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Wodarz, Dominik Franz Xave

TitleProfessor and Vice Chair
InstitutionUniversity of California, Irvine
DepartmentEcology & Evolutionary Biology
Address419 Steinhaus Hall
Zot 2525
CA 92697
Phone(949) 824-2531
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    Collapse Research 
    Collapse Research Activities and Funding
    Aspirin and Cancer Prevention in Lynch Syndrome: From Cell to Population Data
    NIH/NCI U01CA187956Sep 23, 2014 - Jun 30, 2019
    Role: Co-Principal Investigator
    Viruis Dynamics and Multiple Infection of Cells: Computational and Experimental A
    NIH/NIAID R01AI093998Aug 3, 2011 - Jul 31, 2015
    Role: Principal Investigator
    Mathematical Models of Programmed CTL Proliferation
    NIH/NIAID R01AI058153Jul 1, 2005 - Mar 31, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wodarz D, Newell AC, Komarova NL. Passenger mutations can accelerate tumour suppressor gene inactivation in cancer evolution. J R Soc Interface. 2018 Jun; 15(143). PMID: 29875280.
      View in: PubMed
    2. Wodarz D. Effect of cellular de-differentiation on the dynamics and evolution of tissue and tumor cells in mathematical models with feedback regulation. J Theor Biol. 2018 Jul 07; 448:86-93. PMID: 29605227.
      View in: PubMed
    3. Harris D, Wodarz D, Komarova NL. Spatial evolution of regularization in learned behavior of animals. Math Biosci. 2018 May; 299:103-116. PMID: 29550299.
      View in: PubMed
    4. Wodarz D, Goel A, Komarova NL. Effect of cell cycle duration on somatic evolutionary dynamics. Evol Appl. 2017 Dec; 10(10):1121-1129. PMID: 29151865.
      View in: PubMed
    5. Wodarz D, Goel A, Boland CR, Komarova NL. Effect of aspirin on tumour cell colony formation and evolution. J R Soc Interface. 2017 Sep; 14(134). PMID: 28878032.
      View in: PubMed
    6. Wodarz D, Rodriguez-Brenes I. Early Stochastic Dynamics in Human Cytomegalovirus Infection. J Virol. 2017 09 15; 91(18). PMID: 28839088.
      View in: PubMed
    7. Wodarz D, Levy DN. Pyroptosis, superinfection, and the maintenance of the latent reservoir in HIV-1 infection. Sci Rep. 2017 Jun 19; 7(1):3834. PMID: 28630490.
      View in: PubMed
    8. Zhang J, Fleischman AG, Wodarz D, Komarova NL. Determining the role of inflammation in the selection of JAK2 mutant cells in myeloproliferative neoplasms. J Theor Biol. 2017 Jul 21; 425:43-52. PMID: 28501635.
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    9. Rodriguez-Brenes IA, Kurtova AV, Lin C, Lee YC, Xiao J, Mims M, Chan KS, Wodarz D. Cellular Hierarchy as a Determinant of Tumor Sensitivity to Chemotherapy. Cancer Res. 2017 05 01; 77(9):2231-2241. PMID: 28235762.
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    10. Zumwalt TJ, Wodarz D, Komarova NL, Toden S, Turner J, Cardenas J, Burn J, Chan AT, Boland CR, Goel A. Aspirin-Induced Chemoprevention and Response Kinetics Are Enhanced by PIK3CA Mutations in Colorectal Cancer Cells. Cancer Prev Res (Phila). 2017 Mar; 10(3):208-218. PMID: 28154202.
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    11. Burger JA, Li KW, Keating MJ, Sivina M, Amer AM, Garg N, Ferrajoli A, Huang X, Kantarjian H, Wierda WG, O'Brien S, Hellerstein MK, Turner SM, Emson CL, Chen SS, Yan XJ, Wodarz D, Chiorazzi N. Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib. JCI Insight. 2017 Jan 26; 2(2):e89904. PMID: 28138560.
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    12. Rodriguez-Brenes IA, Hofacre A, Fan H, Wodarz D. Complex Dynamics of Virus Spread from Low Infection Multiplicities: Implications for the Spread of Oncolytic Viruses. PLoS Comput Biol. 2017 Jan; 13(1):e1005241. PMID: 28107341.
