Douglas Keith Trask

Title(s)Clinical Professor, Otolaryngology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-5753
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    Collapse Research 
    Collapse Research Activities and Funding
    Reactive Oxygen Species Inhibition of Oral Cancer Growth
    NIH K08CA104631Sep 16, 2005 - Aug 31, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Influenza vaccine format mediates distinct cellular and antibody responses in human immune organoids. Immunity. 2023 08 08; 56(8):1910-1926.e7. Kastenschmidt JM, Sureshchandra S, Jain A, Hernandez-Davies JE, de Assis R, Wagoner ZW, Sorn AM, Mitul MT, Benchorin AI, Levendosky E, Ahuja G, Zhong Q, Trask D, Boeckmann J, Nakajima R, Jasinskas A, Saligrama N, Davies DH, Wagar LE. PMID: 37478854; PMCID: PMC10433940.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    2. Upper Airway Stimulation versus Untreated Comparators in Positive Airway Pressure Treatment-Refractory Obstructive Sleep Apnea. Ann Am Thorac Soc. 2020 12; 17(12):1610-1619. Mehra R, Steffen A, Heiser C, Hofauer B, Withrow K, Doghramji K, Boon M, Huntley C, Soose RJ, Stevens S, Larsen C, Maurer JT, Waters T, Walia HK, Kominsky AH, Trask D, Schwab RJ, Thaler ER, Strollo PJ. PMID: 32663043.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    3. Preoperative Predictors of Response to Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea. Otolaryngol Head Neck Surg. 2020 Mar; 162(3):400-407. Xiao R, Trask DK, Kominsky AH. PMID: 31959054.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    4. Tachyphylaxis and Dependence in Pharmacotherapy for Unexplained Chronic Cough. Otolaryngol Head Neck Surg. 2018 10; 159(4):705-711. Bowen AJ, Huang TL, Nowacki AS, Trask D, Kaltenbach J, Taliercio R, Benninger MS, Milstein CF, Bryson PC. PMID: 30016197.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Short- and Long-term Effects of Neuromodulators for Unexplained Chronic Cough. Otolaryngol Head Neck Surg. 2018 09; 159(3):508-515. Bowen AJ, Nowacki AS, Contrera K, Trask D, Kaltenbach J, Milstein CF, Adessa M, Benninger MS, Taliercio R, Bryson PC. PMID: 29634404.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    6. Uvulopalatopharyngoplasty vs CN XII stimulation for treatment of obstructive sleep apnea: A single institution experience. Am J Otolaryngol. 2018 May - Jun; 39(3):266-270. Shah J, Russell JO, Waters T, Kominsky AH, Trask D. PMID: 29540289.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    7. Voice and swallowing outcomes following hypoglossal nerve stimulation for obstructive sleep apnea. Am J Otolaryngol. 2018 Mar - Apr; 39(2):122-126. Bowen AJ, Nowacki AS, Kominsky AH, Trask DK, Benninger MS, Bryson PC. PMID: 29277289.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    8. Celecoxib Versus Placebo in Tonsillectomy: A Prospective, Randomized, Double-Blind Placebo-Controlled Trial. Ann Otol Rhinol Laryngol. 2016 Oct; 125(10):785-800. Van Daele DJ, Bodeker KL, Trask DK. PMID: 27357971.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Acute Rhinosinusitis: Prescription Patterns in a Real-World Setting. Otolaryngol Head Neck Surg. 2016 05; 154(5):957-62. Benninger MS, Holy CE, Trask DK. PMID: 26932952.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Detection of metastatic head and neck squamous cell carcinoma using the relative expression of tissue-specific mir-205. Transl Oncol. 2008 Dec; 1(4):202-8. Fletcher AM, Heaford AC, Trask DK. PMID: 19043531; PMCID: PMC2582169.
