Diane Jean Nugent

Title(s)Health Sciences Professor, Pediatrics
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 509-8459
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    Collapse Research 
    Collapse Research Activities and Funding
    Preventing Bleeding Disorder Complications thru Hemophilia Tx Ctrs in Region IX
    NIH U01DD000204Sep 30, 2006 - Sep 29, 2011
    Role: Principal Investigator
    PATHOGENESIS OF AUTOIMMUNE THROMBOCYTOPENIA
    NIH R01HL061846Sep 30, 1998 - Feb 28, 2004
    Role: Principal Investigator
    PLATELET AUTOANTIGENS
    NIH K08HL001649Feb 1, 1986 - Jan 31, 1991
    Role: Principal Investigator
    HUMAN MONOCLONAL ANTIBODIES
    NIH R01DK033345Jan 1, 1984 - Jun 30, 1995
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. PFA-100 System: A New Method for Assessment of Platelet Dysfunction. Semin Thromb Hemost. 2023 Dec 13. Mammen EF, Comp PC, Gosselin R, Greenberg C, Hoots WK, Kessler CM, Larkin EC, Liles D, Nugent DJ. PMID: 38092024.
      View in: PubMed   Mentions:    Fields:    
    2. Paediatric-onset Evans syndrome: Breaking away from refractory immune thrombocytopenia. Br J Haematol. 2023 10; 203(1):28-35. Aladjidi N, Pincez T, Rieux-Laucat F, Nugent D. PMID: 37735545.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities for ultra-rare inherited bleeding disorders. Expert Rev Hematol. 2023 03; 16(sup1):55-70. Nugent D, Acharya SS, Baumann KJ, Bedrosian C, Bialas R, Brown K, Corzo D, Haidar A, Hayward CPM, Marks P, Menegatti M, Miller ME, Nammacher K, Palla R, Peltier S, Pruthi RK, Recht M, Sørensen B, Tarantino M, Wolberg AS, Shapiro AD. PMID: 36920862; PMCID: PMC10020868.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    4. Use of COVID-19 Convalescent Plasma for Treatment of Symptomatic SARS-CoV-2 Infection at a Children's Hospital: A Contribution to a Still Inadequate Body of Evidence. Children (Basel). 2023 Feb 10; 10(2). Arrieta A, Galvis AE, Osborne S, Morphew T, Imfeld K, Enriquez C, Hoang J, Swearingen M, Nieves DJ, Ashouri N, Singh J, Nugent D. PMID: 36832478; PMCID: PMC9955755.
      View in: PubMed   Mentions: 1  
    5. The American Society of Pediatric Hematology Oncology workforce, productivity, and fellowship assessment: Current state of the workforce. Pediatr Blood Cancer. 2023 05; 70(5):e30221. Hastings C, Borinstein SC, Bergsagel DJ, Hagstrom JN, Hooker R, Nugent DJ, Hudspeth M, American Society of Pediatric Hematology Oncology Workforce Publication Workgroup. PMID: 36722007.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Unaffected Li-Fraumeni Syndrome Carrier Parent Demonstrates Allele-Specific mRNA Stabilization of Wild-Type TP53 Compared to Affected Offspring. Genes (Basel). 2022 Dec 07; 13(12). Buzby JS, Williams SA, Nugent DJ. PMID: 36553570.
      View in: PubMed   Mentions:    Fields:    
    7. Barriers to hydroxyurea use from the perspectives of providers, individuals with sickle cell disease, and families: Report from a U.S. regional collaborative. Front Genet. 2022; 13:921432. Treadwell MJ, Du L, Bhasin N, Marsh AM, Wun T, Bender MA, Wong TE, Crook N, Chung JH, Norman S, Camilo N, Cavazos J, Nugent D. PMID: 36092883; PMCID: PMC9461276.
      View in: PubMed   Mentions: 3  
    8. The Hemophilia Joint Health Score version 2.1 Validation in Adult Patients Study: A multicenter international study. Res Pract Thromb Haemost. 2022 Feb; 6(2):e12690. St-Louis J, Abad A, Funk S, Tilak M, Classey S, Zourikian N, McLaughlin P, Lobet S, Hernandez G, Akins S, Wells AJ, Manco-Johnson M, John J, Austin S, Chowdhary P, Hermans C, Nugent D, Bakeer N, Mangles S, Hilliard P, Blanchette VS, Feldman BM. PMID: 35356667; PMCID: PMC8956786.
      View in: PubMed   Mentions: 13  
    9. Safety and effectiveness of recombinant factor XIII-A2 in congenital factor XIII deficiency: Real-world evidence. Res Pract Thromb Haemost. 2022 Feb; 6(2):e12628. Poulsen LH, Kerlin BA, Castaman G, Molinari AC, Menegatti M, Nugent D, Dey S, Garly ML, Carcao M. PMID: 35243202; PMCID: PMC8882239.
      View in: PubMed   Mentions: 1  
    10. Integrated Hemophilia Patient Care via a National Network of Care Centers in the United States: A Model for Rare Coagulation Disorders. J Blood Med. 2021; 12:897-911. Valentino LA, Baker JR, Butler R, Escobar M, Frick N, Karp S, Koulianos K, Lattimore S, Nugent D, Pugliese JN, Recht M, Reding MT, Rice M, Thibodeaux CB, Skinner M. PMID: 34707421; PMCID: PMC8544265.
      View in: PubMed   Mentions: 11  
    11. Rapid antibody testing for SARS-CoV-2 vaccine response in pediatric healthcare workers. Int J Infect Dis. 2021 Dec; 113:1-6. Heyming TW, Nugent D, Tongol A, Knudsen-Robbins C, Hoang J, Schomberg J, Bacon K, Lara B, Sanger T. PMID: 34601142; PMCID: PMC8482557.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Patient preferences and priorities for haemophilia gene therapy in the US: A discrete choice experiment. Haemophilia. 2021 Sep; 27(5):769-782. Witkop M, Morgan G, O'Hara J, Recht M, Buckner TW, Nugent D, Curtis R, O'Mahony B, Skinner MW, Mulhern B, Cawson M, Ali TM, Sawyer EK, Li N. PMID: 34310811; PMCID: PMC9290457.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    13. Safety and Antibody Kinetics of COVID-19 Convalescent Plasma for the Treatment of Moderate to Severe Cases of SARS-CoV-2 Infection in Pediatric Patients. Pediatr Infect Dis J. 2021 07 01; 40(7):606-611. Arrieta A, Galvis AE, Morphew T, Ehwerhemuepha L, Osborne S, Enriquez C, Imfeld K, Hoang J, Nieves D, Ashouri N, Singh J, Nugent D. PMID: 33967228.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. Misdiagnosed thrombocytopenia in children and adolescents: analysis of the Pediatric and Adult Registry on Chronic ITP. Blood Adv. 2021 03 23; 5(6):1617-1626. Schifferli A, Heiri A, Imbach P, Holzhauer S, Seidel MG, Nugent D, Michel M, Kühne T. PMID: 33710335; PMCID: PMC7993109.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Patient-relevant health outcomes for hemophilia care: Development of an international standard outcomes set. Res Pract Thromb Haemost. 2021 May; 5(4):e12488. van Balen EC, O'Mahony B, Cnossen MH, Dolan G, Blanchette VS, Fischer K, Gue D, O'Hara J, Iorio A, Jackson S, Konkle BA, Nugent DJ, Coffin D, Skinner MW, Smit C, Srivastava A, van Eenennaam F, van der Bom JG, Gouw SC. PMID: 34027286; PMCID: PMC8117824.