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    13. Law KM, Komarova NL, Yewdall AW, Lee RK, Herrera OL, Wodarz D, Chen BK. In Vivo HIV-1 Cell-to-Cell Transmission Promotes Multicopy Micro-compartmentalized Infection. Cell Rep. 2016 06 21; 15(12):2771-83. PMID: 27292632.
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    14. Wodarz D. Computational modeling approaches to the dynamics of oncolytic viruses. Wiley Interdiscip Rev Syst Biol Med. 2016 05; 8(3):242-52. PMID: 27001049; PMCID: PMC4896310 [Available on 05/01/17].
    15. Stipp SR, Iniguez A, Wan F, Wodarz D. Timing of CD8 T cell effector responses in viral infections. R Soc Open Sci. 2016 Feb; 3(2):150661. PMID: 26998338; PMCID: PMC4785989.
    16. Rodriguez-Brenes IA, Wodarz D. Telomeres open a window on stem cell division. Elife. 2016 Jan 25; 5:e12481. PMID: 26807592; PMCID: PMC4744181.
    17. Chan CN, Trinité B, Lee CS, Mahajan S, Anand A, Wodarz D, Sabbaj S, Bansal A, Goepfert PA, Levy DN. HIV-1 latency and virus production from unintegrated genomes following direct infection of resting CD4 T cells. Retrovirology. 2016 Jan 05; 13:1. PMID: 26728316; PMCID: PMC4700562.
    18. Rodriguez-Brenes IA, Wodarz D, Komarova NL. Quantifying replicative senescence as a tumor suppressor pathway and a target for cancer therapy. Sci Rep. 2015 Dec 09; 5:17660. PMID: 26647820; PMCID: PMC4673423.
    19. Rodriguez-Brenes IA, Wodarz D, Komarova NL. Characterizing inhibited tumor growth in stem-cell-driven non-spatial cancers. Math Biosci. 2015 Dec; 270(Pt A):135-41. PMID: 26344137.
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    20. Rodriguez-Brenes IA, Wodarz D. Preventing clonal evolutionary processes in cancer: Insights from mathematical models. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):8843-50. PMID: 26195751; PMCID: PMC4517241.
    21. Asatryan A, Wodarz D, Komarova NL. New virus dynamics in the presence of multiple infection. J Theor Biol. 2015 Jul 21; 377:98-109. PMID: 25908207.
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    22. Phan D, Wodarz D. Modeling multiple infection of cells by viruses: Challenges and insights. Math Biosci. 2015 Jun; 264:21-8. PMID: 25770053; PMCID: PMC4426218.
    23. Toden S, Okugawa Y, Jascur T, Wodarz D, Komarova NL, Buhrmann C, Shakibaei M, Boland CR, Goel A. Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer. Carcinogenesis. 2015 Mar; 36(3):355-67. PMID: 25653233; PMCID: PMC4400529.
    24. Wodarz D, Zauber AG. Cancer: Risk factors and random chances. Nature. 2015 Jan 29; 517(7536):563-4. PMID: 25631443.
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    25. Lau JW, Levy DN, Wodarz D. Contribution of HIV-1 genomes that do not integrate to the basic reproductive ratio of the virus. J Theor Biol. 2015 Feb 21; 367:222-229. PMID: 25496730.
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    26. Wodarz D. Modeling T cell responses to antigenic challenge. J Pharmacokinet Pharmacodyn. 2014 Oct; 41(5):415-29. PMID: 25269610; PMCID: PMC4210371.
    27. Komarova NL, Burger JA, Wodarz D. Evolution of ibrutinib resistance in chronic lymphocytic leukemia (CLL). Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38):13906-11. PMID: 25201956; PMCID: PMC4183279.
    28. Wodarz D, Chan CN, Trinité B, Komarova NL, Levy DN. On the laws of virus spread through cell populations. J Virol. 2014 Nov; 88(22):13240-8. PMID: 25187551; PMCID: PMC4249084.
    29. Wodarz D, Garg N, Komarova NL, Benjamini O, Keating MJ, Wierda WG, Kantarjian H, James D, O'Brien S, Burger JA. Kinetics of CLL cells in tissues and blood during therapy with the BTK inhibitor ibrutinib. Blood. 2014 Jun 26; 123(26):4132-5. PMID: 24829205; PMCID: PMC4123432.
