-
Merging Natural Product Structures with Pharmaceutical Leads: Unnatural Enantiomers of Estranes as Glucocorticoid Receptor Modulators That Suppress TNF-α and IL-6 Release. J Med Chem. 2024 Sep 26; 67(18):16185-16194.
Nicholson JM, Yang D, Koelblen T, Hu EL, Coss CC, Burris TP, Hu X, Micalizio GC. PMID: 39240657; PMCID: PMC11609614.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Function-Oriented Synthesis of Pentacyclic Triterpenoids and Discovery of an ent-Estrane as a Natural Product-Inspired Androgen Receptor Antagonist. Org Lett. 2024 Apr 19; 26(15):3054-3059.
Stempel ZD, Radomska HS, Coss CC, Micalizio GC. PMID: 38557107; PMCID: PMC11590179.
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PubMed Mentions: Fields:
-
From Functional Fatty Acids to Potent and Selective Natural-Product-Inspired Mimetics via Conformational Profiling. ACS Cent Sci. 2024 Feb 28; 10(2):477-486.
Markham LE, Koelblen T, Chobanian HR, Follis AV, Burris TP, Micalizio GC. PMID: 38435518; PMCID: PMC10906247.
View in:
PubMed Mentions:
-
Progress Toward the Asymmetric De Novo Synthesis of Limonoids. Org Lett. 2024 02 09; 26(5):1073-1077.
Fazekas TJ, Micalizio GC. PMID: 38277646.
View in:
PubMed Mentions: Fields:
-
Asymmetric Total Syntheses of Euphol and Tirucallol. Org Lett. 2023 Aug 04; 25(30):5687-5691.
Nicholson JM, Micalizio GC. PMID: 37477981; PMCID: PMC10654682.
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PubMed Mentions: Fields:
-
Progress Toward the Asymmetric de Novo Synthesis of Lanostanes: A Counter Biomimetic Cucurbitane-to-Lanostane Type Transformation. Tetrahedron. 2023 Jul 17; 141.
Bucknam AR, Micalizio GC. PMID: 37637188; PMCID: PMC10455037.
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PubMed Mentions: Fields:
-
Toward the Asymmetric de Novo Synthesis of Lanostanes: Construction of 7,11-Dideoxy-Δ5-lucidadone H. J Org Chem. 2022 11 04; 87(21):14975-14979.
Wai H, Micalizio GC. PMID: 36206482; PMCID: PMC9662812.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Toward the Asymmetric Synthesis of Cardenolides and Related Steroidal Systems: syn-SN2' of Organometallics with C14-C17 Vinylepoxides. Org Lett. 2022 Oct 07; 24(39):7058-7061.
Millham AB, Micalizio GC. PMID: 36154235; PMCID: PMC9637385.
View in:
PubMed Mentions: Fields:
-
Progress toward the De Novo Asymmetric Synthesis of Euphanes. Org Lett. 2022 05 27; 24(20):3686-3690.
Wai H, Koelblen T, Hayes ME, Burris TP, Micalizio GC. PMID: 35584298; PMCID: PMC9419992.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Asymmetric De Novo Synthesis of a Cucurbitane Triterpenoid: Total Synthesis of Octanorcucurbitacin B. J Am Chem Soc. 2022 05 18; 144(19):8493-8497.
Bucknam AR, Micalizio GC. PMID: 35533213; PMCID: PMC9410570.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
-
General Enantioselective and Stereochemically Divergent Four-Stage Approach to Fused Tetracyclic Terpenoid Systems. J Org Chem. 2022 03 04; 87(5):3352-3362.
Nicholson JM, Millham AB, Bucknam AR, Markham LE, Sailors XI, Micalizio GC. PMID: 35175755; PMCID: PMC9438405.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
An Enantiodefined Conformationally Constrained Fatty Acid Mimetic and Potent Inhibitor of ToxT. ACS Med Chem Lett. 2021 Sep 09; 12(9):1493-1497.
Markham LE, Tolbert JD, Kull FJ, Midgett CR, Micalizio GC. PMID: 34531958; PMCID: PMC8436414.
View in:
PubMed Mentions:
5
-
From an ent-Estrane, through a nat-Androstane, to the Total Synthesis of the Marine-Derived Δ8,9-Pregnene (+)-03219A. Org Lett. 2021 03 19; 23(6):2248-2252.
