Irmina Gradus-Pizlo

Title(s)Health Sciences Professor, Medicine
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
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    1. Virtual reality cognitive intervention for heart failure: CORE study protocol. Alzheimers Dement (N Y). 2022; 8(1):e12230. Jung M, Apostolova LG, Moser DK, Gradus-Pizlo I, Gao S, Rogers JL, Pressler SJ. PMID: 35317082; PMCID: PMC8923344.
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    2. Biventricular thrombi in new-onset cardiomyopathy without an underlying hypercoagulable state: an unusual presentation. Eur Heart J Case Rep. 2022 Jan; 6(1):ytac024. Sinfield S, Harirforoosh S, Wang S, Gradus-Pizlo I. PMID: 35098019; PMCID: PMC8794019.
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    3. 911 Calls for Emergency Medical Services in Heart Failure: A Descriptive Qualitative Study. J Cardiovasc Nurs. 2021 Dec 21. Jung M, Hays LM, Pang PS, Newhouse RP, Arkins TP, O'Donnell D, Cook R, Gradus-Pizlo I, McAdams E, Pressler SJ. PMID: 34935743.
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    4. Randomized Controlled Trial of a Cognitive Intervention to Improve Memory in Heart Failure. J Card Fail. 2022 Apr; 28(4):519-530. Pressler SJ, Jung M, Gradus-Pizlo I, Titler M, Smith D, Gao S, Lake KR, Burney H, Clark D, Wierenga K, Dorsey SG, Giordani B, Pressler SJ, Jung M, Gradus-Pizlo I, Titler MG, Smith DG, Gao S, Lake KR, Burney H, Clark DG, Wierenga KL, Dorsey SG, Giordani B. PMID: 34763080; PMCID: PMC9018491.
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    5. Predictors of emergency medical services use by adults with heart failure; 2009-2017. Heart Lung. 2020 Sep - Oct; 49(5):475-480. Pressler SJ, Jung M, Lee CS, Arkins TP, O'Donnell D, Cook R, Bakoyannis G, Newhouse R, Gradus-Pizlo I, Pang PS. PMID: 32248958.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Design and Rationale of the Cognitive Intervention to Improve Memory in Heart Failure Patients Study. J Cardiovasc Nurs. 2018 Jul/Aug; 33(4):344-355. Pressler SJ, Giordani B, Titler M, Gradus-Pizlo I, Smith D, Dorsey SG, Gao S, Jung M. PMID: 29601367; PMCID: PMC5995611.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    7. Development of a Protocol for Successful Palliative Care Consultation in Population of Patients Receiving Mechanical Circulatory Support. J Pain Symptom Manage. 2017 10; 54(4):583-588. Sinha S, Belcher C, Torke A, Howard J, Caccamo M, Slaven JE, Gradus-Pizlo I. PMID: 28716615.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Genome-Wide Association Study for Anthracycline-Induced Congestive Heart Failure. Clin Cancer Res. 2017 Jan 01; 23(1):43-51. Schneider BP, Shen F, Gardner L, Radovich M, Li L, Miller KD, Jiang G, Lai D, O'Neill A, Sparano JA, Davidson NE, Cameron D, Gradus-Pizlo I, Mastouri RA, Suter TM, Foroud T, Sledge GW. PMID: 27993963; PMCID: PMC5215621.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    9. Pulse Oximeter Derived Blood Pressure Measurement in Patients With a Continuous Flow Left Ventricular Assist Device. Artif Organs. 2017 May; 41(5):424-430. Hellman Y, Malik AS, Lane KA, Shen C, Wang IW, Wozniak TC, Hashmi ZA, Munson SD, Pickrell J, Caccamo MA, Gradus-Pizlo I, Hadi A. PMID: 27782305.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    10. Competence, Compassion, and Care of the Self: Family Caregiving Needs and Concerns in Heart Failure. J Cardiovasc Nurs. 2016 May-Jun; 31(3):209-14. Sullivan BJ, Marcuccilli L, Sloan R, Gradus-Pizlo I, Bakas T, Jung M, Pressler SJ. PMID: 25658185; PMCID: PMC4526444.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. B-Type Natriuretic Peptide Levels Predict Ventricular Arrhythmia Post Left Ventricular Assist Device Implantation. Artif Organs. 2015 Dec; 39(12):1051-5. Hellman Y, Malik AS, Lin H, Shen C, Wang IW, Wozniak TC, Hashmi ZA, Pickrell J, Jani M, Caccamo MA, Gradus-Pizlo I, Hadi A. PMID: 25864448.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. B-type natriuretic peptide-guided therapy and length of hospital stay post left ventricular assist device implantation. ASAIO J. 2015 Mar-Apr; 61(2):156-60. Hellman Y, Malik AS, Lin H, Shen C, Wang IW, Wozniak TC, Hashmi ZA, Shaukat A, Pickrell J, Caccamo MA, Gradus-Pizlo I, Hadi A. PMID: 25485560.