    30. Wodarz D, Sorace R, Komarova NL. Dynamics of cellular responses to radiation. PLoS Comput Biol. 2014 Apr; 10(4):e1003513. PMID: 24722167; PMCID: PMC3983039.
    31. Komarova NL, Shahriyari L, Wodarz D. Complex role of space in the crossing of fitness valleys by asexual populations. J R Soc Interface. 2014 Jun 06; 11(95):20140014. PMID: 24671934; PMCID: PMC4006240.
    32. Rodriguez-Brenes IA, Komarova NL, Wodarz D. Cancer-associated mutations in healthy individuals: assessing the risk of carcinogenesis. Cancer Res. 2014 Mar 15; 74(6):1661-9. PMID: 24453004.
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    33. Wodarz D. Mathematical models of HIV replication and pathogenesis. Methods Mol Biol. 2014; 1184:563-81. PMID: 25048145.
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    34. Roy SM, Wodarz D. Tissue architecture, feedback regulation, and resilience to viral infection. J Theor Biol. 2014 Jan 07; 340:131-8. PMID: 24056215; PMCID: PMC4102259.
    35. Trinité B, Ohlson EC, Voznesensky I, Rana SP, Chan CN, Mahajan S, Alster J, Burke SA, Wodarz D, Levy DN. An HIV-1 replication pathway utilizing reverse transcription products that fail to integrate. J Virol. 2013 Dec; 87(23):12701-20. PMID: 24049167; PMCID: PMC3838139.
    36. Wodarz D, Komarova NL. Dependence of the firearm-related homicide rate on gun availability: a mathematical analysis. PLoS One. 2013; 8(7):e71606. PMID: 23923062; PMCID: PMC3724776.
    37. Wodarz D, Sun Z, Lau JW, Komarova NL. Nearest-neighbor interactions, habitat fragmentation, and the persistence of host-pathogen systems. Am Nat. 2013 Sep; 182(3):E94-E111. PMID: 23933732; PMCID: PMC4762454.
    38. Rodriguez-Brenes IA, Wodarz D, Komarova NL. Minimizing the risk of cancer: tissue architecture and cellular replication limits. J R Soc Interface. 2013 Sep 06; 10(86):20130410. PMID: 23825115; PMCID: PMC3730689.
    39. Rodriguez-Brenes IA, Komarova NL, Wodarz D. Tumor growth dynamics: insights into evolutionary processes. Trends Ecol Evol. 2013 Oct; 28(10):597-604. PMID: 23816268.
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    40. Wodarz D, Boland CR, Goel A, Komarova NL. Methylation kinetics and CpG-island methylator phenotype status in colorectal cancer cell lines. Biol Direct. 2013 Jun 11; 8:14. PMID: 23758948; PMCID: PMC3691599.
    41. Wodarz D. Evolutionary dynamics of giant viruses and their virophages. Ecol Evol. 2013 Jul; 3(7):2103-15. PMID: 23919155; PMCID: PMC3728950.
    42. Wodarz D. Computational modeling approaches to studying the dynamics of oncolytic viruses. Math Biosci Eng. 2013 Jun; 10(3):939-57. PMID: 23906157.
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    43. Rodriguez-Brenes IA, Wodarz D, Komarova NL. Stem cell control, oscillations, and tissue regeneration in spatial and non-spatial models. Front Oncol. 2013; 3:82. PMID: 23596567; PMCID: PMC3625858.
    44. Komarova NL, Wodarz D. Virus dynamics in the presence of synaptic transmission. Math Biosci. 2013 Apr; 242(2):161-71. PMID: 23357287; PMCID: PMC4122664.
    45. Komarova NL, Levy DN, Wodarz D. Synaptic transmission and the susceptibility of HIV infection to anti-viral drugs. Sci Rep. 2013; 3:2103. PMID: 23811684; PMCID: PMC3696900.
    46. Komarova NL, Anghelina D, Voznesensky I, Trinité B, Levy DN, Wodarz D. Relative contribution of free-virus and synaptic transmission to the spread of HIV-1 through target cell populations. Biol Lett. 2013 Feb 23; 9(1):20121049. PMID: 23269844; PMCID: PMC3565528.
    47. Komarova NL, Urwin E, Wodarz D. Accelerated crossing of fitness valleys through division of labor and cheating in asexual populations. Sci Rep. 2012; 2:917. PMID: 23209877; PMCID: PMC3512085.
