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Moradi, Hamid

TitleAssociate Health Sciences Professor
InstitutionUniversity of California, Irvine
DepartmentMedicine
Address1001 Health Sciences Road
CA 92697-3950
Phone(714) 456-5560, 5142, 6670
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    Collapse Research 
    Collapse Research Activities and Funding
    HDL function and mortality in end stage renal disease
    VA IK2CX001043Jan 1, 2015 - Dec 31, 2019
    Role: Principal Investigator
    Mechanisms involved in uremic toxin mediated down regulation of ApoA-I expression
    NIH/NIDDK F32DK082130Jul 1, 2009 - Jun 30, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chang TI, Streja E, Ko GJ, Naderi N, Rhee CM, Kovesdy CP, Kashyap ML, Vaziri ND, Kalantar-Zadeh K, Moradi H. Inverse Association Between Serum Non-High-Density Lipoprotein Cholesterol Levels and Mortality in Patients Undergoing Incident Hemodialysis. J Am Heart Assoc. 2018 Jun 09; 7(12). PMID: 29886420.
      View in: PubMed
    2. Kleine CE, Soohoo M, Ranasinghe ON, Park C, Marroquin MV, Obi Y, Rhee CM, Moradi H, Kovesdy CP, Kalantar-Zadeh K, Streja E. Association of Pre-End-Stage Renal Disease Hemoglobin with Early Dialysis Outcomes. Am J Nephrol. 2018; 47(5):333-342. PMID: 29779027.
      View in: PubMed
    3. Moradi H, Streja E, Vaziri ND. ESRD-induced dyslipidemia-Should management of lipid disorders differ in dialysis patients? Semin Dial. 2018 Apr 29. PMID: 29707830.
      View in: PubMed
    4. Saran R, Robinson B, Abbott KC, Agodoa LYC, Bhave N, Bragg-Gresham J, Balkrishnan R, Dietrich X, Eckard A, Eggers PW, Gaipov A, Gillen D, Gipson D, Hailpern SM, Hall YN, Han Y, He K, Herman W, Heung M, Hirth RA, Hutton D, Jacobsen SJ, Jin Y, Kalantar-Zadeh K, Kapke A, Kovesdy CP, Lavallee D, Leslie J, McCullough K, Modi Z, Molnar MZ, Montez-Rath M, Moradi H, Morgenstern H, Mukhopadhyay P, Nallamothu B, Nguyen DV, Norris KC, O'Hare AM, Obi Y, Park C, Pearson J, Pisoni R, Potukuchi PK, Rao P, Repeck K, Rhee CM, Schrager J, Schaubel DE, Selewski DT, Shaw SF, Shi JM, Shieu M, Sim JJ, Soohoo M, Steffick D, Streja E, Sumida K, Tamura MK, Tilea A, Tong L, Wang D, Wang M, Woodside KJ, Xin X, Yin M, You AS, Zhou H, Shahinian V. US Renal Data System 2017 Annual Data Report: Epidemiology of Kidney Disease in the United States. Am J Kidney Dis. 2018 Mar; 71(3S1):A7. PMID: 29477157.
      View in: PubMed
    5. Chang TI, Streja E, Soohoo M, Ko GJ, Rhee CM, Kovesdy CP, Kashyap ML, Vaziri ND, Kalantar-Zadeh K, Moradi H. Increments in serum high-density lipoprotein cholesterol over time are not associated with improved outcomes in incident hemodialysis patients. J Clin Lipidol. 2018 Mar - Apr; 12(2):488-497. PMID: 29456130.
      View in: PubMed
    6. Suematsu Y, Jing W, Nunes A, Kashyap ML, Khazaeli M, Vaziri ND, Moradi H. LCZ696 (Sacubitril/Valsartan), an Angiotensin-Receptor Neprilysin Inhibitor, Attenuates Cardiac Hypertrophy, Fibrosis, and Vasculopathy in a Rat Model of Chronic Kidney Disease. J Card Fail. 2018 Apr; 24(4):266-275. PMID: 29325796.
