James G Jakowatz

Title(s)Health Sciences Professor, Surgery
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-8000
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Impact of Immediate Surgical Reconstruction Following Wide Local Excision of Malignant Head and Neck Melanoma. Plast Reconstr Surg Glob Open. 2020 Feb; 8(2):e2661. Hu AC, Lee SA, Clark EG, Yamamoto M, Jakowatz JG, Evans GRD. PMID: 32309102.
      View in: PubMed   Mentions:
    2. Race-, Age-, and Anatomic Site-Specific Gender Differences in Cutaneous Melanoma Suggest Differential Mechanisms of Early- and Late-Onset Melanoma. Int J Environ Res Public Health. 2019 03 13; 16(6). Yuan TA, Lu Y, Edwards K, Jakowatz J, Meyskens FL, Liu-Smith F. PMID: 30871230.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Phase II study of pazopanib in combination with paclitaxel in patients with metastatic melanoma. Cancer Chemother Pharmacol. 2018 08; 82(2):353-360. Fruehauf JP, El-Masry M, Osann K, Parmakhtiar B, Yamamoto M, Jakowatz JG. PMID: 29943192.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    4. Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma. Melanoma Res. 2015 Apr; 25(2):138-48. Yue L, Huang ZM, Fong S, Leong S, Jakowatz JG, Charruyer-Reinwald A, Wei M, Ghadially R. PMID: 25643237.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    5. A randomized, double-blind, placebo-controlled phase II clinical trial of lovastatin for various endpoints of melanoma pathobiology. Cancer Prev Res (Phila). 2014 May; 7(5):496-504. Linden KG, Leachman SA, Zager JS, Jakowatz JG, Viner JL, McLaren CE, Barr RJ, Carpenter PM, Chen WP, Elmets CA, Tangrea JA, Lim SJ, Cochran AJ, Meyskens FL. PMID: 24614012.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    6. Phase II clinical trial evaluating docetaxel, vinorelbine and GM-CSF in stage IV melanoma. Cancer Chemother Pharmacol. 2011 Oct; 68(4):1081-7. Eroglu Z, Kong KM, Jakowatz JG, Samlowski W, Fruehauf JP. PMID: 21769667.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    7. Regional differences in the use of sentinel lymph node biopsy for melanoma: a potential quality measure. Am Surg. 2008 Oct; 74(10):981-4. Lane K, Kempf A, Magno C, Lane J, Butler J, Hsiang D, Greenfield S, Jakowatz J. PMID: 18942627.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    8. Randomized trial of an allogeneic melanoma lysate vaccine with low-dose interferon Alfa-2b compared with high-dose interferon Alfa-2b for Resected stage III cutaneous melanoma. J Clin Oncol. 2007 May 20; 25(15):2078-85. Mitchell MS, Abrams J, Thompson JA, Kashani-Sabet M, DeConti RC, Hwu WJ, Atkins MB, Whitman E, Ernstoff MS, Haluska FG, Jakowatz JG, Das Gupta TK, Richards JM, Samlowski WE, Costanzi JJ, Aronson FR, Deisseroth AB, Dudek AZ, Jones VE. PMID: 17513813.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    9. Potential drug-drug interaction between interferon alfa-2b and gemfibrozil in a patient with malignant melanoma. Clin Ther. 2005 Dec; 27(12):1942-8. Wong SF, Jakowatz JG, Taheri R. PMID: 16507380.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Docetaxel and vinorelbine plus GM-CSF in malignant melanoma. Oncology (Williston Park). 2005 Apr; 19(4 Suppl 2):19-22. Fruehauf JP, Kong KM, Jakowatz JG. PMID: 15934496.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    11. Management of hypertriglyceridemia in patients receiving interferon for malignant melanoma. Ann Pharmacother. 2004 Oct; 38(10):1655-9. Wong SF, Jakowatz JG, Taheri R. PMID: 15304625.