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Reducing heart failure readmission rates with an emergency department early readmission alert. Am J Med. 2014 Nov; 127(11):1060-1062. Hadi A, Hellman Y, Malik AS, Caccamo M, Gradus-Pizlo I, Kingery J. PMID: 25107384.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Database queries for hospitalizations for acute congestive heart failure: flexible methods and validation based on set theory. J Am Med Inform Assoc. 2014 Mar-Apr; 21(2):345-52. Rosenman M, He J, Martin J, Nutakki K, Eckert G, Lane K, Gradus-Pizlo I, Hui SL. PMID: 24113802; PMCID: PMC3932461.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    15. Family caregivers of patients with heart failure: a longitudinal study. J Cardiovasc Nurs. 2013 Sep-Oct; 28(5):417-28. Pressler SJ, Gradus-Pizlo I, Chubinski SD, Smith G, Wheeler S, Sloan R, Jung M. PMID: 22760173.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    16. Ventricular arrhythmias in patients with implanted ventricular assist devices: a contemporary review. Europace. 2013 Jan; 15(1):11-7. Shirazi JT, Lopshire JC, Gradus-Pizlo I, Hadi MA, Wozniak TC, Malik AS. PMID: 23233490.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. Frequency, time course, and possible causes of right ventricular systolic dysfunction after cardiac transplantation: a single center experience. Echocardiography. 2013 Jan; 30(1):9-16. Mastouri R, Batres Y, Lenet A, Gradus-Pizlo I, O'Donnell J, Feigenbaum H, Sawada SG. PMID: 22957694.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Patient's age as a factor in the use of diagnostic tools and evidence based therapies in patients with heart failure. Cardiol J. 2012; 19(2):113. Gradus-Pizlo I. PMID: 22461042.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Incremental prognostic value of echocardiography in patients with prior mitral valve surgery. J Heart Valve Dis. 2011 Sep; 20(5):557-64. Jani M, Alhaddad M, Kamalesh M, Gradus-Pizlo I, Mahenthiran J, Feigenbaum H, Sawada S. PMID: 22066361.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Effect of improvement in left ventricular ejection fraction on long-term survival in revascularized patients with ischaemic left ventricular systolic dysfunction. Eur J Echocardiogr. 2011 Jun; 12(6):454-60. Joshi K, Alam I, Ruden E, Gradus-Pizlo I, Mahenthiran J, Kamalesh M, Feigenbaum H, Sawada S. PMID: 21551152.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Feasibility of using real time "Live 3D" echocardiography to visualize the stenotic aortic valve. Echocardiography. 2010 Sep; 27(8):1011-20. Suradi H, Byers S, Green-Hess D, Gradus-Pizlo I, Sawada S, Feigenbaum H. PMID: 20849488.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Effect of revascularization on long-term survival in patients with ischemic left ventricular dysfunction and a wide range of viability. Am J Cardiol. 2010 Jul 15; 106(2):187-92. Sawada SG, Dasgupta S, Nguyen J, Lane KA, Gradus-Pizlo I, Mahenthiran J, Feigenbaum H. PMID: 20599001.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    23. Memory dysfunction, psychomotor slowing, and decreased executive function predict mortality in patients with heart failure and low ejection fraction. J Card Fail. 2010 Sep; 16(9):750-60. Pressler SJ, Kim J, Riley P, Ronis DL, Gradus-Pizlo I. PMID: 20797599; PMCID: PMC2929394.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    24. Cognitive deficits and health-related quality of life in chronic heart failure. J Cardiovasc Nurs. 2010 May-Jun; 25(3):189-98. Pressler SJ, Subramanian U, Kareken D, Perkins SM, Gradus-Pizlo I, Sauvé MJ, Ding Y, Kim J, Sloan R, Jaynes H, Shaw RM. PMID: 20357665; PMCID: PMC2922930.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    25. Measuring depressive symptoms in heart failure: validity and reliability of the patient health questionnaire-8. Am J Crit Care. 2011 Mar; 20(2):146-52. Pressler SJ, Subramanian U, Perkins SM, Gradus-Pizlo I, Kareken D, Kim J, Ding Y, Sauvé MJ, Sloan R. PMID: 20378777.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    26. Cognitive deficits in chronic heart failure. Nurs Res. 2010 Mar-Apr; 59(2):127-39. Pressler SJ, Subramanian U, Kareken D, Perkins SM, Gradus-Pizlo I, Sauvé MJ, Ding Y, Kim J, Sloan R, Jaynes H, Shaw RM. PMID: 20216015; PMCID: PMC2922920.
