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Diane K. O'Dowd

Title(s)Vice Provost for Academic Personnel, Academic Affairs
SchoolSchool of Biological Sciences
Address509 Aldrich Hall
Zot 1000
Irvine CA 92697
Phone(949) 824-0663
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    Collapse Research 
    Collapse research activities and funding
    Functional studies of epilepsy mutations in Drosophila and human iPSC-derived neu
    NIH R01NS083009Feb 15, 2014 - Jan 31, 2020
    Role: Principal Investigator
    Role of Nicotine in Regulation of naChRs in Drosophila
    NIH R01DA014690Sep 27, 2001 - Jun 30, 2007
    Role: Principal Investigator
    ION CHANNELS IN DROSOPHILA
    NIH K04NS001854Sep 30, 1995 - Nov 30, 2000
    Role: Principal Investigator
    Central Synaptic Transmission in Drosophila.
    NIH R01NS027501Aug 1, 1989 - Aug 31, 2011
    Role: Principal Investigator
    Central Synaptic Transmission in Drosophila.
    NIH R56NS027501Aug 1, 1989 - Sep 14, 2010
    Role: Principal Investigator
    ION CHANNELS
    NIH R29NS027501Aug 1, 1989 - Jul 31, 1995
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Seizure Phenotype and Underlying Cellular Defects in Drosophila Knock-In Models of DS (R1648C) and GEFS+ (R1648H) SCN1A Epilepsy. eNeuro. 2021 Sep-Oct; 8(5). Roemmich AJ, Vu T, Lukacsovich T, Hawkins C, Schutte SS, O'Dowd DK. PMID: 34475263; PMCID: PMC8454921.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    2. A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy. J Vis Exp. 2021 07 12; (173). Das A, Smith MA, O'Dowd DK. PMID: 34309607.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    3. Interneuron Dysfunction in a New Mouse Model of SCN1A GEFS. eNeuro. 2021 Mar-Apr; 8(2). Das A, Zhu B, Xie Y, Zeng L, Pham AT, Neumann JC, Safrina O, Benavides DR, MacGregor GR, Schutte SS, Hunt RF, O'Dowd DK. PMID: 33658306; PMCID: PMC8174035.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    4. Seven practical strategies to add active learning to a science lecture. Neurosci Lett. 2021 01 19; 743:135317. Williams AE, O'Dowd DK. PMID: 33310061.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    5. Comparisons of dual isogenic human iPSC pairs identify functional alterations directly caused by an epilepsy associated SCN1A mutation. Neurobiol Dis. 2020 02; 134:104627. Xie Y, Ng NN, Safrina OS, Ramos CM, Ess KC, Schwartz PH, Smith MA, O'Dowd DK. PMID: 31786370.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    6. Reproducible and efficient generation of functionally active neurons from human hiPSCs for preclinical disease modeling. Stem Cell Res. 2018 01; 26:84-94. Xie Y, Schutte RJ, Ng NN, Ess KC, Schwartz PH, O'Dowd DK. PMID: 29272856; PMCID: PMC5899925.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    7. Astrocyte-enriched feeder layers from cryopreserved cells support differentiation of spontaneously active networks of human iPSC-derived neurons. J Neurosci Methods. 2018 01 15; 294:91-101. Schutte RJ, Xie Y, Ng NN, Figueroa P, Pham AT, O'Dowd DK. PMID: 28746822; PMCID: PMC5776056.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    8. Model systems for studying cellular mechanisms of SCN1A-related epilepsy. J Neurophysiol. 2016 Apr; 115(4):1755-66. Schutte SS, Schutte RJ, Barragan EV, O'Dowd DK. PMID: 26843603; PMCID: PMC4819066.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    9. Knock-in model of Dravet syndrome reveals a constitutive and conditional reduction in sodium current. J Neurophysiol. 2014 Aug 15; 112(4):903-12. Schutte RJ, Schutte SS, Algara J, Barragan EV, Gilligan J, Staber C, Savva YA, Smith MA, Reenan R, O'Dowd DK. PMID: 24805083; PMCID: PMC4122742.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    10. Garage demos: using physical models to illustrate dynamic aspects of microscopic biological processes. CBE Life Sci Educ. 2009; 8(2):118-22. O'Dowd DK, Aguilar-Roca N. PMID: 19487500; PMCID: PMC2689147.
      View in: PubMed   Mentions: 6     Fields:    
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