      View in: PubMed
    7. Moradi H, Vaziri ND. Molecular mechanisms of disorders of lipid metabolism in chronic kidney disease. Front Biosci (Landmark Ed). 2018 Jan 01; 23:146-161. PMID: 28930541.
      View in: PubMed
    8. Jing W, Vaziri ND, Nunes A, Suematsu Y, Farzaneh T, Khazaeli M, Moradi H. LCZ696 (Sacubitril/valsartan) ameliorates oxidative stress, inflammation, fibrosis and improves renal function beyond angiotensin receptor blockade in CKD. Am J Transl Res. 2017; 9(12):5473-5484. PMID: 29312499.
      View in: PubMed
    9. Moradi H, Streja E, Kalantar-Zadeh K. Serum high density lipoprotein cholesterol level and risk of death: let's avoid the extremes. J Thorac Dis. 2017 Dec; 9(12):4849-4852. PMID: 29312674.
      View in: PubMed
    10. Subramanian VS, Sabui S, Moradi H, Marchant JS, Said HM. Inhibition of intestinal ascorbic acid uptake by lipopolysaccharide is mediated via transcriptional mechanisms. Biochim Biophys Acta. 2018 02; 1860(2):556-565. PMID: 29030247.
      View in: PubMed
    11. Park F, Potukuchi PK, Moradi H, Kovesdy CP. Cannabinoids and the kidney: effects in health and disease. Am J Physiol Renal Physiol. 2017 Nov 01; 313(5):F1124-F1132. PMID: 28747360.
      View in: PubMed
    12. Soohoo M, Ahmadi SF, Qader H, Streja E, Obi Y, Moradi H, Rhee CM, Kim TH, Kovesdy CP, Kalantar-Zadeh K. Association of serum vitamin B12 and folate with mortality in incident hemodialysis patients. Nephrol Dial Transplant. 2017 Jun 01; 32(6):1024-1032. PMID: 27190367.
      View in: PubMed
    13. Kalantar-Zadeh K, Crowley ST, Beddhu S, Chen JLT, Daugirdas JT, Goldfarb DS, Jin A, Kovesdy CP, Leehey DJ, Moradi H, Navaneethan SD, Norris KC, Obi Y, O'Hare A, Shafi T, Streja E, Unruh ML, Vachharajani TJ, Weisbord S, Rhee CM. Renal Replacement Therapy and Incremental Hemodialysis for Veterans with Advanced Chronic Kidney Disease. Semin Dial. 2017 05; 30(3):251-261. PMID: 28421638.
      View in: PubMed
    14. Chang TI, Streja E, Moradi H. Could high-density lipoprotein cholesterol predict increased cardiovascular risk? Curr Opin Endocrinol Diabetes Obes. 2017 Apr; 24(2):140-147. PMID: 28099207.
      View in: PubMed
    15. Perl J, Dember LM, Bargman JM, Browne T, Charytan DM, Flythe JE, Hickson LJ, Hung AM, Jadoul M, Lee TC, Meyer KB, Moradi H, Shafi T, Teitelbaum I, Wong LP, Chan CT. The Use of a Multidimensional Measure of Dialysis Adequacy-Moving beyond Small Solute Kinetics. Clin J Am Soc Nephrol. 2017 May 08; 12(5):839-847. PMID: 28314806.
      View in: PubMed
    16. Chang TI, Streja E, Soohoo M, Kim TW, Rhee CM, Kovesdy CP, Kashyap ML, Vaziri ND, Kalantar-Zadeh K, Moradi H. Association of Serum Triglyceride to HDL Cholesterol Ratio with All-Cause and Cardiovascular Mortality in Incident Hemodialysis Patients. Clin J Am Soc Nephrol. 2017 Apr 03; 12(4):591-602. PMID: 28193609.