    48. Komarova NL, Levy DN, Wodarz D. Effect of synaptic transmission on viral fitness in HIV infection. PLoS One. 2012; 7(11):e48361. PMID: 23166585; PMCID: PMC3499495.
    49. Wodarz D, Hofacre A, Lau JW, Sun Z, Fan H, Komarova NL. Complex spatial dynamics of oncolytic viruses in vitro: mathematical and experimental approaches. PLoS Comput Biol. 2012; 8(6):e1002547. PMID: 22719239; PMCID: PMC3375216.
    50. Cummings KW, Levy DN, Wodarz D. Increased burst size in multiply infected cells can alter basic virus dynamics. Biol Direct. 2012 May 08; 7:16. PMID: 22569346; PMCID: PMC3482397.
    51. Roy SM, Wodarz D. Infection of HIV-specific CD4 T helper cells and the clonal composition of the response. J Theor Biol. 2012 Jul 07; 304:143-51. PMID: 22480435; PMCID: PMC4082790.
    52. Hofacre A, Wodarz D, Komarova NL, Fan H. Early infection and spread of a conditionally replicating adenovirus under conditions of plaque formation. Virology. 2012 Feb 05; 423(1):89-96. PMID: 22192628.
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    53. Rodriguez-Brenes IA, Komarova NL, Wodarz D. Evolutionary dynamics of feedback escape and the development of stem-cell-driven cancers. Proc Natl Acad Sci U S A. 2011 Nov 22; 108(47):18983-8. PMID: 22084071; PMCID: PMC3223454.
    54. Wodarz D, Levy DN. Effect of multiple infection of cells on the evolutionary dynamics of HIV in vivo: implications for host adaptation mechanisms. Exp Biol Med (Maywood). 2011 Aug; 236(8):926-37. PMID: 21768164.
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    55. Del Portillo A, Tripodi J, Najfeld V, Wodarz D, Levy DN, Chen BK. Multiploid inheritance of HIV-1 during cell-to-cell infection. J Virol. 2011 Jul; 85(14):7169-76. PMID: 21543479; PMCID: PMC3126592.
    56. Wodarz D, Levy DN. Effect of different modes of viral spread on the dynamics of multiply infected cells in human immunodeficiency virus infection. J R Soc Interface. 2011 Feb 06; 8(55):289-300. PMID: 20659927; PMCID: PMC3033025.
    57. Wodarz D. Heterogeneity in chronic myeloid leukaemia dynamics during imatinib treatment: role of immune responses. Proc Biol Sci. 2010 Jun 22; 277(1689):1875-80. PMID: 20147328; PMCID: PMC2871874.
    58. Komarova NL, Wodarz D. ODE models for oncolytic virus dynamics. J Theor Biol. 2010 Apr 21; 263(4):530-43. PMID: 20085772; PMCID: PMC2839021.
    59. Wodarz D, Levy DN. Multiple HIV-1 infection of cells and the evolutionary dynamics of cytotoxic T lymphocyte escape mutants. Evolution. 2009 Sep; 63(9):2326-39. PMID: 19486149.
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    60. Komarova NL, Wodarz D. Combination therapies against chronic myeloid leukemia: short-term versus long-term strategies. Cancer Res. 2009 Jun 01; 69(11):4904-10. PMID: 19458080.
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    61. Komarova NL, Katouli AA, Wodarz D. Combination of two but not three current targeted drugs can improve therapy of chronic myeloid leukemia. PLoS One. 2009; 4(2):e4423. PMID: 19204794; PMCID: PMC2635955.
    62. Wodarz D. Use of oncolytic viruses for the eradication of drug-resistant cancer cells. J R Soc Interface. 2009 Feb 06; 6(31):179-86. PMID: 18664430; PMCID: PMC2658788.
    63. Wodarz D, Komarova N. Towards predictive computational models of oncolytic virus therapy: basis for experimental validation and model selection. PLoS One. 2009; 4(1):e4271. PMID: 19180240; PMCID: PMC2629569.
    64. Wodarz D. Immunity and protection by live attenuated HIV/SIV vaccines. Virology. 2008 Sep 01; 378(2):299-305. PMID: 18586297; PMCID: PMC2613491.