      View in: PubMed   Mentions: 14  
    16. Evidence of a disability paradox in patient-reported outcomes in haemophilia. Haemophilia. 2021 Mar; 27(2):245-252. O'Hara J, Martin AP, Nugent D, Witkop M, Buckner TW, Skinner MW, O'Mahony B, Mulhern B, Morgan G, Li N, Sawyer EK. PMID: 33595148; PMCID: PMC8048516.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    17. When Screening for Severe Combined Immunodeficiency (SCID) with T Cell Receptor Excision Circles Is Not SCID: a Case-Based Review. J Clin Immunol. 2021 02; 41(2):294-302. Buchbinder D, Walter JE, Butte MJ, Chan WY, Chitty Lopez M, Dimitriades VR, Dorsey MJ, Nugent DJ, Puck JM, Singh J, Collins CA. PMID: 33411155; PMCID: PMC8179373.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsPHPublic Health
    18. The Need for Comprehensive Care for Persons with Chronic Immune Thrombocytopenic Purpura. J Blood Med. 2020; 11:457-463. Ansteatt KT, Unzicker CJ, Hurn ML, Olaiya OO, Nugent DJ, Tarantino MD. PMID: 33364868; PMCID: PMC7751596.
      View in: PubMed   Mentions: 1  
    19. Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome. Blood. 2020 10 22; 136(17):1956-1967. Sims MC, Mayer L, Collins JH, Bariana TK, Megy K, Lavenu-Bombled C, Seyres D, Kollipara L, Burden FS, Greene D, Lee D, Rodriguez-Romera A, Alessi MC, Astle WJ, Bahou WF, Bury L, Chalmers E, Da Silva R, De Candia E, Deevi SVV, Farrow S, Gomez K, Grassi L, Greinacher A, Gresele P, Hart D, Hurtaud MF, Kelly AM, Kerr R, Le Quellec S, Leblanc T, Leinøe EB, Mapeta R, McKinney H, Michelson AD, Morais S, Nugent D, Papadia S, Park SJ, Pasi J, Podda GM, Poon MC, Reed R, Sekhar M, Shalev H, Sivapalaratnam S, Steinberg-Shemer O, Stephens JC, Tait RC, Turro E, Wu JKM, Zieger B, NIHR BioResource, Kuijpers TW, Whetton AD, Sickmann A, Freson K, Downes K, Erber WN, Frontini M, Nurden P, Ouwehand WH, Favier R, Guerrero JA. PMID: 32693407; PMCID: PMC7582559.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    20. High-grade heart block requiring transvenous pacing associated with multisystem inflammatory syndrome in children during the COVID-19 pandemic. HeartRhythm Case Rep. 2020 Nov; 6(11):811-814. Domico M, McCanta AC, Hunt JL, Ashouri N, Nugent D, Kelly RB. PMID: 32864334; PMCID: PMC7446646.
      View in: PubMed   Mentions: 9  
    21. Achieving the unimaginable: Health equity in haemophilia. Haemophilia. 2020 Jan; 26(1):17-24. Skinner MW, Nugent D, Wilton P, O'Mahony B, Dolan G, O'Hara J, Berntorp E. PMID: 31724316; PMCID: PMC7891319.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    22. Parent proxy assessment of sibling quality of life following pediatric hematopoietic cell transplantation. Health Qual Life Outcomes. 2019 Oct 29; 17(1):162. Buchbinder D, Patel SK, Casillas JN, Nugent DJ, Neudorf S, Sender LS, Torno L, Huszti H, Zeltzer LK, Parsons SK. PMID: 31665035; PMCID: PMC6819636.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. Hemophilia - Impact of Recent Advances on Management. Indian J Pediatr. 2020 02; 87(2):134-140. Puthenveetil G, Nugent D. PMID: 31529382.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Executive summary of the NHLBI State of the Science (SOS) Workshop: Overview and next steps in generating a national blueprint for future research on factor VIII inhibitors. Haemophilia. 2019 Jul; 25(4):610-615. Pipe SW, Sabatino DE, Nugent DJ, Hooper WC, Soucie JM, Keith Hoots W, DiMichele DM. PMID: 31329363.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    25. Origins and organization of the NHLBI State of the Science Workshop: Generating a national blueprint for future research on factor VIII inhibitors. Haemophilia. 2019 Jul; 25(4):575-580. Sabatino DE, Pipe SW, Nugent DJ, Soucie JM, Hooper WC, Hoots WK, DiMichele DM. PMID: 31329369; PMCID: PMC7235928.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Promising biomarkers for the prediction of catheter-related venous thromboembolism in hospitalized children: An exploratory study. Pediatr Blood Cancer. 2019 10; 66(10):e27870. Nossair F, Mahajerin A, Hoang J, Diaz D, Nugent D. PMID: 31222954.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Rubella Virus-Associated Cutaneous Granulomatous Disease: a Unique Complication in Immune-Deficient Patients, Not Limited to DNA Repair Disorders. J Clin Immunol. 2019 01; 39(1):81-89. Buchbinder D, Hauck F, Albert MH, Rack A, Bakhtiar S, Shcherbina A, Deripapa E, Sullivan KE, Perelygina L, Eloit M, Neven B, Pérot P, Moshous D, Suarez F, Bodemer C, Bonilla FA, Vaz LE, Krol AL, Klein C, Seppanen M, Nugent DJ, Singh J, Ochs HD. PMID: 30607663; PMCID: PMC7739844.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    28. Evaluation of bleeding disorders in patients with Noonan syndrome: a systematic review. J Blood Med. 2018; 9:185-192. Nugent DJ, Romano AA, Sabharwal S, Cooper DL. PMID: 30464668; PMCID: PMC6208935.