      View in: PubMed
    17. Moradi H, Oveisi F, Khanifar E, Moreno-Sanz G, Vaziri ND, Piomelli D. Increased Renal 2-Arachidonoylglycerol Level Is Associated with Improved Renal Function in a Mouse Model of Acute Kidney Injury. Cannabis Cannabinoid Res. 2016; 1(1):218-228. PMID: 28861493.
      View in: PubMed
    18. Moradi H, Said HM. Functional thiamine deficiency in end-stage renal disease: malnutrition despite ample nutrients. Kidney Int. 2016 08; 90(2):252-254. PMID: 27418090.
      View in: PubMed
    19. Moradi H, Vaziri ND. Effect of resveratrol on progression of polycystic kidney disease: a case of cautious optimism. Nephrol Dial Transplant. 2016 11; 31(11):1755-1758. PMID: 27190353.
      View in: PubMed
    20. Vashistha T, Streja E, Molnar MZ, Rhee CM, Moradi H, Soohoo M, Kovesdy CP, Kalantar-Zadeh K. Red Cell Distribution Width and Mortality in Hemodialysis Patients. Am J Kidney Dis. 2016 Jul; 68(1):110-21. PMID: 26786297; PMCID: PMC4921311 [Available on 07/01/17].
    21. Doshi M, Streja E, Rhee CM, Park J, Ravel VA, Soohoo M, Moradi H, Lau WL, Mehrotra R, Kuttykrishnan S, Kovesdy CP, Kalantar-Zadeh K, Chen JL. Examining the robustness of the obesity paradox in maintenance hemodialysis patients: a marginal structural model analysis. Nephrol Dial Transplant. 2016 08; 31(8):1310-9. PMID: 26590266; PMCID: PMC4967726 [Available on 08/01/17].
    22. Ahmadi SF, Streja E, Zahmatkesh G, Streja D, Kashyap M, Moradi H, Molnar MZ, Reddy U, Amin AN, Kovesdy CP, Kalantar-Zadeh K. Reverse Epidemiology of Traditional Cardiovascular Risk Factors in the Geriatric Population. J Am Med Dir Assoc. 2015 Nov 01; 16(11):933-9. PMID: 26363864.
      View in: PubMed
    23. Ravel V, Streja E, Molnar MZ, Rezakhani S, Soohoo M, Kovesdy CP, Kalantar-Zadeh K, Moradi H. Association of aspartate aminotransferase with mortality in hemodialysis patients. Nephrol Dial Transplant. 2016 05; 31(5):814-22. PMID: 26333544; PMCID: PMC4848754 [Available on 05/01/17].
    24. Moradi H, Abhari P, Streja E, Kashyap ML, Shah G, Gillen D, Pahl MV, Vaziri ND, Kalantar-Zadeh K. Association of serum lipids with outcomes in Hispanic hemodialysis patients of the West versus East Coasts of the United States. Am J Nephrol. 2015; 41(4-5):284-95. PMID: 26044456.
      View in: PubMed
    25. Rhee CM, Nguyen DV, Moradi H, Brunelli SM, Dukkipati R, Jing J, Nakata T, Kovesdy CP, Brent GA, Kalantar-Zadeh K. Association of Adiponectin With Body Composition and Mortality in Hemodialysis Patients. Am J Kidney Dis. 2015 Aug; 66(2):313-21. PMID: 25824125; PMCID: PMC4516594.
    26. Streja E, Kovesdy CP, Streja DA, Moradi H, Kalantar-Zadeh K, Kashyap ML. Niacin and progression of CKD. Am J Kidney Dis. 2015 May; 65(5):785-98. PMID: 25708553.
      View in: PubMed
    27. Kalantar-Zadeh K, Tortorici AR, Chen JL, Kamgar M, Lau WL, Moradi H, Rhee CM, Streja E, Kovesdy CP. Dietary restrictions in dialysis patients: is there anything left to eat? Semin Dial. 2015 Mar-Apr; 28(2):159-68. PMID: 25649719; PMCID: PMC4385746.