    65. Wodarz D, Levy DN. Human immunodeficiency virus evolution towards reduced replicative fitness in vivo and the development of AIDS. Proc Biol Sci. 2007 Oct 07; 274(1624):2481-90. PMID: 17666377; PMCID: PMC2274968.
    66. Komarova NL, Wodarz D. Effect of cellular quiescence on the success of targeted CML therapy. PLoS One. 2007 Oct 03; 2(10):e990. PMID: 17912367; PMCID: PMC1991595.
    67. Komarova NL, Wodarz D. Stochastic modeling of cellular colonies with quiescence: an application to drug resistance in cancer. Theor Popul Biol. 2007 Dec; 72(4):523-38. PMID: 17915274.
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    68. Wodarz D, Sierro S, Klenerman P. Dynamics of killer T cell inflation in viral infections. J R Soc Interface. 2007 Jun 22; 4(14):533-43. PMID: 17251133; PMCID: PMC2373406.
    69. Wodarz D. Stem cell regulation and the development of blast crisis in chronic myeloid leukemia: Implications for the outcome of Imatinib treatment and discontinuation. Med Hypotheses. 2008; 70(1):128-36. PMID: 17566666.
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    70. Wodarz D, Komarova N. Can loss of apoptosis protect against cancer? Trends Genet. 2007 May; 23(5):232-7. PMID: 17382429.
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    71. Wodarz D. On the relative fitness of early and late stage Simian immunodeficiency virus isolates. Theor Popul Biol. 2007 Nov; 72(3):426-35. PMID: 17499829; PMCID: PMC4058051.
    72. Wodarz D, Hamer DH. Infection dynamics in HIV-specific CD4 T cells: does a CD4 T cell boost benefit the host or the virus? Math Biosci. 2007 Sep; 209(1):14-29. PMID: 17379260; PMCID: PMC4058052.
    73. Wodarz D. Effect of stem cell turnover rates on protection against cancer and aging. J Theor Biol. 2007 Apr 07; 245(3):449-58. PMID: 17178130.
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    74. Zurakowski R, Wodarz D. Model-driven approaches for in vitro combination therapy using ONYX-015 replicating oncolytic adenovirus. J Theor Biol. 2007 Mar 07; 245(1):1-8. PMID: 17095020; PMCID: PMC2712658.
    75. Wodarz D. Targeted cancer treatment: resisting arrest. Nat Med. 2006 Oct; 12(10):1125-6. PMID: 17024205.
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    76. Wodarz D. Ecological and evolutionary principles in immunology. Ecol Lett. 2006 Jun; 9(6):694-705. PMID: 16706914.
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    77. Wodarz D, Komarova NL. Emergence and prevention of resistance against small molecule inhibitors. Semin Cancer Biol. 2005 Dec; 15(6):506-14. PMID: 16154360.
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    78. Wodarz D, Thomsen AR. Effect of the CTL proliferation program on virus dynamics. Int Immunol. 2005 Sep; 17(9):1269-76. PMID: 16103027.
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    79. Komarova NL, Wodarz D. Drug resistance in cancer: principles of emergence and prevention. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9714-9. PMID: 15980154; PMCID: PMC1172248.
    80. Wodarz D, Anton-Culver H. Dynamical interactions between multiple cancers. Cell Cycle. 2005 Jun; 4(6):764-71. PMID: 15917665.
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    81. Wodarz D, Thomsen AR. Does programmed CTL proliferation optimize virus control? Trends Immunol. 2005 Jun; 26(6):305-10. PMID: 15922946.
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    82. Jansen VA, Altes HK, Funk GA, Wodarz D. Contrasting B cell- and T cell-based protective vaccines. J Theor Biol. 2005 May 07; 234(1):39-48. PMID: 15721034.
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    83. Wodarz D. Checkpoint genes, ageing, and the development of cancer. Oncogene. 2004 Oct 14; 23(47):7799-809. PMID: 15361848.
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    84. Wodarz D, Iwasa Y, Komarova NL. On the emergence of multifocal cancers. J Carcinog. 2004 Oct 01; 3(1):13. PMID: 15461783.
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    85. Wodarz D, Lloyd AL. Immune responses and the emergence of drug-resistant virus strains in vivo. Proc Biol Sci. 2004 Jun 07; 271(1544):1101-9. PMID: 15306358; PMCID: PMC1691709.