      View in: PubMed   Mentions: 17  
    29. Value of prophylaxis vs on-demand treatment: Application of a value framework in hemophilia. Haemophilia. 2018 Sep; 24(5):755-765. Nugent D, O'Mahony B, Dolan G, International Haemophilia Access Strategy Council. PMID: 30088692.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    30. Clinical Challenges: Identification of Patients With Novel Primary Immunodeficiency Syndromes. J Pediatr Hematol Oncol. 2018 07; 40(5):e319-e322. Buchbinder D, Seppanen M, Rao VK, Uzel G, Nugent D. PMID: 29200144; PMCID: PMC5984070.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    31. Patient-centred value framework for haemophilia. Haemophilia. 2018 Nov; 24(6):873-879. O'Mahony B, Dolan G, Nugent D, Goodman C, International Haemophilia Access Strategy Council. PMID: 29626368.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    32. Recombinant FXIII (rFXIII-A2) Prophylaxis Prevents Bleeding and Allows for Surgery in Patients with Congenital FXIII A-Subunit Deficiency. Thromb Haemost. 2018 03; 118(3):451-460. Carcao M, Altisent C, Castaman G, Fukutake K, Kerlin BA, Kessler C, Lassila R, Nugent D, Oldenburg J, Garly ML, Rosholm A, Inbal A. PMID: 29448295; PMCID: PMC6260112.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    33. Estimating the potential cost of a high dose immune tolerance induction (ITI) therapy relative to the cost of a combined therapy of a low dose ITI therapy with bypassing agent prophylaxis. Haemophilia. 2017 Sep; 23(5):e394-e402. Kenet G, Oladapo A, Epstein JD, Thompson C, Novack A, Nugent DJ. PMID: 28641362.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    34. Spotlight on romiplostim in the treatment of children with chronic immune thrombocytopenia: design, development, and potential place in therapy. Drug Des Devel Ther. 2017; 11:1055-1063. Buchbinder D, Nugent D, Hsieh L. PMID: 28408804; PMCID: PMC5384698.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. Allele-specific wild-type TP53 expression in the unaffected carrier parent of children with Li-Fraumeni syndrome. Cancer Genet. 2017 02; 211:9-17. Buzby JS, Williams SA, Schaffer L, Head SR, Nugent DJ. PMID: 28279309; PMCID: PMC5347445.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Platelet genomics: the role of platelet size and number in health and disease. Platelets. 2017 Jan; 28(1):27-33. Nugent D, Kunicki T. PMID: 28032522.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    37. Complications of haemophilia in babies (first two years of life): a report from the Centers for Disease Control and Prevention Universal Data Collection System. Haemophilia. 2017 Mar; 23(2):207-214. Kulkarni R, Presley RJ, Lusher JM, Shapiro AD, Gill JC, Manco-Johnson M, Koerper MA, Abshire TC, DiMichele D, Hoots WK, Mathew P, Nugent DJ, Geraghty S, Evatt BL, Soucie JM. PMID: 27813214; PMCID: PMC5354941.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    38. Developing the First Recombinant Factor XIII for Congenital Factor XIII Deficiency: Clinical Challenges and Successes. Semin Thromb Hemost. 2017 Feb; 43(1):59-68. Carcao M, Fukutake K, Inbal A, Kerlin B, Lassila R, Oldenburg J, Garly ML, Nugent D. PMID: 27556350.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    39. Unrelated Hematopoietic Cell Transplantation in a Patient with Combined Immunodeficiency with Granulomatous Disease and Autoimmunity Secondary to RAG Deficiency. J Clin Immunol. 2016 10; 36(7):725-32. John T, Walter JE, Schuetz C, Chen K, Abraham RS, Bonfim C, Boyce TG, Joshi AY, Kang E, Carvalho BT, Mahajerin A, Nugent D, Puthenveetil G, Soni A, Su H, Cowan MJ, Notarangelo L, Buchbinder D. PMID: 27539235; PMCID: PMC5286911.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    40. Rare coagulation disorders: fibrinogen, factor VII and factor XIII. Haemophilia. 2016 Jul; 22 Suppl 5:61-5. de Moerloose P, Schved JF, Nugent D. PMID: 27405678.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    41. Viruses, anti-viral therapy, and viral vaccines in children with immune thrombocytopenia. Semin Hematol. 2016 04; 53 Suppl 1:S70-2. Elalfy MS, Nugent D. PMID: 27312173.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    42. Associations of quality of life, pain, and self-reported arthritis with age, employment, bleed rate, and utilization of hemophilia treatment center and health care provider services: results in adults with hemophilia in the HERO study. Patient Prefer Adherence. 2015; 9:1549-60. Forsyth AL, Witkop M, Lambing A, Garrido C, Dunn S, Cooper DL, Nugent DJ. PMID: 26604708; PMCID: PMC4631419.
      View in: PubMed   Mentions: 32  
    43. Successful treatment of secondary graft failure following unrelated cord blood transplant with hematopoietic growth factors in a pediatric patient with Fanconi anemia. Pediatr Transplant. 2015 Nov; 19(7):E181-4. Buchbinder D, Hsieh L, Mahajerin A, Puthenveetil G, Soni A, Nugent D. PMID: 26228438.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. Changes in bleeding patterns in von Willebrand disease after institution of long-term replacement therapy: results from the von Willebrand Disease Prophylaxis Network. Blood Coagul Fibrinolysis. 2015 Jun; 26(4):383-8. Holm E, Abshire TC, Bowen J, Álvarez MT, Bolton-Maggs P, Carcao M, Federici AB, Gill JC, Halimeh S, Kempton C, Key NS, Kouides P, Lail A, Landorph A, Leebeek F, Makris M, Mannucci P, Mauser-Bunschoten EP, Nugent D, Valentino LA, Winikoff R, Berntorp E. PMID: 25688461.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    45. Expanding the Mutation Spectrum Affecting αIIbβ3 Integrin in Glanzmann Thrombasthenia: Screening of the ITGA2B and ITGB3 Genes in a Large International Cohort. Hum Mutat. 2015 May; 36(5):548-61. Nurden AT, Pillois X, Fiore M, Alessi MC, Bonduel M, Dreyfus M, Goudemand J, Gruel Y, Benabdallah-Guerida S, Latger-Cannard V, Négrier C, Nugent D, Oiron RD, Rand ML, Sié P, Trossaert M, Alberio L, Martins N, Sirvain-Trukniewicz P, Couloux A, Canault M, Fronthroth JP, Fretigny M, Nurden P, Heilig R, Vinciguerra C. PMID: 25728920.