Shalit ZA, Valdes LC, Kim WS, Micalizio GC. PMID: 33635666; PMCID: PMC8420867.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
-
From Metallacycle-Mediated Annulative Cross-Coupling to Steroidal Tetracycles through Intramolecular C9-C10 Bond Formation. Org Lett. 2020 08 21; 22(16):6595-6599.
Millham AB, Bhatt CP, Micalizio GC. PMID: 32806140; PMCID: PMC7518127.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
-
Synthesis of Anhydroryanodol. J Am Chem Soc. 2020 07 29; 142(30):12937-12941.
Du K, Kier MJ, Stempel ZD, Jeso V, Rheingold AL, Micalizio GC. PMID: 32609506; PMCID: PMC7477650.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Studies Targeting Ryanodol Result in an Annulation Reaction for the Synthesis of a Variety of Fused Carbocycles. Org Lett. 2019 08 02; 21(15):6126-6129.
Karmakar R, Rheingold AL, Micalizio GC. PMID: 31298546; PMCID: PMC6677624.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ. Nat Commun. 2019 06 04; 10(1):2448.
Kim WS, Shalit ZA, Nguyen SM, Schoepke E, Eastman A, Burris TP, Gaur AB, Micalizio GC. PMID: 31164645; PMCID: PMC6547701.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Synthesis of C14-Desmethylene Corialactone D and Discovery of Inhibitors of Nerve Growth Factor Mediated Neurite Outgrowth. Org Lett. 2019 05 03; 21(9):3193-3197.
Leon RM, Ravi D, An JS, Del Genio CL, Rheingold AL, Gaur AB, Micalizio GC. PMID: 30995050; PMCID: PMC8420866.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
A Complementary Process to Pauson-Khand-Type Annulation Reactions for the Construction of Fully Substituted Cyclopentenones. Org Lett. 2019 01 18; 21(2):567-570.
Millham AB, Kier MJ, Leon RM, Karmakar R, Stempel ZD, Micalizio GC. PMID: 30614709; PMCID: PMC6465167.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Toward the Total Synthesis of Ryanodol via Oxidative Alkyne-1,3-Diketone Annulation: Construction of a Ryanoid Tetracycle. Org Lett. 2018 10 19; 20(20):6457-6461.
Du K, Kier MJ, Rheingold AL, Micalizio GC. PMID: 30264570; PMCID: PMC6199674.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
-
Synthesis and Discovery of Estra-1,3,5(10),6,8-pentaene-2,16α-diol. Org Lett. 2018 10 05; 20(19):6220-6224.
Wai H, Du K, Anesini J, Kim WS, Eastman A, Micalizio GC. PMID: 30221523; PMCID: PMC6415968.
View in:
PubMed Mentions:
4 Fields:
-
A Highly Chemo-, Regio-, and Stereoselective Metallacycle-Mediated Annulation Between a Conjugated Enyne and an Ene-Diyne. ARKIVOC. 2018; 2018(4):132-138.
Shalit ZA, Micalizio GC. PMID: 31742254; PMCID: PMC6860972.
View in:
PubMed Mentions:
-
Synthetic nat- or ent-steroids in as few as five chemical steps from epichlorohydrin. Nat Chem. 2018 01; 10(1):70-77.
Kim WS, Du K, Eastman A, Hughes RP, Micalizio GC. PMID: 29256503; PMCID: PMC5821131.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Function-Oriented Studies Targeting Pectenotoxin 2: Synthesis of the GH-Ring System and a Structurally Simplified Macrolactone. Org Lett. 2017 10 06; 19(19):5154-5157.
O'Rourke NF, A M, Higgs HN, Eastman A, Micalizio GC. PMID: 28901150; PMCID: PMC5633828.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
-
Synthesis of Highly Oxygenated Carbocycles by Stereoselective Coupling of Alkynes to 1,3- and 1,4-Dicarbonyl Systems. J Am Chem Soc. 2017 09 13; 139(36):12374-12377.
Kier MJ, Leon RM, O'Rourke NF, Rheingold AL, Micalizio GC. PMID: 28844136; PMCID: PMC5600187.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
-
The Development of Alkoxide-Directed Metallacycle-Mediated Annulative Cross-Coupling Chemistry. Isr J Chem. 2017 Apr; 57(3-4):228-238.
Micalizio GC, Mizoguchi H. PMID: 28652644; PMCID: PMC5482546.