    28. Li L, Fisher M, Lau WL, Moradi H, Cheung A, Thai G, Handwerker J, Kalantar-Zadeh K. Cerebral microbleeds and cognitive decline in a hemodialysis patient: Case report and review of literature. Hemodial Int. 2015 Jul; 19(3):E1-7. PMID: 25175449; PMCID: PMC4345139.
    29. Vaziri ND, Moradi H. Dual role of circulating angiopoietin-like 4 (ANGPTL4) in promoting hypertriglyceridemia and lowering proteinuria in nephrotic syndrome. Am J Kidney Dis. 2014 Oct; 64(4):495-8. PMID: 24838183.
      View in: PubMed
    30. Moradi H, Streja E, Kashyap ML, Vaziri ND, Fonarow GC, Kalantar-Zadeh K. Elevated high-density lipoprotein cholesterol and cardiovascular mortality in maintenance hemodialysis patients. Nephrol Dial Transplant. 2014 Aug; 29(8):1554-62. PMID: 24574544; PMCID: PMC4106641.
    31. Rhee CM, Lertdumrongluk P, Streja E, Park J, Moradi H, Lau WL, Norris KC, Nissenson AR, Amin AN, Kovesdy CP, Kalantar-Zadeh K. Impact of age, race and ethnicity on dialysis patient survival and kidney transplantation disparities. Am J Nephrol. 2014; 39(3):183-94. PMID: 24556752; PMCID: PMC4024458.
    32. Hatamizadeh P, Ravel V, Lukowsky LR, Molnar MZ, Moradi H, Harley K, Pahl M, Kovesdy CP, Kalantar-Zadeh K. Iron indices and survival in maintenance hemodialysis patients with and without polycystic kidney disease. Nephrol Dial Transplant. 2013 Nov; 28(11):2889-98. PMID: 24169614; PMCID: PMC3811063.
    33. Moradi H, Wang PH. Renoprotective mechanisms of ischemic postconditioning in ischemia-reperfusion injury: improved mitochondrial function and integrity. Nephrol Dial Transplant. 2013 Nov; 28(11):2667-9. PMID: 24169608; PMCID: PMC3811058.
    34. Moradi H, Sica DA, Kalantar-Zadeh K. Cardiovascular burden associated with uremic toxins in patients with chronic kidney disease. Am J Nephrol. 2013; 38(2):136-48. PMID: 23941724.
      View in: PubMed
    35. Yazdi PG, Moradi H, Yang JY, Wang PH, Vaziri ND. Skeletal muscle mitochondrial depletion and dysfunction in chronic kidney disease. Int J Clin Exp Med. 2013; 6(7):532-9. PMID: 23936591; PMCID: PMC3731184.
    36. Moradi H, Vaziri ND, Kashyap ML, Said HM, Kalantar-Zadeh K. Role of HDL dysfunction in end-stage renal disease: a double-edged sword. J Ren Nutr. 2013 May; 23(3):203-6. PMID: 23611547.
      View in: PubMed
    37. Lertdumrongluk P, Rhee CM, Park J, Lau WL, Moradi H, Jing J, Molnar MZ, Brunelli SM, Nissenson AR, Kovesdy CP, Kalantar-Zadeh K. Association of serum phosphorus concentration with mortality in elderly and nonelderly hemodialysis patients. J Ren Nutr. 2013 Nov; 23(6):411-21. PMID: 23631888; PMCID: PMC3735629.
    38. Subramanian VS, Nabokina SM, Patton JR, Marchant JS, Moradi H, Said HM. Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis. Am J Physiol Gastrointest Liver Physiol. 2013 Jun 15; 304(12):G1079-86. PMID: 23599041; PMCID: PMC3680717.
    39. Han S, Vaziri ND, Gollapudi P, Kwok V, Moradi H. Hepatic fatty acid and cholesterol metabolism in nephrotic syndrome. Am J Transl Res. 2013; 5(2):246-53. PMID: 23573368; PMCID: PMC3612519.