    86. Christensen JE, Wodarz D, Christensen JP, Thomsen AR. Perforin and IFN-gamma do not significantly regulate the virus-specific CD8+ T cell response in the absence of antiviral effector activity. Eur J Immunol. 2004 May; 34(5):1389-94. PMID: 15114672.
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    87. Komarova NL, Wodarz D. The optimal rate of chromosome loss for the inactivation of tumor suppressor genes in cancer. Proc Natl Acad Sci U S A. 2004 May 04; 101(18):7017-21. PMID: 15105448; PMCID: PMC406458.
    88. Wodarz D, Sasaki A. Apparent competition and recovery from infection. J Theor Biol. 2004 Apr 07; 227(3):403-12. PMID: 15019507.
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    89. Wodarz D. Correspondence re: L. M. Wein et al., validation and analysis of a mathematical model of a replication-competent oncolytic virus for cancer treatment: implications for virus design and delivery. Cancer Res., 63: 1317-1324, 2003. Cancer Res. 2003 Dec 01; 63(23):8554;author reply 8556-7. PMID: 14679025.
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    90. Komarova NL, Wodarz D. Evolutionary dynamics of mutator phenotypes in cancer: implications for chemotherapy. Cancer Res. 2003 Oct 15; 63(20):6635-42. PMID: 14583456.
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    91. Wodarz D. Mutants escape from killer T cells, invade population. Nat Med. 2003 Oct; 9(10):1254-5. PMID: 14520368.
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    92. Wodarz D. Evolution of immunological memory and the regulation of competition between pathogens. Curr Biol. 2003 Sep 16; 13(18):1648-52. PMID: 13678598.
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    93. Wodarz D. Hepatitis C virus dynamics and pathology: the role of CTL and antibody responses. J Gen Virol. 2003 Jul; 84(Pt 7):1743-50. PMID: 12810868.
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    94. Liu H, Andreansky S, Diaz G, Turner SJ, Wodarz D, Doherty PC. Quantitative analysis of long-term virus-specific CD8+-T-cell memory in mice challenged with unrelated pathogens. J Virol. 2003 Jul; 77(14):7756-63. PMID: 12829815; PMCID: PMC161950.
    95. Wodarz D, Jansen VA. A dynamical perspective of CTL cross-priming and regulation: implications for cancer immunology. Immunol Lett. 2003 May 01; 86(3):213-27. PMID: 12706524.
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    96. Komarova NL, Barnes E, Klenerman P, Wodarz D. Boosting immunity by antiviral drug therapy: a simple relationship among timing, efficacy, and success. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1855-60. PMID: 12574516; PMCID: PMC149923.
    97. Wodarz D. Gene therapy for killing p53-negative cancer cells: use of replicating versus nonreplicating agents. Hum Gene Ther. 2003 Jan 20; 14(2):153-9. PMID: 12614566.
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    98. Wodarz D. Mathematical models of HIV and the immune system. Novartis Found Symp. 2003; 254:193-207; discussion 207-22, 250-2. PMID: 14712939.
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    99. Belz GT, Wodarz D, Diaz G, Nowak MA, Doherty PC. Compromised influenza virus-specific CD8(+)-T-cell memory in CD4(+)-T-cell-deficient mice. J Virol. 2002 Dec; 76(23):12388-93. PMID: 12414983; PMCID: PMC136883.
    100. Wodarz D, Nowak MA. Mathematical models of HIV pathogenesis and treatment. Bioessays. 2002 Dec; 24(12):1178-87. PMID: 12447982.
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    101. Wodarz D. The persistence of CTL memory. Neth J Med. 2002 Aug; 60(7 Suppl):4-13; discussion 14-6. PMID: 12430586.
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    102. Wodarz D, Christensen JP, Thomsen AR. The importance of lytic and nonlytic immune responses in viral infections. Trends Immunol. 2002 Apr; 23(4):194-200. PMID: 11923114.
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    103. Altes HK, Wodarz D, Jansen VA. The dual role of CD4 T helper cells in the infection dynamics of HIV and their importance for vaccination. J Theor Biol. 2002 Feb 21; 214(4):633-46. PMID: 11851372.
