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Jack J Lin

Title(s)Clinical Professor, Neurology
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-6203 (949) 824
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    Early-onset epilepsy and genetics influence white matter tracts and cognition
    NIH/NINDS K23NS060993Aug 1, 2009 - Jul 31, 2014
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Amplitude of high frequency oscillations as a biomarker of the seizure onset zone. Clin Neurophysiol. 2020 Aug 25; 131(11):2542-2550. Charupanit K, Sen-Gupta I, Lin JJ, Lopour BA. PMID: 32927209.
      View in: PubMed   Mentions:    Fields:    
    2. An electrophysiological marker of arousal level in humans. Elife. 2020 07 28; 9. Lendner JD, Helfrich RF, Mander BA, Romundstad L, Lin JJ, Walker MP, Larsson PG, Knight RT. PMID: 32720644.
      View in: PubMed   Mentions:    Fields:    
    3. The Effect of BMI on Internal Rotation and Function Following Anatomic and Reverse Total Shoulder Arthroplasty. J Shoulder Elbow Surg. 2020 Jun 30. Eichinger JK, Rao MV, Lin JJ, Goodloe JB, Kothandaraman V, Barfield WR, Parada SA, Roche C, Friedman RJ. PMID: 32619658.
      View in: PubMed   Mentions:    Fields:    
    4. Shoulder motion decreases as body mass increases in patients with asymptomatic shoulders. JSES Int. 2020 Sep; 4(3):438-442. Allen WE, Lin JJ, Barfield WB, Friedman RJ, Eichinger JK. PMID: 32939465.
      View in: PubMed   Mentions:
    5. A Novel Robotic-Assisted Technique to Implant the Responsive Neurostimulation System. Oper Neurosurg (Hagerstown). 2020 Jun 01; 18(6):728-735. Tran DK, Paff M, Mnatsakanyan L, Sen-Gupta I, Lin JJ, Hsu FPK, Vadera S. PMID: 31538187.
      View in: PubMed   Mentions:    Fields:    
    6. Detection of anomalous high-frequency events in human intracranial EEG. Epilepsia Open. 2020 Jun; 5(2):263-273. Charupanit K, Sen-Gupta I, Lin JJ, Lopour BA. PMID: 32524052.
      View in: PubMed   Mentions:
    7. Pitch count adherence and injury assessment of youth baseball in South Carolina. J Orthop. 2020 Sep-Oct; 21:62-68. Eichinger JK, Goodloe JB, Lin JJ, Greenhouse A, Rao MV, Friedman RJ, Roberts JR. PMID: 32123489.
      View in: PubMed   Mentions:
    8. The Effect of Screw Design and Cortical Augmentation on Insertional Torque and Compression in Coracoid-Glenoid Fixation in a Sawbones Model. Arthroscopy. 2020 03; 36(3):689-695. Rabinowitz J, Lin JJ, Greenhouse A, Rao MV, Provencher M, Parada S, Friedman RJ, Eichinger JK. PMID: 31901392.
      View in: PubMed   Mentions:    Fields:    
    9. Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nat Commun. 2019 09 19; 10(1):4275. Juvvadi PR, Fox D, Bobay BG, Hoy MJ, Gobeil SMC, Venters RA, Chang Z, Lin JJ, Averette AF, Cole DC, Barrington BC, Wheaton JD, Ciofani M, Trzoss M, Li X, Lee SC, Chen YL, Mutz M, Spicer LD, Schumacher MA, Heitman J, Steinbach WJ. PMID: 31537789.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    10. Default network and frontoparietal control network theta connectivity supports internal attention. Nat Hum Behav. 2019 12; 3(12):1263-1270. Kam JWY, Lin JJ, Solbakk AK, Endestad T, Larsson PG, Knight RT. PMID: 31477910.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    11. Bidirectional prefrontal-hippocampal dynamics organize information transfer during sleep in humans. Nat Commun. 2019 08 08; 10(1):3572. Helfrich RF, Lendner JD, Mander BA, Guillen H, Paff M, Mnatsakanyan L, Vadera S, Walker MP, Lin JJ, Knight RT. PMID: 31395890.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Network analysis of prospective brain development in youth with benign epilepsy with centrotemporal spikes and its relationship to cognition. Epilepsia. 2019 09; 60(9):1838-1848. Garcia-Ramos C, Dabbs K, Lin JJ, Jones JE, Stafstrom CE, Hsu DA, Meyerand ME, Prabhakaran V, Hermann BP. PMID: 31347155.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Multiplexing of Theta and Alpha Rhythms in the Amygdala-Hippocampal Circuit Supports Pattern Separation of Emotional Information. Neuron. 2019 05 22; 102(4):887-898.e5. Zheng J, Stevenson RF, Mander BA, Mnatsakanyan L, Hsu FPK, Vadera S, Knight RT, Yassa MA, Lin JJ. PMID: 30979537.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. Editorial for the special issue on language and epilepsy. Brain Lang. 2019 06; 193:1-3. Bonilha L, Small SS, Lin JJ. PMID: 30929763.