View in:
PubMed Mentions:
12
-
Synthesis of Angularly Substituted trans-Fused Decalins through a Metallacycle-Mediated Annulative Cross-Coupling Cascade. Angew Chem Int Ed Engl. 2016 10 10; 55(42):13099-13103.
Mizoguchi H, Micalizio GC. PMID: 27634059; PMCID: PMC5056368.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
-
Metallacycle-Mediated Cross-Coupling in Natural Product Synthesis. Tetrahedron. 2016 11 10; 72(45):7093-7123.
O'Rourke NF, Kier MJ, Micalizio GC. PMID: 27765997; PMCID: PMC5067085.
View in:
PubMed Mentions:
12 Fields:
-
Acceleration of metallacycle-mediated alkyne-alkyne cross-coupling with TMSCl. Tetrahedron Lett. 2016 Aug 24; 57(34):3848-3850.
Cassidy JS, Mizoguchi H, Micalizio GC. PMID: 27713588; PMCID: PMC5046837.
View in:
PubMed Mentions:
3 Fields:
-
Synthesis of the Cortistatin Pentacyclic Core by Alkoxide-Directed Metallacycle-Mediated Annulative Cross-Coupling. Org Lett. 2016 06 03; 18(11):2624-7.
Aquino C, Greszler SN, Micalizio GC. PMID: 27193994; PMCID: PMC4892975.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
-
Cyclopropenes in Metallacycle-Mediated Cross-Coupling with Alkynes: Convergent Synthesis of Highly Substituted Vinylcyclopropanes. Org Lett. 2016 Mar 18; 18(6):1250-3.
O'Rourke NF, Micalizio GC. PMID: 26987882; PMCID: PMC4882924.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Synthesis of Neurotrophic Seco-prezizaane Sesquiterpenes (1R,10S)-2-Oxo-3,4-dehydroneomajucin, (2S)-Hydroxy-3,4-dehydroneomajucin, and (-)-Jiadifenin. J Am Chem Soc. 2016 Feb 03; 138(4):1150-3.
Cheng X, Micalizio GC. PMID: 26785051; PMCID: PMC4879688.
View in:
PubMed Mentions:
16 Fields:
Translation:
Cells
-
LiOOt-Bu as a terminal oxidant in a titanium alkoxide-mediated [2+2+2] reaction cascade. Tetrahedron Lett. 2015 Jun 03; 56(23):3357-3359.
Kim WS, Aquino C, Mizoguchi H, Micalizio GC. PMID: 26097265; PMCID: PMC4469278.
View in:
PubMed Mentions:
8 Fields:
-
Synthesis of Highly Functionalized Decalins via Metallacycle-Mediated Cross-Coupling. J Am Chem Soc. 2015 May 27; 137(20):6624-8.
Mizoguchi H, Micalizio GC. PMID: 25930967; PMCID: PMC4882187.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
-
Reaction design, discovery, and development as a foundation to function-oriented synthesis. Acc Chem Res. 2015 Mar 17; 48(3):663-73.
Micalizio GC, Hale SB. PMID: 25668752; PMCID: PMC4363280.
View in:
PubMed Mentions:
9 Fields:
Translation:
Cells
-
An annulation reaction for the synthesis of cross-conjugated triene-containing hydroindanes from acyclic precursors. Org Lett. 2014 Oct 03; 16(19):5144-7.
Cheng X, Micalizio GC. PMID: 25216381; PMCID: PMC4184447.
View in:
PubMed Mentions:
9 Fields:
Translation:
Cells
-
Synthesis of angularly substituted trans-fused hydroindanes by convergent coupling of acyclic precursors. J Am Chem Soc. 2014 Jun 11; 136(23):8209-12.
Jeso V, Aquino C, Cheng X, Mizoguchi H, Nakashige M, Micalizio GC. PMID: 24856045; PMCID: PMC4063191.
View in:
PubMed Mentions:
19 Fields:
Translation:
Cells
-
Synthesis of C11-Desmethoxy Soraphen A1α: A natural product analog that inhibits acetyl-CoA carboxylase. ACS Med Chem Lett. 2013 Dec 12; 4(12):1244-1248.
Canterbury DP, Scott KE, Kubo O, Jansen R, Cleveland JL, Micalizio GC. PMID: 24639892; PMCID: PMC3951358.