    40. Moradi H, Said HM, Vaziri ND. Post-transcriptional nature of uremia-induced downregulation of hepatic apolipoprotein A-I production. Transl Res. 2013 Jun; 161(6):477-85. PMID: 23219399; PMCID: PMC3609941.
    41. Vaziri ND, Goshtasbi N, Yuan J, Jellbauer S, Moradi H, Raffatellu M, Kalantar-Zadeh K. Uremic plasma impairs barrier function and depletes the tight junction protein constituents of intestinal epithelium. Am J Nephrol. 2012; 36(5):438-43. PMID: 23128155; PMCID: PMC3725306.
    42. Vaziri ND, Navab K, Gollapudi P, Moradi H, Pahl MV, Barton CH, Fogelman AM, Navab M. Salutary effects of hemodialysis on low-density lipoprotein proinflammatory and high-density lipoprotein anti-inflammatory properties in patient with end-stage renal disease. J Natl Med Assoc. 2011 Jun; 103(6):524-33. PMID: 21830637; PMCID: PMC3276406.
    43. Vaziri ND, Gollapudi P, Han S, Farahmand G, Yuan J, Rahimi A, Moradi H. Nephrotic syndrome causes upregulation of HDL endocytic receptor and PDZK-1-dependent downregulation of HDL docking receptor. Nephrol Dial Transplant. 2011 Oct; 26(10):3118-23. PMID: 21459782.
      View in: PubMed
    44. Bukhari FJ, Moradi H, Gollapudi P, Ju Kim H, Vaziri ND, Said HM. Effect of chronic kidney disease on the expression of thiamin and folic acid transporters. Nephrol Dial Transplant. 2011 Jul; 26(7):2137-44. PMID: 21149507; PMCID: PMC3164444.
    45. Vaziri ND, Kim HJ, Moradi H, Farmand F, Navab K, Navab M, Hama S, Fogelman AM, Quiroz Y, Rodriguez-Iturbe B. Amelioration of nephropathy with apoA-1 mimetic peptide in apoE-deficient mice. Nephrol Dial Transplant. 2010 Nov; 25(11):3525-34. PMID: 20488818; PMCID: PMC2980997.
    46. Vaziri ND, Moradi H, Pahl MV, Fogelman AM, Navab M. In vitro stimulation of HDL anti-inflammatory activity and inhibition of LDL pro-inflammatory activity in the plasma of patients with end-stage renal disease by an apoA-1 mimetic peptide. Kidney Int. 2009 Aug; 76(4):437-44. PMID: 19471321; PMCID: PMC3280585.
    47. Kim HJ, Moradi H, Yuan J, Norris K, Vaziri ND. Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney. Am J Physiol Renal Physiol. 2009 Jun; 296(6):F1297-306. PMID: 19357177; PMCID: PMC2692452.
    48. Moradi H, Yuan J, Ni Z, Norris K, Vaziri ND. Reverse cholesterol transport pathway in experimental chronic renal failure. Am J Nephrol. 2009; 30(2):147-54. PMID: 19321994; PMCID: PMC2813810.
    49. Pahl MV, Ni Z, Sepassi L, Moradi H, Vaziri ND. Plasma phospholipid transfer protein, cholesteryl ester transfer protein and lecithin:cholesterol acyltransferase in end-stage renal disease (ESRD). Nephrol Dial Transplant. 2009 Aug; 24(8):2541-6. PMID: 19297356; PMCID: PMC2727299.
    50. Moradi H, Pahl MV, Elahimehr R, Vaziri ND. Impaired antioxidant activity of high-density lipoprotein in chronic kidney disease. Transl Res. 2009 Feb; 153(2):77-85. PMID: 19138652.
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    51. Moradi H, Kwok V, Vaziri ND. Effect of chronic renal failure on arginase and argininosuccinate synthetase expression. Am J Nephrol. 2006; 26(3):310-8. PMID: 16809898.
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    52. Vaziri ND, Moradi H. Mechanisms of dyslipidemia of chronic renal failure. Hemodial Int. 2006 Jan; 10(1):1-7. PMID: 16441821.
      View in: PubMed