      View in: PubMed   Mentions:    Fields:    
    15. Medial Orbitofrontal Cortex, Dorsolateral Prefrontal Cortex, and Hippocampus Differentially Represent the Event Saliency. J Cogn Neurosci. 2019 06; 31(6):874-884. Jafarpour A, Griffin S, Lin JJ, Knight RT. PMID: 30883290.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Spectral Imprints of Working Memory for Everyday Associations in the Frontoparietal Network. Front Syst Neurosci. 2018; 12:65. Johnson EL, King-Stephens D, Weber PB, Laxer KD, Lin JJ, Knight RT. PMID: 30670953.
      View in: PubMed   Mentions:
    17. Temporal Dynamics and Response Modulation across the Human Visual System in a Spatial Attention Task: An ECoG Study. J Neurosci. 2019 01 09; 39(2):333-352. Martin AB, Yang X, Saalmann YB, Wang L, Shestyuk A, Lin JJ, Parvizi J, Knight RT, Kastner S. PMID: 30459219.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    18. Progressive dissociation of cortical and subcortical network development in children with new-onset juvenile myoclonic epilepsy. Epilepsia. 2018 11; 59(11):2086-2095. Garcia-Ramos C, Dabbs K, Lin JJ, Jones JE, Stafstrom CE, Hsu DA, Meyerand ME, Prabhakaran V, Hermann BP. PMID: 30281148.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Hippocampal CA1 gamma power predicts the precision of spatial memory judgments. Proc Natl Acad Sci U S A. 2018 10 02; 115(40):10148-10153. Stevenson RF, Zheng J, Mnatsakanyan L, Vadera S, Knight RT, Lin JJ, Yassa MA. PMID: 30224452.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    20. Neural Mechanisms of Sustained Attention Are Rhythmic. Neuron. 2018 08 22; 99(4):854-865.e5. Helfrich RF, Fiebelkorn IC, Szczepanski SM, Lin JJ, Parvizi J, Knight RT, Kastner S. PMID: 30138591.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    21. Integrated analysis of anatomical and electrophysiological human intracranial data. Nat Protoc. 2018 07; 13(7):1699-1723. Stolk A, Griffin S, van der Meij R, Dewar C, Saez I, Lin JJ, Piantoni G, Schoffelen JM, Knight RT, Oostenveld R. PMID: 29988107.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    22. Using electrocorticogram baseline seizure frequency to assess the efficacy of responsive neurostimulation. Epilepsy Behav. 2018 08; 85:7-9. Young MG, Vadera S, Lin JJ, Mnatsakanyan L. PMID: 29890343.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Dynamic frontotemporal systems process space and time in working memory. PLoS Biol. 2018 03; 16(3):e2004274. Johnson EL, Adams JN, Solbakk AK, Endestad T, Larsson PG, Ivanovic J, Meling TR, Lin JJ, Knight RT. PMID: 29601574.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    24. Mirroring in the Human Brain: Deciphering the Spatial-Temporal Patterns of the Human Mirror Neuron System. Cereb Cortex. 2018 03 01; 28(3):1039-1048. Perry A, Stiso J, Chang EF, Lin JJ, Parvizi J, Knight RT. PMID: 28137724.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    25. Accuracy and Efficacy for Robotic Assistance in Implanting Responsive Neurostimulation Device Electrodes in Bilateral Mesial Temporal Lobe Epilepsy. Oper Neurosurg (Hagerstown). 2018 03 01; 14(3):267-272. Chan AY, Mnatsakanyan L, Sazgar M, Sen-Gupta I, Lin JJ, Hsu FPK, Vadera S. PMID: 29462446.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Modulating Amygdala-Hippocampal Network Communication: A Potential Therapy for Neuropsychiatric Disorders. Neuropsychopharmacology. 2018 01; 43(1):218-219. Zheng J, Lin JJ. PMID: 29192669.