View in:
PubMed Mentions:
3
-
Characterization of T-5 N-oxide formation as the first highly selective measure of CYP3A5 activity. Drug Metab Dispos. 2014 Mar; 42(3):334-42.
Li X, Jeso V, Heyward S, Walker GS, Sharma R, Micalizio GC, Cameron MD. PMID: 24335391; PMCID: PMC3935135.
View in:
PubMed Mentions:
11 Fields:
-
Stereochemical lability of azatitanacyclopropanes: dynamic kinetic resolution in reductive cross-coupling reactions with allylic alcohols. Chem Commun (Camb). 2013 Oct 09; 49(78):8857-9.
Yang D, Micalizio GC. PMID: 23963189; PMCID: PMC4012230.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Decoding split and pool combinatorial libraries with electron-transfer dissociation tandem mass spectrometry. J Am Soc Mass Spectrom. 2013 Jul; 24(7):1026-36.
Sarkar M, Pascal BD, Steckler C, Aquino C, Micalizio GC, Kodadek T, Chalmers MJ. PMID: 23636859; PMCID: PMC4455952.
View in:
PubMed Mentions:
13 Fields:
Translation:
Cells
-
Synthesis and SAR of Lehualide B: a marine-derived natural product with potent anti-multiple myeloma activity. ACS Chem Biol. 2013; 8(6):1241-52.
Jeso V, Yang C, Cameron MD, Cleveland JL, Micalizio GC. PMID: 23547759; PMCID: PMC3758376.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Synthesis of benzoquinone ansamycin-inspired macrocyclic lactams from shikimic acid. Angew Chem Int Ed Engl. 2013 Apr 26; 52(18):4800-4.
Jeso V, Iqbal S, Hernandez P, Cameron MD, Park H, LoGrasso PV, Micalizio GC. PMID: 23554224.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Asymmetric synthesis: Relay catalysis at a boron centre. Nature. 2013 Feb 14; 494(7436):179-81.
Jeso V, Micalizio GC. PMID: 23407532.
View in:
PubMed Mentions: Fields:
-
Synthesis of the C1-C26 hexacyclic subunit of pectenotoxin 2. Org Lett. 2012 Nov 16; 14(22):5748-51.
Kubo O, Canterbury DP, Micalizio GC. PMID: 23101680; PMCID: PMC3500424.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Synthesis of alkaloid (-)-205B via stereoselective reductive cross-coupling and intramolecular [3+2] cycloaddition. J Am Chem Soc. 2012 Sep 19; 134(37):15237-40.
Yang D, Micalizio GC. PMID: 22957796; PMCID: PMC3470905.
View in:
PubMed Mentions:
11 Fields:
Translation:
Cells
-
Convergent synthesis of deoxypropionates. Angew Chem Int Ed Engl. 2012 May 21; 51(21):5152-6.
Diez PS, Micalizio GC. PMID: 22488893; PMCID: PMC3463508.
View in:
PubMed Mentions:
9 Fields:
-
Asymmetric synthesis of dihydroindanes by convergent alkoxide-directed metallacycle-mediated bond formation. J Am Chem Soc. 2012 Feb 08; 134(5):2766-74.
Greszler SN, Reichard HA, Micalizio GC. PMID: 22235773; PMCID: PMC3275653.
View in:
PubMed Mentions:
24 Fields:
Translation:
Cells
-
Three-component coupling sequence for the regiospecific synthesis of substituted pyridines. J Am Chem Soc. 2012 Jan 18; 134(2):1352-6.
Chen MZ, Micalizio GC. PMID: 22103772; PMCID: PMC3262091.
View in:
PubMed Mentions:
17 Fields:
Translation:
Cells
-
A biomimetic polyketide-inspired approach to small-molecule ligand discovery. Nat Chem. 2011 Nov 20; 4(2):99-104.
Aquino C, Sarkar M, Chalmers MJ, Mendes K, Kodadek T, Micalizio GC. PMID: 22270625; PMCID: PMC3266625.
View in:
PubMed Mentions:
38 Fields:
-
Convergent synthesis and discovery of a natural product-inspired paralog-selective Hsp90 inhibitor. Org Lett. 2011 Oct 07; 13(19):5108-11.
Jeso V, Cherry L, Macklin TK, Pan SC, LoGrasso PV, Micalizio GC. PMID: 21866939.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
-
Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain. Nat Chem. 2011 Jun; 3(6):449-53.
