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Boiko, Alexander Davidovic

TitleAssistant Professor
InstitutionUniversity of California, Irvine
DepartmentMolecular Biology & Biochemistry
Address3022 Gross Hall
Zot 3900
Irvine CA 92697
Phone(949) 824-9953
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    Collapse Research 
    Collapse Research Activities and Funding
    Isolation and Characterization of Tumor Stem Cells from Melanoma Patients
    NIH/NCI R00CA154960Apr 1, 2013 - Mar 31, 2016
    Role: Principal Investigator
    Isolation and Characterization of Tumor Stem Cells from Melanoma Patients
    NIH/NCI K99CA154960Aug 9, 2011 - Jul 31, 2013
    Role: Principal Investigator
    Isolation and Characterization of Melanoma Tumor Stem Cells
    NIH/NCI F32CA126252Dec 1, 2007 - Nov 30, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ngo M, Han A, Lakatos A, Sahoo D, Hachey SJ, Weiskopf K, Beck AH, Weissman IL, Boiko AD. Antibody Therapy Targeting CD47 and CD271 Effectively Suppresses Melanoma Metastasis in Patient-Derived Xenografts. Cell Rep. 2016 08 09; 16(6):1701-1716. PMID: 27477289.
      View in: PubMed
    2. Hachey SJ, Boiko AD. Therapeutic implications of melanoma heterogeneity. Exp Dermatol. 2016 07; 25(7):497-500. PMID: 27060971.
      View in: PubMed
    3. Dimov IK, Boiko AD. Profiling Melanoma Heterogeneity Using Microwell RNA Cytometry. Methods Mol Biol. 2016 Apr 16. PMID: 27083169.
      View in: PubMed
    4. Boiko AD. Isolation of melanoma tumor-initiating cells from surgical tissues. Methods Mol Biol. 2013; 961:253-9. PMID: 23325649; PMCID: PMC4009373.
    5. Razorenova OV, Finger EC, Colavitti R, Chernikova SB, Boiko AD, Chan CK, Krieg A, Bedogni B, LaGory E, Weissman IL, Broome-Powell M, Giaccia AJ. VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):1931-6. PMID: 21233420; PMCID: PMC3033256.
    6. Boiko AD, Razorenova OV, van de Rijn M, Swetter SM, Johnson DL, Ly DP, Butler PD, Yang GP, Joshua B, Kaplan MJ, Longaker MT, Weissman IL. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature. 2010 Jul 01; 466(7302):133-7. PMID: 20596026; PMCID: PMC2898751.
    7. Boiko AD, Porteous S, Razorenova OV, Krivokrysenko VI, Williams BR, Gudkov AV. A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation. Genes Dev. 2006 Jan 15; 20(2):236-52. PMID: 16418486; PMCID: PMC1356114.
    8. Lu T, Burdelya LG, Swiatkowski SM, Boiko AD, Howe PH, Stark GR, Gudkov AV. Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells. Proc Natl Acad Sci U S A. 2004 May 04; 101(18):7112-7. PMID: 15118089; PMCID: PMC406474.
    9. Zou X, Ray D, Aziyu A, Christov K, Boiko AD, Gudkov AV, Kiyokawa H. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence. Genes Dev. 2002 Nov 15; 16(22):2923-34. PMID: 12435633; PMCID: PMC187486.
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