      View in: PubMed   Mentions: 1     Fields:    
    27. Human hippocampal pre-activation predicts behavior. Sci Rep. 2017 07 20; 7(1):5959. Jafarpour A, Piai V, Lin JJ, Knight RT. PMID: 28729738.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Language recovery after epilepsy surgery of the Broca's area. Epilepsy Behav Case Rep. 2018; 9:42-45. Mnatsakanyan L, Vadera S, Ingalls CW, Zheng J, Sazgar M, Hsu FP, Lin JJ. PMID: 29692970.
      View in: PubMed   Mentions:
    29. Spatiotemporal dynamics of word retrieval in speech production revealed by cortical high-frequency band activity. Proc Natl Acad Sci U S A. 2017 06 06; 114(23):E4530-E4538. Riès SK, Dhillon RK, Clarke A, King-Stephens D, Laxer KD, Weber PB, Kuperman RA, Auguste KI, Brunner P, Schalk G, Lin JJ, Parvizi J, Crone NE, Dronkers NF, Knight RT. PMID: 28533406.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    30. Length of stay for patients undergoing invasive electrode monitoring with stereoelectroencephalography and subdural grids correlates positively with increased institutional profitability. Epilepsia. 2017 06; 58(6):1023-1026. Chan AY, Kharrat S, Lundeen K, Mnatsakanyan L, Sazgar M, Sen-Gupta I, Lin JJ, Hsu FPK, Vadera S. PMID: 28426130.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Amygdala-hippocampal dynamics during salient information processing. Nat Commun. 2017 02 08; 8:14413. Zheng J, Anderson KL, Leal SL, Shestyuk A, Gulsen G, Mnatsakanyan L, Vadera S, Hsu FP, Yassa MA, Knight RT, Lin JJ. PMID: 28176756.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    32. Rapid tuning shifts in human auditory cortex enhance speech intelligibility. Nat Commun. 2016 12 20; 7:13654. Holdgraf CR, de Heer W, Pasley B, Rieger J, Crone N, Lin JJ, Knight RT, Theunissen FE. PMID: 27996965.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    33. Disruptions in cortico-subcortical covariance networks associated with anxiety in new-onset childhood epilepsy. Neuroimage Clin. 2016; 12:815-824. Garcia-Ramos C, Lin JJ, Bonilha L, Jones JE, Jackson DC, Prabhakaran V, Hermann BP. PMID: 27830114.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Direct brain recordings reveal hippocampal rhythm underpinnings of language processing. Proc Natl Acad Sci U S A. 2016 10 04; 113(40):11366-11371. Piai V, Anderson KL, Lin JJ, Dewar C, Parvizi J, Dronkers NF, Knight RT. PMID: 27647880.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    35. Mapping the neuropsychological profile of temporal lobe epilepsy using cognitive network topology and graph theory. Epilepsy Behav. 2016 10; 63:9-16. Kellermann TS, Bonilha L, Eskandari R, Garcia-Ramos C, Lin JJ, Hermann BP. PMID: 27532489.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Graph theory and cognition: A complementary avenue for examining neuropsychological status in epilepsy. Epilepsy Behav. 2016 11; 64(Pt B):329-335. Garcia-Ramos C, Lin JJ, Kellermann TS, Bonilha L, Prabhakaran V, Hermann BP. PMID: 27017326.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    37. Comparison of decoding resolution of standard and high-density electrocorticogram electrodes. J Neural Eng. 2016 Apr; 13(2):026016. Wang PT, King CE, McCrimmon CM, Lin JJ, Sazgar M, Hsu FP, Shaw SJ, Millet DE, Chui LA, Liu CY, Do AH, Nenadic Z. PMID: 26859341.