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    104. Wodarz D. Helper-dependent vs. helper-independent CTL responses in HIV infection: implications for drug therapy and resistance. J Theor Biol. 2001 Dec 07; 213(3):447-59. PMID: 11735291.
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    105. Lifson JD, Rossio JL, Piatak M, Parks T, Li L, Kiser R, Coalter V, Fisher B, Flynn BM, Czajak S, Hirsch VM, Reimann KA, Schmitz JE, Ghrayeb J, Bischofberger N, Nowak MA, Desrosiers RC, Wodarz D. Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment. J Virol. 2001 Nov; 75(21):10187-99. PMID: 11581387.
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    106. Wodarz D, Krakauer DC. Genetic instability and the evolution of angiogenic tumor cell lines (review). Oncol Rep. 2001 Nov-Dec; 8(6):1195-201. PMID: 11605033.
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    107. Wodarz D, Jansen VA. The role of T cell help for anti-viral CTL responses. J Theor Biol. 2001 Aug 21; 211(4):419-32. PMID: 11476625.
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    108. Wodarz D, Hall SE, Usuku K, Osame M, Ogg GS, McMichael AJ, Nowak MA, Bangham CR. Cytotoxic T-cell abundance and virus load in human immunodeficiency virus type 1 and human T-cell leukaemia virus type 1. Proc Biol Sci. 2001 Jun 22; 268(1473):1215-21. PMID: 11410146; PMCID: PMC1088729.
    109. Wodarz D. Mechanisms underlying antigen-specific CD8+ T cell homeostasis. Science. 2001 Apr 27; 292(5517):595. PMID: 11326087.
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    110. Wodarz D. Viruses as antitumor weapons: defining conditions for tumor remission. Cancer Res. 2001 Apr 15; 61(8):3501-7. PMID: 11309314.
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    111. Christensen JP, Bartholdy C, Wodarz D, Thomsen AR. Depletion of CD4+ T cells precipitates immunopathology in immunodeficient mice infected with a noncytocidal virus. J Immunol. 2001 Mar 01; 166(5):3384-91. PMID: 11207295.
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    112. Wodarz D. Cytotoxic T-lymphocyte memory, virus clearance and antigenic heterogeneity. Proc Biol Sci. 2001 Feb 22; 268(1465):429-36. PMID: 11270441; PMCID: PMC1088624.
    113. Smith MS, Foresman L, Lopez GJ, Tsay J, Wodarz D, Lifson JD, Page A, Wang C, Li Z, Adany I, Buch S, Bischofberger N, Narayan O. Lasting effects of transient postinoculation tenofovir [9-R-(2-Phosphonomethoxypropyl)adenine] treatment on SHIV(KU2) infection of rhesus macaques. Virology. 2000 Nov 25; 277(2):306-15. PMID: 11080478.
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    114. Bartholdy C, Christensen JP, Wodarz D, Thomsen AR. Persistent virus infection despite chronic cytotoxic T-lymphocyte activation in gamma interferon-deficient mice infected with lymphocytic choriomeningitis virus. J Virol. 2000 Nov; 74(22):10304-11. PMID: 11044074; PMCID: PMC110904.
    115. Wodarz D, Nowak MA. CD8 memory, immunodominance, and antigenic escape. Eur J Immunol. 2000 Sep; 30(9):2704-12. PMID: 11009106.
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    116. Wodarz D, Nowak MA. Correlates of cytotoxic T-lymphocyte-mediated virus control: implications for immunosuppressive infections and their treatment. Philos Trans R Soc Lond B Biol Sci. 2000 Aug 29; 355(1400):1059-70. PMID: 11186307; PMCID: PMC1692817.
    117. Wodarz D, Arnaout RA, Nowak MA, Lifson JD. Transient antiretroviral treatment during acute simian immunodeficiency virus infection facilitates long-term control of the virus. Philos Trans R Soc Lond B Biol Sci. 2000 Aug 29; 355(1400):1021-9. PMID: 11186303; PMCID: PMC1692816.
    118. Thomsen AR, Nansen A, Andreasen SO, Wodarz D, Christensen JP. Host factors influencing viral persistence. Philos Trans R Soc Lond B Biol Sci. 2000 Aug 29; 355(1400):1031-41. PMID: 11186304; PMCID: PMC1692806.