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Evaluation of nodal patterns for melanoma of the ear. Plast Reconstr Surg. 2003 Jul; 112(1):50-6. Cole MD, Jakowatz J, Evans GR. PMID: 12832876.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Ki-67 and p53 expression in minimal deviation melanomas as compared with other nevomelanocytic lesions. Mod Pathol. 2003 Jun; 16(6):525-9. Chorny JA, Barr RJ, Kyshtoobayeva A, Jakowatz J, Reed RJ. PMID: 12808056.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    14. Intra-arterial administration of TNF-alpha followed by arterial ablation is an effective therapy for a regionally confined TNF-resistant rat mammary adenocarcinoma. Cancer Immunol Immunother. 2003 Jan; 52(1):10-6. Badgwell BD, Valentino DJ, Jeffes EB, Dieffenbach K, Dulkanchainun SB, Yamamoto RS, Granger GA, Jakowatz JG, Carson WE. PMID: 12536235.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    15. Minimal deviation melanoma. Cancer Treat Rev. 2002 Oct; 28(5):219-21. Podnos YD, Jimenez JC, Zainabadi K, Jakowatz JG, Barr RJ. PMID: 12435369.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: overall results of a randomized trial of the Southwest Oncology Group. J Clin Oncol. 2002 Apr 15; 20(8):2058-66. Sondak VK, Liu PY, Tuthill RJ, Kempf RA, Unger JM, Sosman JA, Thompson JA, Weiss GR, Redman BG, Jakowatz JG, Noyes RD, Flaherty LE. PMID: 11956266.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCTClinical Trials
    17. Mutant p53 correlates with reduced expression of thrombospondin-1, increased angiogenesis, and metastatic progression in melanoma. Cancer Detect Prev. 1998; 22(3):185-94. Grant SW, Kyshtoobayeva AS, Kurosaki T, Jakowatz J, Fruehauf JP. PMID: 9618039.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    18. Evaluation and treatment of the patient with early melanoma. Compr Ther. 1995; 21(1):46-50. Jakowatz JG, Meyskens FL. PMID: 7697982.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Increased effectiveness of interferon alfa-2b following active specific immunotherapy for melanoma. J Clin Oncol. 1994 Feb; 12(2):402-11. Mitchell MS, Jakowatz J, Harel W, Dean G, Stevenson L, Boswell WD, Groshen S. PMID: 8113848.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Characteristics of cancer cells in gastrointestinal lavage specimens. Acta Cytol. 1993 May-Jun; 37(3):379-84. Wuerker RB, Gordon IL, Jakowatz JG. PMID: 8498139.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    21. Concordance of hospital cancer registry- and physician-collected data for patients with melanoma. J Natl Cancer Inst. 1992 Nov 18; 84(22):1749-50. Hourani LL, Jakowatz J, Goodman M, Mueller G, Brodie G, Jaffery A. PMID: 1433360.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Surgical treatment of enteric 'bud' fistulas in contaminated wounds. A riskless extraperitoneal method using split-thickness skin grafts. Arch Surg. 1992 Sep; 127(9):1027-30; discussion 1030-1. Sarfeh IJ, Jakowatz JG. PMID: 1387525.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. Effects of pharmacologic agents on human keloids implanted in athymic mice. A pilot study. Arch Otolaryngol Head Neck Surg. 1991 Oct; 117(10):1177-81. Waki EY, Crumley RL, Jakowatz JG. PMID: 1910708.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    24. Increased cisplatin tissue levels with prolonged arterial infusion in the rat. Cancer. 1991 Jun 01; 67(11):2828-32. Jakowatz JG, Ginn GE, Snyder LM, Dieffenbach KW, Wile AG. PMID: 2025848.