      View in: PubMed   Mentions: 104     Fields:    Translation:Humans
    27. Diastolic dysfunction: search for therapeutic interventions. Cardiol J. 2010; 17(2):115-6. Gradus-Pizlo I. PMID: 20544608.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Amiodarone hepatotoxicity in the context of the metabolic syndrome and right-sided heart failure. J Gastrointestin Liver Dis. 2009 Dec; 18(4):419-23. Mattar W, Juliar B, Gradus-Pizlo I, Kwo PY. PMID: 20076813.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    29. Wall motion abnormalities with low-dose dobutamine predict a high risk of cardiac death in medically treated patients with ischemic cardiomyopathy. Clin Cardiol. 2009 Jul; 32(7):403-9. Maskoun W, Mustafa N, Mahenthiran J, Gradus-Pizlo I, Kamalesh M, Feigenbaum H, Sawada SG. PMID: 19609896; PMCID: PMC6652903.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Clinical assessment and rest and stress echocardiography for prediction of long-term prognosis in African Americans with known or suspected coronary artery disease. Echocardiography. 2009 May; 26(5):558-66. Sawada SG, Sayyed S, Raiesdana A, Gradus-Pizlo I, Mahenthiran J, Feigenbaum H. PMID: 19452609.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Family caregiver outcomes in heart failure. Am J Crit Care. 2009 Mar; 18(2):149-59. Pressler SJ, Gradus-Pizlo I, Chubinski SD, Smith G, Wheeler S, Wu J, Sloan R. PMID: 19255105; PMCID: PMC2651565.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    32. Evaluation of the anti-ischemic effects of D-ribose during dobutamine stress echocardiography: a pilot study. Cardiovasc Ultrasound. 2009 Feb 07; 7:5. Sawada SG, Lewis S, Kovacs R, Khouri S, Gradus-Pizlo I, St Cyr JA, Feigenbaum H. PMID: 19200398; PMCID: PMC2644671.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    33. Research in patients with heart failure: challenges in recruitment. Am J Crit Care. 2008 May; 17(3):198-203. Pressler SJ, Subramanian U, Shaw RM, Meyer LE, Stoudemire K, Gradus-Pizlo I. PMID: 18450677.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    34. Prediction of ischemic events by anatomic M-mode strain rate stress echocardiography. J Am Soc Echocardiogr. 2008 Apr; 21(4):299-306. Mastouri R, Mahenthiran J, Kamalesh M, Gradus-Pizlo I, Feigenbaum H, Sawada SG. PMID: 18187305.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. Stress-induced wall motion abnormalities with low-dose dobutamine infusion indicate the presence of severe disease and vulnerable myocardium. Echocardiography. 2007 Aug; 24(7):739-44. Sawada SG, Safadi A, Gaitonde RS, Tung N, Mahenthiran J, Gill W, Ghumman W, Gradus-Pizlo I, Kamalesh M, Fineberg N, Feigenbaum H. PMID: 17651103.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    36. Pharmacist intervention to improve medication adherence in heart failure: a randomized trial. Ann Intern Med. 2007 May 15; 146(10):714-25. Murray MD, Young J, Hoke S, Tu W, Weiner M, Morrow D, Stroupe KT, Wu J, Clark D, Smith F, Gradus-Pizlo I, Weinberger M, Brater DC. PMID: 17502632.
      View in: PubMed   Mentions: 143     Fields:    Translation:Humans
    37. Multiple alcohol septal ablations in a young patient with hypertrophic cardiomyopathy. Cardiol J. 2007; 14(3):301-4. Rampurwala AY, Gradus-Pizlo I. PMID: 18651475.
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    38. How to improve delivery of care in patients with heart failure. Cardiol J. 2007; 14(6):521-2. Gradus-Pizlo I. PMID: 18651516.