    119. Wodarz D, Krakauer DC. Defining CTL-induced pathology: implications for HIV. Virology. 2000 Aug 15; 274(1):94-104. PMID: 10936092.
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    120. Wodarz D, Nowak MA. HIV therapy: managing resistance. Proc Natl Acad Sci U S A. 2000 Jul 18; 97(15):8193-5. PMID: 10899988; PMCID: PMC34002.
    121. Arnaout RA, Nowak MA, Wodarz D. HIV-1 dynamics revisited: biphasic decay by cytotoxic T lymphocyte killing? Proc Biol Sci. 2000 Jul 07; 267(1450):1347-54. PMID: 10972131; PMCID: PMC1690670.
    122. Barchet W, Oehen S, Klenerman P, Wodarz D, Bocharov G, Lloyd AL, Nowak MA, Hengartner H, Zinkernagel RM, Ehl S. Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo. Eur J Immunol. 2000 May; 30(5):1356-63. PMID: 10820382.
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    123. Wodarz D, Bangham CR. Evolutionary dynamics of HTLV-I. J Mol Evol. 2000 May; 50(5):448-55. PMID: 10824088.
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    124. Wodarz D, May RM, Nowak MA. The role of antigen-independent persistence of memory cytotoxic T lymphocytes. Int Immunol. 2000 Apr; 12(4):467-77. PMID: 10744648.
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    125. Wodarz D, Page KM, Arnaout RA, Thomsen AR, Lifson JD, Nowak MA. A new theory of cytotoxic T-lymphocyte memory: implications for HIV treatment. Philos Trans R Soc Lond B Biol Sci. 2000 Mar 29; 355(1395):329-43. PMID: 10794051; PMCID: PMC1692738.
    126. Lifson JD, Rossio JL, Arnaout R, Li L, Parks TL, Schneider DK, Kiser RF, Coalter VJ, Walsh G, Imming RJ, Fisher B, Flynn BM, Bischofberger N, Piatak M, Hirsch VM, Nowak MA, Wodarz D. Containment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment. J Virol. 2000 Mar; 74(6):2584-93. PMID: 10684272; PMCID: PMC111746.
    127. Wodarz D, Nowak MA. Specific therapy regimes could lead to long-term immunological control of HIV. Proc Natl Acad Sci U S A. 1999 Dec 07; 96(25):14464-9. PMID: 10588728; PMCID: PMC24459.
    128. Wodarz D, Nowak MA. Dynamics of immune escape in HIV infection. Wien Klin Wochenschr. 1999 Jun 04; 111(11):419-27. PMID: 10420492.
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    129. Wodarz D, Nowak MA, Bangham CR. The dynamics of HTLV-I and the CTL response. Immunol Today. 1999 May; 20(5):220-7. PMID: 10322301.
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    130. Bangham CR, Hall SE, Jeffery KJ, Vine AM, Witkover A, Nowak MA, Wodarz D, Usuku K, Osame M. Genetic control and dynamics of the cellular immune response to the human T-cell leukaemia virus, HTLV-I. Philos Trans R Soc Lond B Biol Sci. 1999 Apr 29; 354(1384):691-700. PMID: 10365395; PMCID: PMC1692558.
    131. Wodarz D, Nowak MA. Evolutionary dynamics of HIV-induced subversion of the immune response. Immunol Rev. 1999 Apr; 168:75-89. PMID: 10399066.
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    132. Wodarz D, Lloyd AL, Jansen VA, Nowak MA. Dynamics of macrophage and T cell infection by HIV. J Theor Biol. 1999 Jan 07; 196(1):101-13. PMID: 9892559.
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    133. Wodarz D, Nowak MA. The effect of different immune responses on the evolution of virulent CXCR4-tropic HIV. Proc Biol Sci. 1998 Nov 22; 265(1411):2149-58. PMID: 9872003; PMCID: PMC1689517.
    134. Regoes RR, Wodarz D, Nowak MA. Virus dynamics: the effect of target cell limitation and immune responses on virus evolution. J Theor Biol. 1998 Apr 21; 191(4):451-62. PMID: 9631576.
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    135. Wodarz D, Klenerman P, Nowak MA. Dynamics of cytotoxic T-lymphocyte exhaustion. Proc Biol Sci. 1998 Feb 07; 265(1392):191-203. PMID: 9493406; PMCID: PMC1688878.
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