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    38. The impact of bilingualism on working memory in pediatric epilepsy. Epilepsy Behav. 2016 Feb; 55:6-10. Veenstra AL, Riley JD, Barrett LE, Muhonen MG, Zupanc M, Romain JE, Lin JJ, Mucci G. PMID: 26720703.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. Developmental Reorganization of the Cognitive Network in Pediatric Epilepsy. PLoS One. 2015; 10(10):e0141186. Garcia-Ramos C, Lin JJ, Prabhakaran V, Hermann BP. PMID: 26505900.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    40. Cognition and brain development in children with benign epilepsy with centrotemporal spikes. Epilepsia. 2015 Oct; 56(10):1615-22. Garcia-Ramos C, Jackson DC, Lin JJ, Dabbs K, Jones JE, Hsu DA, Stafstrom CE, Zawadzki L, Seidenberg M, Prabhakaran V, Hermann BP. PMID: 26337046.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    41. The brain connectome as a personalized biomarker of seizure outcomes after temporal lobectomy. Neurology. 2015 May 05; 84(18):1846-53. Bonilha L, Jensen JH, Baker N, Breedlove J, Nesland T, Lin JJ, Drane DL, Saindane AM, Binder JR, Kuzniecky RI. PMID: 25854868.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    42. Altered organization of face-processing networks in temporal lobe epilepsy. Epilepsia. 2015 May; 56(5):762-71. Riley JD, Fling BW, Cramer SC, Lin JJ. PMID: 25823855.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    43. Mapping the landscape of cognitive development in children with epilepsy. Cortex. 2015 May; 66:1-8. Kellermann TS, Bonilha L, Lin JJ, Hermann BP. PMID: 25776901.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    44. Neurodevelopment in new-onset juvenile myoclonic epilepsy over the first 2 years. Ann Neurol. 2014 Nov; 76(5):660-8. Lin JJ, Dabbs K, Riley JD, Jones JE, Jackson DC, Hsu DA, Stafstrom CE, Seidenberg M, Hermann BP. PMID: 25087843.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    45. Extracting kinetic information from human motor cortical signals. Neuroimage. 2014 Nov 01; 101:695-703. Flint RD, Wang PT, Wright ZA, King CE, Krucoff MO, Schuele SU, Rosenow JM, Hsu FP, Liu CY, Lin JJ, Sazgar M, Millett DE, Shaw SJ, Nenadic Z, Do AH, Slutzky MW. PMID: 25094020.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    46. Birth weight and cognition in children with epilepsy. Epilepsia. 2014 Jun; 55(6):901-8. Jackson DC, Lin JJ, Chambers KL, Kessler-Jones A, Jones JE, Hsu DA, Stafstrom CE, Seidenberg M, Hermann BP. PMID: 24735169.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    47. Neurodevelopmental alterations of large-scale structural networks in children with new-onset epilepsy. Hum Brain Mapp. 2014 Aug; 35(8):3661-72. Bonilha L, Tabesh A, Dabbs K, Hsu DA, Stafstrom CE, Hermann BP, Lin JJ. PMID: 24453089.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    48. Neurobehavioral comorbidities of pediatric epilepsies are linked to thalamic structural abnormalities. Epilepsia. 2013 Dec; 54(12):2116-24. Lin JJ, Siddarth P, Riley JD, Gurbani SG, Ly R, Yee VW, Levitt JG, Toga AW, Caplan R. PMID: 24304435.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    49. Sensitivity and specificity of upper extremity movements decoded from electrocorticogram. Annu Int Conf IEEE Eng Med Biol Soc. 2013; 2013:5618-21. Do AH, Wang PT, King CE, Schombs A, Lin JJ, Sazgar M, Hsu FP, Shaw SJ, Millett DE, Liu CY, Szymanska AA, Chui LA, Nenadic Z. PMID: 24111011.