      View in: PubMed   Mentions: 33  
    11. Coblation-assisted lingual tonsillectomy for dysphagia secondary to tongue base hypertrophy. Ann Otol Rhinol Laryngol. 2008 Jul; 117(7):506-9. Bock JM, Trask DK. PMID: 18700425.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Modulation of cellular invasion by VEGF-C expression in squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg. 2008 Apr; 134(4):355-62. Bock JM, Sinclair LL, Bedford NS, Jackson RE, Lee JH, Trask DK. PMID: 18427000.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    13. Relative non-steroidal anti-inflammatory drug (NSAID) antiproliferative activity is mediated through p21-induced G1 arrest and E2F inhibition. Mol Carcinog. 2007 Oct; 46(10):857-64. Bock JM, Menon SG, Goswami PC, Sinclair LL, Bedford NS, Domann FE, Trask DK. PMID: 17415779.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    14. Celecoxib toxicity is cell cycle phase specific. Cancer Res. 2007 Apr 15; 67(8):3801-8. Bock JM, Menon SG, Sinclair LL, Bedford NS, Goswami PC, Domann FE, Trask DK. PMID: 17440094.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    15. Skull base thrombotic mycosis. Ear Nose Throat J. 2007 Mar; 86(3):137. Wilkinson EP, Robinson RA, Trask DK. PMID: 17427771.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Differential activity of sulindac metabolites against squamous cell carcinoma of the head and neck is mediated by p21waf1/cip1 induction and cell cycle inhibition. Cancer Biol Ther. 2007 Jan; 6(1):30-9. Bock JM, Menon SG, Goswami PC, Sinclair LL, Bedford NS, Jackson RE, Trask DK. PMID: 17172818.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    17. Transnasal, endoscopic vocal fold augmentation. Laryngoscope. 2005 Dec; 115(12):2262-5. Trask DK, Shellenberger DL, Hoffman HT. PMID: 16369177.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    18. Long-term quality of life for surgical and nonsurgical treatment of head and neck cancer. Arch Otolaryngol Head Neck Surg. 2005 Oct; 131(10):879-85. El-Deiry M, Funk GF, Nalwa S, Karnell LH, Smith RB, Buatti JM, Hoffman HT, Clamon GH, Graham SM, Trask DK, Dornfeld KJ, Yao M. PMID: 16230590.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    19. Oral melanoacanthoma: a case report, a review of the literature, and a new treatment option. Ann Otol Rhinol Laryngol. 2005 Sep; 114(9):677-80. Andrews BT, Trask DK. PMID: 16240929.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    20. Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL. Mol Cancer Ther. 2005 Jul; 4(7):1096-104. Bauer JA, Trask DK, Kumar B, Los G, Castro J, Lee JS, Chen J, Wang S, Bradford CR, Carey TE. PMID: 16020667.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    21. Molecular profiling and the identification of genes associated with metastatic oral cavity/pharynx squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2004 Mar; 130(3):295-302. Schmalbach CE, Chepeha DB, Giordano TJ, Rubin MA, Teknos TN, Bradford CR, Wolf GT, Kuick R, Misek DE, Trask DK, Hanash S. PMID: 15023835.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    22. Genetically targeted radiotherapy of head and neck squamous cell carcinoma using the sodium-iodide symporter (NIS). Head Neck. 2004 Mar; 26(3):265-71. Gaut AW, Niu G, Krager KJ, Graham MM, Trask DK, Domann FE. PMID: 14999802.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    23. Validation of tissue microarrays using p53 immunohistochemical studies of squamous cell carcinoma of the larynx. Mod Pathol. 2003 Dec; 16(12):1181-8. Griffin MC, Robinson RA, Trask DK. PMID: 14681317.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    24. Expression of Bcl-2 family proteins in advanced laryngeal squamous cell carcinoma: correlation with response to chemotherapy and organ preservation. Laryngoscope. 2002 Apr; 112(4):638-44. Trask DK, Wolf GT, Bradford CR, Fisher SG, Devaney K, Johnson M, Singleton T, Wicha M. PMID: 12150516.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    25. Presentation, treatment, and outcome of oral cavity cancer: a National Cancer Data Base report. Head Neck. 2002 Feb; 24(2):165-80. Funk GF, Karnell LH, Robinson RA, Zhen WK, Trask DK, Hoffman HT. PMID: 11891947.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
    26. National survey of head and neck verrucous carcinoma: patterns of presentation, care, and outcome. Cancer. 2001 Jul 01; 92(1):110-20. Koch BB, Trask DK, Hoffman HT, Karnell LH, Robinson RA, Zhen W, Menck HR, Commission on Cancer, American College of Surgeons, American Cancer Society. PMID: 11443616.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    27. Silicone oil in the repair of complex retinal detachments. A prospective observational multicenter study. Ophthalmology. 1998 Sep; 105(9):1587-97. Azen SP, Scott IU, Flynn HW, Lai MY, Topping TM, Benati L, Trask DK, Rogus LA. PMID: 9754162.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCTClinical Trials
    28. Silicone oil in repair of retinal detachments caused by necrotizing retinitis in HIV infection. Arch Ophthalmol. 1995 Nov; 113(11):1401-9. Davis JL, Serfass MS, Lai MY, Trask DK, Azen SP. PMID: 7487601.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    29. Tumor progression in four mammary epithelial cell lines derived from the same patient. Cancer Res. 1990 Nov 15; 50(22):7351-7. Band V, Zajchowski D, Swisshelm K, Trask D, Kulesa V, Cohen C, Connolly J, Sager R. PMID: 1977518.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    30. Inhibition of potentially lethal DNA damage repair in human tumor cells by beta-lapachone, an activator of topoisomerase I. Cancer Res. 1989 Feb 01; 49(3):605-12. Boothman DA, Trask DK, Pardee AB. PMID: 2535961.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
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