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    46. Mild B-cell lymphocytosis in patients with a CARD11 C49Y mutation. J Allergy Clin Immunol. 2015 Sep; 136(3):819-821.e1. Buchbinder D, Stinson JR, Nugent DJ, Heurtier L, Suarez F, Sukumar G, Dalgard CL, Masson C, Parisot M, Zhang Y, Matthews HF, Su HC, Durandy A, Fischer A, Kracker S, Snow AL. PMID: 25930198; PMCID: PMC4562870.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    47. Pharmacokinetic characterization of recombinant factor XIII (FXIII)-A2 across age groups in patients with FXIII A-subunit congenital deficiency. Haemophilia. 2015 May; 21(3):380-385. Brand-Staufer B, Carcao M, Kerlin BA, Will A, Williams M, Tornøe CW, Sandberg Lundblad M, Nugent D. PMID: 25643920.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    48. Identification of patients with RAG mutations previously diagnosed with common variable immunodeficiency disorders. J Clin Immunol. 2015 Feb; 35(2):119-24. Buchbinder D, Baker R, Lee YN, Ravell J, Zhang Y, McElwee J, Nugent D, Coonrod EM, Durtschi JD, Augustine NH, Voelkerding KV, Csomos K, Rosen L, Browne S, Walter JE, Notarangelo LD, Hill HR, Kumánovics A. PMID: 25516070; PMCID: PMC4479182.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    49. Pharmacokinetics and safety of plasma-derived factor XIII concentrate (human) in patients with congenital factor XIII deficiency. Haemophilia. 2015 Jan; 21(1):95-101. Nugent DJ, Ashley C, García-Talavera J, Lo LC, Mehdi AS, Mangione A. PMID: 25458735.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    50. Efficacy and safety of prophylactic treatment with plasma-derived factor XIII concentrate (human) in patients with congenital factor XIII deficiency. Haemophilia. 2015 Jan; 21(1):102-8. Ashley C, Chang E, Davis J, Mangione A, Frame V, Nugent DJ. PMID: 25377187.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    51. Haemophilia Experiences, Results and Opportunities (HERO) study: treatment-related characteristics of the population. Haemophilia. 2015 Jan; 21(1):e26-38. Nugent D, Kalnins W, Querol F, Gregory M, Pilgaard T, Cooper DL, Iorio A. PMID: 25377442.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    52. Pharmacokinetics of recombinant factor XIII at steady state in patients with congenital factor XIII A-subunit deficiency. J Thromb Haemost. 2014 Dec; 12(12):2038-43. Kerlin B, Brand B, Inbal A, Halimeh S, Nugent D, Lundblad M, Tehranchi R. PMID: 25263390.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    53. Successful treatment of post-transplant thrombocytopenia with romiplostim in a pediatric patient with X-linked chronic granulomatous disease. Pediatr Transplant. 2014 Nov; 18(7):E252-4. Buchbinder D, Hsieh L, Krance R, Nugent DJ. PMID: 25118016.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    54. Use of Factor XIII (FXIII) concentrate in patients with congenital FXIII deficiency undergoing surgical procedures. Transfusion. 2015 Jan; 55(1):45-50. Janbain M, Nugent DJ, Powell JS, St-Louis J, Frame VB, Leissinger CA. PMID: 25070582.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    55. Diagnosis of suspected inherited platelet function disorders: results of a worldwide survey. J Thromb Haemost. 2014 Sep; 12(9):1562-9. Gresele P, Harrison P, Bury L, Falcinelli E, Gachet C, Hayward CP, Kenny D, Mezzano D, Mumford AD, Nugent D, Nurden AT, Orsini S, Cattaneo M. PMID: 24976115.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    56. Thrombopoietic agents for the treatment of persistent and chronic immune thrombocytopenia in children. J Pediatr. 2014 Sep; 165(3):600-5.e4. Ramaswamy K, Hsieh L, Leven E, Thompson MV, Nugent D, Bussel JB. PMID: 24857517.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    57. Haemophilia Experiences, Results and Opportunities (HERO) Study: influence of haemophilia on interpersonal relationships as reported by adults with haemophilia and parents of children with haemophilia. Haemophilia. 2014 Jul; 20(4):e287-95. Cassis FR, Buzzi A, Forsyth A, Gregory M, Nugent D, Garrido C, Pilgaard T, Cooper DL, Iorio A. PMID: 24800872.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    58. Wiskott-Aldrich syndrome: diagnosis, current management, and emerging treatments. Appl Clin Genet. 2014; 7:55-66. Buchbinder D, Nugent DJ, Fillipovich AH. PMID: 24817816; PMCID: PMC4012343.
      View in: PubMed   Mentions: 37  
    59. Effects of hematopoietic stem cell transplantation on acyl-CoA oxidase deficiency: a sibling comparison study. J Inherit Metab Dis. 2014 Sep; 37(5):791-9. Wang RY, Monuki ES, Powers J, Schwartz PH, Watkins PA, Shi Y, Moser A, Shrier DA, Waterham HR, Nugent DJ, Abdenur JE. PMID: 24619150; PMCID: PMC4332804.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    60. Tissue factor inflammatory response regulated by promoter genotype and p38 MAPK in neonatal vs. adult microvascular endothelial cells. Inflamm Res. 2014 Apr; 63(4):299-308. Buzby JS, Williams SA, Imfeld KL, Kunicki TJ, Nugent DJ. PMID: 24385191; PMCID: PMC3954954.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    61. Newborn screening for severe combined immunodeficiency: an opportunity for intervention. J Perinatol. 2013 Aug; 33(8):657-8. Buchbinder D, Puthenveetil G, Soni A, Hsieh L, Nugent D, Church JA. PMID: 23897312.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    62. Haemophilia Experiences, Results and Opportunities (HERO) Study: survey methodology and population demographics. Haemophilia. 2014 Jan; 20(1):44-51. Forsyth AL, Gregory M, Nugent D, Garrido C, Pilgaard T, Cooper DL, Iorio A. PMID: 23902228.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    63. Recommendations for the Standardization of Light Transmission Aggregometry: A Consensus of the Working Party from the Platelet Physiology Subcommittee of SSC/ISTH. J Thromb Haemost. 2013 Apr 10. Cattaneo M, Cerletti C, Harrison P, Hayward CP, Kenny D, Nugent D, Nurden P, Rao AK, Schmaier AH, Watson SP, Lussana F, Pugliano MT, Michelson AD. PMID: 23574625.