Tarselli MA, Raehal KM, Brasher AK, Streicher JM, Groer CE, Cameron MD, Bohn LM, Micalizio GC. PMID: 21602859.
View in:
PubMed Mentions:
14 Fields:
Translation:
Animals
-
Convergent and stereodivergent synthesis of complex 1-aza-7-oxabicyclo[2.2.1]heptanes. J Am Chem Soc. 2011 Jun 22; 133(24):9216-9.
Yang D, Micalizio GC. PMID: 21604673; PMCID: PMC3116711.
View in:
PubMed Mentions:
7 Fields:
-
Generation of quaternary centers by reductive cross-coupling: shifting of regioselectivity in a subset of allylic alcohol-based coupling reactions. Tetrahedron Lett. 2011 Apr 27; 52(17):2144-2147.
Yang D, Belardi JK, Micalizio GC. PMID: 21666832; PMCID: PMC3110011.
View in:
PubMed Mentions:
2 Fields:
-
A convergent route to the CDEF-tetracycle of pectenotoxin-2. Org Lett. 2011 May 06; 13(9):2384-7.
Canterbury DP, Micalizio GC. PMID: 21476517; PMCID: PMC3156112.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Metallacycle-Mediated Cross-Coupling with Substituted and Electronically Unactivated Alkenes. Chem Sci. 2011; 4(2):573-589.
Reichard HA, Micalizio GC. PMID: 21436986; PMCID: PMC3061465.
View in:
PubMed Mentions:
17
-
Preparation of stereodefined homoallylic amines from the reductive cross-coupling of allylic alcohols with imines. J Org Chem. 2010 Dec 03; 75(23):8048-59.
Chen MZ, McLaughlin M, Takahashi M, Tarselli MA, Yang D, Umemura S, Micalizio GC. PMID: 21069994; PMCID: PMC2993781.
View in:
PubMed Mentions:
13 Fields:
Translation:
Cells
-
Total synthesis of lehualide B by allylic alcohol-alkyne reductive cross-coupling. J Am Chem Soc. 2010 Aug 25; 132(33):11422-4.
Jeso V, Micalizio GC. PMID: 20681603; PMCID: PMC2923668.
View in:
PubMed Mentions:
14 Fields:
Translation:
Cells
-
Chemoselective reductive cross-coupling of 1,5-diene-3-ols with alkynes: a facile entry to stereodefined skipped trienes. J Am Chem Soc. 2010 Jul 21; 132(28):9576-8.
Diez PS, Micalizio GC. PMID: 20586460; PMCID: PMC2912438.
View in:
PubMed Mentions:
11 Fields:
-
The regio- and stereochemical course of reductive cross-coupling reactions between 1,3-disubstituted allenes and vinylsilanes: Synthesis of (Z)-dienes. Tetrahedron. 2010 Jun 26; 66(26):4775-4783.
Barlan AU, Micalizio GC. PMID: 24031099; PMCID: PMC3769195.
View in:
PubMed Mentions:
3 Fields:
-
Polyketide assembly by alkene-alkyne reductive cross-coupling: spiroketals through the union of homoallylic alcohols. J Am Chem Soc. 2010 Jun 09; 132(22):7602-4.
Canterbury DP, Micalizio GC. PMID: 20476790; PMCID: PMC2892691.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
-
Convergent and stereospecific synthesis of complex skipped polyenes and polyunsaturated fatty acids. Nat Chem. 2010 Aug; 2(8):638-43.
Macklin TK, Micalizio GC. PMID: 20651725; PMCID: PMC2909609.
View in:
PubMed Mentions:
19 Fields:
Translation:
Cells
-
Concerning the potential reversibility of carbometalation in alkoxide-directed Ti(Oi-Pr)4-mediated reductive cross-coupling of homoallylic alcohols with aromatic imines. Chem Commun (Camb). 2010 May 21; 46(19):3336-8.
Takahashi M, Micalizio GC. PMID: 20379585; PMCID: PMC3023109.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Regioselective Reductive Cross-Coupling Reactions of Unsymmetrical Alkynes. European J Org Chem. 2010 Jan; 2010(3):391-409.
Reichard HA, McLaughlin M, Chen MZ, Micalizio GC. PMID: 24634606; PMCID: PMC3951371.
