Alexander Davidovic Boiko
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Title(s) | Assistant Professor, Molecular Biology & Biochemistry |
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Phone | (949) 824-9953 |
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vCard | Download vCard |
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Research Bibliographic
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Han A, Li C, Zahed T, Wong M, Smith I, Hoedel K, Green D, Boiko AD. Calreticulin is a Critical Cell Survival Factor in Malignant Neoplasms. PLoS Biol. 2019 Sep; 17(9):e3000402. PMID: 31568485.
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Filipp FV, Li C, Boiko AD. CD271 is a molecular switch with divergent roles in melanoma and melanocyte development. Sci Rep. 2019 May 22; 9(1):7696. PMID: 31118427.
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Li C, Nguyen V, Clark KN, Zahed T, Sharkas S, Filipp FV, Boiko AD. Down-regulation of FZD3 receptor suppresses growth and metastasis of human melanoma independently of canonical WNT signaling. Proc Natl Acad Sci U S A. 2019 Feb 21. PMID: 30792348.
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Ngo M, Han A, Lakatos A, Sahoo D, Hachey SJ, Weiskopf K, Beck AH, Weissman IL, Boiko AD. Antibody Therapy Targeting CD47 and CD271 Effectively Suppresses Melanoma Metastasis in Patient-Derived Xenografts. Cell Rep. 2016 08 09; 16(6):1701-1716. PMID: 27477289.
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Hachey SJ, Boiko AD. Therapeutic implications of melanoma heterogeneity. Exp Dermatol. 2016 07; 25(7):497-500. PMID: 27060971.
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Dimov IK, Boiko AD. Profiling Melanoma Heterogeneity Using Microwell RNA Cytometry. Methods Mol Biol. 2016 Apr 16. PMID: 27083169.
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Boiko AD. Isolation of melanoma tumor-initiating cells from surgical tissues. Methods Mol Biol. 2013; 961:253-9. PMID: 23325649.
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Razorenova OV, Finger EC, Colavitti R, Chernikova SB, Boiko AD, Chan CK, Krieg A, Bedogni B, LaGory E, Weissman IL, Broome-Powell M, Giaccia AJ. VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):1931-6. PMID: 21233420.
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Boiko AD, Razorenova OV, van de Rijn M, Swetter SM, Johnson DL, Ly DP, Butler PD, Yang GP, Joshua B, Kaplan MJ, Longaker MT, Weissman IL. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature. 2010 Jul 01; 466(7302):133-7. PMID: 20596026.
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Boiko AD, Porteous S, Razorenova OV, Krivokrysenko VI, Williams BR, Gudkov AV. A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation. Genes Dev. 2006 Jan 15; 20(2):236-52. PMID: 16418486.
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Lu T, Burdelya LG, Swiatkowski SM, Boiko AD, Howe PH, Stark GR, Gudkov AV. Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells. Proc Natl Acad Sci U S A. 2004 May 04; 101(18):7112-7. PMID: 15118089.
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Zou X, Ray D, Aziyu A, Christov K, Boiko AD, Gudkov AV, Kiyokawa H. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence. Genes Dev. 2002 Nov 15; 16(22):2923-34. PMID: 12435633.
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Axenovich SA, Kazarov AR, Boiko AD, Armin G, Roninson IB, Gudkov AV. Altered expression of ubiquitous kinesin heavy chain results in resistance to etoposide and hypersensitivity to colchicine: mapping of the domain associated with drug response. Cancer Res. 1998 Aug 01; 58(15):3423-8. PMID: 9699675.
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