      View in: PubMed   Mentions: 124     Fields:    
    64. Successful autologous cord blood transplantation in a child with acquired severe aplastic anemia. Pediatr Transplant. 2013 May; 17(3):E104-7. Buchbinder D, Hsieh L, Puthenveetil G, Soni A, Stites J, Huynh V, Kirov I, Neudorf S, Rubin E, Sender L, Torno L, Margolis D, Childs R, Moore T, Nugent D. PMID: 23464883; PMCID: PMC4174564.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    65. Conditional knockout of integrin α2β1 in murine megakaryocytes leads to reduced mean platelet volume. PLoS One. 2013; 8(1):e55094. Habart D, Cheli Y, Nugent DJ, Ruggeri ZM, Kunicki TJ. PMID: 23359821; PMCID: PMC3554675.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    66. Corifact™/Fibrogammin® P in the prophylactic treatment of hereditary factor XIII deficiency: results of a prospective, multicenter, open-label study. Thromb Res. 2012 Dec; 130 Suppl 2:S12-4. Nugent D. PMID: 23439001.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    67. Genetic variants that affect platelet function. Curr Opin Hematol. 2012 Sep; 19(5):371-9. Kunicki TJ, Williams SA, Nugent DJ. PMID: 22872156.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    68. Rare factor deficiencies. Curr Opin Hematol. 2012 Sep; 19(5):380-4. Hsieh L, Nugent D. PMID: 22872158.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    69. Successful cord blood transplantation in a patient with malignant infantile osteopetrosis and hemophilia. Pediatr Transplant. 2013 Feb; 17(1):E20-4. Buchbinder D, Steward CG, Puthenveetil G, Nugent D, Hsieh L, Kirov I, Neudorf S, Soni A. PMID: 22913475.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    70. Late effects in hematopoietic cell transplant recipients with acquired severe aplastic anemia: a report from the late effects working committee of the center for international blood and marrow transplant research. Biol Blood Marrow Transplant. 2012 Dec; 18(12):1776-84. Buchbinder D, Nugent DJ, Brazauskas R, Wang Z, Aljurf MD, Cairo MS, Chow R, Duncan C, Eldjerou LK, Gupta V, Hale GA, Halter J, Hayes-Lattin BM, Hsu JW, Jacobsohn DA, Kamble RT, Kasow KA, Lazarus HM, Mehta P, Myers KC, Parsons SK, Passweg JR, Pidala J, Reddy V, Sales-Bonfim CM, Savani BN, Seber A, Sorror ML, Steinberg A, Wood WA, Wall DA, Winiarski JH, Yu LC, Majhail NS. PMID: 22863842; PMCID: PMC3496823.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    71. X-linked hyper IgM syndrome: a novel sequence variant associated with an atypical mild phenotype. J Pediatr Hematol Oncol. 2012 Jul; 34(5):e212-4. Buchbinder D, Park S, Nugent D. PMID: 22322937.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    72. Recombinant factor XIII: a safe and novel treatment for congenital factor XIII deficiency. Blood. 2012 May 31; 119(22):5111-7. Inbal A, Oldenburg J, Carcao M, Rosholm A, Tehranchi R, Nugent D. PMID: 22451421.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    73. A patient with familial bone marrow failure and an inversion of chromosome 8. J Pediatr Hematol Oncol. 2011 Dec; 33(8):626-7. Buchbinder DK, Zadeh T, Nugent D. PMID: 22042281.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    74. Platelet adhesion to decorin but not collagen I correlates with the integrin α2 dimorphism E534K, the basis of the human platelet alloantigen (HPA)-5 system. Haematologica. 2012 May; 97(5):692-5. Kunicki TJ, Williams SA, Diaz D, Farndale RW, Nugent DJ. PMID: 22133774; PMCID: PMC3342970.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    75. Mean platelet volume and integrin alleles correlate with levels of integrins α(IIb)β(3) and α(2)β(1) in acute coronary syndrome patients and normal subjects. Arterioscler Thromb Vasc Biol. 2012 Jan; 32(1):147-52. Kunicki TJ, Williams SA, Nugent DJ, Yeager M. PMID: 22015659.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    76. Inflammatory polyps following successful HLA-matched cord blood transplantation in a patient with X-linked lymphoproliferative syndrome. Pediatr Transplant. 2012 Aug; 16(5):E188-91. Buchbinder D, Younes B, Sassoon A, Soni A, Hsieh L, Puthenveetil G, Stites J, Ness-Jorden T, Neudorf S, Nugent D. PMID: 21736679.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    77. Surveillance of female patients with inherited bleeding disorders in United States Haemophilia Treatment Centres. Haemophilia. 2011 Jul; 17 Suppl 1:6-13. Byams VR, Kouides PA, Kulkarni R, Baker JR, Brown DL, Gill JC, Grant AM, James AH, Konkle BA, Maahs J, Dumas MM, McAlister S, Nance D, Nugent D, Philipp CS, Soucie JM, Stang E, Haemophilia Treatment Centres Network Investigators. PMID: 21692922; PMCID: PMC4467796.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansPHPublic Health
    78. Monozygotic twin pair showing discordant phenotype for X-linked thrombocytopenia and Wiskott-Aldrich syndrome: a role for epigenetics? J Clin Immunol. 2011 Oct; 31(5):773-7. Buchbinder D, Nadeau K, Nugent D. PMID: 21710275.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    79. Response to steroids predicts response to rituximab in pediatric chronic immune thrombocytopenia. Pediatr Blood Cancer. 2012 Feb; 58(2):221-5. Grace RF, Bennett CM, Ritchey AK, Jeng M, Thornburg CD, Lambert MP, Neier M, Recht M, Kumar M, Blanchette V, Klaassen RJ, Buchanan GR, Kurth MH, Nugent DJ, Thompson AA, Stine K, Kalish LA, Neufeld EJ. PMID: 21674758; PMCID: PMC3863944.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    80. Screening for von Willebrand disease in children: a case-control study. J Thromb Haemost. 2011 May; 9(5):1086-9. Bujnicki HC, Sidonio RF, Kempton C, Kouides PA, Kulkarni R, Nugent DJ, Yee DL, Moore CG, Ragni MV. PMID: 21410642.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    81. A randomized, double-blind study of romiplostim to determine its safety and efficacy in children with immune thrombocytopenia. Blood. 2011 Jul 07; 118(1):28-36. Bussel JB, Buchanan GR, Nugent DJ, Gnarra DJ, Bomgaars LR, Blanchette VS, Wang YM, Nie K, Jun S. PMID: 21502541.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    82. Standardization of thromboelastography: a report from the TEG-ROTEM working group. Haemophilia. 2011 May; 17(3):532-7. Chitlur M, Sorensen B, Rivard GE, Young G, Ingerslev J, Othman M, Nugent D, Kenet G, Escobar M, Lusher J. PMID: 21323795.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    83. FondaKIDS: a prospective pharmacokinetic and safety study of fondaparinux in children between 1 and 18 years of age. Pediatr Blood Cancer. 2011 Dec 01; 57(6):1049-54. Young G, Yee DL, O'Brien SH, Khanna R, Barbour A, Nugent DJ. PMID: 21319285.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    84. von Willebrand factor: what is its role in the immune response in haemophilia? Haemophilia. 2011 Jan; 17(1):e235-8. Kaveri S, Mannucci PM, Kurth MH, Ewing N, Kessler CM, Nugent DJ, Gomperts ED. PMID: 20546026.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    85. Unrelated hematopoietic stem cell transplantation in a patient with congenital dyserythropoietic anemia and iron overload. Pediatr Transplant. 2012 May; 16(3):E69-73. Buchbinder D, Nugent D, Vu D, Soni A, Stites J, Hsieh L, Puthenveetil G. PMID: 21108711.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    86. Living Profiles: design of a health media platform for teens with special healthcare needs. J Biomed Inform. 2010 Oct; 43(5 Suppl):S9-S12. Chira P, Nugent L, Miller K, Park T, Donahue S, Soni A, Nugent D, Sandborg C. PMID: 20937487.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    87. The genetics of normal platelet reactivity. Blood. 2010 Oct 14; 116(15):2627-34. Kunicki TJ, Nugent DJ. PMID: 20610812; PMCID: PMC2974578.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    88. Consensus Paper-ICIS Expert Meeting Basel 2009 treatment milestones in immune thrombocytopenia. Ann Hematol. 2010 Jul; 89 Suppl 1:5-10. Tamary H, Roganovic J, Chitlur M, Nugent DJ. PMID: 20358200; PMCID: PMC2900598.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    89. Enhanced binding of poly(ADP-ribose)polymerase-1 and Ku80/70 to the ITGA2 promoter via an extended cytosine-adenosine repeat. PLoS One. 2010 Jan 15; 5(1):e8743. Cheli Y, Williams SA, Ballotti R, Nugent DJ, Kunicki TJ. PMID: 20090957; PMCID: PMC2806922.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    90. Comparison of kaolin and tissue factor activated thromboelastography in haemophilia. Haemophilia. 2010 May; 16(3):518-24. Young G, Zhang R, Miller R, Yassin D, Nugent DJ. PMID: 20028419.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    91. Prophylactic therapy with Fibrogammin P is associated with a decreased incidence of bleeding episodes: a retrospective study. Haemophilia. 2010 Mar; 16(2):316-21. Lusher J, Pipe SW, Alexander S, Nugent D. PMID: 20017752.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    92. Genetics of platelet reactivity in normal, healthy individuals. J Thromb Haemost. 2009 Dec; 7(12):2116-22. Kunicki TJ, Williams SA, Salomon DR, Harrison P, Crisler P, Nakagawa P, Mondala TS, Head SR, Nugent DJ. PMID: 19740098.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    93. Off-label use of rFVIIa in children with excessive bleeding: a consecutive study of 153 off-label uses in 139 children. Pediatr Blood Cancer. 2009 Aug; 53(2):179-83. Young G, Wicklund B, Neff P, Johnson C, Nugent DJ. PMID: 19415741.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    94. Sites of initial bleeding episodes, mode of delivery and age of diagnosis in babies with haemophilia diagnosed before the age of 2 years: a report from The Centers for Disease Control and Prevention's (CDC) Universal Data Collection (UDC) project. Haemophilia. 2009 Nov; 15(6):1281-90. Kulkarni R, Soucie JM, Lusher J, Presley R, Shapiro A, Gill J, Manco-Johnson M, Koerper M, Mathew P, Abshire T, Dimichele D, Hoots K, Janco R, Nugent D, Geraghty S, Evatt B, Haemophilia Treatment Center Network Investigators. PMID: 19637999.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    95. The low-frequency isoform of platelet glycoprotein VIb attenuates ligand-mediated signal transduction but not receptor expression or ligand binding. Blood. 2009 Aug 27; 114(9):1893-9. Trifiro E, Williams SA, Cheli Y, Furihata K, Pulcinelli FM, Nugent DJ, Kunicki TJ. PMID: 19465689; PMCID: PMC2738573.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    96. Pathogenesis of chronic immune thrombocytopenia: increased platelet destruction and/or decreased platelet production. Br J Haematol. 2009 Sep; 146(6):585-96. Nugent D, McMillan R, Nichol JL, Slichter SJ. PMID: 19466980.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    97. Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease. Thromb Haemost. 2009 Jan; 101(1):123-33. Kunicki TJ, Williams SA, Nugent DJ, Harrison P, Segal HC, Syed A, Rothwell PM. PMID: 19132198.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    98. Factor XIII deficiency. Haemophilia. 2008 Nov; 14(6):1190-200. Hsieh L, Nugent D. PMID: 19141159.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    99. Platelet function defects. Haemophilia. 2008 Nov; 14(6):1240-9. Simon D, Kunicki T, Nugent D. PMID: 19141164.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    100. Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A. J Thromb Haemost. 2008 02; 6(2):277-83. Powell JS, Nugent DJ, Harrison JA, Soni A, Luk A, Stass H, Gorina E. PMID: 18039351.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    101. Recombinant activated factor VII effectively reverses the anticoagulant effects of heparin, enoxaparin, fondaparinux, argatroban, and bivalirudin ex vivo as measured using thromboelastography. Blood Coagul Fibrinolysis. 2007 Sep; 18(6):547-53. Young G, Yonekawa KE, Nakagawa PA, Blain RC, Lovejoy AE, Nugent DJ. PMID: 17762530.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    102. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia. N Engl J Med. 2007 Aug 09; 357(6):535-44. Manco-Johnson MJ, Abshire TC, Shapiro AD, Riske B, Hacker MR, Kilcoyne R, Ingram JD, Manco-Johnson ML, Funk S, Jacobson L, Valentino LA, Hoots WK, Buchanan GR, DiMichele D, Recht M, Brown D, Leissinger C, Bleak S, Cohen A, Mathew P, Matsunaga A, Medeiros D, Nugent D, Thomas GA, Thompson AA, McRedmond K, Soucie JM, Austin H, Evatt BL. PMID: 17687129.
      View in: PubMed   Mentions: 476     Fields:    Translation:Humans
    103. Pilot dose-finding and safety study of bivalirudin in infants <6 months of age with thrombosis. J Thromb Haemost. 2007 Aug; 5(8):1654-9. Young G, Tarantino MD, Wohrley J, Weber LC, Belvedere M, Nugent DJ. PMID: 17663736.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    104. Efficacy and safety of intravenous anti-D immunoglobulin (Rhophylac) in chronic immune thrombocytopenic purpura. Hematology. 2007 Aug; 12(4):289-95. Aledort LM, Salama A, Kovaleva L, Robak T, Newland AC, Nugent DJ, Brenner B, Zenker O, International Anti-D Study Group. PMID: 17654054.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    105. Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2. Biochim Biophys Acta. 2007 Sep-Oct; 1769(9-10):546-58. Cheli Y, Kanaji S, Jacquelin B, Chang M, Nugent DJ, Kunicki TJ. PMID: 17669516; PMCID: PMC2682338.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    106. Sequential therapy with activated prothrombin complex concentrates and recombinant FVIIa in patients with severe haemophilia and inhibitors: update of our previous experience. Haemophilia. 2007 May; 13(3):244-8. Schneiderman J, Rubin E, Nugent DJ, Young G. PMID: 17498072.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    107. Differential effects of direct thrombin inhibitors and antithrombin-dependent anticoagulants on the dynamics of clot formation. Blood Coagul Fibrinolysis. 2007 Mar; 18(2):97-103. Young G, Yonekawa KE, Nakagawa PA, Blain RC, Lovejoy AE, Nugent DJ. PMID: 17287624.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    108. Individualization of bypassing agent treatment for haemophilic patients with inhibitors utilizing thromboelastography. Haemophilia. 2006 Nov; 12(6):598-604. Young G, Blain R, Nakagawa P, Nugent DJ. PMID: 17083509.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    109. Evidence for the benefits of prophylaxis in the management of hemophilia A. Thromb Haemost. 2006 Oct; 96(4):433-40. Hoots WK, Nugent DJ. PMID: 17003919.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    110. Celecoxib in the treatment of haemophilic synovitis, target joints, and pain in adults and children with haemophilia. Haemophilia. 2006 Sep; 12(5):514-7. Rattray B, Nugent DJ, Young G. PMID: 16919082.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    111. Prophylaxis in rare coagulation disorders -- factor XIII deficiency. Thromb Res. 2006; 118 Suppl 1:S23-8. Nugent DJ. PMID: 16616323.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    112. Single dose of anti-D immune globulin at 75 microg/kg is as effective as intravenous immune globulin at rapidly raising the platelet count in newly diagnosed immune thrombocytopenic purpura in children. J Pediatr. 2006 Apr; 148(4):489-94. Tarantino MD, Young G, Bertolone SJ, Kalinyak KA, Shafer FE, Kulkarni R, Weber LC, Davis ML, Lynn H, Nugent DJ, Acute ITP Study Group. PMID: 16647411.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    113. Safety and pharmacokinetics of recombinant factor XIII-A2 administration in patients with congenital factor XIII deficiency. Blood. 2006 Jul 01; 108(1):57-62. Lovejoy AE, Reynolds TC, Visich JE, Butine MD, Young G, Belvedere MA, Blain RC, Pederson SM, Ishak LM, Nugent DJ. PMID: 16556896.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCellsCTClinical Trials
    114. Immune thrombocytopenic purpura of childhood. Hematology Am Soc Hematol Educ Program. 2006; 97-103. Nugent DJ. PMID: 17124046.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    115. Sustained engraftment post bone marrow transplant despite anti-platelet antibodies in Glanzmann thrombasthenia. Pediatr Blood Cancer. 2005 Dec; 45(7):971-5. Flood VH, Johnson FL, Boshkov LK, Thomas GA, Nugent DJ, Bakke AC, Nicholson HS, Tilford D, Brown MP, Godder KT. PMID: 15768382.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    116. Pediatric stroke and methylenetetrahydrofolate reductase polymorphisms: an examination of C677T and A1298C mutations. J Pediatr Hematol Oncol. 2005 Nov; 27(11):590-3. Rook JL, Nugent DJ, Young G. PMID: 16282888.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    117. Prophylactic recombinant factor VIIa in haemophilia patients with inhibitors. Haemophilia. 2005 May; 11(3):203-7. Young G, McDaniel M, Nugent DJ. PMID: 15876264.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    118. Rofecoxib as adjunctive therapy for haemophilic arthropathy. Haemophilia. 2005 May; 11(3):240-4. Rattray B, Nugent DJ, Young G. PMID: 15876269.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    119. Thrombopoietin initiates demethylation-based transcription of GP6 during megakaryocyte differentiation. Blood. 2005 May 15; 105(10):3888-92. Kanaji S, Kanaji T, Jacquelin B, Chang M, Nugent DJ, Komatsu N, Moroi M, Izuhara K, Kunicki TJ. PMID: 15701720; PMCID: PMC1895081.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    120. The effect of antiplatelet autoantibodies on megakaryocytopoiesis. Int J Hematol. 2005 Feb; 81(2):94-9. McMillan R, Nugent D. PMID: 15765775.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    121. Sequential therapy with activated prothrombin complex concentrate and recombinant factor VIIa in patients with severe haemophilia and inhibitors. Haemophilia. 2004 Jul; 10(4):347-51. Schneiderman J, Nugent DJ, Young G. PMID: 15230948.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    122. Argatroban as an alternative to heparin in extracorporeal membrane oxygenation circuits. Perfusion. 2004; 19(5):283-8. Young G, Yonekawa KE, Nakagawa P, Nugent DJ. PMID: 15506032.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    123. Clinical manifestations of the prothrombin G20210A mutation in children: a pediatric coagulation consortium study. J Thromb Haemost. 2003 May; 1(5):958-62. Young G, Manco-Johnson M, Gill JC, Dimichele DM, Tarantino MD, Abshire T, Nugent DJ. PMID: 12871361.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    124. Painless urethral bleeding: an unusual presentation of Von Willebrand disease. Haemophilia. 2003 May; 9(3):332-5. Armenian S, Raffel JL, Nugent DJ, Young G. PMID: 12694526.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    125. Immune thrombocytopenic purpura (ITP) plasma and purified ITP monoclonal autoantibodies inhibit megakaryocytopoiesis in vitro. Blood. 2003 Aug 01; 102(3):887-95. Chang M, Nakagawa PA, Williams SA, Schwartz MR, Imfeld KL, Buzby JS, Nugent DJ. PMID: 12676790.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansCells
    126. The influence of platelet glycoprotein polymorphisms on receptor function and risk for thrombosis. Vox Sang. 2002 Aug; 83 Suppl 1:85-90. Kunicki TJ, Nugent DJ. PMID: 12617110.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    127. Influence of platelet collagen receptor polymorphisms on risk for arterial thrombosis. Arch Pathol Lab Med. 2002 Mar; 126(3):305-9. Furihata K, Nugent DJ, Kunicki TJ. PMID: 11860304.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    128. Controversies in the treatment of pediatric immune thrombocytopenias. Blood Rev. 2002 Mar; 16(1):15-7. Nugent DJ. PMID: 11913987.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    129. Childhood immune thrombocytopenic purpura. Blood Rev. 2002 Mar; 16(1):27-9. Nugent DJ. PMID: 11913990.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    130. Prevention of Bleeding Complications in Neonates With Liver Failure Undergoing Surgery Using Recombinant Factor VIIa. Hematology. 2001; 6(5):341-6. Young G, Nugent DJ. PMID: 27405529.
      View in: PubMed   Mentions: 1     Fields:    
    131. Current therapy for rare factor deficiencies. Haemophilia. 2001 Jan; 7 Suppl 1:16-22. Di Paola J, Nugent D, Young G. PMID: 11240614.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    132. Sphingosine-1-phosphate: characterization of its inhibition of platelet aggregation. Platelets. 2000 Jun; 11(4):226-32. Nugent D, Xu Y. PMID: 10938902.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    133. Developmental regulation of RNA transcript destabilization by A + U-rich elements is AUF1-dependent. J Biol Chem. 1999 Nov 26; 274(48):33973-8. Buzby JS, Brewer G, Nugent DJ. PMID: 10567360.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    134. Low platelet alpha2beta1 levels in type I von Willebrand disease correlate with impaired platelet function in a high shear stress system. Blood. 1999 Jun 01; 93(11):3578-82. Di Paola J, Federici AB, Mannucci PM, Canciani MT, Kritzik M, Kunicki TJ, Nugent D. PMID: 10339461.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    135. A laparoscopic technique for obtaining ovarian cortical biopsy specimens for fertility conservation in patients with cancer. Fertil Steril. 1999 May; 71(5):948-51. Meirow D, Fasouliotis SJ, Nugent D, Schenker JG, Gosden RG, Rutherford AJ. PMID: 10231063.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    136. Immune thrombocytopenic purpura: why treat? J Pediatr. 1999 Jan; 134(1):3-4. Nugent DJ. PMID: 9880438.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    137. Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2 beta1 density. Blood. 1998 Oct 01; 92(7):2382-8. Kritzik M, Savage B, Nugent DJ, Santoso S, Ruggeri ZM, Kunicki TJ. PMID: 9746778.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    138. PFA-100 system: a new method for assessment of platelet dysfunction. Semin Thromb Hemost. 1998; 24(2):195-202. Mammen EF, Comp PC, Gosselin R, Greenberg C, Hoots WK, Kessler CM, Larkin EC, Liles D, Nugent DJ. PMID: 9579642.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCellsCTClinical Trials
    139. Hereditary variation in platelet integrin alpha 2 beta 1 density is associated with two silent polymorphisms in the alpha 2 gene coding sequence. Blood. 1997 Mar 15; 89(6):1939-43. Kunicki TJ, Kritzik M, Annis DS, Nugent DJ. PMID: 9058714.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    140. Repertoire cloning of a human IgG inhibitor of alpha IIB beta 3 function. The OG idiotype. Mol Immunol. 1995 Jun; 32(9):613-22. Ishida F, Gruel Y, Brojer E, Nugent DJ, Kunicki TJ. PMID: 7543974.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    141. Molecular specificity of anti-IIb/IIIa human antibodies. Semin Thromb Hemost. 1995; 21(1):60-7. Gruel YJ, Nugent DJ, Kunicki TJ. PMID: 7604292.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    142. Further characterization of the thrombasthenia-related idiotype OG. Antiidiotype defines a novel epitope(s) shared by fibrinogen B beta chain, vitronectin, and von Willebrand factor and required for binding to beta 3. J Exp Med. 1994 Dec 01; 180(6):2259-67. Gruel Y, Brojer E, Nugent DJ, Kunicki TJ. PMID: 7525851; PMCID: PMC2191764.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    143. Severe electrical burns in a hemophiliac wearing a medical alert neck chain. Clin Pediatr (Phila). 1994 Jun; 33(6):382-3. Tarantino MD, Nugent DJ. PMID: 8200177.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    144. The estrogen receptor is present in human megakaryocytes. Ann N Y Acad Sci. 1994 Apr 18; 714:293-6. Tarantino MD, Kunicki TJ, Nugent DJ. PMID: 8017783.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    145. Platelet-associated factor XIII as a marker of platelet activation in patients with peripheral vascular disease. Arterioscler Thromb. 1993 Jun; 13(6):857-62. Devine DV, Andestad G, Nugent D, Carter CJ. PMID: 8499406.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    146. Alloimmunization to platelet antigens. Semin Hematol. 1992 Jul; 29(3 Suppl 2):83-8. Nugent DJ. PMID: 1509298.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    147. IVIG in the treatment of children with acute and chronic idiopathic thrombocytopenic purpura and the autoimmune cytopenias. Clin Rev Allergy. 1992 Spring-Summer; 10(1-2):59-71. Nugent DJ. PMID: 1606524.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    148. Human monoclonal autoantibody 2E7 is specific for a peptide sequence of platelet glycoprotein IIb. Localization of the epitope to IIb231-238 with an immunodominant Trp235. J Autoimmun. 1991 Jun; 4(3):415-31. Kunicki TJ, Plow EF, Kekomaki R, Nugent DJ. PMID: 1716897.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    149. Nucleotide sequence of the human autoantibody 2E7 specific for the platelet integrin IIb heavy chain. J Autoimmun. 1991 Jun; 4(3):433-46. Kunicki TJ, Annis DS, Gorski J, Nugent DJ. PMID: 1716898.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    150. Sequence analysis of monoclonal antibodies derived from a patient with idiopathic thrombocytopenic purpura. Autoimmunity. 1990; 8(2):107-13. Hiraiwa A, Nugent DJ, Milner EC. PMID: 2104187.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    151. A human monoclonal autoantibody specific for human platelet glycoprotein IIb (integrin alpha IIb) heavy chain. Hum Antibodies Hybridomas. 1990; 1(2):83-95. Kunicki TJ, Furihata K, Kekomaki R, Scott JP, Nugent DJ. PMID: 1715776.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    152. Human monoclonal autoantibodies to characterize platelet antigens in immune-mediated thrombocytopenia. Blut. 1989 Jul; 59(1):52-8. Nugent DJ. PMID: 2752176.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    153. Isolation and characterization of human platelet glycoprotein IX. Biochem Biophys Res Commun. 1988 Oct 31; 156(2):931-9. Roth GJ, Ozols J, Nugent DJ, Williams SA. PMID: 3056407.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    154. The human fibroblast class II extracellular matrix receptor mediates platelet adhesion to collagen and is identical to the platelet glycoprotein Ia-IIa complex. J Biol Chem. 1988 Apr 05; 263(10):4516-9. Kunicki TJ, Nugent DJ, Staats SJ, Orchekowski RP, Wayner EA, Carter WG. PMID: 2832397.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    155. Glycoprotein Ic-IIa functions as an activation-independent fibronectin receptor on human platelets. J Cell Biol. 1988 Apr; 106(4):1359-64. Piotrowicz RS, Orchekowski RP, Nugent DJ, Yamada KY, Kunicki TJ. PMID: 2966181; PMCID: PMC2115005.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    156. Characterization of an antigen expressed on activated human T cells and platelets. J Immunol. 1988 Apr 01; 140(7):2330-3. Brashem-Stein C, Nugent D, Bernstein ID. PMID: 2832474.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    157. Glycoprotein IIb-IIIa as an immunologic target. Curr Stud Hematol Blood Transfus. 1988; (54):44-63. Kunicki TJ, Furihata K, Nugent D. PMID: 3280255.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    158. On the association of the platelet-specific alloantigen, Pena, with glycoprotein IIIa. Evidence for heterogeneity of glycoprotein IIIa. J Clin Invest. 1987 Dec; 80(6):1624-30. Furihata K, Nugent DJ, Bissonette A, Aster RH, Kunicki TJ. PMID: 2445781; PMCID: PMC442432.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    159. Isolation and characterization of the alpha and beta chains of human platelet glycoprotein Ib. Biochem Biophys Res Commun. 1987 Sep 15; 147(2):526-34. Canfield VA, Ozols J, Nugent D, Roth GJ. PMID: 3632685.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    160. A human monoclonal autoantibody recognizes a neoantigen on glycoprotein IIIa expressed on stored and activated platelets. Blood. 1987 Jul; 70(1):16-22. Nugent DJ, Kunicki TJ, Berglund C, Bernstein ID. PMID: 2439150.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    161. Hepatic veno-occlusive disease after bone marrow transplantation. Immunohistochemical identification of the material within occluded central venules. Am J Pathol. 1987 Jun; 127(3):549-58. Shulman HM, Gown AM, Nugent DJ. PMID: 2438942; PMCID: PMC1899766.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    162. The immunogenicity of platelet membrane glycoproteins. Transfus Med Rev. 1987 Apr; 1(1):21-33. Kunicki TJ, Furihata K, Bull B, Nugent DJ. PMID: 2980263.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    163. Danazol fails to increase factor VIII or IX levels in a double-blind crossover study of patients with haemophilia A and B. Br J Haematol. 1986 Nov; 64(3):493-502. Nugent DJ, Bray GL, Counts RB, Clements MJ, Thompson AR. PMID: 3098273.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    164. Covalent attachment of sulfhydryl-specific, electron spin resonance spin-labels to Fab' fragments of murine monoclonal antibodies that recognize human platelet membrane glycoproteins. Development of membrane protein specific spin probes. Biochemistry. 1986 Sep 09; 25(18):4979-83. Kunicki TJ, Nugent DJ, Piotrowicz RS, Lai CS. PMID: 3021207.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
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