View in:
PubMed Mentions:
35
-
A convergent stereoselective synthesis of quinolizidines and indolizidines: chemoselective coupling of 2-hydroxymethyl-substituted allylic silanes with imines. J Am Chem Soc. 2009 Dec 09; 131(48):17548-9.
Yang D, Micalizio GC. PMID: 19950989; PMCID: PMC2818501.
View in:
PubMed Mentions:
13 Fields:
-
Convergent synthesis of stereodefined exo-alkylidene-gamma-lactams from beta-halo allylic alcohols. Org Lett. 2009 Dec 03; 11(23):5402-5.
Umemura S, McLaughlin M, Micalizio GC. PMID: 19877599; PMCID: PMC2787655.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
-
Convergent synthesis of piperidines by the union of conjugated alkynes with imines: a unique regioselective bond construction for heterocycle synthesis. Org Lett. 2009 Nov 05; 11(21):4982-5.
Chen MZ, Micalizio GC. PMID: 19817447; PMCID: PMC2783831.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
-
Aliphatic imines in titanium-mediated reductive cross-coupling: unique reactivity of Ti(O-i-Pr)4/n-BuLi. Org Lett. 2009 Oct 15; 11(20):4596-9.
Tarselli MA, Micalizio GC. PMID: 19810765; PMCID: PMC2818175.
View in:
PubMed Mentions:
18 Fields:
Translation:
Cells
-
Stereoselective synthesis of trisubstituted (E,E)-1,3-dienes by the site-selective reductive cross-coupling of internal alkynes with terminal alkynes: a fragment coupling reaction for natural product synthesis. J Org Chem. 2009 Oct 02; 74(19):7211-9.
Perez LJ, Shimp HL, Micalizio GC. PMID: 19722544.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
-
Total synthesis and structure elucidation of (+)-phorbasin C. J Am Chem Soc. 2009 Feb 04; 131(4):1392-3.
Macklin TK, Micalizio GC. PMID: 19173665.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
-
Complex allylation by the direct cross-coupling of imines with unactivated allylic alcohols. Angew Chem Int Ed Engl. 2009; 48(20):3648-52.
Takahashi M, McLaughlin M, Micalizio GC. PMID: 19360820; PMCID: PMC3028933.
View in:
PubMed Mentions:
20 Fields:
-
Conversion of allylic alcohols to stereodefined trisubstituted alkenes: a complementary process to the Claisen rearrangement. J Am Chem Soc. 2008 Dec 17; 130(50):16870-2.
Belardi JK, Micalizio GC. PMID: 19053421; PMCID: PMC2732435.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
-
Allene-alkyne cross-coupling for stereoselective synthesis of substituted 1,4-dienes and cross-conjugated trienes. Tetrahedron. 2008 Apr 14; 64(4):3437-3445.
Shimp HL, Hare A, McLaughlin M, Micalizio GC. PMID: 18985173; PMCID: PMC2577592.
View in:
PubMed Mentions:
10 Fields:
-
Regio- and Stereoselective Direct Cross-Coupling of Aromatic Imines with Allenic Alcohols. Synlett. 2008 Mar 01; 2008(5):735-738.
McLaughlin M, Shimp HL, Navarro R, Micalizio GC. PMID: 25678759; PMCID: PMC4323354.
View in:
PubMed Mentions:
10
-
Total synthesis of macbecin I. Angew Chem Int Ed Engl. 2008; 47(21):4005-8.
Belardi JK, Micalizio GC. PMID: 18404757.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
-
Total synthesis of callystatin a by titanium-mediated reductive alkyne-alkyne cross-coupling. Angew Chem Int Ed Engl. 2008; 47(41):7837-40.
Reichard HA, Rieger JC, Micalizio GC. PMID: 18767199.
View in:
PubMed Mentions:
9 Fields:
Translation:
Cells
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Synthesis of substituted 1,4-dienes by direct alkylation of allylic alcohols. J Am Chem Soc. 2007 Dec 12; 129(49):15112-3.
Kolundzic F, Micalizio GC. PMID: 18004854; PMCID: PMC2732430.
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PubMed Mentions:
25 Fields:
Translation:
Cells
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An alkoxide-directed alkyne-allene cross-coupling for stereoselective synthesis of 1,4-dienes. Chem Commun (Camb). 2007 Nov 21; (43):4531-3.
Shimp HL, Micalizio GC. PMID: 17971979; PMCID: PMC4319186.