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    25. Effects of intracarotid and intravenous infusion of human TNF and LT on established intracerebral rat gliomas. Lymphokine Cytokine Res. 1991 Jun; 10(3):189-94. Liu SK, Jakowatz JG, Pollack RB, Ceraldi C, Yamamoto R, Dett C, Lopez F, Camacho C, Carson WE, Sentovich SM. PMID: 1883913.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    26. Rat mitogen-stimulated lymphokine-activated T killer cells: production and effects on C6 glioma cells in vitro and in vivo in the brain of Wistar rats. J Immunother (1991). 1991 Apr; 10(2):131-40. Carson WE, Jakowatz JG, Yamamoto R, Fitzgerald T, Gupta S, Vayuvegula B, Lucci JA, Beckman MT, Dulkanchainun S, Granger GA. PMID: 2043593.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    27. Generation of stimulated, lymphokine activated T killer (T-LAK) cells from the peripheral blood of normal donors and adult patients with recurrent glioblastoma. J Immunol Methods. 1991 Mar 21; 137(2):225-35. Yamamoto RS, Coss J, Vayuvegula B, Gupta S, Beamer Y, Jacques S, Jeffes EW, Carson WE, Jakowatz J, Granger GA. PMID: 2013699.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    28. Murine monoclonal antibodies to human pancreatic cancer: specificity and sensitivity. Oncology. 1990; 47(2):149-54. Jakowatz JG, Gan K, Ulich TR, Wile AG. PMID: 2314827.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    29. A prospective, randomized clinical investigation of cholecystoenterostomy and choledochoenterostomy. Am J Surg. 1988 Mar; 155(3):411-4. Sarfeh IJ, Rypins EB, Jakowatz JG, Juler GL. PMID: 3278638.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCTClinical Trials
    30. Malignant cystosarcoma phyllodes metastatic to the maxilla. J Oral Maxillofac Surg. 1988 Jan; 46(1):80-2. Tenzer JA, Rypins RD, Jakowatz JG. PMID: 2828585.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. The pharmacokinetics of cisplatin in experimental regional chemotherapy. Cancer. 1987 Feb 15; 59(4):695-700. Wile AG, Kar R, Cohen RA, Jakowatz JG, Opfell RW. PMID: 3802029.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    32. The effect of tumor CEA content and tumor size on tissue uptake of indium 111-labeled anti-CEA monoclonal antibody. Cancer. 1986 Feb 01; 57(3):571-6. Philben VJ, Jakowatz JG, Beatty BG, Vlahos WG, Paxton RJ, Williams LE, Shively JE, Beatty JD. PMID: 3942992.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    33. Complications of pelvic exenteration. Arch Surg. 1985 Nov; 120(11):1261-5. Jakowatz JG, Porudominsky D, Riihimaki DU, Kemeny M, Kokal WA, Braly PS, Terz JJ, Beatty JD. PMID: 4051730.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    34. High-specific-activity 111In-labeled anticarcinoembryonic antigen monoclonal antibody: improved method for the synthesis of diethylenetriaminepentaacetic acid conjugates. Cancer Res. 1985 Nov; 45(11 Pt 2):5694-9. Paxton RJ, Jakowatz JG, Beatty JD, Beatty BG, Vlahos WG, Williams LE, Clark BR, Shively JE. PMID: 4053042.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    35. High-specific-activity 111In-labeled anticarcinoembryonic antigen monoclonal antibody: biodistribution and imaging in nude mice bearing human colon cancer xenografts. Cancer Res. 1985 Nov; 45(11 Pt 2):5700-6. Jakowatz JG, Beatty BG, Vlahos WG, Porudominsky D, Philben VJ, Williams LE, Paxton RJ, Shively JE, Beatty JD. PMID: 4053043.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    36. The frequency response of the canine choledochoduodenal junction. Curr Surg. 1984 Mar-Apr; 41(2):94-7. Deziel DJ, Jakowatz JG, Stibolt TB, Roseman DL. PMID: 6723360.
      View in: PubMed   Mentions:    Fields:    Translation:Animals