      View in: PubMed   Mentions:
    50. Imaging and genetics of language and cognition in pediatric epilepsy. Epilepsy Behav. 2013 Mar; 26(3):303-12. Addis L, Lin JJ, Pal DK, Hermann B, Caplan R. PMID: 23116771.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    51. Uncovering the neurobehavioural comorbidities of epilepsy over the lifespan. Lancet. 2012 Sep 29; 380(9848):1180-92. Lin JJ, Mula M, Hermann BP. PMID: 23021287.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    52. Striatal hypertrophy and its cognitive effects in new-onset benign epilepsy with centrotemporal spikes. Epilepsia. 2012 Apr; 53(4):677-85. Lin JJ, Riley JD, Hsu DA, Stafstrom CE, Dabbs K, Becker T, Seidenberg M, Hermann BP. PMID: 22360313.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    53. Ventricular enlargement in new-onset pediatric epilepsies. Epilepsia. 2011 Dec; 52(12):2225-32. Jackson DC, Irwin W, Dabbs K, Lin JJ, Jones JE, Hsu DA, Stafstrom CE, Seidenberg M, Hermann BP. PMID: 22091816.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    54. MRI analysis in temporal lobe epilepsy: cortical thinning and white matter disruptions are related to side of seizure onset. Epilepsia. 2011 Dec; 52(12):2257-66. Kemmotsu N, Girard HM, Bernhardt BC, Bonilha L, Lin JJ, Tecoma ES, Iragui VJ, Hagler DJ, Halgren E, McDonald CR. PMID: 21972957.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    55. Caudate atrophy and impaired frontostriatal connections are linked to executive dysfunction in temporal lobe epilepsy. Epilepsy Behav. 2011 May; 21(1):80-7. Riley JD, Moore S, Cramer SC, Lin JJ. PMID: 21507730.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    56. The neurobiology of cognitive disorders in temporal lobe epilepsy. Nat Rev Neurol. 2011 Mar; 7(3):154-64. Bell B, Lin JJ, Seidenberg M, Hermann B. PMID: 21304484.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    57. Altered white matter integrity in temporal lobe epilepsy: association with cognitive and clinical profiles. Epilepsia. 2010 Apr; 51(4):536-45. Riley JD, Franklin DL, Choi V, Kim RC, Binder DK, Cramer SC, Lin JJ. PMID: 20132296.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    58. Three-dimensional surface maps link local atrophy and fast ripples in human epileptic hippocampus. Ann Neurol. 2009 Dec; 66(6):783-91. Ogren JA, Wilson CL, Bragin A, Lin JJ, Salamon N, Dutton RA, Luders E, Fields TA, Fried I, Toga AW, Thompson PM, Engel J, Staba RJ. PMID: 20035513.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    59. The emerging architecture of neuropsychological impairment in epilepsy. Neurol Clin. 2009 Nov; 27(4):881-907. Hermann BP, Lin JJ, Jones JE, Seidenberg M. PMID: 19853214.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    60. Three-dimensional hippocampal atrophy maps distinguish two common temporal lobe seizure-onset patterns. Epilepsia. 2009 Jun; 50(6):1361-70. Ogren JA, Bragin A, Wilson CL, Hoftman GD, Lin JJ, Dutton RA, Fields TA, Toga AW, Thompson PM, Engel J, Staba RJ. PMID: 19054395.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    61. Vulnerability of the frontal-temporal connections in temporal lobe epilepsy. Epilepsy Res. 2008 Dec; 82(2-3):162-70. Lin JJ, Riley JD, Juranek J, Cramer SC. PMID: 18829258.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    62. Reduced neocortical thickness and complexity mapped in mesial temporal lobe epilepsy with hippocampal sclerosis. Cereb Cortex. 2007 Sep; 17(9):2007-18. Lin JJ, Salamon N, Lee AD, Dutton RA, Geaga JA, Hayashi KM, Luders E, Toga AW, Engel J, Thompson PM. PMID: 17088374.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    63. Three-dimensional preoperative maps of hippocampal atrophy predict surgical outcomes in temporal lobe epilepsy. Neurology. 2005 Oct 11; 65(7):1094-7. Lin JJ, Salamon N, Dutton RA, Lee AD, Geaga JA, Hayashi KM, Toga AW, Engel J, Thompson PM. PMID: 16217065.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
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