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PubMed Mentions:
9 Fields:
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Regio- and stereoselective cross-coupling of substituted olefins and imines. A convergent stereoselective synthesis of saturated 1,5-amino-alcohols and substituted piperidines. J Am Chem Soc. 2007 Jun 20; 129(24):7514-6.
Takahashi M, Micalizio GC. PMID: 17530760; PMCID: PMC2732432.
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17 Fields:
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An alkoxide-directed intermolecular [2+2+1] annulation: a three-component coupling reaction for the synthesis of tetrasubstituted alpha,beta-unsaturated gamma-lactams. Angew Chem Int Ed Engl. 2007; 46(21):3912-4.
McLaughlin M, Takahashi M, Micalizio GC. PMID: 17427164; PMCID: PMC4313383.
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PubMed Mentions:
14 Fields:
Translation:
Cells
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A site- and stereoselective intermolecular alkene-alkyne coupling process. Angew Chem Int Ed Engl. 2007; 46(9):1440-3.
Reichard HA, Micalizio GC. PMID: 17221894.
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PubMed Mentions:
20 Fields:
Translation:
Cells
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Studies on the syntheses of benzoquinone ansamycin antibiotics. Syntheses of the C5-C15 subunits of macbecin I, geldanamycin, and herbimycin A. Org Lett. 2006 May 25; 8(11):2409-12.
Belardi JK, Micalizio GC. PMID: 16706538.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Studies in macrolide antibiotic synthesis: the role of tethered alkoxides in titanium alkoxide-mediated regioselective reductive coupling reactions. Org Lett. 2006 Mar 16; 8(6):1181-4.
Bahadoor AB, Micalizio GC. PMID: 16524298.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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An alkoxide-directed carbometalation of internal alkynes. J Am Chem Soc. 2006 Mar 08; 128(9):2764-5.
Ryan J, Micalizio GC. PMID: 16506731.
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PubMed Mentions:
28 Fields:
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Group 4 metals in polyketide synthesis: a convergent strategy for the synthesis of polypropionate-derived (E,E)-trisubstituted 1,3-dienes. Org Lett. 2005 Oct 27; 7(22):5111-4.
Shimp HL, Micalizio GC. PMID: 16235970.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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A pentenyl dianion-based strategy for convergent synthesis of ene-1,5-diols. J Am Chem Soc. 2005 Mar 23; 127(11):3694-5.
Bahadoor AB, Flyer A, Micalizio GC. PMID: 15771493.
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PubMed Mentions:
13 Fields:
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Enantio- and diastereoselective synthesis of cyclic beta-hydroxy allylsilanes via sequential aldehyde gamma-silylallylboration and ring-closing metathesis reactions. Org Lett. 2003 May 15; 5(10):1693-6.
Heo JN, Micalizio GC, Roush WR. PMID: 12735754.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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An alkynylboronic ester annulation: development of synthetic methods for application to diversity-oriented organic synthesis. Angew Chem Int Ed Engl. 2002 Sep 02; 41(17):3272-6.
Micalizio GC, Schreiber SL. PMID: 12207413.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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A boronic ester annulation strategy for diversity-oriented organic synthesis. Angew Chem Int Ed Engl. 2002 Jan 04; 41(1):152-4.
Micalizio GC, Schreiber SL. PMID: 12491469.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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Studies on the synthesis of pectenotoxin II: synthesis of a C(11)-C(26) fragment precursor via [3 + 2]-annulation reactions of chiral allylsilanes. Org Lett. 2001 Jun 14; 3(12):1949-52.
Micalizio GC, Roush WR. PMID: 11405752.
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PubMed Mentions:
14 Fields:
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Synthesis of the C(29)-C(45) bis-pyran subunit (E-F) of spongistatin 1 (Altohyrtin A). J Org Chem. 2000 Dec 15; 65(25):8730-6.
Micalizio GC, Pinchuk AN, Roush WR. PMID: 11112596.
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PubMed Mentions:
3 Fields:
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A three-component coupling strategy for tetrahydrofuran synthesis: application of the diisopropyl tartrate modified (E)-gamma-(dimethylphenylsilyl)allylboronate as an alpha,gamma-allyl dianion equivalent. Org Lett. 2000 Feb 24; 2(4):461-4.
Micalizio GC, Roush WR. PMID: 10814351.
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PubMed Mentions:
12 Fields: