Alin Girnita

Title(s)Clinical Professor, Pathology
SchoolSchool of Medicine
Address1001 Health Sciences Road
Irvine CA 92697-3950
Phone(714) 456-5882
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. ASTCT Consensus Recommendations on Testing and Treatment of Patients with Donor-specific Anti-HLA Antibodies. Transplant Cell Ther. 2024 Sep 10. Kongtim P, Vittayawacharin P, Zou J, Srour S, Shaffer B, Shapiro RM, Varma A, McGuirk J, Dholaria BR, McCurdy SR, DeZern AE, Bejanyan N, Bashey A, Furst S, Castagna L, Mariotti J, Ruggeri A, Bailen R, Teshima T, Xiao-Jun H, Bonfim C, Aung F, Cao K, Carpenter PA, Hamadani M, Askar M, Fernandez-Vina M, Girnita A, Ciurea SO. PMID: 39260570.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Analysis of Cross-sectional and Longitudinal HLA and Anti-viral Responses After COVID Infection in Renal Allograft Recipients: Differences and Correlates. Transplantation. 2022 10 01; 106(10):2085-2091. Girnita AL, Wang L, Colovai AI, Ahearn P, Azzi Y, Menon MC, Fernandez-Vina M, Gebel HM, Steve Woodle E, Cravedi P, Maltzman JS, Akalin E. PMID: 36070571; PMCID: PMC9521392.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Delayed Kinetics of IgG, but Not IgA, Antispike Antibodies in Transplant Recipients following SARS-CoV-2 Infection. J Am Soc Nephrol. 2021 12 01; 32(12):3221-3230. Cravedi P, Ahearn P, Wang L, Yalamarti T, Hartzell S, Azzi Y, Menon MC, Jain A, Billah M, Fernandez-Vina M, Gebel HM, Woodle ES, Haddad NS, Morrison-Porter A, Lee FE, Sanz I, Akalin E, Girnita A, Maltzman JS. PMID: 34599041; PMCID: PMC8638399.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    4. Reducing Donor-specific Antibody During Acute Rejection Diminishes Long-term Renal Allograft Loss: Comparison of Early and Late Rejection. Transplantation. 2020 11; 104(11):2403-2414. Lichvar AB, Tremblay S, Leino AD, Shields AR, Cardi MA, Abu Jawdeh BG, Govil A, Kremer J, Cuffy M, Paterno F, Diwan T, Brailey P, Girnita A, Alloway RR, Woodle ES. PMID: 32000256.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    5. Proteasomal adaptations underlying carfilzomib-resistance in human bone marrow plasma cells. Am J Transplant. 2020 02; 20(2):399-410. Woodle ES, Tremblay S, Brailey P, Girnita A, Alloway RR, Aronow B, Dasgupta N, Ebstein F, Kloetzel PM, Lee MJ, Kim KB, Singh H, Driscoll JJ. PMID: 31595669; PMCID: PMC6984988.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    6. A prospective, iterative, adaptive trial of carfilzomib-based desensitization. Am J Transplant. 2020 02; 20(2):411-421. Tremblay S, Driscoll JJ, Rike-Shields A, Hildeman DA, Alloway RR, Girnita AL, Brailey PA, Woodle ES. PMID: 31550069; PMCID: PMC7872208.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCellsCTClinical Trials
    7. IGG3 anti-HLA donor-specific antibodies and graft function in pediatric kidney transplant recipients. Pediatr Transplant. 2018 08; 22(5):e13219. Hamdani G, Goebel JW, Brailey P, Portwood EA, Hooper DK, Girnita AL. PMID: 29855114.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. Successful Simultaneous Liver-Kidney Transplantation in the Presence of Multiple High-Titered Class I and II Antidonor HLA Antibodies. Transplant Direct. 2016 Dec; 2(12):e121. Paterno F, Girnita A, Brailey P, Witte D, Wang J, Cuffy MC, Diwan T, Tremblay S, Revollo JY, Alloway RR, Schoech MR, Anwar N, Shah SA, Woodle SE. PMID: 27990486; PMCID: PMC5142368.
      View in: PubMed   Mentions: 9  
    9. Acute Rejection Clinically Defined Phenotypes Correlate With Long-term Renal Allograft Survival. Transplantation. 2015 Oct; 99(10):2167-73. Krisl JC, Alloway RR, Shield AR, Govil A, Mogilishetty G, Cardi M, Diwan T, Abu Jawdeh BG, Girnita A, Witte D, Woodle ES. PMID: 25856409.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    10. Case Report: Successful Living Donor Kidney Transplantation in a Highly Human Leukocyte Antigen-Sensitized Recipient With a Positive Cytotoxic Crossmatch Using Bortezomib-Based Desensitization Without Intravenous Immunoglobulin. Transplant Proc. 2015 Sep; 47(7):2254-7. Revollo JY, Cuffy MC, Abu Jawdeh BG, Paterno F, Girnita A, Brailey P, Alloway RR, Woodle ES. PMID: 26361693.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Prospective iterative trial of proteasome inhibitor-based desensitization. Am J Transplant. 2015 Jan; 15(1):101-18. Woodle ES, Shields AR, Ejaz NS, Sadaka B, Girnita A, Walsh RC, Alloway RR, Brailey P, Cardi MA, Abu Jawdeh BG, Roy-Chaudhury P, Govil A, Mogilishetty G. PMID: 25534446.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    12. Randomized controlled pilot study of B cell-targeted induction therapy in HLA sensitized kidney transplant recipients. Am J Transplant. 2013 Dec; 13(12):3142-54. Ejaz NS, Shields AR, Alloway RR, Sadaka B, Girnita AL, Mogilishetty G, Cardi M, Woodle ES. PMID: 24266968.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    13. Prospective evaluation of the toxicity profile of proteasome inhibitor-based therapy in renal transplant candidates and recipients. Transplantation. 2012 Aug 27; 94(4):352-61. Schmidt N, Alloway RR, Walsh RC, Sadaka B, Shields AR, Girnita AL, Hanseman DJ, Woodle ES. PMID: 22836132.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    14. Proteasome inhibitor-based therapy for antibody-mediated rejection. Kidney Int. 2012 Jun; 81(11):1067-74. Walsh RC, Alloway RR, Girnita AL, Woodle ES. PMID: 22336990.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    15. Proteasome inhibitor therapy for antibody-mediated rejection. Pediatr Transplant. 2011 Sep; 15(6):548-56. Woodle ES, Walsh RC, Alloway RR, Girnita A, Brailey P. PMID: 21884344.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    16. Proteasome inhibitor treatment of antibody-mediated allograft rejection. Curr Opin Organ Transplant. 2011 Aug; 16(4):434-8. Woodle ES, Alloway RR, Girnita A. PMID: 21753709.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    17. Early and late acute antibody-mediated rejection differ immunologically and in response to proteasome inhibition. Transplantation. 2011 Jun 15; 91(11):1218-26. Walsh RC, Brailey P, Girnita A, Alloway RR, Shields AR, Wall GE, Sadaka BH, Cardi M, Tevar A, Govil A, Mogilishetty G, Roy-Chaudhury P, Woodle ES. PMID: 21617586.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    18. Antihuman leukocyte antigen–specific antibody strength determined by complement-dependent or solid-phase assays can predict positive donor-specific crossmatches. Arch Pathol Lab Med. 2010 Oct; 134(10):1534-40. Batal I, Zeevi A, Lunz JG, Aggarwal N, Shapiro R, Randhawa P, Girnita A. PMID: 20923311.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    19. Liver transplant recipients weaned off immunosuppression lack circulating donor-specific antibodies. Hum Immunol. 2010 Mar; 71(3):274-6. Girnita A, Mazariegos GV, Castellaneta A, Reyes J, Bentlejewski C, Thomson AW, Zeevi A. PMID: 20006667.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    20. The significance of renal C4d staining in patients with BK viruria, viremia, and nephropathy. Mod Pathol. 2009 Nov; 22(11):1468-76. Batal I, Zainah H, Stockhausen S, Basu A, Tan H, Shapiro R, Zeevi A, Girnita A, Randhawa P. PMID: 19734851.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    21. Genotypic variation and phenotypic characterization of granzyme B gene polymorphisms. Transplantation. 2009 Jun 27; 87(12):1801-6. Girnita DM, Webber SA, Brooks MM, Ferrell R, Girnita AL, Burckart GJ, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin JK, Naftel D, Zeevi A. PMID: 19543056; PMCID: PMC2739874.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Emerging role of donor-specific anti-human leukocyte antigen antibody determination for clinical management after solid organ transplantation. Hum Immunol. 2009 Aug; 70(8):645-50. Zeevi A, Lunz JG, Shapiro R, Randhawa P, Mazariegos G, Webber S, Girnita A. PMID: 19527760.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    23. Neutrophilic tubulitis as a marker for urinary tract infection in renal allograft biopsies with C4d deposition. Transplantation. 2009 Apr 15; 87(7):1013-8. Gupta G, Shapiro R, Girnita A, Batal I, McCauley J, Basu A, Tan H, Randhawa P. PMID: 19352120.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    24. Bortezomib-based treatment of antibody mediated rejection in pancreas allograft recipients. Clin Transpl. 2009; 443-53. Govil A, Walsh RC, Tevar A, Alloway R, Roy-Chaudhury P, Mogilishetty G, Wall GE, Brailey P, Girnita A, Woodle ES. PMID: 20524313.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. Pediatric intestinal retransplantation: techniques, management, and outcomes. Transplantation. 2008 Dec 27; 86(12):1777-82. Mazariegos GV, Soltys K, Bond G, Girnita A, Machaidze Z, Jaffe R, Green M, Martin D, Zeevi A, Squires R, Perez G, Abu-Elmagd K, Sindhi R. PMID: 19104421.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    26. Clinical significance of the distribution of C4d deposits in different anatomic compartments of the allograft kidney. Mod Pathol. 2008 Dec; 21(12):1490-8. Batal I, Girnita A, Zeevi A, Saab BA, Stockhausen S, Shapiro R, Basu A, Tan H, Morgan C, Randhawa P. PMID: 18820671.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    27. Anti-human leukocyte antigen antibodies, vascular C4d deposition and increased soluble c4d in broncho-alveolar lavage of lung allografts. Transplantation. 2008 Jul 27; 86(2):342-7. Girnita AL, Lee TM, McCurry KR, Baldwin WM, Yousem SA, Detrick B, Pilewski J, Toyoda Y, Jelinek L, Lomago J, Zaldonis D, Spichty KJ, Zeevi A. PMID: 18645500.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    28. Genetic polymorphisms impact the risk of acute rejection in pediatric heart transplantation: a multi-institutional study. Transplantation. 2008 Jun 15; 85(11):1632-9. Girnita DM, Brooks MM, Webber SA, Burckart GJ, Ferrell R, Zdanowicz G, DeCroo S, Smith L, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin JK, Ranganathan S, Naftel D, Girnita AL, Zeevi A. PMID: 18551071.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    29. Alemtuzumab preconditioning with tacrolimus monotherapy-the impact of serial monitoring for donor-specific antibody. Transplantation. 2008 Apr 27; 85(8):1125-32. Shapiro R, Zeevi A, Basu A, Tan HP, Kayler LK, Blisard DM, Thai NL, Girnita AL, Randhawa PS, Gray EA, Marcos A, Starzl TE. PMID: 18431232; PMCID: PMC2952475.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    30. Measurements of global cell-mediated immunity in renal transplant recipients with BK virus reactivation. Am J Clin Pathol. 2008 Apr; 129(4):587-91. Batal I, Zeevi A, Heider A, Girnita A, Basu A, Tan H, Shapiro R, Randhawa P. PMID: 18343786.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    31. Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d. Transplantation. 2008 Mar 27; 85(6):813-20. Kayler LK, Kiss L, Sharma V, Mohanka R, Zeevi A, Girnita A, Shapiro R, Randhawa PS. PMID: 18360261.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    32. Retransplant candidates have donor-specific antibodies that react with structurally defined HLA-DR,DQ,DP epitopes. Transpl Immunol. 2008 Feb; 18(4):352-60. Duquesnoy RJ, Awadalla Y, Lomago J, Jelinek L, Howe J, Zern D, Hunter B, Martell J, Girnita A, Zeevi A. PMID: 18158123; PMCID: PMC2724998.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    33. Survival in allosensitized children after listing for cardiac transplantation. J Heart Lung Transplant. 2007 Jun; 26(6):565-71. Feingold B, Bowman P, Zeevi A, Girnita AL, Quivers ES, Miller SA, Webber SA. PMID: 17543778.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansPHPublic Health
