, lymphokine activated T killer (T-LAK) cells from the peripheral blood of normal donors and adult patients with recurrent glioblastoma. J Immunol Methods. 1991 Mar 21; 137(2):225-35. PMID: 2013699.
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    27. Jakowatz JG, Gan K, Ulich TR, Wile AG. Murine monoclonal antibodies to human pancreatic cancer: specificity and sensitivity. Oncology. 1990; 47(2):149-54. PMID: 2314827.
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    28. Sarfeh IJ, Rypins EB, Jakowatz JG, Juler GL. A prospective, randomized clinical investigation of cholecystoenterostomy and choledochoenterostomy. Am J Surg. 1988 Mar; 155(3):411-4. PMID: 3278638.
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    29. Tenzer JA, Rypins RD, Jakowatz JG. Malignant cystosarcoma phyllodes metastatic to the maxilla. J Oral Maxillofac Surg. 1988 Jan; 46(1):80-2. PMID: 2828585.
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    30. Wile AG, Kar R, Cohen RA, Jakowatz JG, Opfell RW. The pharmacokinetics of cisplatin in experimental regional chemotherapy. Cancer. 1987 Feb 15; 59(4):695-700. PMID: 3802029.
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    31. Philben VJ, Jakowatz JG, Beatty BG, Vlahos WG, Paxton RJ, Williams LE, Shively JE, Beatty JD. The effect of tumor CEA content and tumor size on tissue uptake of indium 111-labeled anti-CEA monoclonal antibody. Cancer. 1986 Feb 01; 57(3):571-6. PMID: 3942992.
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    32. Jakowatz JG, Porudominsky D, Riihimaki DU, Kemeny M, Kokal WA, Braly PS, Terz JJ, Beatty JD. Complications of pelvic exenteration. Arch Surg. 1985 Nov; 120(11):1261-5. PMID: 4051730.
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    33. Jakowatz JG, Beatty BG, Vlahos WG, Porudominsky D, Philben VJ, Williams LE, Paxton RJ, Shively JE, Beatty JD. High-specific-activity 111In-labeled anticarcinoembryonic antigen monoclonal antibody: biodistribution and imaging in nude mice bearing human colon cancer xenografts. Cancer Res. 1985 Nov; 45(11 Pt 2):5700-6. PMID: 4053043.
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    34. Paxton RJ, Jakowatz JG, Beatty JD, Beatty BG, Vlahos WG, Williams LE, Clark BR, Shively JE. High-specific-activity 111In-labeled anticarcinoembryonic antigen monoclonal antibody: improved method for the synthesis of diethylenetriaminepentaacetic acid conjugates. Cancer Res. 1985 Nov; 45(11 Pt 2):5694-9. PMID: 4053042.
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    35. Deziel DJ, Jakowatz JG, Stibolt TB, Roseman DL. The frequency response of the canine choledochoduodenal junction. Curr Surg. 1984 Mar-Apr; 41(2):94-7. PMID: 6723360.
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