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    39. Comparison of tissue Doppler dynamics to Doppler flow in evaluating left atrial appendage function by transesophageal echocardiography. Am J Cardiol. 2005 Apr 15; 95(8):1011-4. Parvathaneni L, Mahenthiran J, Jacob S, Foltz J, Gill WJ, Ghumman W, Gradus-Pizlo I, Feigenbaum H, Sawada SG. PMID: 15820180.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    40. Patient perception and provider assessment of severity of heart failure as predictors of hospitalization. Heart Lung. 2005 Mar-Apr; 34(2):89-98. Subramanian U, Weiner M, Gradus-Pizlo I, Wu J, Tu W, Murray MD. PMID: 15761453.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    41. Health care and medication costs and use among older adults with heart failure. Am J Med. 2004 Apr 01; 116(7):443-50. Stroupe KT, Teal EY, Weiner M, Gradus-Pizlo I, Brater DC, Murray MD. PMID: 15047033.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    42. Methodology of an ongoing, randomized, controlled trial to improve drug use for elderly patients with chronic heart failure. Am J Geriatr Pharmacother. 2004 Mar; 2(1):53-65. Murray MD, Young JM, Morrow DG, Weiner M, Tu W, Hoke SC, Clark DO, Stroupe KT, Wu J, Deer MM, Bruner-England TE, Sowinski KM, Smith FE, Oldridge NB, Gradus-Pizlo I, Murray LL, Brater DC, Weinberger M. PMID: 15555479.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    43. Incremental value of myocardial viability for prediction of long-term prognosis in surgically revascularized patients with left ventricular dysfunction. J Am Coll Cardiol. 2003 Dec 17; 42(12):2099-105. Sawada S, Bapat A, Vaz D, Weksler J, Fineberg N, Greene A, Gradus-Pizlo I, Feigenbaum H. PMID: 14680734.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    44. Left anterior descending coronary artery wall thickness measured by high-frequency transthoracic and epicardial echocardiography includes adventitia. Am J Cardiol. 2003 Jan 01; 91(1):27-32. Gradus-Pizlo I, Bigelow B, Mahomed Y, Sawada SG, Rieger K, Feigenbaum H. PMID: 12505567.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    45. Potential use of high-resolution two-dimensional transthoracic echocardiography for visualization of the left anterior descending coronary artery. Am Heart Hosp J. 2003; 1(1):77-82. Gradus-Pizlo I, Feigenbaum H. PMID: 15785180.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. Imaging of the left anterior descending coronary artery by high-frequency transthoracic and epicardial echocardiography. Am J Cardiol. 2002 Nov 21; 90(10C):28L-31L. Gradus-Pizlo I, Feigenbaum H. PMID: 12459424.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    47. Usefulness of rest and low-dose dobutamine wall motion scores in predicting survival and benefit from revascularization in patients with ischemic cardiomyopathy. Am J Cardiol. 2002 Apr 01; 89(7):811-6. Sawada SG, Lewis SJ, Foltz J, Ando A, Khouri S, Kaser S, Gradus-Pizlo I, Gill W, Fineberg N, Segar D, Feigenbaum H. PMID: 11909564.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    48. Echocardiographic imaging of technically difficult patients in the intensive care unit: use of optison in combination with fundamental and harmonic imaging. J Am Soc Echocardiogr. 2001 Sep; 14(9):917-20. Daniel GK, Chawla MK, Sawada SG, Gradus-Pizlo I, Feigenbaum H, Segar DS. PMID: 11547278.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    49. Treatment of vascular thrombosis with enoxaparin in orthotopic heart transplant patients during the early postoperative period. J Heart Lung Transplant. 2001 Sep; 20(9):1025-9. Lopshire JC, Darroca AG, Gradus-Pizlo I, O'Donnell JA. PMID: 11557199.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    50. Detection of subclinical coronary atherosclerosis using two-dimensional, high-resolution transthoracic echocardiography. J Am Coll Cardiol. 2001 Apr; 37(5):1422-9. Gradus-Pizlo I, Sawada SG, Wright D, Segar DS, Feigenbaum H. PMID: 11300456.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    51. Vascular repair mechanisms after directional atherectomy or percutaneous transluminal coronary angioplasty in atherosclerotic rabbit iliac arteries. Am Heart J. 1996 Jul; 132(1 Pt 1):13-22. Wilensky RL, Gradus-Pizlo I, Sandusky G, March KL. PMID: 8701854.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    52. Vascular injury, repair, and restenosis after percutaneous transluminal angioplasty in the atherosclerotic rabbit. Circulation. 1995 Nov 15; 92(10):2995-3005. Wilensky RL, March KL, Gradus-Pizlo I, Sandusky G, Fineberg N, Hathaway DR. PMID: 7586270.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    53. Local delivery of biodegradable microparticles containing colchicine or a colchicine analogue: effects on restenosis and implications for catheter-based drug delivery. J Am Coll Cardiol. 1995 Nov 15; 26(6):1549-57. Gradus-Pizlo I, Wilensky RL, March KL, Fineberg N, Michaels M, Sandusky GE, Hathaway DR. PMID: 7594084.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsPHPublic Health
    54. Regional and arterial localization of radioactive microparticles after local delivery by unsupported or supported porous balloon catheters. Am Heart J. 1995 May; 129(5):852-9. Wilensky RL, March KL, Gradus-Pizlo I, Schauwecker D, Michaels MB, Robinson J, Carlson K, Hathaway DR. PMID: 7732972.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    55. Methods and devices for local drug delivery in coronary and peripheral arteries. Trends Cardiovasc Med. 1993 Sep-Oct; 3(5):163-70. Wilensky RL, March KL, Gradus-Pizlo I, Spaedy AJ, Hathaway DR. PMID: 21244928.
      View in: PubMed   Mentions: 1     Fields:    
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