    34. Increased lung allograft failure in patients with HLA-specific antibody. Clin Transpl. 2007; 231-9. Girnita AL, McCurry KR, Zeevi A. PMID: 18637473.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    35. Disparate distribution of 16 candidate single nucleotide polymorphisms among racial and ethnic groups of pediatric heart transplant patients. Transplantation. 2006 Dec 27; 82(12):1774-80. Girnita DM, Webber SA, Ferrell R, Burckart GJ, Brooks MM, McDade KK, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin JK, Girnita AL, Zeevi A. PMID: 17198275.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    36. Anti-HLA alloantibodies in pediatric solid organ transplantation. Pediatr Transplant. 2006 Mar; 10(2):146-53. Girnita AL, Webber SA, Zeevi A. PMID: 16573598.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    37. HLA antibody analysis: sensitivity, specificity, and clinical significance in solid organ transplantation. Immunol Res. 2006; 36(1-3):255-64. Zeevi A, Girnita A, Duquesnoy R. PMID: 17337786.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    38. Antibody-mediated rejection in lung transplantation: case reports. Clin Transpl. 2006; 508-10. Girnita AL, McCurry KR, Yousem SA, Pilewski J, Zeevi A. PMID: 18365413.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Early outcomes in human lung transplantation with Thymoglobulin or Campath-1H for recipient pretreatment followed by posttransplant tacrolimus near-monotherapy. J Thorac Cardiovasc Surg. 2005 Aug; 130(2):528-37. McCurry KR, Iacono A, Zeevi A, Yousem S, Girnita A, Husain S, Zaldonis D, Johnson B, Hattler BG, Starzl TE. PMID: 16077423; PMCID: PMC3035836.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    40. C4d deposition in lung allografts is associated with circulating anti-HLA alloantibody. Transpl Immunol. 2005 Oct; 15(1):63-8. Ionescu DN, Girnita AL, Zeevi A, Duquesnoy R, Pilewski J, Johnson B, Studer S, McCurry KR, Yousem SA. PMID: 16223674.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    41. Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath. J Am Coll Surg. 2005 Apr; 200(4):505-15; quiz A59-61. Shapiro R, Basu A, Tan H, Gray E, Kahn A, Randhawa P, Murase N, Zeevi A, Girnita A, Metes D, Ness R, Bass DC, Demetris AJ, Fung JJ, Marcos A, Starzl TE. PMID: 15804464; PMCID: PMC2980295.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    42. Serum analysis after transplant nephrectomy reveals restricted antibody specificity patterns against structurally defined HLA class I mismatches. Transpl Immunol. 2005 Mar; 14(1):53-62. Adeyi OA, Girnita AL, Howe J, Marrari M, Awadalla Y, Askar M, Martell J, Zeevi A, Shapiro R, Nalesnik M, Randhawa P, Demetris AJ, Duquesnoy RJ. PMID: 15814283.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    43. Impact of ELISA-detected anti-HLA antibodies on pediatric cardiac allograft outcome. Hum Immunol. 2005 May; 66(5):513-8. Di Filippo S, Girnita A, Webber SA, Tsao S, Boyle GJ, Miller SA, Gandhi SK, Zeevi A. PMID: 15935888.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    44. HLA-specific antibodies are risk factors for lymphocytic bronchiolitis and chronic lung allograft dysfunction. Am J Transplant. 2005 Jan; 5(1):131-8. Girnita AL, Duquesnoy R, Yousem SA, Iacono AT, Corcoran TE, Buzoianu M, Johnson B, Spichty KJ, Dauber JH, Burckart G, Griffith BP, McCurry KR, Zeevi A. PMID: 15636621.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    45. HLA-specific antibodies are associated with high-grade and persistent-recurrent lung allograft acute rejection. J Heart Lung Transplant. 2004 Oct; 23(10):1135-41. Girnita AL, McCurry KR, Iacono AT, Duquesnoy R, Corcoran TE, Awad M, Spichty KJ, Yousem SA, Burckart G, Dauber JH, Griffith BP, Zeevi A. PMID: 15477106.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    46. Graft versus host disease in intestinal transplantation. Am J Transplant. 2004 Sep; 4(9):1459-65. Mazariegos GV, Abu-Elmagd K, Jaffe R, Bond G, Sindhi R, Martin L, Macedo C, Peters J, Girnita A, Reyes J. PMID: 15307833.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    47. Acute humoral rejection of human lung allografts and elevation of C4d in bronchoalveolar lavage fluid. Am J Transplant. 2004 Aug; 4(8):1323-30. Miller GG, Destarac L, Zeevi A, Girnita A, McCurry K, Iacono A, Murray JJ, Crowe D, Johnson JE, Ninan M, Milstone AP. PMID: 15268735.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
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